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M. marinum M MMAR_1738 (-)

annotation: oxidoreductase
coordinates: 2090704 - 2091636
length: 310

MRALRAHRRGGPETLAVERAPVPVPAAGEVVVAVRAAGITFDELTWDQTWTRDGVSRTPVIPSHEVSGVI
HEIGSGTEDFHCGDEVYGLIGFDRDGAAADFVAVPAAHLAAKPATISHTVAAALPLAGLTALQALVDHAA
VRPGEAVLVHGGAGGVGALVVQLAAILGANVTATVRSDAGELVSRLGAQRVIDTRTEAFERTATDFDVVI
DTVGGDTLDRSFAVLRPGGRLVTLSAPPPAGKADEHGVTAMFFIVTPNRDQLNRLGELVGSGRLHVEIAQ
SFPLANGREAFESGRGAARRAGKTVITVGQ
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_1738--100% (310)oxidoreductase
M. marinum MMMAR_2814fadB53e-3335.47% (234) oxidoreductase FadB5
M. marinum MMMAR_2259qor9e-2830.72% (319) quinone reductase Qor

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1947cfadB52e-3135.04% (234) oxidoreductase FADB5
M. gilvum PYR-GCKMflv_2124-6e-3333.64% (321) alcohol dehydrogenase
M. tuberculosis H37RvRv1912cfadB52e-3135.04% (234) oxidoreductase FADB5
M. leprae Br4923MLBr_00135-4e-2133.20% (250) putative polyketide synthase
M. abscessus ATCC 19977MAB_3307c-6e-5640.45% (309) putative zinc-binding oxidoreductase
M. avium 104MAV_3325-9e-2829.60% (321) quinone oxidoreductase
M. smegmatis MC2 155MSMEG_5762-5e-6043.55% (310) zinc-binding oxidoreductase
M. thermoresistible (build 8)TH_3440-1e-2829.91% (321) PUTATIVE Alcohol dehydrogenase, zinc-binding domain protein
M. ulcerans Agy99MUL_2935fadB51e-3135.04% (234) oxidoreductase FadB5
M. vanbaalenii PYR-1Mvan_5758-5e-3336.08% (316) alcohol dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MAV_3325|M.avium_104                --------------------------------------------------
TH_3440|M.thermoresistible__bu      --------------------------------------------------
MAB_3307c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5762|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1738|M.marinum_M               --------------------------------------------------
Mflv_2124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5758|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          MTASVEGADQKSEKLISYLKKVVVELDETRARLREYEQRATEPVAVVGIG
                                                                                      

Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MAV_3325|M.avium_104                --------------------------------------------------
TH_3440|M.thermoresistible__bu      --------------------------------------------------
MAB_3307c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5762|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1738|M.marinum_M               --------------------------------------------------
Mflv_2124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5758|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          CRFPGGVDSPDRLWDVVSECRDVVSEFPTDRGWDVDGLFDPDPDAEGKTY
                                                                                      

Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MAV_3325|M.avium_104                --------------------------------------------------
TH_3440|M.thermoresistible__bu      --------------------------------------------------
MAB_3307c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5762|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1738|M.marinum_M               --------------------------------------------------
Mflv_2124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5758|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          TRWGAFLDDAAGFDAGFFGIAPSEVLAMDPQQRLMLEVSWEALEYAGIDP
                                                                                      

Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MAV_3325|M.avium_104                --------------------------------------------------
TH_3440|M.thermoresistible__bu      --------------------------------------------------
MAB_3307c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5762|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1738|M.marinum_M               --------------------------------------------------
Mflv_2124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5758|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          LSLRGSATGVFTGIFAPSYGSRDTGGLQGYGLTGTAVSVASGRVSYVLGL
                                                                                      

Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MAV_3325|M.avium_104                --------------------------------------------------
TH_3440|M.thermoresistible__bu      --------------------------------------------------
MAB_3307c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5762|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1738|M.marinum_M               --------------------------------------------------
Mflv_2124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5758|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          EGPAVSVDTACSSSLVAIHWAMSSLRSGECDLALAGGVTVMGLPSIFVGF
                                                                                      

Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MAV_3325|M.avium_104                --------------------------------------------------
TH_3440|M.thermoresistible__bu      --------------------------------------------------
MAB_3307c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5762|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1738|M.marinum_M               --------------------------------------------------
Mflv_2124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5758|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          SRQRGLAADGRCKAFARAADGTGWGEGAGVVVLERLSDAQRLGHTVLAVV
                                                                                      

Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MAV_3325|M.avium_104                --------------------------------------------------
TH_3440|M.thermoresistible__bu      --------------------------------------------------
MAB_3307c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5762|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1738|M.marinum_M               --------------------------------------------------
Mflv_2124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5758|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          RGSAVNQDGASNGLTAPNGLAQQRVIQAALTNAGLSSADVDVVEAHGTAT
                                                                                      

Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MAV_3325|M.avium_104                --------------------------------------------------
TH_3440|M.thermoresistible__bu      --------------------------------------------------
MAB_3307c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5762|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1738|M.marinum_M               --------------------------------------------------
Mflv_2124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5758|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          TLGDPIEAQALLATYGQGRPADQPLWVGSIKSNMGHTQAAAGVAGVIKMV
                                                                                      

Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MAV_3325|M.avium_104                --------------------------------------------------
TH_3440|M.thermoresistible__bu      --------------------------------------------------
MAB_3307c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5762|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1738|M.marinum_M               --------------------------------------------------
Mflv_2124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5758|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          QAMRHHVMPATLHVDEPSPRVDWTTGAVSVLTEARDWSVEGRPRRAGVSS
                                                                                      

Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MAV_3325|M.avium_104                --------------------------------------------------
TH_3440|M.thermoresistible__bu      --------------------------------------------------
MAB_3307c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5762|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1738|M.marinum_M               --------------------------------------------------
Mflv_2124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5758|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          FGISGTNAHVILEEAPTPVEASYSTADQQRLSVVPWVVSGRSTAALMAQA
                                                                                      

Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MAV_3325|M.avium_104                --------------------------------------------------
TH_3440|M.thermoresistible__bu      --------------------------------------------------
MAB_3307c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5762|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1738|M.marinum_M               --------------------------------------------------
Mflv_2124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5758|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          SRLAFYVQADPEVDPVDVGCALAARSVFEHRAVVVGESREQLIAGLAGLA
                                                                                      

Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MAV_3325|M.avium_104                --------------------------------------------------
TH_3440|M.thermoresistible__bu      --------------------------------------------------
MAB_3307c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5762|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1738|M.marinum_M               --------------------------------------------------
Mflv_2124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5758|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          VGESGAGVAIGQAAPLGKTVVVFPGQGAQRIGMGRELCSQLPVFAEEFDA
                                                                                      

Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MAV_3325|M.avium_104                --------------------------------------------------
TH_3440|M.thermoresistible__bu      --------------------------------------------------
MAB_3307c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5762|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1738|M.marinum_M               --------------------------------------------------
Mflv_2124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5758|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          VTGELDRHMRLPLRDVVWGADAGLLDSTEFAQPALFAVEVALFAVLQHWG
                                                                                      

Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MAV_3325|M.avium_104                --------------------------------------------------
TH_3440|M.thermoresistible__bu      --------------------------------------------------
MAB_3307c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5762|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1738|M.marinum_M               --------------------------------------------------
Mflv_2124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5758|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          LQPDFVMGHSIGELAAAYVAGVLAPADAAMLVVARGRLMQSMPAGGTMWA
                                                                                      

Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MAV_3325|M.avium_104                --------------------------------------------------
TH_3440|M.thermoresistible__bu      --------------------------------------------------
MAB_3307c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5762|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1738|M.marinum_M               --------------------------------------------------
Mflv_2124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5758|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          VAASEDEVVSLLGEGVGIAAINAPESVVISGPQAAVSAIADKFAAQGRRV
                                                                                      

Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MAV_3325|M.avium_104                --------------------------------------------------
TH_3440|M.thermoresistible__bu      --------------------------------------------------
MAB_3307c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5762|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1738|M.marinum_M               --------------------------------------------------
Mflv_2124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5758|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          HQLAVSHAFHSPLMEPMLEEFVRVAAQVEVRKPQIGLVSNVTGELAGPDF
                                                                                      

Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MAV_3325|M.avium_104                --------------------------------------------------
TH_3440|M.thermoresistible__bu      --------------------------------------------------
MAB_3307c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5762|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1738|M.marinum_M               --------------------------------------------------
Mflv_2124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5758|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          GSPQYWGEHVSRAVRFVDSARHLQTLGATHFIESGPSSGLMGAIEQSLAP
                                                                                      

Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MAV_3325|M.avium_104                --------------------------------------------------
TH_3440|M.thermoresistible__bu      --------------------------------------------------
MAB_3307c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5762|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1738|M.marinum_M               --------------------------------------------------
Mflv_2124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5758|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          AEAVVVSMMGKDRPELASVLGAAGQLFATGMPVEWPAVFAGSSRRRVTLP
                                                                                      

Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MAV_3325|M.avium_104                --------------------------------------------------
TH_3440|M.thermoresistible__bu      --------------------------------------------------
MAB_3307c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5762|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1738|M.marinum_M               --------------------------------------------------
Mflv_2124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5758|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          TYAFQRRRFWETPGTDGTASVSGLGLGSTEHALLGAVVERPDSGGVVLTG
                                                                                      

Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MAV_3325|M.avium_104                --------------------------------------------------
TH_3440|M.thermoresistible__bu      --------------------------------------------------
MAB_3307c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5762|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1738|M.marinum_M               --------------------------------------------------
Mflv_2124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5758|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          RLSLANQPWLADHVIGGVVLFPGAGFVELVIRAGDEVGCAGVEELVLAAP
                                                                                      

Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MAV_3325|M.avium_104                --------------------------------------------------
TH_3440|M.thermoresistible__bu      --------------------------------------------------
MAB_3307c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5762|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1738|M.marinum_M               --------------------------------------------------
Mflv_2124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5758|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          LVLHPGSGVQVQVVVAAADESSRRAVSVYSRGDQSHGGWLLNAEGLLEVD
                                                                                      

Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MAV_3325|M.avium_104                --------------------------------------------------
TH_3440|M.thermoresistible__bu      --------------------------------------------------
MAB_3307c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5762|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1738|M.marinum_M               --------------------------------------------------
Mflv_2124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5758|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          AAEATVDLSLWPPEGAESVDISDAYPQLAERGYAYGPAFQGLVAIWRRGS
                                                                                      

Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MAV_3325|M.avium_104                --------------------------------------------------
TH_3440|M.thermoresistible__bu      --------------------------------------------------
MAB_3307c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5762|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1738|M.marinum_M               --------------------------------------------------
Mflv_2124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5758|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          ELFAEVVAPTGVVVDGMGMHPALLDAVLHALGLAIENTQATTEMRLPFCW
                                                                                      

Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MAV_3325|M.avium_104                --------------------------------------------------
TH_3440|M.thermoresistible__bu      --------------------------------------------------
MAB_3307c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5762|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1738|M.marinum_M               --------------------------------------------------
Mflv_2124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5758|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          RGVSLHAGGAGRVRARFTSAGADAIAVDIADSAGLPVLTVRSLVTRAMTA
                                                                                      

Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MAV_3325|M.avium_104                --------------------------------------------------
TH_3440|M.thermoresistible__bu      --------------------------------------------------
MAB_3307c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5762|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1738|M.marinum_M               --------------------------------------------------
Mflv_2124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5758|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          EQLRTAVTAAGGALEQGPMDLVWSPIPLSSDGHGGGLPSVVSWADYCAGR
                                                                                      

Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MAV_3325|M.avium_104                --------------------------------------------------
TH_3440|M.thermoresistible__bu      --------------------------------------------------
MAB_3307c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5762|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1738|M.marinum_M               --------------------------------------------------
Mflv_2124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5758|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          GNDTGVVVWEFGSASAGAQAPVDSVAAVYSATHAALQVLQFWFGQDRAGT
                                                                                      

Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MAV_3325|M.avium_104                --------------------------------------------------
TH_3440|M.thermoresistible__bu      ---------------------------------------VQTAAAQRRDE
MAB_3307c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5762|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1738|M.marinum_M               --------------------------------------------------
Mflv_2124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5758|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          LVVLTRGAVGLVGEGISDLAAAAVWGMVRSAQSEHSGKIVLIDTDSAVDV
                                                                                      

Mb1947c|M.bovis_AF2122/97           ------------------------------------MRAVVITK-HGDPS
Rv1912c|M.tuberculosis_H37Rv        ------------------------------------MRAVVITK-HGDPS
MUL_2935|M.ulcerans_Agy99           ------------------------------------MRAVVITK-HGDPS
MAV_3325|M.avium_104                ------------------------------------MHAIEVSE-TGGPE
TH_3440|M.thermoresistible__bu      IGVIGVALRAVRTTGQNDPRMEHIRAGELHTGMIGAMKAIEVRE-TGGPE
MAB_3307c|M.abscessus_ATCC_199      ------------------------------------MKAIVAEQGAKG-A
MSMEG_5762|M.smegmatis_MC2_155      ------------------------------------MRAIIAKDRTAGID
MMAR_1738|M.marinum_M               ------------------------------------MRALRAHR-RGGPE
Mflv_2124|M.gilvum_PYR-GCK          --------------------------------MSDRMKAVVLAR-FGGAD
Mvan_5758|M.vanbaalenii_PYR-1       ------------------------------------MRAAVLTA---YNS
MLBr_00135|M.leprae_Br4923          AVLADLGESQLLVRCNTVHAARLSPAPQLLALPVGESMWRLAADGGGTLE
                                                                                      

Mb1947c|M.bovis_AF2122/97           VLQVRQRPDPPPP-GPGQLRVAVRAAGVNFADHLARVGLYPDAPKLPAVV
Rv1912c|M.tuberculosis_H37Rv        VLQVRQRPDPPPP-GPGQLRVAVRAAGVNFADHLARVGLYPDAPKLPAVV
MUL_2935|M.ulcerans_Agy99           VLQVQQRPDPPPP-GPGQLRIAVRAAGVNFADHLARVGLYPDAPKLPAVV
MAV_3325|M.avium_104                VLRYVETPTPTA--GPGQVLIKAEAIGVNYIDTYFRSGQYP--RELPFII
TH_3440|M.thermoresistible__bu      VLTYVDVPEPTP--GPGQVLIKAEAIGVNFIDTYFRSGLYP--REVPFIV
MAB_3307c|M.abscessus_ATCC_199      GLSLTAVPYPHAAENDVIVQVHAAGFTPGELDWPGTWADRSGRSRGPSIP
MSMEG_5762|M.smegmatis_MC2_155      GLALAEVPYPHAAENDVIVAVHAAAFTPGELDWPGTWTDRAGRDRTPSVP
MMAR_1738|M.marinum_M               TLAVERAPVPVPAAGEVVVAVRAAGITFDELTWDQTWT-RDGVSRTPVIP
Mflv_2124|M.gilvum_PYR-GCK          AFELRDVAVPHVGPRQVRVRVHATAVNP--LDYQIRRGDYTDLVPLPAII
Mvan_5758|M.vanbaalenii_PYR-1       PLLVDELPDPEPGPGEVLVRVMASGVNPLDIKIR-RGEAPHAQLPPPAVL
MLBr_00135|M.leprae_Br4923          DLVIQPCPEVQAPLQAGHMRVAVAAVGVNFRDVVAALGMYPG---QAPPL
                                     :     .          : : . .                     .   

