For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VNRGQNRSQNHYTRQLASKTVRRKACGLINPLAEQLNVDGFADAAEVGRGGFGVVYRCRQVDLDRVVAIK VLTIDLDENRPRFEREQRAMAKLTGHPNIVSVLQIGETRDGHPYLVMPYCRRGSVQTEISRLGRLSLADV LQLGVALAAGLESAHRLDILHRDIKPANVLLTDFGEPALTDFGLAHMAGGFRTATGLFTASPAFTASELA RGGEPDRASDVYGVGATLFCALTGHPPFERRKGESVIAQILRVANDPVPDLAEYDVAEDVASVVNRALSR DPAARPTMVELGEAIQSLQAAHGQAVDAMALEGGKRSTSVSSESAWHVSARQTRGNLPAKLAGFVGRQAE LAELGALISTSRLVTLTGVGGVGKTSLAVQAAGEHVSHFHDGVWLVDIGELSDGALLAGLAARMLGIRDQ GARPLTEVLTDALAERDALVIFDGCEHVIDHAAQLIDTLLQGCPQLHILATSRELLGIGGEAVLALSPLP YPDAASVSSRSSVARYDAVALFVERARTARPGFTLTQRNAAAVARICERLDGLPLAIELAAARLRAMSVE QIADRLSDRFGLLTRGQRGAPTRQQTLSYCIDWSYDHCTPIQQQLWARLSVFAGSFDLDAAQYVAPQDMD ADDLLDELCALVDKSILIRTEDDGAVRFRLLSTMREYGNSRIDAEQYQGLQQSHFDWCERLVTQAHLEWF SQKQVDWIHRLRSELPNIEEALQFGLEKAPESVLLMAAKLRNLFVASGKLQVGRLWVERALSTTTSAQPS GARIAALAALAMFAVLQTDWPTAQSCVAQAHEHGAAVPDPIAESLLGVARGLGALLQGQVEQVQTDAEQG LAAGDFELQVLGMWLMSLRHLAVGDPEPALRWAEKAHSVSESRVEVQMRTYSLSALAVSHLMLGDTGSAE RSLREGLKLCQVIDDPWSGASYLEGLAWTAGANGNLRRAVVLMAAAAALSRSSGAGSTVIALVGSMHQQC ERAAREELSDAVFEAARVEGESLSFDEAAAVALTEP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0366 | pknK_3 | - | 100% (1016) | serine/threonine-protein kinase transcriptional regulatory protein PknK_3 |
| M. marinum M | MMAR_0365 | pknK_2 | 0.0 | 59.72% (993) | serine/threonine-protein kinase transcriptional regulatory |
| M. marinum M | MMAR_3547 | - | 0.0 | 50.97% (983) | serine/threonine-protein kinase transcriptional regulatory |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3107c | pknK | 3e-89 | 38.10% (567) | serine/threonine-protein kinase transcriptional regulatory |
| M. gilvum PYR-GCK | Mflv_1389 | - | 4e-28 | 36.33% (245) | protein kinase |
| M. tuberculosis H37Rv | Rv3080c | pknK | 9e-90 | 38.27% (567) | serine/threonine-protein kinase transcriptional regulatory |
| M. leprae Br4923 | MLBr_01753 | - | 8e-64 | 33.54% (480) | putative transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4435 | - | 7e-30 | 35.36% (280) | serine/threonine-protein kinase PknJ |
| M. avium 104 | MAV_2318 | - | 1e-27 | 32.55% (298) | serine-threonine protein kinase |
| M. smegmatis MC2 155 | MSMEG_0529 | - | 6e-80 | 29.27% (967) | serine/threonine-protein kinase PknK |
| M. thermoresistible (build 8) | TH_2631 | - | 4e-25 | 28.49% (344) | PUTATIVE serine/threonine protein kinase |
| M. ulcerans Agy99 | MUL_4753 | pknK_3 | 0.0 | 99.08% (979) | serine/threonine-protein kinase transcriptional regulatory |
| M. vanbaalenii PYR-1 | Mvan_5928 | - | 7e-88 | 35.22% (690) | regulatory protein, LuxR |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0366|M.marinum_M --------------MNRGQNRSQNHYTRQLASKTVRRKACGLINPLAEQL
