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MGVVTVDRELEAKHRALWALGNYGAIAAHIVAPLGPVLVEACGIGPGDRVLDIAAGTGNASIPAALAGAQ VTASDLCPQLVDEGAHESAERGVDITWKEANAEALPFSDGEFDVVMSCIGVMFAPHHDQSARELLRVTRS GGRIGLISWTPEGFIGQLFATMKPFVPAPPPGVSPPPLWGNADHVRTLLGDGIEDFETQRRSLTVDMFAD GAAFRDFFKANYGPTIAAYRAVGDDAERTAALDEAIALLGDRYLDSGAMQWEYLVVTAHKR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2285 | - | - | 100% (271) | methyltransferase type 11 |
| M. smegmatis MC2 155 | MSMEG_1005 | - | e-158 | 100.00% (271) | methyltransferase type 11 |
| M. smegmatis MC2 155 | MSMEG_1893 | - | 4e-21 | 29.17% (264) | UbiE/COQ5 methyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1438c | - | 1e-77 | 53.56% (267) | putative methyltransferase |
| M. gilvum PYR-GCK | Mflv_4060 | - | 3e-88 | 58.89% (270) | methyltransferase type 11 |
| M. tuberculosis H37Rv | Rv1403c | - | 1e-77 | 53.56% (267) | putative methyltransferase |
| M. leprae Br4923 | MLBr_00551 | - | 2e-73 | 48.48% (264) | putative methyltransferase |
| M. abscessus ATCC 19977 | MAB_3930c | - | 4e-12 | 34.23% (111) | ubiquinone/menaquinone biosynthesis methlytransferase UbiE |
| M. marinum M | MMAR_1627 | - | 8e-96 | 62.78% (266) | methyltransferase |
| M. avium 104 | MAV_3373 | - | 1e-76 | 50.55% (271) | methyltransferase, UbiE/COQ5 family protein |
| M. thermoresistible (build 8) | TH_2937 | - | 5e-16 | 32.35% (170) | PUTATIVE Methyltransferase type 11 |
| M. ulcerans Agy99 | MUL_3409 | - | 4e-95 | 62.41% (266) | methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_1928 | - | 9e-92 | 59.26% (270) | methyltransferase type 11 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1438c|M.bovis_AF2122/97 MTVYTP-----TSERQAPATTHRQMWALGDYAAIAEELLAPLGPILVSTS
Rv1403c|M.tuberculosis_H37Rv MTVYTP-----TSERQAPATTHRQMWALGDYAAIAEELLAPLGPILVSTS
MLBr_00551|M.leprae_Br4923 MNLYTP-----IHEDQSLAAIHRAMWALGDYALMAEEVMAPLGPILVTAT
MAV_3373|M.avium_104 MTLDT------TTADASVAARHRTVWALGDYALMAEEVMAPLGPTLVEAA
MMAR_1627|M.marinum_M MTTLAR----TEPTDRGYESKHRALWALGDYPAVATDLVSPLGPILLEAT
MUL_3409|M.ulcerans_Agy99 MTTLAR----TEPTDRGYESKHRALWALGDYPAVATDLVSPLGPILLEAT
MSMEG_2285|M.smegmatis_MC2_155 MGVVT--------VDRELEAKHRALWALGNYGAIAAHIVAPLGPVLVEAC
Mflv_4060|M.gilvum_PYR-GCK MATVDN------EDDRALKAKHRALWASGDYPAVAAELIPSLGPELVRAC
Mvan_1928|M.vanbaalenii_PYR-1 MTTANAGVASDPDADRQLKAKHRALWASGDYPAVAVDLIHSLGPRLVEAC
TH_2937|M.thermoresistible__bu ---------------------VTTNWAAGRYEAVGERIAPIADEVLDAAA
MAB_3930c|M.abscessus_ATCC_199 MNRATLE-----KDPHEVASMFDAVARRYDITNTVLSFGRDRFWRRATRE
.
Mb1438c|M.bovis_AF2122/97 GIR--RGDRVLDVAAGSGNVSIPAAMAGAHVTASDLTPELLRRAQARAAA
Rv1403c|M.tuberculosis_H37Rv GIR--RGDRVLDVAAGSGNVSIPAAMAGAHVTASDLTPELLRRAQARAAA
MLBr_00551|M.leprae_Br4923 GIR--PGMQVLDVAAGSGNISLPAAKTGATIVSTDLTPELLQRSQARATE
MAV_3373|M.avium_104 GIG--PGVRVLDVAAGSGNITLPAAAAGASVVSTDLTPELLQRSRDRAAG
MMAR_1627|M.marinum_M RIS--AGDRVLDVAAGSGNVAIPAALAGADVIASDLCPNLLECGRGLAAA
MUL_3409|M.ulcerans_Agy99 RIS--AGDRVLDVAAGSGNVAIPAALAGADVIASDLCPNLLECGRGLAAA
MSMEG_2285|M.smegmatis_MC2_155 GIG--PGDRVLDIAAGTGNASIPAALAGAQVTASDLCPQLVDEGAHESAE
Mflv_4060|M.gilvum_PYR-GCK GVR--SGDRVLDVAAGSGNASIPAAAAGAVVTASDLTPELFDAGRRIAAE
Mvan_1928|M.vanbaalenii_PYR-1 RVG--PGQRVLDVAAGSGNAAIPAAEAGATVIAGDLTPELFEAGRETARR
TH_2937|M.thermoresistible__bu RRTPLRGATLVDLACGTGSAALSATARGAAVTGVDITSELIALAAGKPG-
MAB_3930c|M.abscessus_ATCC_199 ALRLKPGDKVLDIAAGTAVSTAELTQSGAWCVAADFSVGMLKAG------
* ::*:*.*:. : : ** . *: :. .
Mb1438c|M.bovis_AF2122/97 AGLELGWREANAEALPFSAGEFDAVLSTIGVMFAPRHQRTADELARVCRR
Rv1403c|M.tuberculosis_H37Rv AGLELGWREANAEALPFSAGEFDAVLSTIGVMFAPRHQRTADELARVCRR
MLBr_00551|M.leprae_Br4923 LGLTLEYREADAQALPFGDGEFDVVMSAIGVMFAPDHRRAASELVRVCRP
MAV_3373|M.avium_104 MGLTIDYREANAQALPFGDGEFDAVVSAIGVQFAPDHQRAADELVRVCRP
MMAR_1627|M.marinum_M RGASLRWVEANAQALPFDTDEFDAVVSCVGVMFAPYHQPCADELVRVCRP
MUL_3409|M.ulcerans_Agy99 RGASLRWVEANAQALPFDTDEFDAVVSCVGVMFAPYHQPCADGLVRVCRP
MSMEG_2285|M.smegmatis_MC2_155 RGVDITWKEANAEALPFSDGEFDVVMSCIGVMFAPHHDQSARELLRVTRS
Mflv_4060|M.gilvum_PYR-GCK RGVAVEWVEADAEALPFPDDSFDVVMSCVGAMFAPHHQATADEIVRVTRP
Mvan_1928|M.vanbaalenii_PYR-1 RGVEVQWMEADAEAMPFADNDFDVVMSCVGAMFAPHHQATADELVRVTRP
TH_2937|M.thermoresistible__bu -GSTVTWVTADAADTGLKTASFDVAVSNMGIIFVP-PDRQVAELARLLKP
MAB_3930c|M.abscessus_ATCC_199 ARRDVPKVAGDATRLPFADHSFDAVTISFGLRNVVDHVEGLREMARVTKP
: .:* : .**.. .* . : *: :
Mb1438c|M.bovis_AF2122/97 GGKISTLNWTPEGFYGKLLSTIRPYRPTLPAGAPHEVWWGSEDYVSGLFR
Rv1403c|M.tuberculosis_H37Rv GGKISTLNWTPEGFYGKLLSTIRPYRPTLPAGAPHEVWWGSEDYVSGLFR
MLBr_00551|M.leprae_Br4923 NGTIGVISWTQEGFFGRMLATIRPYRPSLSAALPPAALWGREAYIRGLLD
MAV_3373|M.avium_104 GGRIGLISWTPEGFFGRMLATIRPYRPSLSHPVPPAALWGRPGYVRALLG
MMAR_1627|M.marinum_M GGVIGLISWTPGGFIGEMFTTMKPYLAPPLPGAQPAPLWGTEGHVRELFA
MUL_3409|M.ulcerans_Agy99 GGVIGLISWTPGGFIGEMFTTMKPYLAPPLPGAQPAPLWGTEGHVRELFA
MSMEG_2285|M.smegmatis_MC2_155 GGRIGLISWTPEGFIGQLFATMKPFVPAPPPGVSPPPLWGNADHVRTLLG
Mflv_4060|M.gilvum_PYR-GCK GGTLGLISWTPEGFIGHLFATMKPYAPPPPPGASPPPMWGSENHVEALFG
Mvan_1928|M.vanbaalenii_PYR-1 GGTIGLINWTPEGFIGNLFATMKPYAPPPPPGASPAPLWGNAEHVRELFA
TH_2937|M.thermoresistible__bu GGVLSFSAWIRTDEN-PFSDPVAEVLGPPPAGFSPD-QWGDAETLTERLT
MAB_3930c|M.abscessus_ATCC_199 GGRLAVCEFS-TPVNRPFRTLYMEYLMKTLPEVARAVSSNPDAYV--YLA
.* :. : : . : :
Mb1438c|M.bovis_AF2122/97 DHVSDIRTRRGSLTVDRFGCPDECRDYFKNFYGPAINAYRSIADSPECVA
Rv1403c|M.tuberculosis_H37Rv DHVSDIRTRRGSLTVDRFGCPDECRDYFKNFYGPAINAYRSIADSPECVA
MLBr_00551|M.leprae_Br4923 DTVTNVKTERRQLEVKRFNSAEGVHNYFKNHYGPTIEAYTNIGDNSVLAA
MAV_3373|M.avium_104 ERIGEITTARGMLPVNRFGSAEDVHAYFKQHYGPTIEAYANIGHNRVLAA
MMAR_1627|M.marinum_M DRVTDFAVRRGALLVDEFADGASFRDYFKANYGPTIAAYRAIAAEPDRVA
MUL_3409|M.ulcerans_Agy99 DRVTDFAVRRGTLLVDEFADGASFRDYFKANYGPTIAAYRAIAAEPDRVA
MSMEG_2285|M.smegmatis_MC2_155 DGIEDFETQRRSLTVDMFADGAAFRDFFKANYGPTIAAYRAVGDDAERTA
Mflv_4060|M.gilvum_PYR-GCK DRVRDLTMRRQTVRFDHCASPLDFREYWKRNYGPTLAAYRFNEDRPERLA
Mvan_1928|M.vanbaalenii_PYR-1 DRVTDLQMQRQTVVMDHCATPLEFREYWKANYGPTIATYRFNADDAERVA
TH_2937|M.thermoresistible__bu PHFDAIDLIRG-LHPWEFDSPATALHFLRTESPVHVEIFRRAG--PARRE
MAB_3930c|M.abscessus_ATCC_199 ESIRAWP--DQEALAHQIASAGWSNVRWRNLTGGIVALHIATL-------
. : : .
Mb1438c|M.bovis_AF2122/97 TLDAEITELCREYLCD-----GVMQWEYLIFTARKC--
Rv1403c|M.tuberculosis_H37Rv TLDAEITELCREYLCD-----GVMQWEYLIFTARKC--
MLBr_00551|M.leprae_Br4923 ELDAQLTELAQKYLTN-----STMGWEYLLLTAQKH--
MAV_3373|M.avium_104 ELDAQLVELAAQHLSD-----GTMGWEYLLVTAEKRSG
MMAR_1627|M.marinum_M ALDAELAALGDRYLAG----SSAMEWEYLLVTARKR--
MUL_3409|M.ulcerans_Agy99 ALDAELAALGDRYLAG----SSAMEWEYLLVTARKR--
MSMEG_2285|M.smegmatis_MC2_155 ALDEAIALLGDRYLD-----SGAMQWEYLVVTAHKR--
Mflv_4060|M.gilvum_PYR-GCK ELDAAFLDFLTTWNQADGTDGTAYDAEYLLVTATKR--
Mvan_1928|M.vanbaalenii_PYR-1 ALDRDFLAFLEQWNQSGETGRTAYEAEYLLVTATKR--
TH_2937|M.thermoresistible__bu RLAAAFRSALRPHAGPAG--TVGFTAPYVIVTARRRG-
MAB_3930c|M.abscessus_ATCC_199 --------------------------------------