Mb1947c|M.bovis_AF2122/97           GYEVAGTVEAVGDGVDPNRVGERVLAG-----TRFGGYCEIVNVAATDSV
Rv1912c|M.tuberculosis_H37Rv        GYEVAGTVEAVGDGVDPNRVGERVLAG-----TRFGGYCEIVNVAATDSV
MUL_2935|M.ulcerans_Agy99           GYEVAGTVEAAGAGVDESRIGERVLAG-----TRFGGYSEIVNVTATDSV
MAV_3325|M.avium_104                GQELCGTVAAAGDGVDGFKVGDRVVSA-----AATGGYAEYATAPASLTA
TH_3440|M.thermoresistible__bu      GTEVCGTVEAVGDGVAALRVGDRVLTD-----KANGAYAEYTVAPADYVA
MAB_3307c|M.abscessus_ATCC_199      GHEVSGIVVELGYGTTGLTVGQRVFGITD-WTRN-GALAQYVAVEARNLA
MSMEG_5762|M.smegmatis_MC2_155      GHEVSGVVAELGFGTTGLAVGQRVFGLTD-WCRN-GTLAEYVAVEARNLA
MMAR_1738|M.marinum_M               SHEVSGVIHEIGSGTEDFHCGDEVYGLIG-FDRD-GAAADFVAVPAAHLA
Mflv_2124|M.gilvum_PYR-GCK          GHDISGVIEEVGSHVTEFRAGDAVYYTPK-IFGGPGSYAEQHVADVDLVG
Mvan_5758|M.vanbaalenii_PYR-1       GIDMAGVVEAVGPRVDRFTVGDEVFGMTGGVGGLQGSLAELAAVDARLIA
MLBr_00135|M.leprae_Br4923          GAEGAGVVIEIGPEVTGVAVGDAVMGFLG-------GAGPLAVVHQQLIT
                                    . : .* :   *  .     *: *                   .      

Mb1947c|M.bovis_AF2122/97           VLPDALSFEQGAAVPVNYATAWAALHGYGSLRAGERVLIHAAAGGVGIAA
Rv1912c|M.tuberculosis_H37Rv        VLPDALSFEQGAAVPVNYATAWAALHGYGSLRAGERVLIHAAAGGVGIAA
MUL_2935|M.ulcerans_Agy99           VLPEGLSFEQGAAVPVNYATAWAALHGYGSLRAGERVLVHAAAGGVGIAA
MAV_3325|M.avium_104                HVPDGVAADVAASALLKGLTAHYLLTSVYPVQAGDTVLVHAGAGGVGLIL
TH_3440|M.thermoresistible__bu      YVPDGVAPDTVASALLKGMTAHYLIKSVYEVQRGDTILVHAGAGGVGLIL
MAB_3307c|M.abscessus_ATCC_199      PLSADVDHTVAAALPVSGLTAWQGLFLHGHIVAGQSVLIHGAAGAVGSVA
MSMEG_5762|M.smegmatis_MC2_155      PLSATIDHTTAAALPISGLTAWQGLFTHGHLTPGETVLIHGAAGGVGSIA
MMAR_1738|M.marinum_M               AKPATISHTVAAALPLAGLTALQALVDHAAVRPGEAVLVHGGAGGVGALV
Mflv_2124|M.gilvum_PYR-GCK          RKPDNLDHLEAASLTLVGGTVWESLVTRAQLTVGETILIHGGAGGVGTIA
Mvan_5758|M.vanbaalenii_PYR-1       HKPRTLSMAQAAALPLGFITSWEGLVDRAGVGTGQQVLIHGGAGGVGFLA
MLBr_00135|M.leprae_Br4923          QMPQGWSLAEAAAVPVVFLTALFGLADLAGIRAGESVLIHAGTGGVGMAA
                                      .        *:  :   *    :     :  *: :*:*..:*.**   

