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M. ulcerans Agy99 MUL_2935 (fadB5)

annotation: oxidoreductase FadB5
coordinates: 3258655 - 3259659
length: 334

RAVVITKHGDPSVLQVQQRPDPPPPGPGQLRIAVRAAGVNFADHLARVGLYPDAPKLPAVVGYEVAGTVE
AAGAGVDESRIGERVLAGTRFGGYSEIVNVTATDSVVLPEGLSFEQGAAVPVNYATAWAALHGYGSLRAG
ERVLVHAAAGGVGIAAVQFAKAAGAQVHGTASPGKHQRLAELGVDRAIDYRRDGWWKGLDSYDLVLDALG
DTYLRRSYELLRPGGRLVGYGVSNMQEGEKRSLRRVAPHALSMLRGFNLMKQLEESKTVIGLNMLRLWDD
RGTLEPWIAPLSEALGQGTAAPIVHAAIPFAEAPEAHRILAARENIGKVVLVP*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_2935fadB5-100% (334)oxidoreductase FadB5
M. ulcerans Agy99MUL_4387-7e-3534.41% (340) quinone oxidoreductase
M. ulcerans Agy99MUL_2010mas1e-3430.50% (318) multifunctional mycocerosic acid synthase membrane-associated

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1947cfadB51e-17388.92% (334) oxidoreductase FADB5
M. gilvum PYR-GCKMflv_1189-6e-4235.63% (334) alcohol dehydrogenase
M. tuberculosis H37RvRv1912cfadB51e-17388.62% (334) oxidoreductase FADB5
M. leprae Br4923MLBr_00118-3e-3532.18% (317) putative oxidireductase
M. abscessus ATCC 19977MAB_1112c-4e-4535.48% (341) putative quinone oxidoreductase
M. marinum MMMAR_2814fadB50.097.60% (334) oxidoreductase FadB5
M. avium 104MAV_0242-1e-3633.95% (324) quinone oxidoreductase
M. smegmatis MC2 155MSMEG_6362-2e-3835.11% (319) quinone oxidoreductase
M. thermoresistible (build 8)TH_4621-4e-3934.66% (326) PUTATIVE mycocerosic acid synthase
M. vanbaalenii PYR-1Mvan_5615-3e-3836.08% (316) alcohol dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2814|M.marinum_M               --------------------------------------------------
Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
MAV_0242|M.avium_104                --------------------------------------------------
MSMEG_6362|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1189|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5615|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1112c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      VNIVGDTPVNAVAVIGMACRLPGGIDSPQRLWEALLRGDDMVTEIPVDRW
                                                                                      

MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2814|M.marinum_M               --------------------------------------------------
Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
MAV_0242|M.avium_104                --------------------------------------------------
MSMEG_6362|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1189|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5615|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1112c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      DADDYFDPEPGVPGRTVSRWGAFLDDVAGFDPEFFGISEREAISIDPQQR
                                                                                      

MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2814|M.marinum_M               --------------------------------------------------
Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
MAV_0242|M.avium_104                --------------------------------------------------
MSMEG_6362|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1189|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5615|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1112c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      LLLETSWEAMEHAGLTPADVEGSSTGVFVGLSHDDYALLTSDAGALEEAY
                                                                                      

MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2814|M.marinum_M               --------------------------------------------------
Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
MAV_0242|M.avium_104                --------------------------------------------------
MSMEG_6362|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1189|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5615|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1112c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      GFTGSAFSMASGRIAYRLGVHGPAVTVDTACSSSLLAVHMACRSLQVGES
                                                                                      

MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2814|M.marinum_M               --------------------------------------------------
Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
MAV_0242|M.avium_104                --------------------------------------------------
MSMEG_6362|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1189|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5615|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1112c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      DLALAGGAMVMLEPRKYTSASGLGMLSPTGRCHAFDVAADGFVRSEGSVM
                                                                                      

MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2814|M.marinum_M               --------------------------------------------------
Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
MAV_0242|M.avium_104                --------------------------------------------------
MSMEG_6362|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1189|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5615|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1112c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      LLLKRLPDALRDNDRILAVVRGTAANQDGRTENISTPSIQAQADVYRSAL
                                                                                      

MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2814|M.marinum_M               --------------------------------------------------
Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
MAV_0242|M.avium_104                --------------------------------------------------
MSMEG_6362|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1189|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5615|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1112c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      AVAGVDPATVGMVEAHGTGTPVGDPIEYNSLTQVYGKTGPCALTSVKTNF
                                                                                      

MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2814|M.marinum_M               --------------------------------------------------
Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
MAV_0242|M.avium_104                --------------------------------------------------
MSMEG_6362|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1189|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5615|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1112c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      GHAESAAGALGMMKAILALQHGVVPQNLHFTRLPDEMAAIETNLFVPQAT
                                                                                      

MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2814|M.marinum_M               --------------------------------------------------
Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
MAV_0242|M.avium_104                --------------------------------------------------
MSMEG_6362|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1189|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5615|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1112c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      TLWPVREGCPRRAAVSSYGMSGTNVHAVLEQAPEPVQRPEESADTDAAGP
                                                                                      

MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2814|M.marinum_M               --------------------------------------------------
Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
MAV_0242|M.avium_104                --------------------------------------------------
MSMEG_6362|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1189|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5615|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1112c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      LVFALSSTSAEELRRTAGRLAEWVEAHTDEVVPADLAYTLARRRAHRPVR
                                                                                      

MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2814|M.marinum_M               --------------------------------------------------
Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
MAV_0242|M.avium_104                --------------------------------------------------
MSMEG_6362|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1189|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5615|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1112c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      TTVIADGVEALTAGLREVADGDAPYQPAVGMDDKAPVWVFSGQGSQWAGM
                                                                                      

MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2814|M.marinum_M               --------------------------------------------------
Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
MAV_0242|M.avium_104                --------------------------------------------------
MSMEG_6362|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1189|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5615|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1112c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      GAELLATEQVFAAKIAEIEPLVARESGFSVTEAMTASETVTGIDRVQPTL
                                                                                      

MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2814|M.marinum_M               --------------------------------------------------
Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
MAV_0242|M.avium_104                --------------------------------------------------
MSMEG_6362|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1189|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5615|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1112c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      FAIQVALAATMQSYGVRPGAVIGHSLGEVAAAVVAGALSLEDGVKVICRR
                                                                                      

MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2814|M.marinum_M               --------------------------------------------------
Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
MAV_0242|M.avium_104                --------------------------------------------------
MSMEG_6362|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1189|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5615|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1112c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      SRLCLRLAGAGAMAAIELPAQAVREFLAARGVDDVVLSVIASPESTVIGG
                                                                                      

MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2814|M.marinum_M               --------------------------------------------------
Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
MAV_0242|M.avium_104                --------------------------------------------------
MSMEG_6362|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1189|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5615|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1112c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      ATDTVRELVAAWEAQGVMAREVAVDVASHSPQVDPILDELEEILADLQPM
                                                                                      

MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2814|M.marinum_M               --------------------------------------------------
Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
MAV_0242|M.avium_104                --------------------------------------------------
MSMEG_6362|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1189|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5615|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1112c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      TPTVPYYSATSYDPREKPVCDADYWVDNLRHEVRFAAAVQAALEDGFRVF
                                                                                      

MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2814|M.marinum_M               --------------------------------------------------
Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
MAV_0242|M.avium_104                --------------------------------------------------
MSMEG_6362|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1189|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5615|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1112c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      GELSPHPLLTRAVEQTARGLDMPVAALPAMRREQEMPHGVRTMVGDLFAA
                                                                                      

MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2814|M.marinum_M               --------------------------------------------------
Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
MAV_0242|M.avium_104                --------------------------------------------------
MSMEG_6362|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1189|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5615|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1112c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      GAAVDFAALYPSGRLVDAPLPTWTRRKLVLSRENGEQQTRGGCTITVHPL
                                                                                      

MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2814|M.marinum_M               --------------------------------------------------
Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
MAV_0242|M.avium_104                --------------------------------------------------
MSMEG_6362|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1189|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5615|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1112c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      LGTHVRLPEEPERHVWQADLGTGAQPWLADHQIHTVAALPGAAYCEMALA
                                                                                      

MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2814|M.marinum_M               --------------------------------------------------
Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
MAV_0242|M.avium_104                --------------------------------------------------
MSMEG_6362|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1189|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5615|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1112c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      AAREVIDSDGVEVRDVRFEQMLLLDEQTEVSAVASAVEPGTLEFAVETAK
                                                                                      

MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2814|M.marinum_M               --------------------------------------------------
Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
MAV_0242|M.avium_104                --------------------------------------------------
MSMEG_6362|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1189|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5615|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1112c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      DGEHERRATAVLGAADDTEPPQAHDIDALLAEHPTRIEGDELRQWFDQRG
                                                                                      

MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2814|M.marinum_M               --------------------------------------------------
Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
MAV_0242|M.avium_104                --------------------------------------------------
MSMEG_6362|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1189|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5615|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1112c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      VQFGPAFTGLTAARIPEGTVTSVLAEVGLPGQIRSQQAPYGIHPALLDAC
                                                                                      

MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2814|M.marinum_M               --------------------------------------------------
Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
MAV_0242|M.avium_104                --------------------------------------------------
MSMEG_6362|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1189|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5615|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1112c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      FQSVAAHPDVQGAGSGLLLPLGVRRLQAFGPTRGARYCYARVTDADGSKA
                                                                                      

MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2814|M.marinum_M               --------------------------------------------------
Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
MAV_0242|M.avium_104                --------------------------------------------------
MSMEG_6362|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1189|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5615|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1112c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      EADLDVLDEHGNVLLRVQGLLMGGAAADGDDRDRVLGERLLTIEWQRRDL
                                                                                      

MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2814|M.marinum_M               --------------------------------------------------
Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
MAV_0242|M.avium_104                --------------------------------------------------
MSMEG_6362|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1189|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5615|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1112c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      PEADSAAGKWLLVSTSATADVSATRLSDALKQAGAESTSMCWPQQADHAD
                                                                                      

MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2814|M.marinum_M               --------------------------------------------------
Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
MAV_0242|M.avium_104                --------------------------------------------------
MSMEG_6362|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1189|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5615|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1112c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      NVDRFRAGIADGVTGVVVLTGPKNGNPDDAAARRGSDYVRHLVRITRELA
                                                                                      

MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2814|M.marinum_M               --------------------------------------------------
Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
MAV_0242|M.avium_104                --------------------------------------------------
MSMEG_6362|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1189|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5615|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1112c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      EIDGDAPRLFVVTRGAQAVLPQDRPNLEQAGLRGLLRVIGAEHPHLRTTQ
                                                                                      

MUL_2935|M.ulcerans_Agy99           ----------MRAVVITKHGDPSVLQVQQ---------------------
MMAR_2814|M.marinum_M               ----------MRAVVITRHGDPSVLQVQQ---------------------
Mb1947c|M.bovis_AF2122/97           ----------MRAVVITKHGDPSVLQVRQ---------------------
Rv1912c|M.tuberculosis_H37Rv        ----------MRAVVITKHGDPSVLQVRQ---------------------
MLBr_00118|M.leprae_Br4923          ----------MHAIVAE---SANQMVWRE---------------------
MAV_0242|M.avium_104                -------MATMRAIVAE---SADQLSWQE---------------------
MSMEG_6362|M.smegmatis_MC2_155      ----------MHAIVAS---VNGGLNWEN---------------------
Mflv_1189|M.gilvum_PYR-GCK          --------------MAE---TPDQLNWQS---------------------
Mvan_5615|M.vanbaalenii_PYR-1       ---------MHAIVAQP---SSEGLTWQS---------------------
MAB_1112c|M.abscessus_ATCC_199      ----------MYAITLNGFGDPEVMQWTQ---------------------
TH_4621|M.thermoresistible__bu      IDIADDADLDRVAVQLLGGGAEDETAWRDGQWYTARLSLSPLRPEERKQA
                                                                .                     

