For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. smegmatis MC2 155 MSMEG_0339 (-)

annotation: FMN-dependent monooxygenase
coordinates: 377377 - 378393
length: 338

LQLGYWAAQPPSNHAELVAAAEDAGFDTVFTAEAWGSDAFTPLAWWGRETSRLRLGTSVVQMSARTPTAC
AMASLTLDHLSGGRHILGLGVSGPQVVEGWYGQKFPKPLARTREYVDIIRQVWAREAPVTSDGPHYPLPL
AGAGTTGLGKALKPITHPLRADIPIMLGAEGPRNVALAAEICDGWLPIFYTPRMADTYNAWLDEGFAKPG
ARRTRETFEICATANIVITEDRAAAFAAMKPYLALYMGGMGAEDTNFHADVYRRMGYGEVVDEVTRLLRS
RGKEEAAQAIPDEVVDDAAIVGDVAYVREQIKVWEAAGVTTMVVNARSPEHIHQLTSL
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_0339--100% (338)FMN-dependent monooxygenase
M. smegmatis MC2 155MSMEG_5920-0.093.49% (338) FMN-dependent monooxygenase
M. smegmatis MC2 155MSMEG_1566-1e-6643.59% (312) oxidoreductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3550c-1e-16982.25% (338) coenzyme F420-dependent oxidoreductase
M. gilvum PYR-GCKMflv_1539-1e-17183.73% (338) luciferase family protein
M. tuberculosis H37RvRv3520c-1e-16982.25% (338) coenzyme F420-dependent oxidoreductase
M. leprae Br4923MLBr_00348-1e-16380.18% (338) putative coenzyme F420-dependent oxidoreductase
M. abscessus ATCC 19977MAB_4166c-1e-15475.44% (338) putative luciferase-like protein
M. marinum MMMAR_5005-1e-16882.54% (338) coenzyme F420-dependent oxidoreductase
M. avium 104MAV_0639-1e-17384.62% (338) FMN-dependent monooxygenase
M. thermoresistible (build 8)TH_2264-1e-16083.18% (321) POSSIBLE COENZYME F420-DEPENDENT OXIDOREDUCTASE
M. ulcerans Agy99MUL_4079-1e-16982.54% (338) coenzyme F420-dependent oxidoreductase
M. vanbaalenii PYR-1Mvan_5219-1e-17082.25% (338) luciferase family protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1539|M.gilvum_PYR-GCK          -------MKLGLQLGYWGAQPPENHAELVAAAEGAGFDTVFTAEAWGSDA
Mvan_5219|M.vanbaalenii_PYR-1       -------MKLGLQLGYWGAQAPTNHAELVATAEEVGFDTVFTAEAWGSDA
TH_2264|M.thermoresistible__bu      ----------------------------VAAAEEAGFDTVFTAEAWGSDA
MSMEG_0339|M.smegmatis_MC2_155      -----------MQLGYWAAQPPSNHAELVAAAEDAGFDTVFTAEAWGSDA
MMAR_5005|M.marinum_M               -------MKLGLQLGYWGAQPPENAGELVAAAEGAGFDAVFTAEAWGSDA
MUL_4079|M.ulcerans_Agy99           -------MKLGLQLGYWGAQPPENAGELVAAAEEAGFDAVFTAEAWGSDA
MAV_0639|M.avium_104                -------MKLGLQLGYWGAGPPENHGELVAAAEEAGYDAVFTAEAWGSDA
Mb3550c|M.bovis_AF2122/97           ---MEAGMKLGLQLGYWGAQPPQNHAELVAAAEDAGFDTVFTAEAWGSDA
Rv3520c|M.tuberculosis_H37Rv        ---MEAGMKLGLQLGYWGAQPPQNHAELVAAAEDAGFDTVFTAEAWGSDA
MLBr_00348|M.leprae_Br4923          MVERANAMKLGLQLGYWAAQPPGNAAELVAAAEGAGFDAVFTGEAWGSDA
MAB_4166c|M.abscessus_ATCC_199      -------MKFGLQLGYWSASPPENAGELVAAAEEGGFDAVFTAEAWGSDA
                                                                **:**  *:*:***.*******

Mflv_1539|M.gilvum_PYR-GCK          YTPLAWWGRETTRMRLGTSVIQLSARTPTACAMAALTLDHLSGGRHILGL
Mvan_5219|M.vanbaalenii_PYR-1       YTPLAWWGRETTRMRLGTSVIQLSARTPTACAMAALTLDHLSGGRHILGL
TH_2264|M.thermoresistible__bu      FTPLAWWGRQTTRMRLGTSVVQLSARTPTACAMASLTLDHLSGGRHILGL
MSMEG_0339|M.smegmatis_MC2_155      FTPLAWWGRETSRLRLGTSVVQMSARTPTACAMASLTLDHLSGGRHILGL
MMAR_5005|M.marinum_M               YTPLAWWGSSTQRLRLGTSVIQLSARTPTACAMAALTLDHLSGGRHILGL
MUL_4079|M.ulcerans_Agy99           YTPLAWWGSSTQRLRLGTSVIQLSARTPTACAMAALTLDHLSGGRHILGL
MAV_0639|M.avium_104                YTPLAWWGSSTSRVRLGTSVVQLSARTPTACAMAALTLDHLSGGRHILGL
Mb3550c|M.bovis_AF2122/97           YTPLAWWGSSTQRVRLGTSVIQLSARTPTACAMAALTLDHLSGGRHILGL
Rv3520c|M.tuberculosis_H37Rv        YTPLAWWGSSTQRVRLGTSVIQLSARTPTACAMAALTLDHLSGGRHILGL
MLBr_00348|M.leprae_Br4923          YTPLAWWGSSTQRVRLGTSVVQLSARTPTACAMAALTLDHLSGGRHILGL
MAB_4166c|M.abscessus_ATCC_199      YTPLAWWGSDTSRIRLGTSVIQLSARTPTACAMAALTLDHLSGGRHILGL
                                    :******* .* *:******:*:***********:***************

Mflv_1539|M.gilvum_PYR-GCK          GVSGPQVVEGWYGAKFPKPLARTREYVDILRQVWAREAPVHSDGPHYPLP
Mvan_5219|M.vanbaalenii_PYR-1       GVSGPQVVEGWYGAKFPKPLARTREYIDILRQVWAREAPVHSDGPHYPLP
TH_2264|M.thermoresistible__bu      GVSGPQVVEGWYGQRFPKPLARTREYIDIIRQVWAREAPVTSAGPHYPLP
MSMEG_0339|M.smegmatis_MC2_155      GVSGPQVVEGWYGQKFPKPLARTREYVDIIRQVWAREAPVTSDGPHYPLP
MMAR_5005|M.marinum_M               GVSGPQVVEGWYGQRFPKPLARTREYVDILRQVWAREGVVTSAGPHYPLP
MUL_4079|M.ulcerans_Agy99           GVSGPQVVEGWYGQRFPKPLARTREYVDILRQVWAREGVVTSDGPHYPLP
MAV_0639|M.avium_104                GVSGPQVVEGWYGQRFPKPLARTREYIDIIRQVWAREKPVTSDGPHYPLP
Mb3550c|M.bovis_AF2122/97           GVSGPQVVEGWYGQRFPKPLARTREYIDIVRQVWARESPVTSAGPHYRLP
Rv3520c|M.tuberculosis_H37Rv        GVSGPQVVEGWYGQRFPKPLARTREYIDIVRQVWARESPVTSAGPHYRLP
MLBr_00348|M.leprae_Br4923          GVSGPQVVEGWYGQPFPKPLSRTREYIDIVRQVWAREAPVVSDGQHYPLP
MAB_4166c|M.abscessus_ATCC_199      GVSGPQVVEGWYGQPFPKPLARTREYIDIIRQVLAREAPVRSDGPHYPLP
                                    *************  *****:*****:**:*** ***  * * * ** **