MUL_4753|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1389|M.gilvum_PYR-GCK ---------------------------------------------MTAEM
TH_2631|M.thermoresistible__bu --------------------------------------------MTTPQH
MAV_2318|M.avium_104 -----------------MAQAESPGSSSGRPGPHRRQAQAESPGSFAGTL
Mb3107c|M.bovis_AF2122/97 -----------------------------MTDVDPHATRRDLVPNIPAEL
Rv3080c|M.tuberculosis_H37Rv -----------------------------MTDVDPHATRRDLVPNIPAEL
MSMEG_0529|M.smegmatis_MC2_155 -----------------------------MVRNDPLPTQRDLPAGIPAEL
MLBr_01753|M.leprae_Br4923 MYSLGEMQKPVPVGADYLASCLVARLRSTDVPTDLHRGCTVTLFLGDVEG
Mvan_5928|M.vanbaalenii_PYR-1 ------MSELVPTG-------------------------TVTLLLADVQG
MAB_4435|M.abscessus_ATCC_1997 ---------------------------MTSSDRSSPGPGGQQPGDLPPGT
MMAR_0366|M.marinum_M NVDGFADAAEVGRGGFGVVYRCRQVDLDRVVAIKVLTIDLDENR---PRF
MUL_4753|M.ulcerans_Agy99 -MDGFADAAEVGRGGFGVVYRCRQVDLDRVVAIKVLTIDLDENR---PRF
Mflv_1389|M.gilvum_PYR-GCK LAGRYELRGLLGRGGMAEVRDGWDTRLDRSVAVKLLYPSQSSDDSVRRRF
TH_2631|M.thermoresistible__bu LSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDPSFYLRF
MAV_2318|M.avium_104 LDGRYLIESKIASGGTSTVYRGVDTRLDRPVAVKVMDPRYAGDEQFLTRF
Mb3107c|M.bovis_AF2122/97 LEAGFDNVEEIGRGGFGVVYRCVQPSLDRAVAVKVLSTDLDRDN--LERF
Rv3080c|M.tuberculosis_H37Rv LEAGFDNVEEIGRGGFGVVYRCVQPSLDRAVAVKVLSTDLDRDN--LERF
MSMEG_0529|M.smegmatis_MC2_155 VAAGFEDPDEIGRGGFGVVYRCVQRALDRTVAVKVLTTDLEPDN--LERF
MLBr_01753|M.leprae_Br4923 LAELSETQPDEAADAIARLDCVVSEAVAAHGGVQQVVQGVRGNFLATFAR
Mvan_5928|M.vanbaalenii_PYR-1 STQLWETQPETMTAAVAQLDRTLTDLVSDHDGVRPVEQGEGDSFVVAFTR
MAB_4435|M.abscessus_ATCC_1997 VVSGYQIERVLGRGGMGTVYLAANPNLQRSEALKILSAQSSRDPEFRARF
. . : : .:: : .
MMAR_0366|M.marinum_M EREQRAMAKLTGHPNIVSV-----LQIGETRDG---HPYLVMPYCRRGSV
MUL_4753|M.ulcerans_Agy99 EREQRAMAKLTGHPNIVSV-----LQIGETRDG---HPYLVMPYCRRGSV
Mflv_1389|M.gilvum_PYR-GCK EDEARSAARLS-HPNIVAI-----HDFGEHDS----APFIVMERLPGRTL
TH_2631|M.thermoresistible__bu RREAQNAAALN-HPAIVAV-----YDTGEAETPTGPLPYIVMEYVDGVTL
MAV_2318|M.avium_104 QREARAVARLK-DPGLVAV-----YDQGLDAR----HPFLVMELIEGGTL
Mb3107c|M.bovis_AF2122/97 LREQRAMGRLSGHPHIVTV-----LQVGVLAGG---RPFIVMPYHAKNSL
Rv3080c|M.tuberculosis_H37Rv LREQRAMGRLSGHPHIVTV-----LQVGVLAGG---RPFIVMPYHAKNSL
MSMEG_0529|M.smegmatis_MC2_155 MREQVAMGKLSGHPNIVNI-----FQVGTIASG---RPYIVMQYHPHGSL
MLBr_01753|M.leprae_Br4923 ASDATACALDLQLAPIVPVRFRIALHTGEVQISNDDVNNVVFMMVQAAGL
Mvan_5928|M.vanbaalenii_PYR-1 ASDAVACALALQRAPLAPIRLRIGVHTGEVRLR-DEGNYVGPTINRTARL
MAB_4435|M.abscessus_ATCC_1997 MREASLAASLD-HPNIVTV-----HNRGETPEG---DLWIAMQYVQG-SD
: . . :. : . * :
