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MAEADSEPFAPSASGRSTSPARRRGRPVGGGNTSDQARTVLMDAAERSILRRGFQASTMELVAREAGYSR AAIYRHFPSRRLLLEALVERKTRRHQTEISARLTENASLADLLTEGLVIVATELIHDPLLRTLSEQTDEG TVAHLVAGAARIPEQVEQLIAATDGGESEKIFRPGVEAGDVGQFLITAALTMLLGVIPGIEDPETARRYV RTFVLPAILADPPAPQQVFRPR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0366 | - | - | 100% (232) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3024 | - | 2e-19 | 29.03% (186) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4624 | - | 3e-17 | 27.96% (186) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2534 | - | 2e-07 | 32.39% (142) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1255c | - | 3e-08 | 39.29% (84) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0530 | - | 2e-52 | 49.55% (222) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4418 | - | 4e-38 | 43.72% (215) | transcriptional regulatory protein |
| M. avium 104 | MAV_3154 | - | 2e-14 | 30.00% (180) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_4953 | - | 1e-10 | 27.04% (196) | putative transcriptional regulator |
| M. thermoresistible (build 8) | TH_4364 | - | 2e-12 | 28.64% (199) | PUTATIVE transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_3785 | - | 1e-07 | 27.15% (221) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0369 | - | 2e-80 | 79.26% (188) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0366|M.gilvum_PYR-GCK MAEADSEPFAPSASGRSTSPARRRGRP---VGGGNTSDQARTVLMDAAER
Mvan_0369|M.vanbaalenii_PYR-1 --------------------------------------------MDAAER
MAB_0530|M.abscessus_ATCC_1997 --------MARKAQGEDKAP-RGRGRP---PGGGNTAQQAQEQLLDAAER
MMAR_4418|M.marinum_M --------------------MRRRGRP---AGGGNTPEQARRLLVQTAER
Mb2534|M.bovis_AF2122/97 --------------MTASAPDGRPGQPEATNRRSQLKSDRRFQLLAAAER
MUL_3785|M.ulcerans_Agy99 --------------MAASAPDEQTATP---NRRSQQKSDRRLQLLSAAER
TH_4364|M.thermoresistible__bu -----------------MRTHGWRGTP------PRSDDEAVERILAATHR
MSMEG_4953|M.smegmatis_MC2_155 ------------------------------MTNATAPRSVRDRLIDAAET
Rv1255c|M.tuberculosis_H37Rv ----------------------MAGTD---WLSARRTELAADRILDAAER
MAV_3154|M.avium_104 ----------------MPAARRRRGRP---AGSRVDPDERRTALLDAAER
: ::.
Mflv_0366|M.gilvum_PYR-GCK SILRRGFQASTMELVAREAGYSRAAIYRHFPSRRLLLEALVERKTRRHQT
Mvan_0369|M.vanbaalenii_PYR-1 SILQRGFQASTMELIAREAGYSRAAMYRQFPSRQHLLEALVARKTRRHQI
MAB_0530|M.abscessus_ATCC_1997 LFIARGYAASTMEAIAREAGYSRAVVYRHFRNRDDLMDALVVRATMNEIT
MMAR_4418|M.marinum_M CFAENGLDI-TMAEVAKRAGVSRAVLYRHFGGRDELVVAVAVQVMDRYVA
Mb2534|M.bovis_AF2122/97 LFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVELLVGVSARLLA
MUL_3785|M.ulcerans_Agy99 LFAERGFLAVRLEDIGAAAGISGPAIYRHFPNKESLLVELLVGISSRLLA
