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MTAPGGSFDEGAHDGAASPPPGEQPSEQPFSPPPDAPWAAPEAASPADDYPAPSYPPPAYPPEPVGPGGY PPDYATGYPPPPGYPPPGYPPYGAAAGEYGGTPYPPPPPPPAPMAAPYGAPPPNYPPPSYPGGYYPPPDP MAGYGPALPGMNTMAIVALVSSLVGVFCCIGSVVAIVVGTIAINQIKQTREDGYGLAVAGIVIAVATLLI YLVVGIFSIPSH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4208 | - | - | 100% (222) | proline and glycine rich transmembrane protein |
| M. marinum M | MMAR_2166 | - | 2e-20 | 35.68% (227) | proline and glycine rich transmembrane protein |
| M. marinum M | MMAR_4389 | pra | 7e-20 | 49.15% (118) | proline-rich antigen, Pra |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1265c | - | 4e-70 | 58.93% (224) | hypothetical protein Mb1265c |
| M. gilvum PYR-GCK | Mflv_2210 | - | 1e-26 | 39.56% (225) | hypothetical protein Mflv_2210 |
| M. tuberculosis H37Rv | Rv1233c | - | 2e-70 | 58.93% (224) | hypothetical protein Rv1233c |
| M. leprae Br4923 | MLBr_02395 | Ag36 | 1e-15 | 44.66% (103) | proline rich antigenic protein |
| M. abscessus ATCC 19977 | MAB_1370c | - | 8e-27 | 34.62% (234) | hypothetical protein MAB_1370c |
| M. avium 104 | MAV_1372 | - | 1e-48 | 46.98% (232) | hypothetical protein MAV_1372 |
| M. smegmatis MC2 155 | MSMEG_5268 | - | 8e-24 | 34.78% (230) | hypothetical protein MSMEG_5268 |
| M. thermoresistible (build 8) | TH_3105 | - | 3e-26 | 35.02% (257) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_1750 | - | 9e-19 | 35.24% (210) | proline and glycine rich transmembrane protein |
| M. vanbaalenii PYR-1 | Mvan_4486 | - | 8e-43 | 48.85% (217) | hypothetical protein Mvan_4486 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1265c|M.bovis_AF2122/97 ---MTAPSGSSG-------------------------------ESAHDAA
Rv1233c|M.tuberculosis_H37Rv ---MTAPSGSSG-------------------------------ESAHDAA
MMAR_4208|M.marinum_M ---MTAPGGSFD-------------------------------EGAHDGA
MAV_1372|M.avium_104 MNTMTAPGAGFG-------------------------------ESAQHDH
Mflv_2210|M.gilvum_PYR-GCK ---MTSSDNDADR-----------------------------VESSESAA
Mvan_4486|M.vanbaalenii_PYR-1 ---MTSSDNDAGR-----------------------------GESSDSTA
TH_3105|M.thermoresistible__bu ---MTNPGNADGTPPAEGQPGPSETGADDLAREPTGGADPTASEHTPDQP
MAB_1370c|M.abscessus_ATCC_199 ---MTTPGHEPSG------------------------------SSPDASS
MSMEG_5268|M.smegmatis_MC2_155 ---MTDQP--PGNNPP-------------------------PPDGGYPPP
MUL_1750|M.ulcerans_Agy99 ---MSQPPENPGNQAD-------------------------PQDGDQSTP
MLBr_02395|M.leprae_Br4923 ---MTDQPPPSG---------------------------------SNPTP
*: .
Mb1265c|M.bovis_AF2122/97 GGPPPVGERPPEQPIA---DAPWAPP-ASSPMA---DHPPPAY-PPSG--
Rv1233c|M.tuberculosis_H37Rv GGPPPVGERPPEQPIA---DAPWAPP-ASSPMA---NHPPPAY-PPSG--
MMAR_4208|M.marinum_M ASPPP-GEQPSEQPFSPPPDAPWAAPEAASPAD---DYPAPSY-PPPA--
MAV_1372|M.avium_104 HGDQAHGDKPNDDATS----APHAQPAPWEPPA---GSVPPPY-PPPG--
Mflv_2210|M.gilvum_PYR-GCK DGSEPTPAGYEAPSIEHTPSAPDTSSDDTPPHG---YTPPPAYNPPPSST
Mvan_4486|M.vanbaalenii_PYR-1 SGSEPSSAGYEPPPIEQTQSAPPPAQDYLPPPA---YDAPPAYPPSPG--
TH_3105|M.thermoresistible__bu TAADQAADQAGDRPDEQAFDGSWAAAGETAPAY---GESPPAGFAPLDYP
MAB_1370c|M.abscessus_ATCC_199 GYEYPSLEKSAPPADPAVAANPTPSPPPAWEAP---GQPTASYPAYPAS-
MSMEG_5268|M.smegmatis_MC2_155 ---PPPDGGYPPPPPPDG-GYPPAQPGGFGPPPQGGYPPPPPPGGYPPPP
MUL_1750|M.ulcerans_Agy99 GYPPPPNYGTPPPPPPPGYGAPPAGPPGYGAPP-----PPPGYGTPPPPP
MLBr_02395|M.leprae_Br4923 APPPPGSSGGYEPSFAPSELGSAYPPPTAPPVGGSYPPPPPPGGSYPP--
. . ..
