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SKTVVIGASSGLGRCIGVGLARRGDHVALLARRRERTEAAAKEAGPGTVAVECDVTDEASCRSALAAAAD ALGGIDNLVYAPAISPLVRLAETDADTWRRVFDTNVIGASLATAAALPHLRAAAGKAVYLSSDAGSHAPP WPGLGAYGVSKAALERLVEAWRAEHPEIGFTCVIVGECAGGEGDAQTGMNIGWDRELAMKAYPLWLARGC MPGKLMPVEDLVNIVHTILRTDAATSIPVVIARGASAPAGVLDAGQS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3514 | - | - | 100% (258) | oxidoreductase |
| M. marinum M | MMAR_0058 | - | 2e-16 | 30.90% (178) | short-chain type oxidoreductase |
| M. marinum M | MMAR_4931 | - | 2e-16 | 34.02% (194) | short-chain alcohol dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1976 | - | 1e-17 | 31.47% (232) | short-chain type dehydrogenase/reductase |
| M. gilvum PYR-GCK | Mflv_0854 | - | 2e-18 | 35.03% (177) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv1941 | - | 1e-17 | 31.47% (232) | short-chain type dehydrogenase/reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 1e-08 | 23.93% (234) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_4922 | - | 5e-18 | 35.56% (180) | putative short-chain dehydrogenase/reductase |
| M. avium 104 | MAV_4099 | - | 1e-119 | 78.82% (255) | NAD dependent epimerase/dehydratase family protein |
| M. smegmatis MC2 155 | MSMEG_4742 | - | 8e-32 | 33.06% (242) | clavaldehyde dehydrogenase |
| M. thermoresistible (build 8) | TH_4232 | - | 1e-68 | 54.85% (237) | PUTATIVE putative NAD dependent epimerase/dehydratase family |
| M. ulcerans Agy99 | MUL_2753 | - | 1e-129 | 90.70% (258) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_6051 | - | 4e-18 | 33.90% (177) | short chain dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3514|M.marinum_M --------------MS------KTVVIGASSGLGRCIGVGLARRGDHVAL
MUL_2753|M.ulcerans_Agy99 --------------MS------KTVVIGASSGLGRCIGVGLARRGDHVAL
MAV_4099|M.avium_104 ------------------------MVVGASSGLGRCIGVGLAQRGDRVAL
TH_4232|M.thermoresistible__bu --------------MSEPDRPLRVAVVGASAGLGRCIGVGLSERGAQVAM
MSMEG_4742|M.smegmatis_MC2_155 -----------MSSQPPDAAGLRLLVVGASSGIGHAVAESAAKRGIDVAV
Mflv_0854|M.gilvum_PYR-GCK --------------------MPTAMITGASGGLGSALADALAPT-HTLFL
Mvan_6051|M.vanbaalenii_PYR-1 --------------------MPTAMITGASGGVGSALADALAPT-HTLFL
MAB_4922|M.abscessus_ATCC_1997 --------------------MPHALITGAAGGLGAAIARALAAT-HSLLL
Mb1976|M.bovis_AF2122/97 -------------MNHPDLAGKVAIVTGAGAGIGLAVARRLADEGCHVLC
Rv1941|M.tuberculosis_H37Rv -------------MNHPDLAGKVAIVTGAGAGIGLAVARRLADEGCHVLC
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
: *. *:* .:. :
MMAR_3514|M.marinum_M LARRRERTEAAAKEAGPGTVAVECDVTDEASCRSALAAAADALGGIDNLV
MUL_2753|M.ulcerans_Agy99 LARRRER--------------------DEASCRSTLAAAADALGGIDNLV
MAV_4099|M.avium_104 LARRRQRIEAAAKDAGPGAVAIECDVTDQASCASAIGEAVDALGGIDNIV
TH_4232|M.thermoresistible__bu LARRRERLADAAREAGNGAVPVVCDVTDQGSCRRAMSEVVDALGRLDALV
MSMEG_4742|M.smegmatis_MC2_155 AARRIKLLKTLADSIG--GHAFELDVEDPAAITRVVNEAADALGGLDAVV
Mflv_0854|M.gilvum_PYR-GCK AGRPSPRLDAVAERLG--ATTWPVDLADPD----AMAAVVEPIVELDVLI
Mvan_6051|M.vanbaalenii_PYR-1 AGRPSPRLDAVAERLG--ATTWPVDLADPD----AIPAVVEPIVELDVLI
MAB_4922|M.abscessus_ATCC_1997 GGRPSLRLDTLADELD--ATPWPVDLSDQD----AILAAVAGIDALDVLV
Mb1976|M.bovis_AF2122/97 ADIDGDAADAAATKIGCGAAACRVDVSDEQQIIAMVDACVAAFGGVDKLV
Rv1941|M.tuberculosis_H37Rv ADIDGDAADAAATKIGCGAAACRVDVSDEQQIIAMVDACVAAFGGVDKLV
MLBr_01807|M.leprae_Br4923 THR--------ASVVPDWFFGVECDVTDNDAIGAAFKAVEEHQGPVEVLV
* . :: ::
MMAR_3514|M.marinum_M YAPAISPLVRLAETDADTWRRVFDTNVIGASLATAAALP-HLRAAAGKAV
MUL_2753|M.ulcerans_Agy99 YAPAISPLVRLAETDADTWRRVFDTNVIGASLATAAALP-HLRAAAGKAV
MAV_4099|M.avium_104 YTPAVGPLVRMVDTDADTWRRIFDTNVIGASLVTAAAVP-HLSASAGKAV
TH_4232|M.thermoresistible__bu YTTGMGILSPLVEMTADQWAQLFATNVTGAALITAAAAP-HLSAAGGSAV
MSMEG_4742|M.smegmatis_MC2_155 FTSTVIPFAYIEDTDVASWLHAFNVNTLGANNVLRAAVP-RLADNG---V
Mflv_0854|M.gilvum_PYR-GCK HNAGVAYPGRVAESHVDEWRSTMAVNVVGAVALTLELLP-ALRAARGHVV
Mvan_6051|M.vanbaalenii_PYR-1 HNAGVAYPGRVAESDVDQWRATMAVNVVGAVALTLELLP-ALRSAGGHVV
MAB_4922|M.abscessus_ATCC_1997 HNAGVSYPATIADSTLADWRKTLDVNVLAPVALTQALLP-ALRAAQGDVV
Mb1976|M.bovis_AF2122/97 ANAGVVHLASLIDTTVEDFDRVIAINLRGAWLCTKHAAPRMIERGGGAIV
Rv1941|M.tuberculosis_H37Rv ANAGVVHLASLIDTTVEDFDRVIAINLRGAWLCTKHAAPRMIERGGGAIV
MLBr_01807|M.leprae_Br4923 ANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRFGRYI
. : : : : * . : :
MMAR_3514|M.marinum_M YLSSDAGSHAPPWPGLGAYGVSKAALERLVEAWRAEHPEIGFTCVIVGEC
MUL_2753|M.ulcerans_Agy99 YLSSDAGSHAPPWPGLGAYGVSKAALERLVEAWRAEHPEIGFTCVVVGEC
MAV_4099|M.avium_104 YLSSDAGAFGPPWPGLGAYGVSKAALERLVEAWRAEHPDIGFTCLIVGEC
TH_4232|M.thermoresistible__bu YLSSLSASYTTPWPRLGSYAVTKAALDKLVEAWRVEHPEIGFTRLAVGDS
MSMEG_4742|M.smegmatis_MC2_155 VLIASSHDVGRPRAGVAAYSASKAALDEILHSWRSEHPELSVIRVGVGPT
Mflv_0854|M.gilvum_PYR-GCK FINSGAGINASP--GLASYTASKFALRGFADSLRADEPTLRVTSVHP---
Mvan_6051|M.vanbaalenii_PYR-1 FINSGAGINASP--GLASYSASKFALRAFADSLRADEPGLRVTSVHP---
MAB_4922|M.abscessus_ATCC_1997 FINSGAGINAHP--GIGSYSVSKFALRGFADVLRAEEPALRVTSVHP---
Mb1976|M.bovis_AF2122/97 NLSSLAGQVAVG--GTGAYGMSKAGIIQLSRITAAELRSSGIRSNTLLP-
Rv1941|M.tuberculosis_H37Rv NLSSLAGQVAVG--GTGAYGMSKAGIIQLSRITAAELRSSGIRSNTLLP-
MLBr_01807|M.leprae_Br4923 FMGSVVGLSGVP--GQANYAASKSGLIGMARSLARELGSRSITANVVAP-
: : . * :* .: : : .
MMAR_3514|M.marinum_M AGGEGDAQTGMNIGWDRELAMKAYPLWLA-------RGCMPGKLMPVEDL
MUL_2753|M.ulcerans_Agy99 AGGEGDAQTGTNIGWDRELAMKAYLLWLA-------RGCMPGKLMPVEDL
MAV_4099|M.avium_104 AGGEGDGQTGMNQGWDMDLAMKAVPLWSS-------RGCMPGKLMPVEDL
TH_4232|M.thermoresistible__bu LGGTGDSQTEFNKSWDPAAFDDAVNFWME-------HGYMQGGLVEADHL
MSMEG_4742|M.smegmatis_MC2_155 ED------TEILRGADRDLLDQLLKLWVE-------QGALPARMSALGDV
Mflv_0854|M.gilvum_PYR-GCK -------------GRIATAMQEDLVAYEG-------RPYEPDRFLSPQTV
Mvan_6051|M.vanbaalenii_PYR-1 -------------GRIATAMQEDLVAYEG-------RPYDPAQFLSPQTV
MAB_4922|M.abscessus_ATCC_1997 -------------GRISTPMQQELTEHEG-------REYNPDDYMRPESV
Mb1976|M.bovis_AF2122/97 ---------AFVDTPMQQTAMAMFDGALGAGGARSMIARLQGRMAAPEEM
Rv1941|M.tuberculosis_H37Rv ---------AFVDTPMQQTAMAMFDGALGAGGARSMIARLQGRMAAPEEM
MLBr_01807|M.leprae_Br4923 ---------GFIDTEMTRAMDSKYQEAA-------LQAIPLGRIGAVEEI
:
MMAR_3514|M.marinum_M VNIVHTILRTDAA--TSIPVVIARGASAP-AGVLDAGQS
MUL_2753|M.ulcerans_Agy99 VNIVHTILRTDAA--TSIPVVIARGASAP-AGVLDAGQS
MAV_4099|M.avium_104 IDVVHTILRTNAS--TSMPLVVARGAPASQAAFAEANQS
TH_4232|M.thermoresistible__bu VQTVDAILRCGKS--SFIPHLTLAPRPSS--AVDDLR--
MSMEG_4742|M.smegmatis_MC2_155 ANTLVSLVVTAFENPTVVPEVVQLSPRIRRRQGREPAE-
Mflv_0854|M.gilvum_PYR-GCK ARLTVDAINAPAD--AHVHEVIIRPSPAPR---------
Mvan_6051|M.vanbaalenii_PYR-1 AQVTADAINAPAD--AHIHEVIVRPR-------------
MAB_4922|M.abscessus_ATCC_1997 AQLVADAVNLPRD--ARVHQIVVRQN-------------
Mb1976|M.bovis_AF2122/97 AGIVVFLLSDDAS---MITGTTQIADGGTIAALW-----
Rv1941|M.tuberculosis_H37Rv AGIVVFLLSDDAS---MITGTTQIADGGTIAALW-----
MLBr_01807|M.leprae_Br4923 AGAVSFLASEDAG---YISGAVIPVDGGLGMGH------
: