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VSLLVVAPELVTSAAADLQGIGSSVNAANAAAAISTTELTAAAADEVSAAAATLLGGFGQQYQALAGQLA TAYDQLASKLAADAAAYLGAESANANQLLSNAVNASTALVNGPFLELTGRPLIGNGADGYTNAQGIGTPG GAGGWLYGNGGSGGNSTHAGVAGGAGGNAGLIGNGGMGGAGLRGGDGGTGGLGGWLWGQAGAAGTGTPLP ANEILMRVDQYGNPVVTISVGGGPGIAVTVDTGASGLLVRPQDVNLQSLGTPTGSGAVTYGNSSYAFNTV QYQTYQTTVNFGNGIVTNPTNVAVATSATQTINGVTTSIPLSSLPLYLGIGPNNDFPLPDQVTAALPGDL NQGVLINTNLGYLQFGANPLTPVASVTGSPVTDLQIQINNGPLQPATGSFIDSGGLYGTIPSSLIPGVPV GYSVPVGTTITVYTTDGVQLYSQTVTGSTNAPLVVPSNNPFNTGNYPFLLGPIYISNSPTGGGQTIFDF
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_2272 | - | - | 100% (489) | PE-PGRS family protein |
M. marinum M | MMAR_1538 | - | e-102 | 45.22% (502) | PE family protein, PE26 |
M. marinum M | MMAR_2933 | - | 6e-91 | 39.89% (569) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2548 | PE26 | 1e-100 | 44.27% (506) | PE family protein |
M. gilvum PYR-GCK | Mflv_2178 | - | 1e-18 | 52.22% (90) | hypothetical protein Mflv_2178 |
M. tuberculosis H37Rv | Rv2519 | PE26 | 1e-100 | 44.47% (506) | PE family protein |
M. leprae Br4923 | MLBr_01183 | - | 9e-15 | 43.96% (91) | hypothetical protein MLBr_01183 |
M. abscessus ATCC 19977 | MAB_0321c | - | 6e-10 | 36.36% (132) | hypothetical protein MAB_0321c |
M. avium 104 | MAV_1346 | - | 2e-14 | 29.96% (237) | PE family protein |
M. smegmatis MC2 155 | MSMEG_0868 | - | 8e-21 | 46.03% (126) | hypothetical protein MSMEG_0868 |
M. thermoresistible (build 8) | TH_4332 | - | 9e-13 | 30.90% (233) | PUTATIVE - |
M. ulcerans Agy99 | MUL_2395 | - | 2e-64 | 41.97% (386) | PE family protein |
M. vanbaalenii PYR-1 | Mvan_0928 | - | 3e-19 | 56.32% (87) | carboxymuconolactone decarboxylase |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_2178|M.gilvum_PYR-GCK -----------MSG--TAHAPGKTRLFANVTVAVGLGGAALG--AAALLA MSMEG_0868|M.smegmatis_MC2_155 -----------MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRK MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4332|M.thermoresistible__bu -------------MPFITSGAAFVGGAAMLLAGPGGVSALEAAGSAPRTV Mb2548|M.bovis_AF2122/97 -------------MSRLIVAPDWLASAAAEVQSIGSALSAANAAAAAPTT Rv2519|M.tuberculosis_H37Rv -------------MSRLIVAPDWLASAAAEVQSIGSALSAANAAAAAPTT MUL_2395|M.ulcerans_Agy99 -------------MAQLSVAPPWLVSAAQDLQSIGSTLAAANGAAAGPTT MMAR_2272|M.marinum_M -------------MSLLVVAPELVTSAAADLQGIGSSVNAANAAAAISTT MLBr_01183|M.leprae_Br4923 ------------MPLFLNAEPQALTAAANTLEGLSAATVASNAAAAQLTT MAV_1346|M.avium_104 ------------MS-FVTTRPEALLAVASMLEGLGSSMDAQNAAAAAPTT Mvan_0928|M.vanbaalenii_PYR-1 MSGTQSAESDDDADDSEGDASADDAEDAEEFVGDSGNGGSDDDAADDSEK Mflv_2178|M.gilvum_PYR-GCK P--QASAAPEEWLP----------AGPSSECPPPT-----DGCAN----- MSMEG_0868|M.smegmatis_MC2_155 PKFPAALAPESPLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQ MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4332|M.thermoresistible__bu EYEYSLVACDSTLP------------------------------------ Mb2548|M.bovis_AF2122/97 LLVAAAEDEVSAAA------------------------------------ Rv2519|M.tuberculosis_H37Rv LLVAAAEDEVSAAA------------------------------------ MUL_2395|M.ulcerans_Agy99 VLATAAADEVSTAI------------------------------------ MMAR_2272|M.marinum_M