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RAVVITKHGDPSVLQVQQRPDPPPPGPGQLRIAVRAAGVNFADHLARVGLYPDAPKLPAVVGYEVAGTVE AAGAGVDESRIGERVLAGTRFGGYSEIVNVTATDSVVLPEGLSFEQGAAVPVNYATAWAALHGYGSLRAG ERVLVHAAAGGVGIAAVQFAKAAGAQVHGTASPGKHQRLAELGVDRAIDYRRDGWWKGLDSYDLVLDALG DTYLRRSYELLRPGGRLVGYGVSNMQEGEKRSLRRVAPHALSMLRGFNLMKQLEESKTVIGLNMLRLWDD RGTLEPWIAPLSEALGQGTAAPIVHAAIPFAEAPEAHRILAARENIGKVVLVP*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. ulcerans Agy99 | MUL_2935 | fadB5 | - | 100% (334) | oxidoreductase FadB5 |
M. ulcerans Agy99 | MUL_4387 | - | 7e-35 | 34.41% (340) | quinone oxidoreductase |
M. ulcerans Agy99 | MUL_2010 | mas | 1e-34 | 30.50% (318) | multifunctional mycocerosic acid synthase membrane-associated |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1947c | fadB5 | 1e-173 | 88.92% (334) | oxidoreductase FADB5 |
M. gilvum PYR-GCK | Mflv_1189 | - | 6e-42 | 35.63% (334) | alcohol dehydrogenase |
M. tuberculosis H37Rv | Rv1912c | fadB5 | 1e-173 | 88.62% (334) | oxidoreductase FADB5 |
M. leprae Br4923 | MLBr_00118 | - | 3e-35 | 32.18% (317) | putative oxidireductase |
M. abscessus ATCC 19977 | MAB_1112c | - | 4e-45 | 35.48% (341) | putative quinone oxidoreductase |
M. marinum M | MMAR_2814 | fadB5 | 0.0 | 97.60% (334) | oxidoreductase FadB5 |
M. avium 104 | MAV_0242 | - | 1e-36 | 33.95% (324) | quinone oxidoreductase |
M. smegmatis MC2 155 | MSMEG_6362 | - | 2e-38 | 35.11% (319) | quinone oxidoreductase |
M. thermoresistible (build 8) | TH_4621 | - | 4e-39 | 34.66% (326) | PUTATIVE mycocerosic acid synthase |
M. vanbaalenii PYR-1 | Mvan_5615 | - | 3e-38 | 36.08% (316) | alcohol dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu VNIVGDTPVNAVAVIGMACRLPGGIDSPQRLWEALLRGDDMVTEIPVDRW MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu DADDYFDPEPGVPGRTVSRWGAFLDDVAGFDPEFFGISEREAISIDPQQR MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu LLLETSWEAMEHAGLTPADVEGSSTGVFVGLSHDDYALLTSDAGALEEAY MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu GFTGSAFSMASGRIAYRLGVHGPAVTVDTACSSSLLAVHMACRSLQVGES MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu DLALAGGAMVMLEPRKYTSASGLGMLSPTGRCHAFDVAADGFVRSEGSVM MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu LLLKRLPDALRDNDRILAVVRGTAANQDGRTENISTPSIQAQADVYRSAL MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu AVAGVDPATVGMVEAHGTGTPVGDPIEYNSLTQVYGKTGPCALTSVKTNF MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu GHAESAAGALGMMKAILALQHGVVPQNLHFTRLPDEMAAIETNLFVPQAT MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu TLWPVREGCPRRAAVSSYGMSGTNVHAVLEQAPEPVQRPEESADTDAAGP MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu LVFALSSTSAEELRRTAGRLAEWVEAHTDEVVPADLAYTLARRRAHRPVR MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu TTVIADGVEALTAGLREVADGDAPYQPAVGMDDKAPVWVFSGQGSQWAGM MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu GAELLATEQVFAAKIAEIEPLVARESGFSVTEAMTASETVTGIDRVQPTL MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu FAIQVALAATMQSYGVRPGAVIGHSLGEVAAAVVAGALSLEDGVKVICRR MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu SRLCLRLAGAGAMAAIELPAQAVREFLAARGVDDVVLSVIASPESTVIGG MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu ATDTVRELVAAWEAQGVMAREVAVDVASHSPQVDPILDELEEILADLQPM MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu TPTVPYYSATSYDPREKPVCDADYWVDNLRHEVRFAAAVQAALEDGFRVF MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu GELSPHPLLTRAVEQTARGLDMPVAALPAMRREQEMPHGVRTMVGDLFAA MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu GAAVDFAALYPSGRLVDAPLPTWTRRKLVLSRENGEQQTRGGCTITVHPL MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu LGTHVRLPEEPERHVWQADLGTGAQPWLADHQIHTVAALPGAAYCEMALA MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu AAREVIDSDGVEVRDVRFEQMLLLDEQTEVSAVASAVEPGTLEFAVETAK MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu DGEHERRATAVLGAADDTEPPQAHDIDALLAEHPTRIEGDELRQWFDQRG MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu VQFGPAFTGLTAARIPEGTVTSVLAEVGLPGQIRSQQAPYGIHPALLDAC MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu FQSVAAHPDVQGAGSGLLLPLGVRRLQAFGPTRGARYCYARVTDADGSKA MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu EADLDVLDEHGNVLLRVQGLLMGGAAADGDDRDRVLGERLLTIEWQRRDL MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu PEADSAAGKWLLVSTSATADVSATRLSDALKQAGAESTSMCWPQQADHAD MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu NVDRFRAGIADGVTGVVVLTGPKNGNPDDAAARRGSDYVRHLVRITRELA MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu EIDGDAPRLFVVTRGAQAVLPQDRPNLEQAGLRGLLRVIGAEHPHLRTTQ MUL_2935|M.ulcerans_Agy99 ----------MRAVVITKHGDPSVLQVQQ--------------------- MMAR_2814|M.marinum_M ----------MRAVVITRHGDPSVLQVQQ--------------------- Mb1947c|M.bovis_AF2122/97 ----------MRAVVITKHGDPSVLQVRQ--------------------- Rv1912c|M.tuberculosis_H37Rv ----------MRAVVITKHGDPSVLQVRQ--------------------- MLBr_00118|M.leprae_Br4923 ----------MHAIVAE---SANQMVWRE--------------------- MAV_0242|M.avium_104 -------MATMRAIVAE---SADQLSWQE--------------------- MSMEG_6362|M.smegmatis_MC2_155 ----------MHAIVAS---VNGGLNWEN--------------------- Mflv_1189|M.gilvum_PYR-GCK --------------MAE---TPDQLNWQS--------------------- Mvan_5615|M.vanbaalenii_PYR-1 ---------MHAIVAQP---SSEGLTWQS--------------------- MAB_1112c|M.abscessus_ATCC_199 ----------MYAITLNGFGDPEVMQWTQ--------------------- TH_4621|M.thermoresistible__bu