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VPDITDLFAQRATLRRSTSLLTAFRFEQSAPERFYGTLAQDTVHLITDLWQQAEGVALRGRTVLDVGGGP GYFASAFADAGARYIGVEPDPREMHAAPQGHRGIQDPRTTYLRASGMALPLADNSVDICLSSNVAEHVPQ PWRLGEEMLRVTRPGGLAILSYTVWLGPFGGHEMGLTHYFGGARAARWYTRKHGHPPKNNYGSSLFPVSV RDGLRWARDTGTLTAAFPRYHPKWAWWITKIPALREVLVSNLVLVLRPR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4481 | - | - | 100% (259) | hypothetical protein MAB_4481 |
| M. abscessus ATCC 19977 | MAB_3364 | - | 1e-09 | 36.89% (103) | hypothetical protein MAB_3364 |
| M. abscessus ATCC 19977 | MAB_3689 | - | 2e-06 | 31.67% (120) | putative methyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0229c | - | 1e-104 | 70.20% (255) | methyltransferase (methylase) |
| M. gilvum PYR-GCK | Mflv_0427 | - | 1e-107 | 72.55% (255) | methyltransferase type 11 |
| M. tuberculosis H37Rv | Rv0224c | - | 1e-103 | 69.80% (255) | methyltransferase (methylase) |
| M. leprae Br4923 | MLBr_02584 | - | 1e-106 | 69.38% (258) | hypothetical protein MLBr_02584 |
| M. marinum M | MMAR_0473 | - | 1e-109 | 72.66% (256) | methyltransferase |
| M. avium 104 | MAV_4945 | - | 1e-108 | 71.09% (256) | SAM-dependent methyltransferase |
| M. smegmatis MC2 155 | MSMEG_2350 | - | 6e-10 | 36.27% (102) | hypothetical protein MSMEG_2350 |
| M. thermoresistible (build 8) | TH_2028 | - | 1e-109 | 73.15% (257) | POSSIBLE METHYLTRANSFERASE (METHYLASE) |
| M. ulcerans Agy99 | MUL_1123 | - | 1e-108 | 72.66% (256) | methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_0241 | - | 1e-109 | 73.62% (254) | methyltransferase type 11 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0427|M.gilvum_PYR-GCK MAA--------------TDLLAGRATLSRSLRLLSAFRFEQTDPDRFYGA
Mvan_0241|M.vanbaalenii_PYR-1 MPA--------------TDRFSDRATLARSVRLLTAFRFEQSAPDRFYGA
TH_2028|M.thermoresistible__bu MDAPR-----AAARRDVTELFARRATLRRSVRLLSEFRFEQSDPARFYGA
Mb0229c|M.bovis_AF2122/97 --------------MAVTDVFARRATLRRSLRLLADFRYEQRDPARFYRT
Rv0224c|M.tuberculosis_H37Rv --------------MAVTDVFARRATLRRSLRLLADFRYEQRDPARFYRT
MLBr_02584|M.leprae_Br4923 MDTRRRVWPVAIITPHVTDVFAQRATLTRSLQLLSEFRYEQPYPARFYRA
MMAR_0473|M.marinum_M --------------MAVTDRFARRATLSRSLRLLSEFRYEQPDPARFYGA
MUL_1123|M.ulcerans_Agy99 --------------MAVTDRFARRATLSRSLRLLSEFRYEQPDPARFYGA
MAV_4945|M.avium_104 ----------------MTDIFARRATLARSVRLLSQFRYERSEPARFYGA
MAB_4481|M.abscessus_ATCC_1997 -------------MPDITDLFAQRATLRRSTSLLTAFRFEQSAPERFYGT
MSMEG_2350|M.smegmatis_MC2_155 -----------------------MGDPDNALPSALPLTGERTIP----GL
. .: : *: *
Mflv_0427|M.gilvum_PYR-GCK LASDTVAMVDDLWRATTGTSTRNLTVLDVGGGPGYFASAFTDAGLHYVGV
