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MTSSDNDAGRGESSDSTASGSEPSSAGYEPPPIEQTQSAPPPAQDYLPPPAYDAPPAYPPSPGYEQQPGY PPSGGFAAPDYPPPPAGYPPPYPDAGPPPPHPGYGAPGYGAPSYPPPPPYGTMPGGYPPAGGYPDAGYGY GAPAPQGTNSLAIASLVASCVGLFCCIGSIAGIAMGVIALSQIKQTRAEGQGLAVAGIIVGVITLLISGI ATVAVMAS
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_4486 | - | - | 100% (218) | hypothetical protein Mvan_4486 |
M. vanbaalenii PYR-1 | Mvan_0029 | - | 7e-20 | 44.06% (143) | FHA domain-containing protein |
M. vanbaalenii PYR-1 | Mvan_4673 | - | 2e-18 | 33.00% (200) | hypothetical protein Mvan_4673 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1265c | - | 1e-44 | 50.71% (211) | hypothetical protein Mb1265c |
M. gilvum PYR-GCK | Mflv_2210 | - | 4e-51 | 46.72% (244) | hypothetical protein Mflv_2210 |
M. tuberculosis H37Rv | Rv1233c | - | 4e-44 | 49.28% (209) | hypothetical protein Rv1233c |
M. leprae Br4923 | MLBr_02395 | Ag36 | 6e-12 | 43.27% (104) | proline rich antigenic protein |
M. abscessus ATCC 19977 | MAB_1370c | - | 3e-29 | 40.93% (215) | hypothetical protein MAB_1370c |
M. marinum M | MMAR_4208 | - | 8e-43 | 48.85% (217) | proline and glycine rich transmembrane protein |
M. avium 104 | MAV_1372 | - | 4e-39 | 46.57% (204) | hypothetical protein MAV_1372 |
M. smegmatis MC2 155 | MSMEG_5063 | - | 4e-25 | 38.15% (173) | integral membrane protein |
M. thermoresistible (build 8) | TH_3105 | - | 1e-25 | 34.68% (248) | PUTATIVE - |
M. ulcerans Agy99 | MUL_4272 | - | 6e-20 | 36.95% (203) | hypothetical protein MUL_4272 |
CLUSTAL 2.0.9 multiple sequence alignment Mvan_4486|M.vanbaalenii_PYR-1 ---MTSSDNDAGRGESSDSTASG-------SEPSSAGYEPPPIEQTQSAP Mflv_2210|M.gilvum_PYR-GCK ---MTSSDNDADRVESSESAADG-------SEPTPAGYEAPSIEHTPSAP Mb1265c|M.bovis_AF2122/97 ---MTAPSGSSG--ESAHDAAGG-------PPPVGERPPEQPIA---DAP Rv1233c|M.tuberculosis_H37Rv ---MTAPSGSSG--ESAHDAAGG-------PPPVGERPPEQPIA---DAP MMAR_4208|M.marinum_M ---MTAPGGSFD--EGAHDGAAS-------PPP-GEQPSEQPFSPPPDAP MAV_1372|M.avium_104 MNTMTAPGAGFG--ESAQHDHHG-------DQAHGDKPNDDATS----AP MSMEG_5063|M.smegmatis_MC2_155 ---MTNP---DG--PAGGTP-------------PSGSGEPPAYQ------ TH_3105|M.thermoresistible__bu ---MTNPGNADGTPPAEGQPGPSETGADDLAREPTGGADPTASEHTPDQP MAB_1370c|M.abscessus_ATCC_199 ---MTTPGHEPS--GSSPDASSG------YEYPSLEKSAPPADPAVAANP MUL_4272|M.ulcerans_Agy99 MSTLPPPGYPVEPNSGAPGYEAAGYPPSGYADPPPAYGPPPAYGPPPGYG MLBr_02395|M.leprae_Br4923 ---MTDQPPPSGSNPTPAPPPPG----------SSGGYEPSFAPSELGSA :. Mvan_4486|M.vanbaalenii_PYR-1 PPAQDYLPPPAYDA---------------PPAYPPSPG------YEQQP- Mflv_2210|M.gilvum_PYR-GCK DTSSDDTPPHGYTP---------------PPAYNPPPSSTPPM-YGTPPN Mb1265c|M.bovis_AF2122/97 WAPP-ASSPMADHP---------------PPAY-PPSG------YPP--- Rv1233c|M.tuberculosis_H37Rv WAPP-ASSPMANHP---------------PPAY-PPSG------YPP--- MMAR_4208|M.marinum_M WAAPEAASPADDYP---------------APSY-PPPA------YPPEPV MAV_1372|M.avium_104 HAQPAPWEPPAGSV---------------PPPY-PPPG------YPA--- MSMEG_5063|M.smegmatis_MC2_155 ------------------------------PGYPPAQPDP----FAP--- TH_3105|M.thermoresistible__bu TAADQAADQAGDRPDEQAFDGSWAAAGETAPAYGESPPAG----FAP--- MAB_1370c|M.abscessus_ATCC_199 