IDIADDADLDRVAVQLLGGGAEDETAWRDGQWYTARLSLSPLRPEERKQA . MUL_2935|M.ulcerans_Agy99 -------------------------RPDPPPPGPGQLRIAVRAAGVNFAD MMAR_2814|M.marinum_M -------------------------RPDPPPPGPGQLRISVRAAGVNFAD Mb1947c|M.bovis_AF2122/97 -------------------------RPDPPPPGPGQLRVAVRAAGVNFAD Rv1912c|M.tuberculosis_H37Rv -------------------------RPDPPPPGPGQLRVAVRAAGVNFAD MLBr_00118|M.leprae_Br4923 -------------------------VPDVTA-GPGEVLIEVAASGVNRAD MAV_0242|M.avium_104 -------------------------VADVSA-GPGEVVVKVAAAGVNRAD MSMEG_6362|M.smegmatis_MC2_155 -------------------------VASIAP-ANGEVLIKVHTAGINRAD Mflv_1189|M.gilvum_PYR-GCK -------------------------VPDPTP-GPGEVLIRVHAAGVNRAD Mvan_5615|M.vanbaalenii_PYR-1 -------------------------VPDIAP-APGEVLIRVAAAGVNRAD MAB_1112c|M.abscessus_ATCC_199 -------------------------VADLPAPGPGEVTIDVVAAGVNRAD TH_4621|M.thermoresistible__bu VVDCERDGMRLEIRTPGDLETMELAAFDRVPPGPGQIEVAVTASSINFAD . . . *:: : * ::.:* ** MUL_2935|M.ulcerans_Agy99 HLARVGLYPDAPKLPAVVGYEVAGTVEAAGAGVDESRIGERVLAGTRFGG MMAR_2814|M.marinum_M HLARVGLYPDAPKLPAVVGYEVAGTVEAVGAGVDESRIGERVLAGTRFGG Mb1947c|M.bovis_AF2122/97 HLARVGLYPDAPKLPAVVGYEVAGTVEAVGDGVDPNRVGERVLAGTRFGG Rv1912c|M.tuberculosis_H37Rv HLARVGLYPDAPKLPAVVGYEVAGTVEAVGDGVDPNRVGERVLAGTRFGG MLBr_00118|M.leprae_Br4923 VLQVAGKYPHPPGASAIIGMEVAGVVAAVSSGVTEWSVGQEVCALLAGGG MAV_0242|M.avium_104 VLQAAGKYPPPPGASETIGMEVSGVIAEVGDGVTEWSVGQEVCALLAGGG MSMEG_6362|M.smegmatis_MC2_155 LLQAAGKYPPPPGASEVIGLEVSGTVEALGDGVSGWSVGQPVCALLAGGG Mflv_1189|M.gilvum_PYR-GCK LLQAAGKYPPPPGASEIIGLEASGTIAAVGDGVTEWSEGQRVCALLAGGG Mvan_5615|M.vanbaalenii_PYR-1 LLQAAGKYPPPPGASDILGLEVSGTIAAIGEGVTKWSQGQPVCALLAGGG MAB_1112c|M.abscessus_ATCC_199 VMQRLGLYPPPPGVSEIPGLEVSGHIAEVGPAVQGWVPGDAVCALMAGGG TH_4621|M.thermoresistible__bu VLIAFGRYPTFDGRRPQLGTDFAGVVTAVGPDVTSHRVGDRVGGLSPNGC : * ** * : :* : . * *: * . * MUL_2935|M.ulcerans_Agy99 YSEIVNVTATDSVVLPEGLSFEQGAAVPVNYATAWAALHGYGSLRAGERV MMAR_2814|M.marinum_M YSEIVNVTATDAVVLPEGLSFEQGAAVPVNYATAWAALHGYGSLRAGERV Mb1947c|M.bovis_AF2122/97 YCEIVNVAATDSVVLPDALSFEQGAAVPVNYATAWAALHGYGSLRAGERV Rv1912c|M.tuberculosis_H37Rv YCEIVNVAATDSVVLPDALSFEQGAAVPVNYATAWAALHGYGSLRAGERV MLBr_00118|M.leprae_Br4923 YAEYVAVPASQVMPIPKGVNVVDSAGIPEVACTVWSNLVMAAHLSAGQLL MAV_0242|M.avium_104 YAEYVAVPAGQLLPIPAGVDLVDAAGLPEVACTVWSNLVLIAGLRNGQLL MSMEG_6362|M.smegmatis_MC2_155 YAEYVAVPAPQVLPVPDGVSLRDAAGLPEVACTVWSNVVMTAGLTAGHLL Mflv_1189|M.gilvum_PYR-GCK YAEYVAVPAGQVLPVPDGVPLDHAAGLPEVACTVWSNLVMTARLRAPELL Mvan_5615|M.vanbaalenii_PYR-1 YAEFVAVPAGQVLPIPDGVPVPHAAGLPEVACTVWSNVVMAAGLTAPELL MAB_1112c|M.abscessus_ATCC_199 YAERVNVAATQVLPVPRGVSITAAAALPETAATVWSNVVMTGGLRSGQTL TH_4621|M.thermoresistible__bu WSTFVTCDADLAVPLPDGLTEGQAAAVSTAHATAWYGLHDLARLGAGEKV :. * * : :* .: .