Mflv_1539|M.gilvum_PYR-GCK          LTGEGTTGLGKNLKPITHPLRSDIPVMLGAEGPKNVALAAEICDGWLPIF
Mvan_5219|M.vanbaalenii_PYR-1       LTGEGTTGLGKNLKPITHPLRADIPVMLGAEGPKNVALAAEICDGWLPIF
TH_2264|M.thermoresistible__bu      LTGEGTTGLGKALKPITHPLRADIPIMLGAEGPKNVALAAEIADGWLPIF
MSMEG_0339|M.smegmatis_MC2_155      LAGAGTTGLGKALKPITHPLRADIPIMLGAEGPRNVALAAEICDGWLPIF
MMAR_5005|M.marinum_M               LTGPGTTGLGKALKPITHPLRADIPIMLGAEGPKNVALAAEICDGWLPIF
MUL_4079|M.ulcerans_Agy99           LTGAGTTGLGKALKPITHPLRADIPIMLGAEGPKNVALAAEICDGWLPIF
MAV_0639|M.avium_104                LTGTGTTGLGKALKPITHPLRADIPIFLGAEGPKNVALAAEICDGWLPIF
Mb3550c|M.bovis_AF2122/97           LTGEGTTGLGKALKPITHPLRADIPIMLGAEGPKNVALAAEICDGWLPIF
Rv3520c|M.tuberculosis_H37Rv        LTGEGTTGLGKALKPITHPLRADIPIMLGAEGPKNVALAAEICDGWLPIF
MLBr_00348|M.leprae_Br4923          LTGAGATGLGKALKPITHPLRADIPIMLGAEGPKNVALAAEICDGWLPIF
MAB_4166c|M.abscessus_ATCC_199      LTGDKATGLGKPLKPIVHPLRSDIPIFLGAEGPKNVALTAEIADGWLPMF
                                    *:*  :***** ****.****:***::******:****:***.*****:*

Mflv_1539|M.gilvum_PYR-GCK          YSPRIAGMYNEWLDEGFARPGARRTRETFEICATAQVVVTDDRPAIMELM
Mvan_5219|M.vanbaalenii_PYR-1       YSPRIAAMYNEWLDEGFARPGARHTRETFEICATAQVVVTDDRAEMMELM
TH_2264|M.thermoresistible__bu      YSPRLADMYNEWLDEGFARPTARRSREDFEICATAQVVITDDRAGTMEMI
MSMEG_0339|M.smegmatis_MC2_155      YTPRMADTYNAWLDEGFAKPGARRTRETFEICATANIVITEDRAAAFAAM
MMAR_5005|M.marinum_M               YTPRMADMYNEWLDEGFARPGARRSRADFEICATAQVVVTEDRPAAFAAI
MUL_4079|M.ulcerans_Agy99           YTPRMADMYNEWLDEGFARPGARRSRADFEICATAQVVVTEDRPAAFAAI
MAV_0639|M.avium_104                YTPRLADMYNEWLDEGFARPGARRSRADFEICATANIVITEDRGAAFAAM
Mb3550c|M.bovis_AF2122/97           YSPRMAGMYNEWLDEGFARPGARRSREDFEICATAQVVITDDRAAAFAGI
Rv3520c|M.tuberculosis_H37Rv        YSPRMAGMYNEWLDEGFARPGARRSREDFEICATAQVVITDDRAAAFAGI
MLBr_00348|M.leprae_Br4923          FSPRMADMYNEWLDEGFARTGARRSREDFEICASAQIVVTEDRAAAFAGI
MAB_4166c|M.abscessus_ATCC_199      YAPRLADMYNEWLDEGFSRPGARRSREDFEIAATAQVIVTEDRRSVLDQL
                                    ::**:*  ** ******::. **::*  ***.*:*::::*:**   :  :

Mflv_1539|M.gilvum_PYR-GCK          KPHLALYMGGMGAEDTNFHADVYRRMGYAEVVDDVTRLFRSDRKDEAATV
Mvan_5219|M.vanbaalenii_PYR-1       KPHLALYMGGMGAEDTNFHADVYRRMGYAEVVDDVTKLFRSGRKDEAAKV
TH_2264|M.thermoresistible__bu      KPFLALYMGGMGAEEMNFHADVYRRMGYSEVVDDVTRLFRSGRKDEAAKV
MSMEG_0339|M.smegmatis_MC2_155      KPYLALYMGGMGAEDTNFHADVYRRMGYGEVVDEVTRLLRSRGKEEAAQA
MMAR_5005|M.marinum_M               KPFVALYMGGMGAEGTNFHADVYRRMGYAEVVDDVTKLFRSNRKDEAAEI
MUL_4079|M.ulcerans_Agy99           KPFVALYMGGMGAEGTNFHADAYRRMGYAEVVDDVTKLFRSNRKDEAAEI
MAV_0639|M.avium_104                KPYIALYMGGMGAEDTNFHADVYRRMGYAEVVDDVTKLFRSGRKDEAAKI
Mb3550c|M.bovis_AF2122/97           KPFLALYMGGMGAEETNFHADVYRRMGYTQVVDEVTKLFRSGRKDEAAEI
Rv3520c|M.tuberculosis_H37Rv        KPFLALYMGGMGAEETNFHADVYRRMGYTQVVDEVTKLFRSGRKDEAAEI
MLBr_00348|M.leprae_Br4923          KPFLALYMGGMGAEGTNFHADVYRRMGYAEVVDEVTALFRSNQKDKAAEI
MAB_4166c|M.abscessus_ATCC_199      KPFSALYIGGMGAVELNFHAEVYRRMGYGEVVDEVTELFRTNRKDKAAEA
                                    **. ***:*****   ****:.****** :***:** *:*:  *::**  

Mflv_1539|M.gilvum_PYR-GCK          IPDELVDDSAIVGDLAYVKEQITAWEAAGVTMMVVGARSPEQIRDLADLV
Mvan_5219|M.vanbaalenii_PYR-1       IPDELVDDSAIVGDLGYVQEQIKAWEAAGVTMMVVGARSPEQIRDLAALV
TH_2264|M.thermoresistible__bu      IPDELVDDAAIVGDIDYVRKQIAAWEAAGVTMMVVGARSVEQIRDLAALI
MSMEG_0339|M.smegmatis_MC2_155      IPDEVVDDAAIVGDVAYVREQIKVWEAAGVTTMVVNARSPEHIHQLTSL-
MMAR_5005|M.marinum_M               IPDELVDDAVIVGDADYVRKQIEVWEAAGVTMMVVSARSVEQVRELAGLV
MUL_4079|M.ulcerans_Agy99           IPDELVDDAVIVGDADYVRKQVEVWEAAGVTMMVVSARSVEQVRELAGLV
MAV_0639|M.avium_104                IPDEVIDDAAIVGDVDYVRKQIKAWEAAGVTMMVVSGRSTEQVRELATLI
Mb3550c|M.bovis_AF2122/97           IPDELVDDAVIVGDIDHVRKQMAVWEAAGVTMMVVTAGSAEQVRDLAALV
Rv3520c|M.tuberculosis_H37Rv        IPDELVDDAVIVGDIDHVRKQMAVWEAAGVTMMVVTAGSAEQVRDLAALV
MLBr_00348|M.leprae_Br4923          IPNELVDSTMIVGDVDYVCKQIAAWSAAGVTMMMVSASSVEQVRDLAGLF
MAB_4166c|M.abscessus_ATCC_199      IPDELVLDTTIVGTEAEVREQIKAWEAAGVTMLVVGCRSVEHVKQLSALT
                                    **:*:: .: ***    * :*: .*.***** ::*   * *::::*: * 

Mflv_1539|M.gilvum_PYR-GCK          --
Mvan_5219|M.vanbaalenii_PYR-1       --
TH_2264|M.thermoresistible__bu      --
MSMEG_0339|M.smegmatis_MC2_155      --
MMAR_5005|M.marinum_M               GG
MUL_4079|M.ulcerans_Agy99           GG
MAV_0639|M.avium_104                --
Mb3550c|M.bovis_AF2122/97           --
Rv3520c|M.tuberculosis_H37Rv        --
MLBr_00348|M.leprae_Br4923          --
MAB_4166c|M.abscessus_ATCC_199      --