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TSSDNDADRVESSESAADGSEPTPAGYEAPSIEHTPSAPDTSSDDTPPHGYTPPPAYNPPPSSTPPMYGT PPNTGYPAPGDFTSPPYPPPPAGYGAQNYPPPGYGAQGYGAQGYGPQGYGAQSYGAQGYPSPYGAYPGGY PGADYGYGTPAQQGSNGMAIGSLVTSLLALPLNIACFSGTIASIVAVVLGVVALNQIKTSGQSGKEMAIA GIAIGVLGLIGAFVLMAVVFAGSG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2210 | - | - | 100% (235) | hypothetical protein Mflv_2210 |
| M. gilvum PYR-GCK | Mflv_0806 | - | 2e-17 | 32.52% (206) | FHA domain-containing protein |
| M. gilvum PYR-GCK | Mflv_2044 | - | 2e-16 | 32.70% (211) | integral membrane protein-like protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1265c | - | 6e-31 | 40.71% (226) | hypothetical protein Mb1265c |
| M. tuberculosis H37Rv | Rv1233c | - | 5e-31 | 40.27% (226) | hypothetical protein Rv1233c |
| M. leprae Br4923 | MLBr_00022 | - | 4e-11 | 28.43% (197) | hypothetical protein MLBr_00022 |
| M. abscessus ATCC 19977 | MAB_1370c | - | 8e-30 | 40.52% (232) | hypothetical protein MAB_1370c |
| M. marinum M | MMAR_4208 | - | 2e-26 | 39.56% (225) | proline and glycine rich transmembrane protein |
| M. avium 104 | MAV_1372 | - | 6e-26 | 39.45% (218) | hypothetical protein MAV_1372 |
| M. smegmatis MC2 155 | MSMEG_3229 | - | 2e-19 | 33.33% (204) | hypothetical protein MSMEG_3229 |
| M. thermoresistible (build 8) | TH_3105 | - | 5e-28 | 37.50% (264) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_4272 | - | 2e-16 | 48.45% (97) | hypothetical protein MUL_4272 |
| M. vanbaalenii PYR-1 | Mvan_4486 | - | 5e-51 | 46.72% (244) | hypothetical protein Mvan_4486 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2210|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4486|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1265c|M.bovis_AF2122/97 --------------------------------------------------
Rv1233c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4208|M.marinum_M --------------------------------------------------
MAV_1372|M.avium_104 --------------------------------------------------
TH_3105|M.thermoresistible__bu --------------------------------------------------
MAB_1370c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_3229|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4272|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00022|M.leprae_Br4923 MDNQKELIQRIERKLESSIDDAFARMFGGSIVPQEVEALLRREASDGVRS
Mflv_2210|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4486|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1265c|M.bovis_AF2122/97 --------------------------------------------------
Rv1233c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4208|M.marinum_M --------------------------------------------------
MAV_1372|M.avium_104 --------------------------------------------------
TH_3105|M.thermoresistible__bu --------------------------------------------------
MAB_1370c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_3229|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4272|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00022|M.leprae_Br4923 LQGNRLLAPNEYIITLGVHDLEKMKADPDLTSSAFASDLADYIHEQGWQT
Mflv_2210|M.gilvum_PYR-GCK -----------------------------MTSSDNDADRVESSESAADGS
Mvan_4486|M.vanbaalenii_PYR-1 -----------------------------MTSSDNDAGRGESSDSTASGS
Mb1265c|M.bovis_AF2122/97 ----------------------------------MTAPSGSSGESAHDAA
Rv1233c|M.tuberculosis_H37Rv ----------------------------------MTAPSGSSGESAHDAA
MMAR_4208|M.marinum_M ----------------------------------MTAPGGSFDEGAHDGA
MAV_1372|M.avium_104 -------------------------------MNTMTAPGAGFGESAQHDH
TH_3105|M.thermoresistible__bu -------MTNPGNADGTPPAEGQPGPSETGADDLAREPTGGADPTASEHT
MAB_1370c|M.abscessus_ATCC_199 ------------------------------MTTPGHEPSGSSPDASSGYE
MSMEG_3229|M.smegmatis_MC2_155 ---------------------------MFAVPAVSRWREGSLTDMTDERA
MUL_4272|M.ulcerans_Agy99 --------------------MSTLPPPGYPVEPNSGAPGYEAAGYPPSGY
MLBr_00022|M.leprae_Br4923 YGDVVVRFDQSSSLHTGQIRARSVVNPDVEPRPTVNDPVRTQSNQAFSAE
.
