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MTGTDAGGHPSDPAVTENESYEVLRRLQGPHRNSTSSTGGVGEFSGITITNAVPELADLGFVDAYEVGRG GYGVVYRCLQAELGRVVAVKTLTADVDEWGPRFLREEQAMARLTAHPNIVPVLQVGQTASGVPFLVMPFC GRGSVQQRIERYGVLAVEEVLRIGVKIAAALESAHRVGVVHRDVKPANVLLTDYGEPALCDFGIARMEAG FETGPGMFVGSPAYTAPELLAGESPNAASDVYALGASLFAGLTGHAAFERRNGEQVVAQFLRIANESIPD LRDNNIPTQVADVVNAAMAREPGDRPSALKLGEMIQQAQADLGLAVDAMALPEANGEEGIRSARRIPTGA RSGAERYGPGRVPVLPAGLVGRRDELAQLRKSLYSSRLVTVTGMGGVGKTTLAIAAAGQLRAEFSDQVWL VELSELRDGDMLAEVAIAALGVCDQTGAPPTDVLVEFLGHGMTLLVIDNCEQIIDAVAKQVDNLLHHCPQ LHILATSREVLDIDGESVLPLMPLAVPETDADSTLGSLARYDAVELFVARARAGVPEFRLTHANAAAVAR VCARLDGLPLAIELAAARLRALSIEQIADGLADRYRLLSRGHRGAPTRQQNLVSCVAWSHDLCTPTEQHL WAILSVFAGSFDLPAARHVSAGSLLDEQCLDVMCTLVDKSILIRTEHDGQVRFRLLDTLRDYGRTHLSAA EHHQLRHRHADYYHRLAAQAYSDWFGPQQIEWLSRLTAETPNLREALQFCITHEPATALELAANLREIWI PRGMFSEGYRWLDLALTALPPLPSPERIRALAHISEFANFRGNLPRATELVAQARQLYESLADRRVIAVL ECTDGHMAMINGDFERARDCLRRAASATDDLQSKGCAMLLMGWDSLFWGDVEKASDWFEKALAVSESHGE SLQRSYVLVCTGISSWRRGEFERAEQQLQQGIQICRALNDRWMAAQYFEALAWCAGSNEDFRRAVVLMAA ANVLSPATGFPLMALFSGLHDECEQRSRAGLDDAEYQAAWNQGSALSFQQAVMVAMGE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3547 | - | - | 100% (1038) | serine/threonine-protein kinase transcriptional regulatory protein |
| M. marinum M | MMAR_0366 | pknK_3 | 0.0 | 50.97% (983) | serine/threonine-protein kinase transcriptional regulatory |
| M. marinum M | MMAR_0365 | pknK_2 | 0.0 | 48.04% (997) | serine/threonine-protein kinase transcriptional regulatory |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3107c | pknK | 2e-94 | 40.49% (573) | serine/threonine-protein kinase transcriptional regulatory |
| M. gilvum PYR-GCK | Mflv_5210 | - | 4e-32 | 34.18% (316) | protein kinase |
| M. tuberculosis H37Rv | Rv3080c | pknK | 8e-95 | 40.49% (573) | serine/threonine-protein kinase transcriptional regulatory |
| M. leprae Br4923 | MLBr_01753 | - | 2e-64 | 35.90% (493) | putative transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1988c | - | 2e-28 | 31.20% (391) | serine/threonine protein kinase |
| M. avium 104 | MAV_2318 | - | 7e-33 | 32.46% (342) | serine-threonine protein kinase |
| M. smegmatis MC2 155 | MSMEG_0529 | - | 3e-83 | 37.59% (580) | serine/threonine-protein kinase PknK |
| M. thermoresistible (build 8) | TH_2610 | - | 3e-29 | 32.08% (293) | PUTATIVE serine/threonine protein kinase |
| M. ulcerans Agy99 | MUL_4753 | pknK_3 | 0.0 | 50.66% (983) | serine/threonine-protein kinase transcriptional regulatory |
| M. vanbaalenii PYR-1 | Mvan_5928 | - | 2e-82 | 36.24% (596) | regulatory protein, LuxR |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3547|M.marinum_M MTGTDAGGHPSDPAVTENESYEVLRRLQGPHRNSTSSTGGVGEFSGITIT
MUL_4753|M.ulcerans_Agy99 --------------------------------------------------
MAV_2318|M.avium_104 -----------------------MAQAESPGSSSGRPGPHRRQAQAESPG
TH_2610|M.thermoresistible__bu --------------------------VETYQQSD----------------
MAB_1988c|M.abscessus_ATCC_199 --------------------------MTSPKSPTGR------------LD
Mb3107c|M.bovis_AF2122/97 -------------------------MTDVDPHATRR----------DLVP
