For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VSAEEQDTRSGGIQVIARAAELLRVLQAHPGGLSQAEIGERVGMARSTVSRILNALEDEGLVASRGARGP YRLGPEITRMATTVRLGVVTEMHPFLTELSRELDETVDLSILDGDRADVVDQVVPPQRLRAVSAVGESFP LYCCANGKALLAALPPERQARALPSRLAPLTANTITDRAALRDELNRIRVDGVAYDREEQTEGICAVGAV LRGVSVELVAVSVPVPAQRFYGREAELAGALLAWVSKVDAWFNGTEDRK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1719 | - | - | 100% (259) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. tuberculosis H37Rv | Rv1773c | - | 3e-36 | 40.08% (242) | transcriptional regulatory protein |
| M. tuberculosis H37Rv | Rv2989 | - | 8e-14 | 30.59% (219) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1748 | - | 1e-143 | 100.00% (259) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_3087 | - | 3e-24 | 34.22% (225) | transcriptional regulator, TrmB |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4493 | - | 1e-34 | 34.93% (229) | IclR family transcriptional regulator |
| M. marinum M | MMAR_4423 | - | 1e-20 | 32.89% (228) | transcriptional regulatory protein |
| M. avium 104 | MAV_3513 | - | 7e-23 | 32.37% (241) | transcriptional regulator, IclR family protein |
| M. smegmatis MC2 155 | MSMEG_2483 | - | 1e-29 | 36.12% (227) | transcriptional regulator, IclR family protein |
| M. thermoresistible (build 8) | TH_3251 | - | 4e-14 | 32.20% (205) | PUTATIVE putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_1967 | - | 5e-17 | 33.76% (237) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0155 | - | 2e-34 | 37.87% (235) | regulatory proteins, IclR |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1719|M.tuberculosis_H37Rv -------MSAEEQ-------DTRSGGIQVIARAAELLRVLQAHPGGLSQA
Mb1748|M.bovis_AF2122/97 -------MSAEEQ-------DTRSGGIQVIARAAELLRVLQAHPGGLSQA
Mvan_0155|M.vanbaalenii_PYR-1 -------MPGADQNGRIDATEGRDDGLQVLRRAAAALDEIATAPGRLRLV
MAB_4493|M.abscessus_ATCC_1997 --------------------------MSVLTRAAQILDALAESNSGLSVR
MSMEG_2483|M.smegmatis_MC2_155 --------------------------MADIGRSTLVLDALAEASKPLTLS
Mflv_3087|M.gilvum_PYR-GCK --------MAQHDKTSTTSPTDAPAAVQSVDRALQVLEIVAAH-GQAGVT
MMAR_4423|M.marinum_M MSSGISSMIMGTGNDGGASESDPAPTVQSVDRALLVLELLADL-GKAGVT
MAV_3513|M.avium_104 MPAKRARVAGPAAAAPAADALAPQYPIESVDNALKLLLLLGEQ-PEIRLS
MUL_1967|M.ulcerans_Agy99 --------------------MRQDSGIGVIDKAVGLLRATAKS--PCGLA
TH_3251|M.thermoresistible__bu MTATLDQPTPNTTVKRTGTERTGETPSAVLDRISLVLDAFDGP-GRLTLA
: . *
Rv1719|M.tuberculosis_H37Rv EIGERVGMARSTVSRILNALEDEGLVASRGARGPYRLGPEITRMATTV--
Mb1748|M.bovis_AF2122/97 EIGERVGMARSTVSRILNALEDEGLVASRGARGPYRLGPEITRMATTV--
Mvan_0155|M.vanbaalenii_PYR-1 DVGTNLGLAKSTARRLLVALVDVGFAAVDDS-GRYHLGDRLLGLTSAD--
MAB_4493|M.abscessus_ATCC_1997 ELAEATGLPKSSVHRIVQELTVSQYVMAGGRGGSYQLGPGLLKLGLNN--
MSMEG_2483|M.smegmatis_MC2_155 ELATRTGLPRSTVHRIVQSLERSLYLVRGVDRHGYSLGPGLLKFGMNA--
Mflv_3087|M.gilvum_PYR-GCK EIAAELGVHKSTVSRLVAVLEARGYVEQVSERGKYRLGFAIPRLAHVAGG
MMAR_4423|M.marinum_M EVADELGVHKSTASRLITALEARGYVEQLSDRGKYQLGIGVSRLARARSG
MAV_3513|M.avium_104 EATRYLGVASSTAHRLLAMLAYRGFVRQDPVSKAYLPGPSLTGVAFAIFG
MUL_1967|M.ulcerans_Agy99 ELCERTGLPRATAYRLAAALEVHRLLG-RDEDGRWGLGPAITELAAHV--
TH_3251|M.thermoresistible__bu QVVRRTGLPRSSAHRMLERLVQLRWLRRDGR--DYELGMRLVELGSLAVH
: *: ::. *: * : * : .