Mflv_2210|M.gilvum_PYR-GCK EPTPAGYEAPSIEHTP----------SAPDTSSDDTPPHGYTPPPAYNPP
Mvan_4486|M.vanbaalenii_PYR-1 EPSSAGYEPPPIEQTQ----------SAPPPAQDYLPPPAYDAPPAYPPS
Mb1265c|M.bovis_AF2122/97 GGPPPVGERPPEQPIA----------DAPWAPP-ASSPMADHPPPA-YPP
Rv1233c|M.tuberculosis_H37Rv GGPPPVGERPPEQPIA----------DAPWAPP-ASSPMANHPPPA-YPP
MMAR_4208|M.marinum_M ASPPP-GEQPSEQPFSPPP-------DAPWAAPEAASPADDYPAPS-YPP
MAV_1372|M.avium_104 HGDQAHGDKPNDDATS-----------APHAQPAPWEPPAGSVPPP-YPP
TH_3105|M.thermoresistible__bu PDQPTAADQAADQAGDRPDEQA---FDGSWAAAGETAPAYGESPPAGFAP
MAB_1370c|M.abscessus_ATCC_199 YPSLEKSAPPADPAVAANPTPS---PPPAWEAPGQPTASYPAYPASAYPT
MSMEG_3229|M.smegmatis_MC2_155 GEPGSDRPEPTESSGQPSDPGQ---TPPPTRSGESTESSDTASPPPESNP
MUL_4272|M.ulcerans_Agy99 ADPPPAYGPPPAYGPPPGYGAP---PPGYGPPPGYAPPPPGYGPPPGYGP
MLBr_00022|M.leprae_Br4923 PGVPPMTDNSSYRGGQGQGRPSDDYYGRPQDDPRGADPQGGQDPRGCYPP
. . . .
Mflv_2210|M.gilvum_PYR-GCK PSSTP----------------------------------PMYGTPPN--T
Mvan_4486|M.vanbaalenii_PYR-1 PG---------------------------------------YEQQP----
Mb1265c|M.bovis_AF2122/97 SG---------------------------------------YPP------
Rv1233c|M.tuberculosis_H37Rv SG---------------------------------------YPP------
MMAR_4208|M.marinum_M PA---------------------------------------YPPEPVGPG
MAV_1372|M.avium_104 PG---------------------------------------YPA------
TH_3105|M.thermoresistible__bu LD---------------------------------------YPGAGAGTE
MAB_1370c|M.abscessus_ATCC_199 AP-------------------------------------PAYPTAPP---
MSMEG_3229|M.smegmatis_MC2_155 PYT--------------------------------------YGASQG---
MUL_4272|M.ulcerans_Agy99 PPG--------------------------------------YGPPPPGYG
MLBr_00022|M.leprae_Br4923 KPGSYPQQAGHPPLHRPDQGGYPGQGGYEDQRAYHDQGQGGYPSPYEQRP
*
Mflv_2210|M.gilvum_PYR-GCK GYPAPGDFTSPPYPPPPAGYGAQNYPPPGY---GAQGYGAQGYGPQGYGA
Mvan_4486|M.vanbaalenii_PYR-1 GYPPSGGFAAPDYPPPPAGYPPP-YPDAGP---PPP---HPGYGAPGYGA
Mb1265c|M.bovis_AF2122/97 AYQPGYPTDYPPPMP-PGGYAP-----PGY---PPPGTSSAGYGDIPY-P
Rv1233c|M.tuberculosis_H37Rv AYQPGYPTGYPPPMP-PGGYAP-----PGY---PPPGTSSAGYGDIPY-P
MMAR_4208|M.marinum_M GYPPDYATGYPP--P-PG-YPP-----PGY---PPYGAAAGEYGGTPY-P
MAV_1372|M.avium_104 DYPPGYPPPYPPPAPSPVPPPP-----PGY---GPP--PPPGYGPPGY-P
TH_3105|M.thermoresistible__bu PYQPSGYPAPPPGAQYPPPYPPG-PQQPGYGYPAPPPYDAPRYPTPPY-D
MAB_1370c|M.abscessus_ATCC_199 PYPTASQAAYPQYGQSYPSYQPG----------QPGTYPPPGYPVAGG-Y
MSMEG_3229|M.smegmatis_MC2_155 AYDTASQAPYGTAPQAPYGSQP---------------YGSQPYGAYPGAY
MUL_4272|M.ulcerans_Agy99 PPLVPGAVKPGIIPLRPLTLSDIFNGAVGYIR-ANPKATLGLTAIVVVVM
MLBr_00022|M.leprae_Br4923 ATPGGYGSQGHDQGYRPGSYGPPSGGQPGYGGYGDYGRGPARPDEGSYTP
Mflv_2210|M.gilvum_PYR-GCK QSYGAQG-YPSPYGAYP---------GGYPG--ADYGYGTPAQQGSNGMA
Mvan_4486|M.vanbaalenii_PYR-1 PSYPPPPPYGTMPGGYPP-------AGGYPD--AGYGYGAPAPQGTNSLA
Mb1265c|M.bovis_AF2122/97 PMPPP-------YGGSP---------GGYYPEPGYLDGYGPSQPGMNTMA
Rv1233c|M.tuberculosis_H37Rv PMPPP-------YGGSP---------GGYYPEPGYLDGYGPSQPGMNTMA
MMAR_4208|M.marinum_M PPPPPPAPMAAPYGAPPPNYPPPSYPGGYYPPPDPMAGYGPALPGMNTMA
MAV_1372|M.avium_104 GGYYP---------GPD--------YGGYPPQPPLLGG----QPGTNGLA
TH_3105|M.thermoresistible__bu PAQPPQFG-AGQFGAAGYPDPNQPGYPGYYGYPQGYSQGYTQPPSTNTLS
MAB_1370c|M.abscessus_ATCC_199 PGYPP---------------------PGYADPYGYGAYG--QTGGTNGLA
MSMEG_3229|M.smegmatis_MC2_155 PGSYP---------------------PPYGGGYPAQPPAQGAAGPRNGLG
MUL_4272|M.ulcerans_Agy99 QVITLLAAIGPLEAASRFDTHPSELSWGVVGAWTGSAAAGLLVSWLGGML
MLBr_00022|M.leprae_Br4923 SGFPAPPEQRVAYPDQGGGYDQGYQHSGLGYGREDYGRQEYTQYAEN-LP
. :
Mflv_2210|M.gilvum_PYR-GCK IGSLVTSLLALP---LNIACFSGTI------ASIVAVV-----LGVVALN
Mvan_4486|M.vanbaalenii_PYR-1 IASLVASCVGL------FCCIG----------SIAGIA-----MGVIALS
Mb1265c|M.bovis_AF2122/97 LVSLISALVGV------LCCIG----------SIVGIV-----FGAIAIN
Rv1233c|M.tuberculosis_H37Rv LVSLISALVGV------LCCIG----------SIVGIV-----FGAIAIN
MMAR_4208|M.marinum_M IVALVSSLVGV------FCCIG----------SVVAIV-----VGTIAIN
MAV_1372|M.avium_104 IASLIASFTGL------LCGIG----------SVVAIV-----LGAIALD
TH_3105|M.thermoresistible__bu IWSLVISLISI------PLLCSGLLSFLAPPAAIAGIV-----LGSLGLN
MAB_1370c|M.abscessus_ATCC_199 IASLITSIAAIVTCYLG------------IILGIVGVI-----LGVVALN
MSMEG_3229|M.smegmatis_MC2_155 IAALIAAIAGLVLC---WSIIGG------LIVGVVAIV-----LGFLGHG
MUL_4272|M.ulcerans_Agy99 LSGILTVVVGR-------AVFGSPITISEAWARVRGRI-----LALIGLA
MLBr_00022|M.leprae_Br4923 GGVYAPSSGGYAEPAGRDYDYGQPGAANDYSQPVIGGYGGYGALGSAVIL
. : . ..
Mflv_2210|M.gilvum_PYR-GCK QIKTSGQSGKEMAIAGIAIGVLGLIGAFVLMAVVFAGSG-----------
Mvan_4486|M.vanbaalenii_PYR-1 QIKQTRAEGQGLAVAGIIVGVITLLISGIATVAVMAS-------------
Mb1265c|M.bovis_AF2122/97 QIKQTREEGYGLAVAGIVIGIATLLVYMIAGIFAIP--------------
Rv1233c|M.tuberculosis_H37Rv QIKQTREEGYGLAVAGIVIGIATLLVYMIAGIFAIP--------------
MMAR_4208|M.marinum_M QIKQTREDGYGLAVAGIVIAVATLLIYLVVGIFSIPSH------------
MAV_1372|M.avium_104 QIKRTRQDGFGLAVAGIVIGIATLVVTLVVVLFALHTH------------
TH_3105|M.thermoresistible__bu QIKNTGENGRALAIGGIVAGAAVLVMVVVIILMIMLAAAAGA--------
MAB_1370c|M.abscessus_ATCC_199 QLKTRQQDGKGIAIAGIILGAVIPVLWILVLIVIAAGSSSTSGSF-----
MSMEG_3229|M.smegmatis_MC2_155 RAKRGEATNGGVAIAGIVLGGIAVVLSLAFIAIWATLGFKWFEELGGREY
MUL_4272|M.ulcerans_Agy99 LLEGAGLVALAGLVVVILVGVAAAANGATAALLGFPLVLLVGLLVAYLYT
MLBr_00022|M.leprae_Br4923 QLDDGSGRTYQLREGSNIVGRGQDAQFRLPDTGVSRRHLEIRWDGQVALL
. .
Mflv_2210|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4486|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1265c|M.bovis_AF2122/97 --------------------------------------------------
Rv1233c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4208|M.marinum_M --------------------------------------------------
MAV_1372|M.avium_104 --------------------------------------------------
TH_3105|M.thermoresistible__bu --------------------------------------------------
MAB_1370c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_3229|M.smegmatis_MC2_155 IACLEDAGNDQAAQERCRVQFEERVEDEFGTPQSR---------------
MUL_4272|M.ulcerans_Agy99 VLMFAPVLIVLERLPLVDAITRSFALVTGGFWRVLGIRLLTAIVVGLVGG
MLBr_00022|M.leprae_Br4923 SDLNSTNGTTVNNAPVQEWQLADGDVIRLGHSEIIVRIH-----------
Mflv_2210|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4486|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1265c|M.bovis_AF2122/97 --------------------------------------------------
Rv1233c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4208|M.marinum_M --------------------------------------------------
MAV_1372|M.avium_104 --------------------------------------------------
TH_3105|M.thermoresistible__bu --------------------------------------------------
MAB_1370c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_3229|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4272|M.ulcerans_Agy99 AISAPFGIVGQILLGATASEGSTGMFLVGMTLSSIGSAISQIITAPFTAG
MLBr_00022|M.leprae_Br4923 --------------------------------------------------
Mflv_2210|M.gilvum_PYR-GCK -------------------------------------------
Mvan_4486|M.vanbaalenii_PYR-1 -------------------------------------------
Mb1265c|M.bovis_AF2122/97 -------------------------------------------
Rv1233c|M.tuberculosis_H37Rv -------------------------------------------
MMAR_4208|M.marinum_M -------------------------------------------
MAV_1372|M.avium_104 -------------------------------------------
TH_3105|M.thermoresistible__bu -------------------------------------------
MAB_1370c|M.abscessus_ATCC_199 -------------------------------------------
MSMEG_3229|M.smegmatis_MC2_155 -------------------------------------------
MUL_4272|M.ulcerans_Agy99 VVVLLYTDRRMRAEAFDLVLQTGAAGGPAAVESTDTLWLTRPL
MLBr_00022|M.leprae_Br4923 -------------------------------------------