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MLATLSQIRAWSTEHLIDAAGYWTETADRWEDVFLQMRNQAHAIAWNGAGGDGLRQRTRADFSTVSGIAD QLRRAATIARNGAGTIDAAQRRVMYAVEDAQDAGFNVGEDLSVTDTKTTQPAAVQAARLAQAQALAGDIR LRVGQLVAAENEVSGQLAATTGDVGNVRFAGAPVVAHSAVQLVDFFKQDGPTPPPPGAPHPSGGADGPYS DPITSMMLPPAGTEAPVSDATKRWVDNMVNELAARPPDDPIAVEARRLAFQALHRPCNSAEWTAAVAGFA GSSAGVVGTALAIPAGPADWALLGAALLGVGGSGAAVVNCATK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2102c | - | - | 100% (323) | transmembrane protein |
| M. bovis AF2122 / 97 | Mb1984c | - | 2e-29 | 53.33% (135) | hypothetical protein Mb1984c |
| M. bovis AF2122 / 97 | Mb1985c | - | 3e-19 | 71.70% (53) | hypothetical protein Mb1985c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1972 | - | 5e-20 | 37.28% (169) | hypothetical protein Mflv_1972 |
| M. tuberculosis H37Rv | Rv2077c | - | 0.0 | 100.00% (323) | transmembrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0016 | - | 1e-13 | 26.47% (170) | hypothetical protein MAB_0016 |
| M. marinum M | MMAR_4061 | - | 6e-67 | 47.16% (335) | hypothetical protein MMAR_4061 |
| M. avium 104 | MAV_0692 | - | 5e-67 | 66.84% (196) | hypothetical protein MAV_0692 |
| M. smegmatis MC2 155 | MSMEG_5600 | - | 4e-22 | 33.87% (186) | hypothetical protein MSMEG_5600 |
| M. thermoresistible (build 8) | TH_3926 | - | 4e-25 | 33.50% (200) | PUTATIVE putative hypothetical protein Mvan_5711 |
| M. ulcerans Agy99 | MUL_1136 | - | 1e-51 | 48.28% (232) | hypothetical protein MUL_1136 |
| M. vanbaalenii PYR-1 | Mvan_5711 | - | 2e-18 | 31.46% (178) | hypothetical protein Mvan_5711 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2102c|M.bovis_AF2122/97 -----------MLATLSQIRAWSTEHLIDAAGYWTETADRWEDVFLQMRN
Rv2077c|M.tuberculosis_H37Rv -----------MLATLSQIRAWSTEHLIDAAGYWTETADRWEDVFLQMRN
MAV_0692|M.avium_104 -----------MPATLSQIQAWSTEHLIDAAAYWTQTADRWEDAFLTMRN
MMAR_4061|M.marinum_M -----------MPATLSQIRAWSTEHLIDSAGYWTKTADRWEDTFFQIRN
MUL_1136|M.ulcerans_Agy99 -----------MVLTLSQVQAWRTEHLIEAATYWSKTADQWEDVFLQMRN
Mflv_1972|M.gilvum_PYR-GCK ------------MPSRSEVESWETADLDAAASRWRTAGDVLESAFEQHRQ
MSMEG_5600|M.smegmatis_MC2_155 MSPTATPAEGGEGLSRSRIESWDTTHLENATARWRATATELEGHFEQLRQ
TH_3926|M.thermoresistible__bu ---MIDALPASGLPTLSQIQGWQTAHLRSAARRWRVTADTWTSIYDDIAA
Mvan_5711|M.vanbaalenii_PYR-1 -----MSVVAHGLPTLSQIENWETAHLACAARRWTAAAEHWESSFGLIAD
MAB_0016|M.abscessus_ATCC_1997 ------------MPTKSEILNWRTDHLGAAAKTWGDQATQLDTAVNGAQG
: *.: * * .* :: * .
