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MQSGDSQRWNNPWPGKSWPGMSSLAEVGTMAGRPQLRIGTHGQIKRIYTGGGVWLARCRYRDTDGVTRIV QRLGPADEYDQHGKLAADALIAALAQRRHSANHGEIGPDTKVTDLVEQHLSRLAEDGRSPVTMSTYRFTT KNLKKFIGGLRVSEATPARMDATLRSMRSAHGATMARQSKSILRGALQLAVMASVLGANPVRDVQPLRSQ SQPKGAVALTADQLRELLARLQTSDFCKEHDLIDPITLLIATGLRRSELLGLRWVDFDEKASMLAITGKV IRVPGEGLLRVDETKSAAGRRTIPLPKFAVDVLGKRRQLPYLGEQVVIFPSTAGTLRDPNNFGKEWRTAR EELGVAEVTTHSFRKTVATLIDDEGLSARIGADHLGHSHVSMTQDRYMTRGRIHTQVAHLLDRAVRINDE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3607 | - | - | 100% (420) | phage integrase |
| M. marinum M | MMAR_3584 | - | 8e-33 | 49.33% (150) | phage-related integrase |
| M. marinum M | MMAR_3585 | - | 3e-25 | 77.61% (67) | phage-related integrase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1727 | xerD | 3e-06 | 25.93% (297) | site-specific tyrosine recombinase XerD |
| M. gilvum PYR-GCK | Mflv_2786 | - | 4e-12 | 24.87% (374) | phage integrase family protein |
| M. tuberculosis H37Rv | Rv2659c | - | 4e-07 | 24.90% (245) | phiRv2 prophage integrase |
| M. leprae Br4923 | MLBr_01365 | xerD | 2e-05 | 24.15% (265) | site-specific tyrosine recombinase XerD |
| M. abscessus ATCC 19977 | MAB_1816c | - | 1e-147 | 65.03% (386) | Phage integrase |
| M. avium 104 | MAV_0253 | - | 2e-13 | 29.15% (223) | site-specific recombinase, phage integrase family protein |
| M. smegmatis MC2 155 | MSMEG_5599 | - | 6e-12 | 74.42% (43) | hypothetical protein MSMEG_5599 |
| M. thermoresistible (build 8) | TH_1542 | xerD | 2e-07 | 26.42% (318) | tyrosine recombinase XerD |
| M. ulcerans Agy99 | MUL_3581 | - | 2e-30 | 64.21% (95) | phage-related integrase |
| M. vanbaalenii PYR-1 | Mvan_3747 | - | 4e-12 | 25.27% (376) | phage integrase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_1816c|M.abscessus_ATCC_199 ---------------------------------MAGRPPLRIGQHGKISR
MSMEG_5599|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3607|M.marinum_M ----MQSGDSQRWNNPWPGKSWPGMSSLAEVGTMAGRPQLRIGTHGQIKR
MUL_3581|M.ulcerans_Agy99 --------------------------------------------------
Mb1727|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01365|M.leprae_Br4923 --------------------------------------------------
TH_1542|M.thermoresistible__bu --------------------------------------------------
Mflv_2786|M.gilvum_PYR-GCK MQATTVQTPAGAWMTTTDKPPPKRTRRTEPITRRNAKNGAVSYTFQVDVG
Mvan_3747|M.vanbaalenii_PYR-1 MQATTVQTPAGAWMTTTDKPPPKRTRRTEPIMRRNAKNGAVSYTFQVDVG
MAV_0253|M.avium_104 ------------------------MAKIPDYVKALDLDSGRRYEVRPEV-
