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NTMTAPGAGFGESAQHDHHGDQAHGDKPNDDATSAPHAQPAPWEPPAGSVPPPYPPPGYPADYPPGYPPP YPPPAPSPVPPPPPGYGPPPPPGYGPPGYPGGYYPGPDYGGYPPQPPLLGGQPGTNGLAIASLIASFTGL LCGIGSVVAIVLGAIALDQIKRTRQDGFGLAVAGIVIGIATLVVTLVVVLFALHTH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1372 | - | - | 100% (197) | hypothetical protein MAV_1372 |
| M. avium 104 | MAV_3436 | - | 1e-18 | 53.57% (84) | hypothetical protein MAV_3436 |
| M. avium 104 | MAV_1219 | - | 7e-13 | 36.18% (152) | hypothetical protein MAV_1219 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1265c | - | 1e-47 | 50.00% (210) | hypothetical protein Mb1265c |
| M. gilvum PYR-GCK | Mflv_2210 | - | 5e-26 | 39.45% (218) | hypothetical protein Mflv_2210 |
| M. tuberculosis H37Rv | Rv1233c | - | 2e-47 | 50.00% (210) | hypothetical protein Rv1233c |
| M. leprae Br4923 | MLBr_02395 | Ag36 | 3e-14 | 48.19% (83) | proline rich antigenic protein |
| M. abscessus ATCC 19977 | MAB_3781 | - | 5e-28 | 46.63% (163) | hypothetical protein MAB_3781 |
| M. marinum M | MMAR_4208 | - | 1e-48 | 46.98% (232) | proline and glycine rich transmembrane protein |
| M. smegmatis MC2 155 | MSMEG_5063 | - | 2e-25 | 42.11% (152) | integral membrane protein |
| M. thermoresistible (build 8) | TH_3105 | - | 2e-26 | 38.39% (224) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_1750 | - | 1e-18 | 34.11% (214) | proline and glycine rich transmembrane protein |
| M. vanbaalenii PYR-1 | Mvan_4486 | - | 4e-39 | 46.57% (204) | hypothetical protein Mvan_4486 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1265c|M.bovis_AF2122/97 ---MTAPSGSSG--ESAHDA--------------AGGPPPVGERPPEQ--
Rv1233c|M.tuberculosis_H37Rv ---MTAPSGSSG--ESAHDA--------------AGGPPPVGERPPEQ--
MMAR_4208|M.marinum_M ---MTAPGGSFD--EGAHDG--------------AASPPP-GEQPSEQ--
MAV_1372|M.avium_104 MNTMTAPGAGFG--ESAQHD--------------HHGDQAHGDKPNDD--
Mflv_2210|M.gilvum_PYR-GCK ---MTSSDNDADRVESSESA--------------ADGSEPTPAGYEAP--
Mvan_4486|M.vanbaalenii_PYR-1 ---MTSSDNDAGRGESSDST--------------ASGSEPSSAGYEPP--
MSMEG_5063|M.smegmatis_MC2_155 ---MTNP---DG--PAGGTP-------------PSGSGEPPAYQ------
TH_3105|M.thermoresistible__bu ---MTNPGNADGTPPAEGQPGPSETGADDLAREPTGGADPTASEHTPDQP
MAB_3781|M.abscessus_ATCC_1997 ---MTQPPAGPPPPDPGQPE-------------FPPYPTPTSSGYPPVEP
MUL_1750|M.ulcerans_Agy99 ---MSQPPENPGNQADPQDGDQS----------TPGYPPPPNYGTPPPPP
MLBr_02395|M.leprae_Br4923 ---MTDQPPPSGSNPTPAPP-----------------PPGSSGGYEPS--
*:
Mb1265c|M.bovis_AF2122/97 -------------PIA---DAPWAPP-ASSPMADHPPPAY-PPSG-----
Rv1233c|M.tuberculosis_H37Rv -------------PIA---DAPWAPP-ASSPMANHPPPAY-PPSG-----
MMAR_4208|M.marinum_M -------------PFSPPPDAPWAAPEAASPADDYPAPSY-PPPA-----
MAV_1372|M.avium_104 -------------ATS----APHAQPAPWEPPAGSVPPPY-PPPG-----
Mflv_2210|M.gilvum_PYR-GCK -------------SIEHTPSAPDTSSDDTPPHGYTPPPAYNPPPSSTPPM
Mvan_4486|M.vanbaalenii_PYR-1 -------------PIEQTQSAPPPAQDYLPPPAYDAPPAYPPSPG-----
MSMEG_5063|M.smegmatis_MC2_155 ------------------------------PGYPPAQPDPFAPVDYP---
TH_3105|M.thermoresistible__bu TAADQAADQAGDRPDEQAFDGSWAAAGETAPAYGESPPAGFAPLDYPGAG
MAB_3781|M.abscessus_ATCC_1997 SPG----------AYPPIPPAAGPGAEPYPPYPQANPAGYPPPPG-----
MUL_1750|M.ulcerans_Agy99 PPG----------YGAPPAGPPGYGAPPPPPGYGTPPPPPPPGYGQAPGG
MLBr_02395|M.leprae_Br4923 --------------FAPSELGSAYPPPTAPPVGGSYPPPPPPGGS-----
* . .
