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LCDSLTRWTVRSDEVYGQHAGVCESLCGEGDSTTVIARDEAEAQTSSAPDQVGSVRWKPVSSTHRCGWRS KWAPLLVIAVMLGACGGLPPAVTPPGTTDNSDLKTRSQRVLDGAVNPDEPGCSAAVGVEGVVMWTGVLGI ADLATNKKVTKDTVFDIGSVSKQFTATAVLLLINEGRLTLDDPLAHYVPDLPDWSSAVTVAQLMHHTSGI PDYTGLLEAQGYQMSDRTTQAQALAAIQGAPELEFKPGTRFEYSNSNYLLLAEIVRLVSGKSLPDFLSIE IFRPLDLAMVVDPISADPDEAVSYGEGDTGNPPQFPVLHSGWEQVGDGAIQTTPSQLVLWADNYRTGKVG GQKLLDEQLAGAVETEPGSGDRYGAGIFSRANGTLDHDGSWAGFVTDFRISSDRRTSVAVSCNMEGQDPE SLADAIGRLWM
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2827 | - | - | 100% (431) | lipoprotein |
| M. marinum M | MMAR_0696 | lpqK | 2e-18 | 27.73% (321) | lipoprotein, LpqK |
| M. marinum M | MMAR_3399 | - | 2e-16 | 28.72% (195) | hypothetical protein MMAR_3399 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1957 | - | 1e-140 | 67.23% (357) | lipoprotein |
| M. gilvum PYR-GCK | Mflv_0495 | - | 2e-18 | 29.67% (246) | beta-lactamase |
| M. tuberculosis H37Rv | Rv1922 | - | 1e-140 | 67.23% (357) | lipoprotein |
| M. leprae Br4923 | MLBr_00119 | lipE | 4e-10 | 31.21% (141) | putative hydrolase |
| M. abscessus ATCC 19977 | MAB_0330 | - | 7e-29 | 30.97% (352) | Beta-lactamase |
| M. avium 104 | MAV_3991 | - | 9e-16 | 28.30% (212) | beta-lactamase |
| M. smegmatis MC2 155 | MSMEG_1586 | - | 6e-30 | 30.96% (323) | beta-lactamase |
| M. thermoresistible (build 8) | TH_3520 | - | 3e-27 | 29.58% (311) | PUTATIVE beta-lactamase |
| M. ulcerans Agy99 | MUL_3735 | lipP | 4e-12 | 30.18% (169) | esterase/lipase LipP |
| M. vanbaalenii PYR-1 | Mvan_3027 | - | 4e-31 | 31.92% (354) | Serine-type D-Ala-D-Ala carboxypeptidase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0495|M.gilvum_PYR-GCK ------------------MTRSSTRLRRLGAAGAVVLALGACGDRPEPPG
MAV_3991|M.avium_104 -----------------------------------MLTLVAASSTGRVVH
Mb1957|M.bovis_AF2122/97 -----------------------------MDST----------VTASIRR
Rv1922|M.tuberculosis_H37Rv -----------------------------MDST----------VTASIRR
MMAR_2827|M.marinum_M MCDSLTRWTVRSDEVYGQHAGVCESLCGEGDSTTVIARDEAEAQTSSAPD
MSMEG_1586|M.smegmatis_MC2_155 -----------------------------------MMS-AWPLVPGFVRA
Mvan_3027|M.vanbaalenii_PYR-1 -------------------MADENGRRDSAHTLGAMITRALPIVFAMVLA
MAB_0330|M.abscessus_ATCC_1997 --------------------------------MPELSTRCFDESSLMRRI
TH_3520|M.thermoresistible__bu --------------------------------------------MRAVRT
MUL_3735|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00119|M.leprae_Br4923 -------------------------------------------MTSDGK-
Mflv_0495|M.gilvum_PYR-GCK TSAV-----------------------RPPATPTRVLPSPPPPVPEVT-P
MAV_3991|M.avium_104 TS--------------------------PSEAPPASMTPHASLVPESTSP
Mb1957|M.bovis_AF2122/97 MLG---------------------LLAATLLLGGCTGQHTTRTAASTTYT
Rv1922|M.tuberculosis_H37Rv MLG---------------------LLAATLLLGGCTGQHTTRTAASTTYT
MMAR_2827|M.marinum_M QVGSVRWKPVSSTHRCGWRSKWAPLLVIAVMLGACGGLPPAVTPPGTTDN
MSMEG_1586|M.smegmatis_MC2_155 ATG------------------------AVIAAITFVAASACATAPA---A
Mvan_3027|M.vanbaalenii_PYR-1 LTAC---------------------GESVDTTQTTGSRNPAVTAPATTMA
MAB_0330|M.abscessus_ATCC_1997 LAVV---------------------LTIALLVSACGKHSAIVVAEL---D
TH_3520|M.thermoresistible__bu LAA-------------------------LLLAVFAVSAGPSAAGQP----
MUL_3735|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00119|M.leprae_Br4923 ----------------------------IRVPTDLDAVTAIGDEDHSDID
Mflv_0495|M.gilvum_PYR-GCK TGDFSAVARLVEDAIAARRLPGAVVQVGHAGKVVFRRAFGV--RKLESEP
MAV_3991|M.avium_104 AEDFTTISKLVNDAIAARGLPGAVVMVGHGGKVVFHQAYGS--RKLAGEP
Mb1957|M.bovis_AF2122/97 PHIKASSQDVLDGAINAD-EPGCSAAVGVEGKVIWSGVRGI--ADLASG-
Rv1922|M.tuberculosis_H37Rv PHIKASSQDVLDGAINAD-EPGCSAAVGVEGKVIWSGVRGI--ADLASG-
MMAR_2827|M.marinum_M SDLKTRSQRVLDGAVNPD-EPGCSAAVGVEGVVMWTGVLGI--ADLATN-
MSMEG_1586|M.smegmatis_MC2_155 PPIAAQLDDAVGKVMADLSIPGAVVGFWGP-DVTYVRAFGV--ADTATR-
Mvan_3027|M.vanbaalenii_PYR-1 AEVTDRLDDAVERVMTEAGIPGAIVGIWGP-GGDYVRAFGV--ADTKTR-
MAB_0330|M.abscessus_ATCC_1997 PQTTAKLDSAINEILTSAAVPGAIVGVWGP-KGQYVRTFGV--ANTATR-
TH_3520|M.thermoresistible__bu PDLAAALDRAIELRLDQMGVPGAIVSLSIPGKIEYTRAFGV--GDTATG-
MUL_3735|M.ulcerans_Agy99 ------------------MEVGAAVAVWVDGDLVVNLWGGS--ADAAGT-
MLBr_00119|M.leprae_Br4923 SAAVERIWQATRHWYQAGMHPAIQLCIRQHGRVVLNRAIGHGWGNAPTDP
. . * .
Mflv_0495|M.gilvum_PYR-GCK GLDGAPAPAEPMTEDTVFDIASLTKSLATATAVMQLHEQGRVRIDEPVQT
MAV_3991|M.avium_104 GLDGAPAPAEPMTEDTIFDLASLTKCLATAVAVMQLYEQGKVAFDDPVQK
Mb1957|M.bovis_AF2122/97 ---------AKITTDTVFDIASVSKQFT-ATAILLLVEAGKLTLDDPISQ
Rv1922|M.tuberculosis_H37Rv ---------AKITTDTVFDIASVSKQFT-ATAILLLVEAGKLTLDDPISQ
MMAR_2827|M.marinum_M ---------KKVTKDTVFDIGSVSKQFT-ATAVLLLINEGRLTLDDPLAH
MSMEG_1586|M.smegmatis_MC2_155 ---------APMQADMYTRIGSLTKTFT-ITALLTLIDQGKAGLDDPISM
Mvan_3027|M.vanbaalenii_PYR-1 ---------APMKTDFYSRIGSLTKTFT-VTAVLLLADQGRLGLDDPIAG
MAB_0330|M.abscessus_ATCC_1997 ---------APLRPDFYHRIGSVTKTFT-VTAVLQLVDEGKVELDDPIAK
TH_3520|M.thermoresistible__bu ---------TPMLVDNHHRIGSVTKTFI-GTAILQLADQGRIRLSDPISR
MUL_3735|M.ulcerans_Agy99 ---------RPWRQDTLTTVLSGSKALT-ATCVHQLADRGELNLHAPVAR
MLBr_00119|M.leprae_Br4923 ----HDAEKIPVTTDTPFCAYSAAKAIT-ATVVHMLVERGHFSLDDRVCE
* * :* : . : * : *. : :
Mflv_0495|M.gilvum_PYR-GCK YLPGFNPA-GDPRRAAVTVRMLLTHTSGIAGDLSLDGPWGLAGP------
MAV_3991|M.avium_104 YLPAFNTT-NDPQRAKVTIRMLLTNTSGEGIDVSLRDPWGLAGP------
Mb1957|M.bovis_AF2122/97 YVPELPDW-AQTVTVEQLMHQTSGIPDYVALLAARGYQVSDRTI------
Rv1922|M.tuberculosis_H37Rv YVPELPDW-AQTVTVEQLMHQTSGIPDYVALLAARGYQVSDRTI------
MMAR_2827|M.marinum_M YVPDLPDW-SSAVTVAQLMHHTSGIPDYTGLLEAQGYQMSDRTT------
MSMEG_1586|M.smegmatis_MC2_155 YVADVPS--GDTITLRHLAQMQSGLVTYDGVPEFEAAFLADPQR-----T
Mvan_3027|M.vanbaalenii_PYR-1 YVDGVPG--GDAITLRQLARMQSGLPDYTANPEFVPTVIADPGR-----A
MAB_0330|M.abscessus_ATCC_1997 YVDKVPN--GNKITLRELARMQSGLFNYSMSLAFSRDLEADPRR-----Q
TH_3520|M.thermoresistible__bu YVEGVPS--GDVITLDMLARMRSGLADYTETDEFVERLYRESPSGPDAFA
MUL_3735|M.ulcerans_Agy99 YWPEFRQAGKEAITVAMVLSHRSGVIGPNARMSWQQVTDWDFVC------
MLBr_00119|M.leprae_Br4923 YLPTYTSYGKHRTTIRHVLTHSAGVPFPTGPRPDVTRADDHAYA------
*
Mflv_0495|M.gilvum_PYR-GCK -DKADGVRRALGAWVVSDPGEGFHYSDINF-IILGALVEKITGEPEDSYV
MAV_3991|M.avium_104 -DKAEGIHRALTTPLQSAPAGEFRYSDINY-LLLGALLEKITGEDEDDYV
Mb1957|M.bovis_AF2122/97 -EAEARQALAAAPELQFKPGTRFDYSNSNY-LLLGEIVHRASGQPLPEFL
Rv1922|M.tuberculosis_H37Rv -EAEARQALAAAPELQFKPGTRFDYSNSNY-LLLGEIVHRASGQPLPEFL
MMAR_2827|M.marinum_M -QAQALAAIQGAPELEFKPGTRFEYSNSNY-LLLAEIVRLVSGKSLPDFL
MSMEG_1586|M.smegmatis_MC2_155 FTPQQLLGYALDKPLQFPPGTQYDYCNTNT-VLLGLVVEKLSGQSLADYV
Mvan_3027|M.vanbaalenii_PYR-1 FAPTEMLEFAFSQPPMFAPGDGYHYSNTNT-VLLGLVVEKVSGQSLGDYI
MAB_0330|M.abscessus_ATCC_1997 YSTHELLDYAFAQPSNFVPGQGYEYSNTNA-VLLGQVVEKVSGQTLPAFV
TH_3520|M.thermoresistible__bu VTPRELVESAFARPLNFAPGSEFEYSNTNT-VLLGMVVERVSGVPLARYL
MUL_3735|M.ulcerans_Agy99 ------EQLALAEP-RWEPGSAQGYHMTTFGFILGEVFRRITGRTVGQYL
MLBr_00119|M.leprae_Br4923 ------QQKLSELRPFYRPGLVHIYHALTWGPLMREIIWTATGKEIRDIL
*. * . :: :. :* :
Mflv_0495|M.gilvum_PYR-GCK DRNVFAPLKMSETR----------YLPVTKVCGPHRVRGTAIAADPHGQA
MAV_3991|M.avium_104 QHHVFGPLGMHDTR----------YLPPAKACGPHIIRGAAIAWAPNGEP
Mb1957|M.bovis_AF2122/97 SAEIFQPLGLAMVV----------DPVG---KVPNKAVSYEKGTGGNR--
Rv1922|M.tuberculosis_H37Rv SAEIFQPLGLAMVV----------DPVG---KVPNKAVSYEKGTGGNR--
MMAR_2827|M.marinum_M SIEIFRPLDLAMVV----------DPIS---ADPDEAVSYGEGDTGNP--
MSMEG_1586|M.smegmatis_MC2_155 RQHILVPLKLTHTS----------IPTSPAFPEPHPQGYTVLDGTPR---
Mvan_3027|M.vanbaalenii_PYR-1 RRHISAPLGMAETS----------FPTDATFPGPHATGYTVQPPDDRE--
MAB_0330|M.abscessus_ATCC_1997 QEHITGPLGMRRTS----------FPETSAIADPHARGYTQLTPTGSL--
TH_3520|M.thermoresistible__bu QDNIFGPVGLTQTS----------YPADGRLPAPYTHGYNQ-GPDGAI--
MUL_3735|M.ulcerans_Agy99 RTEIAEPIGADVHIG---LSPFDQSRCAERVNKPHARDLLADVQAPSD--
MLBr_00119|M.leprae_Br4923 AAEILDPLGFRWTNFGVAEEDVPLVALSHATGRPLPPIIAAIFRKAIG--
.: *: *
Mflv_0495|M.gilvum_PYR-GCK VDNCPDGTWNIDLLERIAPTALDEDT---PGLNPDYGYPLRGTVHDPTAR
MAV_3991|M.avium_104 MTECPEWTWRTTLLPRIAPTARDEESRDDPSKNPDYYALLRGTVHDPTAR
Mb1957|M.bovis_AF2122/97 -------------------------------------------SEYRVGN
Rv1922|M.tuberculosis_H37Rv -------------------------------------------SEYRVGN
MMAR_2827|M.marinum_M -------------------------------------------PQFPVLH
MSMEG_1586|M.smegmatis_MC2_155 --------------------------------------------VTTDWN
Mvan_3027|M.vanbaalenii_PYR-1 -------------------------------------------MTATDWN
MAB_0330|M.abscessus_ATCC_1997 -------------------------------------------VDSTDWN
TH_3520|M.thermoresistible__bu -------------------------------------------VDTTLWN
MUL_3735|M.ulcerans_Agy99 ------------------PTSLDDHPKAGLSIAMGFAPDDELGSNDLHLW
MLBr_00119|M.leprae_Br4923 ------------------------------GTVHEVIPYTNTPPFLTTIV
Mflv_0495|M.gilvum_PYR-GCK RMGGVAGSAGVFTTVHDMGRFAQALLDRVAGRPSPFPLSQAGARMMTTPQ
MAV_3991|M.avium_104 RMGGVAGNAGVFSTAHDVGVYAQALLDRLAGRPSDFPLQQGTVELMTTPQ
Mb1957|M.bovis_AF2122/97 PAWEQIGDGGIQTTPSQLARWADNYRTGSVGGLKLLEAQLAGAVETEPGG
Rv1922|M.tuberculosis_H37Rv PAWEQIGDGGIQTTPSQLARWADNYRTGSVGGLKLLEAQLAGAVETEPGG
MMAR_2827|M.marinum_M SGWEQVGDGAIQTTPSQLVLWADNYRTGKVGGQKLLDEQLAGAVETEPGS
MSMEG_1586|M.smegmatis_MC2_155 PSWAWSN-GNMISTLDDMRVWAQKLSSGELLSENLRDERFRTALPMSENA
Mvan_3027|M.vanbaalenii_PYR-1 LSWSWAA-GNMVSTLHDLRIWAPALVTGTLLSRQMQQQRLQMVESSGQPA
MAB_0330|M.abscessus_ATCC_1997 PSWASWA-GAMISTLDDLRIWVPALATGVLLKPDSQQQRLQTVAMPPVPD
TH_3520|M.thermoresistible__bu PAWADAA-GKIVSNVHDMRTWARALGSGALLRPDTHAERIHGG--SSVVP
MUL_3735|M.ulcerans_Agy99 RQLEFPGTNAQVSALGLATFYNALAQEKLLSREHMDLVRVSQGGFDTDLV
MLBr_00119|M.leprae_Br4923 PSSNTVSTANELSRFAEIWLRGGELDGIRVLRSETLLGAVAECRRLRPDF
:
Mflv_0495|M.gilvum_PYR-GCK QP-----------------AP------GRDLRGFGWDIDTAHSGPRGSVF
MAV_3991|M.avium_104 QPGHDPRQLEAANRAARSGTPNYPAIKGQNLFGFGWDIDTGYSRPRGRVF
Mb1957|M.bovis_AF2122/97 GD------------------------------RYGAGIVSRADGTLD---
Rv1922|M.tuberculosis_H37Rv GD------------------------------RYGAGIVSRADGTLD---
MMAR_2827|M.marinum_M GD------------------------------RYGAGIFSRANGTLD---
MSMEG_1586|M.smegmatis_MC2_155 --------------------------------KYGVGAFD-TNGWIG---
Mvan_3027|M.vanbaalenii_PYR-1 PE------------------------------EYGLGMFN-VAGWIG---
MAB_0330|M.abscessus_ATCC_1997 DI------------------------------RYGLGIFD-ARGWIG---
TH_3520|M.thermoresistible__bu GV------------------------------DYSFAIFN-AQGWLG---
MUL_3735|M.ulcerans_Agy99 LG--------------------------PRVADHGWGLGYMLNQRAVNGP
MLBr_00119|M.leprae_Br4923 VVG-----------------------LMPARWGTGFILGTNKFGPFGRN-
.
Mflv_0495|M.gilvum_PYR-GCK PVGSFGHTGFTGVSVWLDPESDTYVVILGNVIHQRGGPPITPLSGAVATE
MAV_3991|M.avium_104 PIGSFGNTGFTGTTLWMDPGSDTYVILLSNSIHLRGSPPISNLRGDVATA
Mb1957|M.bovis_AF2122/97 --HAGAWAGFVTAFHISSDRRTSVAISCNTDKPDP-----VAMADALGRL
Rv1922|M.tuberculosis_H37Rv --HAGAWAGFVTAFHISSDRRTSVAISCNTDKPDP-----VAMADALGRL
MMAR_2827|M.marinum_M --HDGSWAGFVTDFRISSDRRTSVAVSCNMEGQDP-----ESLADAIGRL
MSMEG_1586|M.smegmatis_MC2_155 --HSGITPGFETVVVGLPEAQSTLVVFVNTDVPH---EVGTAVATAVTGV
Mvan_3027|M.vanbaalenii_PYR-1 --HNGSVPGYQTVSVYLPERQTALVILTNTDIAFRGAEPGTLLARAVTTE
MAB_0330|M.abscessus_ATCC_1997 --HSGSIPGYQTLAIYSPAEQTTVVALLNTDVAKQPAQPSTLFGTAITKV
TH_3520|M.thermoresistible__bu --HNGDIPGYATVVVYLPERDATLVVFVNSDVPEP--HSAGQIAYVVTEM
MUL_3735|M.ulcerans_Agy99 NQKIFGHGGLGGSFGFVDLEHRIGYAYVMNRFDAS-KANADPRSVALSNE
MLBr_00119|M.leprae_Br4923 APAAFGHLGLVNIAIWADPQRSMAAGLISSGKPGQ--DPNAGRYGALMNT
* :
Mflv_0495|M.gilvum_PYR-GCK AARALHLYGS------------
MAV_3991|M.avium_104 AARALHLYGAAPP---------
Mb1957|M.bovis_AF2122/97 WM--------------------
Rv1922|M.tuberculosis_H37Rv WM--------------------
MMAR_2827|M.marinum_M WM--------------------
MSMEG_1586|M.smegmatis_MC2_155 VTPDNVYR--------------
Mvan_3027|M.vanbaalenii_PYR-1 LTPDHVYTLS------------
MAB_0330|M.abscessus_ATCC_1997 ISPDHVFLLENAIPQPR-----
TH_3520|M.thermoresistible__bu VTPEHIYELGPQPPQMLDEPAA
MUL_3735|M.ulcerans_Agy99 VYAALDVAAD------------
MLBr_00119|M.leprae_Br4923 ITAEIPVH--------------