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SVDRDRILREAAECLGKRPTATQDEIAAAVGVSRATLHRHFAKRGALLEALDRLAISQLGEAMTISRCQE GTAAEALQRLVAACRPVSGYLRLLYIRAQDFESDQLTEGWAEIDAQLRQLFLRGQRSGEFRRDLPTLWLN QAFFSLVAGAGRSANTGRIARSDFTGMVTELLLRGARSS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2831 | - | - | 100% (180) | transcriptional regulator |
| M. marinum M | MMAR_1026 | - | 1e-59 | 61.67% (180) | TetR family transcriptional regulator |
| M. marinum M | MMAR_2830 | - | 1e-47 | 52.54% (177) | hypothetical protein MMAR_2830 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3185c | - | 3e-05 | 27.84% (176) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0240 | - | 5e-50 | 52.54% (177) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3160c | - | 3e-05 | 27.84% (176) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0984c | - | 8e-05 | 27.68% (112) | TetR family transcriptional regulator |
| M. avium 104 | MAV_1333 | - | 8e-05 | 27.27% (165) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6223 | - | 3e-08 | 25.60% (168) | TetR family protein transcriptional repressor LfrR |
| M. thermoresistible (build 8) | TH_4573 | - | 4e-05 | 35.06% (77) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_0778 | - | 3e-59 | 61.11% (180) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0665 | - | 3e-48 | 51.96% (179) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0240|M.gilvum_PYR-GCK ---------------MALSRDDLLRAAADFLGRR--PNATQDEIAAAVGV
Mvan_0665|M.vanbaalenii_PYR-1 ---------------MTATRDQLLRAAADFLGRR--PNATQDEIAAAIGV
MUL_0778|M.ulcerans_Agy99 ---------MMYYRLMALDHERLLRAAAEFLGRR--PNATQDEIAAAIGV
MMAR_2831|M.marinum_M ---------------MSVDRDRILREAAECLGKR--PTATQDEIAAAVGV
MAV_1333|M.avium_104 --------MSTDVSPATDTRELIVAAAFTCFGRQGLQKATIVDIAKQAGV
TH_4573|M.thermoresistible__bu -MATQRATADVEEQHESDRRDQILEAANACFAQLGIHRTSVQDVARAANV
Mb3185c|M.bovis_AF2122/97 --------MPRQAGRWSPTALRILGAAAELIALRGYSSTSTRDIAAAVGV
Rv3160c|M.tuberculosis_H37Rv --------MPRQAGRWSPTALRILGAAAELIALRGYSSTSTRDIAAAVGV
MSMEG_6223|M.smegmatis_MC2_155 -----MTSPSIESGARERTRRAILDAAMLVLADH--PTAALGDIAAAAGV
MAB_0984c|M.abscessus_ATCC_199 MTKPATRGRKTTRPSGDERIQAILATAEELLGKRPLADVSVDDLARGAGI
:: * :. .: ::* .:
Mflv_0240|M.gilvum_PYR-GCK SRATLHRHFAGRPALMAALEELAVAEMRDVLEDARLQEDSAIDALRRLVT
Mvan_0665|M.vanbaalenii_PYR-1 SRATLHRHFAGRVALMTALEELAITEMRTVLDTVQLHEGTPTAALRRLVS
MUL_0778|M.ulcerans_Agy99 SRATLHRYFAGRAALIDALEQLAFGQMREALKSARWQEGSATEELRRLVA
MMAR_2831|M.marinum_M SRATLHRHFAKRGALLEALDRLAISQLGEAMTISRCQEGTAAEALQRLVA
MAV_1333|M.avium_104 SRSTIYEYFSDKAAIVEACAEHASERFYREMAKAMDRGGTLEERLCAAAV
TH_4573|M.thermoresistible__bu SRGTVYRYFEDRTILIEAAIEYGAQKFYQEIAAAMAKKSTLAEQLGAMAE
Mb3185c|M.bovis_AF2122/97 EQPAIYKHFSAKRDILAALVRLAVEWPLELFGHITAMPVPAVVKLHRWLT
Rv3160c|M.tuberculosis_H37Rv EQPAIYKHFSAKRDILAALVRLAVEWPLELFGHITAMPVPAVVKLHRWLT
MSMEG_6223|M.smegmatis_MC2_155 GRSTVHRYYPERTDLLRALARHVHDLSNAAIERADPTSGPVDAALRRVVE
MAB_0984c|M.abscessus_ATCC_199 SRPTFYFYFSSKESVLLTLAERIIEEADANVASIDPAAMTSPAQYWRAVI
: :.: :: : :: : . . .
Mflv_0240|M.gilvum_PYR-GCK ACEP---VSPYLALLYSQSQELDFDSTLDA---WQEIDTAITDLFLRGQR
Mvan_0665|M.vanbaalenii_PYR-1 ACEP---VSPYLALLYTQSQEIDMDATLEA---WQAIDDEITALFVRGQR
MUL_0778|M.ulcerans_Agy99 ACES---VSGYLTLLYAYSQDSDTNELKQG---WLEIDSEIKELFLRGQR
MMAR_2831|M.marinum_M ACRP---VSGYLRLLYIRAQDFESDQLTEG---WAEIDAQLRQLFLRGQR
MAV_1333|M.avium_104 FVTQARRVIASEKYFDEDAISLL--LTKDAAVLLRECVEFFAPYLAAARL
TH_4573|M.thermoresistible__bu THAKILLDHRTRNRLMTDDAELMRHMIADADAAVRRTTEFLMPYVQQAKE
Mb3185c|M.bovis_AF2122/97 ESLDHLHASPYVLVSILITPDLHQESFVAERELVAEMERALVGLIETGQG
Rv3160c|M.tuberculosis_H37Rv ESLDHLHASPYVLVSILITPDLHQESFVAERELVAEMERALVGLIETGQG
MSMEG_6223|M.smegmatis_MC2_155 SQLD---LGPIVLFVYYEPSILADPELAAY---FDIGDEAIVEVLNRAST
MAB_0984c|M.abscessus_ATCC_199 KAYFDAFGSHRALTVALSSMQGTSPELDQR---WSEVTENWVANTTVGIE
.
Mflv_0240|M.gilvum_PYR-GCK DGDFRP---ELPAAWLTEALYGLIGGTAWSVRAG----------RAAARD
Mvan_0665|M.vanbaalenii_PYR-1 DGEFRP---ELTAAWLTEMFYSLVGGTAWSIRAG----------RAAARD
MUL_0778|M.ulcerans_Agy99 QGEFRP---DLAAGWLTEAFYSLVSGAGWSINTG----------RAAPRD
MMAR_2831|M.marinum_M SGEFRR---DLPTLWLNQAFFSLVAGAGRSANTG----------RIARSD
MAV_1333|M.avium_104 TGEVRKDL-DVEAA---GEWFARILFSLFSTPS-------PTLNLDDPDV
TH_4573|M.thermoresistible__bu RGEVGSGV-DVKAA---SEWLARIIYSFTTVNEG------LTFDMSKPAT
Mb3185c|M.bovis_AF2122/97 EGDVRAMH-PLSAARLVQALFDALALPEFAVSPDEIVEFAMTALLSDPDR
Rv3160c|M.tuberculosis_H37Rv EGDVRAMH-PLSAARLVQALFDALALPEFAVSPDEIVEFAMTALLSDPDR
MSMEG_6223|M.smegmatis_MC2_155 E---RP---EYPPGWARRVFWALMQAGYEAAKDG-----------MPRHQ
MAB_0984c|M.abscessus_ATCC_199 AERARGAAPSVVPARDIAIALNLINQAMMRATFTG------QQPAVDDGK
. :
Mflv_0240|M.gilvum_PYR-GCK FNRLILDLLLNGATPR-------------------------------
Mvan_0665|M.vanbaalenii_PYR-1 FDRLIIDLLLHGVTS--------------------------------
MUL_0778|M.ulcerans_Agy99 FAPMITELLLHGVSHSGQPSTNNHHAPERRRLGSEPMRPMINSRATR
MMAR_2831|M.marinum_M FTGMVTELLLRGARSS-------------------------------
MAV_1333|M.avium_104 TAEFVRAHVVRGFASERPRRR--------------------------
TH_4573|M.thermoresistible__bu VRRYVERFAVNGLR---------------------------------
Mb3185c|M.bovis_AF2122/97 LAEIRAAADALEIQTAPPDRGL-------------------------
Rv3160c|M.tuberculosis_H37Rv LAEIRAAADALEIQTAPPDRGL-------------------------
MSMEG_6223|M.smegmatis_MC2_155 IVDAIMTSLTSGIITLPRT----------------------------
MAB_0984c|M.abscessus_ATCC_199 VVDTLLHVWLNAIYGGVCANS--------------------------