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MRAVVITKHGDPSVLQVRQRPDPPPPGPGQLRVAVRAAGVNFADHLARVGLYPDAPKLPAVVGYEVAGTV EAVGDGVDPNRVGERVLAGTRFGGYCEIVNVAATDSVVLPDALSFEQGAAVPVNYATAWAALHGYGSLRA GERVLIHAAAGGVGIAAVQFAKAAKAEVHGTASPQKHQKLAEFGVDRAIDYRRDGWWQGLGPYDVVLDAL GGTSLRRSYTLLRPGGRLVGYGISNMQHGEKRSMRRVAPHALSMLRGFNLMKQLEESKTVIGLNMLRLWD DRRTLEPWIAPLTKALNDGTILPIVHAIVPFAEAPEAHRILAARENVGKVVLVP
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1947c | fadB5 | - | 100% (334) | oxidoreductase FADB5 |
M. bovis AF2122 / 97 | Mb2965c | mas | 5e-35 | 31.86% (339) | multifunctional mycocerosic acid synthase membrane-associated |
M. bovis AF2122 / 97 | Mb3855c | pks2 | 3e-34 | 34.28% (318) | polyketide synthase PKS2 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_1189 | - | 9e-40 | 36.17% (329) | alcohol dehydrogenase |
M. tuberculosis H37Rv | Rv1912c | fadB5 | 0.0 | 99.70% (334) | oxidoreductase FADB5 |
M. leprae Br4923 | MLBr_01229 | pks3 | 7e-34 | 37.85% (251) | mycocerosic acid synthase (polyketide synthase) |
M. abscessus ATCC 19977 | MAB_1112c | - | 3e-43 | 35.48% (341) | putative quinone oxidoreductase |
M. marinum M | MMAR_2814 | fadB5 | 1e-174 | 88.62% (334) | oxidoreductase FadB5 |
M. avium 104 | MAV_0242 | - | 2e-35 | 34.49% (316) | quinone oxidoreductase |
M. smegmatis MC2 155 | MSMEG_6362 | - | 1e-35 | 34.26% (324) | quinone oxidoreductase |
M. thermoresistible (build 8) | TH_4621 | - | 2e-38 | 36.31% (325) | PUTATIVE mycocerosic acid synthase |
M. ulcerans Agy99 | MUL_2935 | fadB5 | 1e-173 | 88.92% (334) | oxidoreductase FadB5 |
M. vanbaalenii PYR-1 | Mvan_5615 | - | 1e-36 | 36.66% (311) | alcohol dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 ---MRAANVTPVAVIGMACRLPGGIDSPQRLWEALLRGDDLVTEIPKERW TH_4621|M.thermoresistible__bu VNIVGDTPVNAVAVIGMACRLPGGIDSPQRLWEALLRGDDMVTEIPVDRW Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 DADLYYDPEPGVPGRSVSRWGAFLDDVGGFDCDFFGMTEREAIAIDPQHR TH_4621|M.thermoresistible__bu DADDYFDPEPGVPGRTVSRWGAFLDDVAGFDPEFFGISEREAISIDPQQR Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 LLLETSWDAIEHAGLDPATLAGSATGVFVGLTHGDYELLSADCGATEGPY TH_4621|M.thermoresistible__bu LLLETSWEAMEHAGLTPADVEGSSTGVFVGLSHDDYALLTSDAGALEEAY Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 GFTGTSNSFASGRVAYTLGLHGPAVTVDTACSSGLMAVHQARGSLDCGES TH_4621|M.thermoresistible__bu GFTGSAFSMASGRIAYRLGVHGPAVTVDTACSSSLLAVHMACRSLQVGES Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 DLALAGGVVVTLEPRKSVSGSLQGMLSPTGRCHAFDVAADGFVSGEGCVV TH_4621|M.thermoresistible__bu DLALAGGAMVMLEPRKYTSASGLGMLSPTGRCHAFDVAADGFVRSEGSVM Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 LLLKRMPDAERDGDRILAVLRGTAANQDGHTVHIAAPSEQAQIAVYHKAL TH_4621|M.thermoresistible__bu LLLKRLPDALRDNDRILAVVRGTAANQDGRTENISTPSIQAQADVYRSAL Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 AVGGVDPTTVGLIEAHGTGTPVGDPIEYASLAAVYGTAGRCALASTKTNF TH_4621|M.thermoresistible__bu AVAGVDPATVGMVEAHGTGTPVGDPIEYNSLTQVYGKTGPCALTSVKTNF Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 GHMQSTSGPLGMMKAILALQHGVVPKNLHFTRLPDQLAEITTELFVPQVN TH_4621|M.thermoresistible__bu GHAESAAGALGMMKAILALQHGVVPQNLHFTRLPDEMAAIETNLFVPQAT Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 TPWPVDVQQPRRAAVSSYGMSGTNVHAILEQAPENSGK-DSPAVSKVNGP TH_4621|M.thermoresistible__bu TLWPVREGCPRRAAVSSYGMSGTNVHAVLEQAPEPVQRPEESADTDAAGP Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 LLFPLSATSVEQLRATAARMADWVDEHGSGTKHTGLWDLGYTLSRRRGYR TH_4621|M.thermoresistible__bu LVFALSSTSAEELRRTAGRLAEWVEAH---TDEVVPADLAYTLARRRAHR Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 PVRTMVLASSFAELSRGLREIAGSEIPYQSAVGQDDRGPVWVFSGQGSQW TH_4621|M.thermoresistible__bu PVRTTVIADGVEALTAGLREVADGDAPYQPAVGMDDKAPVWVFSGQGSQW Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 AGMGAELFAKEPVFAAAIAAMEPVIVEESGFSVTEALTVAEKVTGIDRVQ TH_4621|M.thermoresistible__bu AGMGAELLATEQVFAAKIAEIEPLVARESGFSVTEAMTASETVTGIDRVQ Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 PTIFAIQVALAATMKSYGVYPGAVIGHSLGEAAAAVAAGALSCEDGLRVI TH_4621|M.thermoresistible__bu PTLFAIQVALAATMQSYGVRPGAVIGHSLGEVAAAVVAGALSLEDGVKVI Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 CRRSQLMSRVAGSGAMASVELPGQQVLSELSIRGLSDVVLAVVASPTSTV TH_4621|M.thermoresistible__bu CRRSRLCLRLAGAGAMAAIELPAQAVREFLAARGVDDVVLSVIASPESTV Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 VGGDTQAIRHLLAAWQAQDVMVREVAVDVASHTPQVEPILDDLVETLADL TH_4621|M.thermoresistible__bu IGGATDTVRELVAAWEAQGVMAREVAVDVASHSPQVDPILDELEEILADL Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 KPTEPKVPYYSATLWDPRERPSFTGEYWAENLRYTVRFAAAVQAALKDGF TH_4621|M.thermoresistible__bu QPMTPTVPYYSATSYDPREKPVCDADYWVDNLRHEVRFAAAVQAALEDGF Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 RVFGELAPHPLLTYAIEQNAASLDMPVSALAAMRREQELPFGLRGFIADV TH_4621|M.thermoresistible__bu RVFGELSPHPLLTRAVEQTARGLDMPVAALPAMRREQEMPHGVRTMVGDL Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 HSAGALVDFSVQYPNGCLVDAPLPTWTRRELMLSRESVDHPAHGAAVQAV TH_4621|M.thermoresistible__bu FAAGAAVDFAALYPSGRLVDAPLPTWTRRKLVLSRENGEQQTRGGCTITV Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 HPLLGAHVHLFEEPERHVWQGRVGTEAHPWLGDHQIHDVAAFPGAAYCEM TH_4621|M.thermoresistible__bu HPLLGTHVRLPEEPERHVWQADLGTGAQPWLADHQIHTVAALPGAAYCEM Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 ALTAARVTLG-EASEVRDIKFEQTLLLDRETMASSAATVSAPGVLEFAVE