*.:. .*.* : . * . : MUL_2935|M.ulcerans_Agy99 LVHAAAGGVGIAAVQFAKAAGAQVHGTASPG-KHQRLAELGVDRAIDYRR MMAR_2814|M.marinum_M LVHAAAGGVGIAAVQFAKAAGAQVHGTASPG-KHQRLAELGVDRAIDYRR Mb1947c|M.bovis_AF2122/97 LIHAAAGGVGIAAVQFAKAAKAEVHGTASPQ-KHQKLAEFGVDRAIDYRR Rv1912c|M.tuberculosis_H37Rv LIHAAAGGVGIAAVQFAKAAKAEVHGTASPQ-KHQKLAEFGVDRAIDYRR MLBr_00118|M.leprae_Br4923 LLHGGTSGIGSHGIQVARALGAKVAVTAGSEEKLEFCRALGAQITINYRD MAV_0242|M.avium_104 LVHGGASGIGSHAIQVARALGARVAVTAGSAEKLGFCRELGADITINYRD MSMEG_6362|M.smegmatis_MC2_155 LVHGGASGIGTHAIQVAKAMGARVAVTAGSEEKLGICRDLGADITINYRE Mflv_1189|M.gilvum_PYR-GCK LIHGGASGIGTHAIQVARALNCRVAVTAGSRNKLDLCAELGAEITIDYHH Mvan_5615|M.vanbaalenii_PYR-1 LVHGGASGIGTHAIQVAKALNCRVAVTAGSRNKLDLCAELGADITIDYHN MAB_1112c|M.abscessus_ATCC_199 LIHGGGSGIGTHAIQVGRALGANVAVTAGTQFKLDRCRELGAHTLINYRE TH_4621|M.thermoresistible__bu LIHSATGGVGLAAIAIARSVGAQIYATAGSPARRDLLRDMGIEHVYDSRS *:*.. .*:* .: ..:: ..: **.. : :* . : : MUL_2935|M.ulcerans_Agy99 DGWWKGLD-------SYDLVLDALGDTYLRRSYELLRPGGRLVGYGVSNM MMAR_2814|M.marinum_M DGWWKGLD-------SYDLVLDALGGTSLRRSYELLRPGGRLVGYGVSNM Mb1947c|M.bovis_AF2122/97 DGWWQGLG-------PYDVVLDALGGTSLRRSYTLLRPGGRLVGYGISNM Rv1912c|M.tuberculosis_H37Rv DGWWQGLG-------PYDVVLDALGGTSLRRSYTLLRPGGRLVGYGISNM MLBr_00118|M.leprae_Br4923 EDFVARLQQQNG---GADVILDIMGAAYLDRNIDALAIDGQLIVIGLQGG MAV_0242|M.avium_104 EDFVARLADETG---GADVILDIMGAAYLDRNIDALATDGQLVIIGMQGG MSMEG_6362|M.smegmatis_MC2_155 EDFVERLRRETD---GADVILDIMGAAYLDRNVDALATGGRLVIIGMQGG Mflv_1189|M.gilvum_PYR-GCK EDFVEVLRGADSDHPGADVILDIMGASYLDRNIDALATGGRLVIIGMQGG Mvan_5615|M.vanbaalenii_PYR-1 EDYVGVVRDAG----GADVILDIMGAAYLDRNIETLADGGRLVIIGMQGG MAB_1112c|M.abscessus_ATCC_199 QDFPAVVNAAYS---GANVILDIVGGGYLAKNVEALAENGHLTIIGLQGG TH_4621|M.thermoresistible__bu TAFADEIRRDTDG-YGVDVVLNSLPGAAQRAGLELLSFGGRFIEIGKR-D : : :::*: : . * .*:: * MUL_2935|M.ulcerans_Agy99 QEGEKRSLRRVAPHALSMLRGFNLMKQLEESKTVIGLNMLRLWDDRGTLE MMAR_2814|M.marinum_M QEGEKRSLRRVAPHALSMLRGFNLMKQLEESKTVIGLNMLRLWDDRGTLE Mb1947c|M.bovis_AF2122/97 QHGEKRSMRRVAPHALSMLRGFNLMKQLEESKTVIGLNMLRLWDDRRTLE Rv1912c|M.tuberculosis_H37Rv QHGEKRSMRRVAPHALSMLRGFNLMKQLEESKTVIGLNMLRLWDDRRTLE MLBr_00118|M.leprae_Br4923 VKGELNLGKVLSKRAR-------IIGSTLRARPVNGPNSK-----SEIVA MAV_0242|M.avium_104 VKAELNIGKLLAKRAR-------VIGTTLRGRPVSGPNSK-----TEIVQ MSMEG_6362|M.smegmatis_MC2_155 VKAELNIGKLLGKRAG-------VIATSLRPRPVDGPGGK-----GEIVR Mflv_1189|M.gilvum_PYR-GCK TKAEINLGKLLAKRGS-------VMATALRSRPVTGRGSK-----SVIVS Mvan_5615|M.vanbaalenii_PYR-1 AKAELNIGKLLTKRGS-------VIATALRSRPVHGRGGK-----ADIVA MAB_1112c|M.abscessus_ATCC_199 AAAELNLGALLFKRGS-------VHATNLRRRPEQGPGSK-----AEIIA