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M. marinum M MMAR_4876 (ctpV)

annotation: metal cation transporter p-type ATPase, CtpV
coordinates: 5929541 - 5931943
length: 800

MLATELACAADATVTVVSAAAGRMRVHANGLAIDATRAAAIEESVGRVGGVRAVRAYPRTASVVIWYSPA
QCDTAAIVSAIAEAEHAGDASVPAPAARAAGIADSGIVGRVIGGLARALLGMRTADNDDDPPPEIARLRA
ALDRIGYSPEQDTATQLSPSEQARSGIRFWSRRAWLAWPLGLLASGLTMFFGAYAWAGWLAFAATIPVQF
IAGWPFLVGAVQQARARSANMNTLISLGTLTAFIYSTYQLFAGGPLFFDTAALIIAFVVLGRYFEATAHG
KTREAISKLLEMGAKEARLIVDGEEHLVPVDRVQVGDLVRVRPGEKIPVDGEVIDGRAAVDESMLTGESV
PVEKGVGDRVAGATVNTDGLLTVRATAVGADTALAQIVRLVEEAQGGKAPVQRLADRVSAVFVPVVVGIA
AATFAGWTLLAANPVAGMTAAVSVLIIACPCALGLATPTAIIVGTGRGADMGILVKGGEVLEASKKIDTV
VFDKTGTLTRAQMELTDVIAGKRRQPDAVLRIAAAVEAGSEHPIGAAIVAGARERELEIPPATEFTNLAG
HGVRGEVGGKSVLVGRRKLVDEQHLRLPEQLAAAAADLEERGRTAVFVGQDGQVVGVLAVADTVKDDAAD
VVRQLHAMGLQVALITGDNARTAAAIAAQVGIDRVLAEVLPADKVNEVRRLQDEGRIVAMVGDGVNDAPA
LVQADLGIAIGTGTDVAIEASDITLMSGRLDGVVSAIELSRRTLRTIYQNLGWAFGYNTAAIPLAALGVL
NPVVAGAAMGLSSVSVVTNSLRLRRFGRDV
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_4876ctpV-100% (800)metal cation transporter p-type ATPase, CtpV
M. marinum MMMAR_1431zntA0.078.18% (802) cation transport ATPase, ZntA
M. marinum MMMAR_2536-0.076.68% (776) metal cation transporter p-type ATPase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0994ctpV0.078.12% (777) metal cation transporter P-type ATPase CtpV
M. gilvum PYR-GCKMflv_2244-1e-17850.58% (684) heavy metal translocating P-type ATPase
M. tuberculosis H37RvRv0969ctpV0.078.25% (777) metal cation transporter P-type ATPase CtpV
M. leprae Br4923MLBr_01987ctpA1e-15048.05% (616) putative cation-transporting ATPase
M. abscessus ATCC 19977MAB_3984c-1e-15649.29% (635) putative metal transporter ATPase
M. avium 104MAV_5246-1e-16945.04% (806) copper-translocating P-type ATPase
M. smegmatis MC2 155MSMEG_5014-0.054.93% (619) copper-translocating P-type ATPase
M. thermoresistible (build 8)TH_4361-0.047.83% (784) PUTATIVE heavy metal translocating P-type ATPase
M. ulcerans Agy99MUL_0423ctpV0.097.68% (777) metal cation transporter p-type ATPase, CtpV
M. vanbaalenii PYR-1Mvan_4449-1e-18050.43% (696) heavy metal translocating P-type ATPase

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_4876|M.marinum_M               MLATELACAADATVTVVSAAAGRMRVHANGLAIDATRAAAIEESVGRVGG
MUL_0423|M.ulcerans_Agy99           -----------------------MRVHANGFAIDATRAAAIEESVGRVGG
Mb0994|M.bovis_AF2122/97            -----------------------MRVCVTGFNVDAVRAVAIEETVSQVTG
Rv0969|M.tuberculosis_H37Rv         -----------------------MRVCVTGFNVDAVRAVAIEETVSQVTG
Mflv_2244|M.gilvum_PYR-GCK          ----------------------------------------MNTLELSIGG
Mvan_4449|M.vanbaalenii_PYR-1       ----------------------------------------MNTIELSIGG
MSMEG_5014|M.smegmatis_MC2_155      ------------------------------------MTTATGHVELQIGG
TH_4361|M.thermoresistible__bu      -----------------------------------MNTGGMNTVTLTVGG
MAV_5246|M.avium_104                ---------------------MSTPPRHIDEGTFPDHTASTARIELEITG
MAB_3984c|M.abscessus_ATCC_199      ---------------------------------METTNTGMETTDLRLHG
MLBr_01987|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MMAR_4876|M.marinum_M               VRAVRAYPRTASVVIWYSPAQCDTAAIVSAIAEAEHAGDASVPAPAARAA
MUL_0423|M.ulcerans_Agy99           VRAVRAYPRTASVVIWYSPAHCDTAAIVSAIAEAEHAGDASAPAPAARVA
Mb0994|M.bovis_AF2122/97            VHAVHAYPRTASVVIWYSPELGDTAAVLSAITKAQHVPAELVPARAPHSA
Rv0969|M.tuberculosis_H37Rv         VHAVHAYPRTASVVIWYSPELGDTAAVLSAITKAQHVPAELVPARAPHSA
Mflv_2244|M.gilvum_PYR-GCK          MTCASCAARVEKKLN----KLDGVTATVNYATEKARVEFGDNVSTDQLVS
Mvan_4449|M.vanbaalenii_PYR-1       MTCASCAARVEKKLN----KLDGVTATVNFATEKARVAFGDEVSPGQLVS
MSMEG_5014|M.smegmatis_MC2_155      MTCASCAARIERKLN----KLDGVTASVNYATEKASVEVAGEVSPETLIE
TH_4361|M.thermoresistible__bu      MTCASCAARVEKRLN----RIDGVVATVNFATEQATVRYPDHVDPADLIA
MAV_5246|M.avium_104                MTCASCAARIEKKLN----KLDGVTATVNYATEKAAVSAPASYDPQTLIT
MAB_3984c|M.abscessus_ATCC_199      MTCASCASRVEKGLN----KITGVNARVNLALESARVEHDGSVTGEDLVK
MLBr_01987|M.leprae_Br4923          MRAPNGWNNLPNKLS-------DFSTLVNSATRVAAINLSEVTQTAEVCE
                                    : .     .    :        .  : :.   .                 

MMAR_4876|M.marinum_M               GIADSGIVGRVIGGLARALLGMRTADNDDDPPPEIARLRAALDRIGYSPE
MUL_0423|M.ulcerans_Agy99           GIADGGVVGRVIGGLARALLGMRTDDNDDDPPPEIARLRAALDRIGYSPE
Mb0994|M.bovis_AF2122/97            GVRGVGVVRKITGGIRRMLS----------RPPGVDKPLKASRCGGRPRG
Rv0969|M.tuberculosis_H37Rv         GVRGVGVVRKITGGIRRMLS----------RPPGVDKPLKASRCGGRPRG
Mflv_2244|M.gilvum_PYR-GCK          AVESAGYQAALPEP--------------------------------PNPP
Mvan_4449|M.vanbaalenii_PYR-1       AVESAGYQAELPER--------------------------------PDEP
MSMEG_5014|M.smegmatis_MC2_155      VVETAGYTAHLPAP--------------------------------PQPE
TH_4361|M.thermoresistible__bu      AIEATGYTASLPAPQRDTGGA-------------------------PAGA
MAV_5246|M.avium_104                EIENAGYAAAVATP---------------------------------SPP
MAB_3984c|M.abscessus_ATCC_199      AVESVGYTAQVVGGSHQDAHAG------------------------DHDG
MLBr_01987|M.leprae_Br4923          AVRRAALCTDGGEALQR---------------------------------
                                     :   .                                            

MMAR_4876|M.marinum_M               QDTATQLSPSEQARSGIRFWSRRAWLAWPLGLL-ASGLTMFFGAYAWAGW
MUL_0423|M.ulcerans_Agy99           QDTATQLSPSEQARSGIRFWSRRAWLAWPLGLL-ASGLTMFFGAYPWAGW
Mb0994|M.bovis_AF2122/97            PVRGSASWPGEQNRRERRTWLPRVWLALPLGLL-ALGSSMFFGAYPWAGW
Rv0969|M.tuberculosis_H37Rv         PVRGSASWPGEQNRRERRTWLPRVWLALPLGLL-ALGSSMFFGAYPWAGW
Mflv_2244|M.gilvum_PYR-GCK          D-----VEPADPTAALRRRLIICVALSVPVIAM-AMAPPLQFTYW---QW
Mvan_4449|M.vanbaalenii_PYR-1       A-----EPTDDPTAALKRRLLICVALSVPVIAM-AMVPVLQFTYW---QW
MSMEG_5014|M.smegmatis_MC2_155      TGGTEQDPEDRATDALRTRLLVSAVLTVPVIAM-AMVPALQFTNW---QW
TH_4361|M.thermoresistible__bu      ATGAAGDDHDAEAERWRRRLTISAALSIPVVVL-SMIPALQFTHW---QW
MAV_5246|M.avium_104                R-------DDPELASLRRRLVTAIALAGPVIAV-AMIPALQFQHW---HW
MAB_3984c|M.abscessus_ATCC_199      HDPHDHMNHDVPDDQLKSRLIGSLILAIPVVVI-SMAMPLHFSGW---EI
MLBr_01987|M.leprae_Br4923          -----RQADADNARYLLIRLAVAAALFVPLAHLSVMFAVLPSTHFPGWEW
                                                             *  *:  :      :    :     

MMAR_4876|M.marinum_M               LAFAATIPVQFIAGWPFLVGAVQQARARSANMNTLISLGTLTAFIYSTYQ
MUL_0423|M.ulcerans_Agy99           LAFAATIPVQFIAGWPFLVGAVQQARARSANMNTLISLGTLTAFIYSTYQ
Mb0994|M.bovis_AF2122/97            LAFAATLPVQFVAGWPILRGAVQQARALTSNMDTLIALGTLTAFVYSTYQ
Rv0969|M.tuberculosis_H37Rv         LAFAATLPVQFVAGWPILRGAVQQARALTSNMDTLIALGTLTAFVYSTYQ
Mflv_2244|M.gilvum_PYR-GCK          LSLTLAAPVVVWGAWPFHRATWANLRHGTATMDTLISVGTLAAFGWSIYA
Mvan_4449|M.vanbaalenii_PYR-1       LSLTLAAPVVVWGAWPFHQAAWTNLRHGTATMDTLISIGTLAALGWSIYA
MSMEG_5014|M.smegmatis_MC2_155      LSLTLAAPVVVWGALPFHRAAWLNLRHGTATMDTLISMGTLAAFGWSLYA
TH_4361|M.thermoresistible__bu      LALTLTSPVVVWGAWPFHRAAVANLRHGTATMDTLISLGVTAAYLWSLWA
MAV_5246|M.avium_104                AALALTAPVVGWCGRPFHAAAWANLKHGVTTMDTLISIGTLAAFLWSLYA
MAB_3984c|M.abscessus_ATCC_199      LVAALTTPILLWGGYPFHRAALVNARHGASTMDTLVSLGTIAAYLWSLWV
MLBr_01987|M.leprae_Br4923          MLTALAIPVVTWAAWPFHRVAIHNARYHGASMETLISTGITAATIWSLYT
                                       : : *:    . *:   :  : :   :.*:**:: *  :*  :* : 

MMAR_4876|M.marinum_M               LFAGGP---------------------------LFFDTAALIIAFVVLGR
MUL_0423|M.ulcerans_Agy99           LFAGGP---------------------------LFFDTAALIIAFVVLGR
Mb0994|M.bovis_AF2122/97            LFAGGP---------------------------LFFDTSALIIAFVVLGR
Rv0969|M.tuberculosis_H37Rv         LFAGGP---------------------------LFFDTSALIIAFVVLGR
Mflv_2244|M.gilvum_PYR-GCK          LFWGTAGVPGMTHPFELTI------ARTDGSGNIYLEAAAGVTTFILAGR
Mvan_4449|M.vanbaalenii_PYR-1       LFWGTAGIPGMTHPFELTI------ARTDGTSNIYLEAAAGVTTFILAGR
MSMEG_5014|M.smegmatis_MC2_155      LFWGTAGVPGMTHPFSLVG------SRTDGAGNIYLEVAAGVTTFILAGR
TH_4361|M.thermoresistible__bu      LFFTAAGMPGMTMTFTLLP------ADT-GEPHIYLEVAAAVTTFIIAGR
MAV_5246|M.avium_104                LVLGAADRPGMRHDFELTVGHGAHVSHVAAPCHVYFEVAAGVTLFVLAGR
MAB_3984c|M.abscessus_ATCC_199      LFANAG--------------------HTHGDVHVYFEVVAAVTVFLLAGR
MLBr_01987|M.leprae_Br4923          VFGHHQSTEHRGVWRALLG-----------SDAIYFEVAAGITVFVLAGK
                                    :.                               ::::. * :  *:: *:

MMAR_4876|M.marinum_M               YFEATAHGKTREAISKLLEMGAKEARLIV-DGEEHLVPVDRVQVGDLVRV
MUL_0423|M.ulcerans_Agy99           YFEATAHGKTREAISKLLDMGAKETRLIV-DGEEHLVPVDRVQVGDLVRV
Mb0994|M.bovis_AF2122/97            HLEARATGKASEAISKLLELGAKEATLLV-DGQELLVPVDQVQVGDLVRV
Rv0969|M.tuberculosis_H37Rv         HLEARATGKASEAISKLLELGAKEATLLV-DGQELLVPVDQVQVGDLVRV
Mflv_2244|M.gilvum_PYR-GCK          YFEARAKRRAGAALRALLELGVRDVTVRR-GAAEHRIPIDQLRVDDEFVV
Mvan_4449|M.vanbaalenii_PYR-1       YFEARAKRRAGAALRALLELGAREVTVRR-GGAEQRIPIEQLVIGDEFVV
MSMEG_5014|M.smegmatis_MC2_155      YFEAKSKRRASAALRALMELGAKDVAILR-NGAEQRIPIDQLGVGDEFVV
TH_4361|M.thermoresistible__bu      YFEARAKRQSGAALRALLDMGANDVAVLR-DGAEKRVPIGELHVGDVFVV
MAV_5246|M.avium_104                YFERRSKRTAGAALRALLALGAKDVAVLR-AGAETRIPIERLAVGDEFVV
MAB_3984c|M.abscessus_ATCC_199      FAESRAKRSAGSALRALLSLGAKDVAVLR-GGHETRIPVDQLAVGDEFVV
MLBr_01987|M.leprae_Br4923          YYTARAKSHASIALLALAALSAKDAAVLQPDGSEMVIPANELNEQQRFVV
                                    .    :   :  *:  *  :...:. :    . *  :*  .:   : . *

MMAR_4876|M.marinum_M               RPGEKIPVDGEVIDGRAAVDESMLTGESVPVEKGVGDRVAGATVNTDGLL
MUL_0423|M.ulcerans_Agy99           RPGEKIPVDGEVIDGRAAVDESMLTGESVPVEKGVGDWVAGATVNTDGLL
Mb0994|M.bovis_AF2122/97            RPGEKIPVDGEVTDGRAAVDESMLTGESVPVEKTAGDRVAGATVNLDGLL
Rv0969|M.tuberculosis_H37Rv         RPGEKIPVDGEVTDGRAAVDESMLTGESVPVEKTAGDRVAGATVNLDGLL
Mflv_2244|M.gilvum_PYR-GCK          RPGEKVAADGIIVEGASAVDASMLTGESVPLEVKPGDRVVGATVNVDGRL
Mvan_4449|M.vanbaalenii_PYR-1       RPGEKIAADGTVVEGASAVDASMLTGESVPEEVQPGDQVVGATVNVDGRL
MSMEG_5014|M.smegmatis_MC2_155      RPGEKIATDGVVVDGSSAVDASMLTGESVPVEVGPGDQVVGATVNVGGRL
TH_4361|M.thermoresistible__bu      RPGEKIATDGEVVAGNSAVDASMLTGESVPVEVGPGDQVVGATVNVGGHL
MAV_5246|M.avium_104                RPGERIATDGIVVAGSSAVDAAMLTGESVPVEVGVGDGVTGGTVNAGGRL
MAB_3984c|M.abscessus_ATCC_199      RPGERVATDGEVIEGHSALDTSTMTGESVPMEVTVGGPVLGGYVNTHGRI
MLBr_01987|M.leprae_Br4923          RPGQTIAADGLVIDGSATVSMSPITGEAKPVRVNPGAQVIGGTVVLNGRL
                                    ***: :..** :  * :::. : :***: * .   *  * *. *   * :

MMAR_4876|M.marinum_M               TVRATAVGADTALAQIVRLVEEAQGGKAPVQRLADRVSAVFVPVVVGIAA
MUL_0423|M.ulcerans_Agy99           TVRATAVGADTALAQIVRLVEEAQGGKAPVQRLADRVSAVFVPVVVRIAA
Mb0994|M.bovis_AF2122/97            TVRATAVGADTALAQIVRLVEQAQGDKAPVQRLADRVSAVFVPAVIGVAV
Rv0969|M.tuberculosis_H37Rv         TVRATAVGADTALAQIVRLVEQAQGDKAPVQRLADRVSAVFVPAVIGVAV
Mflv_2244|M.gilvum_PYR-GCK          VVRAERVGADTQLAQMARLVEDAQNGKAQAQRLADRISGVFVPVVLGLAV
Mvan_4449|M.vanbaalenii_PYR-1       VVRADRVGSDTQLAQMARMVEDAQNGKAQAQRLADRISGVFVPIVIALSV
MSMEG_5014|M.smegmatis_MC2_155      VVRANRIGSDTQLAQMARLVEDAQSGKAQAQRLADRVSAVFVPIVIALAV
TH_4361|M.thermoresistible__bu      QVRATRVGADTQLAQMARLVTEAQSGKAEVQRLADRVSAVFVPIVIALSA
MAV_5246|M.avium_104                VVRATGIGDDTQLARMAQLVERAQSGKADAQRLADRVSGVFVPVVLLLAV
MAB_3984c|M.abscessus_ATCC_199      VVRANKVGADTQLARMARLVSDAQTGKAQVQRLADRVSSVFVPVVLAISA
MLBr_01987|M.leprae_Br4923          IVEAAAVGDETQLAGMVRLVEQAQQQNANAQRLADRIASVFVPCVFAVAA
                                     *.*  :* :* ** :.::*  **  :* .******::.**** *. ::.

MMAR_4876|M.marinum_M               ATFA-GWTLLAANPVAGMTAAVSVLIIACPCALGLATPTAIIVGTGRGAD
MUL_0423|M.ulcerans_Agy99           ATFA-GWTLLAANPVAGMTAAVSVLIIACPYALGLATPTAIIVGTGRGAD
Mb0994|M.bovis_AF2122/97            ATFA-GWTLIAANPVAGMTAAVAVLIIACPCALGLATPTAIMVGTGRGAE
Rv0969|M.tuberculosis_H37Rv         ATFA-GWTLIAANPVAGMTAAVAVLIIACPCALGLATPTAIMVGTGRGAE
Mflv_2244|M.gilvum_PYR-GCK          ATLG-FWIGSGYPVAAAFTAAVAVLIIACPCALGLATPMALMVGTGRGAQ
Mvan_4449|M.vanbaalenii_PYR-1       ATLG-FWIGSGFPVAAAFTAAVAVLIIACPCALGLATPTALMVGTGRGAQ
MSMEG_5014|M.smegmatis_MC2_155      ATLG-FWLGTGGSVAAAFTAAVAVLIIACPCALGLATPTALLVGTGRGAQ
TH_4361|M.thermoresistible__bu      LTLAGWLLLTDAPVSAAFTAAVAVLIIACPCALGLATPTALLVGTGRGAQ
MAV_5246|M.avium_104                ATLA-GWLAAGGTLATALTAAVAVLIIACPCALGLATPTALLVGTGRAAQ
MAB_3984c|M.abscessus_ATCC_199      LTFV-AWAALGNSLASAFTAAVAVLIIACPCALGLATPTAILVGTGRGAQ
MLBr_01987|M.leprae_Br4923          LTAV-GWLIAGSGPDRVFSAAIAVLVIACPCALGLATPTAMMVASGRGAQ
                                     *               ::**::**:**** ******* *::*.:**.*:

MMAR_4876|M.marinum_M               MGILVKGGEVLEASKKIDTVVFDKTGTLTRAQMELTDVIAGKRR---QPD
MUL_0423|M.ulcerans_Agy99           MGILVKGGEVLEASKKIDTVVFDKTGTLTRAQMELTDVIAGKRR---QPD
Mb0994|M.bovis_AF2122/97            LGILVKGGEVLEASKKIDTVVFDKTGTLTRARMRVTDVIAGQRR---QPN
Rv0969|M.tuberculosis_H37Rv         LGILVKGGEVLEASKKIDTVVFDKTGTLTRARMRVTDVIAGQRR---QPD
Mflv_2244|M.gilvum_PYR-GCK          LGILIKGPEVLESTRRVDTVIVDKTGTVTTGDMTLVDVFAADGE---QPD
Mvan_4449|M.vanbaalenii_PYR-1       LGILIKGPEVLEDTRRVDTVILDKTGTVTTGSMTLVDVFAAEGE---QPD
MSMEG_5014|M.smegmatis_MC2_155      LGILIKGPEVLESTRRVDTIVLDKTGTITTGSMTLLDVVVADGE---DRD
TH_4361|M.thermoresistible__bu      LGILIKGPQVLESTRRIDTVVLDKTGTVTTGQMSVTSVHVADGL---SET
MAV_5246|M.avium_104                LGVLIKGPEVLETTRAVDTVVLDKTGTVTTGAMTVLDVVAADGT---DRA
MAB_3984c|M.abscessus_ATCC_199      LGVLIKGPEVLENVKDIDTVVLDKTGTVTTGVMSVVEVRRSIGSGVADAD
MLBr_01987|M.leprae_Br4923          LGILLKGHESFEATRAVDTVVFDKTGTLTTGQLKVSAVTAAPGW---QAN
                                    :*:*:** : :*  : :**::.*****:* . : :  *  .      .  

MMAR_4876|M.marinum_M               AVLRIAAAVEAGSEHPIGAAIVAGARERELEIPPATEFTNLAGHGVRGEV
MUL_0423|M.ulcerans_Agy99           VVLRIAAAVESGSEHPIGAAIVAGARERELEVPPATEFTNLAGHGVRGEV
Mb0994|M.bovis_AF2122/97            QVLRLAAAVESGSEHPIGAAIVAAAHERGLAIPAANAFTAVAGHGVRAQV
Rv0969|M.tuberculosis_H37Rv         QVLRLAAAVESGSEHPIGAAIVAAAHERGLAIPAANAFTAVAGHGVRAQV
Mflv_2244|M.gilvum_PYR-GCK          EVLRMAGAVESPSEHPIAAAIAGGARDKLGDLPAVDGFANLRGLGVEGDV
Mvan_4449|M.vanbaalenii_PYR-1       EVLRVAGAVESSSEHPIARAIAAGAQEKFGELPAVTAFTNLRGLGVSGQV
MSMEG_5014|M.smegmatis_MC2_155      DVLRVAAAVEDASEHPIARAIAAGARERTGELPAVEGFANIEGLGVQGTV
TH_4361|M.thermoresistible__bu      ELLRLAGAVEHASEHPIARAVATHAAQTVPPLPEVSDFENHGGNGVSGRV
MAV_5246|M.avium_104                TLLRYAGALEAASEHPIAHAIARDAKAELGPLPTPTGFRAVGGGGVHGRV
MAB_3984c|M.abscessus_ATCC_199      EILRIAASVESASEHPVARAIVAAAASARLTLSPVTNFRNEPGVGVSGVV
MLBr_01987|M.leprae_Br4923          EVLQMAATVESASEHAVALAIAASTTHR----EPVANFRAVPGHGVSGTV
                                     :*: *.::*  ***.:. *:.  :            *    * ** . *

MMAR_4876|M.marinum_M               GGKSVLVGRRKLVDEQHLRLPEQLAAAAADLEERGRTAVFVGQDGQVVGV
MUL_0423|M.ulcerans_Agy99           GGKSVLVGRRKLVDEQHLRLPEQLAAAAADLEERGRTAVYVGQDGQVVGV
Mb0994|M.bovis_AF2122/97            NGGPVVVGRRKLVDEQHLVLPDHLAAAAVEQEERGRTAVFVGQDGQVVGV
Rv0969|M.tuberculosis_H37Rv         NGGPVVVGRRKLVDEQHLVLPDHLAAAAVEQEERGRTAVFVGQDGQVVGV
Mflv_2244|M.gilvum_PYR-GCK          EGRRLTLGRLRLLSDRSFEIPDDLASAVARAEAGGSTAVTVGWDGRARGV
Mvan_4449|M.vanbaalenii_PYR-1       DGRAVLLGRLRLLADRSHEIPSELEVAVARAESDGRTAVVVGWDGQARGV
MSMEG_5014|M.smegmatis_MC2_155      EGRAVVVGRPRLFGDPEKSLPRKLADAMEAAQAQGRTAVVVGWDGTARGV
TH_4361|M.thermoresistible__bu      DGHDVRVGRLAWLG---LSAGDRLRNAAAQAEAAGHTPVWVAVDGRIAGV
MAV_5246|M.avium_104                DGHAVAIGRPSWLAERGLRPDAALAAAAARAEHDGKTVVAVGWDGRARGI
MAB_3984c|M.abscessus_ATCC_199      DGQEVSI----------------------EAIEGQNTTAAVSWGGLRRGE
MLBr_01987|M.leprae_Br4923          AERAVRVGKPSWIASR--CNSTTLVTARRNAELRGETAVFVEIDGEQCGV
                                        : :                             * . *  .*   * 

MMAR_4876|M.marinum_M               LAVADTVKDDAADVVRQLHAMGLQVALITGDNARTAAAIAAQVGID--RV
MUL_0423|M.ulcerans_Agy99           LAVADTVKDDAADVVSQLHAMGLQVALITGDNARTAAAIAAQVGID--RV
Mb0994|M.bovis_AF2122/97            LAVADTVKDDAADVVGRLHAMGLQVAMITGDNARTAAAIAKQVGIE--KV
Rv0969|M.tuberculosis_H37Rv         LAVADTVKDDAADVVGRLHAMGLQVAMITGDNARTAAAIAKQVGIE--KV
Mflv_2244|M.gilvum_PYR-GCK          LMVADAVKPTSAEAISLLKRAGLTPIMVTGDNEAVARTVAAQVGID--EV
Mvan_4449|M.vanbaalenii_PYR-1       LMVADAVKPTSAEAISLLKRLGLTPIMVTGDNEAVARAVAAEVGID--EV
MSMEG_5014|M.smegmatis_MC2_155      LVVADAVKATSAEAIGQLRKLGLQPIMLTGDNGAAARAIADQVGID--DV
TH_4361|M.thermoresistible__bu      IVVSDTVKDHAAEAIAELRALGATPVLLTGDNDRAARTVAAQVGID--DV
MAV_5246|M.avium_104                LALADTVKPSSAAAVRQFTRLGLTPILLTGDNHTVARRTAGELGIG--EV
MAB_3984c|M.abscessus_ATCC_199      IEVADTVKPSSRRAIDELKAMGITPVLLTGDNAEVAARVASEVGIAAGDV
MLBr_01987|M.leprae_Br4923          IAVADAVKASAADAVAALHDRGFRTALLTGDNPASAAAVASRIGID--EV
                                    : ::*:**  :  .:  :   *    ::****   *   * .:**    *

MMAR_4876|M.marinum_M               LAEVLPADKVNEVRRLQDEGRIVAMVGDGVNDAPALVQADLGIAIGTGTD
MUL_0423|M.ulcerans_Agy99           LAEVLPADKVNEVRRLQDEGRIVAMVGDGVNDAPALVQADLGIAIGTGTD
Mb0994|M.bovis_AF2122/97            LAEVLPQDKVAEVRRLQDQGRVVAMVGDGVNDAPALVQADLGIAIGTGTD
Rv0969|M.tuberculosis_H37Rv         LAEVLPQDKVAEVRRLQDQGRVVAMVGDGVNDAPALVQADLGIAIGTGTD
Mflv_2244|M.gilvum_PYR-GCK          VAGVLPQDKVDTVTRLQRDGRVVAMVGDGVNDAAALAQADLGMAMGSGTD
Mvan_4449|M.vanbaalenii_PYR-1       IAGVLPQDKVDTVKRLQRDGKVVAMVGDGVNDAAALAQADLGLAMGSGTD
MSMEG_5014|M.smegmatis_MC2_155      YAEVLPQDKADVIKRLQAEGRVVAMVGDGVNDAAALAQADLGLSMGTGTD
TH_4361|M.thermoresistible__bu      IAGVLPAEKVDHIKQLQDRGRVVAMIGDGVNDAAALAQADLGLAIGTGTD
MAV_5246|M.avium_104                ISGALPADKVEAVKRLQSAGRVVAMVGDGVNDAAALAAADLGLAMGTGTD
MAB_3984c|M.abscessus_ATCC_199      IAGVKPTEKADVVKRLQAEGKRVAMVGDGVNDSAALATADIGMAMGTGTD
MLBr_01987|M.leprae_Br4923          IADILPEDKVDVIEQLRDRGHVVAMVGDGINDGPALARADLGMAIGRGTD
                                     :   * :*.  : :*:  *: ***:***:**..**. **:*:::* ***

MMAR_4876|M.marinum_M               VAIEASDITLMSGRLDGVVSAIELSRRTLRTIYQNLGWAFGYNTAAIPLA
MUL_0423|M.ulcerans_Agy99           VAIEASDITLMSGRLDGVVSAIELSRRTLRTIYQNLGWAFGYNTAAIPLA
Mb0994|M.bovis_AF2122/97            VAIEASDITLMSGRLDGVVRAIELSRQTLRTIYQNLGWAFGYNTAAIPLA
Rv0969|M.tuberculosis_H37Rv         VAIEASDITLMSGRLDGVVRAIELSRQTLRTIYQNLGWAFGYNTAAIPLA
Mflv_2244|M.gilvum_PYR-GCK          VAIEASDLTLVSNDLRAVPDAIRLSRKTLSTIKSNLFWAFAYNVAALPLA
Mvan_4449|M.vanbaalenii_PYR-1       VAIEASDLTLVSNDLRAVPDAIRLSRKTLSTIKGNLFWAFAYNVAALPLA
MSMEG_5014|M.smegmatis_MC2_155      VAIEAGDLTLVRGDLRTAADAIRLSRRTLATIKGNLFWAFAYNVAALPLA
TH_4361|M.thermoresistible__bu      VAIEASDLTLVTGDLRAAPDAIRLGRATLRTIKGNLFWAFAYNVAALPLA
MAV_5246|M.avium_104                VAIEAADVTVVRGDLRAAVDAIRLSRRTLATIKTNLVWAFGYNLAAIPLA
MAB_3984c|M.abscessus_ATCC_199      AAIEASDLTLVRGDLTTVPTALRLSRKTLGTIKANLFWAFAYNTAAIPLA
MLBr_01987|M.leprae_Br4923          VAIGAADIILVRDNLDVVPITLDLAAATMRTIKFNMVWAFGYNIAAIPIA
                                    .** *.*: :: . *  .  :: *.  *: **  *: ***.** **:*:*

MMAR_4876|M.marinum_M               ALGVLNPVVAGAAMGLSSVSVVTNSLRLRRFGRDV---------------
MUL_0423|M.ulcerans_Agy99           ALGVLNPVVAGAAMGLSSVSVVTNSLRLRRFGRDV---------------
Mb0994|M.bovis_AF2122/97            ALGALNPVVAGAAMGFSSVSVVTNSLRLRRFGRDGRTA------------
Rv0969|M.tuberculosis_H37Rv         ALGALNPVVAGAAMGFSSVSVVTNSLRLRRFGRDGRTA------------
Mflv_2244|M.gilvum_PYR-GCK          AAGLLNPMIAGAAMAFSSVFVVTNSLRLRAFTPSR---------------
Mvan_4449|M.vanbaalenii_PYR-1       AAGLLNPMIAGAAMAFSSVFVVSNSLRLRAFTPSR---------------
MSMEG_5014|M.smegmatis_MC2_155      AAGLLNPMLAGAAMAFSSVFVVSNSLRLKRFR------------------
TH_4361|M.thermoresistible__bu      AAGLLNPLIAGAAMAFSSVFVVSNSLRLRRFTPSR---------------
MAV_5246|M.avium_104                ALGMLNPMLAGAAMALSSVLVVGNSLRLRSFASIIPGA------------
MAB_3984c|M.abscessus_ATCC_199      ALGLLNPMIAGAAMAMSSVFVVLNSLRLRTFR------------------
MLBr_01987|M.leprae_Br4923          AAGLLNPLVAGAAMAFSSFFVVSNSLRLRNFGAILSCGTSRHRTVKRWRC
                                    * * ***::*****.:**. ** *****: *                   

MMAR_4876|M.marinum_M               ----------------------------------
MUL_0423|M.ulcerans_Agy99           ----------------------------------
Mb0994|M.bovis_AF2122/97            ----------------------------------
Rv0969|M.tuberculosis_H37Rv         ----------------------------------
Mflv_2244|M.gilvum_PYR-GCK          ----------------------------------
Mvan_4449|M.vanbaalenii_PYR-1       ----------------------------------
MSMEG_5014|M.smegmatis_MC2_155      ----------------------------------
TH_4361|M.thermoresistible__bu      ----------------------------------
MAV_5246|M.avium_104                ----------------------------------
MAB_3984c|M.abscessus_ATCC_199      ----------------------------------
MLBr_01987|M.leprae_Br4923          PPPTRLRSTACSPVDASPLRPVAHRTGVKPPTHR