TH_4621|M.thermoresistible__bu ALAAAREVIDSDGVEVRDVRFEQMLLLDEQTEVSAVASAVEPGTLEFAVE Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 TYEEGERVRRASAVLRALEDRVNQQPASHSIDALIASHPLRTEGADLRAT TH_4621|M.thermoresistible__bu TAKDGEHERRATAVLGAADD--TEPPQAHDIDALLAEHPTRIEGDELRQW Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 FDAIGIQYGLAFSGLTAVYTAAGTNEDVSTVLAEVALPGAIRSQQASYTS TH_4621|M.thermoresistible__bu FDQRGVQFGPAFTGLTAARIPEGT---VTSVLAEVGLPGQIRSQQAPYGI Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 HPALLDACFQSVIVAPEVQKAGAGGLLLPVYVRRLLNYHSMRNAQYCLTR TH_4621|M.thermoresistible__bu HPALLDACFQSVAAHPDVQGAGSG-LLLPLGVRRLQAFGPTRGARYCYAR Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 VKTSRAGECEVDLEVLDQSGAVLLLVEGLRLAGGASEHECANRVLDERLF TH_4621|M.thermoresistible__bu VTDADGSKAEADLDVLDEHGNVLLRVQGLLMGGAAADGDDRDRVLGERLL Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 TVEWEPRELPEVTQRERGSWLVLGASAEDPLVQQLGDALNADGGHCTAVS TH_4621|M.thermoresistible__bu TIEWQRRDLPEADSAAGKWLLVSTSATADVSATRLSDALKQAGAESTSMC Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 LPLGQIDTAQLCSLLSRDGVSSSIGHGALKGLTGVVVVTAPPATVAESPA TH_4621|M.thermoresistible__bu WPQ-QADHADNVDRFR---------AGIADGVTGVVVLTGPKNGNPDDAA Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 LRRGRDYVSHLITIVREISELPGERPRLFVVTRNAASIKTGDLANLEQVG TH_4621|M.thermoresistible__bu ARRGSDYVRHLVRITRELAEIDGDAPRLFVVTRGAQAVLPQDRPNLEQAG Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 LRGLIRVIDSEHPYLSVTQIDVEETNQATIATQVARQLRSGSDEDETGWR TH_4621|M.thermoresistible__bu LRGLLRVIGAEHPHLRTTQIDIADD---ADLDRVAVQLLGGGAEDETAWR Mb1947c|M.bovis_AF2122/97 ------------------MRAVVITKHGDPSVLQVRQRPDPP-------- Rv1912c|M.tuberculosis_H37Rv ------------------MRAVVITKHGDPSVLQVRQRPDPP-------- MMAR_2814|M.marinum_M ------------------MRAVVITRHGDPSVLQVQQRPDPP-------- MUL_2935|M.ulcerans_Agy99 ------------------MRAVVITKHGDPSVLQVQQRPDPP-------- MAV_0242|M.avium_104 ---------------MATMRAIVAE---SADQLSWQEVADV--------- MSMEG_6362|M.smegmatis_MC2_155 ------------------MHAIVAS---VNGGLNWENVASI--------- Mflv_1189|M.gilvum_PYR-GCK ----------------------MAE---TPDQLNWQSVPDP--------- Mvan_5615|M.vanbaalenii_PYR-1 -----------------MHAIVAQP---SSEGLTWQSVPDI--------- MAB_1112c|M.abscessus_ATCC_199 ------------------MYAITLNGFGDPEVMQWTQVADLP-------- MLBr_01229|M.leprae_Br4923 DGEWYTARLRPGPLRQAERRTVVVQNEHDGMRLEIRTPGDLDSLEFVAFD TH_4621|M.thermoresistible__bu DGQWYTARLSLSPLRPEERKQAVVDCERDGMRLEIRTPGDLETMELAAFD : . Mb1947c|M.bovis_AF2122/97 --PPGPGQLRVAVRAAGVNFADHLARVGLYPDAPKLPAVVGYEVAGTVEA Rv1912c|M.tuberculosis_H37Rv --PPGPGQLRVAVRAAGVNFADHLARVGLYPDAPKLPAVVGYEVAGTVEA MMAR_2814|M.marinum_M --PPGPGQLRISVRAAGVNFADHLARVGLYPDAPKLPAVVGYEVAGTVEA MUL_2935|M.ulcerans_Agy99 --PPGPGQLRIAVRAAGVNFADHLARVGLYPDAPKLPAVVGYEVAGTVEA MAV_0242|M.avium_104 --SAGPGEVVVKVAAAGVNRADVLQAAGKYPPPPGASETIGMEVSGVIAE MSMEG_6362|M.smegmatis_MC2_155 --APANGEVLIKVHTAGINRADLLQAAGKYPPPPGASEVIGLEVSGTVEA Mflv_1189|M.gilvum_PYR-GCK --TPGPGEVLIRVHAAGVNRADLLQAAGKYPPPPGASEIIGLEASGTIAA Mvan_5615|M.vanbaalenii_PYR-1 --APAPGEVLIRVAAAGVNRADLLQAAGKYPPPPGASDILGLEVSGTIAA MAB_1112c|M.abscessus_ATCC_199 --APGPGEVTIDVVAAGVNRADVMQRLGLYPPPPGVSEIPGLEVSGHIAE MLBr_01229|M.leprae_Br4923 RVPPGPGEIEVAVTASTVNFADVLVAFGRYPTFEGYCQLLGIDFAGVVSA TH_4621|M.thermoresistible__bu RVPPGPGQIEVAVTASSINFADVLIAFGRYPTFDGRRPQLGTDFAGVVTA ... *:: : * :: :* ** : * ** * : :* : Mb1947c|M.bovis_AF2122/97 VGDGVDPNRVGERVLAGTRFGGYCEIVNVAATDSVVLPDALSFEQGAAVP Rv1912c|M.tuberculosis_H37Rv VGDGVDPNRVGERVLAGTRFGGYCEIVNVAATDSVVLPDALSFEQGAAVP MMAR_2814|M.marinum_M VGAGVDESRIGERVLAGTRFGGYSEIVNVTATDAVVLPEGLSFEQGAAVP MUL_2935|M.ulcerans_Agy99 AGAGVDESRIGERVLAGTRFGGYSEIVNVTATDSVVLPEGLSFEQGAAVP MAV_0242|M.avium_104 VGDGVTEWSVGQEVCALLAGGGYAEYVAVPAGQLLPIPAGVDLVDAAGLP MSMEG_6362|M.smegmatis_MC2_155 LGDGVSGWSVGQPVCALLAGGGYAEYVAVPAPQVLPVPDGVSLRDAAGLP Mflv_1189|M.gilvum_PYR-GCK VGDGVTEWSEGQRVCALLAGGGYAEYVAVPAGQVLPVPDGVPLDHAAGLP Mvan_5615|M.vanbaalenii_PYR-1 IGEGVTKWSQGQPVCALLAGGGYAEFVAVPAGQVLPIPDGVPVPHAAGLP MAB_1112c|M.abscessus_ATCC_199 VGPAVQGWVPGDAVCALMAGGGYAERVNVAATQVLPVPRGVSITAAAALP MLBr_01229|M.leprae_Br4923 VGLNVTDHKVGDRVGGVSRNGCWTTFVICDARHAVTLSPEVPLEEAAAVP TH_4621|M.thermoresistible__bu VGPDVTSHRVGDRVGGLSPNGCWSTFVTCDADLAVPLPDGLTEGQAAAVS * * *: * . * : * * : :. : .*.:. Mb1947c|M.bovis_AF2122/97 VNYATAWAALHGYGSLRAGERVLIHAAAGGVGIAAVQFAKAAKAEVHGTA Rv1912c|M.tuberculosis_H37Rv VNYATAWAALHGYGSLRAGERVLIHAAAGGVGIAAVQFAKAAKAEVHGTA MMAR_2814|M.marinum_M VNYATAWAALHGYGSLRAGERVLVHAAAGGVGIAAVQFAKAAGAQVHGTA MUL_2935|M.ulcerans_Agy99 VNYATAWAALHGYGSLRAGERVLVHAAAGGVGIAAVQFAKAAGAQVHGTA MAV_0242|M.avium_104 EVACTVWSNLVLIAGLRNGQLLLVHGGASGIGSHAIQVARALGARVAVTA MSMEG_6362|M.smegmatis_MC2_155 EVACTVWSNVVMTAGLTAGHLLLVHGGASGIGTHAIQVAKAMGARVAVTA Mflv_1189|M.gilvum_PYR-GCK EVACTVWSNLVMTARLRAPELLLIHGGASGIGTHAIQVARALNCRVAVTA Mvan_5615|M.vanbaalenii_PYR-1 EVACTVWSNVVMAAGLTAPELLLVHGGASGIGTHAIQVAKALNCRVAVTA MAB_1112c|M.abscessus_ATCC_199 ETAATVWSNVVMTGGLRSGQTLLIHGGGSGIGTHAIQVGRALGANVAVTA MLBr_01229|M.leprae_Br4923 TVAATAWYGLHDLARISQTDKVLIHSGTGGVGQAAIAIARAAGCEIFATA TH_4621|M.thermoresistible__bu TAHATAWYGLHDLARLGAGEKVLIHSATGGVGLAAIAIARSVGAQIYATA .*.* : . : . :*:*.. .*:* *: ..:: ..: ** Mb1947c|M.bovis_AF2122/97 SPQ-KHQKLAEFGVDRAIDYRRDGWWQGLGPYD-------VVLDALGGTS Rv1912c|M.tuberculosis_H37Rv SPQ-KHQKLAEFGVDRAIDYRRDGWWQGLGPYD-------VVLDALGGTS MMAR_2814|M.marinum_M SPG-KHQRLAELGVDRAIDYRRDGWWKGLDSYD-------LVLDALGGTS MUL_2935|M.ulcerans_Agy99 SPG-KHQRLAELGVDRAIDYRRDGWWKGLDSYD-------LVLDALGDTY MAV_0242|M.avium_104 GSAEKLGFCRELGADITINYRDEDFVARLADETG---GADVILDIMGAAY MSMEG_6362|M.smegmatis_MC2_155 GSEEKLGICRDLGADITINYREEDFVERLRRETD---GADVILDIMGAAY Mflv_1189|M.gilvum_PYR-GCK GSRNKLDLCAELGAEITIDYHHEDFVEVLRGADSDHPGADVILDIMGASY Mvan_5615|M.vanbaalenii_PYR-1 GSRNKLDLCAELGADITIDYHNEDYVGVVRDAG----GADVILDIMGAAY MAB_1112c|M.abscessus_ATCC_199 GTQFKLDRCRELGAHTLINYREQDFPAVVNAAYS---GANVILDIVGGGY MLBr_01229|M.leprae_Br4923 GSPQRRQLLRDKGIEHVYDSRSLEFAEQIHRDTKG-YGVDVVLNSLPGAA TH_4621|M.thermoresistible__bu GSPARRDLLRDMGIEHVYDSRSTAFADEIRRDTDG-YGVDVVLNSLPGAA .. : : * . : : : : ::*: : Mb1947c|M.bovis_AF2122/97 LRRSYTLLRPGGRLVGYGISNMQHGEKRSMRRVAPHALSMLRGFNLMKQL Rv1912c|M.tuberculosis_H37Rv LRRSYTLLRPGGRLVGYGISNMQHGEKRSMRRVAPHALSMLRGFNLMKQL MMAR_2814|M.marinum_M LRRSYELLRPGGRLVGYGVSNMQEGEKRSLRRVAPHALSMLRGFNLMKQL MUL_2935|M.ulcerans_Agy99 LRRSYELLRPGGRLVGYGVSNMQEGEKRSLRRVAPHALSMLRGFNLMKQL MAV_0242|M.avium_104 LDRNIDALATDGQLV---IIGMQGGVKAELN----IGKLLAKRARVIGTT MSMEG_6362|M.smegmatis_MC2_155 LDRNVDALATGGRLV---IIGMQGGVKAELN----IGKLLGKRAGVIATS Mflv_1189|M.gilvum_PYR-GCK LDRNIDALATGGRLV---IIGMQGGTKAEIN----LGKLLAKRGSVMATA Mvan_5615|M.vanbaalenii_PYR-1 LDRNIETLADGGRLV---IIGMQGGAKAELN----IGKLLTKRGSVIATA MAB_1112c|M.abscessus_ATCC_199 LAKNVEALAENGHLT---IIGLQGGAAAELN----LGALLFKRGSVHATN MLBr_01229|M.leprae_Br4923 QRAGIELLAFGGRFVEIGKRDIYGDTRLGLFP-------FRRNLSLYAVD TH_4621|M.thermoresistible__bu QRAGLELLSFGGRFIEIGKRDIYGDTRLGLFP-------FRRNLAFHGVD . * .*:: .: . : : : . Mb1947c|M.bovis_AF2122/97 EESKTVIGLNMLRLWDDRRTLEPWIAPLTKALNDGTILPIVHAIVPFAEA Rv1912c|M.tuberculosis_H37Rv EESKTVIGLNMLRLWDDRRTLEPWIAPLTKALNDGTILPIVHAIVPFAEA MMAR_2814|M.marinum_M EESKTVIGLNMLRLWDDRGTLEPWIAPLSEALDQGTAAPIVHAAIPFGEA MUL_2935|M.ulcerans_Agy99 EESKTVIGLNMLRLWDDRGTLEPWIAPLSEALGQGTAAPIVHAAIPFAEA MAV_0242|M.avium_104 LRGRPVSGP-----NSKTEIVQAVTASVWPMIADGRVRPIIGARLPIQQA MSMEG_6362|M.smegmatis_MC2_155 LRPRPVDGP-----GGKGEIVRAVRENVWPMIADGRVKPIIGAELPIENA Mflv_1189|M.gilvum_PYR-GCK LRSRPVTGR-----GSKSVIVSEVIENVWPLVADGQVRPVIGAEFPISEA Mvan_5615|M.vanbaalenii_PYR-1 LRSRPVHGR-----GGKADIVARVGAELWPLVADGQVRPVIGAEFPIAEA MAB_1112c|M.abscessus_ATCC_199 LRRRPEQGP-----GSKAEIIAELRQHLWPLIAEGTVAPVVSAEVPVTDA MLBr_01229|M.leprae_Br4923 LALLTYTHP---------DTVRRLLTTVYQRTAEGVLPVPQTTHYPIHNT TH_4621|M.thermoresistible__bu LGLMADSHP---------HKIRELLETVYRLTADGVLPMPQSTHYPLAEA . : : :* : *. :: Mb1947c|M.bovis_AF2122/97 PEAHRILAARENVGKVVLVP------------------------------ Rv1912c|M.tuberculosis_H37Rv