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DGFADAAEVGRGGFGVVYRCRQVDLDRVVAIKVLTIDLDENRPRFEREQRAMAKLTGHPNIVSVLQIGET RDGHPYLVMPYCRRGSVQTEISRLGRLSLADILQLGVALAAGLESAHRLDILHRDIKPANVLLTDFGEPA LTDFGLAHMAGGFRTATGLFTASPAFTASELARGGEPDRASDVYGVGATLFCALTGHPPFERRKGESVIA QILRVANDPVPDLAEYDVAEDVASVVNRALSRDPAARPTMVELGEAIQSLQAAHGQAVDAMALEGGKRST SVSSESAWHVSARQTRGNLPAKLAGFVGRQAELAELGALISTSRPVTLTGVGGVGKTSLAVQAAGEHVSH FHDGVWLVDIGELSDGALLAGLAARMLGIRDQGARPLTEVLTDALAERDALVIFDGCEHVIDHAAQLIDT LLQGCPQLHILATSRELLGIGGEAVLALSPLPYPDAASVSSRSSVARYDAVALFVERARTARPGFTLTQR NAAAVARICERLDGLPLAIELAAARLRAVSVEQIADRLSDRFGLLTRGQRGAPTRQQTLSYCIDWSYDHC TPIQQQLWARLSVFAGSFDLDAAQYVAPQDMDADDLLDELCALVDKSILIRTEDDGAVRFRLLSTMREYG NSRIDAEQYQGLQQSHFDWCERLVTQAHLEWFSRKQVDWIHRLRSELPNIEEALQFGLEKAPESVLLMAA KLRNLFVVSGKLQVGRLWVERALSTTTSAQPSGARIAALAALAMFAVLQTDWPTAQSCVAQAHEHGAAVP DPIAESLLGVARGLGALLQGQVEQVQTDAEQGLAAGDFELQVLGMWLMPLRHLAVGDPEPALRWAEKAHS VSESRVEVQMRTYSLSALAVSHLMLGDTGSAERSLREGLKLCQVIDDPWSGASYLEGLAWTAGANGNLRR AVVLMAAAAALSRSSGAGSTVIALVGSMHQQCERAAREELSDAVFETARVEGESLSFDDAADVALTEP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4753 | pknK_3 | - | 100% (979) | serine/threonine-protein kinase transcriptional regulatory protein PknK_3 |
| M. ulcerans Agy99 | MUL_4754 | pknK_2 | 0.0 | 59.27% (982) | serine/threonine-protein kinase transcriptional regulatory |
| M. ulcerans Agy99 | MUL_2743 | - | 1e-65 | 40.10% (394) | LuxR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3107c | pknK | 4e-88 | 38.38% (555) | serine/threonine-protein kinase transcriptional regulatory |
| M. gilvum PYR-GCK | Mflv_1389 | - | 6e-28 | 35.92% (245) | protein kinase |
| M. tuberculosis H37Rv | Rv3080c | pknK | 1e-88 | 38.56% (555) | serine/threonine-protein kinase transcriptional regulatory |
| M. leprae Br4923 | MLBr_01753 | - | 1e-62 | 33.33% (480) | putative transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4435 | - | 9e-30 | 35.36% (280) | serine/threonine-protein kinase PknJ |
| M. marinum M | MMAR_0366 | pknK_3 | 0.0 | 99.08% (979) | serine/threonine-protein kinase transcriptional regulatory |
| M. avium 104 | MAV_2318 | - | 1e-27 | 32.21% (298) | serine-threonine protein kinase |
| M. smegmatis MC2 155 | MSMEG_0529 | - | 2e-78 | 29.21% (962) | serine/threonine-protein kinase PknK |
| M. thermoresistible (build 8) | TH_2610 | - | 4e-25 | 31.23% (333) | PUTATIVE serine/threonine protein kinase |
| M. vanbaalenii PYR-1 | Mvan_5928 | - | 1e-86 | 35.07% (690) | regulatory protein, LuxR |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_4753|M.ulcerans_Agy99 ----------------------------------------MDGFADAAEV