Mb1947c|M.bovis_AF2122/97           VQFAKAAKAEVHGTAS-------PQKHQKLAEFGVDRAIDYRRD------
Rv1912c|M.tuberculosis_H37Rv        VQFAKAAKAEVHGTAS-------PQKHQKLAEFGVDRAIDYRRD------
MUL_2935|M.ulcerans_Agy99           VQFAKAAGAQVHGTAS-------PGKHQRLAELGVDRAIDYRRD------
MAV_3325|M.avium_104                TQWAHLLGARVITTVST------PEKARRSAQAGANEVLSYPDDADEFGN
TH_3440|M.thermoresistible__bu      TQWATHLGARVITTVST------PQKAELSRKAGAAEVLDYPTDPEEFGA
MAB_3307c|M.abscessus_ATCC_199      VQLAHEAGAHVIGTGR-------GGQRDQVLGLKADDFVDLTTDTLEDIG
MSMEG_5762|M.smegmatis_MC2_155      VQLAREAGAHVIGSGR-------TADREYVLEVGAEAFVDLEHDRLEDVG
MMAR_1738|M.marinum_M               VQLAAILGANVTATVR-------SDAGELVSRLGAQRVIDTRTEAFERTA
Mflv_2124|M.gilvum_PYR-GCK          IQVAKAMGARVITTAK-------AGDHAFVNSLGADVAIDHTSTDYVDAV
Mvan_5758|M.vanbaalenii_PYR-1       VQLALARGAQVYATGS--------TSSQAVIRAAGAVPIDYTATTVDEYV
MLBr_00135|M.leprae_Br4923          VQFARHWGVEIFVTASRGKWDTLRDMGFDDDHIGDSRTLEFEEKFLAVTD
                                     * *    ..:  :                        :.          

Mb1947c|M.bovis_AF2122/97           ------GWWQGLGPYDVVLDALGGTSLRRSYTLLR----------PGGRL
Rv1912c|M.tuberculosis_H37Rv        ------GWWQGLGPYDVVLDALGGTSLRRSYTLLR----------PGGRL
MUL_2935|M.ulcerans_Agy99           ------GWWKGLDSYDLVLDALGDTYLRRSYELLR----------PGGRL
MAV_3325|M.avium_104                RI----RALTDGAGVAAVYDGVGASTFDASLASLA----------VRGTL
TH_3440|M.thermoresistible__bu      RI----RDLTGGEGVPVVYDGVGRSTFDASLASLA----------VRGTL
MAB_3307c|M.abscessus_ATCC_199      -------------QVDVVFDVIGGEILDRSAQLVR----------AGG--
MSMEG_5762|M.smegmatis_MC2_155      -------------EVDLVLDVIGGQILYRSAALVR----------PTG--
MMAR_1738|M.marinum_M               T------------DFDVVIDTVGGDTLDRSFAVLR----------PGG--
Mflv_2124|M.gilvum_PYR-GCK          AEATRG------RGVDVVFDTIGGDTLTRSPLSLA----------DSGRV
Mvan_5758|M.vanbaalenii_PYR-1       AAHTG------GEGFDVVADNVGGATLDASFTAVKR--------YTGHVV
MLBr_00135|M.leprae_Br4923          -----------GRGVDVVLDSLAGDFVDASLRLLVRGGRFLEMGKTDIRD
                                                     * * :.   .  *   :                