Mb1265c|M.bovis_AF2122/97 ---YPP------AYQPG-----YPTDYPPPMP------------PGGYAP
Rv1233c|M.tuberculosis_H37Rv ---YPP------AYQPG-----YPTGYPPPMP------------PGGYAP
MMAR_4208|M.marinum_M ---YPPEPVGPGGYPPD-----YATGYPP--P------------PG-YPP
MAV_1372|M.avium_104 ---YPA------DYPPG-----YPPPYPPPAPS-----------PVPPPP
Mflv_2210|M.gilvum_PYR-GCK PPMYGTPPN--TGYPAPG--DFTSPPYPPPPAGY---------GAQNYPP
Mvan_4486|M.vanbaalenii_PYR-1 ---YEQQP----GYPPSG--GFAAPDYPPPPAGY---------PPP-YPD
TH_3105|M.thermoresistible__bu GAGAGTEPYQPSGYPAPPPGAQYPPPYPPGPQQP---------GYGYPAP
MAB_1370c|M.abscessus_ATCC_199 ------------AYPTAP------PAYPTAPPP-----------YPTASQ
MSMEG_5268|M.smegmatis_MC2_155 QGGFPPPPPGGYPPPPPPQGGSYPPPPPPGAAGYPPPGYPGGPGAGYPPA
MUL_1750|M.ulcerans_Agy99 PPGYG-QAPGGYAPP------GYNPPPPP------PPGY-GPPPAGYSTQ
MLBr_02395|M.leprae_Br4923 ------------PPPPGG---SYPPPPPSTGAY-----------APPPPG
. *. .
Mb1265c|M.bovis_AF2122/97 PGYPPPGTSSAGYG---DIPY-PPMPPP-------YGGSP----------
Rv1233c|M.tuberculosis_H37Rv PGYPPPGTSSAGYG---DIPY-PPMPPP-------YGGSP----------
MMAR_4208|M.marinum_M PGYPPYGAAAGEYG---GTPY-PPPPPPPAPMAAPYGAPPPNYPPPSY--
MAV_1372|M.avium_104 PGYGPP--PPPGYG---PPGY-PGGYYP---------GPD----------
Mflv_2210|M.gilvum_PYR-GCK PGYGAQGYGAQGYG---PQGYGAQSYGAQG-YPSPYGAYP----------
Mvan_4486|M.vanbaalenii_PYR-1 AGPPPP---HPGYG---APGYGAPSYPPPPPYGTMPGGYPP---------
TH_3105|M.thermoresistible__bu PPYDAPRYPTPPYDPAQPPQFGAGQFGAAGYPDPNQPGYP----------
MAB_1370c|M.abscessus_ATCC_199 AAYPQYGQSYPSYQPGQPGTYPPPGYPVAG----GYPGYPP---------
MSMEG_5268|M.smegmatis_MC2_155 GGFGQPGGYAPVGAPGFGGAYSVGDAFSWAWNKFSKHAVEMIVPALVFGL
MUL_1750|M.ulcerans_Agy99 PGFG-----GPAKPP-----FSVGEAISWAWNRFTQNAMALVVPIVIYGL
MLBr_02395|M.leprae_Br4923 PAIRSLPKEAYTFWVTRVLAYVIDNIPATVLLGIGMLIQTLT--------
:
Mb1265c|M.bovis_AF2122/97 --------------------------------------------------
Rv1233c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4208|M.marinum_M --------------------------------------------------
MAV_1372|M.avium_104 --------------------------------------------------
Mflv_2210|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4486|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3105|M.thermoresistible__bu --------------------------------------------------
MAB_1370c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5268|M.smegmatis_MC2_155 VYAILQGIVNGISGAF---TSTSSADGF-------ELSMATGGGVVSIIG
MUL_1750|M.ulcerans_Agy99 ILSAVGGVMVGLFFAFSDRTSTTYTDAYGNTSETVNMTMSPLASIVMFIG
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
Mb1265c|M.bovis_AF2122/97 -------------------GGYYPEPGYLDGYGPSQPGMNTMALVSLISA
Rv1233c|M.tuberculosis_H37Rv -------------------GGYYPEPGYLDGYGPSQPGMNTMALVSLISA
MMAR_4208|M.marinum_M ------------------PGGYYPPPDPMAGYGPALPGMNTMAIVALVSS
MAV_1372|M.avium_104 ------------------YGGYPPQPPLLGG----QPGTNGLAIASLIAS
Mflv_2210|M.gilvum_PYR-GCK --------------------GGYPGADYGYG-TPAQQGSNGMAIGSLVTS
Mvan_4486|M.vanbaalenii_PYR-1 -------------------AGGYPDAGYGYG-APAPQGTNSLAIASLVAS
TH_3105|M.thermoresistible__bu --------------------GYYGYPQGYSQGYTQPPSTNTLSIWSLVIS
MAB_1370c|M.abscessus_ATCC_199 --------------------PGYADP-YGYGAYGQTGGTNGLAIASLITS
MSMEG_5268|M.smegmatis_MC2_155 AIITLIVTAVIQAAYISGVLEIANGQPVTIGSFFKPRNVGDVIIATVIVG
MUL_1750|M.ulcerans_Agy99 YLAVFAVVLFMHAGITTGCLDIADGKPVTIGSFFKPRNLGMVILTGLLVI
MLBr_02395|M.leprae_Br4923 ----------------KQEACVTDITQYNVNQYCATQPTGIGMLAFWFAW
. : .