Rv3080c|M.tuberculosis_H37Rv -------------------------MTDVDPHATRR----------DLVP
MSMEG_0529|M.smegmatis_MC2_155 -------------------------MVRNDPLPTQR----------DLPA
MLBr_01753|M.leprae_Br4923 -----------------MYSLGEMQKPVPVGADYLASCLVARLRSTDVPT
Mvan_5928|M.vanbaalenii_PYR-1 -----------------------MSELVPTG-------------------
Mflv_5210|M.gilvum_PYR-GCK --------------------------MSTPQGGARLG-------------
MMAR_3547|M.marinum_M NAVPELADLGFVDAYEVGRGGYGVVYRCLQAELGRVVAVKTLTADVDEWG
MUL_4753|M.ulcerans_Agy99 -------MDGFADAAEVGRGGFGVVYRCRQVDLDRVVAIKVLTIDLDENR
MAV_2318|M.avium_104 SFAGTLLDGRYLIESKIASGGTSTVYRGVDTRLDRPVAVKVMDPRYAGDE
TH_2610|M.thermoresistible__bu PFAGTVLDGRYRIDTLIATGGMSAVYRGLDLRLDRPVAVKVMDSRYAGDQ
MAB_1988c|M.abscessus_ATCC_199 PMIGAVLDGRYRIEAPIATGGMSTVYRGLDTRLDRPVAVKVMDSRYASDS
Mb3107c|M.bovis_AF2122/97 NIPAELLEAGFDNVEEIGRGGFGVVYRCVQPSLDRAVAVKVLSTDLDRDN
Rv3080c|M.tuberculosis_H37Rv NIPAELLEAGFDNVEEIGRGGFGVVYRCVQPSLDRAVAVKVLSTDLDRDN
MSMEG_0529|M.smegmatis_MC2_155 GIPAELVAAGFEDPDEIGRGGFGVVYRCVQRALDRTVAVKVLTTDLEPDN
MLBr_01753|M.leprae_Br4923 DLHRGCTVTLFLGDVEGLAELSETQPDEAADAIARLDCVVSEAVAAHGGV
Mvan_5928|M.vanbaalenii_PYR-1 ------TVTLLLADVQGSTQLWETQPETMTAAVAQLDRTLTDLVSDHDGV
Mflv_5210|M.gilvum_PYR-GCK -----TRFGPYELHSVIGVGGMGEVYRAYDTARERMVAIKLLRPEMAADH
:
MMAR_3547|M.marinum_M ---PRFLREEQAMARLTAHPNIVPVLQVG--QTASGVPFLVMPFCGRGSV
MUL_4753|M.ulcerans_Agy99 ---PRFEREQRAMAKLTGHPNIVSVLQIG--ETRDGHPYLVMPYCRRGSV
MAV_2318|M.avium_104 QFLTRFQREARAVARLK-DPGLVAVYDQG--LDARHP-FLVMELIEGGTL
TH_2610|M.thermoresistible__bu QFLTRFQREARAAARLK-DPGLVAVYDQGPGSPASHPPYLVMELIEGGTL
MAB_1988c|M.abscessus_ATCC_199 GFLARFRLEARAVARLR-HPGLVAVFDQG--MDGRHP-FLVMELIDGGTL
Mb3107c|M.bovis_AF2122/97 --LERFLREQRAMGRLSGHPHIVTVLQVG--VLAGGRPFIVMPYHAKNSL
Rv3080c|M.tuberculosis_H37Rv --LERFLREQRAMGRLSGHPHIVTVLQVG--VLAGGRPFIVMPYHAKNSL
MSMEG_0529|M.smegmatis_MC2_155 --LERFMREQVAMGKLSGHPNIVNIFQVG--TIASGRPYIVMQYHPHGSL
MLBr_01753|M.leprae_Br4923 QQVVQGVRGNFLATFARASDATACALDLQLAPIVPVRFRIALHTGEVQIS
Mvan_5928|M.vanbaalenii_PYR-1 RPVEQGEGDSFVVAFTRASDAVACALALQRAPLAPIRLRIGVHTGEVRLR
Mflv_5210|M.gilvum_PYR-GCK SFQERFRRESRVAARLQ-EPHVIPVHNFG---EIDGVLYIDMRLVEGASL
: : :
MMAR_3547|M.marinum_M QQRIERYGVLAVEEVLRIGVKIAAALESAHRVGVVHRDVKPANVLLTDYG
MUL_4753|M.ulcerans_Agy99 QTEISRLGRLSLADILQLGVALAAGLESAHRLDILHRDIKPANVLLTDFG
MAV_2318|M.avium_104 RELLGERGPMPPYAVAAVLRPVLGGLAAAHRAGLVHRDVKPENVLISDDG
TH_2610|M.thermoresistible__bu RELLRERGPMPPHAAAAVLAPVLGGLAVAHRAGLVHRDIKPENVLISDDG
MAB_1988c|M.abscessus_ATCC_199 RELLRERGPMPPHAVAAVFNPLLGGLAVAHRSGLVHRDVKPENVLISDDG
Mb3107c|M.bovis_AF2122/97 ETLIRRHGPLDWRETLSIGVKLAGALEAAHRVGTLHRDVKPGNILLTDYG
Rv3080c|M.tuberculosis_H37Rv ETLIRRHGPLDWRETLSIGVKLAGALEAAHRVGTLHRDVKPGNILLTDYG
MSMEG_0529|M.smegmatis_MC2_155 SAKIQAAGPLGWRGALRIGVKMAGALETAHQRDTLHRDVKPANILLTEYG
MLBr_01753|M.leprae_Br4923 NDDVNNVVFMMVQAAGLLDLACGGQTVLSSITGDLVVDGLPADTWLVDLG
Mvan_5928|M.vanbaalenii_PYR-1 -DEGNYVGPTINRTARLRELAHGGQTVLSGTTSDLVADLLPDGGWLSDLG
Mflv_5210|M.gilvum_PYR-GCK KEVLRSDGPLQPARAVSIIRQVAAALDDAHANGLVHRDIKPENVLLTGDD
. : . : * * . : .
