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SEHTGRRVERSLASSATERAGCTDRHGVASSFARNEQLDARRRAVLSRRVRMLVGATIGYKVIAAIVGVA AGEVASSTALIGFGLDSVIEVASALAVGWQFFGKHPEARERLALKGIAVSFFALAAYITVESVRSLQGGD EAEHSTTGIVLAAVSLLVMPLLFHAKQRVGQELGSASVVADSRQSLLCIYLSGILLVGLLLNSLFGFSWA DHVVALIIAGAAVKEGRQAWRGQHCC*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2136 | - | - | 100% (237) | metal transport protein |
| M. marinum M | MMAR_1270 | - | 5e-25 | 36.13% (191) | hypothetical protein MMAR_1270 |
| M. marinum M | MMAR_3313 | - | 2e-12 | 28.71% (202) | hypothetical protein MMAR_3313 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3299c | - | 1e-26 | 35.60% (191) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_3901 | - | 4e-76 | 63.29% (237) | Co/Zn/Cd cation transporters-like protein |
| M. tuberculosis H37Rv | Rv3271c | - | 1e-26 | 35.60% (191) | integral membrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2603c | - | 2e-65 | 63.32% (199) | integral membrane protein |
| M. avium 104 | MAV_3555 | - | 3e-10 | 27.87% (183) | cation efflux family protein |
| M. smegmatis MC2 155 | MSMEG_5604 | - | 5e-68 | 61.27% (204) | integral membrane protein |
| M. thermoresistible (build 8) | TH_1241 | - | 5e-66 | 61.81% (199) | integral membrane protein |
| M. ulcerans Agy99 | MUL_2617 | - | 3e-25 | 36.13% (191) | hypothetical protein MUL_2617 |
| M. vanbaalenii PYR-1 | Mvan_3938 | - | 2e-59 | 58.79% (199) | cation efflux protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3299c|M.bovis_AF2122/97 --------METTT-----------EHRDESTLDSPVSVAREAEWQRNVRW
Rv3271c|M.tuberculosis_H37Rv --------METTT-----------EHRDESTLDSPVSVAREAEWQRNVRW
MUL_2617|M.ulcerans_Agy99 --------MNTSSSVGKVGDLAGDACCDVSTTAAHTGHSGDAAWQQGVRW
MMAR_2136|M.marinum_M MSEHTGRRVERSLASSATERAGCTDRHGVASSFARNEQLDARRRAVLSRR
Mflv_3901|M.gilvum_PYR-GCK MTDPAAEELKPLIASS----AGCTD----AGCTATAATVSPARRAVLTRR
MAB_2603c|M.abscessus_ATCC_199 ------------------------------------MVLAQQRRDVLNRR
Mvan_3938|M.vanbaalenii_PYR-1 ------------------------------------MALTAERRSVLTRR
MSMEG_5604|M.smegmatis_MC2_155 MRRPRWRRVRMRMMAD-------------------TSKLTPTRRAVLARR
TH_1241|M.thermoresistible__bu --------VTPSGAIG-------------------WRPLSESRRQQLARR
MAV_3555|M.avium_104 --------MHVINGVR--------------DPAASFPLDTATDDAGERRQ
*
Mb3299c|M.bovis_AF2122/97 ARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEGLASAMVLW
Rv3271c|M.tuberculosis_H37Rv ARWLAWVSLAVLLTEGAVGLWQGIAVGSVALTGWALGGGSEGLASAMVLW
MUL_2617|M.ulcerans_Agy99 ARRLAWISLAVLVTEGAVGVWEGVAVGSVALTGWALGGASEGLASAMVLW
MMAR_2136|M.marinum_M VRMLVGATIGYKVIAAIVGVAAGEVASSTALIGFGLDSVIEVASALAVGW
Mflv_3901|M.gilvum_PYR-GCK VRLFVLATITYNLIEAVVAISAGTIASSAALIGFGLDSLIEVASATAVAW
MAB_2603c|M.abscessus_ATCC_199 IRFFVVATIAYNVIEAIVALTEGSRVSSTALIGFGLDSVIEVSSAAAVAW
Mvan_3938|M.vanbaalenii_PYR-1 IRFLVAATITYNVIEAVVALAEGSRVSSAALVGFGLDSVVEVSSAAAVAW
MSMEG_5604|M.smegmatis_MC2_155 IRMFVAATITYNVIEAVVALTEGARVSSTALIGFGLDSVIEVSSAAAVAW
TH_1241|M.thermoresistible__bu IRVLVAATISYNIIEAVVAIGEGARVSSTALIGFGLDSAIEVSSAAAVAW
MAV_3555|M.avium_104 ANRAVAVSAAGLALTGLVELVIAVVSGSVALLGDALHNLSDVSTSALVFV
. . : . * : . .*.** * .* . : :: *
Mb3299c|M.bovis_AF2122/97 RFTGDRTW--------SATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGE
Rv3271c|M.tuberculosis_H37Rv RFTGDRTW--------SATAEHRAQRGVAVSFWLTAPYLVAESIRHLAGE
MUL_2617|M.ulcerans_Agy99 RFTGSRTL--------SETAERRAQRGVAVSFWLVAPLVAAESIRHLTDK
MMAR_2136|M.marinum_M QFFGKH----------PEARERLALKGIAVSFFALAAYITVESVRSLQGG
Mflv_3901|M.gilvum_PYR-GCK QFAGRD----------PEERERTALRIIAVSFFALATYVTVESARALFGA
MAB_2603c|M.abscessus_ATCC_199 QFSAKD----------PETREKVALRVIAFSFFALAAYVAVDSVRALAGL
Mvan_3938|M.vanbaalenii_PYR-1 QFSAVD----------PETREKAALRFIAFSFFALACYVAVDAALSLVGV
MSMEG_5604|M.smegmatis_MC2_155 QFAGRD----------PEAREKVALRIVAFSFFGLATYVAVDAIRSLLGI
TH_1241|M.thermoresistible__bu QFAGRD----------PEARERIALRVIAFSFFGLATFVTVDAVRALLGM
MAV_3555|M.avium_104 GFRASRKLPTERYPYGYERAEDLAGIGVALVIWGSAVVAGFESVTKLLRH
* . * * :*. :: * :: *
Mb3299c|M.bovis_AF2122/97 HRAETSVIGIGLTAIALLLMPVLGWANHRVGERLGSGATAGEGTQNYLCA
Rv3271c|M.tuberculosis_H37Rv HRAETSVIGIGLTAIALLLMPVLGWANHRVGERLGSGATAGEGTQNYLCA
MUL_2617|M.ulcerans_Agy99 HEVGTSVIGIGLTAFALVVMPILGRANHKLGVLLQSGATEGEGTQNYLCA
MMAR_2136|M.marinum_M DEAEHSTTGIVLAAVSLLVMPLLFHAKQRVGQELGSASVVADSRQSLLCI
Mflv_3901|M.gilvum_PYR-GCK AEAAPSPAGIVLAAVSLAVMPFLSYAQRRAGRELGSASAVADSKQTLLCT
MAB_2603c|M.abscessus_ATCC_199 DQARQSTVGIALAAASLVIMPALSWAQRRTGRELGSASAVADSKQTLLCT
Mvan_3938|M.vanbaalenii_PYR-1 REPRPTPIGIVLAGLSLAVMPTLSLAQRRAGRELGSRSAVADSKQTLLCA
MSMEG_5604|M.smegmatis_MC2_155 GEAQHSTIGIALAALSLVIMPVLSYAQRRAGRELGSLSAVADSKQTLLCT
TH_1241|M.thermoresistible__bu GESRPSTVGIVVAALSLLIMPVLSYAQRRAGRELGSLSAVADSKQTLLCT
MAV_3555|M.avium_104 GGTGHVGWGIAAAVVGVVGNQLVARYKLVVGRRIRSATMVADAKHSWLDA
** : .: : : * : * : .:. :. *
Mb3299c|M.bovis_AF2122/97 AQAAAVLLGLAITAVWSNGWWIDPAIGLAIAGIAVWQGIRT---------
Rv3271c|M.tuberculosis_H37Rv AQAAAVLLGLAITAVWSNGWWIDPAIGLAIAGIAVWQGIRT---------
MUL_2617|M.ulcerans_Agy99 GQAAGVLLGLAITAAWPGGWWIDPGIGLVIAGIAVWQGVRA---------
MMAR_2136|M.marinum_M YLSGILLVGLLLNSLFG-FSWADHVVALIIAGAAVKEGRQA---------
Mflv_3901|M.gilvum_PYR-GCK YLSGVLLVGLLLNALFG-WSWADPIVALVIAGVAVKEGRQA---------
MAB_2603c|M.abscessus_ATCC_199 YLSAVLLAGLLVNSLFA-WSWADPIAALAIAVIAVREGMNA---------
Mvan_3938|M.vanbaalenii_PYR-1 YLSAVLLVGLVLHALLG-WTWADPVAALGIAALAVREGLEA---------
MSMEG_5604|M.smegmatis_MC2_155 YLSAVLLVGLLLNSIFG-WSWADPIAGLVIAAVAVREGLEA---------
TH_1241|M.thermoresistible__bu YLSAVLLIGLLLNSLFG-WSWADPVAGLAIAAMAVREGIEA---------
MAV_3555|M.avium_104 LSSAGAVLGLIG-VALG-WGWADAVAGIVVTGFICHVGWEVTADIAHRLL
:. : ** * * .: :: * ..
Mb3299c|M.bovis_AF2122/97 -----------------------------WRGHGCGC-------------
Rv3271c|M.tuberculosis_H37Rv -----------------------------WRGHGCGC-------------
MUL_2617|M.ulcerans_Agy99 -----------------------------WRGQDCGC-------------
MMAR_2136|M.marinum_M -----------------------------WRGQHCC--------------
Mflv_3901|M.gilvum_PYR-GCK -----------------------------WRGEHCC--------------
MAB_2603c|M.abscessus_ATCC_199 -----------------------------WRGESCCMPVFAAGASELTGS
Mvan_3938|M.vanbaalenii_PYR-1 -----------------------------WRGDPCCR-------------
MSMEG_5604|M.smegmatis_MC2_155 -----------------------------WKGDTCCSAG-----------
TH_1241|M.thermoresistible__bu -----------------------------WRGDTCCAVPVGT-SRTATES
MAV_3555|M.avium_104 DGVDPDIVTTAEAVAVSVPGVTHAHARARWTGRTLRVEVEGFLDAATSLS
* *
Mb3299c|M.bovis_AF2122/97 ------------------------------
Rv3271c|M.tuberculosis_H37Rv ------------------------------
MUL_2617|M.ulcerans_Agy99 ------------------------------
MMAR_2136|M.marinum_M ------------------------------
Mflv_3901|M.gilvum_PYR-GCK ------------------------------
MAB_2603c|M.abscessus_ATCC_199 QCGCCERRAP--------------------
Mvan_3938|M.vanbaalenii_PYR-1 ------------------------------
MSMEG_5604|M.smegmatis_MC2_155 ------------------------------
TH_1241|M.thermoresistible__bu GCGCGDDRE---------------------
MAV_3555|M.avium_104 DSDRIGRSVAAALAPRLPQMQSFTWTARAA