Mb1265c|M.bovis_AF2122/97 LVGV---LCCIG------------------------------SIVGIVFG
Rv1233c|M.tuberculosis_H37Rv LVGV---LCCIG------------------------------SIVGIVFG
MMAR_4208|M.marinum_M LVGV---FCCIG------------------------------SVVAIVVG
MAV_1372|M.avium_104 FTGL---LCGIG------------------------------SVVAIVLG
Mflv_2210|M.gilvum_PYR-GCK LLALPLNIACFSGT--------------------------IASIVAVVLG
Mvan_4486|M.vanbaalenii_PYR-1 CVGL---FCCIG------------------------------SIAGIAMG
TH_3105|M.thermoresistible__bu LISIP--LLCSGLLS---------------------FLAPPAAIAGIVLG
MAB_1370c|M.abscessus_ATCC_199 IAAIVT--CYLG---------------------------IILGIVGVILG
MSMEG_5268|M.smegmatis_MC2_155 VINFVVAAILLFPGFFVPGYLFVGVPVLLIASAIIAVLFLFTTVAVLDRN
MUL_1750|M.ulcerans_Agy99 VLTAIGSVLCIVPG------------------LIFGFLAQFAIIAAVDRS
MLBr_02395|M.leprae_Br4923 LMATAYLVWNYGYRQG-------------------------ATGSSIGKT
:
Mb1265c|M.bovis_AF2122/97 AIAINQIKQTREEGYG--------------LAVAGIVIGIATLLVYMIAG
Rv1233c|M.tuberculosis_H37Rv AIAINQIKQTREEGYG--------------LAVAGIVIGIATLLVYMIAG
MMAR_4208|M.marinum_M TIAINQIKQTREDGYG--------------LAVAGIVIAVATLLIYLVVG
MAV_1372|M.avium_104 AIALDQIKRTRQDGFG--------------LAVAGIVIGIATLVVTLVVV
Mflv_2210|M.gilvum_PYR-GCK VVALNQIKTSGQSGKE--------------MAIAGIAIGVLGLIGAFVLM
Mvan_4486|M.vanbaalenii_PYR-1 VIALSQIKQTRAEGQG--------------LAVAGIIVGVITLLISGIAT
TH_3105|M.thermoresistible__bu SLGLNQIKNTGENGRA--------------LAIGGIVAGAAVLVMVVVII
MAB_1370c|M.abscessus_ATCC_199 VVALNQLKTRQQDGKG--------------IAIAGIILGAVIPVLWILVL
MSMEG_5268|M.smegmatis_MC2_155 LSGVDAVKTSFELSKANFGTVFITAVVIFLLLLAGAIACGIGLLVAYPLV
MUL_1750|M.ulcerans_Agy99 LSPIDSIKSSCATVRAELGNTALSWLVQYAVVLAGELLCFVGMLVGVPVA
MLBr_02395|M.leprae_Br4923 VMKFKVISEATGQPIG------------FGMSVVRQLAHFVDAVICCIGF
.. :. : : :
Mb1265c|M.bovis_AF2122/97 IFAIP--------------------------------------
Rv1233c|M.tuberculosis_H37Rv IFAIP--------------------------------------
MMAR_4208|M.marinum_M IFSIPSH------------------------------------
MAV_1372|M.avium_104 LFALHTH------------------------------------
Mflv_2210|M.gilvum_PYR-GCK AVVFAGSG-----------------------------------
Mvan_4486|M.vanbaalenii_PYR-1 VAVMAS-------------------------------------
TH_3105|M.thermoresistible__bu LMIMLAAAAGA--------------------------------
MAB_1370c|M.abscessus_ATCC_199 IVIAAGSSSTSGSF-----------------------------
MSMEG_5268|M.smegmatis_MC2_155 ALIEVYAFRRLTGAPIAPPTQ----------------------
MUL_1750|M.ulcerans_Agy99 SLIQTYTWRKLSGGQVVELSQPGPPAGLPPGPPPGAPPGPQFG
MLBr_02395|M.leprae_Br4923 LFPLWDSKRQTLADKIMTTVCLPI-------------------