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TIDTPIREDVSLAATHRAMWALGDYALMAEEVMAPLGPILVAAAGIGPGVRVLDVAAGSGNISLPAAKSG ATVVSTDLTSELLQRSKARAAAQELTLDYQEANAQALPFGDSEFDTVISAIGVMFAPDHQCSANELARVC KTGGTIGVISWTPEGFFGRMLATIRPYRPSLSAALPPSALWGREAYARGLFGNHVSDIQTQRGQLEVTRF QTAQAVHDYFKNHYGPTIEAYANIGDNAVLAAELDAQLVELADQYLTDGVMEWEYLVLTGTKK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_1801 | - | - | 100% (274) | methyltransferase |
| M. ulcerans Agy99 | MUL_1798 | - | 1e-92 | 58.76% (274) | methyltransferase |
| M. ulcerans Agy99 | MUL_3409 | - | 2e-70 | 49.62% (266) | methyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1440c | - | 1e-130 | 84.31% (274) | putative methyltransferase |
| M. gilvum PYR-GCK | Mflv_4060 | - | 2e-62 | 43.88% (278) | methyltransferase type 11 |
| M. tuberculosis H37Rv | Rv1405c | - | 1e-130 | 84.31% (274) | putative methyltransferase |
| M. leprae Br4923 | MLBr_00551 | - | 1e-119 | 76.56% (273) | putative methyltransferase |
| M. abscessus ATCC 19977 | MAB_3930c | - | 3e-09 | 31.82% (110) | ubiquinone/menaquinone biosynthesis methlytransferase UbiE |
| M. marinum M | MMAR_2214 | - | 1e-154 | 99.27% (274) | methyltransferase |
| M. avium 104 | MAV_3373 | - | 1e-113 | 73.36% (274) | methyltransferase, UbiE/COQ5 family protein |
| M. smegmatis MC2 155 | MSMEG_2285 | - | 7e-76 | 50.57% (265) | methyltransferase type 11 |
| M. thermoresistible (build 8) | TH_2937 | - | 2e-13 | 32.00% (150) | PUTATIVE Methyltransferase type 11 |
| M. vanbaalenii PYR-1 | Mvan_1928 | - | 4e-65 | 44.81% (270) | methyltransferase type 11 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4060|M.gilvum_PYR-GCK MATVDN------EDDRALKAKHRALWASGDYPAVAAELIPS--LGPELVR
Mvan_1928|M.vanbaalenii_PYR-1 MTTANAGVASDPDADRQLKAKHRALWASGDYPAVAVDLIHS--LGPRLVE
MSMEG_2285|M.smegmatis_MC2_155 MGVVTV--------DRELEAKHRALWALGNYGAIAAHIVAP--LGPVLVE
MUL_1801|M.ulcerans_Agy99 MTIDTPIR-----EDVSLAATHRAMWALGDYALMAEEVMAP--LGPILVA
MMAR_2214|M.marinum_M MTIDTPIR-----EDVSLAATHRAMWALGDYALMAEEVMAP--LGPILVA
Mb1440c|M.bovis_AF2122/97 MTIDTPAR-----EDQTLAATHRAMWALGDYALMAEEVMAP--LGPILVA
Rv1405c|M.tuberculosis_H37Rv MTIDTPAR-----EDQTLAATHRAMWALGDYALMAEEVMAP--LGPILVA
MLBr_00551|M.leprae_Br4923 MNLYTPIH-----EDQSLAAIHRAMWALGDYALMAEEVMAP--LGPILVT
MAV_3373|M.avium_104 MTLDTTT------ADASVAARHRTVWALGDYALMAEEVMAP--LGPTLVE
TH_2937|M.thermoresistible__bu ---------------------VTTNWAAGRYEAVGERIAPI--ADEVLDA
MAB_3930c|M.abscessus_ATCC_199 MNRATLEK-----DPHEVASMFDAVARRYDITNTVLSFGRDRFWRRATRE
: .
