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MRRLSSVDAQFFAMEDGRNHSHVCQLTIVEATTTDGLRLDGQRIRGLLAQRIDLMPPLRWRVREVPFGID YPVLVQDDTFDLDSHLWESALPAPGDDEQLGRAVADIASRPLDRARPLWELHVIHGLAGDRVALVTKLHH SVIDGVSGMELLGALLDTVPFPDAGPELEKPPTGTAIGNAPSDAGLLARALASLPVQPARMVRGLPPMLR HIDQLPTMRHLPGAAVIAKVADRAERLATRNKDGRNLQHPRAAAPKVSFGGRISAQRRFAFGSLPLDQIK AAKFAVPGATVNDVVVAVCAGALRRRMIARGDDVATPLVAMVPVSVRTGERQYGNQISSMIVPIPTDQAD ARTRLISAHQVMRAAKERHRAIPAKLLTEANHTVPPALLTRAARVISMTTGSGWIRPPFNVTISNIPGSP DPLYCAGARVVSQHPVNVLLDGMGLSITLLSYQDRLDFGLTADRELLPDVWHLADELAAELSALAAEVGA PRNPVADGAPTGTTGRPTAKPGAIPR
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_3330 | - | - | 100% (516) | hypothetical protein MMAR_3330 |
M. marinum M | MMAR_1605 | - | e-134 | 50.51% (491) | hypothetical protein MMAR_1605 |
M. marinum M | MMAR_3329 | - | e-102 | 41.62% (495) | hypothetical protein MMAR_3329 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1460 | - | 5e-73 | 37.07% (491) | hypothetical protein Mb1460 |
M. gilvum PYR-GCK | Mflv_0349 | - | 4e-72 | 35.96% (495) | hypothetical protein Mflv_0349 |
M. tuberculosis H37Rv | Rv1425 | - | 2e-72 | 37.07% (491) | hypothetical protein Rv1425 |
M. leprae Br4923 | MLBr_01244 | - | 3e-21 | 27.32% (366) | hypothetical protein MLBr_01244 |
M. abscessus ATCC 19977 | MAB_0507 | - | 2e-73 | 36.97% (495) | hypothetical protein MAB_0507 |
M. avium 104 | MAV_2240 | - | 5e-70 | 35.70% (493) | acyltransferase, ws/dgat/mgat subfamily protein |
M. smegmatis MC2 155 | MSMEG_4297 | - | 3e-71 | 35.85% (491) | acyltransferase, ws/dgat/mgat subfamily protein |
M. thermoresistible (build 8) | TH_2477 | - | 1e-64 | 33.00% (497) | PUTATIVE acyltransferase, ws/dgat/mgat subfamily protein |
M. ulcerans Agy99 | MUL_1313 | - | 0.0 | 99.22% (516) | hypothetical protein MUL_1313 |
M. vanbaalenii PYR-1 | Mvan_3601 | - | 4e-71 | 35.03% (491) | hypothetical protein Mvan_3601 |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_3330|M.marinum_M ---------------MRRLSSVDAQFFAMEDGRNHSHVCQLTIVEATTTD MUL_1313|M.ulcerans_Agy99 ---------------MRRLSSVDAQFFAMEDGRNHSHVCQLTIVEATTTD MSMEG_4297|M.smegmatis_MC2_155 ---------------MQRLSGLDASFLYLETAAQPMHVCSVLELDTSTMP Mvan_3601|M.vanbaalenii_PYR-1 MDLLTPAPPRHTIGGMQRLSGLDASFLYLESAAQPLHVCSILELDTSTMP TH_2477|M.thermoresistible__bu ------VPPPYDRG-MQRLSGLDASFLYLETPDQPLHVCSILELDTSTIP