MUL_2935|M.ulcerans_Agy99           -------------------------RPDPPPPGPGQLRIAVRAAGVNFAD
MMAR_2814|M.marinum_M               -------------------------RPDPPPPGPGQLRISVRAAGVNFAD
Mb1947c|M.bovis_AF2122/97           -------------------------RPDPPPPGPGQLRVAVRAAGVNFAD
Rv1912c|M.tuberculosis_H37Rv        -------------------------RPDPPPPGPGQLRVAVRAAGVNFAD
MLBr_00118|M.leprae_Br4923          -------------------------VPDVTA-GPGEVLIEVAASGVNRAD
MAV_0242|M.avium_104                -------------------------VADVSA-GPGEVVVKVAAAGVNRAD
MSMEG_6362|M.smegmatis_MC2_155      -------------------------VASIAP-ANGEVLIKVHTAGINRAD
Mflv_1189|M.gilvum_PYR-GCK          -------------------------VPDPTP-GPGEVLIRVHAAGVNRAD
Mvan_5615|M.vanbaalenii_PYR-1       -------------------------VPDIAP-APGEVLIRVAAAGVNRAD
MAB_1112c|M.abscessus_ATCC_199      -------------------------VADLPAPGPGEVTIDVVAAGVNRAD
TH_4621|M.thermoresistible__bu      VVDCERDGMRLEIRTPGDLETMELAAFDRVPPGPGQIEVAVTASSINFAD
                                                               .  . . *:: : * ::.:* **

MUL_2935|M.ulcerans_Agy99           HLARVGLYPDAPKLPAVVGYEVAGTVEAAGAGVDESRIGERVLAGTRFGG
MMAR_2814|M.marinum_M               HLARVGLYPDAPKLPAVVGYEVAGTVEAVGAGVDESRIGERVLAGTRFGG
Mb1947c|M.bovis_AF2122/97           HLARVGLYPDAPKLPAVVGYEVAGTVEAVGDGVDPNRVGERVLAGTRFGG
Rv1912c|M.tuberculosis_H37Rv        HLARVGLYPDAPKLPAVVGYEVAGTVEAVGDGVDPNRVGERVLAGTRFGG
MLBr_00118|M.leprae_Br4923          VLQVAGKYPHPPGASAIIGMEVAGVVAAVSSGVTEWSVGQEVCALLAGGG
MAV_0242|M.avium_104                VLQAAGKYPPPPGASETIGMEVSGVIAEVGDGVTEWSVGQEVCALLAGGG
MSMEG_6362|M.smegmatis_MC2_155      LLQAAGKYPPPPGASEVIGLEVSGTVEALGDGVSGWSVGQPVCALLAGGG
Mflv_1189|M.gilvum_PYR-GCK          LLQAAGKYPPPPGASEIIGLEASGTIAAVGDGVTEWSEGQRVCALLAGGG
Mvan_5615|M.vanbaalenii_PYR-1       LLQAAGKYPPPPGASDILGLEVSGTIAAIGEGVTKWSQGQPVCALLAGGG
MAB_1112c|M.abscessus_ATCC_199      VMQRLGLYPPPPGVSEIPGLEVSGHIAEVGPAVQGWVPGDAVCALMAGGG
TH_4621|M.thermoresistible__bu      VLIAFGRYPTFDGRRPQLGTDFAGVVTAVGPDVTSHRVGDRVGGLSPNGC
                                     :   * **         * : :* :   .  *     *: * .    * 

