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PGTVQSVERAAAILQLLGIEDESLGLVQIAGALGLAKGTAHGLLRTLHGVGFVEQDASGRYRLGPDLFHL GSTQLDLNELKARALNWADALAARTGEAVRVAAFRAGRAVVAHHVFRADATAQVLEVGAIVPLHASALGK VLLAFDPGAARSLGALDSLTYRTITNRAQLQHELADTRDRGWAASVEEEQPGVASIAAPVRDRGGYVVAS IGISGDVERLCDHRARPLERLAELVVRAGRSVSREFGHGREL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6757 | - | - | 100% (253) | glycerol operon regulatory protein |
| M. smegmatis MC2 155 | MSMEG_2125 | - | 3e-36 | 43.32% (247) | glycerol operon regulatory protein |
| M. smegmatis MC2 155 | MSMEG_2386 | - | 4e-21 | 30.13% (239) | transcriptional regulator, IclR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3013 | - | 4e-18 | 30.25% (238) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_3087 | - | 5e-29 | 36.47% (255) | transcriptional regulator, TrmB |
| M. tuberculosis H37Rv | Rv2989 | - | 4e-18 | 30.25% (238) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3295 | - | 1e-21 | 32.62% (233) | IclR family transcriptional regulator |
| M. marinum M | MMAR_4423 | - | 5e-29 | 36.51% (252) | transcriptional regulatory protein |
| M. avium 104 | MAV_3839 | - | 7e-20 | 31.82% (220) | transcriptional regulator, IclR family protein |
| M. thermoresistible (build 8) | TH_2042 | - | 3e-21 | 30.77% (234) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. ulcerans Agy99 | MUL_1967 | - | 3e-19 | 32.13% (221) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0155 | - | 1e-19 | 35.65% (216) | regulatory proteins, IclR |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3087|M.gilvum_PYR-GCK --------MAQHDKTSTTSPTDAPAAVQSVDRALQVLEIVAAHG-QAGVT
MMAR_4423|M.marinum_M MSSGISSMIMGTGNDGGASESDPAPTVQSVDRALLVLELLADLG-KAGVT
MSMEG_6757|M.smegmatis_MC2_155 ----------------------MPGTVQSVERAAAILQLLGIEDESLGLV
Mb3013|M.bovis_AF2122/97 --------------------MRQHSGIGVLDKAVGVLHAVAESP--CGLA
Rv2989|M.tuberculosis_H37Rv --------------------MRQHSGIGVLDKAVGVLHAVAESP--CGLA
MAV_3839|M.avium_104 ---------------------------------MGVLHTVAQSP--CGLA
MUL_1967|M.ulcerans_Agy99 --------------------MRQDSGIGVIDKAVGLLRATAKSP--CGLA
TH_2042|M.thermoresistible__bu --------------------MRKDSGIGVLDKAVSVLHSVAESP--CGLA
MAB_3295|M.abscessus_ATCC_1997 --------------------MRQHSGIGVLDKAVQVLTAIGDSP--CGLA
Mvan_0155|M.vanbaalenii_PYR-1 -------MPGADQNGRIDATEGRDDGLQVLRRAAAALDEIATAPGRLRLV
* . :.
Mflv_3087|M.gilvum_PYR-GCK EIAAELGVHKSTVSRLVAVLEARGYVEQVSERGKYRLGFAIPRLAHVAGG
MMAR_4423|M.marinum_M EVADELGVHKSTASRLITALEARGYVEQLSDRGKYQLGIGVSRLARARSG
MSMEG_6757|M.smegmatis_MC2_155 QIAGALGLAKGTAHGLLRTLHGVGFVEQDAS-GRYRLGPDLFHLGSTQLD
Mb3013|M.bovis_AF2122/97 ELCDRTDLPRATAYRLAAALEVHRLLGRGQD-GHWRLGPAITELATHVDD
Rv2989|M.tuberculosis_H37Rv ELCDRTDLPRATAYRLAAALEVHRLLGRGQD-GHWRLGPAITELATHVDD
MAV_3839|M.avium_104 ELCERTELPRATAYRLAAALEVHRLLARGDD-GRWRLGPAVTELAAHVND
MUL_1967|M.ulcerans_Agy99 ELCERTGLPRATAYRLAAALEVHRLLGRDED-GRWGLGPAITELAAHVDD
TH_2042|M.thermoresistible__bu ELCERTGLPRATAHRLAAGLEVHRLLARDGD-GRWCLGPAVTELAARVDD
MAB_3295|M.abscessus_ATCC_1997 ELCERTGLPRATAHRLAAGLEVHRLLSRDGD-GQWQLGAGLTELAAHVND
Mvan_0155|M.vanbaalenii_PYR-1 DVGTNLGLAKSTARRLLVALVDVGFAAVDDS-GRYHLGDRLLGLTSADGS
:: : :.*. * * . *:: ** : * .