MMAR_0366|M.marinum_M ---MNRGQNRSQNHYTRQLASKTVRRKACGLINPLAEQLNVDGFADAAEV
MAV_2318|M.avium_104 ------MAQAESPGSSSGRPGPHRRQAQAESPGSFAGTLLDGRYLIESKI
TH_2610|M.thermoresistible__bu ---------VETYQQSD----------------PFAGTVLDGRYRIDTLI
Mflv_1389|M.gilvum_PYR-GCK ----------------------------------MTAEMLAGRYELRGLL
Mb3107c|M.bovis_AF2122/97 ------MTDVDPHATRR------------DLVPNIPAELLEAGFDNVEEI
Rv3080c|M.tuberculosis_H37Rv ------MTDVDPHATRR------------DLVPNIPAELLEAGFDNVEEI
MSMEG_0529|M.smegmatis_MC2_155 ------MVRNDPLPTQR------------DLPAGIPAELVAAGFEDPDEI
MLBr_01753|M.leprae_Br4923 MYSLGEMQKPVPVGADYLASCLVARLRSTDVPTDLHRGCTVTLFLGDVEG
Mvan_5928|M.vanbaalenii_PYR-1 ------MSELVPTG-------------------------TVTLLLADVQG
MAB_4435|M.abscessus_ATCC_1997 ------MTSSDRSSPGPG----------GQQPGDLPPGTVVSGYQIERVL
MUL_4753|M.ulcerans_Agy99 GRGGFGVVYRCRQVDLDRVVAIKVLTIDLDENR---PRFEREQRAMAKLT
MMAR_0366|M.marinum_M GRGGFGVVYRCRQVDLDRVVAIKVLTIDLDENR---PRFEREQRAMAKLT
MAV_2318|M.avium_104 ASGGTSTVYRGVDTRLDRPVAVKVMDPRYAGDEQFLTRFQREARAVARLK
TH_2610|M.thermoresistible__bu ATGGMSAVYRGLDLRLDRPVAVKVMDSRYAGDQQFLTRFQREARAAARLK
Mflv_1389|M.gilvum_PYR-GCK GRGGMAEVRDGWDTRLDRSVAVKLLYPSQSSDDSVRRRFEDEARSAARLS
Mb3107c|M.bovis_AF2122/97 GRGGFGVVYRCVQPSLDRAVAVKVLSTDLDRDN--LERFLREQRAMGRLS
Rv3080c|M.tuberculosis_H37Rv GRGGFGVVYRCVQPSLDRAVAVKVLSTDLDRDN--LERFLREQRAMGRLS
MSMEG_0529|M.smegmatis_MC2_155 GRGGFGVVYRCVQRALDRTVAVKVLTTDLEPDN--LERFMREQVAMGKLS
MLBr_01753|M.leprae_Br4923 LAELSETQPDEAADAIARLDCVVSEAVAAHGGVQQVVQGVRGNFLATFAR
Mvan_5928|M.vanbaalenii_PYR-1 STQLWETQPETMTAAVAQLDRTLTDLVSDHDGVRPVEQGEGDSFVVAFTR
MAB_4435|M.abscessus_ATCC_1997 GRGGMGTVYLAANPNLQRSEALKILSAQSSRDPEFRARFMREASLAASLD
: : . :
MUL_4753|M.ulcerans_Agy99 GHPNIVSVLQIG--ETRDGHPYLVMPYCRRGSVQTEISRLGRLSLADILQ
MMAR_0366|M.marinum_M GHPNIVSVLQIG--ETRDGHPYLVMPYCRRGSVQTEISRLGRLSLADVLQ
MAV_2318|M.avium_104 -DPGLVAVYDQG--LDARHP-FLVMELIEGGTLRELLGERGPMPPYAVAA
TH_2610|M.thermoresistible__bu -DPGLVAVYDQGPGSPASHPPYLVMELIEGGTLRELLRERGPMPPHAAAA
Mflv_1389|M.gilvum_PYR-GCK -HPNIVAIHDFG---EHDSAPFIVMERLPGRTLADVIEQ-GPMPAPQVRR
Mb3107c|M.bovis_AF2122/97 GHPHIVTVLQVG--VLAGGRPFIVMPYHAKNSLETLIRRHGPLDWRETLS
Rv3080c|M.tuberculosis_H37Rv GHPHIVTVLQVG--VLAGGRPFIVMPYHAKNSLETLIRRHGPLDWRETLS
MSMEG_0529|M.smegmatis_MC2_155 GHPNIVNIFQVG--TIASGRPYIVMQYHPHGSLSAKIQAAGPLGWRGALR
MLBr_01753|M.leprae_Br4923 ASDATACALDLQLAPIVPVRFRIALHTGEVQISNDDVNNVVFMMVQAAGL
Mvan_5928|M.vanbaalenii_PYR-1 ASDAVACALALQRAPLAPIRLRIGVHTGEVRLR-DEGNYVGPTINRTARL
MAB_4435|M.abscessus_ATCC_1997 -HPNIVTVHNRG--ETPEGDLWIAMQYVQ-GSDAHSESASGRMSLTRAVH
. : :