Rv2659c|M.tuberculosis_H37Rv ---------------------------------MTQTGKRQRRKFGRIRQ
MAB_1816c|M.abscessus_ATCC_199 QYVGGGVWVARCRYRDSDGVTRIVERRGPVDDFDKHGKLAEDALIEALSD
MSMEG_5599|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3607|M.marinum_M IYTGGGVWLARCRYRDTDGVTRIVQRLGPADEYDQHGKLAADALIAALAQ
MUL_3581|M.ulcerans_Agy99 --------------------------------------------------
Mb1727|M.bovis_AF2122/97 -----------------------------------MKTLALQ--LQGYLD
MLBr_01365|M.leprae_Br4923 -----------------------------------MTTAALQTQLQGYLD
TH_1542|M.thermoresistible__bu ---------------------VTTSEQVPRSDEPPHPHRVLDDQIQGYLD
Mflv_2786|M.gilvum_PYR-GCK THADGTRDRQRFTFSTFAEARREYRKISTEVAAGTFVKRDLTTVAEYLAR
Mvan_3747|M.vanbaalenii_PYR-1 THADGTRDRQRFTFSTFAEARREYRKISTEVAAGTFVKRDLTTVAEYLGR
MAV_0253|M.avium_104 TGPDGKRKQQRKRFKTLKEATDFYTRIAGDRSRGVHVAPSELTVEAAVDA
Rv2659c|M.tuberculosis_H37Rv FNSGRWQASYTGPDGRVYIAPKTFNAKIDAEAWLTDRRREIDRQLWSPAS
MAB_1816c|M.abscessus_ATCC_199 RRLPADTDTIGYDTLVMALVDQHIGRLSDDGRSPATVATYKFASDKLRNF
MSMEG_5599|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3607|M.marinum_M RRHSANHGEIGPDTKVTDLVEQHLSRLAEDGRSPVTMSTYRFTTKNLKKF
MUL_3581|M.ulcerans_Agy99 --------------------------------------------------
Mb1727|M.bovis_AF2122/97 HLTIERGVAANTLSSYRRDLRRYSKHLEERGITDLAKVGEHDVSEFLVA-
MLBr_01365|M.leprae_Br4923 YLIIERSIAANTLSSYRRDLIRYSKHLSDRGIEDLAKVGEHDVSEFLVA-
TH_1542|M.thermoresistible__bu HLSIERGVAANTLSSYRRDLRRYAEHLLARGIDDLAKVHESDVADFLVA-
Mflv_2786|M.gilvum_PYR-GCK WLDGRRDVRVNTLAGYRHSLKPVIDNLGGLGLQQLRTSDIDALVTLRLNG
Mvan_3747|M.vanbaalenii_PYR-1 WLDGRRDVRVNTLAGYRHSLKPVIDNLGGLGLQQLRTSDIDALVTLRLNG
MAV_0253|M.avium_104 WLAAQR-VRTKAMTGYVTALRPLVDHLGGKAVQAVTKADIEKVVAALRGG
Rv2659c|M.tuberculosis_H37Rv GQEDRPGAPFGEYAEGWLKQRGIKDRTRAHYRKLLDNHILATFADTDLR-
MAB_1816c|M.abscessus_ATCC_199 LGGVR--------------------------VSEAHAARMDAALRSMRTA
MSMEG_5599|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3607|M.marinum_M IGGLR--------------------------VSEATPARMDATLRSMRSA
MUL_3581|M.ulcerans_Agy99 --------------------------------------------------
Mb1727|M.bovis_AF2122/97 -------------------------------LRRGDPDSGTAALSAVSAA
MLBr_01365|M.leprae_Br4923 -------------------------------LRRGDPDSGVAALSAVSAA
TH_1542|M.thermoresistible__bu -------------------------------LRRGDPDTGAAGLSAVSAA
Mflv_2786|M.gilvum_PYR-GCK TPISQRERRGRRAAEVLAYLRSRSGGAQYADVRDELGNPGVKALDRLVAS
Mvan_3747|M.vanbaalenii_PYR-1 TPISQRERRGRRAAEVLAYLRSRSGGAQYADVRDELGNPGVKALDRLVAS
MAV_0253|M.avium_104 TSKMG-----------------------TWNAPEKIKGKQVRAKWGPSGT
Rv2659c|M.tuberculosis_H37Rv ----------------------------------DITPAAVRRWYATTAV