Rv1719|M.tuberculosis_H37Rv RLGVVTEMHPFLTELSRELDETVDLSILDGDRADVVDQVVPPQRLRAVSA
Mb1748|M.bovis_AF2122/97 RLGVVTEMHPFLTELSRELDETVDLSILDGDRADVVDQVVPPQRLRAVSA
Mvan_0155|M.vanbaalenii_PYR-1 GSTLAARLRPVIERLALATGETVDLSVLRGRQMWFVDQIESAHRLRAVSA
MAB_4493|M.abscessus_ATCC_1997 RRQFVAPMRKAIATVAREVNENIDLAMLSGGELVIIEQIATVRNLPTVTV
MSMEG_2483|M.smegmatis_MC2_155 HLRLLAGNRPLLARLVREVGENVELAIFSGREVVVVDQLASVNRLHGVTK
Mflv_3087|M.gilvum_PYR-GCK QNDLVKLGQAACDMLSAGVGETANLAVLDADRIVNIVEAIGPSEITLRTW
MMAR_4423|M.marinum_M HSDLVKLSQDACDKLAADLGETANLAILDENRAVNIVEAVSTAEIALQTW
MAV_3513|M.avium_104 RLDIARSAAPIMRALSEQLRETVHVGMLDGASVRFVAAVEGPAAVRVASR
MUL_1967|M.ulcerans_Agy99 DDPLLTAGATVLPRLCETTGESVQLYRREGTSRVCVAALEPPAGLRDTVP
TH_3251|M.thermoresistible__bu QDRLHRAAIPRLHELHAATGLVVHLAVLDGSDVVYLEKVGSRLAAAIPTR
. : .: :
Rv1719|M.tuberculosis_H37Rv VGESFPLYCCANGKALLAALPPERQ----ARALPSRLAPLTANTITDRAA
Mb1748|M.bovis_AF2122/97 VGESFPLYCCANGKALLAALPPERQ----ARALPSRLAPLTANTITDRAA
Mvan_0155|M.vanbaalenii_PYR-1 VGGRFPLHDTANGKAALALMEDD--------AIP--------------DG
MAB_4493|M.abscessus_ATCC_1997 VGRTFALHASSIGKALLSQLPPDQV----RNMLPADLEVFTTNTITDVTA
MSMEG_2483|M.smegmatis_MC2_155 VGKSFSLHASCIGLALLAHLPDDQV----AGLLSPPLQRFTEHTVTDLPA
Mflv_3087|M.gilvum_PYR-GCK VGQSCPAYATSSGKVLLAGLDPAELP---ARIR-PPLTEFTDSTLCGLAE
MMAR_4423|M.marinum_M VGQSCPVHATSSGKVLLAGLDADEVR---QRVG-ATLDSFTENTIVTIDA
MAV_3513|M.avium_104 LGRALPAHCTSTGKVMLAQLSAAELR---ALLPRERLKRITAHSIGSRAA
MUL_1967|M.ulcerans_Agy99 VGARLPMTAGSGAKVLLAHSDPATQQ---AVLP-------------TAKF
TH_3251|M.thermoresistible__bu VGGRRPANCAAVGKAILAYAEDDGVLSGTG-----PLPRNTKYSISDPAR
:* . . . . *:
Rv1719|M.tuberculosis_H37Rv LRDELNRIRVDGVAYDREEQTEGICAVGAVLR-GVSVELVAVSVPVPAQR
Mb1748|M.bovis_AF2122/97 LRDELNRIRVDGVAYDREEQTEGICAVGAVLR-GVSVELVAVSVPVPAQR
Mvan_0155|M.vanbaalenii_PYR-1 LLDEIAEVRRTGIAYDRDEHTAGISAAGIAVR-LPGGHVVAISVPAPTER