Mb1265c|M.bovis_AF2122/97 YPP------AYQPG-----YPTDYPPPMPPGGYAPPGYPPPGT-SSAGYG
Rv1233c|M.tuberculosis_H37Rv YPP------AYQPG-----YPTGYPPPMPPGGYAPPGYPPPGT-SSAGYG
MMAR_4208|M.marinum_M YPPEPVGPGGYPPD-----YATGYPP--PPG-YPPPGYPPYGA-AAGEYG
MAV_1372|M.avium_104 YPA------DYPPG-----YPPPYPPP-APSPVPPP--PP-------GYG
Mflv_2210|M.gilvum_PYR-GCK YGTPPNT--GYPAPG--DFTSPPYPP--PPAGYGAQNYPPPGY-GAQGYG
Mvan_4486|M.vanbaalenii_PYR-1 YEQQP----GYPPSG--GFAAPDYPP--PPAGYPPP-YPDAGP-PPP---
MSMEG_5063|M.smegmatis_MC2_155 ----------YSPPP--AAFPPPYPP--PQPGFSY---------------
TH_3105|M.thermoresistible__bu AGTEPYQPSGYPAPPPGAQYPPPYPPGPQQPGYGYP--APPPY-DAPRYP
MAB_3781|M.abscessus_ATCC_1997 YPPPASPYGAYPAAG---AYPPVESARGTNGFAIASLILGIVP-ICAGIF
MUL_1750|M.ulcerans_Agy99 YAPPGYNPPPPPPPG----YGPPPAGYSTQPGFGGPAKPPFSVGEAISWA
MLBr_02395|M.leprae_Br4923 YPPPPPPGGSYPPPP---PSTGAYAPPPPGPAIRSLPKEAYTFWVTRVLA
. .
Mb1265c|M.bovis_AF2122/97 DIPYPPMPPP-------YGGSP---------GGYYP----EPGYLDGYGP
Rv1233c|M.tuberculosis_H37Rv DIPYPPMPPP-------YGGSP---------GGYYP----EPGYLDGYGP
MMAR_4208|M.marinum_M GTPYPPPPPPPAPMAAPYGAPPPNYPPPSYPGGYYP----PPDPMAGYGP
MAV_1372|M.avium_104 ----PPPPPG-------YGPPG-------YPGGYYP----GPD-YGGYPP
Mflv_2210|M.gilvum_PYR-GCK AQGYGPQGYG----AQSYGAQG-----YPSPYGAYP--GGYPGADYGYGT
Mvan_4486|M.vanbaalenii_PYR-1 HPGYGAPGYG----APSYPPPPP----YGTMPGGYPPAGGYPDAGYGYGA
MSMEG_5063|M.smegmatis_MC2_155 -APFDP-----------------------------------------YGR
TH_3105|M.thermoresistible__bu TPPYDPAQPPQFG-AGQFGAAGYPDPNQPGYPGYYG---YPQGYSQGYTQ
MAB_3781|M.abscessus_ATCC_1997 GVVFGFISLN---QIKRTGQNGRGMAIAGIVLGFIWMIVLAVVVAVGAGN
MUL_1750|M.ulcerans_Agy99 WNRFTQNAMALVVPIVIYGLILSAVGGVMVGLFFAFSDRTSTTYTDAYGN
MLBr_02395|M.leprae_Br4923 YVIDNIPATVLLGIGMLIQTLTKQEACVTDITQYNVN-----QYCATQPT
Mb1265c|M.bovis_AF2122/97 -------------SQPGMNTMALVSLISALVGV-----------------
Rv1233c|M.tuberculosis_H37Rv -------------SQPGMNTMALVSLISALVGV-----------------
MMAR_4208|M.marinum_M -------------ALPGMNTMAIVALVSSLVGV-----------------
MAV_1372|M.avium_104 QPP-------LLGGQPGTNGLAIASLIASFTGL-----------------
Mflv_2210|M.gilvum_PYR-GCK P------------AQQGSNGMAIGSLVTSLLALPL---------------
Mvan_4486|M.vanbaalenii_PYR-1 P------------APQGTNSLAIASLVASCVGL-----------------
MSMEG_5063|M.smegmatis_MC2_155 P--------------PGTNGLAIASLVCSLA-------------------
TH_3105|M.thermoresistible__bu P--------------PSTNTLSIWSLVISLISIPLLC-------------
MAB_3781|M.abscessus_ATCC_1997 SAKRDESGHVTQSGDMDVTKLRVGDCVADLGEKSYYT-------------
MUL_1750|M.ulcerans_Agy99 TSETVN----MTMSPLASIVMFIGYLAVFAVVLFMHAGITTGCLDIADGK
MLBr_02395|M.leprae_Br4923 G--------------IGMLAFWFAWLMATAYLVWNYG-------------
: .