TPSPPPAWEAPGQP---------------TASYPAYPAS----------- MUL_4272|M.ulcerans_Agy99 APPPGYGPPPGYAP--------------PPPGYGPPPGYGPPPGYGPPPP MLBr_02395|M.leprae_Br4923 YPPPTAPPVGGSYP------------------PPPPPGG----------- Mvan_4486|M.vanbaalenii_PYR-1 ---GYPPSGG----FAAPDYPPPPAGYPPP-YPDAGPPPP---HPGYGA- Mflv_2210|M.gilvum_PYR-GCK --TGYPAPGD----FTSPPYPPPPAGYGAQNYPPPGYGAQGYGAQGYGP- Mb1265c|M.bovis_AF2122/97 ---AYQPG-------YPTDYPPPMP---PGGYAPPGYPPPGTSSAGYGD- Rv1233c|M.tuberculosis_H37Rv ---AYQPG-------YPTGYPPPMP---PGGYAPPGYPPPGTSSAGYGD- MMAR_4208|M.marinum_M GPGGYPPD-------YATGYPP--P---PG-YPPPGYPPYGAAAGEYGG- MAV_1372|M.avium_104 ---DYPPG-------YPPPYPPPAPS--PVPPPPPGYGPP--PPPGYGP- MSMEG_5063|M.smegmatis_MC2_155 --VDYP-------------YSPPP-----AAFPPP--YPP--PQPGFSY- TH_3105|M.thermoresistible__bu --LDYPGAGAGTEPYQPSGYPAPPPG---AQYPPP--YPPGPQQPGYGYP MAB_1370c|M.abscessus_ATCC_199 ---AYPTAPP-----AYPTAPPPYPTASQAAYPQYGQSYPSYQPGQPGT- MUL_4272|M.ulcerans_Agy99 ---GYGPPLVPG--AVKPGIIPLRPLTLSDIFNGAVGYIRANPKATLGLT MLBr_02395|M.leprae_Br4923 ---SYPPPPP-----PGGSYPPPPPSTGAYAPPPPGPAIRSLPKEAYTFW * . Mvan_4486|M.vanbaalenii_PYR-1 ------------PGYGAPSYPPPPPYGTMPGGYPP--------AGGYPDA Mflv_2210|M.gilvum_PYR-GCK ------------QGYGAQSYGAQG-YPSPYGAYP----------GGYPGA Mb1265c|M.bovis_AF2122/97 ------------IPY-PPMPPP-------YGGSP---------GGYYPEP Rv1233c|M.tuberculosis_H37Rv ------------IPY-PPMPPP-------YGGSP---------GGYYPEP MMAR_4208|M.marinum_M ------------TPY-PPPPPPPAPMAAPYGAPPPNYPPPSYPGGYYPPP MAV_1372|M.avium_104 ------------PGY-PGGYYP---------GPD--------YGGYPPQP MSMEG_5063|M.smegmatis_MC2_155 ------------APFDP--------------------------------- TH_3105|M.thermoresistible__bu APPPYDAPRYPTPPYDPAQPPQFGAGQFGAAGYPDPNQPG--YPGYYGYP MAB_1370c|M.abscessus_ATCC_199 --------------YPPPGYPVAG----GYPGYPP----------PGYAD MUL_4272|M.ulcerans_Agy99 ----------AIVVVVMQVITLLAAIGPLEAASRFDTHPSELSWGVVGAW MLBr_02395|M.leprae_Br4923 VTR--------VLAYVIDNIPATVLLGIGMLIQTLTKQEACVTDITQYNV Mvan_4486|M.vanbaalenii_PYR-1 GYGYG-APAPQGTNSLAIASLVASCVGL-------FCCIG----SIAGIA Mflv_2210|M.gilvum_PYR-GCK DYGYG-TPAQQGSNGMAIGSLVTSLLALPL----NIACFSGTIASIVAVV Mb1265c|M.bovis_AF2122/97 GYLDGYGPSQPGMNTMALVSLISALVGV-------LCCIG----SIVGIV Rv1233c|M.tuberculosis_H37Rv GYLDGYGPSQPGMNTMALVSLISALVGV-------LCCIG----SIVGIV MMAR_4208|M.marinum_M DPMAGYGPALPGMNTMAIVALVSSLVGV-------FCCIG----SVVAIV MAV_1372|M.avium_104 PLLGG----QPGTNGLAIASLIASFTGL-------LCGIG----SVVAIV MSMEG_5063|M.smegmatis_MC2_155 ------YGRPPGTNGLAIASLVCSLA-------GMLCCLP----GLAGLV TH_3105|M.thermoresistible__bu QGYSQGYTQPPSTNTLSIWSLVISLISIPLLCSGLLSFLAPP-AAIAGIV MAB_1370c|M.abscessus_ATCC_199 PYGYGAYGQTGGTNGLAIASLITSIAAIVT------CYLG-IILGIVGVI MUL_4272|M.ulcerans_Agy99 TGSAAAGLLVSWLGGMLLSGILTVVVGRAVFG--SPITISEAWARVRGRI MLBr_02395|M.leprae_Br4923 NQYCATQPTGIGMLAFWFAWLMATAYLVWN-----YGYRQGATGSSIGKT : : :: . Mvan_4486|M.vanbaalenii_PYR-1 MGVIALSQIKQTRAEGQGLAVAGIIVGVITLLISGIATVAVMAS------ Mflv_2210|M.gilvum_PYR-GCK LGVVALNQIKTSGQSGKEMAIAGIAIGVLGLIGAFVLMAVVFAGSG---- Mb1265c|M.bovis_AF2122/97 FGAIAINQIKQTREEGYGLAVAGIVIGIATLLVYMIAGIFAIP------- Rv1233c|M.tuberculosis_H37Rv FGAIAINQIKQTREEGYGLAVAGIVIGIATLLVYMIAGIFAIP------- MMAR_4208|M.marinum_M VGTIAINQIKQTREDGYGLAVAGIVIAVATLLIYLVVGIFSIPSH----- MAV_1372|M.avium_104 LGAIALDQIKRTRQDGFGLAVAGIVIGIATLVVTLVVVLFALHTH----- MSMEG_5063|M.smegmatis_MC2_155 LGILGMRETRRTGQDGYGIAVAGTVIGAFVTVGIALYFVLLLIGAAVAPN TH_3105|M.thermoresistible__bu LGSLGLNQIKNTGENGRALAIGGIVAGAAVLVMVVVIILMIMLAAAAGA- MAB_1370c|M.abscessus_ATCC_199 LGVVALNQLKTRQQDGKGIAIAGIILGAVIPVLWILVLIVIAAGSSSTSG MUL_4272|M.ulcerans_Agy99 LALIGLALLEGAGLVALAGLVVVILVGVAAAANGATAALLGFPLVLLVGL MLBr_02395|M.leprae_Br4923 VMKFKVISEATGQPIGFGMSVVRQLAHFVDAVICCIGFLFPLWDSKRQTL . . : . : Mvan_4486|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2210|M.gilvum_PYR-GCK -------------------------------------------------- Mb1265c|M.bovis_AF2122/97 -------------------------------------------------- Rv1233c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4208|M.marinum_M -------------------------------------------------- MAV_1372|M.avium_104 -------------------------------------------------- MSMEG_5063|M.smegmatis_MC2_155 -------------------------------------------------- TH_3105|M.thermoresistible__bu -------------------------------------------------- MAB_1370c|M.abscessus_ATCC_199 SF------------------------------------------------ MUL_4272|M.ulcerans_Agy99 LVAYLYTVLMFAPVLIVLERLPLVDAITRSFALVTGGFWRVLGIRLLTAI MLBr_02395|M.leprae_Br4923 ADKIMTTVCLPI-------------------------------------- Mvan_4486|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2210|M.gilvum_PYR-GCK -------------------------------------------------- Mb1265c|M.bovis_AF2122/97 -------------------------------------------------- Rv1233c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4208|M.marinum_M -------------------------------------------------- MAV_1372|M.avium_104 -------------------------------------------------- MSMEG_5063|M.smegmatis_MC2_155 -------------------------------------------------- TH_3105|M.thermoresistible__bu -------------------------------------------------- MAB_1370c|M.abscessus_ATCC_199 -------------------------------------------------- MUL_4272|M.ulcerans_Agy99 VVGLVGGAISAPFGIVGQILLGATASEGSTGMFLVGMTLSSIGSAISQII MLBr_02395|M.leprae_Br4923 -------------------------------------------------- Mvan_4486|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2210|M.gilvum_PYR-GCK -------------------------------------------------- Mb1265c|M.bovis_AF2122/97 -------------------------------------------------- Rv1233c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4208|M.marinum_M -------------------------------------------------- MAV_1372|M.avium_104 -------------------------------------------------- MSMEG_5063|M.smegmatis_MC2_155 -------------------------------------------------- TH_3105|M.thermoresistible__bu -------------------------------------------------- MAB_1370c|M.abscessus_ATCC_199 -------------------------------------------------- MUL_4272|M.ulcerans_Agy99 TAPFTAGVVVLLYTDRRMRAEAFDLVLQTGAAGGPAAVESTDTLWLTRPL MLBr_02395|M.leprae_Br4923 --------------------------------------------------