MAV_2240|M.avium_104 ------------MLRMQRLSGLDASFLYLETSSQPMHVCSIIELDTSTVP Mb1460|M.bovis_AF2122/97 ---------------MKRLSSVDAAFWSAETAGWHMHVGALAICDPSDAP Rv1425|M.tuberculosis_H37Rv ---------------MKRLSSVDAAFWSAETAGWHMHVGALAICDPSDAP MAB_0507|M.abscessus_ATCC_1997 ---------------MQRLSGVDAAFWHAETAGWHMHIGGLSIYDPTDAP Mflv_0349|M.gilvum_PYR-GCK ----------------MRLSSVDAAFWFAENLKWHMHIGAIALCDPSDVP MLBr_01244|M.leprae_Br4923 -----MADSVEGIGPFDELGALDYLLHRGEAN--PRTRAGIMAVELLDTT .*..:* : * : : MMAR_3330|M.marinum_M GLRLDGQRIRGLLAQRIDLMPPLRWRVREVPFGIDYPVLVQDDTFDLDSH MUL_1313|M.ulcerans_Agy99 GLRLDGQRIRGLLAQRIDLMPPLRWRVREVPFGIDYPVLVQDDTFDLDSH MSMEG_4297|M.smegmatis_MC2_155 G-GYTFDRLRDALSLRIKAMPEFREKLADSRFNLDHPVWVEDNDFDVDRH Mvan_3601|M.vanbaalenii_PYR-1 G-GYTFDRLRDGLALRIKAMPEFREKIADSRFNLDHPVWVEDNDFDVDRH TH_2477|M.thermoresistible__bu G-GYDFHQLREALLLRIKAMPEFREKLADNRFNLDHPVWVEDADFDVDRH MAV_2240|M.avium_104 G-GYTFERLRDALVRRIRAVPPFREKLADSPLNLDHPVWVDDEDFDVDRH Mb1460|M.bovis_AF2122/97 --EYSFQRLRELIIERLPEIPQLRWRVTGAPLGLDRPWFVEDEELDIDFH Rv1425|M.tuberculosis_H37Rv --EYSFQRLRELIIERLPEIPQLRWRVTGAPLGLDRPWFVEDEELDIDFH MAB_0507|M.abscessus_ATCC_1997 --DYSFERVRALIVERLPSMPQLRWRVTDVPLGLDRPWFVEDEELDPDFH Mflv_0349|M.gilvum_PYR-GCK --DFGFEQVRDLIISRLPELPQLRWRVVGAPLGLDRPYFVEDEDIDVDFH MLBr_01244|M.leprae_Br4923 P---DWNRFRSRIEDVSQRVLRLRQKVVVPTLPTAAPRWVVDPDFELDFH .:.* : : :* :: : * * * :: * * MMAR_3330|M.marinum_M LWESALPAPGDDEQLGRAVADIASRPLDRARPLWELHVIHGLA------G MUL_1313|M.ulcerans_Agy99 LWESALPAPGDDEQLGRAVADIASRPLDRARPLWELHVIHGLA------G MSMEG_4297|M.smegmatis_MC2_155 LHRIGLPGPGGRAELAEICGHIASLPLDRSRPLWEMWVIENVAGTDAHAG Mvan_3601|M.vanbaalenii_PYR-1 LHRIGLPSPGGRVELAEICGHIASLPLDRTRPLWEMWVIENVAGTDAHAG TH_2477|M.thermoresistible__bu LHRIGLPAPGGPAELAEICGHLAALPLDRSRPLWEMWVIENIDGTDPRSG MAV_2240|M.avium_104 LHRIAVPAPGGRAELSQICGHIAQTPLDRRRPLWEMWVIEGVAGTDCHRD Mb1460|M.bovis_AF2122/97 IRRIGVPAPGGRRELEELVGRLMSYKLDRSRPLWELWVIEGVE------G Rv1425|M.tuberculosis_H37Rv IRRIGVPAPGGRRELEELVGRLMSYKLDRSRPLWELWVIEGVE------G MAB_0507|M.abscessus_ATCC_1997 IRRIGVPAPGGRKELEELAGRLMSYKLDRSRPLWELWVIEGVE------G Mflv_0349|M.gilvum_PYR-GCK IRRIAVPSPGGRKELDDLVGRLMSYKLDRSKPLWELWFIEGLE------G MLBr_01244|M.leprae_Br4923 VRRVRVPDPGTLREVFDLAEVIQQSPMDVSRPLWTATLVEGLA------A : . :* ** :: : :* :*** .:..: MMAR_3330|M.marinum_M