MUL_2935|M.ulcerans_Agy99           YSEIVNVTATDSVVLPEGLSFEQGAAVPVNYATAWAALHGYGSLRAGERV
MMAR_2814|M.marinum_M               YSEIVNVTATDAVVLPEGLSFEQGAAVPVNYATAWAALHGYGSLRAGERV
Mb1947c|M.bovis_AF2122/97           YCEIVNVAATDSVVLPDALSFEQGAAVPVNYATAWAALHGYGSLRAGERV
Rv1912c|M.tuberculosis_H37Rv        YCEIVNVAATDSVVLPDALSFEQGAAVPVNYATAWAALHGYGSLRAGERV
MLBr_00118|M.leprae_Br4923          YAEYVAVPASQVMPIPKGVNVVDSAGIPEVACTVWSNLVMAAHLSAGQLL
MAV_0242|M.avium_104                YAEYVAVPAGQLLPIPAGVDLVDAAGLPEVACTVWSNLVLIAGLRNGQLL
MSMEG_6362|M.smegmatis_MC2_155      YAEYVAVPAPQVLPVPDGVSLRDAAGLPEVACTVWSNVVMTAGLTAGHLL
Mflv_1189|M.gilvum_PYR-GCK          YAEYVAVPAGQVLPVPDGVPLDHAAGLPEVACTVWSNLVMTARLRAPELL
Mvan_5615|M.vanbaalenii_PYR-1       YAEFVAVPAGQVLPIPDGVPVPHAAGLPEVACTVWSNVVMAAGLTAPELL
MAB_1112c|M.abscessus_ATCC_199      YAERVNVAATQVLPVPRGVSITAAAALPETAATVWSNVVMTGGLRSGQTL
TH_4621|M.thermoresistible__bu      WSTFVTCDADLAVPLPDGLTEGQAAAVSTAHATAWYGLHDLARLGAGEKV
                                    :.  *   *   : :* .:    .*.:.   .*.*  :   . *   . :

MUL_2935|M.ulcerans_Agy99           LVHAAAGGVGIAAVQFAKAAGAQVHGTASPG-KHQRLAELGVDRAIDYRR
MMAR_2814|M.marinum_M               LVHAAAGGVGIAAVQFAKAAGAQVHGTASPG-KHQRLAELGVDRAIDYRR
Mb1947c|M.bovis_AF2122/97           LIHAAAGGVGIAAVQFAKAAKAEVHGTASPQ-KHQKLAEFGVDRAIDYRR
Rv1912c|M.tuberculosis_H37Rv        LIHAAAGGVGIAAVQFAKAAKAEVHGTASPQ-KHQKLAEFGVDRAIDYRR
MLBr_00118|M.leprae_Br4923          LLHGGTSGIGSHGIQVARALGAKVAVTAGSEEKLEFCRALGAQITINYRD
MAV_0242|M.avium_104                LVHGGASGIGSHAIQVARALGARVAVTAGSAEKLGFCRELGADITINYRD
MSMEG_6362|M.smegmatis_MC2_155      LVHGGASGIGTHAIQVAKAMGARVAVTAGSEEKLGICRDLGADITINYRE
Mflv_1189|M.gilvum_PYR-GCK          LIHGGASGIGTHAIQVARALNCRVAVTAGSRNKLDLCAELGAEITIDYHH
Mvan_5615|M.vanbaalenii_PYR-1       LVHGGASGIGTHAIQVAKALNCRVAVTAGSRNKLDLCAELGADITIDYHN
MAB_1112c|M.abscessus_ATCC_199      LIHGGGSGIGTHAIQVGRALGANVAVTAGTQFKLDRCRELGAHTLINYRE
TH_4621|M.thermoresistible__bu      LIHSATGGVGLAAIAIARSVGAQIYATAGSPARRDLLRDMGIEHVYDSRS
                                    *:*.. .*:*  .: ..::  ..:  **..  :      :* .   : : 

MUL_2935|M.ulcerans_Agy99           DGWWKGLD-------SYDLVLDALGDTYLRRSYELLRPGGRLVGYGVSNM
MMAR_2814|M.marinum_M               DGWWKGLD-------SYDLVLDALGGTSLRRSYELLRPGGRLVGYGVSNM
Mb1947c|M.bovis_AF2122/97           DGWWQGLG-------PYDVVLDALGGTSLRRSYTLLRPGGRLVGYGISNM
Rv1912c|M.tuberculosis_H37Rv        DGWWQGLG-------PYDVVLDALGGTSLRRSYTLLRPGGRLVGYGISNM
MLBr_00118|M.leprae_Br4923          EDFVARLQQQNG---GADVILDIMGAAYLDRNIDALAIDGQLIVIGLQGG
MAV_0242|M.avium_104                EDFVARLADETG---GADVILDIMGAAYLDRNIDALATDGQLVIIGMQGG
MSMEG_6362|M.smegmatis_MC2_155      EDFVERLRRETD---GADVILDIMGAAYLDRNVDALATGGRLVIIGMQGG
Mflv_1189|M.gilvum_PYR-GCK          EDFVEVLRGADSDHPGADVILDIMGASYLDRNIDALATGGRLVIIGMQGG
Mvan_5615|M.vanbaalenii_PYR-1       EDYVGVVRDAG----GADVILDIMGAAYLDRNIETLADGGRLVIIGMQGG
MAB_1112c|M.abscessus_ATCC_199      QDFPAVVNAAYS---GANVILDIVGGGYLAKNVEALAENGHLTIIGLQGG
TH_4621|M.thermoresistible__bu      TAFADEIRRDTDG-YGVDVVLNSLPGAAQRAGLELLSFGGRFIEIGKR-D
                                      :   :          :::*: :       .   *  .*::   *    

MUL_2935|M.ulcerans_Agy99           QEGEKRSLRRVAPHALSMLRGFNLMKQLEESKTVIGLNMLRLWDDRGTLE
MMAR_2814|M.marinum_M               QEGEKRSLRRVAPHALSMLRGFNLMKQLEESKTVIGLNMLRLWDDRGTLE
Mb1947c|M.bovis_AF2122/97           QHGEKRSMRRVAPHALSMLRGFNLMKQLEESKTVIGLNMLRLWDDRRTLE
Rv1912c|M.tuberculosis_H37Rv        QHGEKRSMRRVAPHALSMLRGFNLMKQLEESKTVIGLNMLRLWDDRRTLE
MLBr_00118|M.leprae_Br4923          VKGELNLGKVLSKRAR-------IIGSTLRARPVNGPNSK-----SEIVA
MAV_0242|M.avium_104                VKAELNIGKLLAKRAR-------VIGTTLRGRPVSGPNSK-----TEIVQ
MSMEG_6362|M.smegmatis_MC2_155      VKAELNIGKLLGKRAG-------VIATSLRPRPVDGPGGK-----GEIVR
Mflv_1189|M.gilvum_PYR-GCK          TKAEINLGKLLAKRGS-------VMATALRSRPVTGRGSK-----SVIVS
Mvan_5615|M.vanbaalenii_PYR-1       AKAELNIGKLLTKRGS-------VIATALRSRPVHGRGGK-----ADIVA
MAB_1112c|M.abscessus_ATCC_199      AAAELNLGALLFKRGS-------VHATNLRRRPEQGPGSK-----AEIIA
TH_4621|M.thermoresistible__bu      IYGDTRLGLFPFRRNL------AFHGVDLGLMADSHPHK---------IR
                                      .: .       :         .        .               : 