TH_4364|M.thermoresistible__bu CVAERGGQT-TIAHVAAELGVSRATVYRYFPSTSALLQAAAVEGTRRFLH
MSMEG_4953|M.smegmatis_MC2_155 CLRAKGIRATTVSEVAEAAGVSRGWLYRHFPDKVSLLGAAIVRLNDAYWS
Rv1255c|M.tuberculosis_H37Rv LFTQRDPASIGMNEIAKAAGCSRATLYRYFDSREALRTAYVHRETRRLGR
MAV_3154|M.avium_104 AIRAKGPSA-GLVDIAGEAGFVRSAVYAMYPGRDALLAELSRRTAQRLLG
. .. : :. * :* : . *
Mflv_0366|M.gilvum_PYR-GCK EISARLTENASLADLLTEGLVIVATELIH-DPLLRTLSEQTDEGTVAHLV
Mvan_0369|M.vanbaalenii_PYR-1 EIVSRMPENADLAEILVEGLVIVATELVH-DPLLQTLSEQTDEGTVAHLV
MAB_0530|M.abscessus_ATCC_1997 NMIGRLMALKSLAEIIPESLVIVSVEVGA-NPLLRVLADRDDRGTVASLI
MMAR_4418|M.marinum_M RVVDDLIPTDDVAALITESLVFVTTVVSR-DPLLELLSMGAEHG-VASLL
Mb2534|M.bovis_AF2122/97 GARDVTTRSANLAAALDGLIEFHLDFALG-EADLIRIQDR----DLAHLP
MUL_3785|M.ulcerans_Agy99 GARQVTTNSNDAAAALDGLIDFHLDFALG-EPDLIRIQDR----DLGHLP
TH_4364|M.thermoresistible__bu RMAERLGRIDDVADAIIEGVVQTVAAVPN-EPYLRLLLDEPSHVLLRDVT
MSMEG_4953|M.smegmatis_MC2_155 DAHAFLAAYDGLDEKIAAGIRYGRTAYDDPGALLMKLRLDEPEEFAACAG
Rv1255c|M.tuberculosis_H37Rv EIMVKIADVVEPAERLLVSITTTLRMVRD-NPALAAWFTTTRPPIGGEMA
MAV_3154|M.avium_104 EITTRAAGSTDLRQRMALFFDVISAWMQAEPNLYRALTGEPSTSVFEQLA
: .
Mflv_0366|M.gilvum_PYR-GCK AGAARIPEQVEQLIAATDGGESEKIFRPGVEA-GDVGQFLITAALTMLLG
Mvan_0369|M.vanbaalenii_PYR-1 AGAARLPELVEQLFEAMDDGEAGPTFRPGLRA-DDVGQFLVTTSLTMLLG
MAB_0530|M.abscessus_ATCC_1997 VDAPNLIDLLTAMYAGVFS-TRMAEVRQGVRP-EDAARYVLSVALSLLLG
MMAR_4418|M.marinum_M ANSPVLCGKVAGLYEQVFVLFRDR-LRVGLEP-GDVGRYILGVALSLLMN
Mb2534|M.bovis_AF2122/97 AVAERQVRKAQRQYVEVWVGVLRE-LNPGLAE-ADAR--LMAHAVFGLLN
MUL_3785|M.ulcerans_Agy99 AAAERQVRKAQRQYVEIWVGVLRQ-LDPGLAE-ADAR--LMAHAAFGLLN
TH_4364|M.thermoresistible__bu SESAREIGKSMLLESTSVDWARLRPAAEIVDELDELIEWSLRIVQSFLTD
MSMEG_4953|M.smegmatis_MC2_155 AGVQGLVPDLAAFWTRYLLAARDTGEIHPNTDIAEAAEWVARVVISFATV
Rv1255c|M.tuberculosis_H37Rv GRSEVIAALAAAFLNSLGP--------DDPTTVERRARWVVRMLTSLLMF
MAV_3154|M.avium_104 GAVEQMLTTSSGSEQARRAAAPWS--RAIVGSAVSAAEWWCRAGTMPRAE
Mflv_0366|M.gilvum_PYR-GCK VIPGIEDPET--ARRYVRTFVLPAILADPPAPQQVFRPR---
Mvan_0369|M.vanbaalenii_PYR-1 VIPGIADSET--ARRYVQTFVLPAILADPPAPREVFGS----
MAB_0530|M.abscessus_ATCC_1997 LIPGTDDPEQ--VRRYVRVFVLPTLLADPPQPEAVFI-----
MMAR_4418|M.marinum_M VIPGSDDPAT--VRRYVRTFVLPAIVASPPDAVSVFV-----
Mb2534|M.bovis_AF2122/97 STPHSMKAAD--SKPARTVRARAVLRAMTVAALSAADRCL--
MUL_3785|M.ulcerans_Agy99 STPHSMESAD--TKSACAPHSRAVMRAMTVAALTVDVGA---
TH_4364|M.thermoresistible__bu PGDPPRSPDA--LRAHLHRWLGPAIREWVASVGIDAEQSPPE
MSMEG_4953|M.smegmatis_MC2_155 PGEQLDASDTGAVLTHLRRYVMPGLRAEPAS-----------
Rv1255c|M.tuberculosis_H37Rv PGRDEADE-----RAMIAEFVVPIVTPASAAARKAGHPGPE-
MAV_3154|M.avium_104 LVEHLTALCWD--GGAALPFNADDIRTIDSGPH---------
: