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VTAPASPPAKGSRDSPAGRQRAGGQPEGGELGVSALVSIGIGGMVGGGIFSVLGLTVQIADAGAYLSFVA GGVIAALTGRSYSLLSVRIRSRGGTAFFLDKCFGTAIGGPLNVLLWLSYFVMLGLYAVAFGSYGAVLLGA DPDGPWRRVLASAVVVAFAALNLAGAQIVGRAESFLVYGKLAILLLFCVAGLAFVDGSRVSPAHYPSFGV IVYAGALIFLGYEGFELIANAAEDARNPRRSLPLAYLISIGVVIVLYVLVAFVAVGNLDVAQIDHDRDYA LAAAARPFLGSAGFELIGIAAVISTASAINATLYGTGKFTYLMARNGELPAALGKPVWDRPIGGLLATTA GTLVVVNAVDIEGISLMGSAGFLLIFAAVNLAVLRLRITRLTRVLAVTGAVACVASFAAMTVYAAATTPA HLWVLGGFLVGAIVVEGLVRLRGRHVSHPPMRPEH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2579 | potE | - | 100% (455) | amino acid transporter PotE |
| M. marinum M | MMAR_3621 | rocE | 9e-30 | 27.45% (470) | cationic amino acid transport integral membrane protein RocE |
| M. marinum M | MMAR_2407 | rocE_1 | 6e-29 | 26.17% (447) | cationic amino acid transport integral membrane protein, |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2347c | rocE | 2e-27 | 25.90% (444) | cationic amino acid transport integral membrane protein RocE |
| M. gilvum PYR-GCK | Mflv_0187 | - | 6e-26 | 26.89% (383) | amino acid permease-associated region |
| M. tuberculosis H37Rv | Rv2320c | rocE | 2e-27 | 25.90% (444) | cationic amino acid transport integral membrane protein RocE |
| M. leprae Br4923 | MLBr_01974 | - | 7e-20 | 24.63% (402) | putative permease |
| M. abscessus ATCC 19977 | MAB_3842 | - | 2e-27 | 25.89% (479) | cationic amino acid transport integral membrane protein |
| M. avium 104 | MAV_2087 | - | 4e-25 | 25.00% (428) | amino acid transporter |
| M. smegmatis MC2 155 | MSMEG_1412 | - | 2e-26 | 24.53% (428) | amino acid permease |
| M. thermoresistible (build 8) | TH_4382 | - | 6e-21 | 28.68% (401) | PUTATIVE amino acid permease-associated region |
| M. ulcerans Agy99 | MUL_3182 | potE | 0.0 | 98.33% (419) | amino acid transporter PotE |
| M. vanbaalenii PYR-1 | Mvan_0718 | - | 4e-29 | 27.65% (405) | amino acid permease-associated region |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2347c|M.bovis_AF2122/97 --------------------------------------------------
Rv2320c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2087|M.avium_104 --------------------------------------------------
MAB_3842|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_1412|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0187|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0718|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_2579|M.marinum_M --------------------------------------------------
MUL_3182|M.ulcerans_Agy99 --------------------------------------------------
TH_4382|M.thermoresistible__bu --------------------------------------------------
MLBr_01974|M.leprae_Br4923 MFLSADVSCIEIVDINCSELRNDRRIPPQLALFCTNAANKAESAVTSHGQ
Mb2347c|M.bovis_AF2122/97 ---------------------------MPTTSMSLRELMLRRRPVSGAPV
Rv2320c|M.tuberculosis_H37Rv ---------------------------MPTTSMSLRELMLRRRPVSGAPV
MAV_2087|M.avium_104 -------------------------------------------------M
MAB_3842|M.abscessus_ATCC_1997 ---------------------------MAPSSPSLAQQLLRRRPTSGAPT
MSMEG_1412|M.smegmatis_MC2_155 ---------------------------MSAPPTSMAGQMMRRRPVIGAPV
Mflv_0187|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0718|M.vanbaalenii_PYR-1 -------------------------------------------------M
MMAR_2579|M.marinum_M -------------------------------MTAPASPPAKGSRDSPAGR
MUL_3182|M.ulcerans_Agy99 --------------------------------------------------
TH_4382|M.thermoresistible__bu ---------------------------------------------MSGTR
MLBr_01974|M.leprae_Br4923 LPIMANRRWAPHTRRQSGRATSTCSSLMRFSASESRAHSRFECYTLVRWS
Mb2347c|M.bovis_AF2122/97 ASGASGNLKRSFGTFQLTMFGVGATIGTGIFFVLAQAVPEAGPGVIVSFI
Rv2320c|M.tuberculosis_H37Rv ASGASGNLKRSFGTFQLTMFGVGATIGTGIFFVLAQAVPEAGPGVIVSFI
MAV_2087|M.avium_104 APGTADHLRRGIGTFQLTMFGVGSTIGTGIFFVMSQAVPEAGPAVIVSFL
MAB_3842|M.abscessus_ATCC_1997 AHGAGGHLKQSMGTFQLTMIGVGATVGTGIFFILAESVPKAGPAVMASFL
MSMEG_1412|M.smegmatis_MC2_155 AHGASDHLKRSIGTFQLTLFGVGATVGTGIFLVLQEAVPEAGPAVLVSFV
Mflv_0187|M.gilvum_PYR-GCK -------MRRRLGTFDTVTLGLGSMIGAGIFVALAPAAAAAGTGLLVGLA
Mvan_0718|M.vanbaalenii_PYR-1 SSPGGSTLDRRLGVFDTVTIGLGSMIGAGIFVALAPAAAAAGSGLLIGLA
MMAR_2579|M.marinum_M QRAGGQPEGGELGVSALVSIGIGGMVGGGIFSVLGLTVQIADAGAYLSFV
MUL_3182|M.ulcerans_Agy99 -----------------MSIGIGGMVGGGIFSVLGLTVQIADAGAYLSFV
TH_4382|M.thermoresistible__bu TEQAQPELRRVLGPGLLLLFIVGDILGTGIYALVGDVAGEVGGAAWLPFL
MLBr_01974|M.leprae_Br4923 IRGQGGRAISKLGFWSVVMLGINSIIGAGIFMTPGEVIKIAGPFAPIAYT
: :. :* **: ..
Mb2347c|M.bovis_AF2122/97 IAGIAAGLAAICYAELASAVPISGSAYSYAYTTLGEAVAMVVAACLLLEY
Rv2320c|M.tuberculosis_H37Rv IAGIAAGLAAICYAELASAVPISGSAYSYAYTTLGEAVAMVVAACLLLEY
MAV_2087|M.avium_104 LAGVAAGLAAVCYAELASAVPVSGSSYSYAYTTLGEVVAMGVAACLLLEY
MAB_3842|M.abscessus_ATCC_1997 VAGLAAGLAALCYAELASAVPVSGSSFSYAYTTLGELAAMVVAACLLLEY
MSMEG_1412|M.smegmatis_MC2_155 LAGVAAGLSALCYAEMASAVPVSGSTYSYAYTTMGEFVAMGVAACLLLEY
Mflv_0187|M.gilvum_PYR-GCK VAALIAVCNAMSSARLAARYPESGGTYVYGRERLGPFWGHTAGWSFIVGK
Mvan_0718|M.vanbaalenii_PYR-1 VAAVVAVCNAMSSARLAARYPQSGGTYVYGRERLGPFWGHAAGWSFIVGK
MMAR_2579|M.marinum_M AGGVIAALTGRSYSLLSVRIRSRGGTAFFLDKCFGTAIGGPLNVLLWLSY
MUL_3182|M.ulcerans_Agy99 AGGVIAALTGRSYSLLSVRIRSRGGTAFFLDKCFGTAIGGPLNVLLWLSY
TH_4382|M.thermoresistible__bu IAFLIATVTAFSYLELVTKYPQAAGAALYVHKAFGIQFVTFLVAFIVMCS
MLBr_01974|M.leprae_Br4923 LAGIFAAVLAIVFATAAKYVKTNGSSYAYTTAAFGHRIGIYVGVTHAITA