DRVALVTKLHHSVIDGVSGMELLGALLDTVPFPDAGPELEK------PPT MUL_1313|M.ulcerans_Agy99 DRVALVTKLHHSVIDGVSGMELLGALLDTVSFPDAGPELEK------PPT MSMEG_4297|M.smegmatis_MC2_155 GRLALMTKVHHASVDGVTGANLLSQLCTTEPDAPP-PDP----------- Mvan_3601|M.vanbaalenii_PYR-1 GRIAVMTKVHHAAVDGVTGANLMSKLCTTEPDAPP-PDP----------- TH_2477|M.thermoresistible__bu GPLVVLTKVHHAAVDGVTGANLLSQVCTTEADTPP-PEP----------- MAV_2240|M.avium_104 GRLAVMTKVHHAGVDGVTGANLMSQLCATEPDAAP-PEP----------- Mb1460|M.bovis_AF2122/97 GRIATLTKMHHAIVDGVSGAGLGEILLDITPEPRP-PQQET------VG- Rv1425|M.tuberculosis_H37Rv GRIATLTKMHHAIVDGVSGAGLGEILLDITPEPRP-PQQET------VG- MAB_0507|M.abscessus_ATCC_1997 GRVATLTKMHHAIVDGVSGAGLGEILLDIAPEPRP-APDDT------VGS Mflv_0349|M.gilvum_PYR-GCK GRVAVVTKMHHAVVDGVSGAGISEILLDTTPEPRP-PAVDA------SRS MLBr_01244|M.leprae_Br4923 GRAAMLLQISHAITDGVGSVEMFAEMYDLERDPPSRPRSPQPIPQDLSRN . . : :: *: *** . : : . . . MMAR_3330|M.marinum_M GTAIGNAPSDAGLLARALASLPVQPARMVRGLPPMLRHIDQLPTMRHLPG MUL_1313|M.ulcerans_Agy99 GTAIGNASSDAGLLARALASLPVQPARMVRGLPPMLRHIDQLPTMRHLPG MSMEG_4297|M.smegmatis_MC2_155 VDGPGGGTGLEIAVNGAVRFATR-PLRLVN-------------------- Mvan_3601|M.vanbaalenii_PYR-1 VAGPGGGTDLEIAVSGAVRFATR-PLKLVN-------------------- TH_2477|M.thermoresistible__bu VQGAGTASDLEIALSGAVRFATR-PLKLLN-------------------- MAV_2240|M.avium_104 AAGVGGGAGWRIAAGGLVRFAAR-PLRLAS-------------------- Mb1460|M.bovis_AF2122/97 FVGFQIPGLERRAIGALINVGIMTPFRIVR-------------------- Rv1425|M.tuberculosis_H37Rv FVGFQIPGLERRAIGALINVGIMTPFRIVR-------------------- MAB_0507|M.abscessus_ATCC_1997 LVGLGLPSRERILLSALVNVGVKTPYRVAR-------------------- Mflv_0349|M.gilvum_PYR-GCK LVGVKPPSRERQAVNGLINVWFKTPYRITR-------------------- MLBr_01244|M.leprae_Br4923 DLMLQGINHLPVALAGGVVGGLSGVASVAG-------------------- : : MMAR_3330|M.marinum_M AAVIAKVADRAERLATRNKDGRNLQHPRAAAPKVSFGGRISAQRRFAFGS MUL_1313|M.ulcerans_Agy99 AAVIAKVADRAERLATRNKDGRNLQHPRAAAPKVSFGGRISAQRRFAFGS MSMEG_4297|M.smegmatis_MC2_155 --VVPSTLNTVVDTVRRARNGR-TMAAPFAAPRTAFNANITGHRNIAFAQ Mvan_3601|M.vanbaalenii_PYR-1 --VVPNTVSTVIDTVKRARNGL-TMAPPFAAPKTAFNANVTGHRNVAFAQ TH_2477|M.thermoresistible__bu --VLPTTANSVLDTVRRARAGR-TMARPFAAPSTPFNANVTGRRNVAFTQ MAV_2240|M.avium_104 --VVPDTAASVLATVRRALDGA-AMARPFAAPTTVFNARISNRRCIAYAE Mb1460|M.bovis_AF2122/97 --LLEQTVRQQIAALGVAGKP----ARYFEAPKTRFNAPVSPHRRVTGTR Rv1425|M.tuberculosis_H37Rv --LLEQTVRQQIAALGVAGKP----ARYFEAPKTRFNAPVSPHRRVTGTR