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MRTHGWQGEPPRSDEDAVARIVAAADRCVRRRGGQTTIADVAAELGVSRKTVYRYFPSTTALLRAVATEG TRKFLEAMAERLSAIDDIAEAVVEGVVLTVTAVPDEPYLQLLLEEPSHALLRSITSETARRVGQQVLVEH TSVDWERTPMASRTLDELVEWSLRAVHSFLANPSDPPRDADQLRGYLRRWLAPAIRQWVQQAAAGTMV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4189 | - | - | 100% (208) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_2960 | - | 4e-39 | 43.37% (196) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_1115 | - | 5e-38 | 41.62% (197) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2274c | - | 5e-07 | 31.20% (125) | transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1606 | - | 2e-39 | 42.05% (195) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1255c | - | 2e-06 | 31.31% (99) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_02457 | - | 6e-06 | 25.15% (171) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4765 | - | 1e-38 | 41.54% (195) | putative regulatory protein TetR |
| M. marinum M | MMAR_0226 | - | 5e-34 | 39.80% (196) | hypothetical protein MMAR_0226 |
| M. smegmatis MC2 155 | MSMEG_5854 | - | 1e-40 | 44.67% (197) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_4364 | - | 2e-77 | 67.82% (202) | PUTATIVE transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_4888 | - | 3e-27 | 36.70% (188) | hypothetical protein MUL_4888 |
| M. vanbaalenii PYR-1 | Mvan_5152 | - | 4e-42 | 44.62% (195) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_4189|M.avium_104 ---------MRTHGWQGEPPRSDEDAVARIVAAADRCVRRRG-GQTTIAD
TH_4364|M.thermoresistible__bu ---------MRTHGWRGTPPRSDDEAVERILAATHRCVAERG-GQTTIAH
Mflv_1606|M.gilvum_PYR-GCK ---MAYSAFVRTHGWSGAKPASDDEAVARILEAAGKAIEERG-ADFSISD
Mvan_5152|M.vanbaalenii_PYR-1 MTGLAYSSLVRTHGWSGAKPASDEEAVARILAAAGKVIEERG-ADFSISD
MSMEG_5854|M.smegmatis_MC2_155 ---------MRTHGWSGSAPATDEEAIARILAAAGKAIDERG-ADFSIAD
MMAR_0226|M.marinum_M --------MARRRGWNGAPPASDEEASRRIVDTAVRLIAETG-SDVSLAQ
MUL_4888|M.ulcerans_Agy99 --------MVSRPKRRGVSRIG------RGVRRHRRGIAETG-SDVSLAQ
MAB_4765|M.abscessus_ATCC_1997 --------MARRRGWDGQPPSSDEEAAERIVAAAVKLIGETG-SAVSLAD
Rv1255c|M.tuberculosis_H37Rv ---------MAGTDWLS--ARRTELAADRILDAAERLFTQRDPASIGMNE
Mb2274c|M.bovis_AF2122/97 ---------------MLSMSNDRADTGGRILRAAASCVVDYGVDRVTLAE
MLBr_02457|M.leprae_Br4923 MAEHIPAVAVKTDGRKRRWHQHKVERRNELVDGTIDAIRRQG-RFLSMDE
. : . . : .
MAV_4189|M.avium_104 VAAELGVSRKTVYRYFPSTTALLRAVATEGTRK-FLEAMAERLSAIDDIA
TH_4364|M.thermoresistible__bu VAAELGVSRATVYRYFPSTSALLQAAAVEGTRR-FLHRMAERLGRIDDVA
Mflv_1606|M.gilvum_PYR-GCK VARTVGVTRQTVYRYFSSTEALLVAAAVHAVDG-FLDRLAAHLVGVTDPP
Mvan_5152|M.vanbaalenii_PYR-1 VARTVGVTRQTVYRYFPSTEALLVAAAVHAVDG-FLERLTAHMAGITDPA
MSMEG_5854|M.smegmatis_MC2_155 VARTLGVTRQTVYRYFPSTDALLVAAAVHAASG-FLDRLAAHLSGITDPV
MMAR_0226|M.marinum_M VAASLGVIRQTVYRYYPTADALMRAAAIASVDG-FLDRLTEAVRGMRDPA
MUL_4888|M.ulcerans_Agy99 VAASLGVIRQTVYRYYPTADALMRAAAIASVDG-FLDRLTEAVRGMRDPA
