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LTVDFDRLGIGPGATVIDVGCGAGRHAFEAYRCGADVVAFDRDAAELRAVDTMLRAMAQTGEAPAAASAK VVLGDALALPYPDGTFDCVIASEILEHVPQDDAAIAELVRVLKVGGTLAISVPRWLPERVCWLLSDEYHS NEGGHVRVYRASELREKITRHPMALTHAHHAHALHSPFWWLKCAVGVSNADHPLVSAYHKLLVWDLMRRP RVTRMAESVLNPLVGKSVAMYFDKRESAQSPADLGHSVASA*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_2924 | - | - | 100% (252) | SAM-dependent methyltransferase |
M. marinum M | MMAR_2214 | - | 6e-11 | 35.77% (123) | methyltransferase |
M. marinum M | MMAR_1062 | - | 1e-09 | 37.38% (107) | methyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1440c | - | 1e-10 | 33.93% (112) | putative methyltransferase |
M. gilvum PYR-GCK | Mflv_1100 | - | 1e-103 | 71.49% (235) | methyltransferase type 11 |
M. tuberculosis H37Rv | Rv1405c | - | 1e-10 | 33.93% (112) | putative methyltransferase |
M. leprae Br4923 | MLBr_00551 | - | 1e-09 | 33.04% (112) | putative methyltransferase |
M. abscessus ATCC 19977 | MAB_4481 | - | 2e-08 | 31.58% (114) | hypothetical protein MAB_4481 |
M. avium 104 | MAV_2756 | - | 1e-120 | 81.27% (251) | methyltransferase |
M. smegmatis MC2 155 | MSMEG_6483 | - | 1e-103 | 70.17% (238) | methyltransferase type 11 |
M. thermoresistible (build 8) | TH_0087 | - | 1e-106 | 75.31% (239) | methyltransferase type 11 |
M. ulcerans Agy99 | MUL_1801 | - | 4e-11 | 35.77% (123) | methyltransferase |
M. vanbaalenii PYR-1 | Mvan_5717 | - | 1e-103 | 70.54% (241) | methyltransferase type 11 |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_2924|M.marinum_M ---------------------------------------------MLTVD MAV_2756|M.avium_104 ---------------------------------------------MLTVD Mflv_1100|M.gilvum_PYR-GCK ---------------------------------------------MLTVD Mvan_5717|M.vanbaalenii_PYR-1 ---------------------------------------------MLTVD MSMEG_6483|M.smegmatis_MC2_155 ---------------------------------------------MLTVD TH_0087|M.thermoresistible__bu ---------------------------------------------MLTVD Mb1440c|M.bovis_AF2122/97 -------MTIDTPAREDQTLAATHRAMWALGD--YALMAEEVMAPLGPIL Rv1405c|M.tuberculosis_H37Rv -------MTIDTPAREDQTLAATHRAMWALGD--YALMAEEVMAPLGPIL MUL_1801|M.ulcerans_Agy99 -------MTIDTPIREDVSLAATHRAMWALGD--YALMAEEVMAPLGPIL MLBr_00551|M.leprae_Br4923 -------MNLYTPIHEDQSLAAIHRAMWALGD--YALMAEEVMAPLGPIL MAB_4481|M.abscessus_ATCC_1997 MPDITDLFAQRATLRRSTSLLTAFRFEQSAPERFYGTLAQDTVHLITDLW : : MMAR_2924|M.marinum_M FDRLGIGP-GATVIDVGCGAGRHAFEAYRCGADVVAFDRDAAELRAVDTM MAV_2756|M.avium_104 FDRLGIGP-SSKVIDVGCGAGRHAFEAYRRGADVVAFDQNEAELRSVDTV Mflv_1100|M.gilvum_PYR-GCK FDRLGVGA-GTKVIDVGCGAGRHTFEAFRRGADVIGFDQSASDLNDVDEI Mvan_5717|M.vanbaalenii_PYR-1 FDRLGVGA-GTKVIDVGCGAGRHTFEAFRRGADVVGFDQSVSDLNDVDEI MSMEG_6483|M.smegmatis_MC2_155 FDRLGVGP-GTSVIDVGCGAGRHTFEAFRRGAHVIGFDQNVADLNSVDEM TH_0087|M.thermoresistible__bu YDRLGIGP-GVSVIDVGCGLGRHSFEAYRRGAHIVAFDQNAEELNEVDTI Mb1440c|M.bovis_AF2122/97 VAAAGIGP-GVRVLDVAAGSGNISLPAAKTGATVISTD--------LTPE Rv1405c|M.tuberculosis_H37Rv VAAAGIGP-GVRVLDVAAGSGNISLPAAKTGATVISTD--------LTPE MUL_1801|M.ulcerans_Agy99 VAAAGIGP-GVRVLDVAAGSGNISLPAAKSGATVVSTD--------LTSE MLBr_00551|M.leprae_Br4923 VTATGIRP-GMQVLDVAAGSGNISLPAAKTGATIVSTD--------LTPE MAB_4481|M.abscessus_ATCC_1997 QQAEGVALRGRTVLDVGGGPGYFASAFADAGARYIGVEPD-------PRE *: . *:**. * * : ** :. : MMAR_2924|M.marinum_M LRAMAQTGEAPAAASAKVVLGDALALPYPDGTFDCVIASEILEHVPQDDA MAV_2756|M.avium_104 LRAMADSGEAPAGASATVVVGDALKLPYPDQTFDCVIASEILEHIPHDDA Mflv_1100|M.gilvum_PYR-GCK LQAMKEQGEAPASAKGEAVKGDALELPYADGTFDCVIASEILEHVPADDK Mvan_5717|M.vanbaalenii_PYR-1 LQAMKEQGEVPASAKGEAVKGDALDLPYADGTFDCVIASEILEHVPEDDR MSMEG_6483|M.smegmatis_MC2_155 LQAMAEAGEAPATAKGEAVKGDALDLPYEDGTFDCVIASEILEHVPEDDR TH_0087|M.thermoresistible__bu LQAMAEQREAPAGARAEVVKGDALDLPYADGTFDRVIASEILEHVPEDDR Mb1440c|M.bovis_AF2122/97 LLQRSQARAAQQGLTLQYQEANAQALPFADDEFDTVISAIGVMFAPDHQA Rv1405c|M.tuberculosis_H37Rv LLQRSQARAAQQGLTLQYQEANAQALPFADDEFDTVISAIGVMFAPDHQA MUL_1801|M.ulcerans_Agy99 LLQRSKARAAAQELTLDYQEANAQALPFGDSEFDTVISAIGVMFAPDHQC MLBr_00551|M.leprae_Br4923 LLQRSQARATELGLTLEYREADAQALPFGDGEFDVVMSAIGVMFAPDHRR MAB_4481|M.abscessus_ATCC_1997 MHAAPQGHRGIQDPRTTYLRASGMALPLADNSVDICLSSNVAEHVPQPWR : . ... ** * .* ::: . * MMAR_2924|M.marinum_M AIAELVRVLKVGGTLAISVPRWLPERVC---WLLSDEYHSNEGGHVR--- MAV_2756|M.avium_104 AIAELIRVLKVGGTLAVSVPRWLPERVC---WLLSDEYHSNEGGHVR--- Mflv_1100|M.gilvum_PYR-GCK AISELVRVLKPGGALAITVPRWLPERIC---WALSDEYHANEGGHIR--- Mvan_5717|M.vanbaalenii_PYR-1 AIAELVRVLKPGGALAITVPRWLPERIC---WALSDEYHANEGGHIR--- MSMEG_6483|M.smegmatis_MC2_155 AISELVRVLKPGGSLAITVPRWLPEKIC---WLLSDEYHANEGGHIR--- TH_0087|M.thermoresistible__bu AIAELVRVLKPGGKLVVTVPRWLPERIC---WLLSDEYHANEGGHVR--- Mb1440c|M.bovis_AF2122/97 AADELVRVCRPGG--TIGVISWTCEGFFGRMLATIRPYRPSVSADLPPSA Rv1405c|M.tuberculosis_H37Rv AADELVRVCRPGG--TIGVISWTCEGFFGRMLATIRPYRPSVSADLPPSA MUL_1801|M.ulcerans_Agy99 SANELARVCKTGG--TIGVISWTPEGFFGRMLATIRPYRPSLSAALPPSA MLBr_00551|M.leprae_Br4923 AASELVRVCRPNG--TIGVISWTQEGFFGRMLATIRPYRPSLSAALPPAA MAB_4481|M.abscessus_ATCC_1997 LGEEMLRVTRPGGLAILSYTVWLG------------PFGGHEMGLTH--- *: ** : .* : * : . MMAR_2924|M.marinum_M VYRASELREKITRHPMALTHAHHAHALHSPFWWLKCAVGVSNADH-PLVS MAV_2756|M.avium_104 IYRASDLRAKILSGGMTLTHAHHAHALHSPFWWLKCAVGVHNTDH-RAVA Mflv_1100|M.gilvum_PYR-GCK IYRADELRDKVLAHGLTLTHTHHSHALHSPFWWLKCAVGTEKNDH-PAVA Mvan_5717|M.vanbaalenii_PYR-1 IYRADELRDKVLAHGLALTHIHHAHALHSPYWWLKCAVGTEKTNH-PAVA MSMEG_6483|M.smegmatis_MC2_155 IYKADELRDKVLAHGLELTHTHHEHALHSPYWWLKCLVGTEKNDH-PAVK TH_0087|M.thermoresistible__bu IYRADELRDKITRHGLRLTHRHHAHALHSPFWWLKCAVGTNNDRH-FAVR Mb1440c|M.bovis_AF2122/97 LWGREAYVTGLLGDGVTGLKTARGLLEVKRFDTAQAVHDYFKNNYGPTIE Rv1405c|M.tuberculosis_H37Rv LWGREAYVTGLLGDGVTGLKTARGLLEVKRFDTAQAVHDYFKNNYGPTIE MUL_1801|M.ulcerans_Agy99 LWGREAYARGLFGNHVSDIQTQRGQLEVTRFQTAQAVHDYFKNHYGPTIE MLBr_00551|M.leprae_Br4923 LWGREAYIRGLLDDTVTNVKTERRQLEVKRFNSAEGVHNYFKNHYGPTIE MAB_4481|M.abscessus_ATCC_1997 YFGGARAARWYTRKHGHPPKNNYGSSLFPVSVRDGLRWARDTGTLTAAFP : : . . MMAR_2924|M.marinum_M AYHKLLVWDLMRRPRVTRMAESVLNPLVGKSVAMYFDKRESAQSPADLGH MAV_2756|M.avium_104 AYHKLLVWDLMRRPKITQLAESLLNPLVGKSVAMYFVKRQDAKSQATAGY Mflv_1100|M.gilvum_PYR-GCK AYHKLLVWDMMSQPWLTRTAEAALNPLIGKSVALYFRKPADTDA------ Mvan_5717|M.vanbaalenii_PYR-1 AYHKLLVWDMMGRPWLTRTAEAALNPLIGKSVALYFRKPAAADA------ MSMEG_6483|M.smegmatis_MC2_155 AYHQLLVWDMMGRPWLTRTAESALNPLIGKSVALYFTKPDARG------- TH_0087|M.thermoresistible__bu AYHQLLVWDMVRRPWVTRWAEEMLNPLIGKSVALYFDKPEVAGADS---- Mb1440c|M.bovis_AF2122/97 AYAHIGDNAVLAAELDRQLVELAAQYLSDGVMEWEYLLLTAEKR------ Rv1405c|M.tuberculosis_H37Rv AYAHIGDNAVLAAELDRQLVELAAQYLSDGVMEWEYLLLTAEKR------ MUL_1801|M.ulcerans_Agy99 AYANIGDNAVLAAELDAQLVELADQYLTDGVMEWEYLVLTGTKK------ MLBr_00551|M.leprae_Br4923 AYTNIGDNSVLAAELDAQLTELAQKYLTNSTMGWEYLLLTAQKH------ MAB_4481|M.abscessus_ATCC_1997 RYHPKWAWWITKIPALREVLVSNLVLVLRPR------------------- * : . : MMAR_2924|M.marinum_M SVASA MAV_2756|M.avium_104 SIASV Mflv_1100|M.gilvum_PYR-GCK ----- Mvan_5717|M.vanbaalenii_PYR-1 ----- MSMEG_6483|M.smegmatis_MC2_155 ----- TH_0087|M.thermoresistible__bu ----- Mb1440c|M.bovis_AF2122/97 ----- Rv1405c|M.tuberculosis_H37Rv ----- MUL_1801|M.ulcerans_Agy99 ----- MLBr_00551|M.leprae_Br4923 ----- MAB_4481|M.abscessus_ATCC_1997 -----