Mflv_4060|M.gilvum_PYR-GCK ACGVRS--GDRVLDVAAGSGNASIPAAAAGAVVTASDLTPELFDAGRRIA
Mvan_1928|M.vanbaalenii_PYR-1 ACRVGP--GQRVLDVAAGSGNAAIPAAEAGATVIAGDLTPELFEAGRETA
MSMEG_2285|M.smegmatis_MC2_155 ACGIGP--GDRVLDIAAGTGNASIPAALAGAQVTASDLCPQLVDEGAHES
MUL_1801|M.ulcerans_Agy99 AAGIGP--GVRVLDVAAGSGNISLPAAKSGATVVSTDLTSELLQRSKARA
MMAR_2214|M.marinum_M AAGIGP--GVRVLDVAAGSGNISLPAAKSGATVVSTDLTPELLQRSKARA
Mb1440c|M.bovis_AF2122/97 AAGIGP--GVRVLDVAAGSGNISLPAAKTGATVISTDLTPELLQRSQARA
Rv1405c|M.tuberculosis_H37Rv AAGIGP--GVRVLDVAAGSGNISLPAAKTGATVISTDLTPELLQRSQARA
MLBr_00551|M.leprae_Br4923 ATGIRP--GMQVLDVAAGSGNISLPAAKTGATIVSTDLTPELLQRSQARA
MAV_3373|M.avium_104 AAGIGP--GVRVLDVAAGSGNITLPAAAAGASVVSTDLTPELLQRSRDRA
TH_2937|M.thermoresistible__bu AARRTPLRGATLVDLACGTGSAALSATARGAAVTGVDITSELIALAAGKP
MAB_3930c|M.abscessus_ATCC_199 ALRLKP--GDKVLDIAAGTAVSTAELTQSGAWCVAADFSVGMLKAG----
* . * ::*:*.*:. : : ** . *: :. .
Mflv_4060|M.gilvum_PYR-GCK AERGVAVEWVEADAEALPFPDDSFDVVMSCVGAMFAPHHQATADEIVRVT
Mvan_1928|M.vanbaalenii_PYR-1 RRRGVEVQWMEADAEAMPFADNDFDVVMSCVGAMFAPHHQATADELVRVT
MSMEG_2285|M.smegmatis_MC2_155 AERGVDITWKEANAEALPFSDGEFDVVMSCIGVMFAPHHDQSARELLRVT
MUL_1801|M.ulcerans_Agy99 AAQELTLDYQEANAQALPFGDSEFDTVISAIGVMFAPDHQCSANELARVC
MMAR_2214|M.marinum_M AAQGLTLDYQEANAQALPFGDSEFDTVISAIGVMFAPDHQCSANELARVC
Mb1440c|M.bovis_AF2122/97 AQQGLTLQYQEANAQALPFADDEFDTVISAIGVMFAPDHQAAADELVRVC
Rv1405c|M.tuberculosis_H37Rv AQQGLTLQYQEANAQALPFADDEFDTVISAIGVMFAPDHQAAADELVRVC
MLBr_00551|M.leprae_Br4923 TELGLTLEYREADAQALPFGDGEFDVVMSAIGVMFAPDHRRAASELVRVC
MAV_3373|M.avium_104 AGMGLTIDYREANAQALPFGDGEFDAVVSAIGVQFAPDHQRAADELVRVC
TH_2937|M.thermoresistible__bu G--GSTVTWVTADAADTGLKTASFDVAVSNMGIIFVPPDRQVA-ELARLL
MAB_3930c|M.abscessus_ATCC_199 --ARRDVPKVAGDATRLPFADHSFDAVTISFGLRNVVDHVEGLREMARVT
: .:* : .**.. .* . . *: *:
Mflv_4060|M.gilvum_PYR-GCK RPGGTLGLISWTPEGFIGHLFATMKPYAPPPPPGASPPPMWGSENHVEAL
Mvan_1928|M.vanbaalenii_PYR-1 RPGGTIGLINWTPEGFIGNLFATMKPYAPPPPPGASPAPLWGNAEHVREL
MSMEG_2285|M.smegmatis_MC2_155 RSGGRIGLISWTPEGFIGQLFATMKPFVPAPPPGVSPPPLWGNADHVRTL
MUL_1801|M.ulcerans_Agy99 KTGGTIGVISWTPEGFFGRMLATIRPYRPSLSAALPPSALWGREAYARGL
MMAR_2214|M.marinum_M KTGGTIGVISWTPEGFFGRMLATIRPYRPSLSAALPPSALWGREAYARGL
Mb1440c|M.bovis_AF2122/97 RPGGTIGVISWTCEGFFGRMLATIRPYRPSVSADLPPSALWGREAYVTGL
Rv1405c|M.tuberculosis_H37Rv RPGGTIGVISWTCEGFFGRMLATIRPYRPSVSADLPPSALWGREAYVTGL
MLBr_00551|M.leprae_Br4923 RPNGTIGVISWTQEGFFGRMLATIRPYRPSLSAALPPAALWGREAYIRGL
MAV_3373|M.avium_104 RPGGRIGLISWTPEGFFGRMLATIRPYRPSLSHPVPPAALWGRPGYVRAL
TH_2937|M.thermoresistible__bu KPGGVLSFSAWIRTDEN-PFSDPVAEVLGPPPAGFSPD-QWGDAETLTER
MAB_3930c|M.abscessus_ATCC_199 KPGGRLAVCEFS-TPVNRPFRTLYMEYLMKTLPEVARAVSSNPDAYVY--
:..* :.. : : . .
Mflv_4060|M.gilvum_PYR-GCK FGDRVRDLTMRRQTVRFDHCASPLDFREYWKRNYGPTLAAYRFNE--DRP
Mvan_1928|M.vanbaalenii_PYR-1 FADRVTDLQMQRQTVVMDHCATPLEFREYWKANYGPTIATYRFNA--DDA
MSMEG_2285|M.smegmatis_MC2_155 LGDGIEDFETQRRSLTVDMFADGAAFRDFFKANYGPTIAAYRAVG--DDA
MUL_1801|M.ulcerans_Agy99 FGNHVSDIQTQRGQLEVTRFQTAQAVHDYFKNHYGPTIEAYANIG--DNA
MMAR_2214|M.marinum_M FGNHVSDIQTQRGQLEVTRFQTAQAVHDYFKNHYGPTIEAYANIG--DNA
Mb1440c|M.bovis_AF2122/97 LGDGVTGLKTARGLLEVKRFDTAQAVHDYFKNNYGPTIEAYAHIG--DNA
Rv1405c|M.tuberculosis_H37Rv LGDGVTGLKTARGLLEVKRFDTAQAVHDYFKNNYGPTIEAYAHIG--DNA
MLBr_00551|M.leprae_Br4923 LDDTVTNVKTERRQLEVKRFNSAEGVHNYFKNHYGPTIEAYTNIG--DNS
MAV_3373|M.avium_104 LGERIGEITTARGMLPVNRFGSAEDVHAYFKQHYGPTIEAYANIG--HNR
TH_2937|M.thermoresistible__bu LTPHFDAIDLIRG-LHPWEFDSPATALHFLRTESPVHVEIFRRAGPARRE
MAB_3930c|M.abscessus_ATCC_199 LAESIRAWPDQEALAHQIASAGWSNVR--WRNLTGGIVALHIATL-----
: . . : : .
Mflv_4060|M.gilvum_PYR-GCK ERLAELDAAFLDFLTTWNQADGTDGTAYDAEYLLVTATKR--
Mvan_1928|M.vanbaalenii_PYR-1 ERVAALDRDFLAFLEQWNQSGETGRTAYEAEYLLVTATKR--
MSMEG_2285|M.smegmatis_MC2_155 ERTAALDEAIALLGDRYLDSG-----AMQWEYLVVTAHKR--
MUL_1801|M.ulcerans_Agy99 VLAAELDAQLVELADQYLTDG-----VMEWEYLVLTGTKK--
MMAR_2214|M.marinum_M VLAAELDAQLVELADQYLTDG-----VMEWEYLVLTGTKK--
Mb1440c|M.bovis_AF2122/97 VLAAELDRQLVELAAQYLSDG-----VMEWEYLLLTAEKR--
Rv1405c|M.tuberculosis_H37Rv VLAAELDRQLVELAAQYLSDG-----VMEWEYLLLTAEKR--
MLBr_00551|M.leprae_Br4923 VLAAELDAQLTELAQKYLTNS-----TMGWEYLLLTAQKH--
MAV_3373|M.avium_104 VLAAELDAQLVELAAQHLSDG-----TMGWEYLLVTAEKRSG
TH_2937|M.thermoresistible__bu RLAAAFRSALRPHAGPAGTVG------FTAPYVIVTARRRG-
MAB_3930c|M.abscessus_ATCC_199 ------------------------------------------