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TIDTPIREDVSLAATHRAMWALGDYALMAEEVMAPLGPILVAAAGIGPGVRVLDVAAGSGNISLPAAKSG ATVVSTDLTPELLQRSKARAAAQGLTLDYQEANAQALPFGDSEFDTVISAIGVMFAPDHQCSANELARVC KTGGTIGVISWTPEGFFGRMLATIRPYRPSLSAALPPSALWGREAYARGLFGNHVSDIQTQRGQLEVTRF QTAQAVHDYFKNHYGPTIEAYANIGDNAVLAAELDAQLVELADQYLTDGVMEWEYLVLTGTKK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2214 | - | - | 100% (274) | methyltransferase |
| M. marinum M | MMAR_2212 | - | 2e-96 | 60.58% (274) | methyltransferase |
| M. marinum M | MMAR_1627 | - | 7e-73 | 50.75% (266) | methyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1440c | - | 1e-132 | 85.04% (274) | putative methyltransferase |
| M. gilvum PYR-GCK | Mflv_4060 | - | 2e-64 | 44.60% (278) | methyltransferase type 11 |
| M. tuberculosis H37Rv | Rv1405c | - | 1e-132 | 85.04% (274) | putative methyltransferase |
| M. leprae Br4923 | MLBr_00551 | - | 1e-121 | 77.29% (273) | putative methyltransferase |
| M. abscessus ATCC 19977 | MAB_0867c | - | 2e-09 | 36.84% (95) | putative transferase |
| M. avium 104 | MAV_3373 | - | 1e-115 | 74.09% (274) | methyltransferase, UbiE/COQ5 family protein |
| M. smegmatis MC2 155 | MSMEG_2285 | - | 1e-77 | 51.32% (265) | methyltransferase type 11 |
| M. thermoresistible (build 8) | TH_2937 | - | 3e-13 | 32.67% (150) | PUTATIVE Methyltransferase type 11 |
| M. ulcerans Agy99 | MUL_1801 | - | 1e-154 | 99.27% (274) | methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_1928 | - | 6e-67 | 45.56% (270) | methyltransferase type 11 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4060|M.gilvum_PYR-GCK MATVDN------EDDRALKAKHRALWASGDYPAVAAELIPSLGPELVRAC
Mvan_1928|M.vanbaalenii_PYR-1 MTTANAGVASDPDADRQLKAKHRALWASGDYPAVAVDLIHSLGPRLVEAC
MSMEG_2285|M.smegmatis_MC2_155 MGVVTV--------DRELEAKHRALWALGNYGAIAAHIVAPLGPVLVEAC
MMAR_2214|M.marinum_M MTIDTPIR-----EDVSLAATHRAMWALGDYALMAEEVMAPLGPILVAAA
MUL_1801|M.ulcerans_Agy99 MTIDTPIR-----EDVSLAATHRAMWALGDYALMAEEVMAPLGPILVAAA
Mb1440c|M.bovis_AF2122/97 MTIDTPAR-----EDQTLAATHRAMWALGDYALMAEEVMAPLGPILVAAA
Rv1405c|M.tuberculosis_H37Rv MTIDTPAR-----EDQTLAATHRAMWALGDYALMAEEVMAPLGPILVAAA
MLBr_00551|M.leprae_Br4923 MNLYTPIH-----EDQSLAAIHRAMWALGDYALMAEEVMAPLGPILVTAT
MAV_3373|M.avium_104 MTLDTTT------ADASVAARHRTVWALGDYALMAEEVMAPLGPTLVEAA
TH_2937|M.thermoresistible__bu ---------------------VTTNWAAGRYEAVGERIAPIADEVLDAAA
MAB_0867c|M.abscessus_ATCC_199 MGAPTQN--------IFEDLYRDSLHEGGPIVPWDSKDAKPRIKELALLG
: * *
Mflv_4060|M.gilvum_PYR-GCK GVRS--GDRVLDVAAGSGNASIPAAAAGAVVTASDLTPELFDAGRRIAAE