Mb2102c|M.bovis_AF2122/97 ---QAHAIAWNGAGGDGLRQRTRADFSTVSGIADQLRRAATIARNGAGTI
Rv2077c|M.tuberculosis_H37Rv ---QAHAIAWNGAGGDGLRQRTRADFSTVSGIADQLRRAATIARNGAGTI
MAV_0692|M.avium_104 ---QAQSITWHGAGGDALRQRTGADVSVVSGKADQLRQAAGIARNGASEI
MMAR_4061|M.marinum_M ---QSYALDWNGAGGAALRERTSADLPLVSAKADVLRQAAGIARDGASGI
MUL_1136|M.ulcerans_Agy99 ---QSHTLVWEGAGGDALRQRTGADLAIVSTKADELRQASKIARDGAGTI
Mflv_1972|M.gilvum_PYR-GCK NILTPGGTAWEGDAKDAALDRVTADTSVVRRQGDVHRVAADIAARGSEDI
MSMEG_5600|M.smegmatis_MC2_155 HVLAPGGTEWEGDAKDAALERATQNLNTVRAAGDIARSAADLAENSSADI
TH_3926|M.thermoresistible__bu DLSAKSEIVWEGDASTAAQARTKRDRDTVELLAERLYFGASIAESGAAMV
Mvan_5711|M.vanbaalenii_PYR-1 GVRSPHGTQWEGAAQAAAQARADSDLAGVRMLADRLRTAARTAVDGGSAI
MAB_0016|M.abscessus_ATCC_1997 ---LLDGLRGSGQFVEAFRTRLKSYIDKTRPKVDKLKSAKQVAESSEQQL
* . * . : . * . :
Mb2102c|M.bovis_AF2122/97 DAAQRRVMYAVEDAQDAGFNVGEDLSVTDTKTTQPAAVQAARLAQAQALA
Rv2077c|M.tuberculosis_H37Rv DAAQRRVMYAVEDAQDAGFNVGEDLSVTDTKTTQPAAVQAARLAQAQALA
MAV_0692|M.avium_104 SAAQRRVLYGVEDAQNAGFTVGEDLSVTDTRSTSP-AERAARQAQAEAFA
MMAR_4061|M.marinum_M SAAQRRVLYAIEDAQNVGFTVGEDLSVTDTRSSGTAAEQVARHAQAQAFA
MUL_1136|M.ulcerans_Agy99 GIAQRRVLHAVEDAHNAGFTVGEDFSVTDIRTSRRSAEQAARQAQAQAQA
Mflv_1972|M.gilvum_PYR-GCK QGARSRVLEAIAEAEQDDFTVGEDLSVTDNR-AYDLETAAARMTAATEHA
MSMEG_5600|M.smegmatis_MC2_155 SAAKRDALQSISDAEADGFEVNEDLSVRDTS-RVDVSTMAARYTAAREHA
TH_3926|M.thermoresistible__bu DQAKEEALLVVRVAGALAFDVREDLSLVDRLATGSPAATAVRLQQSNVLA
Mvan_5711|M.vanbaalenii_PYR-1 EAAKHEALTVIAATNAMGFEVADDLTVWNRMG------AALRRNDAELLG
MAB_0016|M.abscessus_ATCC_1997 KGAKDKAVYAVHDPEDEDFNVNEDLSVTERRSHSG-LDRLKRAIRRRWLQ
*: .: : . * * :*::: : *
Mb2102c|M.bovis_AF2122/97 GDIRLRVGQLVAAENEVSGQLAATT---------GDVGNVRFAGAPVVAH
Rv2077c|M.tuberculosis_H37Rv GDIRLRVGQLVAAENEVSGQLAATT---------GDVGNVRFAGAPVVAH
MAV_0692|M.avium_104 ADLRLRAEQLEAADTKAAGQITATA---------GDVGNATFT--PAHNG
MMAR_4061|M.marinum_M GDIRLRAEQLDAAEVKVAGQLSAIR---------AGLSGIGFAENPIFNP
MUL_1136|M.ulcerans_Agy99 QATDIRQRAVEPVPPPAPGRLPPLTP--------GEMATPRLPAPPPQPP
Mflv_1972|M.gilvum_PYR-GCK EFIRWRVEQLVATDALIGQQLQANA---------AELEGIRFEGDRDGNG
MSMEG_5600|M.smegmatis_MC2_155 ENIQWNANQLLATDTLIGRRLTAKA---------AELNGVRFDDEPEG--
TH_3926|M.thermoresistible__bu ATVRVGAAQLVSTDHAVAQRLREAT---------DDFDSFDFARNPIIQP
Mvan_5711|M.vanbaalenii_PYR-1 ISVRTGAAQLAAVDHAVATELDSVT---------AGFDALNIGEGPVIAP
MAB_0016|M.abscessus_ATCC_1997 GILHTRAQELVATDNAIARKLHEIAQDLSNFHLEGPDGNTDFSGDPNHPK
: .. .: :
Mb2102c|M.bovis_AF2122/97 SA-----------------------------------------------V
Rv2077c|M.tuberculosis_H37Rv SA-----------------------------------------------V
MAV_0692|M.avium_104 NG-----------------------------------------------V
MMAR_4061|M.marinum_M VAH---------------------------------------APANRIGI
MUL_1136|M.ulcerans_Agy99 IR------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK TDPTIRLVDNKTEDKGSQAESSEQRGAGSLSEESTGTWQDMLAPEESAES
MSMEG_5600|M.smegmatis_MC2_155 ---------------------------------------------TIRAA
TH_3926|M.thermoresistible__bu LSTD--------------------------------------SDEHHFGT
Mvan_5711|M.vanbaalenii_PYR-1 IAAG--------------------------------------DDGQSFGQ
MAB_0016|M.abscessus_ATCC_1997 IMGPAKPLG----------------------------------PIEQEDY
Mb2102c|M.bovis_AF2122/97 QLVDFFKQDGPTPPPPG----APHPSGGADGPYSDPITSMMLPPAGTEA-
Rv2077c|M.tuberculosis_H37Rv QLVDFFKQDGPTPPPPG----APHPSGGADGPYSDPITSMMLPPAGTEA-
MAV_0692|M.avium_104 QLVD-FKQDG--------------------GPVCD---------------
MMAR_4061|M.marinum_M QPVD-FKQDSGAPPPFAPWDTADETPPPGKGPFNRMLLPSSTPPLEPDD-
MUL_1136|M.ulcerans_Agy99 GGADLAPAEP----------------------------------------
Mflv_1972|M.gilvum_PYR-GCK AEGADTAESPLEALLGEGETAEGQQRSSLDEALTEVAGKPVDAPPTALER
MSMEG_5600|M.smegmatis_MC2_155 SFGDGFKQSPFDDLLT-----KEQALAAWEKLQTDIASYNSRCAVNIVG-
TH_3926|M.thermoresistible__bu CFAESFKEDVG---------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 CFADRFKDDIG---------------------------------------
MAB_0016|M.abscessus_ATCC_1997 DLGYTFLDENGNPLPMLDENGNVVIDPKTGRPVPDSVWGDPADNNADGSP
.
Mb2102c|M.bovis_AF2122/97 -------------------PVSDATKRWVDN-------------------
Rv2077c|M.tuberculosis_H37Rv -------------------PVSDATKRWVDN-------------------
MAV_0692|M.avium_104 --------------------DPDYNDRFFRK-------------------
MMAR_4061|M.marinum_M -------------------PLNDALRRITNSPAR----------------
MUL_1136|M.ulcerans_Agy99 ---------------------PPVVRTPMEP-------------------
Mflv_1972|M.gilvum_PYR-GCK ILSQHTGTGRGEDRRYTQHPLEAPIVGADSSVIGDQQARVDAAHESVESA
MSMEG_5600|M.smegmatis_MC2_155 -------------------PLPPPQYAACQQELAFLQG------------
TH_3926|M.thermoresistible__bu ---------------------KNMVQGVFVG-------------------
Mvan_5711|M.vanbaalenii_PYR-1 ---------------------ENMVQGVFVG-------------------
MAB_0016|M.abscessus_ATCC_1997 RVPHPP-----RDHHFADMDANDPYRTLPTGTTVGPNG------------
Mb2102c|M.bovis_AF2122/97 ------MVNELAARPPDDPIAVEARRLAFQALHRPCNSAEWTAAVAGFAG
Rv2077c|M.tuberculosis_H37Rv ------MVNELAARPPDDPIAVEARRLAFQALHRPCNSAEWTAAVAGFAG
MAV_0692|M.avium_104 ------FMGRVGAG----------------------------AAIGGLAG
MMAR_4061|M.marinum_M ------PAGPLTQDQIKALVDAEVNDKLSQAEKFSLRTLLSKTFEGCGAG
MUL_1136|M.ulcerans_Agy99 -----------------------------------------PARLGGPIA
Mflv_1972|M.gilvum_PYR-GCK QGALDDALAQSTVAGAGAGPGRDQLDALGHVLFEARGEVTSQTEVLEKLN
MSMEG_5600|M.smegmatis_MC2_155 ----QEAALRARLADFGIHPG----------------EAPSSTSSGGDLT
TH_3926|M.thermoresistible__bu ------------------------------------------GAIGAARG
Mvan_5711|M.vanbaalenii_PYR-1 ------------------------------------------GALGALRG
MAB_0016|M.abscessus_ATCC_1997 -----ERIALVSRPPDDPAWAENQTKNGKSVYVTQTEAYDVTRQPPQSLG
Mb2102c|M.bovis_AF2122/97 SSAGVVGTA-------------LAIPAGPADWALLGAALLGVGGSGAAVV
Rv2077c|M.tuberculosis_H37Rv SSAGVVGTA-------------LAIPAGPADWALLGAALLGVGGSGAAVV
MAV_0692|M.avium_104 APEAGVG----------------AIPGAIIGGAAGGIEAFIEGATESEPP
MMAR_4061|M.marinum_M GIAAGVGGL-------------ITGPLEPLDIAG-GCAAGAIGDGGKYLF
MUL_1136|M.ulcerans_Agy99 GGPVPPGS--------------IPHPVQPPHSHHGPPVLGKDELPDLGEF
Mflv_1972|M.gilvum_PYR-GCK AAADEVGQGRVPIPALPENADVQAFPAEPSAFTEGSRALSEGSFGLIPDV
MSMEG_5600|M.smegmatis_MC2_155 ATATQIG------------AEIATFPPGTRADALAERMTGLHLNQADAAR
TH_3926|M.thermoresistible__bu ALMGILGGP------------IGVFGGGVLGFVGGAAGGALISGPARTAV