MAB_4765|M.abscessus_ATCC_1997 VAAELGVIRQTVYRYFPTADALMHAASLASVDG-FLDRLTHVVRGITDPA
Rv1255c|M.tuberculosis_H37Rv IAKAAGCSRATLYRYFDSREALRTAYVHRETRR-LGREIMVKIADVVEPA
Mb2274c|M.bovis_AF2122/97 IARRAGVSRPTVYRRWPDTRSIMASMLTSHIAA-VLREVPLDG----DDR
MLBr_02457|M.leprae_Br4923 IAGKIGVSKTVLYRYFIDKNDLTTAVMMRFAQTTLIPNMAAALSTNLDGF
:* * : .:** : : : . : :
MAV_4189|M.avium_104 EAVVEGVVLTVTAVPDEPYLQLLLE-EPSHALLRSITSETARRVGQQVLV
TH_4364|M.thermoresistible__bu DAIIEGVVQTVAAVPNEPYLRLLLD-EPSHVLLRDVTSESAREIGKSMLL
Mflv_1606|M.gilvum_PYR-GCK EAVTEAVATALEWLPREKYIGLIMAPGGS-THVQSVTSDIALRFARDMVG
Mvan_5152|M.vanbaalenii_PYR-1 EAVTEAVATALEWLPREKYIGLIMVPGRS-THVQSVTSDIALRFGRDMVG
MSMEG_5854|M.smegmatis_MC2_155 EAVTEAIATALEWVPQDKHLGLLISPGRADAHTESVTSDVAVDFARAMLR
MMAR_0226|M.marinum_M EAMAEAVMFTLRDVVRTPHLGILIAQPYAHTHPENLTSEEAQVFGVRMLE
MUL_4888|M.ulcerans_Agy99 EAMAEAVMFTLRDVVRTPHLGILIAQPYAHTHPENLTSEEAQVFGVRMLE
MAB_4765|M.abscessus_ATCC_1997 EALTEGVLYTLEEVTRTPHLGIMMSEPYAHSHTSDMTSDEAQAFGLRMLD
Rv1255c|M.tuberculosis_H37Rv ERLLVSITTTLRMVRDNPALAAWFTTTRPPIGGEMAGRSEVIAALAAAFL
Mb2274c|M.bovis_AF2122/97 EALVKQIVAVADRLRGDDLIMSVMHSELARVYITERLGTSQQVLIEGLAA
MLBr_02457|M.leprae_Br4923 DLTREIIRVYVKTVAAEPEPYQFVMANSSASKSKVIADSERIIARMLAVM
: : : . .
MAV_4189|M.avium_104 EHTSVDWERTPMASR---TLDELVEWSLRAVHSFLANPSDPPRDADQLRG
TH_4364|M.thermoresistible__bu ESTSVDWARLRPAAEIVDELDELIEWSLRIVQSFLTDPGDPPRSPDALRA
Mflv_1606|M.gilvum_PYR-GCK R-LDVDWTAAGF-DEA--ELDQLSEHLLRIIQSFVLDPGRPPRRGDELRS
Mvan_5152|M.vanbaalenii_PYR-1 R-LDVDWAAAGF-DDA--DLDQLSEHLLRIIQSFVVDPGRPPRHGEQLRT
MSMEG_5854|M.smegmatis_MC2_155 K-FDVDWAGLGF-GDD--DLDELAEHLLRIIQSFIIDPGRPPRTGATLRS
MMAR_0226|M.marinum_M R-FDVDWAEYGFADES--ARHDLVEFLLRVLLSFFVAPNVPSRSDDELKS
MUL_4888|M.ulcerans_Agy99 R-FDVDWAEYGFADES--ARHDLVEFLLRVLLSFFVAPNVPSRSDDELKS
MAB_4765|M.abscessus_ATCC_1997 R-FDVDWVQYGY-DDA--AKRELVEFALRIMLSFFVSPNEATRSRDELRG
Rv1255c|M.tuberculosis_H37Rv N-------SLGPDDPT--TVERRARWVVRMLTSLLMFPG---RDEADERA
Mb2274c|M.bovis_AF2122/97 R-LTVAQRSGSVRSGD---ARRLATMVLLIAQSTIQSADIVDSILD--SA
MLBr_02457|M.leprae_Br4923 IRRRMQEAGMDAGGVEP-WAYLIVGGVQLATHSWMSDPRMSADELIDYLT
* . .
MAV_4189|M.avium_104 YLRR-------WLAPAIRQWVQQAAAGTMV-----
TH_4364|M.thermoresistible__bu HLHR-------WLGPAIREWVASVGIDAEQSPPE-
Mflv_1606|M.gilvum_PYR-GCK YLRR-------WVGNALLRR---------------
Mvan_5152|M.vanbaalenii_PYR-1 YLRR-------WVGNALPLR---------------
MSMEG_5854|M.smegmatis_MC2_155 YLRR-------WVGAAVKPAQASVQSPRV------
MMAR_0226|M.marinum_M FIKR-------WVGGAILAQKR-------------
MUL_4888|M.ulcerans_Agy99 FIRR-------WVGGAIVAQKR-------------
MAB_4765|M.abscessus_ATCC_1997 FLKR-------WLGGAVLAQGR-------------
Rv1255c|M.tuberculosis_H37Rv MIAE-------FVVPIVTPASAAARKAGHPGPE--
Mb2274c|M.bovis_AF2122/97 ALAT-------ELTHALNGYLC-------------
MLBr_02457|M.leprae_Br4923 MLSWNALCGIVEVGGSLEKFRKQPHPSPIIPPRGP
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