MUL_4753|M.ulcerans_Agy99 LGVALAAGLESAHRLDILHRDIKPANVLLTDFGE---------PALTDFG
MMAR_0366|M.marinum_M LGVALAAGLESAHRLDILHRDIKPANVLLTDFGE---------PALTDFG
MAV_2318|M.avium_104 VLRPVLGGLAAAHRAGLVHRDVKPENVLISDDGE---------VKIADFG
TH_2610|M.thermoresistible__bu VLAPVLGGLAVAHRAGLVHRDIKPENVLISDDGE---------VKIADFG
Mflv_1389|M.gilvum_PYR-GCK VLDEVLAALSVAHAAGVLHRDIKPANILLTTAGDS--------VKVADFG
Mb3107c|M.bovis_AF2122/97 IGVKLAGALEAAHRVGTLHRDVKPGNILLTDYGE---------PQLTDFG
Rv3080c|M.tuberculosis_H37Rv IGVKLAGALEAAHRVGTLHRDVKPGNILLTDYGE---------PQLTDFG
MSMEG_0529|M.smegmatis_MC2_155 IGVKMAGALETAHQRDTLHRDVKPANILLTEYGE---------PQLTDFG
MLBr_01753|M.leprae_Br4923 LDLACGGQTVLSSITGDLVVDGLPADTWLVDLGSHLLRDLARPVRVMQLC
Mvan_5928|M.vanbaalenii_PYR-1 RELAHGGQTVLSGTTSDLVADLLPDGGWLSDLGTHRLRDLPRPERVVQLC
MAB_4435|M.abscessus_ATCC_1997 IISEVAKALDYLHARGLVHRDVKPANILLSAGDRR--------IMLGDFG
. : * * . : . : ::
MUL_4753|M.ulcerans_Agy99 LAHMAGGFRTATG--LFTASPAFTASELARGGEPDRASDVYGVGATLFCA
MMAR_0366|M.marinum_M LAHMAGGFRTATG--LFTASPAFTASELARGGEPDRASDVYGVGATLFCA
MAV_2318|M.avium_104 LVRAVAAAGITSAS-VILGTAAYLSPEQVRDGAATPRSDVYAAGILAYEL
TH_2610|M.thermoresistible__bu LVRAVAEAKITSDS-VILGTAAYLSPEQVATGDATPRSDVYAVGILTYEM
Mflv_1389|M.gilvum_PYR-GCK IAKSAGAAHTATG--QIVGTLCYLSPERVMGAPASVADDLYAVGVMGYEA
Mb3107c|M.bovis_AF2122/97 IARIAGGFETATG--VIAGSPAFTAPEVLEGASPTPASDVYSLGATLFCV
Rv3080c|M.tuberculosis_H37Rv IARIAGGFETATG--VIAGSPAFTAPEVLEGASPTPASDVYSLGATLFCA
MSMEG_0529|M.smegmatis_MC2_155 IARIAGGFETAEG--AIMGSPAYTAPEVLLGESPTVASDVYSLASTVFTA
MLBr_01753|M.leprae_Br4923 HRNLRRNLHELGIR-TVPGGPSLPVPLTTFVGRAAQIKELQELLTEKRLL
Mvan_5928|M.vanbaalenii_PYR-1 HADLSNEFPPLRAR-EEIGVQRLPAQLTSFVGRVDDMAQVRGLMDANRLV
MAB_4435|M.abscessus_ATCC_1997 LTRALDDSNSVTSAGNVTATIAYAAPEILSGTAVDGRADVYALGCTLFRM
. ::
MUL_4753|M.ulcerans_Agy99 LTGHPPFERRKGESVIAQILRVANDPVPDLAEYDVAEDVASVVNRALSR-
MMAR_0366|M.marinum_M LTGHPPFERRKGESVIAQILRVANDPVPDLAEYDVAEDVASVVNRALSR-
MAV_2318|M.avium_104 LTGRTPFTGDSTLAIAYRRLDAD-VPPPSAAIDGVPAQFDDFVQRATAR-
TH_2610|M.thermoresistible__bu LTGNTPFTGDNALALAYQRLDND-VPPPSSAISGVPPQFDELVATATAR-
Mflv_1389|M.gilvum_PYR-GCK LLGRRAFPQDNPAALARAIIDVP-PPPLRALSVTADPALVAVIDRAMSR-
Mb3107c|M.bovis_AF2122/97 LTGHAAYERRSGERVIAQFLRITSQPIPDLRKQGLPADVAAAIERAMAR-
Rv3080c|M.tuberculosis_H37Rv LTGHAAYERRSGERVIAQFLRITSQPIPDLRKQGLPADVAAAIERAMAR-
MSMEG_0529|M.smegmatis_MC2_155 STGHAVFERGKGEQMVAQFLRITRHPAPNLRDADLPADLSAAIEQAMSR-
MLBr_01753|M.leprae_Br4923 TLVGPGGVGKTRLALQVVARVADEFSGELSYFDLAPDTDHDIFPITVL--
Mvan_5928|M.vanbaalenii_PYR-1 TLTGAGGVGKTRLATQVAVAVVEGYPGGVWYVDLAPITDPALVAITVARA
MAB_4435|M.abscessus_ATCC_1997 LTGQPPFGSGNSLPAIIN-AHLSAPPPRISQLAPVPESWDALIAKAMAK-
. . . :
MUL_4753|M.ulcerans_Agy99 ------------DPAARP-TMVELGEAIQSLQAAHGQAVDAMALEGGKRS
MMAR_0366|M.marinum_M ------------DPAARP-TMVELGEAIQSLQAAHGQAVDAMALEGGKRS
MAV_2318|M.avium_104 ------------DPADRYADAVEMGADLDAIADELALPGFRVPAPRNS-A
TH_2610|M.thermoresistible__bu ------------DPADRFADAHDMAAAVADLVAELELPPFRVPAPRNS-A
Mflv_1389|M.gilvum_PYR-GCK ------------DPRLRFGSAPQMRAALAGDPLALNNAPPPAPPPRAG-T
Mb3107c|M.bovis_AF2122/97 ------------HPADRPATAADVGEELRDVQRRNGVSVDEMPLPVELGV
Rv3080c|M.tuberculosis_H37Rv ------------HPADRPATAADVGEELRDVQRRNGVSVDEMPLPVELGV
MSMEG_0529|M.smegmatis_MC2_155 ------------TISDRPESAQAFGEQLRELQRRHGLPVDDMPIPIAPPT
MLBr_01753|M.leprae_Br4923 ------------DNLRRCIGDRRMLMVLDNCEYLLDVCANVMTTLLGACP
Mvan_5928|M.vanbaalenii_PYR-1 LGLPDQPGRSTVDTIVRFIADRRMLVVLDNCEHLLDACATLIDALLGACP
MAB_4435|M.abscessus_ATCC_1997 ------------TPADRYQSAGELAMAAQQILTDPAQHRQTVTQPVPATT
* .
MUL_4753|M.ulcerans_Agy99 TSVSSESAWHVSARQTRGNLPAKLAGFVGRQAELAELGALISTSRPVTLT
MMAR_0366|M.marinum_M TSVSSESAWHVSARQTRGNLPAKLAGFVGRQAELAELGALISTSRLVTLT
MAV_2318|M.avium_104 LHRSAALHREAGRRAPGAEPPARHPTRHLTRGPEEWPQPEPPAHVGAEPD
TH_2610|M.thermoresistible__bu QHLSAIRQHSQSAR----------PTTTLQ----------PPXXXGAG--
Mflv_1389|M.gilvum_PYR-GCK RVLAQPLPPSAGFTSAPVGYPTAAPPPPTRARMYLMAVAAVLAFTVAALA
Mb3107c|M.bovis_AF2122/97 ERRRSPEAHAAHRHTGGGTPTVPTPPTPATKYRPSVPTGSLVTRSRLTDI
Rv3080c|M.tuberculosis_H37Rv ERRRSPEAHAAHRHTGGGTPTVPTPPTPATKYRPSVPTGSLVTRSRLTDI
MSMEG_0529|M.smegmatis_MC2_155 DR---PSSIASPTPSSGYPVRTLTPPAPATRFQMPSSAKRLVERARLIDV
MLBr_01753|M.leprae_Br4923 SLTILATSREPIGVAGEVIWRVSMLSPADEAVELFTERAALVQPGFSVTD
Mvan_5928|M.vanbaalenii_PYR-1 ALAMLATSREPIAVAGEQTWRVPPLALDDDAIELFTDRARRARPDFIISA
MAB_4435|M.abscessus_ATCC_1997 PAPIAAPEPVHAMAPLAMADTGQSMLKHKRIAAIIGVMVLVVASSVVAVL
MUL_4753|M.ulcerans_Agy99 GVGGVGKTSLAVQAAGEHVSHFHDGVWLVDIG----------ELSDGALL
MMAR_0366|M.marinum_M GVGGVGKTSLAVQAAGEHVSHFHDGVWLVDIG----------ELSDGALL
MAV_2318|M.avium_104 DDEDDYEYQSVTGEFAGIPISEFV-----------------------WAR
TH_2610|M.thermoresistible__bu ---GRARVATEIGDRIGI--------------------------------
Mflv_1389|M.gilvum_PYR-GCK LALDPFSSPPPMQTVGTSTTAPPPPTSVPPP----------------TSA
Mb3107c|M.bovis_AF2122/97 LRAGGRRRLILIHAPSGFGKSTLAAQWREELSRDGAAVAWLTIDNDDNNE
Rv3080c|M.tuberculosis_H37Rv LRAGGRRRLILIHAPSGFGKSTLAAQWREELSRDGAAVAWLTIDNDDNNE
MSMEG_0529|M.smegmatis_MC2_155 LRAQRDKKLTVIHGPTGFGKSTLAVQWAKQLAADGVAVAWLTVDDDDNNV
MLBr_01753|M.leprae_Br4923 GNRQIVTEICQRLDGMPLAIELAAARIRTLSLTEIADGLDDRFRLLTGGA
Mvan_5928|M.vanbaalenii_PYR-1 DDAAAVSEICHRLDGMPLAIELAAARVRALSLTEIVDGLHDRFRLLTGGS
MAB_4435|M.abscessus_ATCC_1997 IWPRADEGTDPRTKASPSAAQVAPG--------------------ASLAG
MUL_4753|M.ulcerans_Agy99 AGLAARMLGIRDQGARPLTEVLTDALAERDALVIFDGCEHVIDHAAQLID
MMAR_0366|M.marinum_M AGLAARMLGIRDQGARPLTEVLTDALAERDALVIFDGCEHVIDHAAQLID
MAV_2318|M.avium_104 QHNRRMVLVWLALVLAVTGMVATAAWTIGRNLNGLF--------------
TH_2610|M.thermoresistible__bu ----------VDQPPTARGRHANAVRTAFRNDE-----------------
Mflv_1389|M.gilvum_PYR-GCK APLPPPIVPVTQAPPPDNGPKKGPDKKGEKGNNGRGNGNKPD--------
Mb3107c|M.bovis_AF2122/97 VWFLSHLLESIRRVRPTLAESLGHVLEEHGDDAGRYVLTSLIDEIHENDD
Rv3080c|M.tuberculosis_H37Rv VWFLSHLLESIRRVRPTLAESLGHVLEEHGDDAGRYVLTSLIDEIHENDD
MSMEG_0529|M.smegmatis_MC2_155 VWFLSHVIEAIRSVMPALASDLGDVLEEHGDDAERYVLTSLINDIHSSGR
MLBr_01753|M.leprae_Br4923 RTAVRRQQTLRASMDWSYALLTESERALFRRLSAISGTFDLKVAYAVGHD
Mvan_5928|M.vanbaalenii_PYR-1 RTAVRRQQTLRASVDWSHGLLTDPERVLFRRLAVFAGGFDLDGAQAITVD
MAB_4435|M.abscessus_ATCC_1997 QPNTVLDTLLPGQFDYPEGWEKNPSPTFRSGEFNPAVPPGSATNIGGTPV
MUL_4753|M.ulcerans_Agy99 TLLQGCPQLHILATSRELLGIGGEAVLALSPLPYPDAASVSSRSSVARYD
MMAR_0366|M.marinum_M TLLQGCPQLHILATSRELLGIGGEAVLALSPLPYPDAASVSSRSSVARYD
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 RIAVVIDDWHRVSDSRTQAALGFLLDNGCHHLQLIVTSWSRAGLPVGRLR
Rv3080c|M.tuberculosis_H37Rv RIAVVIDDWHRVSDSRTQAALGFLLDNGCHHLQLIVTSWSRAGLPVGRLR
MSMEG_0529|M.smegmatis_MC2_155 RMTLVIDDWHRVTDPATIAALRYLLDNVASGLTVVVTSRTQSGLPMSRMR
MLBr_01753|M.leprae_Br4923 DLEEPDQVFDRLTMLIDKSLVIVEGRQGGSRYRLLETVRQYAMKKLEESN
Mvan_5928|M.vanbaalenii_PYR-1 GEVHRYEVVDLLTLLVDKSLLIAENTAGRTRYRLLETVRQYAQEKLGESG
MAB_4435|M.abscessus_ATCC_1997 GCNTIDPAWALRAKGRETSTLYLRDRKKPEREILIRVVPAADALSTDGAS
MUL_4753|M.ulcerans_Agy99 AVALFVERARTARPGFTLTQRNAAAVARICERLDGLPLAIELAAARLRAV
MMAR_0366|M.marinum_M AVALFVERARTARPGFTLTQRNAAAVARICERLDGLPLAIELAAARLRAM
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 IGDELAEIDSAALR-FDTDEAAALLNDAGGLRLPRADVQALTTSTDGWAA
Rv3080c|M.tuberculosis_H37Rv IGDELAEIDSAALR-FDTDEAAALLNDAGGLRLPRADVQALTTSTDGWAA
MSMEG_0529|M.smegmatis_MC2_155 MQGEIVEIDATALR-FDVSESGSFLVDLAGLDLDQTDVEELTEKTDGWVA
MLBr_01753|M.leprae_Br4923 EVDLVLARHRDHYMALGALLDTPGDIDHEQLVEQVETELDNLRSAFAWSR
Mvan_5928|M.vanbaalenii_PYR-1 EADTLRARHRDHYTARAAELDAPSVAGHERRLNQTDIEMDNLRAAFAWSR
MAB_4435|M.abscessus_ATCC_1997 DALKRCDAVAYIIPGSSTTWRCSFEFDEPNPVQNGQKELTTTESCYMFPS
MUL_4753|M.ulcerans_Agy99 SVEQIADRLSDRFGLLTRGQRGAPTRQQTLSYCIDWSYDHCTPIQQQLWA
MMAR_0366|M.marinum_M SVEQIADRLSDRFGLLTRGQRGAPTRQQTLSYCIDWSYDHCTPIQQQLWA
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 ALRLAALSLRGGGDATQLLRGLSGASDVIHEFLSENVLDTLEPELREFLL
Rv3080c|M.tuberculosis_H37Rv ALRLAALSLRGGGDATQLLRGLSGASDVIHEFLSENVLDTLEPELREFLL
