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M. marinum M MMAR_3796 (-)

annotation: type I modular polyketide synthase
coordinates: 4685825 - 4691278
length: 1817

VAVVGMACRFPGGVDSPDGLWEMVSEGRDVVSELPLDRGWDLGRLYDPDPDRLGCVYTRGGGFLSGVADF
DAGFFGISPREALGMDPQQRLMLEIAWETFESAGIDPHSLRGSQTGVFAGVMSSHYEEIGGDQAEGCLAV
GTEASVVSGRVAFTFGLEGPAVSVDTACSSSLVAIHQAGQSLRGGECSMALAGGVMVMAVPSTLVEFSRK
RGLSPDGRCRSFAAAADGTGFAEGAGLVLLERLSDARRHGHQVLAVIRGSAINQDGASKRLTAPNGRAQE
RVIRSALTAAGLEVADVDVVEAHGTGTLKGDPIEAHAILATYGQDRPADRPLWLGSVKSNMGHTQAAAGV
AGVIKMIQAMRHQVMPRSLHVDSPSPRVDWASGAVELLTEQRDWTVQDGRLRRAGVSSFGISGTNAHVIL
EEAPAWSAPGHGGDSGAASPWPAVPWVVSGKSGQALAAQAGRLAGHLSADDDIDVLGVGWSLAQRSMFEH
RAVVFGAGREELLSGLADLAQGRPAGAVLTGHAHVAGKTALVFPGQGAQWLGMGQQLHAQFPIFAAAFDA
VAGELDQHLRMSLQSVLWGDNQALLNSTEFAQPALFAVEVAMLQLLRHWGIRPDFVLGHSVGEIAAAYAA
QVLSLSDAALVVAARGRLMQSLPAGGVMFAVAATEDEVTPQLVDGAGIAAINAPGSVVISGTQEAVTPIV
NDFHGRGRRVHQLAVSHAFHSPLVEPILDEFGSAISGITVGEPTISVVSNVTAALGGPEYGSPQYWVDHV
RQPVRFADSVRLLESMGATRFVEVGPGAGLSTSVEQSLASPEDVVVIPVLGKQRPEGSSALHAAAVLFTT
GATLDWSAVFDHTPAQRITLPTYAFQRRRFWLDGTSRAGDVGNVGLAAVAHALLGAVITQPDSGGVILTG
LLTPRTQPWLADHRIAGVMLFPGAGFVELAIRAGDEVNCPVLHELTLMAPLAISESGVPVQVMVGAAGES
GSRTVAVYSAEGQSDSEWILHAKGVLTVGTAEPSLMSSELSAWPPAGAEVLDIAGGYDRLAGLGYQYGPA
FQGLTAVWKRGEDVFAEIAVSEDLDVAGMEIHPALLDAALHAWVLASDAEGAASRDEGVQLPFMWQQVSL
HGVGATRLRVHLARTQSNVVDVQLCDTSGMLVFTGSLLTRPVSPEKIHAALSAAGTQDDSGLMELTWAPI
TLPEGRAGRIVAWRDQSTVDPVSEADPAGGVQADVVVWEVPATHRDVVASVHEVTHQLLAVLQSWLTVDR
AGVLVVLTRGAVGLVGERVSDLAGAAVWGMVRSAQNEHPGQVLLVDLDAAASIVDGQIVTDSDGSDMRGL
DLAALTKSGETQLVVRSQQVYAARLSAMAPTLEVADGGGVKPSSMLDPSGTVLITGGTGMAGGWLARHVV
DHYGVRHVLLASRSGDRAGGSAEIAAELAARGVQVEVVACDVADRDAVTALLARLPQQYPLTGVIHAAGV
LDDAVITSLTPDRVDTVLRAKVDAAWNLHELTRDLGVSAFVLFSSIAGTVGAPGQGNYAAANAFLDALAF
QRRADGLTATSLAWGLWERSSTMTGHLSSRDMTRMNRTGMVALTAEQAVEMFDAALVAGHPAVVAGRFDR
RMLHNPSFNAGLPPLFNELIGSPRRRTIEAGSLASQSALTQRLHGLTPEQQREMLTELVCTQIAIALGHN
NSSEINPDQAFQGLGFDSLTAVELRNRLKAATGLSLTPTLVFDYPTPRDVASYLEYQLGGSEPIDGGNDD
YVRQVQELVMSIPAKRLAQANVVDLLQKLKTDISDQLDERESASNLADMSLDDLVDVALTKFAAQQG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_3796--100% (1817)type I modular polyketide synthase
M. marinum MMMAR_0101-0.058.28% (1764) polyketide synthase PKS
M. marinum MMMAR_1762pks15/10.056.43% (1485) polyketide synthase Pks15/1

