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VGQLSVEPDVIRADKRAARVARHIEAEIVRRGWTVGASLGSEGALQQRYGVSRSVLREAVRLVEHHQVAR MRRGPNGGLLICAPDAGPATRAVVIYLEYLGITLGELLDARLVFEPLAASLAAEHIDEAGIDRLRAVLRA EEQRKPGLPAVRDEFHVALARQSKNPVLQLFIEILMRLTRRYALTSRTDTVAEAFEAVDQMHNDHAAIAA AVTAGDSARAKTLSEQHVQQVTGWLQQHQPGGDAKLAHVPRRSLRLDSETPPGKLAEVLAATIADDIAAS GWQLDSVFGTETALLQRYRVSRAALREAVRLLEYHSVARMRRGPGGGLVVTKPQSQASIDTIALYLQYRQ PSREDLRCVRDAIEIANVAKVVEQRARPEVASVLDELVVASDFAFEDAADAARKVAVEEFGFHVGLAQLA GNALLDLFLRIIVELFQRHWSSTEHQQPTFNDVGAVEHAHQRIREAIIAGDDSLARYRIRRHLDAAASWW L
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1630 | - | - | 100% (491) | transcriptional regulatory protein |
| M. marinum M | MMAR_3975 | - | 1e-10 | 25.22% (226) | FadR family transcriptional regulator |
| M. marinum M | MMAR_0749 | - | 6e-10 | 25.00% (232) | GntR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3086c | - | 0.0 | 72.21% (493) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2114 | - | 9e-18 | 32.00% (175) | GntR domain-containing protein |
| M. tuberculosis H37Rv | Rv3060c | - | 0.0 | 72.21% (493) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2272c | - | 4e-10 | 24.48% (241) | putative transcriptional regulator, GntR |
| M. avium 104 | MAV_3932 | - | 0.0 | 71.93% (488) | transcriptional regulator, GntR family protein |
| M. smegmatis MC2 155 | MSMEG_5201 | - | 4e-15 | 26.52% (230) | regulatory protein GntR, HTH |
| M. thermoresistible (build 8) | TH_4408 | - | 3e-23 | 31.39% (223) | PUTATIVE regulatory protein GntR, HTH |
| M. ulcerans Agy99 | MUL_3832 | - | 3e-11 | 25.22% (226) | FadR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4590 | - | 2e-16 | 27.15% (221) | GntR domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3086c|M.bovis_AF2122/97 --------------MSTEPDAVWTDKRASKIARRIEADIVRRGWPIGASL
Rv3060c|M.tuberculosis_H37Rv --------------MSTEPDAVWTDKRASKIARRIEADIVRRGWPIGASL
MMAR_1630|M.marinum_M -----------MGQLSVEPDVIRADKRAARVARHIEAEIVRRGWTVGASL
MAV_3932|M.avium_104 --------------MNAEPRTGPAKTLASALARDIEAEIVRRGWAVGESL
Mflv_2114|M.gilvum_PYR-GCK MARSTPLAPMIGPDAVASRTAVRSPKTAELVAGTLRRMVVEGQLKDGDFL
Mvan_4590|M.vanbaalenii_PYR-1 MTRNTPLAPMIGPDAVASRAAVRSPKTAELVAGTLRRMVVEGQLKDGDFL
MSMEG_5201|M.smegmatis_MC2_155 MAGSTPLAPMIGPDAITPRAAVRSPKTAELVAGTLRRMVVEGQLKDGDFL
TH_4408|M.thermoresistible__bu ------------VEDYMEVTNLREPKMADRVATVLRRMFIRGEIPEGTML
MUL_3832|M.ulcerans_Agy99 -----MTALGIGPD---PRRRLSAPRIAEIVADELRRQIIDGELADGDLL
MAB_2272c|M.abscessus_ATCC_199 ------------------MQPVRRQTLIGQVTEQLREEIVSGRWAIGARI
:: :. .: * :
Mb3086c|M.bovis_AF2122/97 GSESALQQRFCVSRSVLREAVRLVEHHQVARMRRGPNGGLFICEPNAGPA
Rv3060c|M.tuberculosis_H37Rv GSESALQQRFCVSRSVLREAVRLVEHHQVARMRRGPNGGLFICEPNAGPA
MMAR_1630|M.marinum_M GSEGALQQRYGVSRSVLREAVRLVEHHQVARMRRGPNGGLLICAPDAGPA
MAV_3932|M.avium_104 GSEPALQQRFGVSRSVLREAVRLVEHHQVARMRRGPNGGLYICEPDAGPA
Mflv_2114|M.gilvum_PYR-GCK PNEAELMAHFGVSRPTLREAVRVLESERLVEVRRGSRTGARVRVPGPEIV
Mvan_4590|M.vanbaalenii_PYR-1 PNEAELMAHFGVSRPTLREAVRVLESERLVEVRRGSRTGARVRVPGPEIV
MSMEG_5201|M.smegmatis_MC2_155 PNEAELMSHFGVSRPTLREAVRVLESERLVEVRRGSRTGARVRVPGPEIV
TH_4408|M.thermoresistible__bu PPESELMERFGVSRPTLREAFRVLESESLIVIQRGVRGGARVTRPRRETL
MUL_3832|M.ulcerans_Agy99 PRQEVLVEQFNVSLVSLREALRILETEGLVSVRRGNRGGAVVHAPAKASA
MAB_2272c|M.abscessus_ATCC_199 PTEPELCELTGTSRNTIREAVQALVHAGMLERRQGS--GTYVLSLGG---
: * .* :***.: : : ::* * :
Mb3086c|M.bovis_AF2122/97 TRAVVIYLEYLGTTIGDLLGARLVLEPLAASLAAEH--IDEPGIERLRAV
Rv3060c|M.tuberculosis_H37Rv TRAVVIYLEYLGTTIGDLLGARLVLEPLAASLAAEH--IDEPGIERLRAV
MMAR_1630|M.marinum_M TRAVVIYLEYLGITLGELLDARLVFEPLAASLAAEH--IDEAGIDRLRAV
MAV_3932|M.avium_104 TRAVVIYLEYLGTTLADLLNARLVLEPLAASLAAER--IDEAGIARLRAV
Mflv_2114|M.gilvum_PYR-GCK ARPAGLLLELSGATIADLLTAKSAIEPMAARLLAES--GSAAAFDELEQL
Mvan_4590|M.vanbaalenii_PYR-1 ARPAGLLLELSGATIADLLTAKSGIEPMAARLLAES--GSPEAFDELERM
MSMEG_5201|M.smegmatis_MC2_155 ARPVGLLLELSGADIADLLVARSAIEPMAARLLAEN--GTEEQFAELDRM
TH_4408|M.thermoresistible__bu ARYAGLILEYEEVTLKDVYEARMTIEMPMVVELAKK--RDPAVIAELEAI
MUL_3832|M.ulcerans_Agy99 AYMLGLLLQSESVAVSDLGAALQELEPACAALAAQRPDRADTLVPELKRV
MAB_2272c|M.abscessus_ATCC_199 --SSAIADYFAAANNRDLIELRQTLEVTAAGLAAQR--RDEDDIEQLRAL
: :: :* . *: . .* :
Mb3086c|M.bovis_AF2122/97 LRAEERWRPG---LPPPPEQFYRVLAEQSKNPVLQLFIDILMRLTKRYVQ
Rv3060c|M.tuberculosis_H37Rv LRAEERWRPG---LPPPPEQFYRVLAEQSKNPVLQLFIDILMRLTKRYVQ
MMAR_1630|M.marinum_M LRAEEQRKPG---LPAVRDEFHVALARQSKNPVLQLFIEILMRLTRRYAL
MAV_3932|M.avium_104 LHAEQQWRPG---LPMPRDEFHIALAEQSKNPVLQLFIKVLMRLTTRYAL
Mflv_2114|M.gilvum_PYR-GCK LEELVADSHQSPRLAEATGAFHLRVVQLSGNATLSIVAGMLHEITVRHTA
Mvan_4590|M.vanbaalenii_PYR-1 LEELAADSHKSSRLAEATGLFHLRVVQLSGNATLSIVAGMLHEITVRHTA
MSMEG_5201|M.smegmatis_MC2_155 LEEHIPSDWQSDRLAETTGDFHRRVVELSGNATLGIIAGMLHEITVRHHQ
TH_4408|M.thermoresistible__bu VANESNLKPGSETVDQLT-DFHAAVARLSGNKTLQIVADMLHHIVKTANR
MUL_3832|M.ulcerans_Agy99 NEAMSEHLDDGAMFTEIGRQFHDLIVRGCGNHTIIAVVGSLETLWTSHEQ
MAB_2272c|M.abscessus_ATCC_199 LVRRNELWAPHHVEPHNVEEAISTDIAVHRAVVAASHNALYLELYDSLLG
. :
Mb3086c|M.bovis_AF2122/97 KSGTQSAG----EAVEAAGQVHNEHSDIVAAVTAGDSAWAKTLSERHVEA
Rv3060c|M.tuberculosis_H37Rv KSGTQSAG----EAVEAAGQVHNEHSDIVAAVTAGDSAWAKTLSERHVEA
MMAR_1630|M.marinum_M TSRTDTVA----EAFEAVDQMHNDHAAIAAAVTAGDSARAKTLSEQHVQQ
MAV_3932|M.avium_104 QSRTDSET----EALEAVDHLHTHHSRIVAAVTAGDPARAKTLSERHVEA
Mflv_2114|M.gilvum_PYR-GCK FVFNERRP----VSKADYETLLRSYRRLLQFLRSRDADGAEAHWRRHLDK
Mvan_4590|M.vanbaalenii_PYR-1 FVFNERRP----VSKADYDTLLRSYRKLMQFLRAGDAVGAEAHWRKHLDT
MSMEG_5201|M.smegmatis_MC2_155 FLFREHRP----VSKSDYDKLMRSYRKLMQIMRSGDGDAAEAHWRTHLDT
TH_4408|M.thermoresistible__bu SLQPTEGT----RAEQAVRRSAKTHRMVLELIKAGDAEKAGELWQRHLQK
MUL_3832|M.ulcerans_Agy99 QWADESAARGTYPSLAKRRAVLNAHIKLTETIAEGDVDRARRIAGRHLAD
MAB_2272c|M.abscessus_ATCC_199 LMDHYMRG----NPIGAECSFEHEHTRLVESVIAGDIGGATSATEQLFAE
. : : : * * .
Mb3086c|M.bovis_AF2122/97 VAGWLQQHQRGNDAAVRNGGRAREPRRAQQLILGAPRGKLAEVLAATIGD
Rv3060c|M.tuberculosis_H37Rv VAGWLQQHQRGNDAAVRNGGRAREPRRAQQLILGAPRGKLAEVLAATIGD
MMAR_1630|M.marinum_M VTGWLQQHQPGGDAKL-----AHVPRRSLRLDSETPPGKLAEVLAATIAD
MAV_3932|M.avium_104 VTAWLQRHHAGDRNRG------RTPRR--PLNSEVPQGKLAEMLAATIGD
Mflv_2114|M.gilvum_PYR-GCK TRELLLAG--------------------------LESVPVRDVMG-----
Mvan_4590|M.vanbaalenii_PYR-1 TRELLLTG--------------------------LESVPVRDVMG-----
MSMEG_5201|M.smegmatis_MC2_155 ARALMLQG--------------------------LESVKVRDVMG-----
TH_4408|M.thermoresistible__bu AEEFVLSG--------------------------AEMSTVVDLLE-----
MUL_3832|M.ulcerans_Agy99 TQTYVLSG--------------------------RAEQRIYALSPQALSR
MAB_2272c|M.abscessus_ATCC_199 LRLSRDQP-----------------------------GRNFPHHPHD---
Mb3086c|M.bovis_AF2122/97 DIAASGWQVGSVFGTETALLERYQVSRAVLREAVRLLEYHAIAHMRRGPG
Rv3060c|M.tuberculosis_H37Rv DIAASGWQVGSVFGTETALLERYQVSRAVLREAVRLLEYHAIAHMRRGPG
MMAR_1630|M.marinum_M DIAASGWQLDSVFGTETALLQRYRVSRAALREAVRLLEYHSVARMRRGPG
MAV_3932|M.avium_104 DIAADGWRVGSVFGTETALLQRYRVSRAVFREAVRLLEYHSIAHMRRGPG
Mflv_2114|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4590|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5201|M.smegmatis_MC2_155 --------------------------------------------------
TH_4408|M.thermoresistible__bu --------------------------------------------------
MUL_3832|M.ulcerans_Agy99 PRDMRRP-------------------------------------------
MAB_2272c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3086c|M.bovis_AF2122/97 GGLVVTTPQPQASIDTIALYLQYRKPSREDLRCVRDAIEIDNVAKVVKRR
Rv3060c|M.tuberculosis_H37Rv GGLVVTTPQPQASIDTIALYLQYRKPSREDLRCVRDAIEIDNVAKVVKRR