TH_4621|M.thermoresistible__bu IYGDTRLGLFPFRRNL------AFHGVDLGLMADSHPHK---------IR .: . : . . : MUL_2935|M.ulcerans_Agy99 PWIAPLSEALGQGTAAPIVHAAIPFAEAPEAHRILAARENIGKVVLVP-- MMAR_2814|M.marinum_M PWIAPLSEALDQGTAAPIVHAAIPFGEAPEAHRILAARENIGKVVLVP-- Mb1947c|M.bovis_AF2122/97 PWIAPLTKALNDGTILPIVHAIVPFAEAPEAHRILAARENVGKVVLVP-- Rv1912c|M.tuberculosis_H37Rv PWIAPLTKALNDGTILPIVHAIVPFAEAPEAHRILAARENVDKVVLVP-- MLBr_00118|M.leprae_Br4923 AVTASIWPMIADGSVRPIIGARMAVQQAADAHQLLLSGKVSGKIVLTVAG MAV_0242|M.avium_104 AVTASVWPMIADGRVRPIIGARLPIQQAGDAHRRLVASEVTGKIVLTV-- MSMEG_6362|M.smegmatis_MC2_155 AVRENVWPMIADGRVKPIIGAELPIENAQQGHDLLASGKVTGKVLLRVSE Mflv_1189|M.gilvum_PYR-GCK EVIENVWPLVADGQVRPVIGAEFPISEAQAAHELLASGDVSGKVILRVDV Mvan_5615|M.vanbaalenii_PYR-1 RVGAELWPLVADGQVRPVIGAEFPIAEAQAAHELLASGDVSGKVLLRVDV MAB_1112c|M.abscessus_ATCC_199 ELRQHLWPLIAEGTVAPVVSAEVPVTDAAEAHRLLDSPETVGKVLLTVRR TH_4621|M.thermoresistible__bu ELLETVYRLTADGVLPMPQSTHYPLAEAATAIRVMSAAEHVGKLVLDVPH : :* : .. :* . : : . .*::* MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 SGTETLLSRHH--------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 Q------------------------------------------------- TH_4621|M.thermoresistible__bu TGRADVVVPPEQASPFRSDGAYIVTGGMGGLGLYLAGEMAAAGAGCIVLN MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu GRSAPSGEALRTIEQLRAAGTEVIVECGXXXRGQPVEVAVPTELRHADEH MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu PDRRGAQLCDEFARGEQGAQRNQHRTDAGEGQRDAHPPGAVGHDQPDPGA MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu LSDTGLDERGGQFPGVGVQIPVADPGVGIDHRGAVRVDSGVPAQQGVDGE MUL_2935|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2814|M.marinum_M -------------------------------------------------- Mb1947c|M.bovis_AF2122/97 -------------------------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------------------------- MAV_0242|M.avium_104 -------------------------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu VVRHRTLSSVRSGRSSRWTAPGSRCGSGRRYGGESCRRTTGPAAGAAARR MUL_2935|M.ulcerans_Agy99 -------------------------------- MMAR_2814|M.marinum_M -------------------------------- Mb1947c|M.bovis_AF2122/97 -------------------------------- Rv1912c|M.tuberculosis_H37Rv -------------------------------- MLBr_00118|M.leprae_Br4923 -------------------------------- MAV_0242|M.avium_104 -------------------------------- MSMEG_6362|M.smegmatis_MC2_155 -------------------------------- Mflv_1189|M.gilvum_PYR-GCK -------------------------------- Mvan_5615|M.vanbaalenii_PYR-1 -------------------------------- MAB_1112c|M.abscessus_ATCC_199 -------------------------------- TH_4621|M.thermoresistible__bu GRTRRRRRPRRPPPPPDRVRHRAGPAHGPVRR