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ALDTPISDRRAPATTHRAMWALGDYAVLADEVLAPLGPILVSTSGIRPGDRVLDVAAGSGNASIAAAVAG AHVVACDLTPELLRSAQRRAAAAGVHLSWREANAETLPFGFNEFDAVLSTIGAMFAPRHQRTADELARVC RRGGKISVLSWTPEGFYGQLLSTLRPYRPTLPMGAPHEVWWGREEYIGDLFSDHVCDVRTQRGSLRVARF GQPEECVDYFKDYYGPTINAYRNISDDPQRVAQLDAELIELSREYLTDGVMEWEYLIFTARKR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2212 | - | - | 100% (274) | methyltransferase |
| M. marinum M | MMAR_2214 | - | 2e-96 | 60.58% (274) | methyltransferase |
| M. marinum M | MMAR_1627 | - | 2e-75 | 54.51% (266) | methyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1438c | - | 1e-126 | 78.02% (273) | putative methyltransferase |
| M. gilvum PYR-GCK | Mflv_4060 | - | 3e-69 | 50.18% (271) | methyltransferase type 11 |
| M. tuberculosis H37Rv | Rv1403c | - | 1e-126 | 78.02% (273) | putative methyltransferase |
| M. leprae Br4923 | MLBr_00551 | - | 2e-88 | 57.14% (273) | putative methyltransferase |
| M. abscessus ATCC 19977 | MAB_3930c | - | 7e-10 | 31.78% (107) | ubiquinone/menaquinone biosynthesis methlytransferase UbiE |
| M. avium 104 | MAV_3373 | - | 3e-87 | 56.20% (274) | methyltransferase, UbiE/COQ5 family protein |
| M. smegmatis MC2 155 | MSMEG_2285 | - | 3e-75 | 51.94% (258) | methyltransferase type 11 |
| M. thermoresistible (build 8) | TH_2937 | - | 4e-13 | 26.52% (264) | PUTATIVE Methyltransferase type 11 |
| M. ulcerans Agy99 | MUL_1798 | - | 1e-157 | 98.18% (274) | methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_1928 | - | 3e-68 | 48.18% (274) | methyltransferase type 11 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2212|M.marinum_M MALDTP-----ISDRRAPATTHRAMWALGDYAVLADEVLAP--LGPILVS
MUL_1798|M.ulcerans_Agy99 MALDTP-----ISDRRAPATTHWAMWALGDYAVLADEVLAP--LGPILFS
Mb1438c|M.bovis_AF2122/97 MTVYTP-----TSERQAPATTHRQMWALGDYAAIAEELLAP--LGPILVS
Rv1403c|M.tuberculosis_H37Rv MTVYTP-----TSERQAPATTHRQMWALGDYAAIAEELLAP--LGPILVS
MLBr_00551|M.leprae_Br4923 MNLYTP-----IHEDQSLAAIHRAMWALGDYALMAEEVMAP--LGPILVT
MAV_3373|M.avium_104 MTLDT------TTADASVAARHRTVWALGDYALMAEEVMAP--LGPTLVE
Mflv_4060|M.gilvum_PYR-GCK MATVDN------EDDRALKAKHRALWASGDYPAVAAELIPS--LGPELVR
Mvan_1928|M.vanbaalenii_PYR-1 MTTANAGVASDPDADRQLKAKHRALWASGDYPAVAVDLIHS--LGPRLVE
MSMEG_2285|M.smegmatis_MC2_155 MGVVTV--------DRELEAKHRALWALGNYGAIAAHIVAP--LGPVLVE
TH_2937|M.thermoresistible__bu ---------------------VTTNWAAGRYEAVGERIAPI--ADEVLDA
MAB_3930c|M.abscessus_ATCC_199 MNRATLE-----KDPHEVASMFDAVARRYDITNTVLSFGRDRFWRRATRE
.
MMAR_2212|M.marinum_M TSGIRP--GDRVLDVAAGSGNASIAAAVAGAHVVACDLTPELLRSAQRRA
MUL_1798|M.ulcerans_Agy99 TSGIRP--GDRVLDVAAGSGNASITAAVAGAHVVACDLTPELLRSAQRRA
Mb1438c|M.bovis_AF2122/97 TSGIRR--GDRVLDVAAGSGNVSIPAAMAGAHVTASDLTPELLRRAQARA
Rv1403c|M.tuberculosis_H37Rv TSGIRR--GDRVLDVAAGSGNVSIPAAMAGAHVTASDLTPELLRRAQARA
MLBr_00551|M.leprae_Br4923 ATGIRP--GMQVLDVAAGSGNISLPAAKTGATIVSTDLTPELLQRSQARA
MAV_3373|M.avium_104 AAGIGP--GVRVLDVAAGSGNITLPAAAAGASVVSTDLTPELLQRSRDRA
Mflv_4060|M.gilvum_PYR-GCK ACGVRS--GDRVLDVAAGSGNASIPAAAAGAVVTASDLTPELFDAGRRIA
Mvan_1928|M.vanbaalenii_PYR-1 ACRVGP--GQRVLDVAAGSGNAAIPAAEAGATVIAGDLTPELFEAGRETA
MSMEG_2285|M.smegmatis_MC2_155 ACGIGP--GDRVLDIAAGTGNASIPAALAGAQVTASDLCPQLVDEGAHES
TH_2937|M.thermoresistible__bu AARRTPLRGATLVDLACGTGSAALSATARGAAVTGVDITSELIALAAGKP
MAB_3930c|M.abscessus_ATCC_199 ALRLKP--GDKVLDIAAGTAVSTAELTQSGAWCVAADFSVGMLKAG----
: * ::*:*.*:. : : ** . *: :. .
MMAR_2212|M.marinum_M AAAGVHLSWREANAETLPFGFNEFDAVLSTIGAMFAPRHQRTADELARVC
MUL_1798|M.ulcerans_Agy99 AAAGVHLSWREANAETLPFGFNEFDAVLSTIGAMFAPRHQRTADELAQVC
Mb1438c|M.bovis_AF2122/97 AAAGLELGWREANAEALPFSAGEFDAVLSTIGVMFAPRHQRTADELARVC
Rv1403c|M.tuberculosis_H37Rv AAAGLELGWREANAEALPFSAGEFDAVLSTIGVMFAPRHQRTADELARVC
MLBr_00551|M.leprae_Br4923 TELGLTLEYREADAQALPFGDGEFDVVMSAIGVMFAPDHRRAASELVRVC
MAV_3373|M.avium_104 AGMGLTIDYREANAQALPFGDGEFDAVVSAIGVQFAPDHQRAADELVRVC
Mflv_4060|M.gilvum_PYR-GCK AERGVAVEWVEADAEALPFPDDSFDVVMSCVGAMFAPHHQATADEIVRVT
Mvan_1928|M.vanbaalenii_PYR-1 RRRGVEVQWMEADAEAMPFADNDFDVVMSCVGAMFAPHHQATADELVRVT
MSMEG_2285|M.smegmatis_MC2_155 AERGVDITWKEANAEALPFSDGEFDVVMSCIGVMFAPHHDQSARELLRVT
TH_2937|M.thermoresistible__bu G--GSTVTWVTADAADTGLKTASFDVAVSNMGIIFVP-PDRQVAELARLL
MAB_3930c|M.abscessus_ATCC_199 --ARRDVPKVAGDATRLPFADHSFDAVTISFGLRNVVDHVEGLREMARVT
: .:* : .**.. .* . *: ::
MMAR_2212|M.marinum_M RRGGKISVLSWTPEGFYGQLLSTLRPYRPTLPMGAPHEVWWGREEYIGDL
MUL_1798|M.ulcerans_Agy99 RRGGKISVLSWTPEGFYGQLLSTLRPYRPTLPMGAPHEVWWGREEYIGDL
Mb1438c|M.bovis_AF2122/97 RRGGKISTLNWTPEGFYGKLLSTIRPYRPTLPAGAPHEVWWGSEDYVSGL
Rv1403c|M.tuberculosis_H37Rv RRGGKISTLNWTPEGFYGKLLSTIRPYRPTLPAGAPHEVWWGSEDYVSGL
MLBr_00551|M.leprae_Br4923 RPNGTIGVISWTQEGFFGRMLATIRPYRPSLSAALPPAALWGREAYIRGL
MAV_3373|M.avium_104 RPGGRIGLISWTPEGFFGRMLATIRPYRPSLSHPVPPAALWGRPGYVRAL
Mflv_4060|M.gilvum_PYR-GCK RPGGTLGLISWTPEGFIGHLFATMKPYAPPPPPGASPPPMWGSENHVEAL
Mvan_1928|M.vanbaalenii_PYR-1 RPGGTIGLINWTPEGFIGNLFATMKPYAPPPPPGASPAPLWGNAEHVREL
MSMEG_2285|M.smegmatis_MC2_155 RSGGRIGLISWTPEGFIGQLFATMKPFVPAPPPGVSPPPLWGNADHVRTL
TH_2937|M.thermoresistible__bu KPGGVLSFSAWIRTDEN-PFSDPVAEVLGPPPAGFSPD-QWGDAETLTER
MAB_3930c|M.abscessus_ATCC_199 KPGGRLAVCEFS--------TPVNRPFR----------------TLYMEY
: .* :. :
MMAR_2212|M.marinum_M FSDHVCDVRTQRGSLRVARFGQPEECVDYFKDYYGPTINAYRNISDDPQR
MUL_1798|M.ulcerans_Agy99 FSDHVCDVRTQRGSLRVKRFGQPEECVDYFKDYYGPTINAYRNISDDPQR
Mb1438c|M.bovis_AF2122/97 FRDHVSDIRTRRGSLTVDRFGCPDECRDYFKNFYGPAINAYRSIADSPEC
Rv1403c|M.tuberculosis_H37Rv FRDHVSDIRTRRGSLTVDRFGCPDECRDYFKNFYGPAINAYRSIADSPEC
MLBr_00551|M.leprae_Br4923 LDDTVTNVKTERRQLEVKRFNSAEGVHNYFKNHYGPTIEAYTNIGDNSVL
MAV_3373|M.avium_104 LGERIGEITTARGMLPVNRFGSAEDVHAYFKQHYGPTIEAYANIGHNRVL
Mflv_4060|M.gilvum_PYR-GCK FGDRVRDLTMRRQTVRFDHCASPLDFREYWKRNYGPTLAAYRFNEDRPER
Mvan_1928|M.vanbaalenii_PYR-1 FADRVTDLQMQRQTVVMDHCATPLEFREYWKANYGPTIATYRFNADDAER
MSMEG_2285|M.smegmatis_MC2_155 LGDGIEDFETQRRSLTVDMFADGAAFRDFFKANYGPTIAAYRAVGDDAER
TH_2937|M.thermoresistible__bu LTPHFDAIDLIRG-LHPWEFDSPATALHFLRTESPVHVEIFRRAG--PAR
MAB_3930c|M.abscessus_ATCC_199 LMKTLPEVARAVSSNPDAYVYLAESIRAWPDQE--ALAHQIASAGWSNVR
: . . :
MMAR_2212|M.marinum_M VAQLDAELIELSREYLTDG-----VMEWEYLIFTARKR--
MUL_1798|M.ulcerans_Agy99 VAQLDAELIELSREYLTDG-----VMEWEYLIFTARKR--
Mb1438c|M.bovis_AF2122/97 VATLDAEITELCREYLCDG-----VMQWEYLIFTARKC--
Rv1403c|M.tuberculosis_H37Rv VATLDAEITELCREYLCDG-----VMQWEYLIFTARKC--
MLBr_00551|M.leprae_Br4923 AAELDAQLTELAQKYLTNS-----TMGWEYLLLTAQKH--
MAV_3373|M.avium_104 AAELDAQLVELAAQHLSDG-----TMGWEYLLVTAEKRSG
Mflv_4060|M.gilvum_PYR-GCK LAELDAAFLDFLTTWNQADGTDGTAYDAEYLLVTATKR--
Mvan_1928|M.vanbaalenii_PYR-1 VAALDRDFLAFLEQWNQSGETGRTAYEAEYLLVTATKR--
MSMEG_2285|M.smegmatis_MC2_155 TAALDEAIALLGDRYLDSG-----AMQWEYLVVTAHKR--
TH_2937|M.thermoresistible__bu RERLAAAFRSALRPHAGPAG--TVGFTAPYVIVTARRRG-
MAB_3930c|M.abscessus_ATCC_199 WRNLTGGIVALHIATL------------------------
* :