MAB_1816c|M.abscessus_ATCC_199 HGTTMARQAKTILQG---------------------------GLQLAVMA
MSMEG_5599|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3607|M.marinum_M HGATMARQSKSILRG---------------------------ALQLAVMA
MUL_3581|M.ulcerans_Agy99 ------------------------------------------------MA
Mb1727|M.bovis_AF2122/97 RALIAVRG----------------------------------LHRFAAAE
MLBr_01365|M.leprae_Br4923 RALIAVRG----------------------------------LHRFAVAE
TH_1542|M.thermoresistible__bu RALIAVRG----------------------------------LHRFAAAE
Mflv_2786|M.gilvum_PYR-GCK GEVIRPSRGRYVAVRDSDPVQSKIPGNVSSRTVVTMLVVLSSALDDAMRE
Mvan_3747|M.vanbaalenii_PYR-1 GEVIRPSRGRYVAVRDSDPVQSKIPGNVSSRTVVTMLVVLSSALDDAMRE
MAV_0253|M.avium_104 NHFIRRSR---------------------------------AVFEDLVQQ
Rv2659c|M.tuberculosis_H37Rv GTPTMRAHSYSLLR---------------------------AIMQTALAD
MAB_1816c|M.abscessus_ATCC_199 NVIPANPVRDVQSLRSKTRPKGATALSADQLRTLLAEIRASEYCAGNDLA
MSMEG_5599|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3607|M.marinum_M SVLGANPVRDVQPLRSQSQPKGAVALTADQLRELLARLQTSDFCKEHDLI
MUL_3581|M.ulcerans_Agy99 STLGANPVRDVQPIRLKRRPTGATALSADDLHDLLVRLRADDYCQRNDLV
Mb1727|M.bovis_AF2122/97 GLAELDVARAVRPPTPSRR--LPKSLTIDEVLSLLEGAGG-------DKP
MLBr_01365|M.leprae_Br4923 GLVDLDVARAVRPPTPGRR--LPKSLTVDEVLALLESVGG-------ESR
TH_1542|M.thermoresistible__bu GVTELDVARSVKPPTPSRR--LPKSLTVDEVLALLAGAGG-------DSE
Mflv_2786|M.gilvum_PYR-GCK GLVARNVARLVKRPAVEHH--EMATWTAEQAVRFREHVRG-------DRL
Mvan_3747|M.vanbaalenii_PYR-1 GLVARNVARLVKRPAVEHH--EMATWTAEQAVRFREHVRG-------DRL
MAV_0253|M.avium_104 GVLGRNPAALVQPVPMARA--ELNTLTAAQAERLLAATRN-------DVF
Rv2659c|M.tuberculosis_H37Rv DLIDSNPCR-ISGASTARRVHKIRPATLDELETITKAMPD-------PYQ
MAB_1816c|M.abscessus_ATCC_199 DPLIILMATGLRRSELLALRWSDFDANAGTLTVTGKLVRATGAGLQRIDE
MSMEG_5599|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3607|M.marinum_M DPITLLIATGLRRSELLGLRWVDFDEKASMLAITGKVIRVPGEGLLRVDE
MUL_3581|M.ulcerans_Agy99 DPITVLIATGVRRSELLALRWTDFDESKQTIAATGN--------------
Mb1727|M.bovis_AF2122/97 SD----GPLTLRNRAVLELLYSTGARISEAVGLDLDDIDTHARSVLLRGK
MLBr_01365|M.leprae_Br4923 AD----GPLVLRNRALLELLYSTGSRISEAVGLDVDDVDTQARTVLLQGK
TH_1542|M.thermoresistible__bu SD----GPLTLRNRALLELLYSTGARISEAVGLDIDDVDTVARSVLLRGK
Mflv_2786|M.gilvum_PYR-GCK AACWLLTLAGLRRSEVLGLRWSDVDLDGGTVTIAQGRVVAEGQGTITGDP
Mvan_3747|M.vanbaalenii_PYR-1 AACWLLTLAGLRRSEVLGLRWSDVDLDGGTVTIAQGRVVAEGQGTITGDP
MAV_0253|M.avium_104 AAAWRLALMGLRRGEILGLSWDSVDLDAGLLTVRANRAPVPG-GVEVGSP
Rv2659c|M.tuberculosis_H37Rv AFVLMAAWLAMRYGELTELRRKDIDLHGEVARVRRAVVRVGEGFKVTTPK