Mvan_5711|M.vanbaalenii_PYR-1 AVLGVLGGP------------LGMLGGSVAGFVGGAAGGAMISGPARTAV
MAB_0016|M.abscessus_ATCC_1997 KLQGVDGSKVYQGSIVYDKASGRMYVVGNHGDGSGDTARGMWRSDPVDPN
*
Mb2102c|M.bovis_AF2122/97 NCATK---------------------------------------------
Rv2077c|M.tuberculosis_H37Rv NCATK---------------------------------------------
MAV_0692|M.avium_104 KCGK----------------------------------------------
MMAR_4061|M.marinum_M EYGGK---------------------------------------------
MUL_1136|M.ulcerans_Agy99 NPG-----------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK AHDIDVFRNWSEASSDDRAGAVLDVAGAAPIP-GGKLVTEGLEHAVDAVN
MSMEG_5600|M.smegmatis_MC2_155 ATDIAAARIWGETG------------GTSKMPDGSIIVLPANIRQTDVMK
TH_3926|M.thermoresistible__bu TSAWDCL-------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 TSAWDCL-------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 HPNDWVKTLRYQGDVPSLPGSRESSLVALPHGGVALFGADDYAPAEGRNM
Mb2102c|M.bovis_AF2122/97 --------------------------------------------------
Rv2077c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_0692|M.avium_104 --------------------------------------------------
MMAR_4061|M.marinum_M --------------------------------------------------
MUL_1136|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK AGRHVDDALDAGSAGAHHLPDVPSAPHVDQTPDVGGPHGGGGADAGPVGN
MSMEG_5600|M.smegmatis_MC2_155 VFPDGSVTVLRGVDVTQYLPR-----------------------------
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 AVGAISAATPEGLLQARPVTDLLPAGKTPWPGGAPYAALPTGVHWDPALR
Mb2102c|M.bovis_AF2122/97 --------------------------------------------------
Rv2077c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_0692|M.avium_104 --------------------------------------------------
MMAR_4061|M.marinum_M --------------------------------------------------
MUL_1136|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK FGFEDANALLQSSEANGGHLIERHVGMTSDDLAARMESSGLQTVSTFATA
MSMEG_5600|M.smegmatis_MC2_155 --------------------------------------------------
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 ADVVDTRVSIWRDVPGVRGAYPPVTYQTSVPIFQPNS-------------
Mb2102c|M.bovis_AF2122/97 --------------------------------------------------
Rv2077c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_0692|M.avium_104 --------------------------------------------------
MMAR_4061|M.marinum_M --------------------------------------------------
MUL_1136|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK DEAASAVSTALRENQDVLNSWIAEGAPRKLELEAPFDGGAVLVQGATEAV
MSMEG_5600|M.smegmatis_MC2_155 --------------------------------------------------
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2102c|M.bovis_AF2122/97 --------------------------
Rv2077c|M.tuberculosis_H37Rv --------------------------
MAV_0692|M.avium_104 --------------------------
MMAR_4061|M.marinum_M --------------------------
MUL_1136|M.ulcerans_Agy99 --------------------------
Mflv_1972|M.gilvum_PYR-GCK TGSTVRVVLKGDGNGGWYVLTGFPKP
MSMEG_5600|M.smegmatis_MC2_155 --------------------------
TH_3926|M.thermoresistible__bu --------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------
MAB_0016|M.abscessus_ATCC_1997 --------------------------