MMAR_1630|M.marinum_M GGLVVTKPQSQASIDTIALYLQYRQPSREDLRCVRDAIEIANVAKVVEQR
MAV_3932|M.avium_104 GGLVIAEPAAQASIDTIALYLQYRDPSREDLRCVRDAIEIDNVAKVVKRL
Mflv_2114|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4590|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5201|M.smegmatis_MC2_155 --------------------------------------------------
TH_4408|M.thermoresistible__bu --------------------------------------------------
MUL_3832|M.ulcerans_Agy99 --------------------------------------------------
MAB_2272c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3086c|M.bovis_AF2122/97 SEPEVASFLDTLGRP---RLDNPTDDVRAAAVEEFRFHVGLARAAGNTML
Rv3060c|M.tuberculosis_H37Rv SEPEVASFLDTLGRP---RLDNPTDDVRAAAVEEFRFHVGLARAAGNTML
MMAR_1630|M.marinum_M ARPEVASVLDELVVASDFAFEDAADAARKVAVEEFGFHVGLAQLAGNALL
MAV_3932|M.avium_104 AEPQVAAFVASRRSGLPDDSRQTPDDVRRAIAEEFDFHVGLAQLAGNAPL
Mflv_2114|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4590|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5201|M.smegmatis_MC2_155 --------------------------------------------------
TH_4408|M.thermoresistible__bu --------------------------------------------------
MUL_3832|M.ulcerans_Agy99 --------------------------------------------------
MAB_2272c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3086c|M.bovis_AF2122/97 DLFLLILVELFRRHLSSTEQALPTWSDVVAVGHAHVRILEAIGSGDDSLA
Rv3060c|M.tuberculosis_H37Rv DLFLLILVELFRRHLSSTEQALPTWSDVVAVGHAHVRILEAIGSGDDSLA
MMAR_1630|M.marinum_M DLFLRIIVELFQRHWSSTEHQQPTFNDVGAVEHAHQRIREAIIAGDDSLA
MAV_3932|M.avium_104 DLFLRIIVELFRRHWSSTGQALPTWSDVRAVHHAHLRIADAVAAGDLSVA
Mflv_2114|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4590|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5201|M.smegmatis_MC2_155 --------------------------------------------------
TH_4408|M.thermoresistible__bu --------------------------------------------------
MUL_3832|M.ulcerans_Agy99 --------------------------------------------------
MAB_2272c|M.abscessus_ATCC_199 --------------------------------------------------
Mb3086c|M.bovis_AF2122/97 RCRTRRHLDAAASWWL
Rv3060c|M.tuberculosis_H37Rv RCRTRRHLDAAASWWL
MMAR_1630|M.marinum_M RYRIRRHLDAAASWWL
MAV_3932|M.avium_104 SYRLRRHLDAAASWWL
Mflv_2114|M.gilvum_PYR-GCK ----------------
Mvan_4590|M.vanbaalenii_PYR-1 ----------------
MSMEG_5201|M.smegmatis_MC2_155 ----------------
TH_4408|M.thermoresistible__bu ----------------
MUL_3832|M.ulcerans_Agy99 ----------------
MAB_2272c|M.abscessus_ATCC_199 ----------------