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2971cpks10.056.76% (1487) polyketide synthase PKS1
M. gilvum PYR-GCKMflv_0405-0.038.31% (1433) beta-ketoacyl synthase
M. tuberculosis H37RvRv2048cpks120.057.50% (1360) polyketide synthase pks12
M. leprae Br4923MLBr_00135-0.056.22% (1478) putative polyketide synthase
M. abscessus ATCC 19977MAB_0939-0.037.45% (1434) polyketide synthase
M. avium 104MAV_3108-0.053.96% (1501) erythronolide synthase, modules 3 and 4
M. smegmatis MC2 155MSMEG_0408-0.038.08% (1434) type I modular polyketide synthase
M. thermoresistible (build 8)TH_2454-0.031.91% (1808) PUTATIVE beta-ketoacyl synthase
M. ulcerans Agy99MUL_2005pks15/10.056.03% (1485) polyketide synthase Pks15/1
M. vanbaalenii PYR-1Mvan_1003-0.038.21% (1476) beta-ketoacyl synthase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0405|M.gilvum_PYR-GCK          ----------------------MGSAAHQGE-SAHRFAIVGYAGRFPG-A
MAB_0939|M.abscessus_ATCC_1997      ----------------------MDSAENPIE-STPRFAIIGYAARFPG-A
MSMEG_0408|M.smegmatis_MC2_155      ----------------------MVSAEHPIE-PTPSFAIIGYAARFPG-A
Mvan_1003|M.vanbaalenii_PYR-1       --------MTDLQKRALQAIEVLRARVRELEGAGDGYAIVGYALRFPG-A
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        MVDQLQHATEALRKALVQVERLKRTNRALLERSSEPIAIVGMSCRFPGGV
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          RDAESFWELLADGRDAISEVPEDR-WDVEAFFDPDPSTPGKVVTRRAGFV
MAB_0939|M.abscessus_ATCC_1997      ADAEEFWDVLREGRDAISEVPADR-WDAEEFFDPEPGAPGKVVTRRAGFV
MSMEG_0408|M.smegmatis_MC2_155      ASAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRAGFV
Mvan_1003|M.vanbaalenii_PYR-1       ADADEFWDVLRGGRDAISEVPQDR-WDADEFFDADPEAAGKMVTRRAGFV
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        DSPEGLWQMVADARDVMSEFPTDRGWDLAGLFDPDPDVRHKSYARTGGFV
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          DDVSGFDAPFFGMSTREVRLMDPQHRLLLETAWRAIEHSGTAPSELANTN
MAB_0939|M.abscessus_ATCC_1997      EDVTGFDAPFFGMSTREVRLMDPQHRLLLETAWRAVEHSGIAPTDLAETN
MSMEG_0408|M.smegmatis_MC2_155      DDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSN
Mvan_1003|M.vanbaalenii_PYR-1       EDVAGFDAPFFGVSAREAMFMDPQHRLLLETAWRAVEHSGTAPSALAGTR
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        DGVADFDPAFFGISPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGSA
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          TGVFVGLATHDYLGMASDELSYPEIEAYMAIGTSNAAAAGRISYRLGLQG
MAB_0939|M.abscessus_ATCC_1997      SGVFVGLATHDYLGMASDELTFPEIEAYMAIGTSNAAAAGRISYRLGLQG
MSMEG_0408|M.smegmatis_MC2_155      TGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQG
Mvan_1003|M.vanbaalenii_PYR-1       TGVFMGLSTHDYLGMLTDNLTHDAIEAYLGTGTSPAAAIGRISYRLGLQG
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        TGVFAGLIVGGYG------MLAEEIEGYRLTGMTSSVASGRVAYVLGLEG
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          PAVAVDTACSSSLVAIHQACQALRLGECDLALAGGANVILTPATMITFSN
MAB_0939|M.abscessus_ATCC_1997      PSVAVDTACSSSLVAIHQACQALQLGECDLALAGGANVLLTPATMITFSH
MSMEG_0408|M.smegmatis_MC2_155      PAVAVDTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSN
Mvan_1003|M.vanbaalenii_PYR-1       PAVAVDTACSSSLVAVHQACQALRLAECDVALAGGVNVLLSPATMINFSR
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        PAVSVDTACSSSLVALHMAVGSLRSGECDLALAGGVTVNATPTVFVEFSR
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          AHMLAPDGRCKTFDAAADGYVRGEGCGVIVIKRLEDAVRDGDRIRAVIRG
MAB_0939|M.abscessus_ATCC_1997      AHMLAPDGKCKTFDAAADGYVRGEGSGVIVIKRLEDAIRDGDRIRAVIRG
MSMEG_0408|M.smegmatis_MC2_155      AHMLAPDGRCKTFDAAADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRG
Mvan_1003|M.vanbaalenii_PYR-1       ARMLAPDGRCKTFDATADGYVRGEGCGVVVVKRLADAIRHGDRIRAVIRG
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        HRGLAPDGRCKPYAGRADGVGWSEGGGMLVLQRLSDARRLGHPVLAVVVG
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          SAINQDGASGGLTVPNGVAQQRVIGDALSRAGLAPGDVDYLEAHGTGTSL
MAB_0939|M.abscessus_ATCC_1997      SAINQDGASGGLTVPNGVAQQRVIADALKRAGVAPSEVGYLEAHGTGTSL
MSMEG_0408|M.smegmatis_MC2_155      SAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPADVGYLEAHGTGTSL
Mvan_1003|M.vanbaalenii_PYR-1       SAVNQDGASGGLTVPNGAAQQRVIADALTNAGLTAADVDYLEAHGTGTPL
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        SAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTL
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          GDPIEAQAAGAALGPGR-EPQRPLLIGSAKTNIGHLEAAAGIAGVIKVVL
MAB_0939|M.abscessus_ATCC_1997      GDPIEAQAAGAAYGIGR-ETNDPLLIGSAKTNIGHLEAAAGIAGVIKVIL
MSMEG_0408|M.smegmatis_MC2_155      GDPIEAQAAGEVLGAGR-APEEPLLIGSAKTNIGHLEAAAGIAGVIKVVM
Mvan_1003|M.vanbaalenii_PYR-1       GDPIEVQAAGAVLGVGR-EPDRPLLIGSVKTNIGHLEAASGIAGLLKVIL
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        GDPIEAQALLATYGQDRGEPGEPLWLGSVKSNMGHTQAAAGVAGVIKMVL
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          SLEHETLPKHLNFENPSPHIPWDRLPVEVVKESIPWRRGQRGGRPRIAGV
MAB_0939|M.abscessus_ATCC_1997      SLENELLPQHRNFQNPSPHIPWDRLPVEVVREARPWGR---NGRPRIAGV
MSMEG_0408|M.smegmatis_MC2_155      ALENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQR---NGKPRIAGV
Mvan_1003|M.vanbaalenii_PYR-1       SLEHQVLPKHLNFRSPSPHIPWNRLPVRIVDDPVPWTR---SGRSRVAGI
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        AMRHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWPAG---ARTRRAGV
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          SSFGFAGTNAHVILEEAPLAAEPAQES---VDDGRFTLLPLSARTPAALM
MAB_0939|M.abscessus_ATCC_1997      SSFGFAGTNAHVILEEAPVVSRDAVEPPAPAGGRKFSILPLSARTPAALA
MSMEG_0408|M.smegmatis_MC2_155      SSFGFAGTNAHVILEEAPAVGTPATTEP-VEDPRRYSVLPLSARTPEALV
Mvan_1003|M.vanbaalenii_PYR-1       SSFGFSGTNAHVLVEEAPRADRAGAAPQ-PAAPGGFGMLPLSARTPDALA
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        SSFGISGTNAHVIIEAVPVVPRREAGWA-----GPVVPWVVSAKSESALR
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          AVADRYRDWLVANPDATLADLCFTAGTARSHLEHRAALVVNTREAALDLL
MAB_0939|M.abscessus_ATCC_1997      QLADKYRAWLNAHPEAALADLCFTAGVGRAHLEHRAALVVNTREAAVELL
MSMEG_0408|M.smegmatis_MC2_155      RLAGEYRDWLRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELL
Mvan_1003|M.vanbaalenii_PYR-1       ATAHRLRTWLAANPDASWPDLCFTAAVGRSHLRHRAALVVDSRSSVEELL
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        GQAARLAAYVRGDDGLDVADVGWSL-AGRSVFEHRAVVVGGDRDRLLAGL
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          GALADDRPAPGLVRGESHDTPKTAWLFTGQGSQYPGMSRELFDTEPLFAE
MAB_0939|M.abscessus_ATCC_1997      SAVADDRPAPGLGRGESHDTPKTAWLFTGQGSQYPGMARELFETEPVFAD
MSMEG_0408|M.smegmatis_MC2_155      GALADDRPAPGLVRGESHEAPKTAWLFTGQGSQYPGMARELFDTEPVFAE
Mvan_1003|M.vanbaalenii_PYR-1       GALAEDRPGPGLARGECGDPPKTAWLFTGQGSQYPGMGRELFDTEPVYRE
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        DELAGDQLGGSVVRGTATAAGKTVFVFPGQGSQWLGMGIELLDTAPAFAQ
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          TLRECAAAVDGMLEKPLLDVIFDTDGVLDTDSNETLRHTSYAQPALFAVE
MAB_0939|M.abscessus_ATCC_1997      TLNRCAAAVADVLEKPLLDVIFDVD---GPEAEETLRQTSYAQPALFAVE
MSMEG_0408|M.smegmatis_MC2_155      TVRKCAEAVADILEKPLLDVIFDAD-ELDGDTESPLRHTTYAQPALFAVE
Mvan_1003|M.vanbaalenii_PYR-1       VMTRCAEAVADVLERPLLDVVFDAD------GGEALRHTSYAQPALYAVE
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        QIDACAEAFAEFVDWSLVDVLRGAP------GAPGLDRVDVVQPVLFAVM
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          MGLARLWQSWGFEPDVVLGHSVGQYAAACVAGVLSLRDGARLMAERGRLF
MAB_0939|M.abscessus_ATCC_1997      MGLARLWQSWGFEPDVVLGHSVGQYSAACVAEVFSLEDGARLIAERGRLF
MSMEG_0408|M.smegmatis_MC2_155      LGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERGRLF
Mvan_1003|M.vanbaalenii_PYR-1       MGLARLWQSWGIEPDVVLGHSVGQYAAACVAGVMGLEDGAVLLAERGRLF
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        VSLAELWKSVAVHPDAVIGHSQGEIAAAYVAGALSLRDAARVVTLRSKLL
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          GSLPSGGRMAAVFAAAERVEALTDEYPALS--VAAYNGANTVLSGPATDL
MAB_0939|M.abscessus_ATCC_1997      SSLPAGGRMAAVFTDAERAERLTDEFPSLS--VAAYNGANTVLSGPAQDL
MSMEG_0408|M.smegmatis_MC2_155      GSLPAGGRMAAVFTAPERAERLTDEYPSLS--VAAYNGANTVLSGPAKDL
Mvan_1003|M.vanbaalenii_PYR-1       GSLPEGGRMAAVFAPADRVESCTVDSPLLS--VAAYNGDNTVLSGPAGDL
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        AGLAGPGGMVSIACGADQARDLLAPFGDRVSIAVVNGPSAVVVSGEVGAL
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ERAVAGLVADGVRCDWLETSHAFHSALLDPILDDFESYARGITFTAPQRI
MAB_0939|M.abscessus_ATCC_1997      EKAIAALVADGVRCDFLETSHAFHSALLDPILDEFEAYANQFNYKTPQRI
MSMEG_0408|M.smegmatis_MC2_155      ESAVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRI
Mvan_1003|M.vanbaalenii_PYR-1       ERAVAGFSAAGVRCDWLDTSHAFHSALLDPVLEEFESCADRFEFGTPQRT
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        EELIAVCSTKELRTRRIEVDYASHSVEVEAIRGPLAEALSGIEPRSTRTV
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          LIDNRTGAALGRSVTLDAAYWRRHARQPVEFAKSVHTLADMNCKLLVEIG
MAB_0939|M.abscessus_ATCC_1997      LIDNRTGTALGRSVKLDGAYWRRHARQPVEFAKSVRTLADMNCKVLLEIG
MSMEG_0408|M.smegmatis_MC2_155      LIDNRTGSALGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIG
Mvan_1003|M.vanbaalenii_PYR-1       LVCNRSGEVLSRHARLDGQYWRRHARQPVRFAESVRTLADLGCRLLMEIG
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        FFSTVTGNRL-DTAGLDADYWYRNVRQTVLFDQAVRNACEQGYRTFIESS
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          PRPVLTAAALSAWP---DPATSPRVIASLRRTTADQRQITEAVADAYVLG
MAB_0939|M.abscessus_ATCC_1997      PQPVLTAAALRAWP---DPATAPRAIASLRRNTADHRQITEAAADAYVLG
MSMEG_0408|M.smegmatis_MC2_155      PRPVLTATALAAWP---DPATTPQVLASLRPTTADHRQITEAVAAAYAAG
Mvan_1003|M.vanbaalenii_PYR-1       PQPVLTAAAMRTWP---GTVTAPRVAASMRRKGSDRRQITEALAQAYVAG
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        PHPALITGVEETFAACTDGDSEAIVVPTLGRGDGGLHRFLLSAASAFVAG
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          HLPRFAAFRRDGARVLDLPTYPFEHRQYWFSDSRE---PVAAAPQR---G
MAB_0939|M.abscessus_ATCC_1997      HLPDFGAFQHAPARKLDLPTYPFERRQYWFSDKRDGDNRDAGNRQQNNGG
MSMEG_0408|M.smegmatis_MC2_155      HLPDFRAFRQPDARKLDLPTYPFEHRQFWFSDNRAIDRDTQTASAGSVTP
Mvan_1003|M.vanbaalenii_PYR-1       HRPETAARQHGRGRLLDLPTYPFQHRAYWFP--------QGQARTAPTDP
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        VAVNWRGTLDG-AGYVELPTYAFDKRRFWLSAEGSGADVSGLGLGASEHP
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ARTETVRLLEDG--------------------------------------
MAB_0939|M.abscessus_ATCC_1997      PRTEAVRLLEDG--------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      HRTQAVRLLEDG--------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       VHTETVRFLDEE--------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        LLGAVVDLPASGGVVLTGRLSPNVQPWLADHAVSDVVLFPGTGFVELAIR
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        AGDEVGCSVLDELTLAAPLLLPATGSVAVQVVVDAGRDSNSRGVSIFSRA
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        DAQAGWLLHAEGILRPGSVEPGADLSVWPPAGAVTVDVADGYERLATRGY
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          -----------------------RIEELAALLGGTVDDPFTFDVLNRLAA
MAB_0939|M.abscessus_ATCC_1997      -----------------------KIEELANLLGGVDGDQQTLNVLTKLAA
MSMEG_0408|M.smegmatis_MC2_155      -----------------------QIEELAALIDGETVDEQTLRVLNKLAA
Mvan_1003|M.vanbaalenii_PYR-1       -----------------------RIDELAALLDGPTGSAQTVDVLSKLAA
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        RYGPAFRGLTAMWARGEEIFAEVRLPEAAGGVGGFGVHPALLDAVLHAVV
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          QHNQQRSTESIADDRYQIRWETAAEPPVGADAADGITWLLVGDDTDATRP
MAB_0939|M.abscessus_ATCC_1997      QHNLQRTTQTIADDRYQFRWEKSPTPLSGSQAAGGVTWLLVADAAGAAQP
MSMEG_0408|M.smegmatis_MC2_155      RHNQQRSTHVDPDARYEIRWDAIASAAASTGAAA--DWILVGDDTAAVLE
Mvan_1003|M.vanbaalenii_PYR-1       RHRQQRGAQSIADARYQIRWEKSEAPGAARPTTEATTWLLVTHDSRAAQP
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        IAGDPDELALPFAWQGVSLHATGASAVRARIAPAGPSAVSVELADGLGLP
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          LVDVLAARGHRYRILGLPKSGAEEHELADTLRDAAADATDLRIVHVAALD
MAB_0939|M.abscessus_ATCC_1997      LLDVLTARGQQHRVLALPVSDADEAELVEALRSAADEDSALRIVHVAALA
MSMEG_0408|M.smegmatis_MC2_155      FADALTAGGHRHQIVALPGSDADEAQLVDTLRAASAG--ELYVVHIAAGD
Mvan_1003|M.vanbaalenii_PYR-1       IAEVLERRGHPYHIVGLPGSDADAAPAEEALRATVSQ-PRPHILYLAALE
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        VLSVASMVARPVTERQLLAAVSGSGPDRLFEVIWSPASAATSPGPTPAYQ
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          AAESDTSMKSLLRMQHRVLGGTRRLFGAAVAAQLRSPMWLVTRGAQHVTD
MAB_0939|M.abscessus_ATCC_1997      GQGS-SSAQSLLRIQHQVLGGTRRLFRAAAAAELRAPIWIVTRGAQHVIE
MSMEG_0408|M.smegmatis_MC2_155      GAAA--PMRDLLRVQHRTLGGLRRLFRAANDAELRSPIWLVTRDGQRVTD
Mvan_1003|M.vanbaalenii_PYR-1       EPGG-SAAETLGWMQHRVLAAARRLFQLAATAGARAPIWLITAGAQRITG
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        IFESVAADQDPVAGSYVRSHQALAAVQSWLTDHESGVLVVATRGAMALPR
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          TDVVAPDQTCLWGFGRAASLEHPQIWG-----------------------
MAB_0939|M.abscessus_ATCC_1997      GDTVAPEQSALWGFGRAAALELPQVWG-----------------------
MSMEG_0408|M.smegmatis_MC2_155      TDTVVPEQSCLWGFGRAAALELPHIWG-----------------------
Mvan_1003|M.vanbaalenii_PYR-1       DETVEPAQTSLWGFGRAAALEQPELWG-----------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        EDVADLAGAAVWGLVRSAQTEHPGRIVLVDSDAATDDAAIAMALATGEPQ
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ------------------------------GLADLGGGTSDEWSRLLNRI
MAB_0939|M.abscessus_ATCC_1997      ------------------------------GLADLSDAGTDEWAQFIGRV
MSMEG_0408|M.smegmatis_MC2_155      ------------------------------GLADLSGADT-EWPRLIARI
Mvan_1003|M.vanbaalenii_PYR-1       ------------------------------GLADVTTGDAEEWSALIDHI
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        VVLRGGQVYTARVRGSRAADAILVPPGDGPWRLGLGSAGTFENLRLEPVP
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          AATHDPAVMEDQVAVRGSTSYVPRLVHRDTLPSGKPLHLRADATYLVTGG
MAB_0939|M.abscessus_ATCC_1997      SVSGEASTREDQLALRGQAVHVPRLVRREELPSGKPLEVRSDATYLVTGG
MSMEG_0408|M.smegmatis_MC2_155      TSPRDG---EDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTYLVTGG
Mvan_1003|M.vanbaalenii_PYR-1       VAAPTS---EDQIAVRGREIHVARLTRCAEKANAAALELRREATYLVTGG
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        NADAPLGPGQVRVAMRAIAANFRDIMITLGMFTHDALLGGEGAGVVVEVG
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          LGSLGLEIAG----------------------------------------
MAB_0939|M.abscessus_ATCC_1997      LGSIGLEIAG----------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      LGAIGLEVAG----------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       LGALGLEVAE----------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        PGVTEFSVGDSVFGFFPDGSGTLVAGDVRLLLPMPADWSYAEAAAISAVF
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        TTAYYAFIHLADVQPGQRVLIHAGTGGVGMAAVQLARHLGLEVFATASKG
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        KWDTLRAMGFDDDHISDSRSLEFEDKFRAATGGRGFDVVLDSLAGEFVDA
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        SLRLVAPGGVFLEMGKTDIRDPGVIAQQYPGVRYRAFDLFEPGRPRMHQY
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        MLELATLFGDGVLRPLPVTTFDVRRAPAALRYLSQARHTGKVVMLMPGSW
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ---------------------YLAANGAGHLVLTSRRTPDEAAASRIEAL
MAB_0939|M.abscessus_ATCC_1997      ---------------------YLAGRGAKHLVLTSRREPGEAARQRIDAL
MSMEG_0408|M.smegmatis_MC2_155      ---------------------YLASHGAGHVVLTSRREPGDDARRRLDGL
Mvan_1003|M.vanbaalenii_PYR-1       ---------------------FLASHGAGHLVLTGRRSASDTVRQRIDAM
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        AAGTVLITGGTGMAGSAVARHVVARHGVRNLVLVSRRGPDAPGAAELVAE
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          RERHGCEVRVVTADVADAHAVARLLATVQAEMPPLAGIVHAAGEIGTTPL
MAB_0939|M.abscessus_ATCC_1997      AA-QGCEVRAVTADVADGHDVARLLAGIQAELPPLAGIVHAAGEIGTTPL
MSMEG_0408|M.smegmatis_MC2_155      REQYACDVRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPL
Mvan_1003|M.vanbaalenii_PYR-1       RERFDCQVLVATADVADRDDVARLFSTMRSELPPLAGIVHAAGEIGTSPL
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        LAAAGAQVQVVACDAADRAALAKVIADIPVQHP-LSGVIHTAGALDDAVV
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ADLDDAEVDRVFAGKVWGAWHLSEATSDLQ--LDFFISTSSIASVWGGFG
MAB_0939|M.abscessus_ATCC_1997      SDLEDAEVDRVFAGKVWGAWHLSEAAAGLK--LDFFINTSSIAAVWGGYG
MSMEG_0408|M.smegmatis_MC2_155      SGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSSIASVWGGFG
Mvan_1003|M.vanbaalenii_PYR-1       RTLDDAEMDRVFAGKVWGAVYLCEEVADMG--LDFFLATSSIASVWGSHG
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        MSLTPDRVDVVLRSKVDAAWHLHELTRDLD--VSAFVMFSSMAGLVGSSG
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          QAAYGAANAFLDGLAWRLREQGVAGVSVNFGPWSAG-----MADAQSRAR
MAB_0939|M.abscessus_ATCC_1997      QTAYSAANAFLDGLAWRLREQGIAGTSVNFGPWSAG-----MADAESRAR
MSMEG_0408|M.smegmatis_MC2_155      QTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWAAG-----MADAESRAR
Mvan_1003|M.vanbaalenii_PYR-1       QTAYGAANAFLDGLADSLRARGIPGISVNFGPWAAG-----MADAKAREQ
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        QANYAAANSFLDALAAHRRAHGLPAISLGWGLWDQASAMTGGLDAADLAR
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          LEQRGIKTLSPADALAGLSDAVISAAP---HPVVARVDWSRFLPLYQQAG
MAB_0939|M.abscessus_ATCC_1997      LEQRGIKTLSPTDALAGLADVVAASGSNAVQGVIARIDWARFLPLYQQAG
MSMEG_0408|M.smegmatis_MC2_155      LEQRGVRTLSPAEALAGMADVVAGPVQ----GVVAKIDWSRFLPLYQQAG
Mvan_1003|M.vanbaalenii_PYR-1       LSRRGVKTLAPADALAGMADVIAASTA---HAVVARIDWATFLPVYQLQR
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        LGREGVLALSTAEALELFDTAMIVDEP-----FLAPARIDLTALRAHAVA
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          RRGFLAELERELPAAPAQQGPAVTASGRTPLVERLTTAPLQQRKRLLTDY
MAB_0939|M.abscessus_ATCC_1997      KRGFLAELDREVPSHLA--GVAGAQSGSTQLVERLANAPVQQRKKLLTDY
MSMEG_0408|M.smegmatis_MC2_155      RRAFLSELESELPAAATGAAAPATVPGKPPLVEQLTKAPVQQRKSLITNY
Mvan_1003|M.vanbaalenii_PYR-1       RRAFLSQLEREVPDVPD--ASAPAPSGTTRFVEELTLAPVEQRRKLVLEY
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        VPPMFSDLASAPTRRQVDDSVAAAKSKSALAHRLHGLPEAEQHAVLLGLV
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          LRDAVAEVTRVDAAEIREDAGFFDLGMDSLMAVELRRRIETGVGKEIPVT
MAB_0939|M.abscessus_ATCC_1997      LRDAVAEVTRVDVSEIREDAGFFDLGMDSLMAVELRRRMEQGVGKEIPVT
MSMEG_0408|M.smegmatis_MC2_155      LRNAVAEVTRVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVT
Mvan_1003|M.vanbaalenii_PYR-1       LRAAVAEVTRVDAAEIRDEAGFFDLGMDSLMAIELRRRLEQGLGKELPVT
Mb2971c|M.bovis_AF2122/97           -----------------------------------------MIEEQRTMS
MLBr_00135|M.leprae_Br4923          ----------------------------------------------MTAS
MUL_2005|M.ulcerans_Agy99           ----------------------------------------------MTTS
MAV_3108|M.avium_104                --------------------------------------------------
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        RLHIATVLGNITPEAIDPDKAFQDLGFDSLTAVEMRNRLKSATGLSLSPT
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          LVMDHPRLSDAADYLLGDVLGLTEAAT-APKAATVVSTAADEPIAIVAVS
MAB_0939|M.abscessus_ATCC_1997      LVMDHPRISDVADYLLGDVLGLAEQAKPAAQLASAVTGRTDEPIAIVAVS
MSMEG_0408|M.smegmatis_MC2_155      LVMDHPRLSDAADYLLVEVLGLGEQTN--VRQASTVTARTDDPIAVVAVS
Mvan_1003|M.vanbaalenii_PYR-1       LAMDHPHLSDAAEYVLGDVLGLSEHTV--AQPDTPSTVRTDDPIAIVGMA
Mb2971c|M.bovis_AF2122/97           VEGADQQSEKLFHYLKKVAVELDETRA----RLREYEQRATEPVAVVGIG
MLBr_00135|M.leprae_Br4923          VEGADQKSEKLISYLKKVVVELDETRA----RLREYEQRATEPVAVVGIG
MUL_2005|M.ulcerans_Agy99           GESADQQNDKLFRYLKKVAVELDEARA----RLREYEQRATEPVAVVGIG
MAV_3108|M.avium_104                ----MPGTEQHLDYLKRLTADLRRTRR----RVAELEGRLSEPVAVVGMA
MMAR_3796|M.marinum_M               -------------------------------------------MAVVGMA
Rv2048c|M.tuberculosis_H37Rv        LIFDYPTPNRLASYIRTELAGLPQEIK----HTPAVRTTSEDPIAIVGMA
TH_2454|M.thermoresistible__bu      -----------------------------MSVDVTAKARPDDPIAIIGIG
                                                                               :*::.:.