MMAR_0366|M.marinum_M QTEISRLGRLSLADVLQLGVALAAGLESAHRLD-ILHRDIKPAN--VLLT
MUL_4753|M.ulcerans_Agy99 QTEISRLGRLSLADILQLGVALAAGLESAHRLD-ILHRDIKPAN--VLLT
Mflv_1389|M.gilvum_PYR-GCK ADVIE-QGPMPAPQVRRVLDEVLAALSVAHAAG-VLHRDIKPAN--ILLT
TH_2631|M.thermoresistible__bu RDIVHTDGPMEPKRAIEVIADACQALNFSHQHG-IIHRDVKPAN--IMIS
MAV_2318|M.avium_104 RELLGERGPMPPYAVAAVLRPVLGGLAAAHRAG-LVHRDVKPEN--VLIS
Mb3107c|M.bovis_AF2122/97 ETLIRRHGPLDWRETLSIGVKLAGALEAAHRVG-TLHRDVKPGN--ILLT
Rv3080c|M.tuberculosis_H37Rv ETLIRRHGPLDWRETLSIGVKLAGALEAAHRVG-TLHRDVKPGN--ILLT
MSMEG_0529|M.smegmatis_MC2_155 SAKIQAAGPLGWRGALRIGVKMAGALETAHQRD-TLHRDVKPAN--ILLT
MLBr_01753|M.leprae_Br4923 LDLACGGQTVLSSITGDLVVDGLPADTWLVDLGSHLLRDLARPVRVMQLC
Mvan_5928|M.vanbaalenii_PYR-1 RELAHGGQTVLSGTTSDLVADLLPDGGWLSDLGTHRLRDLPRPERVVQLC
MAB_4435|M.abscessus_ATCC_1997 AHSESASGRMSLTRAVHIISEVAKALDYLHARG-LVHRDVKPAN--ILLS
: : . **: : :
MMAR_0366|M.marinum_M DFG-EPALTDFGLAHMAG--GFRTATGLFTASPAFTASELARGGEPDRAS
MUL_4753|M.ulcerans_Agy99 DFG-EPALTDFGLAHMAG--GFRTATGLFTASPAFTASELARGGEPDRAS
Mflv_1389|M.gilvum_PYR-GCK TAGDSVKVADFGIAKSAG--AAHTATGQIVGTLCYLSPERVMGAPASVAD
TH_2631|M.thermoresistible__bu KTG-AVKVMDFGIARAIADSNSVTQTAAVIGTAQYLSPEQARGETVDARS
MAV_2318|M.avium_104 DDG-EVKIADFGLVRAVA-AAGITSASVILGTAAYLSPEQVRDGAATPRS
Mb3107c|M.bovis_AF2122/97 DYG-EPQLTDFGIARIAG--GFETATGVIAGSPAFTAPEVLEGASPTPAS
Rv3080c|M.tuberculosis_H37Rv DYG-EPQLTDFGIARIAG--GFETATGVIAGSPAFTAPEVLEGASPTPAS
MSMEG_0529|M.smegmatis_MC2_155 EYG-EPQLTDFGIARIAG--GFETAEGAIMGSPAYTAPEVLLGESPTVAS
MLBr_01753|M.leprae_Br4923 HRNLRRNLHELGIRTVPGGPSLPVPLTTFVGRAAQIKELQELLTEKRLLT
Mvan_5928|M.vanbaalenii_PYR-1 HADLSNEFPPLRAREEIGVQRLPAQLTSFVGRVDDMAQVRGLMDANRLVT
MAB_4435|M.abscessus_ATCC_1997 AGDRRIMLGDFGLTRALDDSNSVTSAGNVTATIAYAAPEILSGTAVDGRA
. . : . . .
MMAR_0366|M.marinum_M DVYGVGATLFCALTGHPPFERRKGESVIAQILRVANDPVPDLAEYDVA--
MUL_4753|M.ulcerans_Agy99 DVYGVGATLFCALTGHPPFERRKGESVIAQILRVANDPVPDLAEYDVA--
Mflv_1389|M.gilvum_PYR-GCK DLYAVGVMGYEALLGRRAFPQDNPAALARAIIDVP-PPPLRALSVTAD--
TH_2631|M.thermoresistible__bu DVYSLGCVLYEILTGEPPFVGDSPVAVAYQHVRED-PVPPSRRNPAVS--
MAV_2318|M.avium_104 DVYAAGILAYELLTGRTPFTGDSTLAIAYRRLDAD-VPPPSAAIDGVP--
Mb3107c|M.bovis_AF2122/97 DVYSLGATLFCVLTGHAAYERRSGERVIAQFLRITSQPIPDLRKQGLP--
Rv3080c|M.tuberculosis_H37Rv DVYSLGATLFCALTGHAAYERRSGERVIAQFLRITSQPIPDLRKQGLP--
MSMEG_0529|M.smegmatis_MC2_155 DVYSLASTVFTASTGHAVFERGKGEQMVAQFLRITRHPAPNLRDADLP--
MLBr_01753|M.leprae_Br4923 -LVGPGGVGKTRLALQVVARVADEFSGELSYFDLAPDTDHDIFPITVL--
Mvan_5928|M.vanbaalenii_PYR-1 -LTGAGGVGKTRLATQVAVAVVEGYPGGVWYVDLAPITDPALVAITVARA
MAB_4435|M.abscessus_ATCC_1997 DVYALGCTLFRMLTGQPPFGSGNSLPAIINAHLSAPPPRISQLA-PVP--
: . . . .
