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M. marinum M MMAR_2924 (-)

annotation: SAM-dependent methyltransferase
coordinates: 3527466 - 3528224
length: 252

LTVDFDRLGIGPGATVIDVGCGAGRHAFEAYRCGADVVAFDRDAAELRAVDTMLRAMAQTGEAPAAASAK
VVLGDALALPYPDGTFDCVIASEILEHVPQDDAAIAELVRVLKVGGTLAISVPRWLPERVCWLLSDEYHS
NEGGHVRVYRASELREKITRHPMALTHAHHAHALHSPFWWLKCAVGVSNADHPLVSAYHKLLVWDLMRRP
RVTRMAESVLNPLVGKSVAMYFDKRESAQSPADLGHSVASA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_2924--100% (252)SAM-dependent methyltransferase
M. marinum MMMAR_2214-6e-1135.77% (123) methyltransferase
M. marinum MMMAR_1062-1e-0937.38% (107) methyltransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1440c-1e-1033.93% (112) putative methyltransferase
M. gilvum PYR-GCKMflv_1100-1e-10371.49% (235) methyltransferase type 11
M. tuberculosis H37RvRv1405c-1e-1033.93% (112) putative methyltransferase
M. leprae Br4923MLBr_00551-1e-0933.04% (112) putative methyltransferase
M. abscessus ATCC 19977MAB_4481-2e-0831.58% (114) hypothetical protein MAB_4481
M. avium 104MAV_2756-1e-12081.27% (251) methyltransferase
M. smegmatis MC2 155MSMEG_6483-1e-10370.17% (238) methyltransferase type 11
M. thermoresistible (build 8)TH_0087-1e-10675.31% (239) methyltransferase type 11
M. ulcerans Agy99MUL_1801-4e-1135.77% (123) methyltransferase
M. vanbaalenii PYR-1Mvan_5717-1e-10370.54% (241) methyltransferase type 11

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_2924|M.marinum_M               ---------------------------------------------MLTVD
MAV_2756|M.avium_104                ---------------------------------------------MLTVD
Mflv_1100|M.gilvum_PYR-GCK          ---------------------------------------------MLTVD
Mvan_5717|M.vanbaalenii_PYR-1       ---------------------------------------------MLTVD
MSMEG_6483|M.smegmatis_MC2_155      ---------------------------------------------MLTVD
TH_0087|M.thermoresistible__bu      ---------------------------------------------MLTVD
Mb1440c|M.bovis_AF2122/97           -------MTIDTPAREDQTLAATHRAMWALGD--YALMAEEVMAPLGPIL
Rv1405c|M.tuberculosis_H37Rv        -------MTIDTPAREDQTLAATHRAMWALGD--YALMAEEVMAPLGPIL
MUL_1801|M.ulcerans_Agy99           -------MTIDTPIREDVSLAATHRAMWALGD--YALMAEEVMAPLGPIL
MLBr_00551|M.leprae_Br4923          -------MNLYTPIHEDQSLAAIHRAMWALGD--YALMAEEVMAPLGPIL
MAB_4481|M.abscessus_ATCC_1997      MPDITDLFAQRATLRRSTSLLTAFRFEQSAPERFYGTLAQDTVHLITDLW
                                                                                 :  : 

MMAR_2924|M.marinum_M               FDRLGIGP-GATVIDVGCGAGRHAFEAYRCGADVVAFDRDAAELRAVDTM
MAV_2756|M.avium_104                FDRLGIGP-SSKVIDVGCGAGRHAFEAYRRGADVVAFDQNEAELRSVDTV
Mflv_1100|M.gilvum_PYR-GCK          FDRLGVGA-GTKVIDVGCGAGRHTFEAFRRGADVIGFDQSASDLNDVDEI
Mvan_5717|M.vanbaalenii_PYR-1       FDRLGVGA-GTKVIDVGCGAGRHTFEAFRRGADVVGFDQSVSDLNDVDEI
MSMEG_6483|M.smegmatis_MC2_155      FDRLGVGP-GTSVIDVGCGAGRHTFEAFRRGAHVIGFDQNVADLNSVDEM
TH_0087|M.thermoresistible__bu      YDRLGIGP-GVSVIDVGCGLGRHSFEAYRRGAHIVAFDQNAEELNEVDTI
Mb1440c|M.bovis_AF2122/97           VAAAGIGP-GVRVLDVAAGSGNISLPAAKTGATVISTD--------LTPE
Rv1405c|M.tuberculosis_H37Rv        VAAAGIGP-GVRVLDVAAGSGNISLPAAKTGATVISTD--------LTPE
MUL_1801|M.ulcerans_Agy99           VAAAGIGP-GVRVLDVAAGSGNISLPAAKSGATVVSTD--------LTSE
MLBr_00551|M.leprae_Br4923          VTATGIRP-GMQVLDVAAGSGNISLPAAKTGATIVSTD--------LTPE
MAB_4481|M.abscessus_ATCC_1997      QQAEGVALRGRTVLDVGGGPGYFASAFADAGARYIGVEPD-------PRE
                                        *:   .  *:**. * *  :      **  :. :            

MMAR_2924|M.marinum_M               LRAMAQTGEAPAAASAKVVLGDALALPYPDGTFDCVIASEILEHVPQDDA
MAV_2756|M.avium_104                LRAMADSGEAPAGASATVVVGDALKLPYPDQTFDCVIASEILEHIPHDDA
Mflv_1100|M.gilvum_PYR-GCK          LQAMKEQGEAPASAKGEAVKGDALELPYADGTFDCVIASEILEHVPADDK
Mvan_5717|M.vanbaalenii_PYR-1       LQAMKEQGEVPASAKGEAVKGDALDLPYADGTFDCVIASEILEHVPEDDR
MSMEG_6483|M.smegmatis_MC2_155      LQAMAEAGEAPATAKGEAVKGDALDLPYEDGTFDCVIASEILEHVPEDDR
TH_0087|M.thermoresistible__bu      LQAMAEQREAPAGARAEVVKGDALDLPYADGTFDRVIASEILEHVPEDDR
Mb1440c|M.bovis_AF2122/97           LLQRSQARAAQQGLTLQYQEANAQALPFADDEFDTVISAIGVMFAPDHQA
Rv1405c|M.tuberculosis_H37Rv        LLQRSQARAAQQGLTLQYQEANAQALPFADDEFDTVISAIGVMFAPDHQA
MUL_1801|M.ulcerans_Agy99           LLQRSKARAAAQELTLDYQEANAQALPFGDSEFDTVISAIGVMFAPDHQC
MLBr_00551|M.leprae_Br4923          LLQRSQARATELGLTLEYREADAQALPFGDGEFDVVMSAIGVMFAPDHRR
MAB_4481|M.abscessus_ATCC_1997      MHAAPQGHRGIQDPRTTYLRASGMALPLADNSVDICLSSNVAEHVPQPWR
                                    :    .              ...  **  *  .*  :::    . *    

MMAR_2924|M.marinum_M               AIAELVRVLKVGGTLAISVPRWLPERVC---WLLSDEYHSNEGGHVR---
MAV_2756|M.avium_104                AIAELIRVLKVGGTLAVSVPRWLPERVC---WLLSDEYHSNEGGHVR---
Mflv_1100|M.gilvum_PYR-GCK          AISELVRVLKPGGALAITVPRWLPERIC---WALSDEYHANEGGHIR---
Mvan_5717|M.vanbaalenii_PYR-1       AIAELVRVLKPGGALAITVPRWLPERIC---WALSDEYHANEGGHIR---
MSMEG_6483|M.smegmatis_MC2_155      AISELVRVLKPGGSLAITVPRWLPEKIC---WLLSDEYHANEGGHIR---
TH_0087|M.thermoresistible__bu      AIAELVRVLKPGGKLVVTVPRWLPERIC---WLLSDEYHANEGGHVR---
Mb1440c|M.bovis_AF2122/97           AADELVRVCRPGG--TIGVISWTCEGFFGRMLATIRPYRPSVSADLPPSA
Rv1405c|M.tuberculosis_H37Rv        AADELVRVCRPGG--TIGVISWTCEGFFGRMLATIRPYRPSVSADLPPSA
MUL_1801|M.ulcerans_Agy99           SANELARVCKTGG--TIGVISWTPEGFFGRMLATIRPYRPSLSAALPPSA
MLBr_00551|M.leprae_Br4923          AASELVRVCRPNG--TIGVISWTQEGFFGRMLATIRPYRPSLSAALPPAA
MAB_4481|M.abscessus_ATCC_1997      LGEEMLRVTRPGGLAILSYTVWLG------------PFGGHEMGLTH---
                                       *: ** : .*   :    *               :     .      

MMAR_2924|M.marinum_M               VYRASELREKITRHPMALTHAHHAHALHSPFWWLKCAVGVSNADH-PLVS
MAV_2756|M.avium_104                IYRASDLRAKILSGGMTLTHAHHAHALHSPFWWLKCAVGVHNTDH-RAVA
Mflv_1100|M.gilvum_PYR-GCK          IYRADELRDKVLAHGLTLTHTHHSHALHSPFWWLKCAVGTEKNDH-PAVA
Mvan_5717|M.vanbaalenii_PYR-1       IYRADELRDKVLAHGLALTHIHHAHALHSPYWWLKCAVGTEKTNH-PAVA
MSMEG_6483|M.smegmatis_MC2_155      IYKADELRDKVLAHGLELTHTHHEHALHSPYWWLKCLVGTEKNDH-PAVK
TH_0087|M.thermoresistible__bu      IYRADELRDKITRHGLRLTHRHHAHALHSPFWWLKCAVGTNNDRH-FAVR
Mb1440c|M.bovis_AF2122/97           LWGREAYVTGLLGDGVTGLKTARGLLEVKRFDTAQAVHDYFKNNYGPTIE
Rv1405c|M.tuberculosis_H37Rv        LWGREAYVTGLLGDGVTGLKTARGLLEVKRFDTAQAVHDYFKNNYGPTIE
MUL_1801|M.ulcerans_Agy99           LWGREAYARGLFGNHVSDIQTQRGQLEVTRFQTAQAVHDYFKNHYGPTIE
MLBr_00551|M.leprae_Br4923          LWGREAYIRGLLDDTVTNVKTERRQLEVKRFNSAEGVHNYFKNHYGPTIE
MAB_4481|M.abscessus_ATCC_1997      YFGGARAARWYTRKHGHPPKNNYGSSLFPVSVRDGLRWARDTGTLTAAFP
                                     :                 :                     .      . 

MMAR_2924|M.marinum_M               AYHKLLVWDLMRRPRVTRMAESVLNPLVGKSVAMYFDKRESAQSPADLGH
MAV_2756|M.avium_104                AYHKLLVWDLMRRPKITQLAESLLNPLVGKSVAMYFVKRQDAKSQATAGY
Mflv_1100|M.gilvum_PYR-GCK          AYHKLLVWDMMSQPWLTRTAEAALNPLIGKSVALYFRKPADTDA------
Mvan_5717|M.vanbaalenii_PYR-1       AYHKLLVWDMMGRPWLTRTAEAALNPLIGKSVALYFRKPAAADA------
MSMEG_6483|M.smegmatis_MC2_155      AYHQLLVWDMMGRPWLTRTAESALNPLIGKSVALYFTKPDARG-------
TH_0087|M.thermoresistible__bu      AYHQLLVWDMVRRPWVTRWAEEMLNPLIGKSVALYFDKPEVAGADS----
Mb1440c|M.bovis_AF2122/97           AYAHIGDNAVLAAELDRQLVELAAQYLSDGVMEWEYLLLTAEKR------
Rv1405c|M.tuberculosis_H37Rv        AYAHIGDNAVLAAELDRQLVELAAQYLSDGVMEWEYLLLTAEKR------
MUL_1801|M.ulcerans_Agy99           AYANIGDNAVLAAELDAQLVELADQYLTDGVMEWEYLVLTGTKK------
MLBr_00551|M.leprae_Br4923          AYTNIGDNSVLAAELDAQLTELAQKYLTNSTMGWEYLLLTAQKH------
MAB_4481|M.abscessus_ATCC_1997      RYHPKWAWWITKIPALREVLVSNLVLVLRPR-------------------
                                     *       :       .        :                       

MMAR_2924|M.marinum_M               SVASA
MAV_2756|M.avium_104                SIASV
Mflv_1100|M.gilvum_PYR-GCK          -----
Mvan_5717|M.vanbaalenii_PYR-1       -----
MSMEG_6483|M.smegmatis_MC2_155      -----
TH_0087|M.thermoresistible__bu      -----
Mb1440c|M.bovis_AF2122/97           -----
Rv1405c|M.tuberculosis_H37Rv        -----
MUL_1801|M.ulcerans_Agy99           -----
MLBr_00551|M.leprae_Br4923          -----
MAB_4481|M.abscessus_ATCC_1997      -----