Mflv_0405|M.gilvum_PYR-GCK          CRFPG-APNPEAFWDLLSGGVDAIREVPEDR-FDIDEFYDPDPDAAGKTY
MAB_0939|M.abscessus_ATCC_1997      CRFPG-APDPEAFWDVLSGGVDAIREVPEDR-FDIDEFYDPDPEVAGKTY
MSMEG_0408|M.smegmatis_MC2_155      CRFPG-APDPESFWELLAGGVDAIREVPEDR-WDIDEFYDPDPDTPGKTY
Mvan_1003|M.vanbaalenii_PYR-1       CRFPG-ADDTDAFWSVLAEGADLIREIPDDR-FDINEFYDPDPEAAGKIY
Mb2971c|M.bovis_AF2122/97           CRFPGGVDGPDGLWDVVSAGRDVVSEFPTDRGWDVEGLYDPDPDAEGKTY
MLBr_00135|M.leprae_Br4923          CRFPGGVDSPDRLWDVVSECRDVVSEFPTDRGWDVDGLFDPDPDAEGKTY
MUL_2005|M.ulcerans_Agy99           CRFPGGADGPEGLWDLVSQGRDAVTEFPNDRGWDTEGLFDPDPDAEGKTY
MAV_3108|M.avium_104                CRYAGGVDSPEALWDLVIEGRDTVSDFPVDRGWDVEGLYDPDPDAKGKMY
MMAR_3796|M.marinum_M               CRFPGGVDSPDGLWEMVSEGRDVVSELPLDRGWDLGRLYDPDPDRLGCVY
Rv2048c|M.tuberculosis_H37Rv        CRYPGGVNSPDDMWDMLIQGRDVLSEFPADRGWDLAGLYNPDPDAAGACY
TH_2454|M.thermoresistible__bu      CRLAGRITSPEEFWGFLLAGGSNVREIPAER-WEPYLRRDPRNAAVLREI
                                    ** .*   ..: :* .:    . : :.* :* ::     :*         

Mflv_0405|M.gilvum_PYR-GCK          TRYGGFLDHIDEFDPEFFGLSPREAVWIEPQQRLMLETVWEGLERAGYAP
MAB_0939|M.abscessus_ATCC_1997      TRFGGFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYSP
MSMEG_0408|M.smegmatis_MC2_155      TRFGGFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAP
Mvan_1003|M.vanbaalenii_PYR-1       SRYGGFLDGVDGFDPEFFGISPREAVWIDPQQRLVLETAWEGLERAGYSA
Mb2971c|M.bovis_AF2122/97           TRWGAFLDDATGFDAGFFGIAPSEVLAMDPQQRLMLEVSWEALEHAGIDP
MLBr_00135|M.leprae_Br4923          TRWGAFLDDAAGFDAGFFGIAPSEVLAMDPQQRLMLEVSWEALEYAGIDP
MUL_2005|M.ulcerans_Agy99           TRWGAFVENATNFDAGFFGIPPSEVLAMDPQQRLMLEVSWEALEHAGIDP
MAV_3108|M.avium_104                TRQGSFLQHAGDFDAGFFGIGPSEALAMDPQQRIMLEICWEALERAGIDP
MMAR_3796|M.marinum_M               TRGGGFLSGVADFDAGFFGISPREALGMDPQQRLMLEIAWETFESAGIDP
Rv2048c|M.tuberculosis_H37Rv        TRTGGFVDGVGDFDPAFFGVGPSEALAMDPQHRMLLELSWEALERAGIDP
TH_2454|M.thermoresistible__bu      TPWGTFLDDLAGFDAEFFGVSPREAELTDPQQRLALEVSWEALEHAGVPP
                                    :  * *:.    **. ***: * *.   :**:*: **  ** :* **  .

Mflv_0405|M.gilvum_PYR-GCK          SALRGSRTGVFVGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAF
MAB_0939|M.abscessus_ATCC_1997      AALRGSRTGIFAGVGANEYAHLLSSESIDKIEPYFITGNALNAISGRVAF
MSMEG_0408|M.smegmatis_MC2_155      SDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAF
Mvan_1003|M.vanbaalenii_PYR-1       AALRGSRSGVYVGVGANEYSHLLSGGSLDGIEAQFITGNALNVIAGRVSF
Mb2971c|M.bovis_AF2122/97           LSLRGSATGVYTGIFAASYGNRDT----GGLQGYGLTGTSISVASGRVSY
MLBr_00135|M.leprae_Br4923          LSLRGSATGVFTGIFAPSYGSRDT----GGLQGYGLTGTAVSVASGRVSY
MUL_2005|M.ulcerans_Agy99           MSLRGSSTGVFTGIFAPSYGGKDV----GALQGYGLTGSPVSVASGRVAY
MAV_3108|M.avium_104                SALRGTATGVFAGVIHAGYGGEVK----GELEGYGLTGSTLSVTSGRVSY
MMAR_3796|M.marinum_M               HSLRGSQTGVFAGVMSSHYEEIGG----DQAEGCLAVGTEASVVSGRVAF
Rv2048c|M.tuberculosis_H37Rv        TGLRGSATGVFAGVMTQGYGMFAA----EPVEGFRLTGQLSSVASGRVAY
TH_2454|M.thermoresistible__bu      RSLAGTDTAVLMGVNSDDYGRLLMED-LPGIEAWTGIGTSLCGIANRVSH
                                      * *: :.:  *:    *            :     *      :.**:.

Mflv_0405|M.gilvum_PYR-GCK          ALGLEGPAVAVDTACSSSLVAVHQATQALRSGDCDMALAGGVNVLLSPVT
MAB_0939|M.abscessus_ATCC_1997      ALGFEGPAVAVDTACSSALVAVHQAVQALHSGDCDLALAGGVNVLLSPVT
MSMEG_0408|M.smegmatis_MC2_155      ALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVT
Mvan_1003|M.vanbaalenii_PYR-1       TLGLEGPAVAVDTACSSSLVAVHQACQGLQSGDCDLALAGGVNVLLSPAT
Mb2971c|M.bovis_AF2122/97           VLGLQGPAVSVDTACSSSLVAIHWAMSSLRSGECDLALAGGVTVMGLPSI
MLBr_00135|M.leprae_Br4923          VLGLEGPAVSVDTACSSSLVAIHWAMSSLRSGECDLALAGGVTVMGLPSI
MUL_2005|M.ulcerans_Agy99           VLGLEGPALSVDTACSSSLVAIHWAMASLRSGECDMALAGGVTVMGLPSI
MAV_3108|M.avium_104                VLGLEGPAVSVDTACSSSLVAMHLAAQSLRSGECDLALAGGVTVMATPAA
MMAR_3796|M.marinum_M               TFGLEGPAVSVDTACSSSLVAIHQAGQSLRGGECSMALAGGVMVMAVPST
Rv2048c|M.tuberculosis_H37Rv        VLGLEGPAVSVDTACSSSLVALHMAVGSLRSGECDLALAGGVTVNATPDI
TH_2454|M.thermoresistible__bu      LLDLRGPSVALDAACAASLVAVHNACQLLRAGETGLAIAGGVSALIGPGL
                                     :.:.**::::*:**:::***:* *   *:.*: .:*:**** .   *  

Mflv_0405|M.gilvum_PYR-GCK          VVAASRARMLSPVGRCKTFDASADGYVRSEGCGILVLKRLSDAVRDGDRV
MAB_0939|M.abscessus_ATCC_1997      VIAASRARMLSPVGRCKTFDASADGYVRSEGCGILVLKRLSDAERDGDRV
MSMEG_0408|M.smegmatis_MC2_155      VVAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRV
Mvan_1003|M.vanbaalenii_PYR-1       TIATSRARMLSPDGRCKTFDAAADGYVRGEGCGILVLKRLSDAVRDGDRI
Mb2971c|M.bovis_AF2122/97           FVGFSRQRGLAADGRCKAFAAAADGTGWGEGAGVVVLERLSDARRLGHSV
MLBr_00135|M.leprae_Br4923          FVGFSRQRGLAADGRCKAFARAADGTGWGEGAGVVVLERLSDAQRLGHTV
MUL_2005|M.ulcerans_Agy99           FVGFSRQRGLAADGRCKAFAAAADGTGWGEGAGVLVLERLSDAQRNGHNV
MAV_3108|M.avium_104                FVEFSRQRALAPDGRCKVYAGAADGTSWSEGAGVLVLERLADARRLGHPV
MMAR_3796|M.marinum_M               LVEFSRKRGLSPDGRCRSFAAAADGTGFAEGAGLVLLERLSDARRHGHQV
Rv2048c|M.tuberculosis_H37Rv        FVEFSRWRGLSPDGRCKAFAAAADGTGFSEGGGMLVLQRLSDARRLGHPV
TH_2454|M.thermoresistible__bu      TRVLDKAGATAPDGRCKSFDASADGYGRGEGAAVVILKRLPDALRDGDRV
                                        .:    :. ***: :  :***   .** .:::*:**.** * *. :