MAB_4493|M.abscessus_ATCC_1997 LLRELDDVRSTGVAFDHEEHDVGISSVAVPLP-HPAAIPQAMAIVAPTPR
MSMEG_2483|M.smegmatis_MC2_155 IMGRLDEVRRTQIAVDTEEHDVGICAVATAFP-GPTGALQAVAVVMPTAR
Mflv_3087|M.gilvum_PYR-GCK LQDELAAVRERGWACVREELEVGLNAVAAPVYDVHAQVIAALSVSGPSYR
MMAR_4423|M.marinum_M LEAQLAATRAAGWASAREELEIGLNAVAAPVYDSTGRVAAALSVSGPAYR
MAV_3513|M.avium_104 LETELAAIRERGYATNREESEEGVASVAVPIPTRAPGLRLALNAAAPQNR
MUL_1967|M.ulcerans_Agy99 TDRVLAEVRRRGWAQSVAEREPGVASVSAPVRDGRGVVVAAISVSGPIDR
TH_3251|M.thermoresistible__bu LRAELAKVRAHGVAFDREESLPGIGCVAAPIG-DPGEAVAAISVCGPMNQ
: * * * *: ... . *: * :
Rv1719|M.tuberculosis_H37Rv FYGRE----AELAGALLAWVSKVDAWFNGTEDRK----------------
Mb1748|M.bovis_AF2122/97 FYGRE----AELAGALLAWVSKVDAWFNGTEDRK----------------
Mvan_0155|M.vanbaalenii_PYR-1 FRAQE----STIVDALRAAAADP-VWAGGVS-------------------
MAB_4493|M.abscessus_ATCC_1997 FAQRK----TKYVAALDSLTKRANST------------------------
MSMEG_2483|M.smegmatis_MC2_155 FRAKR----ERAVESLQRINPLLAHRN-----------------------
Mflv_3087|M.gilvum_PYR-GCK LAVDR----FDEVAKQTVAAAEQISRRLGWTTRN----------------
MMAR_4423|M.marinum_M LPAAD----FEEVAQQTIAAADAVSRGLGWTDRIS---------------
MAV_3513|M.avium_104 LDAAR----YPAVAAALVAAAKEIGDQLG---------------------
MUL_1967|M.ulcerans_Agy99 IGRRP----GARWAADLLAAADELARRL----------------------
TH_3251|M.thermoresistible__bu MAFDHRLVAPVRMAALGIWRAMEGARQRVVPTLQQVRPLRPGPTAQSLSH
:
Rv1719|M.tuberculosis_H37Rv -----------------------
Mb1748|M.bovis_AF2122/97 -----------------------
Mvan_0155|M.vanbaalenii_PYR-1 -----------------------
MAB_4493|M.abscessus_ATCC_1997 -----------------------
MSMEG_2483|M.smegmatis_MC2_155 -----------------------
Mflv_3087|M.gilvum_PYR-GCK -----------------------
MMAR_4423|M.marinum_M -----------------------
MAV_3513|M.avium_104 -----------------------
MUL_1967|M.ulcerans_Agy99 -----------------------
TH_3251|M.thermoresistible__bu SALSHPAQSHPARSHRADTRRFA