PEAHRILAARENVDKVVLVP------------------------------ MMAR_2814|M.marinum_M PEAHRILAARENIGKVVLVP------------------------------ MUL_2935|M.ulcerans_Agy99 PEAHRILAARENIGKVVLVP------------------------------ MAV_0242|M.avium_104 GDAHRRLVASEVTGKIVLTV------------------------------ MSMEG_6362|M.smegmatis_MC2_155 QQGHDLLASGKVTGKVLLRVSE---------------------------- Mflv_1189|M.gilvum_PYR-GCK QAAHELLASGDVSGKVILRVDV---------------------------- Mvan_5615|M.vanbaalenii_PYR-1 QAAHELLASGDVSGKVLLRVDV---------------------------- MAB_1112c|M.abscessus_ATCC_199 AEAHRLLDSPETVGKVLLTVRRQ--------------------------- MLBr_01229|M.leprae_Br4923 ANAVRLVAGAGHTGKVLLDVPHTGSSVAVVPPEQVRTFRADGAYIVTGGL TH_4621|M.thermoresistible__bu ATAIRVMSAAEHVGKLVLDVPHTGRADVVVPPEQASPFRSDGAYIVTGGM . : . .*::* Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 TGLGLFLGTEMAAAGCGRIVLNSRSAPNPQAQETIERLRAGGADIQVECG TH_4621|M.thermoresistible__bu GGLGLYLAGEMAAAGAGCIVLNGRSAPSGEALRTIEQLRAAGTEVIVECG Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 DIAEPRVADRLVVAATQSGLPVRGVLHAAGVVEDATLTNVTDDLIDRCWA TH_4621|M.thermoresistible__bu XX--------------XRGQPVEVAVPTELRHADEHPDRRGAQLCDEFAR Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 PKVYGAWNLHQALQ-EGKTAQLLDWFCSFSTAAALVGSPGQGAYAAANSW TH_4621|M.thermoresistible__bu GEQGAQRNQHRTDAGEGQRD---------AHPPGAVGHDQPDPGALSDTG Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 LDGFSYWRRAQGLASTTIAWGAWGELGLATALAEMAGVAIAPTEGARVFQ TH_4621|M.thermoresistible__bu LD---------------ERGGQFPGVGVQIPVADPG-VGIDHRGAVRVDS Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 TLLRYNRPYSCYAPIMETPWLKSFAQHSRFAEAFRSISQGQKDKSKFLAE TH_4621|M.thermoresistible__bu GVP---------------------AQQG---------VDGEVVRHRTLSS Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_01229|M.leprae_Br4923 LKVLPRDEWPSMIRRLVSEQIS--LLLRRTIDPDRLLSDYGLDSLGNLEL TH_4621|M.thermoresistible__bu VRSGRSSRWTAPGSRCGSGRRYGGESCRRTTGP----------AAGAAAR Mb1947c|M.bovis_AF2122/97 ------------------------------------------- Rv1912c|M.tuberculosis_H37Rv ------------------------------------------- MMAR_2814|M.marinum_M ------------------------------------------- MUL_2935|M.ulcerans_Agy99 ------------------------------------------- MAV_0242|M.avium_104 ------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 ------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK ------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 ------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 ------------------------------------------- MLBr_01229|M.leprae_Br4923 RTRIETETGIRISPTKITTIRSLAEHLCEELAATEAESAVTAT TH_4621|M.thermoresistible__bu RGRTRRRRRPRRPPPPPDRVR---------HRAGPAHGPVRR-