Mflv_0405|M.gilvum_PYR-GCK          CAVIAGSAVNQDGASSGLTVPNGGAQQRLIGTVLARAGITGGEVDYLEAH
MAB_0939|M.abscessus_ATCC_1997      LAVIPGSAVNQDGASSGLTVPNGGAQQRLIGSVLARAGLVGGDVDYLEAH
MSMEG_0408|M.smegmatis_MC2_155      CAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAH
Mvan_1003|M.vanbaalenii_PYR-1       QAVIRGSAVNQDGASGGLTVPNGGAQQRVIAAALTRAGLSGSDIDYLEAH
Mb2971c|M.bovis_AF2122/97           LAVVRGSAVNQDGASNGLTAPNGLAQQRVIQAALANAGLSAADVDVVEAH
MLBr_00135|M.leprae_Br4923          LAVVRGSAVNQDGASNGLTAPNGLAQQRVIQAALTNAGLSSADVDVVEAH
MUL_2005|M.ulcerans_Agy99           LAVVRGSAINQDGASNGLTAPNGLTQQRVIQAALANCGLTSADVDVVEAH
MAV_3108|M.avium_104                WAVLRGSAVNQDGASNGLTAPNGPSQQRVIRAALANAGLSAVDVDVVEGH
MMAR_3796|M.marinum_M               LAVIRGSAINQDGASKRLTAPNGRAQERVIRSALTAAGLEVADVDVVEAH
Rv2048c|M.tuberculosis_H37Rv        LAVVVGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGH
TH_2454|M.thermoresistible__bu      IAVIRGGAVAQDGRTVGIMSPNGAAQRDLFRHTCEITGTSPATVDFVEAH
                                     **: ..:: *** :  :  *** :*. :.  .    *     :* :*.*

Mflv_0405|M.gilvum_PYR-GCK          GTGTPLGDPIEVQAAAAAYAGAR-DADRPLLMGSVKTNIGHTESASGAAG
MAB_0939|M.abscessus_ATCC_1997      GTGTPLGDPIEVQAAAAAYGGSR-DADRPLLMGSVKSNIGHTESASGAAG
MSMEG_0408|M.smegmatis_MC2_155      GTGTPLGDPIEVQAAAAAYGAGR-DADRPLLMGSVKTNIGHTESASGAAG
Mvan_1003|M.vanbaalenii_PYR-1       GTGTSLGDPIEVQAAGAVLGAGR-DPDRPLLMGSVKTNVGHLESASGVAG
Mb2971c|M.bovis_AF2122/97           GTATTLGDPIEAQALLSTYGQGR-PAEQPLWVGSIKSNMGHTQAAAGVAG
MLBr_00135|M.leprae_Br4923          GTATTLGDPIEAQALLATYGQGR-PADQPLWVGSIKSNMGHTQAAAGVAG
MUL_2005|M.ulcerans_Agy99           GTATTLGDPIEAEALLATYGQGR-PTDQPLWVGSIKSNMGHTQAAAGVAG
MAV_3108|M.avium_104                GTGTVLGDPIEAQALLATYGQDR-PADRPLWLGSIKSNIGHTSAAAGVAG
MMAR_3796|M.marinum_M               GTGTLKGDPIEAHAILATYGQDR-PADRPLWLGSVKSNMGHTQAAAGVAG
Rv2048c|M.tuberculosis_H37Rv        GTGTTLGDPIEAQALLATYGQDRGEPGEPLWLGSVKSNMGHTQAAAGVAG
TH_2454|M.thermoresistible__bu      GTGTPTGDPVELDALAAVYGAAH-GPDDPCRVGSVKPNTGHLEGGAGVVG
                                    **.*  ***:* .*  :. .  :  .  *  :**:*.* ** ...:*..*

Mflv_0405|M.gilvum_PYR-GCK          LIKVVLSLQHETLPQSLHFDTPSPHIPWDSLPVRVVDTAMPWQPN-GRPR
MAB_0939|M.abscessus_ATCC_1997      LIKVVLSLQNGVLPQSLHFDNPSPHIPWESLPVRVVDKAIPWQAN-GRPR
MSMEG_0408|M.smegmatis_MC2_155      LIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTN-GRVR
Mvan_1003|M.vanbaalenii_PYR-1       LIKVVLSLQHEMLPRHLHFKTPSPHIPWDRLAVRVVAEPTPWRAD-GRPR
Mb2971c|M.bovis_AF2122/97           VIKMVQAMRHGVMPATLHVDEPSPRVDWTSGAVSVLTEAREWSVD-GRPR
MLBr_00135|M.leprae_Br4923          VIKMVQAMRHHVMPATLHVDEPSPRVDWTTGAVSVLTEARDWSVE-GRPR
MUL_2005|M.ulcerans_Agy99           VIKMVQAMRHGLMPASLHVDEPSKRVDWESGAVSVLAEARDWPDA-GRPR
MAV_3108|M.avium_104                VIKMVQALRHGVMPKTMHVDVPSPHVDWSAGAVSLLTDPRPWPEH-GGPR
MMAR_3796|M.marinum_M               VIKMIQAMRHQVMPRSLHVDSPSPRVDWASGAVELLTEQRDWTVQDGRLR
Rv2048c|M.tuberculosis_H37Rv        VIKMVLAMRHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWPAG-ARTR
TH_2454|M.thermoresistible__bu      LIKAALALQHGVIPPTAGIRELTPAVDWATNGLHVPTTVEPFPRRADSPR
                                    :**   ::::  :*    .   :  : *    : :      :       *

Mflv_0405|M.gilvum_PYR-GCK          RAGVSSFGFTGTNAHVLIEEAPTDLAGPTEPTAPAEPVDEDAAADPAPAP
MAB_0939|M.abscessus_ATCC_1997      RAGVSSFGFTGTNAHVLIEEAPQPQATP----------DEDDASTPQSAP
MSMEG_0408|M.smegmatis_MC2_155      RAGVSSFGFTGTNAHVLVEEAPPQLHTADAAP----VEPAATAEAGTDDS
Mvan_1003|M.vanbaalenii_PYR-1       RAGVSSFGFSGTNAHVVLEEPPAQSADLRQPPTDGKDGAAGLESATAPEP
Mb2971c|M.bovis_AF2122/97           RAAVSSFGISGTNAHLILEEAPVPAPAE------APVEASESTGGP-RPS
MLBr_00135|M.leprae_Br4923          RAGVSSFGISGTNAHVILEEAPT------------PVEASYSTADQQRLS
MUL_2005|M.ulcerans_Agy99           RAGVSSFGISGTNAHVILEEAPAP----------EAVPDSESNKGEPSLP
MAV_3108|M.avium_104                RAGVSSFGISGTNAHVIVEQAPAA-----------AETEAAPASSTMPDA
MMAR_3796|M.marinum_M               RAGVSSFGISGTNAHVILEEAPAW----------SAPGHGGDSGAASPWP
Rv2048c|M.tuberculosis_H37Rv        RAGVSSFGISGTNAHVIIEAVPVV----------PRR----EAGWAG--P
TH_2454|M.thermoresistible__bu      RAAVCSYGYGGTIAHLLLEEAPAVDETP-----AAAPAPAADAADANSPR
                                    **.*.*:*  ** **:::*  *                            

Mflv_0405|M.gilvum_PYR-GCK          VEVLPLSARSPEALVALAQRYETWLTAHPEADLADVCRTAGTGRSHFEHR
MAB_0939|M.abscessus_ATCC_1997      VSVLPLSARSPEALAAVAQRYESWLAAHPDVDLEDVCLTAGRGRSHFEHR
MSMEG_0408|M.smegmatis_MC2_155      PQVLALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYR
Mvan_1003|M.vanbaalenii_PYR-1       AGVLPISARSPEALTALARRYESWLTAHPDADIADVCYTAGAGRSHFEHR
Mb2971c|M.bovis_AF2122/97           MVPWVISARSAEALTAQAGRLMAHVQANPGLDPIDVGCSLAS-RSVFEHR
MLBr_00135|M.leprae_Br4923          VVPWVVSGRSTAALMAQASRLAFYVQADPEVDPVDVGCALAA-RSVFEHR
MUL_2005|M.ulcerans_Agy99           VVPWVISARSAEALTAQAGRLLAHVQADPQSNPVDIGFSLAG-RSAFEHR
MAV_3108|M.avium_104                VVPWVVSARSAEALAGQARRLLDHVTADAQASPLDVGWSLVSTRAVFEHR
MMAR_3796|M.marinum_M               AVPWVVSGKSGQALAAQAGRLAGHLSADDDIDVLGVGWSLAQ-RSMFEHR
Rv2048c|M.tuberculosis_H37Rv        VVPWVVSAKSESALRGQAARLAAYVRGDDGLDVADVGWSLAG-RSVFEHR
TH_2454|M.thermoresistible__bu      FHVIPVSARSGARLARHAAALRGHLSAG--ADLTAVAATMWQRRSHEPVR
                                         :*.:*   *   *      : .    .   :  :    *:    *

Mflv_0405|M.gilvum_PYR-GCK          AALVVDSVESARIALTDLAQNRLRPGVVRGEHLNHPTT--AWMFTGQGSQ
MAB_0939|M.abscessus_ATCC_1997      AALVVDSIQTAREGLLELAQNRLRPGVVRGEHTNHPTT--AWLFTGQGSQ
MSMEG_0408|M.smegmatis_MC2_155      AALVVDSVERAREGLAALAEGRTPAGVVRGEHVHRPTT--AWLFTGQGSQ
Mvan_1003|M.vanbaalenii_PYR-1       AALVVDSVDGARDLLAGLAEDRLGPGAVRGVCGDPPKT--AWLFTGQGSQ
Mb2971c|M.bovis_AF2122/97           AVVVGASREQLIAGLAGLAAGEPGAGVAVGQPGSVGKT--VVVFPGQGAQ
MLBr_00135|M.leprae_Br4923          AVVVGESREQLIAGLAGLAVGESGAGVAIGQAAPLGKT--VVVFPGQGAQ
MUL_2005|M.ulcerans_Agy99           AVVVGADRQQLLTGLATLADGAPGAGVVTGQAGSVGKT--AVVFPGQGSQ
MAV_3108|M.avium_104                AVVVGRERGALATGLAGLASGRPGPATVVGRARSTGKT--VLVFPGQGSQ
MMAR_3796|M.marinum_M               AVVFGAGREELLSGLADLAQGRPAGAVLTGHAHVAGKT--ALVFPGQGAQ
Rv2048c|M.tuberculosis_H37Rv        AVVVGGDRDRLLAGLDELAGDQLGGSVVRGTATAAGKT--VFVFPGQGSQ
TH_2454|M.thermoresistible__bu      AAVIARHPGELVAGLDAIATDTRHPAVVAGSVLPAAEAGAVWVFSGHGSH
                                    *.:.          *  :* .    ..  *       :  . :*.*:*::

Mflv_0405|M.gilvum_PYR-GCK          YPGMARELFDTEPVFADTVTRCADAVADLLPRPLLDVMFAGGREAGVPPT
MAB_0939|M.abscessus_ATCC_1997      YPGMARELFDAEPVFAETVTRCAEAVKDIVTRPLLEVMFATDRETGGKAG
MSMEG_0408|M.smegmatis_MC2_155      YPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRET----A
Mvan_1003|M.vanbaalenii_PYR-1       YPGMARELFDTEPVFRDTVTRCAEAIGDTLPRPLLEVLFDTDGDN----G
Mb2971c|M.bovis_AF2122/97           RIGMGRELYGELPVFAQAFDAVADELDRHLRLPLRDVIWGA-------DA
MLBr_00135|M.leprae_Br4923          RIGMGRELCSQLPVFAEEFDAVTGELDRHMRLPLRDVVWGA-------DA
MUL_2005|M.ulcerans_Agy99           RIGMARELHDQLPVFAEAFDAVADELDRHLRIPLCEVMWGS-------DV
MAV_3108|M.avium_104                TLGMGRQLYERFEVFAGALDEAVAVVDEHSRLSVREVMWGA-------DP
MMAR_3796|M.marinum_M               WLGMGQQLHAQFPIFAAAFDAVAGELDQHLRMSLQSVLWGD-------NQ
Rv2048c|M.tuberculosis_H37Rv        WLGMGMGLHAGYPVFAEAFNTVVGELDRHLLRPLREVMWGH-------DE
TH_2454|M.thermoresistible__bu      WPGMGRELLEHEPVFAAVIDEIEPVFRAELGFSPRQALQSG---------
                                      **.  *     :*   .      .      .  ..:            

Mflv_0405|M.gilvum_PYR-GCK          ETLRHTSFAQPALFAVEMGLARLWQSWGIVPDVVLGHSVGQYAAACVAGV
MAB_0939|M.abscessus_ATCC_1997      EALRHTSFAQPALFAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVAGV
MSMEG_0408|M.smegmatis_MC2_155      DLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGV
Mvan_1003|M.vanbaalenii_PYR-1       QTLRHTSYAQPALFAIEMGLARLWQARGIEPDVVLGHSVGQYAAACVAGV
Mb2971c|M.bovis_AF2122/97           DLLDSTEFAQPALFAVEVASFAVLRDWGVLPDFVMGHSVGELAAAHAAGV
MLBr_00135|M.leprae_Br4923          GLLDSTEFAQPALFAVEVALFAVLQHWGLQPDFVMGHSIGELAAAYVAGV
MUL_2005|M.ulcerans_Agy99           ALLDSTEFAQAALFAVEVALFAALQRWGLQPDFVMGHSVGELSAAYVAGV
MAV_3108|M.avium_104                ELLQSTEFAQPALFVFEVALAALWESLGVTPDVVMGHSVGEIAAACVAGV
MMAR_3796|M.marinum_M               ALLNSTEFAQPALFAVEVAMLQLLRHWGIRPDFVLGHSVGEIAAAYAAQV
Rv2048c|M.tuberculosis_H37Rv        NLLNSTEFAQPALFAVEVALFRLLGSWGVRPDFVMGHSIGELSAAHVAGV
TH_2454|M.thermoresistible__bu      -ELGGTDRVQALTFAVQAGLAAVLRDRGVKPAAVIGHSVGEVAACVAAGV
                                      *  *. .*.  *..: .        .: *  *:***:*: :*. .* *

Mflv_0405|M.gilvum_PYR-GCK          FSLEDGARLMAERGRLFGSLPEGGRMVAVFADAKRVEQVAADFPRVSVGA
MAB_0939|M.abscessus_ATCC_1997      FSIEDGARLIAERGRLFGGLPAGGRMVAVFSDAKHVEQIAGEFPRVSVGA
MSMEG_0408|M.smegmatis_MC2_155      FSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGA
Mvan_1003|M.vanbaalenii_PYR-1       FGLEDGARLVADRGRLFGGLPVGGRMVAVFTDAEVVEDFADEFPQVSVAA
Mb2971c|M.bovis_AF2122/97           LTLADAAMLVVARGRLMQALPAGGAMVAVAASEDEVEPLLGEG--VGIAA
MLBr_00135|M.leprae_Br4923          LAPADAAMLVVARGRLMQSMPAGGTMWAVAASEDEVVSLLGEG--VGIAA
MUL_2005|M.ulcerans_Agy99           LTLVDAAMLVVARGRLMQALPAGGAMVAVAAAEDEVLPSLTDG--VGIAA
MAV_3108|M.avium_104                LSLRDAARLVAARGALMAALPPGGVMVAVTAGESQVGPLLGGG--VSIAA
MMAR_3796|M.marinum_M               LSLSDAALVVAARGRLMQSLPAGGVMFAVAATEDEVTPQLVDG--AGIAA
Rv2048c|M.tuberculosis_H37Rv        LSLENAAVLVAARGRLMQALPAGGAMVAVQAAEEEVRPLLSAE--VDIAA
TH_2454|M.thermoresistible__bu      FDLARGAAVACYRARGFRSVAGKGAMALVGLPFEDARQRLGERTDVVAAI
                                    :    .* :   *.  : .:.  * *  *    . .         .  . 