ELTAAAADEVSAAA------------------------------------ MLBr_01183|M.leprae_Br4923 EIAPPAADDVSILL------------------------------------ MAV_1346|M.avium_104 SIAPAAADEVSALQ------------------------------------ Mvan_0928|M.vanbaalenii_PYR-1 DVDSSTDDGVGDFEGVVLDDAESEADSQLSVPQPASTESTEQSADVANDA Mflv_2178|M.gilvum_PYR-GCK -----------VAAVGGVHGAQGPANLATPQTS---GSPLFRPLFG---- MSMEG_0868|M.smegmatis_MC2_155 ATSTNTTDQPTSDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSV MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4332|M.thermoresistible__bu ---------LMCEAGDSVGGLGGASHDRSAFSASALGMASFG-------- Mb2548|M.bovis_AF2122/97 -------------------------------------------------- Rv2519|M.tuberculosis_H37Rv -------------------------------------------------- MUL_2395|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2272|M.marinum_M -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mvan_0928|M.vanbaalenii_PYR-1 DGNADPIADAGPEAVTAPVALSGASAPAIPDGPAPVEPMGPLINSLWWAV Mflv_2178|M.gilvum_PYR-GCK ---------NGADAPADC-------------------------------- MSMEG_0868|M.smegmatis_MC2_155 VTLGTTLIPNAPTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLP MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4332|M.thermoresistible__bu -------------------------------------------------- Mb2548|M.bovis_AF2122/97 -------------------------------------------------- Rv2519|M.tuberculosis_H37Rv -------------------------------------------------- MUL_2395|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2272|M.marinum_M -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mvan_0928|M.vanbaalenii_PYR-1 PKSGGRSTNDASLTLAGTG------------------------------- Mflv_2178|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 VPTVASAVLDPTQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQ MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4332|M.thermoresistible__bu -------------------------------------------------- Mb2548|M.bovis_AF2122/97 -------------------------------------------------- Rv2519|M.tuberculosis_H37Rv -------------------------------------------------- MUL_2395|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2272|M.marinum_M -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mvan_0928|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2178|M.gilvum_PYR-GCK --VGNACN-------GRDGGLIWGNGGAGAN-------GGHGGNAGLVGN MSMEG_0868|M.smegmatis_MC2_155 YLIGNGINGTADNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFGN MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------MANIISN TH_4332|M.thermoresistible__bu ---PDWNPGGAFLGLIGPGGLLIGDG-------------LNGTDAYIDEN Mb2548|M.bovis_AF2122/97 -------------------------------------------AALFANY Rv2519|M.tuberculosis_H37Rv -------------------------------------------AALFANY MUL_2395|M.ulcerans_Agy99 -------------------------------------------AALFAGH MMAR_2272|M.marinum_M -------------------------------------------ATLLGGF MLBr_01183|M.leprae_Br4923 -------------------------------------------AHFFSGH MAV_1346|M.avium_104 -------------------------------------------AAQFSAY Mvan_0928|M.vanbaalenii_PYR-1 ----------IYPSVTSLFAFGGRCGLICDGADGTEQNPNGVGGGWLFGD : Mflv_2178|M.gilvum_PYR-GCK GGRGGD----------------------------------ATTPGRSGGH MSMEG_0868|M.smegmatis_MC2_155 GGNGGVGWAGLDGGNGGSGGLLMGIGGAGGAGGVGADGTSAHVDGGTGGT MAB_0321c|M.abscessus_ATCC_199 G-----------------------------------------PDGDAGAT TH_4332|M.thermoresistible__bu G---------------------------------------VFHEATRGGN Mb2548|M.bovis_AF2122/97 G---------------------------------------REYQTLSVRF Rv2519|M.tuberculosis_H37Rv G---------------------------------------REYQTLSVRF MUL_2395|M.ulcerans_Agy99 A---------------------------------------REYHSLSGHF MMAR_2272|M.marinum_M G---------------------------------------QQYQALAGQL MLBr_01183|M.leprae_Br4923 G---------------------------------------RQYQAHASQG MAV_1346|M.avium_104 G---------------------------------------TWYQQVSAQA Mvan_0928|M.vanbaalenii_PYR-1 GGDGWS----------------------------------STLAGIAGGK . Mflv_2178|M.gilvum_PYR-GCK GGNGG----------------------------RLWGNGGDGGNGAPGVL MSMEG_0868|M.smegmatis_MC2_155 GGTGGGTGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYV MAB_0321c|M.abscessus_ATCC_199 G-----------------------------------AQGSQGATGAAGAM TH_4332|M.thermoresistible__bu GG-------------------------------LLWGNGGKGGNGLDAGL Mb2548|M.bovis_AF2122/97 ASLDQ-----------------------------QFAQALNSAAASYQTA Rv2519|M.tuberculosis_H37Rv ASLDQ-----------------------------QFAQALNSAAASYQTA MUL_2395|M.ulcerans_Agy99 GAFNQ-----------------------------QFVQALNSASGAYASA MMAR_2272|M.marinum_M ATAYD-----------------------------QLASKLAADAAAYLGA MLBr_01183|M.leprae_Br4923 ATNHQ-----------------------------DLIQSLLTSSSAYAGT MAV_1346|M.avium_104 KAIHQ-----------------------------TLVQNLDTNADSYGAT Mvan_0928|M.vanbaalenii_PYR-1 GGAAG----------------------------LLWGSGGDGGAGGAGAA . Mflv_2178|M.gilvum_PYR-GCK GPAGTAPIPPSSLPAATG----TRGDSPPYG------------------- MSMEG_0868|M.smegmatis_MC2_155 LIAGPNVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGA MAB_0321c|M.abscessus_ATCC_199 ANCN-WIDDDCATRGGTG-------------------------------- TH_4332|M.thermoresistible__bu YTVPDPDNPGSTIQMYFEAS------------------------------ Mb2548|M.bovis_AF2122/97 EATGAS-LVQTATQGVLGVINAPTEFMFGRS------------------- Rv2519|M.tuberculosis_H37Rv EATGAS-LVQTATQGVLGVINAPTEFMFGRS------------------- MUL_2395|M.ulcerans_Agy99 EAQSAS-LLQTVGRDVLGAINAPTEFLLGRP------------------- MMAR_2272|M.marinum_M ESANANQLLSNAVNASTALVNGPFLELTGRP------------------- MLBr_01183|M.leprae_Br4923 ETAN---------------------------------------------- MAV_1346|M.avium_104 EAANRVNTSAAALQGLAPNVIPNAAPAADPP------------------- Mvan_0928|M.vanbaalenii_PYR-1 GGTGGNAGLLWGNGGHGGAGGAGVNGAVGTSG------------------ Mflv_2178|M.gilvum_PYR-GCK -----YGNLVGGDGGTGADGGRYAFGAN---------------------- MSMEG_0868|M.smegmatis_MC2_155 NGGTVDGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTA MAB_0321c|M.abscessus_ATCC_199 -----------GTGGNGGPGG----------------------------- TH_4332|M.thermoresistible__bu ------------DGADGGRGG----------------------------- Mb2548|M.bovis_AF2122/97 ---------LIGDGADG-TAASPIGEPGGI----------------LYGD Rv2519|M.tuberculosis_H37Rv ---------LIGDGADG-TAASPIGEPGGI----------------LYGD MUL_2395|M.ulcerans_Agy99 ---------LIGNGADG-TAANPNG------------------------- MMAR_2272|M.marinum_M ---------LIGNGADGYTNAQGIGTPGGAGGW-------------LYGN MLBr_01183|M.leprae_Br4923 ------------HDSL---------------------------------- MAV_1346|M.avium_104 ---------PAGTTSLG--------------------------------- Mvan_0928|M.vanbaalenii_PYR-1 --------VNNGRGGDGTAGGSGGAGGNAG-------------------- . Mflv_2178|M.gilvum_PYR-GCK ------WSLDLPVGGAGGAG-----GWANSIDGSATGGNGGD-------- MSMEG_0868|M.smegmatis_MC2_155 TGGDGGHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGG MAB_0321c|M.abscessus_ATCC_199 ------------AGGPGGHG--------GVIDFEVETFMDG--------- TH_4332|M.thermoresistible__bu --------FLFGNGGDGGNG------------GNVGGKNGADP------- Mb2548|M.bovis_AF2122/97 GGNGYSQTTPGAVGGAGGSA------------------------------ Rv2519|M.tuberculosis_H37Rv GGNGYSQTTPGAVGGAGGSA------------------------------ MUL_2395|M.ulcerans_Agy99 --------------GAGG-------------------------------- MMAR_2272|M.marinum_M GGSGGNSTHAGVAGGAGGNA------------------------------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 ----------TSIGWAQNVG------------------------------ Mvan_0928|M.vanbaalenii_PYR-1 --------LLSGRGGDGGVG------------------------------ Mflv_2178|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 AGGMGEIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTT MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4332|M.thermoresistible__bu -------------------------------------------------- Mb2548|M.bovis_AF2122/97 -------------------------------------------------- Rv2519|M.tuberculosis_H37Rv -------------------------------------------------- MUL_2395|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2272|M.marinum_M -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mvan_0928|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2178|M.gilvum_PYR-GCK ------------GGNGAFGGRGGNGG------------------------ MSMEG_0868|M.smegmatis_MC2_155 GGKASGTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGG MAB_0321c|M.abscessus_ATCC_199 ------------VTLQAKGGRGGNGG------------------------ TH_4332|M.thermoresistible__bu ------------VTATVAADKSVAGG------------------------ Mb2548|M.bovis_AF2122/97 ----------GFIGNGGAAGAGGPGA------------------------ Rv2519|M.tuberculosis_H37Rv ----------GFIGNGGAGGAGGPGA------------------------ MUL_2395|M.ulcerans_Agy99 ----------LLIGNGGSGGARGPNA------------------------ MMAR_2272|M.marinum_M ----------GLIGNGGMGGAGLRGG------------------------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 ----------AAASDFITLGEGQFAP------------------------ Mvan_0928|M.vanbaalenii_PYR-1 -------------GAGGKGGAGAHGS------------------------ Mflv_2178|M.gilvum_PYR-GCK -------AGG------------------SAYGRGGITTGGNGGAGG---- MSMEG_0868|M.smegmatis_MC2_155 AASANGAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWV MAB_0321c|M.abscessus_ATCC_199 -------------------------------------HGGAGGTGG---- TH_4332|M.thermoresistible__bu -------------------------------------NGGNGGRGG---- Mb2548|M.bovis_AF2122/97 -------------------------------------GGGTGGLGG---- Rv2519|M.tuberculosis_H37Rv -------------------------------------GGGTGGLGG---- MUL_2395|M.ulcerans_Agy99 -------------------------------------AGGPGGLGG---- MMAR_2272|M.marinum_M -------------------------------------DGGTGGLGG---- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------VPGAAGIPN---- Mvan_0928|M.vanbaalenii_PYR-1 ------------------------------DAVAAEEDGGPGGSGG---- Mflv_2178|M.gilvum_PYR-GCK ----------------------------HGSTGAAGGRGGDGA--SAS-- MSMEG_0868|M.smegmatis_MC2_155 QAYDPNGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGA--GASVW MAB_0321c|M.abscessus_ATCC_199 ----------------------------------TGGKGGDGD--DCEFG TH_4332|M.thermoresistible__bu ------------------------------LLFGLGGNGGNGG--WSTTS Mb2548|M.bovis_AF2122/97 ------------------------------WLWGNNGAAGTGD--PVNV- Rv2519|M.tuberculosis_H37Rv ------------------------------WLWGNNGAAGTGD--PVNV- MUL_2395|M.ulcerans_Agy99 ------------------------------WLYGNNGPAGTGS--PVNA- MMAR_2272|M.marinum_M ------------------------------WLWGQAGAAGTGT--PLPAN MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 ------------------------------FNPGLTAATTAGP--PAPAA Mvan_0928|M.vanbaalenii_PYR-1 -------------------------------AGGNAGAGGVGGRGALLFG Mflv_2178|M.gilvum_PYR-GCK --------GGYAVGGNGGDGGRGG----AGATG------------GTGGT MSMEG_0868|M.smegmatis_MC2_155 KANGQHSTGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGT MAB_0321c|M.abscessus_ATCC_199 -----------RTGGNGGTGGRGG-------------------------D TH_4332|M.thermoresistible__bu --------YLDARGGNGGNGGLGGVLRPGGLLS----------------L Mb2548|M.bovis_AF2122/97 AVPLRVENN-FPLVNLLVNRGPTVPILLDTGSS------SLVIPFWKIGW Rv2519|M.tuberculosis_H37Rv AVPLRVENN-FPLVNLLVNRGPTVPILLDTGSS------SLVIPFWKIGW MUL_2395|M.ulcerans_Agy99 SVPLYLDNN-FPAVNVSINGGPSVPVLLDIGSA------GLVVPIWDIGL MMAR_2272|M.marinum_M EILMRVDQYGNPVVTISVGGGPGIAVTVDTGAS------GLLVRPQDVNL MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 PAAAAGAPVLASMGRGPSIGGLSVPPSWAPGGV------APAANATPAQL Mvan_0928|M.vanbaalenii_PYR-1 RGGDGGDGGSAGTGGAGGFGGTGGAIVVTLPGGKLSDSDGAGGAGGVGGA Mflv_2178|M.gilvum_PYR-GCK GGAGGDGGRGG--LLGGHGGKG----GNAGLGGNGGTGG----------- MSMEG_0868|M.smegmatis_MC2_155 GGHGGDGGRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHT MAB_0321c|M.abscessus_ATCC_199 GNFAGTGGNGGAILVKCQHDLS---LGTHPMDVSAGTGG----------- TH_4332|M.thermoresistible__bu LLPSGAASEPGGLFTGGNGGNGGLAIANHWVGITDGVPGPDDD------- Mb2548|M.bovis_AF2122/97 QNLGLPTGFDVVHYGNG----VSIVYADVPTTVDFGGGAATTP------- Rv2519|M.tuberculosis_H37Rv QNLGLPTGFDVVHYGNG----VSIVYADVPTTVDFGGGAATTP------- MUL_2395|M.ulcerans_Agy99 QDLGLPTGFDVIRYGNG----VNILYADFNTTVDFGSGAVTAP------- MMAR_2272|M.marinum_M QSLGTPTGSGAVTYGNSSYAFNTVQYQTYQTTVNFGNGIVTNP------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 VGAGFTSAAPDTAPVTA----VPGGVPSMATAGRGGYGLGAPR------- Mvan_0928|M.vanbaalenii_PYR-1 AGLGGDGGGGGLGGLLGQAGVNGDSGATAAAGNAGGVGGAGGLGGRLPIV Mflv_2178|M.gilvum_PYR-GCK -------------------------TGGVGGDGGVG-------------- MSMEG_0868|M.smegmatis_MC2_155 GAGGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGG MAB_0321c|M.abscessus_ATCC_199 -------------------------NGGIGGGGGGG-------------- TH_4332|M.thermoresistible__bu ----------------------AVSSSAYGGHGGHG-------------- Mb2548|M.bovis_AF2122/97 ---------------------TSVHVGILPYPRNLDS------------- Rv2519|M.tuberculosis_H37Rv ---------------------TSVHVGILPYPRNLDS------------- MUL_2395|M.ulcerans_Agy99 ---------------------TSVQVGILPFPTSLQG------------- MMAR_2272|M.marinum_M ---------------------TNVAVATSATQTINGV------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 ---------------------YGVKPTVMPKPAI---------------- Mvan_0928|M.vanbaalenii_PYR-1 DLNNASPAQATLAALIKKLGLPIQAATGIQLEDVDGRLVG---------- Mflv_2178|M.gilvum_PYR-GCK ------------------------GGILTATG------------------ MSMEG_0868|M.smegmatis_MC2_155 EALIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANP MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4332|M.thermoresistible__bu -------------------------------------------------- Mb2548|M.bovis_AF2122/97 -------------------------------------------------- Rv2519|M.tuberculosis_H37Rv -------------------------------------------------- MUL_2395|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2272|M.marinum_M -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mvan_0928|M.vanbaalenii_PYR-1 --------------------------PLNAYLYNTIIGKAIFDVGNTFSS Mflv_2178|M.gilvum_PYR-GCK --------------------------------------VVGAGGSGG--- MSMEG_0868|M.smegmatis_MC2_155 QASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGI MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4332|M.thermoresistible__bu -------------------------------------------------A Mb2548|M.bovis_AF2122/97 ----------------------------------LVLIASGGAFGPNGNG Rv2519|M.tuberculosis_H37Rv ----------------------------------LVLIASGGAFGPNGNG MUL_2395|M.ulcerans_Agy99 ----------------------------------LTLIAMGNGFGPTGHG MMAR_2272|M.marinum_M ----------------------------------TTSIPLS-----SLPL MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mvan_0928|M.vanbaalenii_PYR-1 ASLSARVKEIVILSVGGQWGSEYELYAHKLAAQLFGIPADAIAALANGQA Mflv_2178|M.gilvum_PYR-GCK AGGTGGRGGD--------------------GGDGGQAG------------ MSMEG_0868|M.smegmatis_MC2_155 DGGLGGNGGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPS MAB_0321c|M.abscessus_ATCC_199 -GSVGANGAT---------------------------------------- TH_4332|M.thermoresistible__bu GPGSGGNGGS---------------------------------------- Mb2548|M.bovis_AF2122/97 ILGIGPNVGSYAVSGPGNVVTTDLPG------------------------ Rv2519|M.tuberculosis_H37Rv ILGIGPNVGSYAVSGPGNVVTTDLPG------------------------ MUL_2395|M.ulcerans_Agy99 VLGIGPNIN-VAAGGHGNVVTTALPG------------------------ MMAR_2272|M.marinum_M YLGIGPNND-FPLP---DQVTAALPG------------------------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mvan_0928|M.vanbaalenii_PYR-1 PVGLSGNELLAAQFVQELVSTRRVSDALFEAAEAAFGQTGVVDMVNLAGT Mflv_2178|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 WVQSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVAT MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4332|M.thermoresistible__bu -------------------------------------------------- Mb2548|M.bovis_AF2122/97 -------------------------------------------------- Rv2519|M.tuberculosis_H37Rv -------------------------------------------------- MUL_2395|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2272|M.marinum_M -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mvan_0928|M.vanbaalenii_PYR-1 YLGVSATLNAFKVRGPESFSAPVLPAAPSPVPASDEYGLGGRLPLIDLDT Mflv_2178|M.gilvum_PYR-GCK ----RGGAGGLAGRSGADGEAG----------------------DAGTGG MSMEG_0868|M.smegmatis_MC2_155 GNTATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGG MAB_0321c|M.abscessus_ATCC_199 -------TGVFSSSSDCS----------------------------GPGP TH_4332|M.thermoresistible__bu -----AVANSLGNAIAGNGG------------------------DAGRFV Mb2548|M.bovis_AF2122/97 ----QLNEGTLIDIPGGYMQFG---------------------PNTGTPI Rv2519|M.tuberculosis_H37Rv ----QLNEGTLIDIPGGYMQFG---------------------PNTGTPI MUL_2395|M.ulcerans_Agy99 ----QLNEGELINIPQGYMQFG---------------------PNTGTPI MMAR_2272|M.marinum_M ----DLNQGVLINTNLGYLQFG---------------------ANPLTPV MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mvan_0928|M.vanbaalenii_PYR-1 ATPAQLDLAAKIKALAVPTQQATGIELVSPDGRLIG-------PLNGYLY Mflv_2178|M.gilvum_PYR-GCK RGGAG-------------------------GSGGKGGISGTG-------- MSMEG_0868|M.smegmatis_MC2_155 NGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGG MAB_0321c|M.abscessus_ATCC_199 QPNPG--------------------------SPGDPGTSVAV-------- TH_4332|M.thermoresistible__bu LIGPG-------------------------GNGGNGGTGLXX-------- Mb2548|M.bovis_AF2122/97 TSVTGAPITVLNVQIGGYDPNGGYWSLPSIFDSGGNHGTLPAVILGTGQT Rv2519|M.tuberculosis_H37Rv TSVTGAPITVLNVQIGGYDPNGGYWSLPSIFDSGGNHGTLPAVILGTGQT MUL_2395|M.ulcerans_Agy99 TSVSGVRVHLEQSER--------------CWDGG---IQLPAAVTG---- MMAR_2272|M.marinum_M ASVTGSPVTDLQIQINNGPLQPATG---SFIDSGGLYGTIPSSLIPGVPV MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mvan_0928|M.vanbaalenii_PYR-1 NPVIGQALFEVGNAFASSSLSSRIKEIVILSVGGQWGSGYEVYAHEKVAR Mflv_2178|M.gilvum_PYR-GCK --------TPGGAGQSGQSATGRSGGAGGEG--------GAGGAGGTDD- MSMEG_0868|M.smegmatis_MC2_155 NGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGT MAB_0321c|M.abscessus_ATCC_199 ---------SGAQGNPGQAQFLIVP------------------------- TH_4332|M.thermoresistible__bu --------XPRPRRRRNHRRTRRRPNGRRPRPPPGR-------------- Mb2548|M.bovis_AF2122/97 TGYAPPGTVISISIHDNQTLLYQYTTTASNSPVVTADPRLN-TGLTPFLL Rv2519|M.tuberculosis_H37Rv TGYAPPGTVISISIHDNQTLLYQYTTTASNSPVVTADPRLN-TGLTPFLL MUL_2395|M.ulcerans_Agy99 -------CLRRFSCHDN-------ARVASTPTTLRVRPQP---------- MMAR_2272|M.marinum_M GYSVPVGTTITVYTTDGVQLYSQTVTGSTNAPLVVPSNNPFNTGNYPFLL MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mvan_0928|M.vanbaalenii_PYR-1 LVGIPEEAIVSLASGHAPVGLSGSELVAARFVQELVSTYEVSSELYHSAE Mflv_2178|M.gilvum_PYR-GCK ----------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GGTTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP---- MAB_0321c|M.abscessus_ATCC_199 ----------------------------------------- TH_4332|M.thermoresistible__bu ----------------------------------------- Mb2548|M.bovis_AF2122/97 GPVYISNNPSGVGTVVFNYPPP------------------- Rv2519|M.tuberculosis_H37Rv GPVYISNNPSGVGTVVFNYPPP------------------- MUL_2395|M.ulcerans_Agy99 ----------------------------------------- MMAR_2272|M.marinum_M GPIYISNSPTGGGQTIFDF---------------------- MLBr_01183|M.leprae_Br4923 ----------------------------------------- MAV_1346|M.avium_104 ----------------------------------------- Mvan_0928|M.vanbaalenii_PYR-1 AAFGQAGLVDLVNLASTYLGASALLNVFEVPVPTAALITTS