Mvan_0241|M.vanbaalenii_PYR-1 LADDTVAMVGDLWESATGESQAGLTLLDVGGGPGYFASAFTAAGVNYIGV
TH_2028|M.thermoresistible__bu LADDTAALVADLWRAATGSDPAGRTVLDVGGGPGYFAAAFARAGMRYIGV
Mb0229c|M.bovis_AF2122/97 LAADTAAMIGDLWLATHSEPPVGRTLLDVGGGPGYFATAFSDAGVGYIGV
Rv0224c|M.tuberculosis_H37Rv LAADTAAMIGDLWLATHSEPPVGRTLLDVGGGPGYFATAFSDAGVGYIGV
MLBr_02584|M.leprae_Br4923 LAADTVAMVGDLWLSTHGAPPVGRILLDVGSGSGYFAAAFADAGVRYIGV
MMAR_0473|M.marinum_M LAADTATLVSDLWLAARGESVAGRTLLDVGGGPGYFASAFAAAGVGYIGV
MUL_1123|M.ulcerans_Agy99 LAADTATLVSDLWLAARGESVAGRTLLDVGGGPGYFASAFAAAGVGYIGV
MAV_4945|M.avium_104 LAADTAAMVDDLWRAGHGESAAGRTLLDVGGGPGYFAAAFADAGVRYLGV
MAB_4481|M.abscessus_ATCC_1997 LAQDTVHLITDLWQQAEGVALRGRTVLDVGGGPGYFASAFADAGARYIGV
MSMEG_2350|M.smegmatis_MC2_155 AEENYWFRRHEVVYQRLAHRCAGRDVLEAGCGEGYGADLIADVARRVIGL
: :: . . :*:.* * ** * :: .. :*:
Mflv_0427|M.gilvum_PYR-GCK EPDPGEMHAAAPRTHSR----AGSFVRASGTALPFADGSVDICLSSNVAE
Mvan_0241|M.vanbaalenii_PYR-1 EPDPREMHAAAALTHER----AGTFVRASGTALPFADDSVDVCLSSNVAE
TH_2028|M.thermoresistible__bu EPDPREIHAGPAVECPEDDPAAGTFVRASGMALPFADASVDICLSSNVAE
Mb0229c|M.bovis_AF2122/97 EPDPDEMHAAGPAFTGR----PGMFVRASGMALPLADDSVDICLSSNVAE
Rv0224c|M.tuberculosis_H37Rv EPDPDEMHAAGPAFTGR----PGMFVRASGMALPFADDSVDICLSSNVAE
MLBr_02584|M.leprae_Br4923 EPDPREMHAAGPALVPK----AGAFVRASGMALPFADDAVDICLSSNVAE
MMAR_0473|M.marinum_M EPDPNEMHAAGPAHAGG----PGSFVRASGMALPFADDSVDICLSSNVAE
MUL_1123|M.ulcerans_Agy99 EPDPNEMHAAGPAHAGG----PGSFVRASGMALPLADDSVDICLSSNVAE
MAV_4945|M.avium_104 EPDPGEMHAAGPVVAAD----TGTFVRASGMALPFADDSVDICLSSNVAE
MAB_4481|M.abscessus_ATCC_1997 EPDPREMHAAPQGHRGIQDP-RTTYLRASGMALPLADNSVDICLSSNVAE
MSMEG_2350|M.smegmatis_MC2_155 DYDEATVAHVRARYPRV------DIRHGNLAELPLPDASVDVVVNFQVIE
: * : :.. **:.* :**: :. :* *
Mflv_0427|M.gilvum_PYR-GCK HVAQPWRLGEEMLRVTRPGGLAVLSYTVWLGPFGGHEMGLSHYLG---GY
Mvan_0241|M.vanbaalenii_PYR-1 HVAQPWRLGDEMLRVTRPGGLAVLSYTVWLGPFGGHEMGLTHYLG---GR
TH_2028|M.thermoresistible__bu HVPQPWLLGREMLRVTRPGGLAVLSYTVWLGPFGGHETGLWHYLG---GR
Mb0229c|M.bovis_AF2122/97 HVPRPWQLGTEMLRVTKPGGLVVLSYTVWLGPFGGHEMGLSHYLG---GA
Rv0224c|M.tuberculosis_H37Rv HVPRPWQLGTEMLRVTKPGGLVVLSYTVWLGPFGGHEMGLSHYLG---GA
MLBr_02584|M.leprae_Br4923 HVPQPWQLGNEMLRVTKPGGLVVLSYTIWLGPFGGHEMGLTHYLG---GA
MMAR_0473|M.marinum_M HVPRPWQLGAEMLRVTRPGGLAVLSYTVWLGPFGGHEMGLSHYLG---GA
MUL_1123|M.ulcerans_Agy99 HVPRPWQLGAEMLRVTRPGGLAVLSYTVWLGPFGGHEMGLSHYLG---GA
MAV_4945|M.avium_104 HVPRPWQLGAEMLRVTRPGGLAVLSYTVWLGPFGGHEMGLTHYLG---GS
MAB_4481|M.abscessus_ATCC_1997 HVPQPWRLGEEMLRVTRPGGLAILSYTVWLGPFGGHEMGLTHYFG---GA
MSMEG_2350|M.smegmatis_MC2_155 HLWDQAQFVSECFRVLRPGGVFLVSTPNRITFSPGRDTPLNPFHTRELNA
*: : * :** :***: ::* . : *:: * : .