Mflv_0405|M.gilvum_PYR-GCK          YNGP-NTVLSGPGEDLEQIVGTFGEDGIRCTWLETSHAFHSELLDPVLDE
MAB_0939|M.abscessus_ATCC_1997      YNGP-NTVLSGPGEDLEQAVARFQEEGIRCTWLETSHAFHSELLDPILDE
MSMEG_0408|M.smegmatis_MC2_155      YNGP-NTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDE
Mvan_1003|M.vanbaalenii_PYR-1       YNGP-NTVLAGPASDLEQIVAGCSGEGIRTTWLDTSHAFHSALLDPVLDE
Mb2971c|M.bovis_AF2122/97           INAPESVVISGAQAAANAIADRFAAQGRRVHQLAVSHAFHSPLMEPMLEE
MLBr_00135|M.leprae_Br4923          INAPESVVISGPQAAVSAIADKFAAQGRRVHQLAVSHAFHSPLMEPMLEE
MUL_2005|M.ulcerans_Agy99           INAPKSVVISGAEAAVTAISDQFAQQGRRVHRLAVSHAFHSPLMEPMLEE
MAV_3108|M.avium_104                VNGPDAVVLSGEQEAVAAVADRLAGSGARVHRLAVSHAFHSALMEPMLDG
MMAR_3796|M.marinum_M               INAPGSVVISGTQEAVTPIVNDFHGRGRRVHQLAVSHAFHSPLVEPILDE
Rv2048c|M.tuberculosis_H37Rv        VNGPASLVISGAQNAVAAVADQLRADGRRVHQLAVSHAFHSPLMDPMIDE
TH_2454|M.thermoresistible__bu      SASPLSTVISGTVDAVGEVSAAWAEQGVMVRKVNTDVAFHSPAMDALTAE
                                      .*   *::*               *     : .. ****  ::.:   

Mflv_0405|M.gilvum_PYR-GCK          FESYAAQLQFAAPTLPLVCNRTGAVLTGQT-SLDAQYWRRHSRQPVQFAE
MAB_0939|M.abscessus_ATCC_1997      FESYAAQVQFAAPTLPLVCNRTGAVLTAQT-PIDGQYWRRHSRQPVQFAE
MSMEG_0408|M.smegmatis_MC2_155      FEAYAAQFQFAAPTLPLVCNRTGAVLTGQT-PLDAQYWRRHSRQPVQFAE
Mvan_1003|M.vanbaalenii_PYR-1       FESCAARLAYAAPTRPLVCNRTGAVVTGPG-VIDAQYWRRHARQPVQFAE
Mb2971c|M.bovis_AF2122/97           FARVAARVQAREPQLGLVSNVTGELAGPD--FGSAQYWVDHVRRPVRFAD
MLBr_00135|M.leprae_Br4923          FVRVAAQVEVRKPQIGLVSNVTGELAGPD--FGSPQYWGEHVSRAVRFVD
MUL_2005|M.ulcerans_Agy99           FARIAAQVEAREPQIALVSNVTGELASADGGFGSAQYWVEHVRRAVRFAD
MAV_3108|M.avium_104                FAAAAAGIEPRPPRIPLVSNLTGQLAGPG--YGTPQYWVDHVRRPVRFVD
MMAR_3796|M.marinum_M               FGSAISGITVGEPTISVVSNVTAALGGPE--YGSPQYWVDHVRQPVRFAD
Rv2048c|M.tuberculosis_H37Rv        FAAVAAGIAIGRPTIGVISNVTGQLAGDD--FGSAAYWRRHIRQAVRFAD
TH_2454|M.thermoresistible__bu      LARLTSTLTPKPAAVPLYSTALADPRSTAA--RDEHYWVANLRGRVRFAE
                                    :    : .    .   : ..  .             **  :    *:*.:

Mflv_0405|M.gilvum_PYR-GCK          SVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHLAAPRAIA-SLRKGVAD
MAB_0939|M.abscessus_ATCC_1997      SVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHLAPPRAIV-SLRKGVED
MSMEG_0408|M.smegmatis_MC2_155      SVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVA-SLRKGVAD
Mvan_1003|M.vanbaalenii_PYR-1       SVRTLADLGCSVLMEIGPQPFLIAAALRVWPESAATPRAIP-SLRKGPDA
Mb2971c|M.bovis_AF2122/97           SARHLQTLGATHFIEAGPGSGLTGSIEQSLAPAEAMVVS---MLGKDRPE
MLBr_00135|M.leprae_Br4923          SARHLQTLGATHFIESGPSSGLMGAIEQSLAPAEAVVVS---MMGKDRPE
MUL_2005|M.ulcerans_Agy99           SARQLHTLGVTHFVEVGPGSGLTGSIEQSLAPAEAVVVS---MLGKDRPE
MAV_3108|M.avium_104                GVRLAESQGAGVFLEVGPGAALTSAVEQSLTSDRAMSVV---TMPKGRPE
MMAR_3796|M.marinum_M               SVRLLESMGATRFVEVGPGAGLSTSVEQSLASPEDVVVIP--VLGKQRPE
Rv2048c|M.tuberculosis_H37Rv        SVRFAQAAGGSRFLEVGPSGGLVASIEESLP-DVAVTTMS--ALRKDRPE
TH_2454|M.thermoresistible__bu      AVTAAAEDGHRLFLEVSAHPVVCHSMAETLALAEVGEHAVLPVLRREQPE
                                    ..      *   ::* ..   :  :  .  .            : :    

Mflv_0405|M.gilvum_PYR-GCK          RRQIADALAAAYIGGHKPDFAALHEQ-RGVRLELPTYPFQRRRFWPK---
MAB_0939|M.abscessus_ATCC_1997      RRQIADALASAYVSGHRPNFAALQRH-PRRTVELPTYPFQRRRFWPK---
MSMEG_0408|M.smegmatis_MC2_155      RRQIADALASAYVGGHRPDFAAVHRQ-PRRPVELPTYPFQRRRFWPK---
Mvan_1003|M.vanbaalenii_PYR-1       RRQLAEAVAAAYIAGHRLDFTGHDGG-PHRRLPLPTYPFQHRSYWPK---
Mb2971c|M.bovis_AF2122/97           LASALGAAGQVFTTGVPVQWSAVFAGSGGRRVQLPTYAFQRRRFWETPGA
MLBr_00135|M.leprae_Br4923          LASVLGAAGQLFATGMPVEWPAVFAGSSRRRVTLPTYAFQRRRFWETPGT
MUL_2005|M.ulcerans_Agy99           VASVLTAFGQLFSTGMSVDWPAVFAGSGATRVDLPTYAFQRRRFWEVPGA
MAV_3108|M.avium_104                VDSLLTAAARLFTAGADVRWSAAFTGLHARRVDLPTYAFARRRFWLSGDA
MMAR_3796|M.marinum_M               GSSALHAAAVLFTTGATLDWSAVFDHTPAQRITLPTYAFQRRRFWLD-GT
Rv2048c|M.tuberculosis_H37Rv        PATLTNAVAQGFVTGMDLDWRAVVG--EAQFVELPTYAFQRRRFWLS-GD
TH_2454|M.thermoresistible__bu      LPAVAAVVGALYCHGAPVRP--AFPPGTRWATGLPGTQWQHRRFWRT--P
                                          . .  :  *                  **   : :* :*     

Mflv_0405|M.gilvum_PYR-GCK          SAGMAIDGRVGASAGSGILGSGKD-LASGDSVYTSRLSVKTQPWLSDHVI
MAB_0939|M.abscessus_ATCC_1997      SSGTAIEG--GGGLPSGILGRGED-LASGDSVYISRLSVRSQPWLSDHVI
MSMEG_0408|M.smegmatis_MC2_155      ASSIAVDG---GTAASGILGSGKD-LASGDTIYTSRLSVKSQPWLADHVI
Mvan_1003|M.vanbaalenii_PYR-1       TAGIRSDG----SSGSGLLGSAQD-LASGDIVHTSRLSVKTQPWLSDHVI
Mb2971c|M.bovis_AF2122/97           DGPADAAGLGLGATEHALLGAVVERPDSDEVVLTGRLSLADQPWLADHVV
MLBr_00135|M.leprae_Br4923          DGTASVSGLGLGSTEHALLGAVVERPDSGGVVLTGRLSLANQPWLADHVI
MUL_2005|M.ulcerans_Agy99           DGPADATGLGLGGAEHALLGAVVERPDSGGVVLTGRLALADQPWLADHVI
MAV_3108|M.avium_104                VGSANIASLGLAEAEHPLLGAVLDRPDSGGVVLTGRLSTAAQPWLADHAV
MMAR_3796|M.marinum_M               SRAGDVGNVGLAAVAHALLGAVITQPDSGGVILTGLLTPRTQPWLADHRI
Rv2048c|M.tuberculosis_H37Rv        GVAADAAGLGLAASEHALLGAVIDLPASGGVVLTGRLSPSVQGWLADHSV
TH_2454|M.thermoresistible__bu      GTPPGGVGVHDVDSHTLLGGRIDVAGAVPARVWQTRLDLSTRPYPGDHPV
                                           .         : *           :    *    : : .** :

Mflv_0405|M.gilvum_PYR-GCK          YGTVVVPGATYAAMALAAVGTP--AHAKDVFFYEPIILPEKSSREVQLTV
MAB_0939|M.abscessus_ATCC_1997      YGTVVVPGATYAAMALAAVGTP--ARAKDVFFYEPIILPEKSSREVQLTL
MSMEG_0408|M.smegmatis_MC2_155      YGTVVVPGATYAAMALAAVGTP--ARLKDVFFYEPIILPEKASREVQLTL
Mvan_1003|M.vanbaalenii_PYR-1       YGTVVVPGATYAAMALAAMPTP--ARVQEVFFYEPIILGDKDSREVQLML
Mb2971c|M.bovis_AF2122/97           NGVVLFPGAGFVELVIRAGDEVGCALIEELVLAAPLVMHPGVGVQVQVVV
MLBr_00135|M.leprae_Br4923          GGVVLFPGAGFVELVIRAGDEVGCAGVEELVLAAPLVLHPGSGVQVQVVV
MUL_2005|M.ulcerans_Agy99           GGVVLFPGAGFVELAIRAGDEVGCAVVEELVLAAPLVLHPGMGVQVQVIV
MAV_3108|M.avium_104                AGTVLFPGAGFVELALRAGDEVGCPVVEELTLSAPLSLPAGGTVQLQVVV
MMAR_3796|M.marinum_M               AGVMLFPGAGFVELAIRAGDEVNCPVLHELTLMAPLAISESG-VPVQVMV
Rv2048c|M.tuberculosis_H37Rv        AGVTIFPGAGFVELAIRAGDEVGCGVVDESTLAAPLVLPASGSVAVQVVV
TH_2454|M.thermoresistible__bu      QGTEIVPAAVLLNTFLTAAGSD----IADVRLRTPVAPARTRDVQVVLQD
                                     *. :.*.*      : *          :  :  *:         : :  

Mflv_0405|M.gilvum_PYR-GCK          HPSVDGE-SKFQVHSRPYGERGAEWALNAEGVVASGVGD---SPAAAGDL
MAB_0939|M.abscessus_ATCC_1997      HPLEDGSGSKFQVHSRPYGERDVDWSLNAEGTVVTGIGDDAEPAPEAAEP
MSMEG_0408|M.smegmatis_MC2_155      HPADGGSVLSFQIHSRPYGERGADWSLNAEGTVDTAGSD---PDAAADEQ
Mvan_1003|M.vanbaalenii_PYR-1       HRTDDADGWTFEVHSRPYGDRDADWSRNASGTVAAGVGD-----AAPDAA
Mb2971c|M.bovis_AF2122/97           G-AADESGHRAVSVYSRGDQSQG-WLLNAEGMLGVAAAET---------P
MLBr_00135|M.leprae_Br4923          A-AADESSRRAVSVYSRGDQSHGGWLLNAEGLLEVDAAEA---------T
MUL_2005|M.ulcerans_Agy99           G-TADDSGNRALSVYSRGDKSED-WLLNAEGMLGVEAASS---------G
MAV_3108|M.avium_104                ADAAGQPGSRSVAVYSR--VAQSEWTLHAEGVLSEAAPAP---------A
MMAR_3796|M.marinum_M               G-AAGESGSRTVAVYSAEGQSDSEWILHAKGVLTVGTAEPS------LMS
Rv2048c|M.tuberculosis_H37Rv        N-GPDESGVRGVSVYSR-GDVGTGWVLHAEGALRAGSAEP---------T
TH_2454|M.thermoresistible__bu      R-----------------------ALALASRIVGEDTTAR---------A
                                                                *.  :                 