Mb1947c|M.bovis_AF2122/97           VGYGISNMQHGEKRSMRRVAPHALSMLRGFNLMKQLEESKTVI-------
Rv1912c|M.tuberculosis_H37Rv        VGYGISNMQHGEKRSMRRVAPHALSMLRGFNLMKQLEESKTVI-------
MUL_2935|M.ulcerans_Agy99           VGYGVSNMQEGEKRSLRRVAPHALSMLRGFNLMKQLEESKTVI-------
MAV_3325|M.avium_104                ALFGAASGPVPPFDPQRLNAAGSVFLTR----------------------
TH_3440|M.thermoresistible__bu      ALFGAASGPVPPFDPQRLNAAGSVYLTR----------------------
MAB_3307c|M.abscessus_ATCC_199      -ALITIAEPP---RVIPEGARAVFFVVE----------------------
MSMEG_5762|M.smegmatis_MC2_155      -SVVSIVEPP---RIPADNGRAVFFVVE----------------------
MMAR_1738|M.marinum_M               -RLVTLSAPPPAGKADEHGVTAMFFIVT----------------------
Mflv_2124|M.gilvum_PYR-GCK          VSIVDIARPQNLIEAWGRNAAYHFVFTR----------------------
Mvan_5758|M.vanbaalenii_PYR-1       SALGWGTHSLAPLSFRGAAYSGVFTLMP----------------------
MLBr_00135|M.leprae_Br4923          AQEIAANYPGVQYRAFDLSEAGPVRMQEMLCEVRELFDTQVLHRLPVTSW
                                                           . .                        

Mb1947c|M.bovis_AF2122/97           ----GLNMLRLWDDRRTLEPWIAPLTKALNDGTILPIVH-----------
Rv1912c|M.tuberculosis_H37Rv        ----GLNMLRLWDDRRTLEPWIAPLTKALNDGTILPIVH-----------
MUL_2935|M.ulcerans_Agy99           ----GLNMLRLWDDRGTLEPWIAPLSEALGQGTAAPIVH-----------
MAV_3325|M.avium_104                -----PSLAHFIRTGQEFSWRAEELFAAIAAGDITVEVG-----------
TH_3440|M.thermoresistible__bu      -----PSLVHFTRTPDEFGWRAGEFLSAVADGTLTITVG-----------
MAB_3307c|M.abscessus_ATCC_199      ----------------ADRRQLTILENKLRDGRIRQNIG-----------
MSMEG_5762|M.smegmatis_MC2_155      ----------------PDRAGLVELEQRLRDGRLRPRVG-----------
MMAR_1738|M.marinum_M               ----------------PNRDQLNRLGELVGSGRLHVEIA-----------
Mflv_2124|M.gilvum_PYR-GCK          ----------------QNRGKLDALTMLVERGLVKPVLG-----------
Mvan_5758|M.vanbaalenii_PYR-1       --------LLTGRGRDHHGEIVAEAAALADSGRLAPRLHP----------
MLBr_00135|M.leprae_Br4923          DVRCAPAAFRFMSQARHIGKVVLTMPSALADGLAEGTVLITGASGAIGGV
                                                                   *     :            

Mb1947c|M.bovis_AF2122/97           -AIVPFAEAPEAHRILAAR---ENVGKVVLVP------------------
Rv1912c|M.tuberculosis_H37Rv        -AIVPFAEAPEAHRILAAR---ENVDKVVLVP------------------
MUL_2935|M.ulcerans_Agy99           -AAIPFAEAPEAHRILAAR---ENIGKVVLVP------------------
MAV_3325|M.avium_104                -GRYPLADAARAHRDLQGR---KTTGSIVLLP------------------
TH_3440|M.thermoresistible__bu      -ERYPLAEAERAHRDLEGR---KTVGSVVLLP------------------
MAB_3307c|M.abscessus_ATCC_199      -SVIPLEDALSAFDIDR-----KTPGKTIVQIAAV---------------
MSMEG_5762|M.smegmatis_MC2_155      -TVYPLADAKEAFAPAQ-----RPRGKSVIRVIEES--------------
MMAR_1738|M.marinum_M               -QSFPLANGREAFESGRG--AARRAGKTVITVGQ----------------
Mflv_2124|M.gilvum_PYR-GCK          -ATLPLARMGEAHELLENRRSYALRGKVAIDVAGETVALPPRIS------
Mvan_5758|M.vanbaalenii_PYR-1       -TTFPLDAVNDAHTAVESG---SATGKVVVEPNV----------------
MLBr_00135|M.leprae_Br4923          LARHMVSAYGVRHLVLASRRGDRAEGAVELAAELVGAGAKIQVVACDVAD
                                         .      .            .   :                    

Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MAV_3325|M.avium_104                --------------------------------------------------
TH_3440|M.thermoresistible__bu      --------------------------------------------------
MAB_3307c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5762|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1738|M.marinum_M               --------------------------------------------------
Mflv_2124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5758|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          NDAVRGLFAQLSREFPPVRGVIHAAGVLDDGAITSLTPDRVDTVLRAKVD
                                                                                      

Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MAV_3325|M.avium_104                --------------------------------------------------
TH_3440|M.thermoresistible__bu      --------------------------------------------------
MAB_3307c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5762|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1738|M.marinum_M               --------------------------------------------------
Mflv_2124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5758|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          AAWNLHEATRDLDLLMFVLCSSIAATVGSPGQGNYSAANAFLDGLAAYRQ
                                                                                      

Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MAV_3325|M.avium_104                --------------------------------------------------
TH_3440|M.thermoresistible__bu      --------------------------------------------------
MAB_3307c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5762|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1738|M.marinum_M               --------------------------------------------------
Mflv_2124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5758|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          AAGLAGTSLAWGLWEQPGGMNAHLSSRDLARISRSGLAPMNPAQALELFD
                                                                                      

Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MAV_3325|M.avium_104                --------------------------------------------------
TH_3440|M.thermoresistible__bu      --------------------------------------------------
MAB_3307c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5762|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1738|M.marinum_M               --------------------------------------------------
Mflv_2124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5758|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          AALVIDHPFMVTALLDRAALDAQAQAGALPPLFSRLVRRSRRRQIEDPGD
                                                                                      

Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MAV_3325|M.avium_104                --------------------------------------------------
TH_3440|M.thermoresistible__bu      --------------------------------------------------
MAB_3307c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5762|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1738|M.marinum_M               --------------------------------------------------
Mflv_2124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5758|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          ATQSKLALVQRLQGLAANRQLELLVGVVCLQAAAVLGRPSPEDIDPNTKF
                                                                                      

Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MAV_3325|M.avium_104                --------------------------------------------------
TH_3440|M.thermoresistible__bu      --------------------------------------------------
MAB_3307c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5762|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1738|M.marinum_M               --------------------------------------------------
Mflv_2124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5758|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00135|M.leprae_Br4923          QDLGFDSLTAVELRNRLKSATGLTLPPTVIFDHPTPTAVAEYVAQQMLKS
                                                                                      

Mb1947c|M.bovis_AF2122/97           ------------------------
Rv1912c|M.tuberculosis_H37Rv        ------------------------
MUL_2935|M.ulcerans_Agy99           ------------------------
MAV_3325|M.avium_104                ------------------------
TH_3440|M.thermoresistible__bu      ------------------------
MAB_3307c|M.abscessus_ATCC_199      ------------------------
MSMEG_5762|M.smegmatis_MC2_155      ------------------------
MMAR_1738|M.marinum_M               ------------------------
Mflv_2124|M.gilvum_PYR-GCK          ------------------------
Mvan_5758|M.vanbaalenii_PYR-1       ------------------------
MLBr_00135|M.leprae_Br4923          RPAESGDETSQAVEPKVEEVSVHA