Mb1265c|M.bovis_AF2122/97 -------------------------LCCIG----SIVGIVFGAIAINQIK
Rv1233c|M.tuberculosis_H37Rv -------------------------LCCIG----SIVGIVFGAIAINQIK
MMAR_4208|M.marinum_M -------------------------FCCIG----SVVAIVVGTIAINQIK
MAV_1372|M.avium_104 -------------------------LCGIG----SVVAIVLGAIALDQIK
Mflv_2210|M.gilvum_PYR-GCK ------------------------NIACFSGTIASIVAVVLGVVALNQIK
Mvan_4486|M.vanbaalenii_PYR-1 -------------------------FCCIG----SIAGIAMGVIALSQIK
MSMEG_5063|M.smegmatis_MC2_155 -----------------------GMLCCLP----GLAGLVLGILGMRETR
TH_3105|M.thermoresistible__bu --------------------S--GLLSFLAPP-AAIAGIVLGSLGLNQIK
MAB_3781|M.abscessus_ATCC_1997 --------------------TTKAIPCAQPHKAEVYAVLPLSGSSLPSQS
MUL_1750|M.ulcerans_Agy99 PVTIGSFFKPRNLGMVILTGLLVIVLTAIGSVLCIVPGLIFGFLAQFAII
MLBr_02395|M.leprae_Br4923 --------------------------YRQGATGSSIGKTVMKFKVISEAT
.
Mb1265c|M.bovis_AF2122/97 QTRE-----------------------------------EGYGLAVAGIV
Rv1233c|M.tuberculosis_H37Rv QTRE-----------------------------------EGYGLAVAGIV
MMAR_4208|M.marinum_M QTRE-----------------------------------DGYGLAVAGIV
MAV_1372|M.avium_104 RTRQ-----------------------------------DGFGLAVAGIV
Mflv_2210|M.gilvum_PYR-GCK TSGQ-----------------------------------SGKEMAIAGIA
Mvan_4486|M.vanbaalenii_PYR-1 QTRA-----------------------------------EGQGLAVAGII
MSMEG_5063|M.smegmatis_MC2_155 RTGQ-----------------------------------DGYGIAVAGTV
TH_3105|M.thermoresistible__bu NTGE-----------------------------------NGRALAIGGIV
MAB_3781|M.abscessus_ATCC_1997 VLDE-----------------------------------KGNEECGAELE
MUL_1750|M.ulcerans_Agy99 AAVDRSLSPIDSIKSSCATVRAELGNTALSWLVQYAVVLAGELLCFVGML
MLBr_02395|M.leprae_Br4923 GQPI------------------------------------GFGMSVVRQL
* .
Mb1265c|M.bovis_AF2122/97 IGIATLLVYMIAGIFAIP-------------------------------
Rv1233c|M.tuberculosis_H37Rv IGIATLLVYMIAGIFAIP-------------------------------
MMAR_4208|M.marinum_M IAVATLLIYLVVGIFSIPSH-----------------------------
MAV_1372|M.avium_104 IGIATLVVTLVVVLFALHTH-----------------------------
Mflv_2210|M.gilvum_PYR-GCK IGVLGLIGAFVLMAVVFAGSG----------------------------
Mvan_4486|M.vanbaalenii_PYR-1 VGVITLLISGIATVAVMAS------------------------------
MSMEG_5063|M.smegmatis_MC2_155 IGAFVTVGIALYFVLLLIGAAVAPN------------------------
TH_3105|M.thermoresistible__bu AGAAVLVMVVVIILMIMLAAAAGA-------------------------
MAB_3781|M.abscessus_ATCC_1997 SYAPSAFDDDSVQITYLYPTKRSWAQGDRAIACVATFDTQRTASIKGK-
MUL_1750|M.ulcerans_Agy99 VGVPVASLIQTYTWRKLSGGQVVELSQPGPPAGLPPGPPPGAPPGPQFG
MLBr_02395|M.leprae_Br4923 AHFVDAVICCIGFLFPLWDSKRQTLADKIMTTVCLPI------------
: