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MYYRLMALDHERLLRAAAEFLGRRPNATQDEIAAAIGVSRATLHRYFAGRAALIDALEQLAFGQMREALK SARWQEGSATEELRRLVAACESVSGYLTLLYAYSQDSDTNELKQGWLEIDSEIKELFLRGQRQGEFRPDL AAGWLTEAFYSLVSGAGWSINTGRAAPRDFAPMITELLLHGVSHSGQPSTNNHHAPERRRLGSEPMRPMI NSRATR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0778 | - | - | 100% (217) | TetR family transcriptional regulator |
| M. ulcerans Agy99 | MUL_2922 | - | 2e-53 | 61.96% (163) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_0240 | - | 1e-59 | 62.92% (178) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1525c | - | 8e-05 | 29.66% (145) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1026 | - | 1e-116 | 97.63% (211) | TetR family transcriptional regulator |
| M. avium 104 | MAV_2463 | - | 5e-07 | 28.57% (175) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6223 | - | 2e-08 | 29.08% (141) | TetR family protein transcriptional repressor LfrR |
| M. thermoresistible (build 8) | TH_0276 | - | 2e-06 | 39.44% (71) | transcriptional regulator, TetR family protein |
| M. vanbaalenii PYR-1 | Mvan_0665 | - | 2e-59 | 63.48% (178) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_0778|M.ulcerans_Agy99 --------MMYYRLMALDHERLLRAAAEFLGRR--PNATQDEIAAAIGVS
MMAR_1026|M.marinum_M --------------MALDHERLLRAAAEFLGRR--PNATQDEIAAAIGVS
Mflv_0240|M.gilvum_PYR-GCK --------------MALSRDDLLRAAADFLGRR--PNATQDEIAAAVGVS
Mvan_0665|M.vanbaalenii_PYR-1 --------------MTATRDQLLRAAADFLGRR--PNATQDEIAAAIGVS
MSMEG_6223|M.smegmatis_MC2_155 ----MTSPSIESGARERTRRAILDAAMLVLADH--PTAALGDIAAAAGVG
MAV_2463|M.avium_104 --MTAVEDRPLRSDAARNVERILRAAREVYAELG-PDAPVEAVARRAGVG
TH_0276|M.thermoresistible__bu ---------MPDRIAASARERILTATAEVLGRAGMTKLSLSDVAQQAGVS
MAB_1525c|M.abscessus_ATCC_199 MSSSPSALSRVERKKREMRQEILDSAFACFAEQGYHATGVADIAGRIGIG
:* :: . :* *:.
MUL_0778|M.ulcerans_Agy99 RATLHRYFAGRAALIDALEQLAFGQMREALKSARW--------QEGSATE
MMAR_1026|M.marinum_M RATLHRYFAGRAALIDALEQLAFGQMREALKSARW--------QEGSATE
Mflv_0240|M.gilvum_PYR-GCK RATLHRHFAGRPALMAALEELAVAEMRDVLEDARL--------QEDSAID
Mvan_0665|M.vanbaalenii_PYR-1 RATLHRHFAGRVALMTALEELAITEMRTVLDTVQL--------HEGTPTA
MSMEG_6223|M.smegmatis_MC2_155 RSTVHRYYPERTDLLRALARHVHDLSNAAIERADP--------TSGPVDA
MAV_2463|M.avium_104 ERTLYRRFPAKADLVRAALDQSIAEDLTPVIDSAR--------HAKDPLH
TH_0276|M.thermoresistible__bu RPTLYRWFSGKEELLDAFAQWERQMYERALAEATAG------LPAEERLD
MAB_1525c|M.abscessus_ATCC_199 HGTFYRYFKSKRDIIEHVIDDVTGQIFEAIGAENAAGLADDIEQYRQQSV
. *.:* : : :: :
MUL_0778|M.ulcerans_Agy99 ELRRLVAACESVSGYLTLLYAYSQDSDTNELKQGWLEI---DSEIKELFL
MMAR_1026|M.marinum_M ALRRLVAACESVSGYLTLLYAYSQDSDTNELKQGWLEI---DSEIKELFL
Mflv_0240|M.gilvum_PYR-GCK ALRRLVTACEPVSPYLALLYSQSQELDFDSTLDAWQEI---DTAITDLFL
Mvan_0665|M.vanbaalenii_PYR-1 ALRRLVSACEPVSPYLALLYTQSQEIDMDATLEAWQAI---DDEITALFV
MSMEG_6223|M.smegmatis_MC2_155 ALRRVVESQLDLGPIVLFVYYEPSILADPELAAYFDIG---DEAIVEVLN
MAV_2463|M.avium_104 GLTRLVEAAISLGAREQNLLAAAHR-AGSLTSDISVSL---NEALGELVR
TH_0276|M.thermoresistible__bu AVLRVIVEYQQSYPGLRMVDIEPAHLIGRLS-AILPVM---RDRLERLCT
MAB_1525c|M.abscessus_ATCC_199 RIGAALAHLFRENPHLPLLLLEAGSVDSELRERVFGMLSTSDHLTEAYLR
: : : .
MUL_0778|M.ulcerans_Agy99 RGQRQGEFRPDLAAGWLTEAFYSLVSGAGWSINTGR--AAPRDFAPMITE
MMAR_1026|M.marinum_M RGQRQGEFRPDLAAGWLTEAFYSLVSGAGWSINTGR--AAPRDFAPMITE
Mflv_0240|M.gilvum_PYR-GCK RGQRDGDFRPELPAAWLTEALYGLIGGTAWSVRAGR--AAARDFNRLILD
Mvan_0665|M.vanbaalenii_PYR-1 RGQRDGEFRPELTAAWLTEMFYSLVGGTAWSIRAGR--AAARDFDRLIID
MSMEG_6223|M.smegmatis_MC2_155 RASTE---RPEYPPGWARRVFWALMQAGYEAAKDGM--PRHQIVDAIMTS
MAV_2463|M.avium_104 EGQRAGRIRADLVADDLPR-LVAMLYSVLSTMDAGS--EGWRRYVALVVD
TH_0276|M.thermoresistible__bu G--------PTASAAAATAVRVAVSHYLVQSDDAGD--FLAQLRHAVGLP
MAB_1525c|M.abscessus_ATCC_199 HGVEKGYLRADLDTEYTARAVTGMILANGLHASRGGEVQDTERFSAAVIA
. . .: * .
MUL_0778|M.ulcerans_Agy99 LLLHGVSHSGQPSTNNHHAPERRRLGSEPMRPMINSRATR
MMAR_1026|M.marinum_M LLLHGVSHSGQPNTNNHHAPERRRLGSEPTRPMINSRVSR
Mflv_0240|M.gilvum_PYR-GCK LLLNGATPR-------------------------------
Mvan_0665|M.vanbaalenii_PYR-1 LLLHGVTS--------------------------------
MSMEG_6223|M.smegmatis_MC2_155 LTSGIITLPRT-----------------------------
MAV_2463|M.avium_104 AISVDERRPLPPAAALRYASQPNSWPL-------------
TH_0276|M.thermoresistible__bu IAPGAVSAKTPLQPRRNP----------------------
MAB_1525c|M.abscessus_ATCC_199 LMYGGIGP--------------------------------