MMAR_3547|M.marinum_M EPALCDFGIAR-MEAGFETGPG---------MFVGSPAYTAPELLAGESP
MUL_4753|M.ulcerans_Agy99 EPALTDFGLAH-MAGGFRTATG---------LFTASPAFTASELARGGEP
MAV_2318|M.avium_104 EVKIADFGLVRAVAAAGITSAS---------VILGTAAYLSPEQVRDGAA
TH_2610|M.thermoresistible__bu EVKIADFGLVRAVAEAKITSDS---------VILGTAAYLSPEQVATGDA
MAB_1988c|M.abscessus_ATCC_199 EVKLADFGLVRAVAEAGITSTS---------VILGTAAYLSPEQVRTGSA
Mb3107c|M.bovis_AF2122/97 EPQLTDFGIAR-IAGGFETATG---------VIAGSPAFTAPEVLEGASP
Rv3080c|M.tuberculosis_H37Rv EPQLTDFGIAR-IAGGFETATG---------VIAGSPAFTAPEVLEGASP
MSMEG_0529|M.smegmatis_MC2_155 EPQLTDFGIAR-IAGGFETAEG---------AIMGSPAYTAPEVLLGESP
MLBr_01753|M.leprae_Br4923 SHLLRDLARPVRVMQLCHRNLRRNLHELGIRTVPGGPSLPVPLTTFVGRA
Mvan_5928|M.vanbaalenii_PYR-1 THRLRDLPRPERVVQLCHADLSNEFPPLRAREEIGVQRLPAQLTSFVGRV
Mflv_5210|M.gilvum_PYR-GCK FAYLVDFGIAHGGGEASVTSTG---------LVVGSSAYMAPERFSGERG
: *: .
MMAR_3547|M.marinum_M NAASDVYALGASLFAGLTGHAAFERRNGEQVVAQFLRIANESIPDLRDNN
MUL_4753|M.ulcerans_Agy99 DRASDVYGVGATLFCALTGHPPFERRKGESVIAQILRVANDPVPDLAEYD
MAV_2318|M.avium_104 TPRSDVYAAGILAYELLTGRTPFTG-DSTLAIAYRRLDADVPPPSAAIDG
TH_2610|M.thermoresistible__bu TPRSDVYAVGILTYEMLTGNTPFTG-DNALALAYQRLDNDVPPPSSAISG
MAB_1988c|M.abscessus_ATCC_199 GPRSDVYSAGILMYELLTGSTPFTG-DTPLALAYQRIDRDVQAPSEAIDG
Mb3107c|M.bovis_AF2122/97 TPASDVYSLGATLFCVLTGHAAYERRSGERVIAQFLRITSQPIPDLRKQG
Rv3080c|M.tuberculosis_H37Rv TPASDVYSLGATLFCALTGHAAYERRSGERVIAQFLRITSQPIPDLRKQG
MSMEG_0529|M.smegmatis_MC2_155 TVASDVYSLASTVFTASTGHAVFERGKGEQMVAQFLRITRHPAPNLRDAD
MLBr_01753|M.leprae_Br4923 AQIKELQELLTEKRLLTLVGPGGVGKTRLALQVVARVADEFSGELSYFDL
Mvan_5928|M.vanbaalenii_PYR-1 DDMAQVRGLMDANRLVTLTGAGGVGKTRLATQVAVAVVEGYPGGVWYVDL
Mflv_5210|M.gilvum_PYR-GCK GPASDIYSLACLLYESLTGRAPFEAADVRQVWSAHMFAAP-PRPSIMRRG
:: .
MMAR_3547|M.marinum_M IPTQVADVVNAAMAR-------------EPGDRP-SALKLGEMIQQAQAD
MUL_4753|M.ulcerans_Agy99 VAEDVASVVNRALSR-------------DPAARP-TMVELGEAIQSLQAA
MAV_2318|M.avium_104 VPAQFDDFVQRATAR-------------DPADRYADAVEMGADLDAIADE
TH_2610|M.thermoresistible__bu VPPQFDELVATATAR-------------DPADRFADAHDMAAAVADLVAE
MAB_1988c|M.abscessus_ATCC_199 VPEEFDELVLRATSR-------------DPDARYADAAQFGAELDAISSE
Mb3107c|M.bovis_AF2122/97 LPADVAAAIERAMAR-------------HPADRPATAADVGEELRDVQRR
Rv3080c|M.tuberculosis_H37Rv LPADVAAAIERAMAR-------------HPADRPATAADVGEELRDVQRR
MSMEG_0529|M.smegmatis_MC2_155 LPADLSAAIEQAMSR-------------TISDRPESAQAFGEQLRELQRR
MLBr_01753|M.leprae_Br4923 APDTDHDIFPITVL--------------DNLRRCIGDRRMLMVLDNCEYL
Mvan_5928|M.vanbaalenii_PYR-1 APITDPALVAITVARALGLPDQPGRSTVDTIVRFIADRRMLVVLDNCEHL
Mflv_5210|M.gilvum_PYR-GCK VSRAFDDVIARGMAK-------------NPTERYATAGELARAAAAAASA
. . * .
MMAR_3547|M.marinum_M LGLAVDAMALPEANGEEGIRSARRIP--------TGARSGAERYGPGRVP
MUL_4753|M.ulcerans_Agy99 HGQAVDAMAL-----EGGKRSTSVSS--------ESAWHVSARQTRGNLP
MAV_2318|M.avium_104 LALPGFRVPAPRNSALHRSAALHR------------------------EA
TH_2610|M.thermoresistible__bu LELPPFRVPAPRNSAQHLSAIRQH------------------------SQ
MAB_1988c|M.abscessus_ATCC_199 LRLPPFRVPAPRDSKQHVAEQLYRSRLID-SGGNTTGNLSAPGQADAADA
Mb3107c|M.bovis_AF2122/97 NGVSVDEMPLPVELGVERRRSPEAHAAHRHTGGGTPTVPTPPTPATKYRP
Rv3080c|M.tuberculosis_H37Rv NGVSVDEMPLPVELGVERRRSPEAHAAHRHTGGGTPTVPTPPTPATKYRP
MSMEG_0529|M.smegmatis_MC2_155 HGLPVDDMPIPIAPPTDR---PSSIASPTPSSGYPVRTLTPPAPATRFQM
MLBr_01753|M.leprae_Br4923 LDVCANVMTTLLGACPSLTILATSREPIGVAGEVIWRVSMLSPADEAVEL
Mvan_5928|M.vanbaalenii_PYR-1 LDACATLIDALLGACPALAMLATSREPIAVAGEQTWRVPPLALDDDAIEL
Mflv_5210|M.gilvum_PYR-GCK APVAEPVPPVTPPSTRQFSGVHPAMTP-----------PPAPAPIAAARR
MMAR_3547|M.marinum_M VLPAGLVGRRDELAQLRKSLYSSRLVTVTGMGGVGKTTLAIAAAGQLRAE
MUL_4753|M.ulcerans_Agy99 AKLAGFVGRQAELAELGALISTSRPVTLTGVGGVGKTSLAVQAAGEHVSH
MAV_2318|M.avium_104 GRRAPGAEPPARHPTRHLTRGPEEWPQPEPPAHVGAEPDDDEDDYEYQSV
TH_2610|M.thermoresistible__bu SAR----------PTTTLQ----------PPXXXGAG-----GRARVATE
MAB_1988c|M.abscessus_ATCC_199 ASAAAALGVSARPSTPPRPRVPNPTRMMDPVPAYDAG--YDEEFDGEPDE
Mb3107c|M.bovis_AF2122/97 SVPTGSLVTRSRLTDILRAGGRRRLILIHAPSGFGKSTLAAQWREELSRD
Rv3080c|M.tuberculosis_H37Rv SVPTGSLVTRSRLTDILRAGGRRRLILIHAPSGFGKSTLAAQWREELSRD
MSMEG_0529|M.smegmatis_MC2_155 PSSAKRLVERARLIDVLRAQRDKKLTVIHGPTGFGKSTLAVQWAKQLAAD
MLBr_01753|M.leprae_Br4923 FTERAALVQPGFSVTDGNRQIVTEICQRLDGMPLAIELAAARIRTLSLTE
Mvan_5928|M.vanbaalenii_PYR-1 FTDRARRARPDFIISADDAAAVSEICHRLDGMPLAIELAAARVRALSLTE
Mflv_5210|M.gilvum_PYR-GCK PGRGQGALVAGIVVMFVAAAVLALVLVFTGGSDPQPPRIAAPPSSSSDTS
MMAR_3547|M.marinum_M FSD---QVWLVELSELRDGDMLAEVAIAALGVCDQTGAPPTDVLVEFLGH
MUL_4753|M.ulcerans_Agy99 FHD---GVWLVDIGELSDGALLAGLAARMLGIRDQGARPLTEVLTDALAE
MAV_2318|M.avium_104 TGE---FAGIPISEFVWARQHNRRMVLVWLALVLAVTGMVATAAWTIGRN
TH_2610|M.thermoresistible__bu IGD---RIGI-------------------VDQPPTARGRHANAVRTAFRN
MAB_1988c|M.abscessus_ATCC_199 SAF---FADIDDSDYRYERQQSRRAIFIWLVIVLILTSSVAAGCWSLGAN
Mb3107c|M.bovis_AF2122/97 GAA---VAWLTIDNDDNNEVWFLSHLLESIRRVRPTLAESLGHVLEEHGD
Rv3080c|M.tuberculosis_H37Rv GAA---VAWLTIDNDDNNEVWFLSHLLESIRRVRPTLAESLGHVLEEHGD
MSMEG_0529|M.smegmatis_MC2_155 GVA---VAWLTVDDDDNNVVWFLSHVIEAIRSVMPALASDLGDVLEEHGD
MLBr_01753|M.leprae_Br4923 IADGLDDRFRLLTGGARTAVRRQQTLRASMDWSYALLTESERALFRRLSA
Mvan_5928|M.vanbaalenii_PYR-1 IVDGLHDRFRLLTGGSRTAVRRQQTLRASVDWSHGLLTDPERVLFRRLAV
Mflv_5210|M.gilvum_PYR-GCK TPP---STSAVEGVSGTDSQGFVGHTARCDSGDTPAALIRTSLSLAIICD
MMAR_3547|M.marinum_M GMTLLVIDNCEQIIDAVAKQVDNLLHHCPQLHILATSREVLDIDGESVLP
MUL_4753|M.ulcerans_Agy99 RDALVIFDGCEHVIDHAAQLIDTLLQGCPQLHILATSRELLGIGGEAVLA
MAV_2318|M.avium_104 LNGLF---------------------------------------------
TH_2610|M.thermoresistible__bu DE------------------------------------------------
MAB_1988c|M.abscessus_ATCC_199 ITNLL---------------------------------------------
Mb3107c|M.bovis_AF2122/97 DAGRYVLTSLIDEIHENDDRIAVVIDDWHRVSDSRTQAALGFLLDNGCHH
Rv3080c|M.tuberculosis_H37Rv DAGRYVLTSLIDEIHENDDRIAVVIDDWHRVSDSRTQAALGFLLDNGCHH
MSMEG_0529|M.smegmatis_MC2_155 DAERYVLTSLINDIHSSGRRMTLVIDDWHRVTDPATIAALRYLLDNVASG
MLBr_01753|M.leprae_Br4923 ISGTFDLKVAYAVGHDDLEEPDQVFDRLTMLIDKSLVIVEGRQGGSRYRL
Mvan_5928|M.vanbaalenii_PYR-1 FAGGFDLDGAQAITVDGEVHRYEVVDLLTLLVDKSLLIAENTAGRTRYRL
Mflv_5210|M.gilvum_PYR-GCK RGDGDYYYRGERLRDGANREIDGARRSGDGFTVTGSDGARYDVQPDQLTI
MMAR_3547|M.marinum_M LMPLAVPETDADSTLGSLAR--------YDAVELFVARARAGVPEFRLTH
MUL_4753|M.ulcerans_Agy99 LSPLPYPDAASVSSRSSVAR--------YDAVALFVERARTARPGFTLTQ
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
MAB_1988c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 LQLIVTSWSRAGLPVGRLRIGDELAEIDSAALRFDTDEAAALLNDAGGLR
Rv3080c|M.tuberculosis_H37Rv LQLIVTSWSRAGLPVGRLRIGDELAEIDSAALRFDTDEAAALLNDAGGLR
MSMEG_0529|M.smegmatis_MC2_155 LTVVVTSRTQSGLPMSRMRMQGEIVEIDATALRFDVSESGSFLVDLAGLD
MLBr_01753|M.leprae_Br4923 LETVRQYAMKKLEESNEVDLVLARHRDHYMALGALLDTPGDIDHEQLVEQ
Mvan_5928|M.vanbaalenii_PYR-1 LETVRQYAQEKLGESGEADTLRARHRDHYTARAAELDAPSVAGHERRLNQ
Mflv_5210|M.gilvum_PYR-GCK SSGGSVDSAEPALEYGSAQ-------------------------------
MMAR_3547|M.marinum_M ANAAAVARVCARLDGLPLAIELAAARLR--------ALSIEQIADGLADR
MUL_4753|M.ulcerans_Agy99 RNAAAVARICERLDGLPLAIELAAARLR--------AVSVEQIADRLSDR
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
MAB_1988c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 LPRADVQALTTSTDGWAAALRLAALSLRGGGDATQLLRGLSGASDVIHEF
Rv3080c|M.tuberculosis_H37Rv LPRADVQALTTSTDGWAAALRLAALSLRGGGDATQLLRGLSGASDVIHEF
MSMEG_0529|M.smegmatis_MC2_155 LDQTDVEELTEKTDGWVAALQLASLTLRDRDDPVQLIETMTGRHHVISEF
MLBr_01753|M.leprae_Br4923 VETELDNLRSAFAWSRETGDIAGALQLASSLQPIWFGRGHMYEGLAWFDS
Mvan_5928|M.vanbaalenii_PYR-1 TDIEMDNLRAAFAWSRENANTDHSLLLASSLHPLWRARGRLQEGQAWFDA
Mflv_5210|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3547|M.marinum_M YRLLSRGHRGAPTRQQNLVSCVAWSHDLCTPTEQHLWAILSVFAGSFDLP
MUL_4753|M.ulcerans_Agy99 FGLLTRGQRGAPTRQQTLSYCIDWSYDHCTPIQQQLWARLSVFAGSFDLD
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
MAB_1988c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 LSENVLDTLEPELREFLLVASVTERTCGGLASALAGITNGRAMLEEAEHR
Rv3080c|M.tuberculosis_H37Rv LSENVLDTLEPELREFLLVASVTERTCGGLASALAGITNGRAMLEEAEHR
MSMEG_0529|M.smegmatis_MC2_155 LAENVLETLEPSTLDFLLATSIPERICGGLASALTDVPDGQAILEKIEER
MLBr_01753|M.leprae_Br4923 IFEHKNIEHLVAPKEVLARAVANKVMLHAILASSPPDGSDLVTQAQQALT
Mvan_5928|M.vanbaalenii_PYR-1 ALTDYEARPGEADPAVYARALADRAFMDGHVG-----ITDRLDQAQKALA
Mflv_5210|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3547|M.marinum_M AARHVSAGSLLDEQCLDVMCTLVDKSILIRTEHDGQVRFRLLDTLRDYGR
MUL_4753|M.ulcerans_Agy99 AAQYVAPQDMDADDLLDELCALVDKSILIRTEDDGAVRFRLLSTMREYGN
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
MAB_1988c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 GLFLQRTEDDPNWFRFHQMFADFLHRRLERGGSHRVAELHRRASAWFAEN
Rv3080c|M.tuberculosis_H37Rv GLFLQRTEDDPNWFRFHQMFADFLHRRLERGGSHRVAELHRRASAWFAEN
MSMEG_0529|M.smegmatis_MC2_155 DLFLRRIDD--QWFRYHQLFRDFLRHRLSR---ERVCDLHRRACRWYAGQ
MLBr_01753|M.leprae_Br4923 MAREIGDSAVLARALTACGFSSGYDTEVARPYFAEAVELARTQGDKWTLS
Mvan_5928|M.vanbaalenii_PYR-1 MARDIDDPALLVRALTACGGLAAYNADVARPLLAEAVDLARSMGDKWMLA
Mflv_5210|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3547|M.marinum_M THLSAAEHHQLRHRHADYYHRLAAQAYSDWFGPQQIEWLSRLTAETPNLR
MUL_4753|M.ulcerans_Agy99 SRIDAEQYQGLQQSHFDWCERLVTQAHLEWFSRKQVDWIHRLRSELPNIE
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
MAB_1988c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 GYLHEAVDHALAAGDPARAVDLVEQDETNLPEQSKMTTLLAIVQKLPTSM
Rv3080c|M.tuberculosis_H37Rv GYLHEAVDHALAAGDPARAVDLVEQDETNLPEQSKMTTLLAIVQKLPTSM
MSMEG_0529|M.smegmatis_MC2_155 RLVREAVDHALAAGDETEAVRLVENDGLYLVSGGQMATLIGLTAKLPQDI
MLBr_01753|M.leprae_Br4923 QIRLWGVVGFCVSG-DPVALRAAAEAADDLAQEIGDRFVSLQCRLLLSIA
Mvan_5928|M.vanbaalenii_PYR-1 ETLAWQAYAALMGGGDPVAARTAGEEARELADEMGDGFVSRICGWLLGIA
Mflv_5210|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3547|M.marinum_M EALQFCITHEPATALELAANLREIWIPRGMFSEGYRWLDLALTALP-PLP
MUL_4753|M.ulcerans_Agy99 EALQFGLEKAPESVLLMAAKLRNLFVVSGKLQVGRLWVERALSTTTSAQP
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
MAB_1988c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 VVSRARLQLAIAWANILLQRPAPATGALNRFETALGRAELPEATQADLRA
Rv3080c|M.tuberculosis_H37Rv VVSRARLQLAIAWANILLQRPAPATGALNRFETALGRAELPEATQADLRA
MSMEG_0529|M.smegmatis_MC2_155 VRSNPRLQLALAWANIVLHRVPAARDALARVEATMADAGLSEDEIADMRA
MLBr_01753|M.leprae_Br4923 QLWQGDMDGAIVRSGEVVAGAEAAHDTVTRTFGLYVQTRALVHR-DVSAA