MAB_0507|M.abscessus_ATCC_1997 --LVQQTVRQQLAVFGMERKS----PGYFEAPHTRFNAPVSPHRRISGAR Mflv_0349|M.gilvum_PYR-GCK --LLEQTVRQQIAVRNIDNKP----PRYFDAPKVRFNGPISPHRSVAGAS MLBr_01244|M.leprae_Br4923 -RAILRPASTVSGVVGYVRSG--IRVLSQAAEPSPLLRQRSLATRTEAIE : * : : MMAR_3330|M.marinum_M LPLDQIKAAKFAVPGATVNDVVVAVCAGALRRRMIARGDDVATPLVAMVP MUL_1313|M.ulcerans_Agy99 LPLDQIKAAKFAVPGATVNDVVVAVCAGALRRRMIARGDDVATPLVAMVP MSMEG_4297|M.smegmatis_MC2_155 LDLEDIKTVKNHF-DVKVNDVVMALVSGVLRTFLSHRDELPDNSLVAMVP Mvan_3601|M.vanbaalenii_PYR-1 LDLEDIKTVKNHF-GVKVNDVVMALVSGVLRTFLLERGELPESSLVAMVP TH_2477|M.thermoresistible__bu LDLEDVKRIKDHF-GVKVNDVVMALTSGALRSYLLERDQLPDSPLIAMVP MAV_2240|M.avium_104 LNLDDVKAVKNHF-GVKVNDVVMALVSGVLRQYLAERNALPDSSLVASVP Mb1460|M.bovis_AF2122/97 VELARAKAVKDAF-GVKLNDVVLALVAGAARQYLQKRDELPAKPLIAQIP Rv1425|M.tuberculosis_H37Rv VELARAKAVKDAF-GVKLNDVVLALVAGAARQYLQKRDELPAKPLIAQIP MAB_0507|M.abscessus_ATCC_1997 LDLARVKALKDAF-GVKVNDVVLAIVAGAVRDYLAKRDEFPDKPLIVQIP Mflv_0349|M.gilvum_PYR-GCK VPLDRVKAVKNAF-DVKLNDVVLALVSGALRSYLKDRGELPAKSLVSQVP MLBr_01244|M.leprae_Br4923 IQLSDLHKAAKAG-DGSINDAYLAGLVGALRRYHEALG-VSISTLPMAVP : * : . .:**. :* *. * . ..* :* MMAR_3330|M.marinum_M VSVR--TGERQYGNQISSMIVPIPTDQADARTRLISAHQVMRAAKERHRA MUL_1313|M.ulcerans_Agy99 VSVR--TGERQYGNQISSMIVPIPTDQADARARLISAHQVMRAAKERHRA MSMEG_4297|M.smegmatis_MC2_155 VSVH-DRSDRPGRNQVSGMFSPLQTHIADPAERLRAIAEANAVAKQHSSA Mvan_3601|M.vanbaalenii_PYR-1 VSVH-DKSDRPGRNQVSGMFSRLETNIEDPATRLKAIAEANSVAKQHSSA TH_2477|M.thermoresistible__bu VSVH-DKTDRPGRNHVSGMFSRLETTIEDPAERLRAIANANSVAKQHSSA MAV_2240|M.avium_104 ISVH-GKSDRPGRNQVSAMFASLHTEIADPVQRLKAIAHANSLAKEHSSA Mb1460|M.bovis_AF2122/97 VSTRSEETKADVGNQVSSMTASLATHIEDPAKRLAAIHESTLSAKEMAKA Rv1425|M.tuberculosis_H37Rv VSTRSEETKADVGNQVSSMTASLATHIEDPAKRLAAIHESTLSAKEMAKA MAB_0507|M.abscessus_ATCC_1997 VSVRTEETDGVVGNQVSSMTVSLATDIDDPAERIQAIYEGTQGAKEMARA Mflv_0349|M.gilvum_PYR-GCK VSTR-AQADDTVGNQVNAMTVVLATDVADPAERIKAIYSYTQGAKEMTKA MLBr_01244|M.leprae_Br4923 VNVR-TEADVVGSNRFVGVTLAAPLGTNDPAARMQKIRSQMTQRRDEPAM :..: . *:. .: *. *: :: MMAR_3330|M.marinum_M IPAKLLTEANHTVPPALLTRAARVISMTTGSGWIRPPFNVTISNIPGSPD MUL_1313|M.ulcerans_Agy99 IPAKLLTEANHTVPPALLTRAARVISMTTGSGWIRPPFNVTISNIPGSPD MSMEG_4297|M.smegmatis_MC2_155 IGATLLQDWTQFAAPAVFGTAMRVYAASR-LSGAKPVHNLVVSNVPGPQV Mvan_3601|M.vanbaalenii_PYR-1 