Mvan_1928|M.vanbaalenii_PYR-1 RVGP--GQRVLDVAAGSGNAAIPAAEAGATVIAGDLTPELFEAGRETARR
MSMEG_2285|M.smegmatis_MC2_155 GIGP--GDRVLDIAAGTGNASIPAALAGAQVTASDLCPQLVDEGAHESAE
MMAR_2214|M.marinum_M GIGP--GVRVLDVAAGSGNISLPAAKSGATVVSTDLTPELLQRSKARAAA
MUL_1801|M.ulcerans_Agy99 GIGP--GVRVLDVAAGSGNISLPAAKSGATVVSTDLTSELLQRSKARAAA
Mb1440c|M.bovis_AF2122/97 GIGP--GVRVLDVAAGSGNISLPAAKTGATVISTDLTPELLQRSQARAAQ
Rv1405c|M.tuberculosis_H37Rv GIGP--GVRVLDVAAGSGNISLPAAKTGATVISTDLTPELLQRSQARAAQ
MLBr_00551|M.leprae_Br4923 GIRP--GMQVLDVAAGSGNISLPAAKTGATIVSTDLTPELLQRSQARATE
MAV_3373|M.avium_104 GIGP--GVRVLDVAAGSGNITLPAAAAGASVVSTDLTPELLQRSRDRAAG
TH_2937|M.thermoresistible__bu RRTPLRGATLVDLACGTGSAALSATARGAAVTGVDITSELIALAAGKPG-
MAB_0867c|M.abscessus_ATCC_199 AIRG----DVLDIGCGLGDNAIYLAQQGFNVTGLDFAPSAIEQAKGRAAA
::*:..* *. :: : * : . *: .. . . .
Mflv_4060|M.gilvum_PYR-GCK RGVAVEWVEADAEALPFPDDSFDVVMS--CVGAMFAPHHQATADEIVRVT
Mvan_1928|M.vanbaalenii_PYR-1 RGVEVQWMEADAEAMPFADNDFDVVMS--CVGAMFAPHHQATADELVRVT
MSMEG_2285|M.smegmatis_MC2_155 RGVDITWKEANAEALPFSDGEFDVVMS--CIGVMFAPHHDQSARELLRVT
MMAR_2214|M.marinum_M QGLTLDYQEANAQALPFGDSEFDTVIS--AIGVMFAPDHQCSANELARVC
MUL_1801|M.ulcerans_Agy99 QELTLDYQEANAQALPFGDSEFDTVIS--AIGVMFAPDHQCSANELARVC
Mb1440c|M.bovis_AF2122/97 QGLTLQYQEANAQALPFADDEFDTVIS--AIGVMFAPDHQAAADELVRVC
Rv1405c|M.tuberculosis_H37Rv QGLTLQYQEANAQALPFADDEFDTVIS--AIGVMFAPDHQAAADELVRVC
MLBr_00551|M.leprae_Br4923 LGLTLEYREADAQALPFGDGEFDVVMS--AIGVMFAPDHRRAASELVRVC
MAV_3373|M.avium_104 MGLTIDYREANAQALPFGDGEFDAVVS--AIGVQFAPDHQRAADELVRVC
TH_2937|M.thermoresistible__bu -GSTVTWVTADAADTGLKTASFDVAVS--NMGIIFVPPDRQVA-ELARLL
MAB_0867c|M.abscessus_ATCC_199 AGVAVDFQVADATTLDGWDARFDTVIDSGVYHCFDAEGHTEYASALHRAT
: : *:* **..:. . . * : *
Mflv_4060|M.gilvum_PYR-GCK RPGGTLGLISWTPEGFIGHLFATMKPYAPPPPPGASPPPMWGSENHVEAL
Mvan_1928|M.vanbaalenii_PYR-1 RPGGTIGLINWTPEGFIGNLFATMKPYAPPPPPGASPAPLWGNAEHVREL
MSMEG_2285|M.smegmatis_MC2_155 RSGGRIGLISWTPEGFIGQLFATMKPFVPAPPPGVSPPPLWGNADHVRTL
MMAR_2214|M.marinum_M KTGGTIGVISWTPEGFFGRMLATIRPYRPSLSAALPPSALWGREAYARGL
MUL_1801|M.ulcerans_Agy99 KTGGTIGVISWTPEGFFGRMLATIRPYRPSLSAALPPSALWGREAYARGL
Mb1440c|M.bovis_AF2122/97 RPGGTIGVISWTCEGFFGRMLATIRPYRPSVSADLPPSALWGREAYVTGL
Rv1405c|M.tuberculosis_H37Rv RPGGTIGVISWTCEGFFGRMLATIRPYRPSVSADLPPSALWGREAYVTGL
MLBr_00551|M.leprae_Br4923 RPNGTIGVISWTQEGFFGRMLATIRPYRPSLSAALPPAALWGREAYIRGL
MAV_3373|M.avium_104 RPGGRIGLISWTPEGFFGRMLATIRPYRPSLSHPVPPAALWGRPGYVRAL
TH_2937|M.thermoresistible__bu KPGGVLSFSAWIRTDEN-PFSDPVAEVLGPPPAGFSPD-QWGDAETLTER
MAB_0867c|M.abscessus_ATCC_199 RPGARWYIWCFAQGAVHGVPTPFQNGQRAEEIEQVLTTSGWS--------
:... . : . *.
Mflv_4060|M.gilvum_PYR-GCK FGDRVRDLTMRRQTVRFDHCASPLDFREYWKRNYGPTLAAYRFNE--DRP
Mvan_1928|M.vanbaalenii_PYR-1 FADRVTDLQMQRQTVVMDHCATPLEFREYWKANYGPTIATYRFNA--DDA
MSMEG_2285|M.smegmatis_MC2_155 LGDGIEDFETQRRSLTVDMFADGAAFRDFFKANYGPTIAAYRAVG--DDA
MMAR_2214|M.marinum_M FGNHVSDIQTQRGQLEVTRFQTAQAVHDYFKNHYGPTIEAYANIG--DNA
MUL_1801|M.ulcerans_Agy99 FGNHVSDIQTQRGQLEVTRFQTAQAVHDYFKNHYGPTIEAYANIG--DNA
Mb1440c|M.bovis_AF2122/97 LGDGVTGLKTARGLLEVKRFDTAQAVHDYFKNNYGPTIEAYAHIG--DNA
Rv1405c|M.tuberculosis_H37Rv LGDGVTGLKTARGLLEVKRFDTAQAVHDYFKNNYGPTIEAYAHIG--DNA
MLBr_00551|M.leprae_Br4923 LDDTVTNVKTERRQLEVKRFNSAEGVHNYFKNHYGPTIEAYTNIG--DNS
MAV_3373|M.avium_104 LGERIGEITTARGMLPVNRFGSAEDVHAYFKQHYGPTIEAYANIG--HNR
TH_2937|M.thermoresistible__bu LTPHFDAIDLIRG-LHPWEFDSPATALHFLRTESPVHVEIFRRAGPARRE
MAB_0867c|M.abscessus_ATCC_199 -------------VLQINPTTMSAPKAEFLNAIRG----SYRGDP-----
: : . :
Mflv_4060|M.gilvum_PYR-GCK ERLAELDAAFLDFLTTWNQADGTDGTAYDAEYLLVTATKR--
Mvan_1928|M.vanbaalenii_PYR-1 ERVAALDRDFLAFLEQWNQSGETGRTAYEAEYLLVTATKR--
MSMEG_2285|M.smegmatis_MC2_155 ERTAALDEAIALLGDRYLDSG-----AMQWEYLVVTAHKR--
MMAR_2214|M.marinum_M VLAAELDAQLVELADQYLTDG-----VMEWEYLVLTGTKK--
MUL_1801|M.ulcerans_Agy99 VLAAELDAQLVELADQYLTDG-----VMEWEYLVLTGTKK--
Mb1440c|M.bovis_AF2122/97 VLAAELDRQLVELAAQYLSDG-----VMEWEYLLLTAEKR--
Rv1405c|M.tuberculosis_H37Rv VLAAELDRQLVELAAQYLSDG-----VMEWEYLLLTAEKR--
MLBr_00551|M.leprae_Br4923 VLAAELDAQLTELAQKYLTNS-----TMGWEYLLLTAQKH--
MAV_3373|M.avium_104 VLAAELDAQLVELAAQHLSDG-----TMGWEYLLVTAEKRSG
TH_2937|M.thermoresistible__bu RLAAAFRSALRPHAGPAGTVG------FTAPYVIVTARRRG-
MAB_0867c|M.abscessus_ATCC_199 ---AVLDRLDQDVTDPLLHVP---------VYTVIAERM---
* : * :::