MMAR_0366|M.marinum_M ------------EDVASVVNRALSRDPAARP-TMVELGEAIQSLQAAHGQ
MUL_4753|M.ulcerans_Agy99 ------------EDVASVVNRALSRDPAARP-TMVELGEAIQSLQAAHGQ
Mflv_1389|M.gilvum_PYR-GCK ------------PALVAVIDRAMSRDPRLRFGSAPQMRAALAGDPLALNN
TH_2631|M.thermoresistible__bu ------------PELDAVVLKALAKNPDNRYQTAAEMRADLVRVHSGEQP
MAV_2318|M.avium_104 ------------AQFDDFVQRATARDPADRYADAVEMGADLDAIADELAL
Mb3107c|M.bovis_AF2122/97 ------------ADVAAAIERAMARHPADRPATAADVGEELRDVQRRNGV
Rv3080c|M.tuberculosis_H37Rv ------------ADVAAAIERAMARHPADRPATAADVGEELRDVQRRNGV
MSMEG_0529|M.smegmatis_MC2_155 ------------ADLSAAIEQAMSRTISDRPESAQAFGEQLRELQRRHGL
MLBr_01753|M.leprae_Br4923 ------------DNLRRCIGDRRMLMVLDNCEYLLDVCANVMTTLLGACP
Mvan_5928|M.vanbaalenii_PYR-1 LGLPDQPGRSTVDTIVRFIADRRMLVVLDNCEHLLDACATLIDALLGACP
MAB_4435|M.abscessus_ATCC_1997 ------------ESWDALIAKAMAKTPADRYQSAGELAMAAQQILTDPAQ
: .
MMAR_0366|M.marinum_M AVDAMALEGGKRSTSVS---------------------------------
MUL_4753|M.ulcerans_Agy99 AVDAMALEGGKRSTSVS---------------------------------
Mflv_1389|M.gilvum_PYR-GCK APPPAPPPRAG---------------------------------------
TH_2631|M.thermoresistible__bu EAPKVLTDAER---------------------------------------
MAV_2318|M.avium_104 PGFRVPAPRNS---------------------------------------
Mb3107c|M.bovis_AF2122/97 SVDEMPLPVELGVERRRSPEAHAAHRHTGGGTPTVPTPPTPATKYRPSVP
Rv3080c|M.tuberculosis_H37Rv SVDEMPLPVELGVERRRSPEAHAAHRHTGGGTPTVPTPPTPATKYRPSVP
MSMEG_0529|M.smegmatis_MC2_155 PVDDMPIPIAPPTDR---PSSIASPTPSSGYPVRTLTPPAPATRFQMPSS
MLBr_01753|M.leprae_Br4923 SLTILATSREPIGVAG----------------------------------
Mvan_5928|M.vanbaalenii_PYR-1 ALAMLATSREPIAVAG----------------------------------
MAB_4435|M.abscessus_ATCC_1997 HRQTVTQPVPA---------------------------------------
MMAR_0366|M.marinum_M -------------------------------SESAWHVSARQTRGNLPAK
MUL_4753|M.ulcerans_Agy99 -------------------------------SESAWHVSARQTRGNLPAK
Mflv_1389|M.gilvum_PYR-GCK --------------------------------TRVLAQPLPPSAGFTSAP
TH_2631|M.thermoresistible__bu --------------------------------TSLLASGPAHDRTQPTDA
MAV_2318|M.avium_104 --------------------------------ALHRSAALHREAGRRAPG
Mb3107c|M.bovis_AF2122/97 TGSLVTRSRLTDILRAGGRRRLILIHAPSGFGKSTLAAQWREELSRDGAA
Rv3080c|M.tuberculosis_H37Rv TGSLVTRSRLTDILRAGGRRRLILIHAPSGFGKSTLAAQWREELSRDGAA
MSMEG_0529|M.smegmatis_MC2_155 AKRLVERARLIDVLRAQRDKKLTVIHGPTGFGKSTLAVQWAKQLAADGVA
MLBr_01753|M.leprae_Br4923 ---------------------EVIWRVSMLSPADEAVELFTERAALVQPG
Mvan_5928|M.vanbaalenii_PYR-1 ---------------------EQTWRVPPLALDDDAIELFTDRARRARPD
MAB_4435|M.abscessus_ATCC_1997 ---------------------------------TTPAPIAAPEPVHAMAP
MMAR_0366|M.marinum_M LAGFVGRQAELAELGALISTSRLVTLTGVGGVGKTSLAVQAAGEHVS---
MUL_4753|M.ulcerans_Agy99 LAGFVGRQAELAELGALISTSRPVTLTGVGGVGKTSLAVQAAGEHVS---
Mflv_1389|M.gilvum_PYR-GCK VGYPTAAPPPPTR---ARMYLMAVAAVLAFTVAALALALDPFSSPP----
TH_2631|M.thermoresistible__bu VIDPVIPRYTGSDRGGSVGRWVAAVAVLAVLTVVVTVAINMIGGNPR---
MAV_2318|M.avium_104 AEPPARHP---------TRHLTRGPEEWPQPEPPAHVGAEPDDDED----
Mb3107c|M.bovis_AF2122/97 VAWLTIDNDDNNEVWFLSHLLESIRRVRPTLAESLGHVLEEHGDDAGRYV
Rv3080c|M.tuberculosis_H37Rv VAWLTIDNDDNNEVWFLSHLLESIRRVRPTLAESLGHVLEEHGDDAGRYV
MSMEG_0529|M.smegmatis_MC2_155 VAWLTVDDDDNNVVWFLSHVIEAIRSVMPALASDLGDVLEEHGDDAERYV
MLBr_01753|M.leprae_Br4923 FSVTDGNRQIVTEICQRLDGMPLAIELAAARIRTLSLTEIADGLDDR---
Mvan_5928|M.vanbaalenii_PYR-1 FIISADDAAAVSEICHRLDGMPLAIELAAARVRALSLTEIVDGLHDR---
MAB_4435|M.abscessus_ATCC_1997 LAMADTGQSMLKHKRIAAIIGVMVLVVASSVVAVLIWPRADEGTDPR---
.
MMAR_0366|M.marinum_M ----------------------HFHDGVWLVDIGELSDGALLAGLAARML
MUL_4753|M.ulcerans_Agy99 ----------------------HFHDGVWLVDIGELSDGALLAGLAARML
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------PMQTVGTSTTAP
TH_2631|M.thermoresistible__bu ---------------------NVQVPDVSGQASADAIAALQNRGFKTRTQ
MAV_2318|M.avium_104 -------------------------------------------DYEYQSV
Mb3107c|M.bovis_AF2122/97 LTSLIDEIHENDDRIAVVIDDWHRVSDSRTQAALGFLLDNGCHHLQLIVT
Rv3080c|M.tuberculosis_H37Rv LTSLIDEIHENDDRIAVVIDDWHRVSDSRTQAALGFLLDNGCHHLQLIVT
MSMEG_0529|M.smegmatis_MC2_155 LTSLINDIHSSGRRMTLVIDDWHRVTDPATIAALRYLLDNVASGLTVVVT
MLBr_01753|M.leprae_Br4923 ---------------------FRLLTGGARTAVRRQQTLRASMDWSYALL
Mvan_5928|M.vanbaalenii_PYR-1 ---------------------FRLLTGGSRTAVRRQQTLRASVDWSHGLL
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------TKASPSAAQVAP
MMAR_0366|M.marinum_M GIRDQGARPLTEVLTDALAERDALVIFDGCEHVIDHAAQLIDTLLQGCPQ
MUL_4753|M.ulcerans_Agy99 GIRDQGARPLTEVLTDALAERDALVIFDGCEHVIDHAAQLIDTLLQGCPQ
Mflv_1389|M.gilvum_PYR-GCK PPPTSVPPPTSAAPLPPPIVP-----------------------------
TH_2631|M.thermoresistible__bu QQPDNSVPPDRVISTDPPADTSVSAGDEITVNVSTGPQQREIPDVSSLTY
MAV_2318|M.avium_104 TGEFAGIPISEFVWARQHNRR-----------------------------
Mb3107c|M.bovis_AF2122/97 SWSRAGLPVGRLRIGDELAEIDSAALRFDTDEAAALLNDAGGLRLPRADV
Rv3080c|M.tuberculosis_H37Rv SWSRAGLPVGRLRIGDELAEIDSAALRFDTDEAAALLNDAGGLRLPRADV
MSMEG_0529|M.smegmatis_MC2_155 SRTQSGLPMSRMRMQGEIVEIDATALRFDVSESGSFLVDLAGLDLDQTDV
MLBr_01753|M.leprae_Br4923 TESERALFRRLSAISGTFDLKVAYAVGHDDLEEPDQVFDRLTMLIDKSLV
Mvan_5928|M.vanbaalenii_PYR-1 TDPERVLFRRLAVFAGGFDLDGAQAITVDGEVHRYEVVDLLTLLVDKSLL
MAB_4435|M.abscessus_ATCC_1997 GASLAGQPNTVLDTLLPGQFDYPEG-------------------------
MMAR_0366|M.marinum_M LHILATSRELLGIGG----------------EAVLALSPLPYPDAASVSS
MUL_4753|M.ulcerans_Agy99 LHILATSRELLGIGG----------------EAVLALSPLPYPDAASVSS
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
TH_2631|M.thermoresistible__bu AEAVRRLS------------------------------AAGFEKFRQSES
MAV_2318|M.avium_104 --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 QALTTSTDGWAAALRLAALSLRGGGDATQLLRGLSGASDVIHEFLSENVL
Rv3080c|M.tuberculosis_H37Rv QALTTSTDGWAAALRLAALSLRGGGDATQLLRGLSGASDVIHEFLSENVL
MSMEG_0529|M.smegmatis_MC2_155 EELTEKTDGWVAALQLASLTLRDRDDPVQLIETMTGRHHVISEFLAENVL
MLBr_01753|M.leprae_Br4923 IVEGRQGGSRYRLLETVRQYAMKKLEESNEVDLVLARHRDHYMALGALLD
Mvan_5928|M.vanbaalenii_PYR-1 IAENTAGRTRYRLLETVRQYAQEKLGESGEADTLRARHRDHYTARAAELD
MAB_4435|M.abscessus_ATCC_1997 ----------------------------------------------WEKN
MMAR_0366|M.marinum_M RSSVARYDAVALFVERART-ARPGFTLTQRNAAAVARICERLDGLPLAIE
MUL_4753|M.ulcerans_Agy99 RSSVARYDAVALFVERART-ARPGFTLTQRNAAAVARICERLDGLPLAIE
Mflv_1389|M.gilvum_PYR-GCK ---------VTQAPPPDNG-PKKGPDKKGEKGNNGRGNGNKPD-------
TH_2631|M.thermoresistible__bu PSTPELRGKVVATNPPANQ-TAAITNEITVVVGTGPATREVPDITGQTVE
MAV_2318|M.avium_104 ----------MVLVWLALV-LAVTGMVATAAWTIGRNLNGLF--------
Mb3107c|M.bovis_AF2122/97 DTLEPELREFLLVASVTER-TCGGLASALAGITNGRAMLEEAEHRGLFLQ
Rv3080c|M.tuberculosis_H37Rv DTLEPELREFLLVASVTER-TCGGLASALAGITNGRAMLEEAEHRGLFLQ
MSMEG_0529|M.smegmatis_MC2_155 ETLEPSTLDFLLATSIPER-ICGGLASALTDVPDGQAILEKIEERDLFLR
MLBr_01753|M.leprae_Br4923 TPGDIDHEQLVEQVETELDNLRSAFAWSRETGDIAGALQLASSLQPIWFG
Mvan_5928|M.vanbaalenii_PYR-1 APSVAGHERRLNQTDIEMDNLRAAFAWSRENANTDHSLLLASSLHPLWRA
MAB_4435|M.abscessus_ATCC_1997 PSPTFRSGEFNPAVPPGSATNIGGTPVGCNTIDPAWALRAKGRETSTLYL
MMAR_0366|M.marinum_M LAAARLRAMSVEQIADRLSDRFGLLTRGQRGAPTRQQTLSYCIDWSYDHC
MUL_4753|M.ulcerans_Agy99 LAAARLRAVSVEQIADRLSDRFGLLTRGQRGAPTRQQTLSYCIDWSYDHC
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
TH_2631|M.thermoresistible__bu LAERNLSVYGFTKFTQSAVDST--APAG----------------------
MAV_2318|M.avium_104 --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 RTEDDPNWFRFHQMFADFLHRR--LERGGSHRVAELHRRASAWFAENGYL
Rv3080c|M.tuberculosis_H37Rv RTEDDPNWFRFHQMFADFLHRR--LERGGSHRVAELHRRASAWFAENGYL
MSMEG_0529|M.smegmatis_MC2_155 RIDD--QWFRYHQLFRDFLRHR--LSR---ERVCDLHRRACRWYAGQRLV
MLBr_01753|M.leprae_Br4923 RGHMYEGLAWFDSIFEHKNIEHLVAPKEVLARAVANKVMLHAILASSPPD
Mvan_5928|M.vanbaalenii_PYR-1 RGRLQEGQAWFDAALTDYEARPGEADPAVYARALADRAFMDGHVG-----
MAB_4435|M.abscessus_ATCC_1997 RDRKKPEREILIRVVP----------------------------------
MMAR_0366|M.marinum_M TPIQQQLWARLSVFAGSFDLDAAQYVAPQDMDADDLLDELCALVDKSILI
MUL_4753|M.ulcerans_Agy99 TPIQQQLWARLSVFAGSFDLDAAQYVAPQDMDADDLLDELCALVDKSILI
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
TH_2631|M.thermoresistible__bu --QVVGTNPPAGTTVSLDSVIELEVSKGNQFVMPDLIGMFWTDAEPRLR-
MAV_2318|M.avium_104 --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 HEAVDHALAAGDPARAVDLVEQDETNLPEQSKMTTLLAIVQKLPTSMVVS
Rv3080c|M.tuberculosis_H37Rv HEAVDHALAAGDPARAVDLVEQDETNLPEQSKMTTLLAIVQKLPTSMVVS
MSMEG_0529|M.smegmatis_MC2_155 REAVDHALAAGDETEAVRLVENDGLYLVSGGQMATLIGLTAKLPQDIVRS
MLBr_01753|M.leprae_Br4923 GSDLVTQAQQALTMAREIGDSAVLARALTACGFSSGYDTEVARPYFAEAV
Mvan_5928|M.vanbaalenii_PYR-1 ITDRLDQAQKALAMARDIDDPALLVRALTACGGLAAYNADVARPLLAEAV
MAB_4435|M.abscessus_ATCC_1997 AADALSTDGASDALKRCDAVAYIIPGSSTTWRCSFEFDEPNPVQNGQKEL
MMAR_0366|M.marinum_M RTEDDGAVRFRLLSTMREYGNSRIDAEQYQGLQQSHFDWCERLVTQAHLE
MUL_4753|M.ulcerans_Agy99 RTEDDGAVRFRLLSTMREYGNSRIDAEQYQGLQQSHFDWCERLVTQAHLE
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
TH_2631|M.thermoresistible__bu ------ALGWTGVLDKGADIPNSGQRANAVVRQNPSPGAGVNYDARITLN
MAV_2318|M.avium_104 --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 RARLQLAIAWANILLQRPAPATGALNRFETALGRAELPEATQADLRAEAD
Rv3080c|M.tuberculosis_H37Rv RARLQLAIAWANILLQRPAPATGALNRFETALGRAELPEATQADLRAEAD
MSMEG_0529|M.smegmatis_MC2_155 NPRLQLALAWANIVLHRVPAARDALARVEATMADAGLSEDEIADMRAEAD
MLBr_01753|M.leprae_Br4923 ELARTQGDKWTLSQIRLWGVVGFCVSG-DPVALRAAAEAADDLAQEIGDR
Mvan_5928|M.vanbaalenii_PYR-1 DLARSMGDKWMLAETLAWQAYAALMGGGDPVAARTAGEEARELADEMGDG
MAB_4435|M.abscessus_ATCC_1997 TTTESCYMFPSGANSIRQHVSFNVVRGLLVYILASGASNRNDAAGSLSAT
MMAR_0366|M.marinum_M WFSQKQVDWIHRLRSELPNIEEALQFGLEKAPESVLLMAAKLRNLFVASG
MUL_4753|M.ulcerans_Agy99 WFSRKQVDWIHRLRSELPNIEEALQFGLEKAPESVLLMAAKLRNLFVVSG
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
TH_2631|M.thermoresistible__bu FAS-----------------------------------------------
MAV_2318|M.avium_104 --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 VLRAVAEVFADRVERVDDLLAEAMSRPDTLPPRVPGTAGNTAALAAICRF
Rv3080c|M.tuberculosis_H37Rv VLRAVAEVFADRVERVDDLLAEAMSRPDTLPPRVPGTAGNTAALAAICRF
MSMEG_0529|M.smegmatis_MC2_155 VVRAIADLRSDRLSGIDEHVAACLQRRDRMPPFSVATAATVATFAAAYRY
MLBr_01753|M.leprae_Br4923 FVSLQCRLLLSIAQLWQGDMDGAIVRSGEVVAGAEAAHDTVTRTFGLYVQ
Mvan_5928|M.vanbaalenii_PYR-1 FVSRICGWLLGIAHHFQGDLDAALALADGVVSESDVAHDTLNGCCGELVL
MAB_4435|M.abscessus_ATCC_1997 ALSFATTMKILRYGR-----------------------------------
MMAR_0366|M.marinum_M KLQVGRLWVERALSTTTSAQPSGARIAALAALAMFAVLQTDWPTAQS---
MUL_4753|M.ulcerans_Agy99 KLQVGRLWVERALSTTTSAQPSGARIAALAALAMFAVLQTDWPTAQS---
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
TH_2631|M.thermoresistible__bu --------------------------------------------------
MAV_2318|M.avium_104 --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 EFAEVYPLLDWAAPYQEMMG-PFGTVYAQCLRGMAARNRLDIVAALQNFR
Rv3080c|M.tuberculosis_H37Rv EFAEVYPLLDWAAPYQEMMG-PFGTVYAQCLRGMAARNRLDIVAALQNFR
MSMEG_0529|M.smegmatis_MC2_155 DLDEVERIQTWAAPYYERSGDAFSIVNGLCFCGIAHHLMLNNAVAEQTLR
MLBr_01753|M.leprae_Br4923 TRALVHR-DVSAALVTAGLVVEAAAELSGVYQGIGYAAMVFAALAMGDVA
Mvan_5928|M.vanbaalenii_PYR-1 AHSLAQRGDTDAARAAAQVSLNVAVEVSPVHAGLAHAALAVANLAAGDVT
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_0366|M.marinum_M -------CVAQAHEHGAAVPDPIAESLLGVARGLGALLQGQVEQVQTDAE
MUL_4753|M.ulcerans_Agy99 -------CVAQAHEHGAAVPDPIAESLLGVARGLGALLQGQVEQVQTDAE
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
TH_2631|M.thermoresistible__bu --------------------------------------------------
MAV_2318|M.avium_104 --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 TAFEVGTAVG-AHSHAARLAGSLLAELLYETGDLAGAGRLMDESYLLGSE
Rv3080c|M.tuberculosis_H37Rv TAFEVGTAVG-AHSHAARLAGSLLAELLYETGDLAGAGRLMDESYLLGSE
MSMEG_0529|M.smegmatis_MC2_155 RALRIAKRSGGIHSYAGRLASSLLGEILYEKGDLAEAERLLDEGYKLGPE
MLBr_01753|M.leprae_Br4923 AAVEASEACRPHLGADHGLVAIHLELMAAVALARGDVIVARRLADNSVSA
Mvan_5928|M.vanbaalenii_PYR-1 AAEAASDSATRSFGPSEVAGIQDPNVAAQIACTRGDLDTARSLVDGAVSI
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_0366|M.marinum_M QGLAAGDFELQVLGMWLMSLRHLAVGDPEPALRWAEKAHSVSESRVEVQM
MUL_4753|M.ulcerans_Agy99 QGLAAGDFELQVLGMWLMPLRHLAVGDPEPALRWAEKAHSVSESRVEVQM
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
TH_2631|M.thermoresistible__bu --------------------------------------------------
MAV_2318|M.avium_104 --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 GGAVDYLAARYVIGARVKAAQGDHEGAADRLSTGGDTAVQLGLPRLAARI
Rv3080c|M.tuberculosis_H37Rv GGAVDYLAARYVIGARVKAAQGDHEGAADRLSTGGDTAVQLGLPRLAARI
MSMEG_0529|M.smegmatis_MC2_155 GGSVDFKIARYVISARIKALQGDRLGAAQRLDEATRVARSLSLNRLQALA
MLBr_01753|M.leprae_Br4923 TTGWHQMAALTTRARIAMAQGEPELARADIHAALACGADIQASLGISDSM
Mvan_5928|M.vanbaalenii_PYR-1 TRGVHRASALTTRARIAIAQGDPEQAERNAHDALSLAAGVGARLEVPDTL
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_0366|M.marinum_M RTYSLSALAVSHLMLG----DTGSAERSLREGLKLCQVIDDPWSGASYLE
MUL_4753|M.ulcerans_Agy99 RTYSLSALAVSHLMLG----DTGSAERSLREGLKLCQVIDDPWSGASYLE
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
TH_2631|M.thermoresistible__bu --------------------------------------------------
MAV_2318|M.avium_104 --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 NNERIRLGIALPAAVAADLLAPRTIPRD--NGIATMTAELDEDSAVR-LL
Rv3080c|M.tuberculosis_H37Rv NNERIRLGIALPAAVAADLLAPRTIPRD--NGIATMTAELDEDSAVR-LL
MSMEG_0529|M.smegmatis_MC2_155 EHERIRLGLPPHPEFGPMPVVSYDARREPVDAMDAIALQFEEASAIRRLM
MLBr_01753|M.leprae_Br4923 ELLAELISQGDNHRQAGRLFGAASAQREKTGEVRFKVWDAGYESAVAVLR
Mvan_5928|M.vanbaalenii_PYR-1 ECLARVVGDGGSHHEAARLCGAAEAIRGRTGAVRFRIYDADHETTVTTLR
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_0366|M.marinum_M GLAWTAGANGNLRRAVVLMAAAAALSRSSGAGSTVIALVGSMHQQCERAA
MUL_4753|M.ulcerans_Agy99 GLAWTAGANGNLRRAVVLMAAAAALSRSSGAGSTVIALVGSMHQQCERAA
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
TH_2631|M.thermoresistible__bu --------------------------------------------------
MAV_2318|M.avium_104 --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 SAGDSADRDQACQRAGALAAAIDGTRRPLAALQAQILHIETLAATGRESD
Rv3080c|M.tuberculosis_H37Rv SAGDSADRDQACQRAGALAAAIDGTRRPLAALQAQILHIETLAATGRESD
MSMEG_0529|M.smegmatis_MC2_155 ASDDPAARDLACRWAREWVDRLSALNRPQALLRARRLLGACLAADGRTAE
MLBr_01753|M.leprae_Br4923 GAMGCKDFDSAWAEGAAMPIDDAITYAQRGRGNRKRPTTGWESLTPAEHN
Mvan_5928|M.vanbaalenii_PYR-1 DALGDKAFEAAWTEGSATSITEAIAYAQRGRGERKRPSSGWASLTPTELD
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_0366|M.marinum_M REELSDAVFEAARVEGESLSFDEAAAVALTEP------------------
MUL_4753|M.ulcerans_Agy99 REELSDAVFETARVEGESLSFDDAADVALTEP------------------
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
TH_2631|M.thermoresistible__bu --------------------------------------------------
MAV_2318|M.avium_104 --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 ARNELAPVATKCAELGLSRLLVDAGLA-----------------------
Rv3080c|M.tuberculosis_H37Rv ARNELAPVATKCAELGLSRLLVDAGLA-----------------------
MSMEG_0529|M.smegmatis_MC2_155 AKAMVATVAAQCAQLRMLRYLVDGGPQVVATLVELRADQEAGRWSPEWPE
MLBr_01753|M.leprae_Br4923 VIRLVSEGLDTKDIAARLFVSVRTVHTHLTRIYSKLGLTSRVQLVQEAAR
Mvan_5928|M.vanbaalenii_PYR-1 VVGLVSEGLSNKDIAARLFVSPRTVQTHLTHVYTKLCLASRVQLAQEAAR
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_0366|M.marinum_M ------------------
MUL_4753|M.ulcerans_Agy99 ------------------
Mflv_1389|M.gilvum_PYR-GCK ------------------
TH_2631|M.thermoresistible__bu ------------------
MAV_2318|M.avium_104 ------------------
Mb3107c|M.bovis_AF2122/97 ------------------
Rv3080c|M.tuberculosis_H37Rv ------------------
MSMEG_0529|M.smegmatis_MC2_155 VPADFLQDAINSVAPQRY
MLBr_01753|M.leprae_Br4923 HN----------------
Mvan_5928|M.vanbaalenii_PYR-1 HT----------------
MAB_4435|M.abscessus_ATCC_1997 ------------------