MSMEG_0529|M.smegmatis_MC2_155 ALQLASLTLRDRDDPVQLIETMTGRHHVISEFLAENVLETLEPSTLDFLL
MLBr_01753|M.leprae_Br4923 ETGDIAGALQLASSLQPIWFGRGHMYEGLAWFDSIFEHKNIEHLVAPKEV
Mvan_5928|M.vanbaalenii_PYR-1 ENANTDHSLLLASSLHPLWRARGRLQEGQAWFDAALTDYEARPGEADPAV
MAB_4435|M.abscessus_ATCC_1997 GANSIRQHVSFNVVRGLLVYILASGASNRNDAAGSLSATALSFATTMKIL
MUL_4753|M.ulcerans_Agy99 RLSVFAGSFDLDAAQYVAPQDMDADDLLDELCALVDKSILIRTEDDGAVR
MMAR_0366|M.marinum_M RLSVFAGSFDLDAAQYVAPQDMDADDLLDELCALVDKSILIRTEDDGAVR
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 VASVTER-----TCGGLASALAGITNGRAMLEEAEHRGLFLQRTEDDPNW
Rv3080c|M.tuberculosis_H37Rv VASVTER-----TCGGLASALAGITNGRAMLEEAEHRGLFLQRTEDDPNW
MSMEG_0529|M.smegmatis_MC2_155 ATSIPER-----ICGGLASALTDVPDGQAILEKIEERDLFLRRIDD--QW
MLBr_01753|M.leprae_Br4923 LARAVAN-----KVMLHAILASSPPDGSDLVTQAQQALTMAREIGDSAVL
Mvan_5928|M.vanbaalenii_PYR-1 YARALAD-----RAFMDGHVG-----ITDRLDQAQKALAMARDIDDPALL
MAB_4435|M.abscessus_ATCC_1997 RYGR----------------------------------------------
MUL_4753|M.ulcerans_Agy99 FRLLSTM--REYGNSRIDAEQYQGLQQSHFDWCERLVTQAHLEWFSRKQV
MMAR_0366|M.marinum_M FRLLSTM--REYGNSRIDAEQYQGLQQSHFDWCERLVTQAHLEWFSQKQV
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 FRFHQMF--ADFLHRRLERGGSHRVAELHRRASAWFAENGYLHEAVDHAL
Rv3080c|M.tuberculosis_H37Rv FRFHQMF--ADFLHRRLERGGSHRVAELHRRASAWFAENGYLHEAVDHAL
MSMEG_0529|M.smegmatis_MC2_155 FRYHQLF--RDFLRHRLSR---ERVCDLHRRACRWYAGQRLVREAVDHAL
MLBr_01753|M.leprae_Br4923 ARALTACGFSSGYDTEVARPYFAEAVELARTQGDKWTLSQIRLWGVVGFC
Mvan_5928|M.vanbaalenii_PYR-1 VRALTACGGLAAYNADVARPLLAEAVDLARSMGDKWMLAETLAWQAYAAL
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 DWIHRLRSELPNIEEALQFGLEKAPESVLLMAAKLRN-LFVVSGKLQVGR
MMAR_0366|M.marinum_M DWIHRLRSELPNIEEALQFGLEKAPESVLLMAAKLRN-LFVASGKLQVGR
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 AAGDPARAVDLVEQDETNLPEQSKMTTLLAIVQKLPTSMVVSRARLQLAI
Rv3080c|M.tuberculosis_H37Rv AAGDPARAVDLVEQDETNLPEQSKMTTLLAIVQKLPTSMVVSRARLQLAI
MSMEG_0529|M.smegmatis_MC2_155 AAGDETEAVRLVENDGLYLVSGGQMATLIGLTAKLPQDIVRSNPRLQLAL
MLBr_01753|M.leprae_Br4923 VSG-DPVALRAAAEAADDLAQEIGDRFVSLQCRLLLSIAQLWQGDMDGAI
Mvan_5928|M.vanbaalenii_PYR-1 MGGGDPVAARTAGEEARELADEMGDGFVSRICGWLLGIAHHFQGDLDAAL
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 LWVERALSTTTSAQPSGARIAALAALAMFAVLQTDWPTAQSCVAQAHEHG
MMAR_0366|M.marinum_M LWVERALSTTTSAQPSGARIAALAALAMFAVLQTDWPTAQSCVAQAHEHG
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 AWANILLQRPAPATGALNRFETALGRAELPEATQADLRAEADVLRAVAEV
Rv3080c|M.tuberculosis_H37Rv AWANILLQRPAPATGALNRFETALGRAELPEATQADLRAEADVLRAVAEV