IAATLLQDWTQFAAPAVFGAAMRVYASSR-LSGARPVHNLVISNVPGPQG TH_2477|M.thermoresistible__bu IAASLLQDWTQFAAPAVFGVAMRVYAASR-LGEAKPVHNLVVSNVPGPQV MAV_2240|M.avium_104 IGASLLQDWTQFAAPAVFGIAMRLYARTR-FTDSMPVHNLVVSNVPGPQL Mb1460|M.bovis_AF2122/97 LSAHQIMGLTETTPPGLLQLAARAYTASG-LSHNLAPINLVVSNVPGPPF Rv1425|M.tuberculosis_H37Rv PSAHQIMGLTETTPPGLLQLAARAYTASG-LSHNLAPINLVVSNVPGPPF MAB_0507|M.abscessus_ATCC_1997 MSAHQIMGLTDTTPPGLLQLAARAYTASG-LSRNLAPINLVLSNVPGPSF Mflv_0349|M.gilvum_PYR-GCK LTAHQIMGYTETTPPGLLALASRAYAASG-IGSNIAPMNVVISNVPGPTF MLBr_01244|M.leprae_Br4923 NIIGSLAPLMTVLPASVLDFIVDSVASSD----------VNASNIPAYPG : ...:: : : : **:*. MMAR_3330|M.marinum_M PLYCAGARVVSQHPVNVLLDGMGLSITLLSYQDRLDFGLTADRELLPDVW MUL_1313|M.ulcerans_Agy99 PLYCAGARVVSQHPVNVLLDGMGLSITLLSYQDRLDFGLTADRELLPDVW MSMEG_4297|M.smegmatis_MC2_155 PLYFLGAEVKAMYPLGPIFHGSGLNITVMSLTGKLDVGIISCPELLPDLW Mvan_3601|M.vanbaalenii_PYR-1 PLYMLGCEVKAMYPLGPIFHGSGLNMTVMSLSGKLDVGIVSCPELLPDLW TH_2477|M.thermoresistible__bu PLYFLGAEVKAMYPLGPIFHGSGLNITVMSLTGRLNVGMVSCPELMPDLW MAV_2240|M.avium_104 PLYLLGCEVKAMYPLGPIFHGSGLNITAMSLRGKLDVGLIGCPDLVPDLW Mb1460|M.bovis_AF2122/97 PLYMAGARLDSLVPLGPPVMDVALNITCFSYQDYLDFGLVTTPEVANDID Rv1425|M.tuberculosis_H37Rv PLYMAGARLDSLVPLGPPVMDVALNITCFSYQDYLDFGLVTTPEVANDID MAB_0507|M.abscessus_ATCC_1997 PLYMAGARLESMIPLGPPVMDVALNITCFSYLEHMDFGFVTTPEVAADID Mflv_0349|M.gilvum_PYR-GCK PLYLGGARVEHLMPVGPLLFDVALNVTCFSYCGAVDFGFITTPEIAADIV MLBr_01244|M.leprae_Br4923 DTYFAGAKILRQYGIGP-RPGVAMMAVLMSRGGFCTVTVRYDRASVKSEA * *..: :. . .: . :* . . . MMAR_3330|M.marinum_M HLADELAAELSALAAEVGAPRNPVADGAPTGTTGRPTAKPGAIPR MUL_1313|M.ulcerans_Agy99 HLADELAAELSALAAEVGAPRNPVADGAPTSTTGRPTAKPGAIPR MSMEG_4297|M.smegmatis_MC2_155 DMADDFAVALDELLDATKRA------------------------- Mvan_3601|M.vanbaalenii_PYR-1 DMADTFGVALQELLDATR--------------------------- TH_2477|M.thermoresistible__bu ELAEGFERALRELLDTVG--------------------------- MAV_2240|M.avium_104 ELADEFAVAMEELRAAAR--------------------------- Mb1460|M.bovis_AF2122/97 EMADAIEPALAELERAAE--------------------------- Rv1425|M.tuberculosis_H37Rv EMADAIEPALAELERAAE--------------------------- MAB_0507|M.abscessus_ATCC_1997 EMADGLEAALVELEHAVGI-------------------------- Mflv_0349|M.gilvum_PYR-GCK DLADQIEPALHDLEVAAGLVSDPTRPKPRKRGRR----------- MLBr_01244|M.leprae_Br4923 LFARCLLEGFDEVLALAGDPTPHAVPASFAARSSGSPAGWLSSS- :* : : : .