Mflv_0405|M.gilvum_PYR-GCK          EDPVDEAIERLNRMRPQELFETFADLELAWGPTWSGSLKSLWLGEGEAIG
MAB_0939|M.abscessus_ATCC_1997      AEPVDAAIERMERMRPMELFEIFADLELAWGPTWSGSLKSLWLGEGEAIG
MSMEG_0408|M.smegmatis_MC2_155      SDPVDEVIERLERMRPQDLFETFADLELAWGPTWSGSLKSLWLGDGEAVG
Mvan_1003|M.vanbaalenii_PYR-1       ADPVDNAIERLTRTRPQQLFDAFADNDLAWGPAWCSSLRSLWVGTGEAVG
Mb2971c|M.bovis_AF2122/97           MDLSVWPPEGAESVDISDGYAQLAERGYAYGPAFQG-LVAIWRRGSELFA
MLBr_00135|M.leprae_Br4923          VDLSLWPPEGAESVDISDAYPQLAERGYAYGPAFQG-LVAIWRRGSELFA
MUL_2005|M.ulcerans_Agy99           ADLSVWPPEGAESVDISDGYAQLADRGYAYGPGFQG-LVGVWRRDSELFA
MAV_3108|M.avium_104                AELSVWPPADAEAVDVAGGYDDLAGRGYGYGPAFRG-LRAVWRRGAETFA
MMAR_3796|M.marinum_M               SELSAWPPAGAEVLDIAGGYDRLAGLGYQYGPAFQG-LTAVWKRGEDVFA
Rv2048c|M.tuberculosis_H37Rv        ADLAMWPPAGAVPVEVADGYQQLAERGYGYGPAFRG-LTAMWRRGDEVFA
TH_2454|M.thermoresistible__bu      TAGRDTTDRDTTACDTTDRDTTACDDPGVWLTHCTARVADDHVGAEGVLD
                                                           .     : .   . :          . 

Mflv_0405|M.gilvum_PYR-GCK          DILVGAELAEQLGTEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLYLPL
MAB_0939|M.abscessus_ATCC_1997      DVLVGEELAEQLGTEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLFLPL
MSMEG_0408|M.smegmatis_MC2_155      DILVGAELAEQLGSEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLFLPL
Mvan_1003|M.vanbaalenii_PYR-1       DIAVGAELGEHLGREPIHPVLLDLCTGIAGAALLAAAAQTDADPELFLPL
Mb2971c|M.bovis_AF2122/97           EVVAPGEAGVAVDRMGMHPAVLDAVLHALGLA----VEKTQASTETRLPF
MLBr_00135|M.leprae_Br4923          EVVAP--TGVVVDGMGMHPALLDAVLHALGLA----IENTQATTEMRLPF
MUL_2005|M.ulcerans_Agy99           EVVAP--SGVAVDKMGMHPVVLDAVLHALGLT----AEQNPDSDETKLPF
MAV_3108|M.avium_104                EVELPEQAGVSTGRFGIHPVLLDAALHALGVA----DKR----LETVLPF
MMAR_3796|M.marinum_M               EIAVSEDL--DVAGMEIHPALLDAALHAWVLAS-DAEGAASRDEGVQLPF
Rv2048c|M.tuberculosis_H37Rv        EVALPADAGVSVTGFGVHPVLLDAALHAVVLS---AESAERGQGSVLVPF
TH_2454|M.thermoresistible__bu      EEAIRARCPQPLPAGHVVDTLAGLGVAAMGFG------------------
                                    :               :  .: .                           

Mflv_0405|M.gilvum_PYR-GCK          RYGQVSLQEKMPRRFYCRATWHEAPLDSETQVFDLEYLDRDGRHLGGVRE
MAB_0939|M.abscessus_ATCC_1997      RYGQVTLKEKMPRRFYCRARWHESPLDSETQVFDLDYLDRDGRHLGGIRE
MSMEG_0408|M.smegmatis_MC2_155      RYGQVTLAEKMPRRFYCRARWHRSALDSETQVFELEFVDLGGRALGGIRE
Mvan_1003|M.vanbaalenii_PYR-1       RYGRVEVRERMPRRFYCRARWQTGGIDSETQVFDLDFLDHDGRNLGGIRE
Mb2971c|M.bovis_AF2122/97           CWRGVSLHAGGAGRVRARFAS------AGADAISVDVCDATGLPVLTVRS
MLBr_00135|M.leprae_Br4923          CWRGVSLHAGGAGRVRARFTS------AGADAIAVDIADSAGLPVLTVRS
MUL_2005|M.ulcerans_Agy99           CWRGVSLHAGGAGRVRARLTM------SGPDSISVEIADAAGLPVLTVGA
MAV_3108|M.avium_104                SWQGVSLHAAGASRVRVRLAP------AGAGAVSVELADASGVPVLSVRE
MMAR_3796|M.marinum_M               MWQQVSLHGVGATRLRVHLAR------TQSNVVDVQLCDTSGMLVFTG-S
Rv2048c|M.tuberculosis_H37Rv        SWQGVSLHAAGASAVRARIAP------VGPSAVSIELADGLGLPVLSVAS
TH_2454|M.thermoresistible__bu      -WEVLELHRGEGELFARVAAEP----DKSAPATWAGLIDAATSTASTIFD
                                     :  : :       .              .        *           

Mflv_0405|M.gilvum_PYR-GCK          FTVKRAPREALLRGLGGDATRLLYTLGWHEVPVP----ESGDGAAPQGTW
MAB_0939|M.abscessus_ATCC_1997      FTVKRAPREALLRGLGGDATRLLYTLGWHEVAVPPVAGEGEESAASIGTW
MSMEG_0408|M.smegmatis_MC2_155      FTVKRAPREALLRGLGGDATRLLYTLGWHEVPPP------PSADDAVGTW
Mvan_1003|M.vanbaalenii_PYR-1       FTVKRAPREALLRGLGADATRLIYRVGWRETSPP---VRDDGALGPSSTW
Mb2971c|M.bovis_AF2122/97           LVTRPITAEQLRAAVTAAGG-ASDQGPLEVVWSP-----ISVVSGGANGS
MLBr_00135|M.leprae_Br4923          LVTRAMTAEQLRTAVTAAGG-ALEQGPMDLVWSP-----IPLSSDGHGG-
MUL_2005|M.ulcerans_Agy99           LVTRAMSAAQLRAAVAEAGGGAPDQGPLDVIWSP-----IPLSGSGTNGS
MAV_3108|M.avium_104                LVTRAVSAEQLAAAVAVRSG---SGELLDVAWSV-----IEPRNSLPDNP
MMAR_3796|M.marinum_M               LLTRPVSPEKIHAALSAAGTQD-DSGLMELTWAP-----ITLPEGRAGRI
Rv2048c|M.tuberculosis_H37Rv        MLARPVTDQQLRAAVSSSGPD----RLFEVTWSP-----QPS--------
TH_2454|M.thermoresistible__bu      GPPRLRMPARIERVHVRDKPPAIALLHVRRRPEG----------------
                                       :      :                                       

Mflv_0405|M.gilvum_PYR-GCK          LIGGFDELAVSVPGCIPADR----------------TNPESLRQLLTDAH
MAB_0939|M.abscessus_ATCC_1997      LIAGFDELAAKVPGCIPLNRE---------------TDPELLGEVLVAAK
MSMEG_0408|M.smegmatis_MC2_155      LIAGFDELAAKVPGCVPIDRN---------------TDLQVLGEVLSQAH
Mvan_1003|M.vanbaalenii_PYR-1       LVAGLDALADDVPGSIRIGFDRIWDPDRDGRVVLDPADDEHWRRLFALAD
Mb2971c|M.bovis_AF2122/97           APPAPVSWADFCAGSDG---------------------------------
MLBr_00135|M.leprae_Br4923          GLPSVVSWADYCAGRGN---------------------------------
MUL_2005|M.ulcerans_Agy99           AQPAVVSWADFCAGGDGGAAG-----------------------------
MAV_3108|M.avium_104                ISEGVTVWEPAAVDGAG---------------------------------
MMAR_3796|M.marinum_M               VAWRDQSTVDPVSEADPAGGV-----------------------------
Rv2048c|M.tuberculosis_H37Rv        ------AAVEPLPVCAWGTTE-----------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          GRGLPFSGVVWRAARSDGDES--DAEVAARLEAEIAELLGAVHTVQ---G
MAB_0939|M.abscessus_ATCC_1997      ERGVPFSGVVWRAAGPGATES--TTESAARLEGEIAHLLSAVHTVQNSAQ
MSMEG_0408|M.smegmatis_MC2_155      ARGAGFSGVVWRCATPGRKESGSASAESARLEAEITNLLSAVHAAQ---G
Mvan_1003|M.vanbaalenii_PYR-1       ERRAPVAGVVLGVTGRARPEE-PSADFAARLEAQIRDVLGAVHSLS---A
Mb2971c|M.bovis_AF2122/97           -----DASVVVWELESAGGQASS---VVGSVYAATHTALEVLQSWLG---
MLBr_00135|M.leprae_Br4923          -----DTGVVVWEFGSASAGAQAPVDSVAAVYSATHAALQVLQFWFG---
MUL_2005|M.ulcerans_Agy99           -----DAGVVVWEPNPAG------EDVVGPVYAATHAALEVLQSWFD---
MAV_3108|M.avium_104                ---------------------------PAAVHAATHQALGVLQSRLA---
MMAR_3796|M.marinum_M               -----QADVVVWEVPATHR------DVVASVHEVTHQLLAVLQSWLT---
Rv2048c|M.tuberculosis_H37Rv        -----DSAAVVFESVPLAG------DVVAGVYAATSSVLDVLQSWLT---
TH_2454|M.thermoresistible__bu      -------------------------TVTDVTIAEESGAVSVTLTGMG---
                                                                          : .         

Mflv_0405|M.gilvum_PYR-GCK          GEVKLPGGLWIVTERAVATESGEPVDPVQAALWGFGRTAINEEPALRCRL
MAB_0939|M.abscessus_ATCC_1997      NGVKLPGGLWIVTERAVATESGEPVDPVQAALWGFGRTTINEEPALRAKL
MSMEG_0408|M.smegmatis_MC2_155      PSVKLPGGLWIVTEHGVACESGEPVDPVQAALWGFGRTTINEEPALHCRL
Mvan_1003|M.vanbaalenii_PYR-1       LGAKPAAGLWIVTERAVAAEAGEPVDPVQSALWGLGRTLIAEEPGLRCLL
Mb2971c|M.bovis_AF2122/97           --ADRAATLVVLTHGGVGLAGEDISDLAAAAVWGMARSAQAENP-GRIVL
MLBr_00135|M.leprae_Br4923          --QDRAGTLVVLTRGAVGLVGEGISDLAAAAVWGMVRSAQSEHS-GKIVL
MUL_2005|M.ulcerans_Agy99           --GDRAGTLVVLTHGAVAMPGENVSDLAGAAVWGIVRSAQAENP-GRIVL
MAV_3108|M.avium_104                --GEAGGVLVVSTRGAVGLPGEDVADLAGAAVWGLVRSAQAEHP-GRVVL
MMAR_3796|M.marinum_M               --VDRAGVLVVLTRGAVGLVGERVSDLAGAAVWGMVRSAQNEHP-GQVLL
Rv2048c|M.tuberculosis_H37Rv        --RDGAGVLVVMTRGAVALPGEDVTDLAGAAVWGLVRSAQTEHP-GRIVL
TH_2454|M.thermoresistible__bu      --------FEELENPGGGGSSGDLTGMLHHLRWHPVDWPDTDPP-AAVVL
                                            :    . . .  .    .      *        : .     *

Mflv_0405|M.gilvum_PYR-GCK          VDCDGSPQAVQALAALLSTP-VDEPELAVRQGKLLASRLLPWSRSGHLTV
MAB_0939|M.abscessus_ATCC_1997      VDGDGSPEAVQALARLLVTP-VDEPEIAVRQGKLLASRLLPWSRTGHLTV
MSMEG_0408|M.smegmatis_MC2_155      VDCDGSSEAVDLLAALLAAPGIQEPEIAVRQGKLLASRLLPWARSGHLTL
Mvan_1003|M.vanbaalenii_PYR-1       VDLDGSEDAGPALARLLGAP-GDEPELALRQGRLLVPRLLPWSRSGQLAI
Mb2971c|M.bovis_AF2122/97           IDTDAAVDASVLAG-------VGEPQLLVRGGTVHAPRLSPAP--ALLAL
MLBr_00135|M.leprae_Br4923          IDTDSAVDVAVLAD-------LGESQLLVRCNTVHAARLSPAP--QLLAL
MUL_2005|M.ulcerans_Agy99           VDADAAVEAAELVA-------VGEPQLVVRSGAAHAARLAPAA--PLLAV
MAV_3108|M.avium_104                VDTDGSLDLATVIG-------CGEPQLVVRDGVAYRARLRPAGRRALLEL
MMAR_3796|M.marinum_M               VDLDA-----------------------------------AASIVDGQIV
Rv2048c|M.tuberculosis_H37Rv        VDSDAPLDDSALAAVV----TTGEPQVLWRRGEVYTARVHGSRAVGGLLV
TH_2454|M.thermoresistible__bu      VGGDAR--------------------------------------------
                                    :. *.                                             