MUL_2935|M.ulcerans_Agy99           PWIAPLSEALGQGTAAPIVHAAIPFAEAPEAHRILAARENIGKVVLVP--
MMAR_2814|M.marinum_M               PWIAPLSEALDQGTAAPIVHAAIPFGEAPEAHRILAARENIGKVVLVP--
Mb1947c|M.bovis_AF2122/97           PWIAPLTKALNDGTILPIVHAIVPFAEAPEAHRILAARENVGKVVLVP--
Rv1912c|M.tuberculosis_H37Rv        PWIAPLTKALNDGTILPIVHAIVPFAEAPEAHRILAARENVDKVVLVP--
MLBr_00118|M.leprae_Br4923          AVTASIWPMIADGSVRPIIGARMAVQQAADAHQLLLSGKVSGKIVLTVAG
MAV_0242|M.avium_104                AVTASVWPMIADGRVRPIIGARLPIQQAGDAHRRLVASEVTGKIVLTV--
MSMEG_6362|M.smegmatis_MC2_155      AVRENVWPMIADGRVKPIIGAELPIENAQQGHDLLASGKVTGKVLLRVSE
Mflv_1189|M.gilvum_PYR-GCK          EVIENVWPLVADGQVRPVIGAEFPISEAQAAHELLASGDVSGKVILRVDV
Mvan_5615|M.vanbaalenii_PYR-1       RVGAELWPLVADGQVRPVIGAEFPIAEAQAAHELLASGDVSGKVLLRVDV
MAB_1112c|M.abscessus_ATCC_199      ELRQHLWPLIAEGTVAPVVSAEVPVTDAAEAHRLLDSPETVGKVLLTVRR
TH_4621|M.thermoresistible__bu      ELLETVYRLTADGVLPMPQSTHYPLAEAATAIRVMSAAEHVGKLVLDVPH
                                         :     :*       :  .. :*  .   : : .  .*::*    

MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2814|M.marinum_M               --------------------------------------------------
Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00118|M.leprae_Br4923          SGTETLLSRHH---------------------------------------
MAV_0242|M.avium_104                --------------------------------------------------
MSMEG_6362|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1189|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5615|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1112c|M.abscessus_ATCC_199      Q-------------------------------------------------
TH_4621|M.thermoresistible__bu      TGRADVVVPPEQASPFRSDGAYIVTGGMGGLGLYLAGEMAAAGAGCIVLN
                                                                                      

MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2814|M.marinum_M               --------------------------------------------------
Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
MAV_0242|M.avium_104                --------------------------------------------------
MSMEG_6362|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1189|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5615|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1112c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      GRSAPSGEALRTIEQLRAAGTEVIVECGXXXRGQPVEVAVPTELRHADEH
                                                                                      

MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2814|M.marinum_M               --------------------------------------------------
Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
MAV_0242|M.avium_104                --------------------------------------------------
MSMEG_6362|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1189|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5615|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1112c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      PDRRGAQLCDEFARGEQGAQRNQHRTDAGEGQRDAHPPGAVGHDQPDPGA
                                                                                      

MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2814|M.marinum_M               --------------------------------------------------
Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
MAV_0242|M.avium_104                --------------------------------------------------
MSMEG_6362|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1189|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5615|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1112c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      LSDTGLDERGGQFPGVGVQIPVADPGVGIDHRGAVRVDSGVPAQQGVDGE
                                                                                      

MUL_2935|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2814|M.marinum_M               --------------------------------------------------
Mb1947c|M.bovis_AF2122/97           --------------------------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------------------------
MAV_0242|M.avium_104                --------------------------------------------------
MSMEG_6362|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1189|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5615|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1112c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      VVRHRTLSSVRSGRSSRWTAPGSRCGSGRRYGGESCRRTTGPAAGAAARR
                                                                                      

MUL_2935|M.ulcerans_Agy99           --------------------------------
MMAR_2814|M.marinum_M               --------------------------------
Mb1947c|M.bovis_AF2122/97           --------------------------------
Rv1912c|M.tuberculosis_H37Rv        --------------------------------
MLBr_00118|M.leprae_Br4923          --------------------------------
MAV_0242|M.avium_104                --------------------------------
MSMEG_6362|M.smegmatis_MC2_155      --------------------------------
Mflv_1189|M.gilvum_PYR-GCK          --------------------------------
Mvan_5615|M.vanbaalenii_PYR-1       --------------------------------
MAB_1112c|M.abscessus_ATCC_199      --------------------------------
TH_4621|M.thermoresistible__bu      GRTRRRRRPRRPPPPPDRVRHRAGPAHGPVRR