Mflv_3087|M.gilvum_PYR-GCK QNDLVKLGQAACDMLSAGVGETANLAVLDADRIVNIVEAIGPSEITLRTW
MMAR_4423|M.marinum_M HSDLVKLSQDACDKLAADLGETANLAILDENRAVNIVEAVSTAEIALQTW
MSMEG_6757|M.smegmatis_MC2_155 LNELKARALNWADALAARTGEAVRVAAFRAGRAVVAHHVFRADATAQVLE
Mb3013|M.bovis_AF2122/97 P--LLVACAAVLPQLRDATGESVQVYRREGTSRVCVAALEPAAGLRDTVP
Rv2989|M.tuberculosis_H37Rv P--LLVACAAVLPQLRDATGESVQVYRREGTSRVCVAALEPAAGLRDTVP
MAV_3839|M.avium_104 P--LLAAGSAVLPLLRETTGESVQLYRREGTDRVCVAALEPAAGLRDTVP
MUL_1967|M.ulcerans_Agy99 P--LLTAGATVLPRLCETTGESVQLYRREGTSRVCVAALEPPAGLRDTVP
TH_2042|M.thermoresistible__bu P--LLAAAAVVLPRLREITGESVQLYRREGTSRICVAALEPPAGLRDTVP
MAB_3295|M.abscessus_ATCC_1997 P--LLSASAQVLPKLREITGESVQLYRREGTVRICVAALEPPAGLRDTVP
Mvan_0155|M.vanbaalenii_PYR-1 T--LAARLRPVIERLALATGETVDLSVLRGRQMWFVDQIESAHRLRAVSA
* * **:. : .
Mflv_3087|M.gilvum_PYR-GCK VGQSCPAYATSSGKVLLAGLDPAELPARIRPPLTEFTDSTLCGLAELQDE
MMAR_4423|M.marinum_M VGQSCPVHATSSGKVLLAGLDADEVRQRVGATLDSFTENTIVTIDALEAQ
MSMEG_6757|M.smegmatis_MC2_155 VGAIVPLHASALGKVLLA---FDPGAARSLGALDSLTYRTITNRAQLQHE
Mb3013|M.bovis_AF2122/97 VGARLPMTAGSGAKVLLAHTDAATQAA------------VLPKAVFSARA
Rv2989|M.tuberculosis_H37Rv VGARLPMTAGSGAKVLLAHTDAATQAA------------VLPKAVFSARA
MAV_3839|M.avium_104 VGARLPMTAGSGAKVLLAHSDAATQKA------------VLANAKFTERT
MUL_1967|M.ulcerans_Agy99 VGARLPMTAGSGAKVLLAHSDPATQQA------------VLPTAKFTDRV
TH_2042|M.thermoresistible__bu VGTRLPMTAGSGAKVLLAYADSTTQQA------------VLSNAKFSERA
MAB_3295|M.abscessus_ATCC_1997 VGSRLPMSAGSGAKVLLAHSDPGTQAA------------VLPGATFTERA
Mvan_0155|M.vanbaalenii_PYR-1 VGGRFPLHDTANGKAALALMEDDAIPDG------------------LLDE
** * : .*. **
Mflv_3087|M.gilvum_PYR-GCK LAAVRERGWACVREELEVGLNAVAAPVYDVHAQVIAALSVSGPSYRLA--
MMAR_4423|M.marinum_M LAATRAAGWASAREELEIGLNAVAAPVYDSTGRVAAALSVSGPAYRLP--
MSMEG_6757|M.smegmatis_MC2_155 LADTRDRGWAASVEEEQPGVASIAAPVRDRGGYVVASIGISGDVERLCDH
Mb3013|M.bovis_AF2122/97 LAEVCRRGWAQSVAEREPGVASVSAPVRDGRGVVIAAISVSGPIDRMG--
Rv2989|M.tuberculosis_H37Rv LAEVCRRGWAQSVAEREPGVASVSAPVRDGRGVVIAAISVSGPIDRMG--
MAV_3839|M.avium_104 LAEVRRRGWAQSVAEREPGVASVSAPVRDSRGAVIAAISVSGPIDRIG--
MUL_1967|M.ulcerans_Agy99 LAEVRRRGWAQSVAEREPGVASVSAPVRDGRGVVVAAISVSGPIDRIG--
TH_2042|M.thermoresistible__bu LAEVHKRGWAQSVAEREPGVASVSAPVRDGRGTVVAAVSVSGPIDRIG--
MAB_3295|M.abscessus_ATCC_1997 LADVRKRGWAQSAAEREAGVASVSAPVRDRHGNVIAAISVSGPIDRMG--
Mvan_0155|M.vanbaalenii_PYR-1 IAEVRRTGIAYDRDEHTAGISAAGIAVR-LPGGHVVAISVPAPTERFR--
:* . * * * *: : . .* . .::.:.. *:
Mflv_3087|M.gilvum_PYR-GCK -VDRFDEVAKQTVAAAEQISRRLGWTTRN-
MMAR_4423|M.marinum_M -AADFEEVAQQTIAAADAVSRGLGWTDRIS
MSMEG_6757|M.smegmatis_MC2_155 RARPLERLAELVVRAGRSVSREFGHGREL-
Mb3013|M.bovis_AF2122/97 -RRPGVRWAADLLSAADALTRRL-------
Rv2989|M.tuberculosis_H37Rv -RRPGVRWAADLLSAADALTRRL-------
MAV_3839|M.avium_104 -RRPGARWAADLVSAAEALTRRL-------
MUL_1967|M.ulcerans_Agy99 -RRPGARWAADLLAAADELARRL-------
TH_2042|M.thermoresistible__bu -RRPGARWAADLLAAAEALTRRL-------
MAB_3295|M.abscessus_ATCC_1997 -RRPGARWAADLVAASEAITARL-------
Mvan_0155|M.vanbaalenii_PYR-1 -AQESTIVDALRAAAADPVWAGGVS-----
*. :