Mvan_5928|M.vanbaalenii_PYR-1 HHFQGDLDAALALADGVVSESDVAHDTLNGCCGELVLAHSLAQRGDTDAA
Mflv_5210|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3547|M.marinum_M SPERIRALAHISEFANFRGNLPRATELVAQARQLYESLADR---------
MUL_4753|M.ulcerans_Agy99 SGARIAALAALAMFAVLQTDWPTAQSCVAQAHEHGAAVPDP---------
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
MAB_1988c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 EADVLRAVAEVFADRVERVDDLLAEAMSRPDTLPPRVPGTAGNTAALAAI
Rv3080c|M.tuberculosis_H37Rv EADVLRAVAEVFADRVERVDDLLAEAMSRPDTLPPRVPGTAGNTAALAAI
MSMEG_0529|M.smegmatis_MC2_155 EADVVRAIADLRSDRLSGIDEHVAACLQRRDRMPPFSVATAATVATFAAA
MLBr_01753|M.leprae_Br4923 LVTAGLVVEAAAELSGVYQGIGYAAMVFAALAMGDVAAAVEASEACRPHL
Mvan_5928|M.vanbaalenii_PYR-1 RAAAQVSLNVAVEVSPVHAGLAHAALAVANLAAGDVTAAEAASDSATRSF
Mflv_5210|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3547|M.marinum_M -----------------------------RVIAVLECTDGHMAMINGDFE
MUL_4753|M.ulcerans_Agy99 -----------------------------IAESLLGVARGLGALLQGQVE
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
MAB_1988c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 CRFEFAEVYPLLDWAAPYQEMMG-PFGTVYAQCLRGMAARNRLDIVAALQ
Rv3080c|M.tuberculosis_H37Rv CRFEFAEVYPLLDWAAPYQEMMG-PFGTVYAQCLRGMAARNRLDIVAALQ
MSMEG_0529|M.smegmatis_MC2_155 YRYDLDEVERIQTWAAPYYERSGDAFSIVNGLCFCGIAHHLMLNNAVAEQ
MLBr_01753|M.leprae_Br4923 G----------------------------ADHGLVAIHLELMAAVALARG
Mvan_5928|M.vanbaalenii_PYR-1 G----------------------------PSEVAGIQDPNVAAQIACTRG
Mflv_5210|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3547|M.marinum_M RARDCLRRAA-SATDDLQSKG-CAMLLMGWDSLFWGDVEKASDWFEKALA
MUL_4753|M.ulcerans_Agy99 QVQTDAEQGL-AAG-DFELQV-LGMWLMPLRHLAVGDPEPALRWAEKAHS
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
MAB_1988c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 NFRTAFEVGT-AVG-AHSHAARLAGSLLAELLYETGDLAGAGRLMDESYL
Rv3080c|M.tuberculosis_H37Rv NFRTAFEVGT-AVG-AHSHAARLAGSLLAELLYETGDLAGAGRLMDESYL
MSMEG_0529|M.smegmatis_MC2_155 TLRRALRIAK-RSGGIHSYAGRLASSLLGEILYEKGDLAEAERLLDEGYK
MLBr_01753|M.leprae_Br4923 DVIVARRLADNSVSATTGWHQMAALTTRARIAMAQGEPELARADIHAALA
Mvan_5928|M.vanbaalenii_PYR-1 DLDTARSLVDGAVSITRGVHRASALTTRARIAIAQGDPEQAERNAHDALS
Mflv_5210|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3547|M.marinum_M VSESHGESLQRSYVLVCTGISSWRRGEFERAEQQLQQGIQICRALNDR--
MUL_4753|M.ulcerans_Agy99 VSESRVEVQMRTYSLSALAVSHLMLGDTGSAERSLREGLKLCQVIDDP--
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
MAB_1988c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 LGSEGGAVDYLAARYVIGARVKAAQGDHEGAADRLSTGGDTAVQLGLPRL
Rv3080c|M.tuberculosis_H37Rv LGSEGGAVDYLAARYVIGARVKAAQGDHEGAADRLSTGGDTAVQLGLPRL
MSMEG_0529|M.smegmatis_MC2_155 LGPEGGSVDFKIARYVISARIKALQGDRLGAAQRLDEATRVARSLSLNRL
MLBr_01753|M.leprae_Br4923 CGADIQASLGISDSMELLAELISQGDNHRQAGRLFGAASAQREKTGEVRF