Mflv_0405|M.gilvum_PYR-GCK          PRGGD-YVLAPTERGAIDNLRLTDSEVPPP--AEGYVQVRVEAAGLNFRD
MAB_0939|M.abscessus_ATCC_1997      PRGSD-YVLAPTERGAIDNLRITEKEVPAP--DEGYVQVRVEAAGLNFRD
MSMEG_0408|M.smegmatis_MC2_155      PRGGD-FVLAPTERGAIDNLRLTETDVPEP--DEGYVQVRVEAAGLNFRD
Mvan_1003|M.vanbaalenii_PYR-1       PRGTD-YVLAPTERGVLDNLRVSETEVTAP--PEGHVQVRVEAAGLNFRD
Mb2971c|M.bovis_AF2122/97           PAAESAWRLAAGGGGTLEDLVIQPCPEVQAPLQAGQVRVAVAAVGVNFRD
MLBr_00135|M.leprae_Br4923          PVGESMWRLAADGGGTLEDLVIQPCPEVQAPLQAGHMRVAVAAVGVNFRD
MUL_2005|M.ulcerans_Agy99           PADESAWRLAAGGGGTLEDLVIEPCPEVQAPLAAGQVRVAVRAVGVNFRD
MAV_3108|M.avium_104                PGPPAVWRLAAGDAGTLEDLAVQEHP--AAELAPGQVRVRVAAAGVNFRD
MMAR_3796|M.marinum_M               TDSD----------------------------GSDMRGLDLAALTK----
Rv2048c|M.tuberculosis_H37Rv        PPSDRPWRLAMSTAGTFENLRLELIPDADAPLGPGQVRVAVSAIAANFRD
TH_2454|M.thermoresistible__bu      --------------------------------TRAFVTRDLDEARVAHR-
                                                                            :         

Mflv_0405|M.gilvum_PYR-GCK          VLNVLGLYPGDPGPIGGDFAGTVTQLGEGVTGLDVGQRVYGSMQGAFASR
MAB_0939|M.abscessus_ATCC_1997      VLNVLGLYPGDPGPIGGDFAGIVTQLGEGVTGVEVGQRVYGSMQGAFGSR
MSMEG_0408|M.smegmatis_MC2_155      VLNVLGLYPGDPGPIGGDFAGTVTQLGAGVSGLEIGQRVYGSMQGAFASR
Mvan_1003|M.vanbaalenii_PYR-1       VLNALGLYPGDPGPIGGELAGVVTAPGPDVDGFDVGQRVFGFAVGAFASR
Mb2971c|M.bovis_AF2122/97           VVAALGMYPGQAPPLGAEGAGVVLETGPEVTDLAVGDAVMGFLG-GAGPL
MLBr_00135|M.leprae_Br4923          VVAALGMYPGQAPPLGAEGAGVVIEIGPEVTGVAVGDAVMGFLG-GAGPL
MUL_2005|M.ulcerans_Agy99           VVAALGMYPGAAPPLGAEGAGVVLEVGPQVSGVAVGDSVMGFLG-GAGPL
MAV_3108|M.avium_104                VLVALGMYPGAAQ-LGAEGAGVVTEVGAGVTDVAVGDAVMGIFG-LVGSE
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        VMIALGLYPDPDAVMGVEACGVVIETSLNKGSFAVGDRVMGLFPEGTGTV
TH_2454|M.thermoresistible__bu      ---------------------------------------------SYADP
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          FNVPGQFLAPIPDGVSAVEAATIPAAALTVRLS-FDWAQVKSGDKVLIHA
MAB_0939|M.abscessus_ATCC_1997      FNVPAQFLAPIPDGISGVEAATIPAAALTVRLS-FDWAQLKPGDKVLIHA
MSMEG_0408|M.smegmatis_MC2_155      FNVPAQFLAPIPDGIGAVEAATIPAAALTVRLA-FDWAQLKPGDKVLIHA
Mvan_1003|M.vanbaalenii_PYR-1       VNVPVQFLAPVPEGISAVAAATTPAAVLTAGLA-FDWAALRAGDRVLIHA
Mb2971c|M.bovis_AF2122/97           AVVDQQLVTRVPQGWSFAQAAAVPVVFLTAWYGLADLAEIKAGESVLIHA
MLBr_00135|M.leprae_Br4923          AVVHQQLITQMPQGWSLAEAAAVPVVFLTALFGLADLAGIRAGESVLIHA
MUL_2005|M.ulcerans_Agy99           SVVDQQLITRMPQGWSFAQAAAVPVVFLTALFGLQDLAKIQPGESVLIHA
MAV_3108|M.avium_104                AAVDRRLVTRVPPGWSMAQAAGIPVVFLTAYYGLSVLAGLRAGQRVLVHA
MMAR_3796|M.marinum_M               -SGETQLVVRS---------------------------------------
Rv2048c|M.tuberculosis_H37Rv        ASTDQRLLVKVPAGWSHTAAATTSVVFATAHYALVDLAAARSGQRVLIHA
TH_2454|M.thermoresistible__bu      AALPPDLTAGTVVLVLPRTAARPAASAQLVLHTLQRLSATNSGARLWVLT
                                          : .                                         

Mflv_0405|M.gilvum_PYR-GCK          ASGGVGLAAVQMAQQCGAEVYATASTFKRATLRKLG--VKHVYDSRTTDF
MAB_0939|M.abscessus_ATCC_1997      ASGGVGLAAIQMAQQFGAEVFATASTFKRATLRKLG--VKYVYDSRTTDF
MSMEG_0408|M.smegmatis_MC2_155      ASGGVGLAAIQMAQQSGAEVFATASTFKRSTLRRLG--VKYVYDSRTTDF
Mvan_1003|M.vanbaalenii_PYR-1       ASGGVGLAAVQLARQRGATVFATASGYKRPMLRAMG--VDHVYDSRTTDF
Mb2971c|M.bovis_AF2122/97           GTGGVGMAAVQLARQWGVEVFVTASRGKWDTLRAMGFDDDHIGDSRTCEF
MLBr_00135|M.leprae_Br4923          GTGGVGMAAVQFARHWGVEIFVTASRGKWDTLRDMGFDDDHIGDSRTLEF
MUL_2005|M.ulcerans_Agy99           GTGGVGMAAVQLARHWGVEIFVTASRGKWDTLRAMGFDDDHIGDSRTLDF
MAV_3108|M.avium_104                ATGGVGMAAVQLARHWGAEVFATASRGKWDTLRAMGFDDAHIADSRTLDF
MMAR_3796|M.marinum_M               ---------------------------------------QQVYAARLSAM
Rv2048c|M.tuberculosis_H37Rv        GTGGVGMAAVQLARHLGLEVFATASKGKWDTLRAMGFDDDHISDSRSLEF
TH_2454|M.thermoresistible__bu      RGVHEGTDPGHGPLWGLARVAAAEHPQLWGGLLDIG----------EDRL
                                                                                     :

Mflv_0405|M.gilvum_PYR-GCK          AEQILADTDGAGVDVVLNSLTSEGFIEATLRATAQHGRFAEIAKRDIWTV
MAB_0939|M.abscessus_ATCC_1997      ADQILADTDGAGVDVVLNSLTSEGFIEATLRATAKNGRFAEIAKRDIWTT
MSMEG_0408|M.smegmatis_MC2_155      ADQILADTNGAGVDVVLNSLTSAGFVEATLKATAQGGRFAEIAKRDIWSH
Mvan_1003|M.vanbaalenii_PYR-1       ADQILADTDGAGVDVVLNSLTNDGFVAATVRATARNGRFAEIAKRDIWSP
Mb2971c|M.bovis_AF2122/97           EEKFLAVTEGRGVDVVLDSLAGE-FVDASLRLLVRGGRFLEMGKTDIRDA
MLBr_00135|M.leprae_Br4923          EEKFLAVTDGRGVDVVLDSLAGD-FVDASLRLLVRGGRFLEMGKTDIRDA
MUL_2005|M.ulcerans_Agy99           EEKFLAVTDGRGVDVVLDSLAGD-FVDASLRLLVRGGRFLEMGKTDIRDA
MAV_3108|M.avium_104                EQKFGAAPG--GMDVVLNSLAGE-FNDASLRLLGPGGRFIEMGKTDLRDP
MMAR_3796|M.marinum_M               APTLEVADGGG---------------------VKP---------SSMLDP
Rv2048c|M.tuberculosis_H37Rv        EDKFRAATGGRGFDVVLDSLAGE-FVDASLRLVAPGGVFLEMGKTDIRDP
TH_2454|M.thermoresistible__bu      PVRALTALTGHGVVVVRDGVAHT------ARLAPAGPGARDSAGEGLRCS
                                         .                                       .:   

Mflv_0405|M.gilvum_PYR-GCK          EQMAAARPDLAYEIVALDTVMFTEPDRIRDLLTEVSAGLRDGAWTPLPAE
MAB_0939|M.abscessus_ATCC_1997      EQMAQSRPDIAYEIVALDTVMFQEPDRIRVLLTEVSEGLAKGEWTPLPAE
MSMEG_0408|M.smegmatis_MC2_155      EQMAEARPDIAYEIVALDTVMFTEPDRIRDLLTEVSDGMARGEWTPLPAE
Mvan_1003|M.vanbaalenii_PYR-1       EQMAAARPDIDYEVLALDAVMQQDPDRIQLLLADLADSLARGETAPLPFE
Mb2971c|M.bovis_AF2122/97           QEIAANYPGVQYRAFDLSEAG---PARMQEMLAEVRELFDTRELHRLPVT
MLBr_00135|M.leprae_Br4923          QEIAANYPGVQYRAFDLSEAG---PVRMQEMLCEVRELFDTQVLHRLPVT
MUL_2005|M.ulcerans_Agy99           DKIAANYPGVWYRAFDLSEAG---PVRMQEMLAEVRELFDTAVLHRLPVT
MAV_3108|M.avium_104                DVVARAHPGVRYRAFDLMEAG---PDRIAAMLAEVMELFAAGALTPLPVK
MMAR_3796|M.marinum_M               --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        GVIAQQYPGVRYRAFDLFEPG---PDRIAQILAELATLFGDGVLRPLPVT
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          VYPLTEARAAFRRMQQARHIGKIVVQIPNPLQP-QPDRSYLITGGLGAIG
MAB_0939|M.abscessus_ATCC_1997      IYPLTEARTAFRRMQQARHIGKIVCQMPNPLAP-RPDRTYLITGGLGAIG
MSMEG_0408|M.smegmatis_MC2_155      IYPITEARSAFRRMQQARHIGKIVLQVPKPLQP-QQDRSYLITGGLGAIG
Mvan_1003|M.vanbaalenii_PYR-1       AYPLAEATTAFRRMQQARHTGKIILQMPKPLQP-HGDRSYLITGGLGALG
Mb2971c|M.bovis_AF2122/97           TWDVRCAPAAFRFMSQARHIGKVVLTMPSALADRLADGTVVITGATGAVG
MLBr_00135|M.leprae_Br4923          SWDVRCAPAAFRFMSQARHIGKVVLTMPSALADGLAEGTVLITGASGAIG
MUL_2005|M.ulcerans_Agy99           TWDVRCAPAAFRFMSQARHIGKVVLTMPSALADGLADATVLITGATGAVG
MAV_3108|M.avium_104                AFDARCAADAYRFVSAARHIGKVVLTMPDGPAG-LSGGTALITGATGMAG
MMAR_3796|M.marinum_M               ------------------------------------SGTVLITGGTGMAG
Rv2048c|M.tuberculosis_H37Rv        TFDVRCAPAALRYLSQARHTGKVVMLMP----GSWAAGTVLITGGTGMAG
TH_2454|M.thermoresistible__bu      -----------------------------------PGGTYLITGGTGALG
                                                                          : :***. *  *

Mflv_0405|M.gilvum_PYR-GCK          -LHTAGYLAQLGAGDIVLTSRRAPDA---------AAQQAIADIADRTKA
MAB_0939|M.abscessus_ATCC_1997      -LHTAAYLAQLGAGDIVLTSRRAPDT---------DAQRVIGEITERSKT
MSMEG_0408|M.smegmatis_MC2_155      -LHTAAYLAQLGAGDIVLTSRRDPDE---------SAQRAIDEITERHKC
Mvan_1003|M.vanbaalenii_PYR-1       -LHAAAYLAQLGAGDIVLTGRRMPDA---------ATERAISEIAERYHC
Mb2971c|M.bovis_AF2122/97           GVLARHLVGAYGVRHLVLASRRGDRA---------EGAAELAADLTEAGA
MLBr_00135|M.leprae_Br4923          GVLARHMVSAYGVRHLVLASRRGDRA---------EGAVELAAELVGAGA
MUL_2005|M.ulcerans_Agy99           AVLARHMLDGYGVRHLVLASRRGDRA---------EGAAELAAELSEAGA
MAV_3108|M.avium_104                AALARHLVARHRVPHLMLVGRRGEAA---------PGMAELAAELRGAGA
MMAR_3796|M.marinum_M               GWLARHVVDHYGVRHVLLASRSGDRA---------GGSAEIAAELAARGV
Rv2048c|M.tuberculosis_H37Rv        SAVARHVVARHGVRNLVLVSRRGPDA---------PGAAELVAELAAAGA
TH_2454|M.thermoresistible__bu      -LRLAHRLADLGARRLVLVSRSGMPARDSWGRAGDSDTVAAITALEERGV
                                           :    .  ::*..*                             

Mflv_0405|M.gilvum_PYR-GCK          RLHVFTADVGVEADVAALLERIRAELPPLAGVAHLAGVLDDALLSQQSVE
MAB_0939|M.abscessus_ATCC_1997      RIHVFTADVGAESEVAGLLERIRAELPPLAGVAHLAGVLDDALLGQQSVE
MSMEG_0408|M.smegmatis_MC2_155      RIHTYAADVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPE
Mvan_1003|M.vanbaalenii_PYR-1       RIHTFAADVGDESAVRDLLERIRTELPPLAGVAHLAGVLDDALLPQQSPE
Mb2971c|M.bovis_AF2122/97           KGQVVACDVADRAAVAGLFAQLSREYPPVRGVIHAAGVLDDAVITSLTPD
MLBr_00135|M.leprae_Br4923          KIQVVACDVADNDAVRGLFAQLSREFPPVRGVIHAAGVLDDGAITSLTPD
MUL_2005|M.ulcerans_Agy99           NVQVVACDVADRDAVEAMLARLSGEYPPVRGVIHAAGVLDDAVISSLTPE
MAV_3108|M.avium_104                SVSVLSCDVGDRDAVAAMLAQVPARYP-LRSVFHAAGVLDDAVIASLTPA
MMAR_3796|M.marinum_M               QVEVVACDVADRDAVTALLARLPQQYP-LTGVIHAAGVLDDAVITSLTPD
Rv2048c|M.tuberculosis_H37Rv        QVQVVACDAADRAALAKVIADIPVQHP-LSGVIHTAGALDDAVVMSLTPD
TH_2454|M.thermoresistible__bu      SVRVAALDIG-APGAAARLREVLADLPDVRGVIHAAGVEAGALLTNTTAE
                                       . : * .        :  :    * : .: * **.  .. :   .  

Mflv_0405|M.gilvum_PYR-GCK          RFRTALAPKAFGAVHLDRLTRVDDLDFFLVSSSVSSLFGSPGQSNYATAN
MAB_0939|M.abscessus_ATCC_1997      RFRTTLAPKAFGAEYLDRLTKGDDLDFFIVSSSVSSLFGSPGQSNYATAN
MSMEG_0408|M.smegmatis_MC2_155      RFRTTLAPKAYGASHLDRLTRDDDLDFFIVSSSVSSLFGSPGQANYATAN
Mvan_1003|M.vanbaalenii_PYR-1       RFRTTLAPKAFGAWHLHRLTRDTELEFFIVYSSGSSVLGSPGQANYATAN
Mb2971c|M.bovis_AF2122/97           RIDTVLRAKVDAAWNLHQATSDLDLSMFVLCSSIAATVGSPGQGNYSAAN
MLBr_00135|M.leprae_Br4923          RVDTVLRAKVDAAWNLHEATRDLDLLMFVLCSSIAATVGSPGQGNYSAAN
MUL_2005|M.ulcerans_Agy99           RIDTVLRAKVDAAWNLHEATLDLDLSMFVLCSSIAATVGSPGQGNYSAAN
MAV_3108|M.avium_104                RIDTVLRAKVDGAWNLHELTKDLDLSAFVVFSSMAGIVGAPGQGNYAAAN
MMAR_3796|M.marinum_M               RVDTVLRAKVDAAWNLHELTRDLGVSAFVLFSSIAGTVGAPGQGNYAAAN
Rv2048c|M.tuberculosis_H37Rv        RVDVVLRSKVDAAWHLHELTRDLDVSAFVMFSSMAGLVGSSGQANYAAAN
TH_2454|M.thermoresistible__bu      DIEATMRPKVDGVLALHEVFPPGRLDWLVLFSSCGYLGGFPGQGAYACGN
                                     . ..: .*. ..  *..      :  ::: ** .   * .**. *: .*

Mflv_0405|M.gilvum_PYR-GCK          AFLDGLVAQRRAQGLPATGVNFGPWARGGMASSEAAAAN---ISAQGLIP
MAB_0939|M.abscessus_ATCC_1997      ALLDGLIAQRRAQGLPATGINFGPWGQGGMASSEAATAN---ISAQGLIP
MSMEG_0408|M.smegmatis_MC2_155      AMLDGLVAKRRAQGLVATGINFGPWGQGGMASSEAATAN---ITAQGLIP
Mvan_1003|M.vanbaalenii_PYR-1       AVLDGLVAHRKARGLPATGVNWGPWAQGGMATSDAARAN---LGAQGLIP
Mb2971c|M.bovis_AF2122/97           AFLDGLAAHRQAAGLAGISLAWGLWEQPGGMTAHLSSRDLARMSRSGLAP
MLBr_00135|M.leprae_Br4923          AFLDGLAAYRQAAGLAGTSLAWGLWEQPGGMNAHLSSRDLARISRSGLAP
MUL_2005|M.ulcerans_Agy99           SFLDGLAAHRQAAGLAGISVAWGLWEQSGGMAAHLSSRDLARMSRSGLAP
MAV_3108|M.avium_104                SFLDALAIHRHAHGLPALSVAWGMWEEPSAMTAHLEERDKARMSRAGLSA
MMAR_3796|M.marinum_M               AFLDALAFQRRADGLTATSLAWGLWERSSTMTGHLSSRDMTRMNRTGMVA
Rv2048c|M.tuberculosis_H37Rv        SFLDALAAHRRAHGLPAISLGWGLWDQASAMTGGLATVDFKRFARDGIVA
TH_2454|M.thermoresistible__bu      AYLDAFARYRRASGDATTSVAWTAWRGLG--MGSASDFVAAQLDALGMGT
                                    : **.:   *:* *    .: :  *   .   .         :   *: .

Mflv_0405|M.gilvum_PYR-GCK          LEPSAALTAMAEVVANGTAQATVLKAN-WQRAAKVLGSSRPPILDLVLPS
MAB_0939|M.abscessus_ATCC_1997      LDPSAALAALAEVVANGTGQATILKAN-WQRAAKVLGSSRPPILDLVLPS
MSMEG_0408|M.smegmatis_MC2_155      LDPSAALHALAEVIANGSGQATVLKAN-WQRAAKVLGSARPPILDLVLPS
Mvan_1003|M.vanbaalenii_PYR-1       LEPTAALNALGEIVAHGIASAVVLKAN-WQRAAKLLGATRPPILDHVLPS
Mb2971c|M.bovis_AF2122/97           MSPAEAVELFDAALAIDHPLAVATLLDRAALDARAQAGALPALFSGLARR
MLBr_00135|M.leprae_Br4923          MNPAQALELFDAALVIDHPFMVTALLDRAALDAQAQAGALPPLFSRLVRR
MUL_2005|M.ulcerans_Agy99           MNPEQAVGLLDAVLAINHPLMVATLLDRPALEARAQAGGLPPLFAGVVRR
MAV_3108|M.avium_104                LSTRQALDLLDDALLGEQPLVVGTRLDRAALAQHRAA--LPPLLSELAGR
MMAR_3796|M.marinum_M               LTAEQAVEMFDAALVAGHPAVVAGRFDRRMLHNPSFNAGLPPLFNELIGS
Rv2048c|M.tuberculosis_H37Rv        MSSADALQLFDTAMIVDEPFMLPAHIDFAALKVKFDGGTLPPMFVDLINA
TH_2454|M.thermoresistible__bu      VDVDDAMRALDAAIRDGDPNVVVLPLSPAAAAVPMFADVAPADPDADAP-
                                    :    *:  :   :            .             *.        

Mflv_0405|M.gilvum_PYR-GCK          AVG--------EITGDSELLKQLQEIPVPQRAGFVTEFLQKEVQNFLRLA
MAB_0939|M.abscessus_ATCC_1997      AVG--------EVTGDSELLKQLMEIPVPQRAGFVTEFLQREVQNFLRLA
MSMEG_0408|M.smegmatis_MC2_155      AAG--------EATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLA
Mvan_1003|M.vanbaalenii_PYR-1       AVA--------AGPGDSALLKQLQDVPEAQRGSFVTEHLQRELQQILGLA
Mb2971c|M.bovis_AF2122/97           PRRRQIDDTGDATSSKSALAQRLHGLAADEQLELLVGLVCLQAAAVLGRP
MLBr_00135|M.leprae_Br4923          SRRRQIEDPGDATQSKLALVQRLQGLAANRQLELLVGVVCLQAAAVLGRP
MUL_2005|M.ulcerans_Agy99           PRRRQIEDTGDAAQSKSALAERLNGLSAGERQDALVGLVCLQAAAVLGRP
MAV_3108|M.avium_104                PARRMLEHT--DMVSLTGLRARLAGMNPEQRQAELVELVCGNAAAVLG-H
MMAR_3796|M.marinum_M               PRRRTIEAGSLASQS--ALTQRLHGLTPEQQREMLTELVCTQIAIALGHN
Rv2048c|M.tuberculosis_H37Rv        PTRRQVDDSLAAAKSKSALLQRLEGLPEDEQHAVLLDLVRSHIATVLGSA
TH_2454|M.thermoresistible__bu      ---------GGEVPDGLSDGFPADGFPDDGDLAEWVHRRVIAAVAGELGL
                                                  .          .                        

Mflv_0405|M.gilvum_PYR-GCK          QPPAATS--RFLDLGTDSLMAIELRNRLHSQFGGAFTINATAVFDYPTIG
MAB_0939|M.abscessus_ATCC_1997      QPPAATS--RFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIG
MSMEG_0408|M.smegmatis_MC2_155      SPPAASS--RFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIG
Mvan_1003|M.vanbaalenii_PYR-1       QPPAATG--RFLELGMDSLMAVELRNRLVGQFGSGFTITATAVFDYPTIG
Mb2971c|M.bovis_AF2122/97           SAEDVDPDTEFGDLGFDSLTAVELRNRLKTATG--LTLPPTVIFDHPTPT
MLBr_00135|M.leprae_Br4923          SPEDIDPNTKFQDLGFDSLTAVELRNRLKSATG--LTLPPTVIFDHPTPT
MUL_2005|M.ulcerans_Agy99           SPEDIDPEAGFQDLGFDSLTAVELRNRFKSATG--LTLPPTVIFDHPTPT
MAV_3108|M.avium_104                STADVDPGDAFSDLGFDSLTAVELRNRLKIATG--LTLSPTVIFDHPTPA
MMAR_3796|M.marinum_M               NSSEINPDQAFQGLGFDSLTAVELRNRLKAATG--LSLTPTLVFDYPTPR
Rv2048c|M.tuberculosis_H37Rv        SPEAIDPDRAFQELGFDSLTAVEMRNRLKSATG--LALSPTLIFDYPNSA
TH_2454|M.thermoresistible__bu      AETDVDPRLPLVEIGVDSIMTVALRRQLERQTG--LTLPPTLLWEHPTAG
                                              :  :* **: :: :*.::    *  ::: .* ::::*.  

Mflv_0405|M.gilvum_PYR-GCK          GLAEYLVAQLPDAETPQAAP-------QSESEPGPDVTE-----------
MAB_0939|M.abscessus_ATCC_1997      GLAEYLVGQLPDADAESAEAPPAVESAEAESGAGPAAASDAVSELKE---
MSMEG_0408|M.smegmatis_MC2_155      GLAEYLVGQLPDAEAPETA-------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       ALAEYLAAQTPESTEEGTEMKTADPDGQPATVGHADVVLQTS--------
Mb2971c|M.bovis_AF2122/97           AVAEYVAQQMSGSRPTESGDPTSQVVEPAAAEVSVHA-------------
MLBr_00135|M.leprae_Br4923          AVAEYVAQQMLKSRPAESGDETSQAVEPKVEEVSVHA-------------
MUL_2005|M.ulcerans_Agy99           AIAEYVGRQIPDSQATQAEEE--KLPESDGEMVSVTA-------------
MAV_3108|M.avium_104                ALAEHLGGQLTSAGPTPAAPAETAAPPDRSSRIDEVVSELQTLLTQPGLS
MMAR_3796|M.marinum_M               DVASYLEYQLGGSEPID-GGNDDYVRQVQELVMSIPAKRLA---------
Rv2048c|M.tuberculosis_H37Rv        ALAGYMRRELLGSSPQDTSAVAAGEAELQRIVASIPVKRLR---------
TH_2454|M.thermoresistible__bu      AVSDRIVEMLRARG------------------------------------
                                     ::  :                                            

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb2971c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MUL_2005|M.ulcerans_Agy99           --------------------------------------------------
MAV_3108|M.avium_104                PGDRAQLVTRLQSLLSTPPQPSGHPEFPEDAFDDDIATATDSQLFAILDD
MMAR_3796|M.marinum_M               ---QANVVDLLQKLKTDISDQLDE----RESASNLADMSLDDLVDVALTK
Rv2048c|M.tuberculosis_H37Rv        ---QAGVLDLLLALANETETSGQDPALAPTAEQEIADMDLDDLVNAAFRN
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ------
MAB_0939|M.abscessus_ATCC_1997      ------
MSMEG_0408|M.smegmatis_MC2_155      ------
Mvan_1003|M.vanbaalenii_PYR-1       ------
Mb2971c|M.bovis_AF2122/97           ------
MLBr_00135|M.leprae_Br4923          ------
MUL_2005|M.ulcerans_Agy99           ------
MAV_3108|M.avium_104                EAGP--
MMAR_3796|M.marinum_M               FAAQQG
Rv2048c|M.tuberculosis_H37Rv        DDE---
TH_2454|M.thermoresistible__bu      ------