For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
RRRGRPAGGGNTPEQARRLLVQTAERCFAENGLDITMAEVAKRAGVSRAVLYRHFGGRDELVVAVAVQVM DRYVARVVDDLIPTDDVAALITESLVFVTTVVSRDPLLELLSMGAEHGVASLLANSPVLCGKVAGLYEQV FVLFRDRLRVGLEPGDVGRYILGVALSLLMNVIPGSDDPATVRRYVRTFVLPAIVASPPDAVSVFV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4418 | - | - | 100% (207) | transcriptional regulatory protein |
| M. marinum M | MMAR_3161 | - | 8e-15 | 27.27% (187) | transcriptional regulatory protein |
| M. marinum M | MMAR_0226 | - | 6e-12 | 34.23% (111) | hypothetical protein MMAR_0226 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1711c | - | 9e-07 | 40.00% (65) | hypothetical protein Mb1711c |
| M. gilvum PYR-GCK | Mflv_0366 | - | 3e-38 | 43.72% (215) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1255c | - | 5e-08 | 28.19% (188) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_01733 | - | 3e-06 | 24.47% (94) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0530 | - | 1e-43 | 44.71% (208) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4189 | - | 3e-13 | 26.15% (195) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5854 | - | 8e-10 | 26.50% (200) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_4364 | - | 2e-12 | 39.45% (109) | PUTATIVE transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_4487 | - | 2e-08 | 29.32% (191) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0369 | - | 2e-27 | 38.02% (192) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0366|M.gilvum_PYR-GCK -----------------------MAEADSEPFAPSASGRSTSPARRRGRP
Mvan_0369|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_0530|M.abscessus_ATCC_1997 -------------------------------MARKAQGEDKAP-RGRGRP
MMAR_4418|M.marinum_M -------------------------------------------MRRRGRP
MAV_4189|M.avium_104 -------------------------------------------MRTHGWQ
TH_4364|M.thermoresistible__bu -------------------------------------------MRTHGWR
MSMEG_5854|M.smegmatis_MC2_155 -------------------------------------------MRTHGWS
Rv1255c|M.tuberculosis_H37Rv -------------------------------------------MAGTDWL
MUL_4487|M.ulcerans_Agy99 -------------------------------------------MGRTDWL
Mb1711c|M.bovis_AF2122/97 ----------------------------------------MAAPDNSRRR
MLBr_01733|M.leprae_Br4923 MTRRSIHTRKPLKWSGCAGQHVRSGKVFDVGRISLSYPSMKPGVKIDARS
Mflv_0366|M.gilvum_PYR-GCK VGGGNTSDQARTVLMDAAERSILRRGFQASTMELVAREAGYSRAAIYRHF
Mvan_0369|M.vanbaalenii_PYR-1 --------------MDAAERSILQRGFQASTMELIAREAGYSRAAMYRQF
MAB_0530|M.abscessus_ATCC_1997 PGGGNTAQQAQEQLLDAAERLFIARGYAASTMEAIAREAGYSRAVVYRHF
MMAR_4418|M.marinum_M AGGGNTPEQARRLLVQTAERCFAENGLDI-TMAEVAKRAGVSRAVLYRHF
MAV_4189|M.avium_104 GEPPRSDEDAVARIVAAADRCVRRRG-GQTTIADVAAELGVSRKTVYRYF
TH_4364|M.thermoresistible__bu GTPPRSDDEAVERILAATHRCVAERG-GQTTIAHVAAELGVSRATVYRYF
MSMEG_5854|M.smegmatis_MC2_155 GSAPATDEEAIARILAAAGKAIDERG-ADFSIADVARTLGVTRQTVYRYF
Rv1255c|M.tuberculosis_H37Rv S--ARRTELAADRILDAAERLFTQRDPASIGMNEIAKAAGCSRATLYRYF
MUL_4487|M.ulcerans_Agy99 A--AHRSEVAADRILDAAERLYTEHDPASIGMNEIARAAGCSRATLYRYF
Mb1711c|M.bovis_AF2122/97 PGRPAGSSDTRERILSSARELFAHNGIDRTSIRAVAAKAGVDAALVHHYF
MLBr_01733|M.leprae_Br4923 ERWREHRKKVRGEIVDAAFRALDRLG-PEVSVREIAEEAGTAKPKIYRHF
: :: . . : :* * ::: *
Mflv_0366|M.gilvum_PYR-GCK PSRRLLLEALVERKTRRHQTEISARLTENASLA-DLLTEGLVIVATELIH
Mvan_0369|M.vanbaalenii_PYR-1 PSRQHLLEALVARKTRRHQIEIVSRMPENADLA-EILVEGLVIVATELVH
MAB_0530|M.abscessus_ATCC_1997 RNRDDLMDALVVRATMNEITNMIGRLMALKSLA-EIIPESLVIVSVEVGA
MMAR_4418|M.marinum_M GGRDELVVAVAVQVMDRYVARVVDDLIPTDDVA-ALITESLVFVTTVVSR
MAV_4189|M.avium_104 PSTTALLRAVATEGTRKFLEAMAERLSAIDDIA-EAVVEGVVLTVTAVPD
TH_4364|M.thermoresistible__bu PSTSALLQAAAVEGTRRFLHRMAERLGRIDDVA-DAIIEGVVQTVAAVPN
MSMEG_5854|M.smegmatis_MC2_155 PSTDALLVAAAVHAASGFLDRLAAHLSGITDPV-EAVTEAIATALEWVPQ
Rv1255c|M.tuberculosis_H37Rv DSREALRTAYVHRETRRLGREIMVKIADVVEPA-ERLLVSITTTLRMVRD
MUL_4487|M.ulcerans_Agy99 ESREALRTAYVHRETLRLGREIMQQIGDIDDPR-DQLITSITATLRMVRQ
Mb1711c|M.bovis_AF2122/97 GTKQQLFAAAIHIPIDPMVIIGPIREAPVEELG-YKLPSLLLPIWDSELG
MLBr_01733|M.leprae_Br4923 TDKSDLFEAIGIRLRDMLWAAIFPAIDLATDSAREIIRRSVDEYVSLVDK
* * . : :
Mflv_0366|M.gilvum_PYR-GCK DP-LLRTLSEQ--TDEGTVAHLVAGAARIPEQVEQLIAATDGGESEKIFR
Mvan_0369|M.vanbaalenii_PYR-1 DP-LLQTLSEQ--TDEGTVAHLVAGAARLPELVEQLFEAMDDGEAGPTFR
MAB_0530|M.abscessus_ATCC_1997 NP-LLRVLADR--DDRGTVASLIVDAPNLIDLLTAMYAGVFS-TRMAEVR
MMAR_4418|M.marinum_M DP-LLELLSMG--AEHG-VASLLANSPVLCGKVAGLYEQVFVLFRDR-LR
MAV_4189|M.avium_104 EP-YLQLLLEE-PSHALLRSITSETARRVGQQVLVEHTSVDWERTPMASR
TH_4364|M.thermoresistible__bu EP-YLRLLLDE-PSHVLLRDVTSESAREIGKSMLLESTSVDWARLRPAAE
MSMEG_5854|M.smegmatis_MC2_155 DK-HLGLLISPGRADAHTESVTSDVAVDFARAMLRKFD-VDWAGLGFGDD
Rv1255c|M.tuberculosis_H37Rv NP-ALAAWFTT-----TRPPIGGEMAGRS--EVIAALAAAFLNSLGPDDP
MUL_4487|M.ulcerans_Agy99 RP-ALAAWFAS-----TRPPIGGELAGQS--EVIAGLAAAFLQSLGPEAP
Mb1711c|M.bovis_AF2122/97 AG-LIATLRSL------ISGSDVGLARSFLEEVVTVELGSRVDNPPGTGK
MLBr_01733|M.leprae_Br4923 HPNVLRVFIQGRFSAQSEATVRTLDEGREITLTMAEMFNNELREMELNRA
:
Mflv_0366|M.gilvum_PYR-GCK PGVEAGDVGQFLITAALTMLLGVIPGIEDPETARRYVRTFVLPAILADPP
Mvan_0369|M.vanbaalenii_PYR-1 PGLRADDVGQFLVTTSLTMLLGVIPGIADSETARRYVQTFVLPAILADPP
MAB_0530|M.abscessus_ATCC_1997 QGVRPEDAARYVLSVALSLLLGLIPGTDDPEQVRRYVRVFVLPTLLADPP
MMAR_4418|M.marinum_M VGLEPGDVGRYILGVALSLLMNVIPGSDDPATVRRYVRTFVLPAIVASPP
MAV_4189|M.avium_104 ---TLDELVEWSLRAVHSFLANPSDPPRDADQLRGYLRRWLAPAIRQWVQ
TH_4364|M.thermoresistible__bu IVDELDELIEWSLRIVQSFLTDPGDPPRSPDALRAHLHRWLGPAIREWVA
MSMEG_5854|M.smegmatis_MC2_155 ---DLDELAEHLLRIIQSFIIDPGRPPRTGATLRSYLRRWVGAAVKPAQA
Rv1255c|M.tuberculosis_H37Rv --TTVERRARWVVRMLTSLLMFPG---RDEADERAMIAEFVVPIVTPASA
MUL_4487|M.ulcerans_Agy99 --AAVERRARWTVRVIVSLLMFPG---QDEADERAMLEEFVAPVVTPFPT
Mb1711c|M.bovis_AF2122/97 IRTQFVASQLMGVVMARYIVRIEPFASLPAEQIVQTIAPNLQRYLTGELP
MLBr_01733|M.leprae_Br4923 ASELAAFAAFGSVASATEWWLGPEPDSPRRMPREQFVAHLTIIMMAVIVG
: : :
Mflv_0366|M.gilvum_PYR-GCK APQQVFRPR-----------------
Mvan_0369|M.vanbaalenii_PYR-1 APREVFGS------------------
MAB_0530|M.abscessus_ATCC_1997 QPEAVFI-------------------
MMAR_4418|M.marinum_M DAVSVFV-------------------
MAV_4189|M.avium_104 QAAAGTMV------------------
TH_4364|M.thermoresistible__bu SVGIDAEQSPPE--------------
MSMEG_5854|M.smegmatis_MC2_155 SVQSPRV-------------------
Rv1255c|M.tuberculosis_H37Rv AARKAGHPGPE---------------
MUL_4487|M.ulcerans_Agy99 RR------------------------
Mb1711c|M.bovis_AF2122/97 DDLAP---------------------
MLBr_01733|M.leprae_Br4923 TAETLGISMNPDRPIHDAVPLDRSAS