Mvan_5928|M.vanbaalenii_PYR-1 LAAGVGARLEVPDTLECLARVVGDGGSHHEAARLCGAAEAIRGRTGAVRF
Mflv_5210|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3547|M.marinum_M ----------------------------------------WMAAQYFEAL
MUL_4753|M.ulcerans_Agy99 ----------------------------------------WSGASYLEGL
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
MAB_1988c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 AARINNERIRLGIALPAAVAADLLAPRTIPRD--NGIATMTAELDEDSAV
Rv3080c|M.tuberculosis_H37Rv AARINNERIRLGIALPAAVAADLLAPRTIPRD--NGIATMTAELDEDSAV
MSMEG_0529|M.smegmatis_MC2_155 QALAEHERIRLGLPPHPEFGPMPVVSYDARREPVDAMDAIALQFEEASAI
MLBr_01753|M.leprae_Br4923 KVWDAG---------------------------YESAVAVLRGAMGCKDF
Mvan_5928|M.vanbaalenii_PYR-1 RIYDAD---------------------------HETTVTTLRDALGDKAF
Mflv_5210|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3547|M.marinum_M AWCAGSNEDFRRAVVLMAAANVLS--PATGFPLMALFSGLHDECEQRSRA
MUL_4753|M.ulcerans_Agy99 AWTAGANGNLRRAVVLMAAAAALSRSSGAGSTVIALVGSMHQQCERAARE
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
MAB_1988c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 R-LLSAGDSADRDQACQRAGALAAAIDGTRRPLAALQAQILHIETLAATG
Rv3080c|M.tuberculosis_H37Rv R-LLSAGDSADRDQACQRAGALAAAIDGTRRPLAALQAQILHIETLAATG
MSMEG_0529|M.smegmatis_MC2_155 RRLMASDDPAARDLACRWAREWVDRLSALNRPQALLRARRLLGACLAADG
MLBr_01753|M.leprae_Br4923 DSAWAEGAAMPIDDAITYAQRGRGNRKRPTTGWESLTPAEHNVIRLVSEG
Mvan_5928|M.vanbaalenii_PYR-1 EAAWTEGSATSITEAIAYAQRGRGERKRPSSGWASLTPTELDVVGLVSEG
Mflv_5210|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3547|M.marinum_M GLDDAEYQAAWNQGSALSFQQAVMVAMGE---------------------
MUL_4753|M.ulcerans_Agy99 ELSDAVFETARVEGESLSFDDAADVALTEP--------------------
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
MAB_1988c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 RESDARNELAPVATKCAELGLSRLLVDAGLA-------------------
Rv3080c|M.tuberculosis_H37Rv RESDARNELAPVATKCAELGLSRLLVDAGLA-------------------
MSMEG_0529|M.smegmatis_MC2_155 RTAEAKAMVATVAAQCAQLRMLRYLVDGGPQVVATLVELRADQEAGRWSP
MLBr_01753|M.leprae_Br4923 LDTKDIAARLFVSVRTVHTHLTRIYSKLGLTSRVQLVQEAARHN------
Mvan_5928|M.vanbaalenii_PYR-1 LSNKDIAARLFVSPRTVQTHLTHVYTKLCLASRVQLAQEAARHT------
Mflv_5210|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_3547|M.marinum_M ----------------------
MUL_4753|M.ulcerans_Agy99 ----------------------
MAV_2318|M.avium_104 ----------------------
TH_2610|M.thermoresistible__bu ----------------------
MAB_1988c|M.abscessus_ATCC_199 ----------------------
Mb3107c|M.bovis_AF2122/97 ----------------------
Rv3080c|M.tuberculosis_H37Rv ----------------------
MSMEG_0529|M.smegmatis_MC2_155 EWPEVPADFLQDAINSVAPQRY
MLBr_01753|M.leprae_Br4923 ----------------------
Mvan_5928|M.vanbaalenii_PYR-1 ----------------------
Mflv_5210|M.gilvum_PYR-GCK ----------------------