. : * . ..: : :* :
Mb2347c|M.bovis_AF2122/97 GVATAAVAVGWSGYVNKLLSNLFGFQMPHVLSAAPWDTHP-----GWVNL
Rv2320c|M.tuberculosis_H37Rv GVATAAVAVGWSGYVNKLLSNLFGFQMPHVLSAAPWDTHP-----GWVNL
MAV_2087|M.avium_104 GVATAAVSVNWSGYLNKLLSNVVGFQLPHALSAAPWDAQP-----GYVNL
MAB_3842|M.abscessus_ATCC_1997 GVSAAAVAVGWSQYLDKLLVNLFGWHLPHAISAAPWDSADPAAPHPWLNL
MSMEG_1412|M.smegmatis_MC2_155 GVSMSATSIGWGGYLNQLLDDVFGFRIPQALTSAPWGENP-----GIMNL
Mflv_0187|M.gilvum_PYR-GCK TASCAAMALTVGYYVWPAYANAVAVGSVVALTAVSY--------------
Mvan_0718|M.vanbaalenii_PYR-1 TASCAAMALTVGFYAWPEYANAVAVASVVALTAVGY--------------
MMAR_2579|M.marinum_M FVMLGLYAVAFGSYGAVLLGADPDGPWRRVLASAVVVAFA----------
MUL_3182|M.ulcerans_Agy99 FVMLGLYAVAFGSYGAVLLGADPDGPWRRVLASAVVVAFA----------
TH_4382|M.thermoresistible__bu GITSASTASRFFAANLEVGLGQEWGRLGVAGVALLFMALL----------
MLBr_01974|M.leprae_Br4923 SIAWGVLASSFVSTLLRVAFPEKIWADNDELISVKTLTFL----------
. : :
Mb2347c|M.bovis_AF2122/97 PAVILIGLCALLLIRGASESARVNAIMVLIKLGVLGMFMIIAFS------
Rv2320c|M.tuberculosis_H37Rv PAVILIGLCALLLIRGASESARVNAIMVLIKLGVLGMFMIIAFS------
MAV_2087|M.avium_104 PAVMLIGMCALLLIRGASESAKVNAIMVMVKLGVLVVFGILAFT------
MAB_3842|M.abscessus_ATCC_1997 PAVLLIIMCAILLIRGTSESALVNTVMVLLKLAVLSVFAIIAFT------
MSMEG_1412|M.smegmatis_MC2_155 TATLLIVMCGLLLIRGASESALVNTIMVIIKLAVLALFVAVAFT------
Mflv_0187|M.gilvum_PYR-GCK --------------AGVQRSATLTRVIVALVLGVLAMVVVVVFGSG----
Mvan_0718|M.vanbaalenii_PYR-1 --------------AGVQRSAALTRIIVALVLAVLAMVVVVLLGFG----
MMAR_2579|M.marinum_M ----------ALNLAGAQIVGRAESFLVYGKLAILLLFCVAGLA------
MUL_3182|M.ulcerans_Agy99 ----------ALNLAGAQIVGRAESFLVYGKLAILLLFCVAGLA------
TH_4382|M.thermoresistible__bu ---------AMVNLRGVGESVRLNVLLTIVEISGLLLVIFVGLWAFTGGG
MLBr_01974|M.leprae_Br4923 ---VFIAVLLAINIFGNLVIRWANGISALGKIFALSVFIAGGLWTIITQH
* . . : * :. :
Mb2347c|M.bovis_AF2122/97 -AYSADHLKDFVPFG-------------VAGIGSAAGTIFFSYIGLDAVS
Rv2320c|M.tuberculosis_H37Rv -AYSADHLKDFVPFG-------------VAGIGSAAGTIFFSYIGLDAVS
MAV_2087|M.avium_104 -AFDMHHLDDFAPFG-------------VAGVGTAAGTIFFSYIGLDAVS
MAB_3842|M.abscessus_ATCC_1997 -AFHAGNFSDFAPFG-------------VSGIGAAAGTIFFTYVGLDTVS
MSMEG_1412|M.smegmatis_MC2_155 -AFTTDHFAGFWDKG-------------FAGITAAAGSIFFTFIGLDAVS
Mflv_0187|M.gilvum_PYR-GCK -DVDASRLALGPDVD-------------AYGVLQAAGLLFFAFAGYARIA
Mvan_0718|M.vanbaalenii_PYR-1 -GADTSRLALGDDVT-------------VYGVLQAAGLLFFAFAGYARIA
MMAR_2579|M.marinum_M -FVDGSRVSPAHYPS-------------FGVIVYAGALIFLGYEGFELIA
MUL_3182|M.ulcerans_Agy99 -FVDGSRFSPAHYPS-------------FGVIVYAGALIFLGYEGFELIA
TH_4382|M.thermoresistible__bu ADVDFTRVVAFETTTDKSV---------FLAVSAATSLAFFAMVGFEDSV
MLBr_01974|M.leprae_Br4923 VNNYVTSRSAYQPTTYSLLGVTEIGKSTAASMTLATIVALYAFTGFESIA
: * : *
Mb2347c|M.bovis_AF2122/97 TAGDEVKDPQKTMPRALIAALVVVTGVYVLVALAALGTQP----WQDF--
Rv2320c|M.tuberculosis_H37Rv TAGDEVKDPQKTMPRALIAALVVVTGVYVLVALAALGTQP----WQDF--
MAV_2087|M.avium_104 TAGDEVTNPQKTMPRALIAALLTVTGVYVFVALAALGTQP----WQDF--
MAB_3842|M.abscessus_ATCC_1997 TAGEEVKDPQRTMPRALIAALLIVTAFYLVVALAALGAQP----WKEF--
MSMEG_1412|M.smegmatis_MC2_155 TAGDEVKNPQKTMPRAILGALVVVASVYILVAFAGLGTQS----ADEFGS
Mflv_0187|M.gilvum_PYR-GCK TLGEEVRDPARTIPRAIGLALVIALLTYAVVAVAVLAQLG----STGL--
Mvan_0718|M.vanbaalenii_PYR-1 TLGEEVRDPARTIPRAVALALVIALMVYAVVAVAVVSELG----VAGL--
MMAR_2579|M.marinum_M NAAEDARNPRRSLPLAYLISIGVVIVLYVLVAFVAVGNLD----VAQID-
MUL_3182|M.ulcerans_Agy99 NAAEDARNPRRSLLLAYLISIGVVIVLYVLVAFVAVGNLD----VAQID-
TH_4382|M.thermoresistible__bu NMAEETRDPVVIFPRALLTGLGIAGAVYVVVAIVAVALVP----VGTL--
MLBr_01974|M.leprae_Br4923 NAAEEMNTPDRTLPKAIPLTILTVGVIYILALVVAMLLGSDKIV------
. .:: * : * : . * .. .. :
Mb2347c|M.bovis_AF2122/97 AEQETAGLAIILDNVTHG--EWASTILAAGAVVSIFTVTLVTMYGQTRIL
Rv2320c|M.tuberculosis_H37Rv AEQETAGLAIILDNVTHG--EWASTILAAGAVVSIFTVTLVTMYGQTRIL
MAV_2087|M.avium_104 GGQQEAGLATILDHVTHG--SWASTILAAGAVISIFSVTLVTMYGITRIL
MAB_3842|M.abscessus_ATCC_1997 EGQ-SAGLALILDKVTGS--TSASTFLAAGAVISIFSITLVSMYGQTRIL
MSMEG_1412|M.smegmatis_MC2_155 EEQSEAGLAVILTNILHGQ-TWASTILSFGAVISIFSVTLVVMYGQTRIL
Mflv_0187|M.gilvum_PYR-GCK ---ATADAPLADAVRAAGL-PALAPVVAVGAALAALGALLALLLGVSRTT
Mvan_0718|M.vanbaalenii_PYR-1 ---ASATAPLSDAVRAAGF-PGLTPVVNVGAAIAALGALLALLLGVSRTT
MMAR_2579|M.marinum_M ---HDRDYALAAAARPFLG-SAGFELIGIAAVISTASAINATLYGTGKFT
MUL_3182|M.ulcerans_Agy99 ---HDRDYAPAVAARPFLG-SAGFELIGIAAVISTASAINATLYGTGKFT
TH_4382|M.thermoresistible__bu ---QASDVPLVEVVKAGAPGLPIEELLPWISMFAVSNTALINMLMASRLI
MLBr_01974|M.leprae_Br4923 ----ATNHTVKLAAAVGNN--TFRTIIVVGALVSMFGINVAASFGAPRLW
. .: : .: :
Mb2347c|M.bovis_AF2122/97 FAMGRDGLLPARFAKVNPRTMTPVHNTVIVAIFAS-------TLAAFIPL
Rv2320c|M.tuberculosis_H37Rv FAMGRDGLLPARFAKVNPRTMTPVHNTVIVAIFAS-------TLAAFIPL
MAV_2087|M.avium_104 FAMGRDGLLPPRFARVNPRTMTPVNNTVIVAVAAA-------TLAAFIPL
MAB_3842|M.abscessus_ATCC_1997 FAIGRDGLLPSVFAQVNPRTLTPVNNTIIVAVVVG-------FMAAFVPL
MSMEG_1412|M.smegmatis_MC2_155 FAMGRDGLLPSMFARVNSHTMTPINNTIVVALVTG-------TLAGFVPL
Mflv_0187|M.gilvum_PYR-GCK LAMARDRHLPHPLAHVHPGHGTPQRAEVAVGVVVA-------VVAAVVDV
Mvan_0718|M.vanbaalenii_PYR-1 LAMARDRYLPAGLAAVHPKHGTPHHAEVAVGLVVA-------VVAAFVDL
MMAR_2579|M.marinum_M YLMARNGELPAALG--KPVWDRPIGGLLATTAGTL-------VVVNAVDI
MUL_3182|M.ulcerans_Agy99 YLMARNGELPVALG--KPVWDRPIGGLLATTAGTL-------VVVNAVDI
TH_4382|M.thermoresistible__bu YGMARQRVLPPVLGSVHPRRRTPWVAIIFTTLIAFGLIFYVTAFADSTAI
MLBr_01974|M.leprae_Br4923 TALSDGRILPTRLSS-KNRFGVPIVAFGITAFLTLAFP-----LSLRFDS
:. ** :. : * . . .
Mb2347c|M.bovis_AF2122/97 DSLADMVSIGTLTAFSVVAVGVIVLRVREPDLPRGFK--VPGYPVTPVLS
Rv2320c|M.tuberculosis_H37Rv DSLADMVSIGTLTAFSVVAVGVIVLRVREPDLPRGFK--VPGYPVTPVLS
MAV_2087|M.avium_104 QNLADMVSIGTLTAFVVVSVGVIVLRVREPDLPRGFR--VPGYPVTPVLS
MAB_3842|M.abscessus_ATCC_1997 DSLANMVSIGTLTAFIVVSIGVIILRVREPELPRAFR--VPGYPVTPVLS
MSMEG_1412|M.smegmatis_MC2_155 DYLWDLVSIGTLVAFIVVSAGVVLLRVREPDLPRSFK--VPGYPVTPVLS
Mflv_0187|M.gilvum_PYR-GCK RSAIGFSSFGVLLYYAVANASAWTLTA------------TPRARLVPAVG
Mvan_0718|M.vanbaalenii_PYR-1 RGAIGFSSFGVLLYYAIANASAWTLG----------------ARLIPAIG
MMAR_2579|M.marinum_M EGISLMGSAGFLLIFAAVNLAVLRLRITRLTRVLAVTGAVACVASFAAMT
MUL_3182|M.ulcerans_Agy99 EGISLMGSAGFLLIFAAVNLAVLRLRITRLTRVLAVTGAVACVASFAAMT
TH_4382|M.thermoresistible__bu AVLGGTTSLLLLAVFAMVNVAVLVLRRDESRDPVVARRHFRTPTFLPVVG
MLBr_01974|M.leprae_Br4923 LNLTGLAVIARFIQFIIVPIALFALARSRTTNSVYVKRNVFTDKVLPITA
: : . . * .
Mb2347c|M.bovis_AF2122/97 VLACGYILASLHWYTWLAFS---GWVAVAVIFYLMWGRHHSALNEEV---
Rv2320c|M.tuberculosis_H37Rv VLACGYILASLHWYTWLAFS---GWVAVAVIFYLMWGRHHSALNEEV---
MAV_2087|M.avium_104 IMACGYILASLHWYTWIAFS---GWVLLALIFYFVWGRHHSALNDAA---
MAB_3842|M.abscessus_ATCC_1997 VIACGYILFSLPWITWIAFG---AWVAIVLVFYLVWGRHHSALNDLP---
MSMEG_1412|M.smegmatis_MC2_155 IIACLFVLYGLPAVTWLWFS---VWVGAVLLFYLLWGRRHSALNDGGDGY
Mflv_0187|M.gilvum_PYR-GCK LIGCVVLAFTLPPVSVLAGA---AVVLVGMLAYTTGGALRRGV-------
Mvan_0718|M.vanbaalenii_PYR-1 LVGCLVLAFTLPLTSVLAGA---AVVLVGMIAYTIGGTR-----------
MMAR_2579|M.marinum_M VYAAATTPAHLWVLGGFLVG---AIVVEGLVRLRGRHVSHPPMRPEH---
MUL_3182|M.ulcerans_Agy99 VYVAATTPAHLCVLGGFLVG---AIVVEGLVRLRGRHVSHPPMRPEH---
TH_4382|M.thermoresistible__bu FVASLYLVTPLSGRPAQQYL---LSVVLIVIGVLLFGVTMAINRQLGIPT
MLBr_01974|M.leprae_Br4923 VVVSAGLMVSFDYRSIFLTRGGPNYFSISLIAITFIGIPAVAYLHYYRTS
. . : . ::
Mb2347c|M.bovis_AF2122/97 -P------------------
Rv2320c|M.tuberculosis_H37Rv -P------------------
MAV_2087|M.avium_104 -VDPSGQER-----------
MAB_3842|M.abscessus_ATCC_1997 -SDPAELSEKEPV-------
MSMEG_1412|M.smegmatis_MC2_155 IPGAAAGEDDVMTGHPEDRA
Mflv_0187|M.gilvum_PYR-GCK --------------------
Mvan_0718|M.vanbaalenii_PYR-1 --------------------
MMAR_2579|M.marinum_M --------------------
MUL_3182|M.ulcerans_Agy99 --------------------
TH_4382|M.thermoresistible__bu RAVGDPAKMVLPPD------
MLBr_01974|M.leprae_Br4923 GIK-----------------