MSMEG_0529|M.smegmatis_MC2_155 AWANIVLHRVPAARDALARVEATMADAGLSEDEIADMRAEADVVRAIADL
MLBr_01753|M.leprae_Br4923 VRSGEVVAGAEAAHDTVTRTFGLYVQTRALVHR-DVSAALVTAGLVVEAA
Mvan_5928|M.vanbaalenii_PYR-1 ALADGVVSESDVAHDTLNGCCGELVLAHSLAQRGDTDAARAAAQVSLNVA
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 AAVPDPIAESLLGVARGLGALLQGQVEQVQTDAEQGLAAGDFELQVLG--
MMAR_0366|M.marinum_M AAVPDPIAESLLGVARGLGALLQGQVEQVQTDAEQGLAAGDFELQVLG--
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 FADRVERVDDLLAEAMSRPDTLPPRVPGTAGNTAALAAICRFEFAEVYPL
Rv3080c|M.tuberculosis_H37Rv FADRVERVDDLLAEAMSRPDTLPPRVPGTAGNTAALAAICRFEFAEVYPL
MSMEG_0529|M.smegmatis_MC2_155 RSDRLSGIDEHVAACLQRRDRMPPFSVATAATVATFAAAYRYDLDEVERI
MLBr_01753|M.leprae_Br4923 AELSGVYQGIGYAAMVFAALAMGDVAAAVEASEACRPHLGADHGLVAIHL
Mvan_5928|M.vanbaalenii_PYR-1 VEVSPVHAGLAHAALAVANLAAGDVTAAEAASDSATRSFGPSEVAGIQDP
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0366|M.marinum_M --------------------------------------------------
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 LDWAAPYQEMMG-PFGTVYAQCLRGMAARNRLDIVAALQNFRTAFEVGTA
Rv3080c|M.tuberculosis_H37Rv LDWAAPYQEMMG-PFGTVYAQCLRGMAARNRLDIVAALQNFRTAFEVGTA
MSMEG_0529|M.smegmatis_MC2_155 QTWAAPYYERSGDAFSIVNGLCFCGIAHHLMLNNAVAEQTLRRALRIAKR
MLBr_01753|M.leprae_Br4923 ELMAAVALARG---------------------------DVIVARRLADNS
Mvan_5928|M.vanbaalenii_PYR-1 NVAAQIACTRG---------------------------DLDTARSLVDGA
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 ------------MWLMPLRHLAVGDPEPALRWAEKAHSVSESRVEVQMRT
MMAR_0366|M.marinum_M ------------MWLMSLRHLAVGDPEPALRWAEKAHSVSESRVEVQMRT
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 VG-AHSHAARLAGSLLAELLYETGDLAGAGRLMDESYLLGSEGGAVDYLA
Rv3080c|M.tuberculosis_H37Rv VG-AHSHAARLAGSLLAELLYETGDLAGAGRLMDESYLLGSEGGAVDYLA
MSMEG_0529|M.smegmatis_MC2_155 SGGIHSYAGRLASSLLGEILYEKGDLAEAERLLDEGYKLGPEGGSVDFKI
MLBr_01753|M.leprae_Br4923 VSATTGWHQMAALTTRARIAMAQGEPELARADIHAALACGADIQASLGIS
Mvan_5928|M.vanbaalenii_PYR-1 VSITRGVHRASALTTRARIAIAQGDPEQAERNAHDALSLAAGVGARLEVP
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 YSLSALAVSHLMLGDTGSAERSLREG------------------------
MMAR_0366|M.marinum_M YSLSALAVSHLMLGDTGSAERSLREG------------------------
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 ARYVIGARVKAAQGDHEGAADRLSTGGDTAVQLGLPRLAARINNERIRLG
Rv3080c|M.tuberculosis_H37Rv ARYVIGARVKAAQGDHEGAADRLSTGGDTAVQLGLPRLAARINNERIRLG
MSMEG_0529|M.smegmatis_MC2_155 ARYVISARIKALQGDRLGAAQRLDEATRVARSLSLNRLQALAEHERIRLG
MLBr_01753|M.leprae_Br4923 DSMELLAELISQGDNHRQAGRLFGAASAQREKTGEVRFKVWDAGYESAVA