Mflv_0427|M.gilvum_PYR-GCK RAAERYTRRHGHRPKNDYGSSLFAVSAADGLRWARSTGALAAAFPRYHPR
Mvan_0241|M.vanbaalenii_PYR-1 RAAEMYTRRHGHRPKNDYGSSLFAVHARDGLRWAQGTGALLAAFPRYHPR
TH_2028|M.thermoresistible__bu RAADRYARRHGHRPKNDYGSSLFAVSAADGLRWAAATGALLAAFPRYHPK
Mb0229c|M.bovis_AF2122/97 RAAARYVRKHGHPAKNNYGSSLFAVSAAEGLRWAAGTGAALAVFPRYHPR
Rv0224c|M.tuberculosis_H37Rv RAAARYVRKHGHPAKNNYGSSLFAVSAAEGLRWAAGTGAALAVFPRYHPR
MLBr_02584|M.leprae_Br4923 RAATRYVRKHGHRAKNDYGSSLFPVSAADGLNWAASTGVAVAAFPRYHPR
MMAR_0473|M.marinum_M RAAARYARRHGHPAKNNYGSSLFAVSAAEGLRWAEGTGTLIAAFPRYHPR
MUL_1123|M.ulcerans_Agy99 RAAARYARRHGHPAKNNYGSSLFAVSAAEGLRWAEGTGTLIAAFPRYHPR
MAV_4945|M.avium_104 RAAARYARKHGHPAKNNYGSSLFEVSVADGLAWAACTGAELAAFPRYHPR
MAB_4481|M.abscessus_ATCC_1997 RAARWYTRKHGHPPKNNYGSSLFPVSVRDGLRWARDTGTLTAAFPRYHPK
MSMEG_2350|M.smegmatis_MC2_155 AELTELLETAGFEVEDTLG--VFHGAGLAELDARHGGSIIEAQVQRAVAD
. *. :: * :* * . * . * .
Mflv_0427|M.gilvum_PYR-GCK WAWGLTRVPGVREFLVSNLVLVLRPT----------------
Mvan_0241|M.vanbaalenii_PYR-1 WAWGLTKVPGLREFLVSNLVLVLRPC----------------
TH_2028|M.thermoresistible__bu WGWWLTRAPVVREFLVSNLVLVLSPPEIVN------------
Mb0229c|M.bovis_AF2122/97 WAWWLTSVPVLREFLVSNLVLVLTP-----------------
Rv0224c|M.tuberculosis_H37Rv WAWWLTSVPVLREFLVSNLVLVLTP-----------------
MLBr_02584|M.leprae_Br4923 WAWWLTSVPVLREFVVSNLVLVLRPR----------------
MMAR_0473|M.marinum_M WAWWMTSVPMLREFLVSNLVLVLSPR----------------
MUL_1123|M.ulcerans_Agy99 SAWWMTSVPMLREFLVSNLVLVLSPR----------------
MAV_4945|M.avium_104 WAWWLTSVPVLREFLVSNLVLVLQPQ----------------
MAB_4481|M.abscessus_ATCC_1997 WAWWITKIPALREVLVSNLVLVLRPR----------------
MSMEG_2350|M.smegmatis_MC2_155 APWDEQLLADVAAVRTDDFDLTPAAERDIDDSLDLVAIAVRP
* . : . ..:: *. .