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VRYGCGRDVVVNAGAAHAHAQASADSDRRWLLGALAVIVAFMIGEVTVGVVASSLALISDAAHMLTDAAS IALALWAIRLAARPAAGRMTYGWKRAEILSAQANGLTLLLLAAWLADEAIRRLIHPPQVTGTLVLITALV GIAVNVAATCMISRANRTSLNVEGAFQHILNDLFAFIATAVAGLIILLTGFSRADAIATLVVVALMVKAG FELVGASSRIFMEAAPKDLDPAVVGQAMAAREAVVEVHDLHIWEITSGSPALSAHVLIEAGRDCHAVRSD LARLLAERHHIHHTTLQVDHVDVIDRGEPNNGPHCEEPHGPAHRSNDIH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2137 | - | - | 100% (329) | metal transport protein |
| M. marinum M | MMAR_2144 | - | 8e-53 | 39.19% (296) | hypothetical protein MMAR_2144 |
| M. marinum M | MMAR_0677 | - | 5e-42 | 31.72% (290) | efflux membrane protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2050c | - | 3e-13 | 29.25% (294) | hypothetical protein Mb2050c |
| M. gilvum PYR-GCK | Mflv_0231 | - | 3e-43 | 32.41% (290) | cation diffusion facilitator family transporter |
| M. tuberculosis H37Rv | Rv2025c | - | 3e-13 | 29.25% (294) | hypothetical protein Rv2025c |
| M. leprae Br4923 | MLBr_00283 | - | 1e-25 | 27.16% (232) | putative cation-efflux transporter component |
| M. abscessus ATCC 19977 | MAB_0183c | - | 1e-105 | 62.74% (314) | putative cation transporter |
| M. avium 104 | MAV_4782 | - | 5e-40 | 31.16% (292) | cobalt-zinc-cadmium resistance protein |
| M. smegmatis MC2 155 | MSMEG_0755 | - | 5e-43 | 32.76% (290) | cobalt-zinc-cadmium resistance protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_2837 | - | 3e-42 | 31.72% (290) | efflux membrane protein |
| M. vanbaalenii PYR-1 | Mvan_0673 | - | 1e-42 | 32.41% (290) | cation diffusion facilitator family transporter |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2137|M.marinum_M ------MRYGCGRDVVVN-AGAAHAHAQASADSDRR------WLLGALAV
MAB_0183c|M.abscessus_ATCC_199 ----------MAADAHEHGSGHSHGHG-VNADADRK------WLTIALIL
MAV_4782|M.avium_104 -----------------MGAGHNHTPAETGDARLIP------RMVMAAAI
MUL_2837|M.ulcerans_Agy99 -----------------MGAGHNHTPATAYASRMIP------RMVCAATI
Mflv_0231|M.gilvum_PYR-GCK ----------MRIYFWPMGAGHDHSHGGG--DTKVS------RMVIAAGI
Mvan_0673|M.vanbaalenii_PYR-1 -----------------MGAGHDHSHGG---DTKVS------RMVLGAAI
MSMEG_0755|M.smegmatis_MC2_155 -----------------MGAGHDHSHHT---DARVS------RMLVAAAI
MLBr_00283|M.leprae_Br4923 -----MQCMRKHAYIAHMGSGGSYTPAEAAIYRMIR------RMIVAAAI
Mb2050c|M.bovis_AF2122/97 MTHDHAHSRGVPAMIKEIFAPHSHDAADSVDDTLESTAAGIRTVKISLLV
Rv2025c|M.tuberculosis_H37Rv MTHDHAHSRGVPAMIKEIFAPHSHDAADSVDDTLESTAAGIRTVKISLLV
: : : . :
MMAR_2137|M.marinum_M IVAFMIGEVTVGVVASSLALISDAAHMLTDAASIALALWAIRLAARPAAG
MAB_0183c|M.abscessus_ATCC_199 IGGFMAIEVVIGIIAQSLALISDAGHMLTDAASIVLALIAIRLSSRPARG
MAV_4782|M.avium_104 LAAFFVVELVTSLLINSIALLADAGHMLTDVVAVFMGLAAVTLARRGSSS
MUL_2837|M.ulcerans_Agy99 LAMFFVVELTTAWLINSIALLADAGHMLTDVVAVFMGLAAVILGRRGSSS
Mflv_0231|M.gilvum_PYR-GCK LTIFFVVELTTALAINSIALLADAGHMLTDLVSMFMGLTAVLLAKRGSAS
Mvan_0673|M.vanbaalenii_PYR-1 LTVFFIVELSTALAINSIALLADAGHMLTDLVAMFMGLTAVLLARRGSTS
MSMEG_0755|M.smegmatis_MC2_155 LTAFFFVELITALMINSIALLADAGHMLTDLVAMFMGLTAVLLARRGSTS
MLBr_00283|M.leprae_Br4923 LMVFFGVELTIALLINSITLLADAGHMLTDVVAVFMGLAALVLAKHGHSA
Mb2050c|M.bovis_AF2122/97 LGLTALIQIVIVVMSGSVALAADTIHNFADALTAVPLWIAFALGAKPATR
Rv2025c|M.tuberculosis_H37Rv LGLTALIQIVIVVMSGSVALAADTIHNFADALTAVPLWIAFALGAKPATR
: :: *::* :*: * ::* : *. *. :
MMAR_2137|M.marinum_M -RMTYGWKRAEILSAQANGLTLLLLAAWLADEAIRRLIHPPQVTGT-LVL
MAB_0183c|M.abscessus_ATCC_199 -SYTFGLKRAEILSAQANGVTLFLLAAFFIYEGIRRLITPPEVSGL-LVF
MAV_4782|M.avium_104 PARTYGWHRAEVFTAVANAGLLIGVSVFILYEAIQRLREAPAVPGV-PMI
MUL_2837|M.ulcerans_Agy99 PNRTYGWHRAEVFTAVANAALLIGVALFIVYEAIDRLREAPSVPGL-PMI
Mflv_0231|M.gilvum_PYR-GCK PSRTYGWHRAEVFTAVANAALLLGVAGFILYEAVERLGDAPDVPGV-PMI
Mvan_0673|M.vanbaalenii_PYR-1 PSRTYGWHRAEVFTAVANAALLFGVAGFILYEAFERLGDAPDVPGV-PMI
MSMEG_0755|M.smegmatis_MC2_155 PARTFGWHRAEVFTAVANAALLIGVAGFILYEAFERLGNAPEVPGV-PMI
MLBr_00283|M.leprae_Br4923 PNRPYSWHRAEVFTAMANAALLIGVATFILYEAIRRFKEAPYIPGM-PIV
Mb2050c|M.bovis_AF2122/97 -RYTYGFGRVEDLAGSFVVAMITMSAIIAGYEAIARLIHPQQIEHVGWVA
Rv2025c|M.tuberculosis_H37Rv -RYTYGFGRVEDLAGSFVVAMITMSAIIAGYEAIARLIHPQQIEHVGWVA
.:. *.* ::. : : *.. *: . : :
MMAR_2137|M.marinum_M ITALVGIAVNVAATCMISRANR--TSLNVEGAFQHILNDLFAFIATAVAG
MAB_0183c|M.abscessus_ATCC_199 ITALAGIAVNVAATWCISKANR--SSLNVEGAFQHILNDLYAFIATAVAG
MAV_4782|M.avium_104 VVALAGLAANFVVALLLRSHSS--GSLAVKGAYLEVIADTVGSLGVLIAG
MUL_2837|M.ulcerans_Agy99 VVALAGLSANIVVALLLRSHAD--SSLAVKGAYMEVVADTVGSLGVLAAG
Mflv_0231|M.gilvum_PYR-GCK VVALAGLLANLIVVLLLRSHSK--ESLAVKGAYMEVVADTVGSIGVLIAG
Mvan_0673|M.vanbaalenii_PYR-1 VVALAGLLANAVVVLLLRSHSK--ESLAVKGAYMEVVADTVGSIGVLIAG
MSMEG_0755|M.smegmatis_MC2_155 VVALAGLIANAAVVLMLRSHSK--DSLAVKGAYMEVVADTVGSIGVLIAG
MLBr_00283|M.leprae_Br4923 VAALAGLVTNFVVAPLLRPHAE--DSLAIKGAYMEAVADTVGNIGVLIAG
Mb2050c|M.bovis_AF2122/97 LAGLVGFIGNEWVALYRIRVGHRIGSAALIADGLHARTDGFTSLAVLCS-
Rv2025c|M.tuberculosis_H37Rv LAGLVGFIGNEWVALYRIRVGHRIGSAALIADGLHARTDGFTSLAVLCS-
:..*.*: * .. * : . . * :.. :
MMAR_2137|M.marinum_M LIILLTGFSRADAIATLVVVALMVKAGFELVGASSRIFMEAAPKDLDPAV
MAB_0183c|M.abscessus_ATCC_199 AVVWLTGFTRADAIAALVVAALMLKAGWGLVRESGRIFLEAAPVGLDPGT
MAV_4782|M.avium_104 VVTVTTRWPYADVVVAVLVALWVLPRAISLARDALRILSESSPTHIDVEE
MUL_2837|M.ulcerans_Agy99 VVTVTTSWPYADVVVAVLVALWVAPRAVSLARAALRILSESSPRHIDVDE
Mflv_0231|M.gilvum_PYR-GCK IVTVTTAWPYADVVVAVLVALWVLPRAIALARAALRILSESSPAHIDVDE
Mvan_0673|M.vanbaalenii_PYR-1 IVTVTTRWPYADVVVAVLVALWVLPRAISLARAALRILSESSPRHIDVEE
MSMEG_0755|M.smegmatis_MC2_155 IVTVTTGWPYADVVVAVLVALWVLPRAIALARAALRILSESSPAHIDVEK
MLBr_00283|M.leprae_Br4923 VVTLTTHWPYADVVVAVLVALWVLPRAISLARAACGSFPNCRRPTIDVEA
Mb2050c|M.bovis_AF2122/97 AGGVALGFPLADPIVGLLITAAILAVLRTAARDVFRRLLDG-VDPAMVDA
Rv2025c|M.tuberculosis_H37Rv AGGVALGFPLADPIVGLLITAAILAVLRTAARDVFRRLLDG-VDPAMVDA
:. ** :. :::. : . : :
MMAR_2137|M.marinum_M VGQAMAAREAVVEVHDLHIWEITSGSPALSAHVLIEAGRDCHAVRSDLAR
MAB_0183c|M.abscessus_ATCC_199 IGTQLAAVHAVAEVHDLHIWQITSGQPALSAHILVAPNADCHGIRREIEE
MAV_4782|M.avium_104 LRAALGAVDGVTGVHDLHVWTLSPGKDMCTAHLISTG---DSARVLRDAR
MUL_2837|M.ulcerans_Agy99 LRSALRAVDGVTEVHDLHVWTLAPGKDMATAHLTSSA---DSARVLHDAR
Mflv_0231|M.gilvum_PYR-GCK LRDALCAVDGVTEVHDLHVWTLVPGKDMVTAHLTSVR---ESAAVLDDAR
Mvan_0673|M.vanbaalenii_PYR-1 LRAALGAVDGVTEVHDLHVWTLVPGKDMVTAHLTSDR---DSAQILDDAR
MSMEG_0755|M.smegmatis_MC2_155 LRSALCAVDGVTDVHDLHVWTLVPGKDMVTAHLTSDA---DTARVLDDAR
MLBr_00283|M.leprae_Br4923 LRSALGRRR--------------------------------------RHR
Mb2050c|M.bovis_AF2122/97 AEQALAARPGVQAVRSVRMRWIGHRLHADAELDVDPALDLAQAHRIAHDA
Rv2025c|M.tuberculosis_H37Rv AEQALAARPGVQAVRSVRMRWIGHRLHADAELDVDPALDLAQAHRIAHDA
:
MMAR_2137|M.marinum_M LLAERHHIHHTTLQVDHVDVIDRGEPNNGPHCEEPHGPAHRSNDIH----
MAB_0183c|M.abscessus_ATCC_199 LLHTQYDIDHTTLQVDHEGTEAS------THCFDPHGEPYRADGSALPGK
MAV_4782|M.avium_104 AVLSARGLAHATVQIDCPDDT-ECSDSF----------------------
MUL_2837|M.ulcerans_Agy99 AVLSDRGLHHATVQIEHTAGIQECPDSCSDAVPAIG--------------
Mflv_0231|M.gilvum_PYR-GCK AVLTARGLGHATVQVEPPDSAADCECETEKR-------------------
Mvan_0673|M.vanbaalenii_PYR-1 AVLAARGLDHSTVQVEPPDTAADCECESRKR-------------------
MSMEG_0755|M.smegmatis_MC2_155 AVLTAHGLEHATVQVEPPDAAGDCRCEAE---------------------
MLBr_00283|M.leprae_Br4923 SARPARVNTFARRRYVPPRT------------------------------
Mb2050c|M.bovis_AF2122/97 EHELTHTVPKLTTALIHAYPAEHGSSIPDRGRTVE---------------
Rv2025c|M.tuberculosis_H37Rv EHELTHTVPKLTTALIHAYPAEHGSSIPDRGRTVE---------------
MMAR_2137|M.marinum_M -
MAB_0183c|M.abscessus_ATCC_199 G
MAV_4782|M.avium_104 -
MUL_2837|M.ulcerans_Agy99 -
Mflv_0231|M.gilvum_PYR-GCK -
Mvan_0673|M.vanbaalenii_PYR-1 -
MSMEG_0755|M.smegmatis_MC2_155 -
MLBr_00283|M.leprae_Br4923 -
Mb2050c|M.bovis_AF2122/97 -
Rv2025c|M.tuberculosis_H37Rv -