Mvan_5928|M.vanbaalenii_PYR-1 DTLECLARVVGDGGSHHEAARLCGAAEAIRGRTGAVRFRIYDADHETTVT
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 --------LKLCQVIDDPWSGASYLEGLAWTAGANGNLRRAVVLMAAAAA
MMAR_0366|M.marinum_M --------LKLCQVIDDPWSGASYLEGLAWTAGANGNLRRAVVLMAAAAA
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 IALPAAVAADLLAPRTIPRD--NGIATMTAELDEDSAVR-LLSAGDSADR
Rv3080c|M.tuberculosis_H37Rv IALPAAVAADLLAPRTIPRD--NGIATMTAELDEDSAVR-LLSAGDSADR
MSMEG_0529|M.smegmatis_MC2_155 LPPHPEFGPMPVVSYDARREPVDAMDAIALQFEEASAIRRLMASDDPAAR
MLBr_01753|M.leprae_Br4923 VLRGAMGCKDFDSAWAEGAAMPIDDAITYAQRGRGNRKRPTTGWESLTPA
Mvan_5928|M.vanbaalenii_PYR-1 TLRDALGDKAFEAAWTEGSATSITEAIAYAQRGRGERKRPSSGWASLTPT
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 LSRSSGAGSTVIALVGSMHQQCERAAREELSDAVFETARVEGESLSFDDA
MMAR_0366|M.marinum_M LSRSSGAGSTVIALVGSMHQQCERAAREELSDAVFEAARVEGESLSFDEA
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 DQACQRAGALAAAIDGTRRPLAALQAQILHIETLAATGRESDARNELAPV
Rv3080c|M.tuberculosis_H37Rv DQACQRAGALAAAIDGTRRPLAALQAQILHIETLAATGRESDARNELAPV
MSMEG_0529|M.smegmatis_MC2_155 DLACRWAREWVDRLSALNRPQALLRARRLLGACLAADGRTAEAKAMVATV
MLBr_01753|M.leprae_Br4923 EHNVIRLVSEGLDTKDIAARLFVSVRTVHTHLTRIYSKLGLTSRVQLVQE
Mvan_5928|M.vanbaalenii_PYR-1 ELDVVGLVSEGLSNKDIAARLFVSPRTVQTHLTHVYTKLCLASRVQLAQE
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 ADVALTEP------------------------------------------
MMAR_0366|M.marinum_M AAVALTEP------------------------------------------
MAV_2318|M.avium_104 --------------------------------------------------
TH_2610|M.thermoresistible__bu --------------------------------------------------
Mflv_1389|M.gilvum_PYR-GCK --------------------------------------------------
Mb3107c|M.bovis_AF2122/97 ATKCAELGLSRLLVDAGLA-------------------------------
Rv3080c|M.tuberculosis_H37Rv ATKCAELGLSRLLVDAGLA-------------------------------
MSMEG_0529|M.smegmatis_MC2_155 AAQCAQLRMLRYLVDGGPQVVATLVELRADQEAGRWSPEWPEVPADFLQD
MLBr_01753|M.leprae_Br4923 AARHN---------------------------------------------
Mvan_5928|M.vanbaalenii_PYR-1 AARHT---------------------------------------------
MAB_4435|M.abscessus_ATCC_1997 --------------------------------------------------
MUL_4753|M.ulcerans_Agy99 ----------
MMAR_0366|M.marinum_M ----------
MAV_2318|M.avium_104 ----------
TH_2610|M.thermoresistible__bu ----------
Mflv_1389|M.gilvum_PYR-GCK ----------
Mb3107c|M.bovis_AF2122/97 ----------
Rv3080c|M.tuberculosis_H37Rv ----------
MSMEG_0529|M.smegmatis_MC2_155 AINSVAPQRY
MLBr_01753|M.leprae_Br4923 ----------
Mvan_5928|M.vanbaalenii_PYR-1 ----------
MAB_4435|M.abscessus_ATCC_1997 ----------