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MTSPSIESGARERTRRAILDAAMLVLADHPTAALGDIAAAAGVGRSTVHRYYPERTDLLRALARHVHDLS NAAIERADPTSGPVDAALRRVVESQLDLGPIVLFVYYEPSILADPELAAYFDIGDEAIVEVLNRASTERP EYPPGWARRVFWALMQAGYEAAKDGMPRHQIVDAIMTSLTSGIITLPRT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6223 | - | - | 100% (189) | TetR family protein transcriptional repressor LfrR |
| M. smegmatis MC2 155 | MSMEG_3425 | - | 1e-10 | 29.84% (191) | TetR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_2557 | - | 9e-07 | 37.93% (87) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3081 | - | 2e-05 | 32.97% (91) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0240 | - | 6e-10 | 30.86% (162) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3055 | - | 2e-05 | 32.97% (91) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_01733 | - | 1e-05 | 29.73% (111) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4546c | - | 5e-07 | 32.95% (88) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1026 | - | 3e-09 | 29.79% (141) | TetR family transcriptional regulator |
| M. avium 104 | MAV_5275 | - | 1e-06 | 32.31% (130) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0275 | - | 1e-06 | 32.79% (122) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_0778 | - | 9e-09 | 29.08% (141) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0665 | - | 7e-12 | 30.90% (178) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0240|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0665|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_1026|M.marinum_M --------------------------------------------------
MUL_0778|M.ulcerans_Agy99 --------------------------------------------------
Mb3081|M.bovis_AF2122/97 -------------------------------MSGAERLGDLPVFARQE-P
Rv3055|M.tuberculosis_H37Rv -------------------------------MSGAERLGDLPVFARQE-P
MSMEG_6223|M.smegmatis_MC2_155 ---------------------------------------------MTS-P
MAV_5275|M.avium_104 ----------------------------------------MEPSRRWG-D
MAB_4546c|M.abscessus_ATCC_199 ---------------------------------------MQPGVQECA-A
MLBr_01733|M.leprae_Br4923 MTRRSIHTRKPLKWSGCAGQHVRSGKVFDVGRISLSYPSMKPGVKIDARS
TH_0275|M.thermoresistible__bu -------------------------------------------VNQPTDQ
Mflv_0240|M.gilvum_PYR-GCK ------MALSRDDLLRAAADFLGRR--PNATQDEIAAAVGVSRATLHRHF
Mvan_0665|M.vanbaalenii_PYR-1 ------MTATRDQLLRAAADFLGRR--PNATQDEIAAAIGVSRATLHRHF
MMAR_1026|M.marinum_M ------MALDHERLLRAAAEFLGRR--PNATQDEIAAAIGVSRATLHRYF
MUL_0778|M.ulcerans_Agy99 MMYYRLMALDHERLLRAAAEFLGRR--PNATQDEIAAAIGVSRATLHRYF
Mb3081|M.bovis_AF2122/97 VPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLFRRF
Rv3055|M.tuberculosis_H37Rv VPERGDAARNRALLLEAARRLIARSGADAITMDDVAAAAGVGKGTLFRRF
MSMEG_6223|M.smegmatis_MC2_155 SIESGARERTRRAILDAAMLVLADH--PTAALGDIAAAAGVGRSTVHRYY
MAV_5275|M.avium_104 DRAILDDEEARRRILEAAGRCIVRRGNTQFRMGEVADEAGVSRSTVYRYF
MAB_4546c|M.abscessus_ATCC_199 GRWSGQRERRRAEFVDAALAAIAEHG-PQTSTEQIAVHLGVTRTKLYRHF
MLBr_01733|M.leprae_Br4923 ERWREHRKKVRGEIVDAAFRALDRLG-PEVSVREIAEEAGTAKPKIYRHF
TH_0275|M.thermoresistible__bu QAAPEEEASTRHRILEATAEVLSRAGKRKLSLSEVALQAGVSRPTLYRWF
: :: *: : ::* *. : .:.* :
Mflv_0240|M.gilvum_PYR-GCK AGR-PALMAALEELAVAEMRDVLEDAR--LQEDSAIDALRR-LVTACEPV
Mvan_0665|M.vanbaalenii_PYR-1 AGR-VALMTALEELAITEMRTVLDTVQ--LHEGTPTAALRR-LVSACEPV
MMAR_1026|M.marinum_M AGR-AALIDALEQLAFGQMREALKSAR--WQEGSATEALRR-LVAACESV
MUL_0778|M.ulcerans_Agy99 AGR-AALIDALEQLAFGQMREALKSAR--WQEGSATEELRR-LVAACESV
Mb3081|M.bovis_AF2122/97 GSR-AGLMMVLLDEDERASQQAFLFGP--PPLGPDAPPLDR-LIAFGRER
Rv3055|M.tuberculosis_H37Rv GSR-AGLMMVLLDEDERASQQAFLFGP--PPLGPDAPPLDR-LIAFGRER
MSMEG_6223|M.smegmatis_MC2_155 PER-TDLLRALARHVHDLSNAAIERAD--PTSGPVDAALRR-VVESQLDL
MAV_5275|M.avium_104 PGRDDVLLGLMLRRVDHALAESVRSLP--APEDPVRSVPQM-VLARVESV
MAB_4546c|M.abscessus_ATCC_199 TDA-ADLQRAVAQRASDMLIADLAPLW--EPDGSMAQIIEAGVGAHARFL
MLBr_01733|M.leprae_Br4923 TDK-SDLFEAIGIRLRDMLWAAIFPAID-LATDSAREIIRRSVDEYVSLV
TH_0275|M.thermoresistible__bu ASK-EDLLDAFGAYERQLFDTGISKATAGLRGNEKLDAALRFIVEYQHSY
* . . . :
Mflv_0240|M.gilvum_PYR-GCK SP---YLALLYSQSQELDFD---STLDAWQEIDTAITDLFLRGQRDGDFR
Mvan_0665|M.vanbaalenii_PYR-1 SP---YLALLYTQSQEIDMD---ATLEAWQAIDDEITALFVRGQRDGEFR
MMAR_1026|M.marinum_M SG---YLTLLYAYSQDSDTN---ELKQGWLEIDSEIKELFLRGQRQGEFR
MUL_0778|M.ulcerans_Agy99 SG---YLTLLYAYSQDSDTN---ELKQGWLEIDSEIKELFLRGQRQGEFR
Mb3081|M.bovis_AF2122/97 MR---FVHAHHQLLSEANRDPQTRHSAALSVLRTHLRVLLASAPTTG---
Rv3055|M.tuberculosis_H37Rv MR---FVHAHHQLLSEANRDPQTRHSAALSVLRTHLRVLLASAPTTG---
MSMEG_6223|M.smegmatis_MC2_155 GP---IVLFVYYEPSILADP---ELAAYFDIGDEAIVEVLNRASTER---
MAV_5275|M.avium_104 DGNPLNEALFAAESTAMASALQKGSEPLVELLLRHYGPLLERWKAAGLLY
MAB_4546c|M.abscessus_ATCC_199 VGHRNLYRYLAHCSMAENSDGPDAITDIKLAVGTHLGQVFALY--LGAFG
MLBr_01733|M.leprae_Br4923 DKHPNVLRVFIQGRFSAQSEATVRTLDEGREITLTMAEMFNNELREMELN
TH_0275|M.thermoresistible__bu SG----VRLVDIEPEVVIAQ----LSQVIPVMRARLQRLLPGANGAVKAA
::
Mflv_0240|M.gilvum_PYR-GCK PELPAAWLTEALYG---LIGGTAWSVRAGRAAAR-----DFNRLILDLLL
Mvan_0665|M.vanbaalenii_PYR-1 PELTAAWLTEMFYS---LVGGTAWSIRAGRAAAR-----DFDRLIIDLLL
MMAR_1026|M.marinum_M PDLAAGWLTEAFYS---LVSGAGWSINTGRAAPR-----DFAPMITELLL
MUL_0778|M.ulcerans_Agy99 PDLAAGWLTEAFYS---LVSGAGWSINTGRAAPR-----DFAPMITELLL
Mb3081|M.bovis_AF2122/97 -DLDAQTDALLALL---DVDYVEHQLNAGGHTLQ-----TLGDAWESLAR
Rv3055|M.tuberculosis_H37Rv -DLDAQTDALLALL---DVDYVEHQLNAGGHTLQ-----TLGDAWESLAR
MSMEG_6223|M.smegmatis_MC2_155 PEYPPGWARRVFWA---LMQAGYEAAKDGMPRHQ-----IVDAIMTSLTS
MAV_5275|M.avium_104 PDVDFRSVVQWLHTATLFLLAPSWRYRPHADKRR-----FVEQFVVRALV
MAB_4546c|M.abscessus_ATCC_199 AGVESDILAMGIVG-MVETATSHWLDNPGTTSQE-----RLIADQVRWIW
MLBr_01733|M.leprae_Br4923 RAASELAAFAAFGS---VASATEWWLGPEPDSPRRMPREQFVAHLTIIMM
TH_0275|M.thermoresistible__bu TAIRVAVSHYIVRS-----DDDDQFLAQLRHAVG------IKAPAGEPAP
.
Mflv_0240|M.gilvum_PYR-GCK NGATPR----------------------------------
Mvan_0665|M.vanbaalenii_PYR-1 HGVTS-----------------------------------
MMAR_1026|M.marinum_M HGVSHSGQPNTNNHHAPERRRLGSEPTRPMINSRVSR---
MUL_0778|M.ulcerans_Agy99 HGVSHSGQPSTNNHHAPERRRLGSEPMRPMINSRATR---
Mb3081|M.bovis_AF2122/97 KLCGR-----------------------------------
Rv3055|M.tuberculosis_H37Rv KLCGR-----------------------------------
MSMEG_6223|M.smegmatis_MC2_155 GIITLPRT--------------------------------
MAV_5275|M.avium_104 PQIRQ-----------------------------------
MAB_4546c|M.abscessus_ATCC_199 LLLDDTLRAEGIYVNPNEPLPPPDEIARTADSYRDPSRLR
MLBr_01733|M.leprae_Br4923 AVIVGTAETLGISMNPDRPIHDAVPLDRSAS---------
TH_0275|M.thermoresistible__bu AR--------------------------------------