MAB_1816c|M.abscessus_ATCC_199 AKTA---------AGMRTVALPSFAVTALRHRQGRDYVGQQLMIFPSTAG
MSMEG_5599|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3607|M.marinum_M TKSA---------AGRRTIPLPKFAVDVLGKRRQLPYLGEQVVIFPSTAG
MUL_3581|M.ulcerans_Agy99 --------------------------------------------------
Mb1727|M.bovis_AF2122/97 GGKQ--RLVPVGRPAVHALDAYLVRGRPDLARRGRG---TAAIFLNARGG
MLBr_01365|M.leprae_Br4923 GGKQ--RLVPVGRPAVQALDAYLVRGRSDLARRGPGMLATPAIFLNARGG
TH_1542|M.thermoresistible__bu GGKQ--RLVPIGRPAVSALDAYLVRGRPELVRRGRG---TPAIFLNARGG
Mflv_2786|M.gilvum_PYR-GCK KSKRSRRALPMPAEVLAALRAFRLRQSEERLAIGSEYPDTGLVAVNVIGL
Mvan_3747|M.vanbaalenii_PYR-1 KSKRSRRALPMPAEVLAALRVFRLRQSEERLAIGSEYPDTGLVAVNVIGL
MAV_0253|M.avium_104 KTAAGLRTLPMPAELTVAMKQARKQQRERRLALGSKWVESGLVVVGEDGA
Rv2659c|M.tuberculosis_H37Rv SDAG--------VRDISIPPHLIPAIEDHLHKHVNPGRESLLFPSVNDPN
MAB_1816c|M.abscessus_ATCC_199 TWRDPNNFGKQWRAVRDDLGVPGVTTHSFRKTMATLIDDNGLSARVGADQ
MSMEG_5599|M.smegmatis_MC2_155 --------------------------------MP--------VARIGADH
MMAR_3607|M.marinum_M TLRDPNNFGKEWRTAREELGVAEVTTHSFRKTVATLIDDEGLSARIGADH
MUL_3581|M.ulcerans_Agy99 ------------------------------------------VVRVLPGL
Mb1727|M.bovis_AF2122/97 RLSRQSAWQVLQDAAERAGITAGVSPHMLRHSFATHLLEGGADVRVVQEL
MLBr_01365|M.leprae_Br4923 RLSRQSAWQVLQDAAEHAGITSGVSPHMLRHSFATHLLEGGADIRVVQEL
TH_1542|M.thermoresistible__bu RLSRQSAWQVLQDAAERAGIKAGVSPHTLRHSFATHLLDGGADVRVVQEL
Mflv_2786|M.gilvum_PYR-GCK PIRPETYSGEFMRHAKDAGVPL-IRLHDVRHTAATMLLDRGTTPSATAKW
Mvan_3747|M.vanbaalenii_PYR-1 PIRPETYSGEFMRHAKDAGVPL-IRLHDVRHTAATMLLDRGTTPSATAKW
MAV_0253|M.avium_104 PPHPDTLSHVWAETIAAHKLPA-VRLHDARHTCATLMHQDGVPLAVISAW
Rv2659c|M.tuberculosis_H37Rv RHLAPSALYRMFYKARKAAGRPDLRVHDLRHSGAVLAASTGATLAELMQR
MAB_1816c|M.abscessus_ATCC_199 LGHA-KVSMTQDRYMARGKVHHEVADLLDAT--ISDE-----
MSMEG_5599|M.smegmatis_MC2_155 LGHS-RISMTQDKHMARGRVHTVVADLLDRT--INDE-----
MMAR_3607|M.marinum_M LGHS-HVSMTQDRYMTRGRIHTQVAHLLDRAVRINDE-----
MUL_3581|M.ulcerans_Agy99 LGSR-RVPAVDGTTAVISPMHG--------------------
Mb1727|M.bovis_AF2122/97 LGHA-SVTTTQIYTLVTVHALREVWAGAHPRAR---------
MLBr_01365|M.leprae_Br4923 MGHA-SVTTTQIYTLVTVQALREVWAGAHPRAK---------
TH_1542|M.thermoresistible__bu LGHA-SVTTTQIYTMVTVHALREVWAGAHPRAR---------
Mflv_2786|M.gilvum_PYR-GCK LGHD-PAITLRVYGHVYDGALAAAG---DTLLRGH-------
Mvan_3747|M.vanbaalenii_PYR-1 LGHD-PAITLRVYGHVYDGALAAAG---DTLLRGH-------
MAV_0253|M.avium_104 LGHTNAAFTLATYGHSSDDSLAAAAQRLDALTGGKATPAEAK
Rv2659c|M.tuberculosis_H37Rv LGHS-TAGAALRYQHAAKGRDREIAALLSKLAENQEM-----
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