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STTGRSVFGNVQLGYIVIETNRFSDWRRFGRDAIGLHVDDSLANTMRFRLDGNECRFLLQHGPAEDVTAL GWQLDDHNTFEEIINRVRRHGVPIIEGSAEQAALRGVARLARFPGPNGLTQEIYAQPRPCPAPLNIGARG GFVTGAGGIGHVAITSKRPDQVRGYFDTVFDARLSDFIDETIGGIKFKIRFLRVNQRHHSVAIAAANRLP INPIRTRVQHVNVQVADLDDLTASYQRIRELGFGLALSVGQHTNDRELSYYAVTPSGFEWELGWNPIVVD ESTWEPTTYQGISIWGHTPEGQHIIDKLAQFKTAGRSLLRREDNVAPLCGPARSSRCGESILTTT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1501 | - | - | 100% (346) | hypothetical protein MMAR_1501 |
| M. marinum M | MMAR_5063 | bphC | 7e-29 | 28.28% (297) | biphenyl-2,3-diol 1,2-dioxygenase BphC |
| M. marinum M | MMAR_2985 | bphC_1 | 7e-07 | 27.04% (159) | 2,3-dihydroxybiphenyl-1,2-dioxygenase BphC_1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3599c | bphC | 5e-29 | 29.19% (298) | putative biphenyl-2,3-diol 1,2-dioxygenase BPHC (23OHBP |
| M. gilvum PYR-GCK | Mflv_0675 | - | 4e-39 | 30.51% (295) | glyoxalase/bleomycin resistance protein/dioxygenase |
| M. tuberculosis H37Rv | Rv3568c | bphC | 5e-29 | 29.19% (298) | biphenyl-2,3-diol 1,2-dioxygenase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0585 | - | 6e-30 | 27.46% (295) | 2,3-dihydroxybiphenyl 1,2-dioxygenase |
| M. avium 104 | MAV_2516 | - | 1e-148 | 75.54% (323) | extradiol ring cleaving catechol dioxygenase |
| M. smegmatis MC2 155 | MSMEG_2891 | - | 3e-28 | 27.33% (300) | biphenyl-2,3-diol 1,2-dioxygenase 1 |
| M. thermoresistible (build 8) | TH_4499 | - | 2e-30 | 26.90% (290) | PUTATIVE biphenyl-2,3-diol 1,2-dioxygenase 1 |
| M. ulcerans Agy99 | MUL_4139 | bphC | 5e-29 | 28.28% (297) | biphenyl-2,3-diol 1,2-dioxygenase BphC |
| M. vanbaalenii PYR-1 | Mvan_0591 | - | 1e-135 | 66.77% (322) | glyoxalase/bleomycin resistance protein/dioxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3599c|M.bovis_AF2122/97 -------MS-IRSLGYLRIEATDMAAWREYGLKVLGMVEGKGAPEGALYL
Rv3568c|M.tuberculosis_H37Rv -------MS-IRSLGYLRIEATDMAAWREYGLKVLGMVEGKGAPEGALYL
MUL_4139|M.ulcerans_Agy99 -------MS-IRSLGYLRIEATDMAAWREYGLKVLGMVEGKGSTEGALYL
MAB_0585|M.abscessus_ATCC_1997 -------MSIIKALGYMRIQATDVAAWREFGTKVLGMMEGTGDDPAALYL
MSMEG_2891|M.smegmatis_MC2_155 ---------MIKSLGYVTVQATDMQRWRHFAFGVLGFAEGKGPDPDALYL
TH_4499|M.thermoresistible__bu MRHERDTMGFIKSLGYVIVQATDMDRWRHFAYEVLGFAEGTGPNPEALYL
Mflv_0675|M.gilvum_PYR-GCK --------MLVKTLGYVGVESPDAKEWLAFGPEVLG-MEAVEAASGSVLL
MMAR_1501|M.marinum_M MSTTGRSVFGNVQLGYIVIETNRFSDWRRFGRDAIG-LHVDDSLANTMRF
MAV_2516|M.avium_104 -----MNIFGNVHLGYLVIETDRFADWRRFGRDAIG-MHLDDVLPDAMRF
Mvan_0591|M.vanbaalenii_PYR-1 ---MTPDVFGKVHLGYLVIESDRFADWRRFGRDAIG-MHLDETLTDVMRF
***: ::: * :. .:* . : :
Mb3599c|M.bovis_AF2122/97 RMDDFPARLVVVPGEHDRLLEAGWECANAEGLQEIRNRLDLEGTPYKEAT
Rv3568c|M.tuberculosis_H37Rv RMDDFPARLVVVPGEHDRLLEAGWECANAEGLQEIRNRLDLEGTPYKEAT
MUL_4139|M.ulcerans_Agy99 RMDDFPARLVIVPGTQDRLAEAGWECADAQGLQEIRNRLDVEGTPYKEAT
MAB_0585|M.abscessus_ATCC_1997 RMDDFAARLVIVPGESDRLLASGWEVADAPALQAVRERLAKAGVEYAEGD
MSMEG_2891|M.smegmatis_MC2_155 RMDERCARIIVTPGDVDKIVTVGWEVRDHAALQEVKRALDAAGVPHKQLS
TH_4499|M.thermoresistible__bu RMDERTARITVEPGEVDRIVTIGWEVRDHAALEDVKRALAAAGVPHRQLS
Mflv_0675|M.gilvum_PYR-GCK RIDDADHRLAVHHGDRNRMLYAGWDVGSEEALEAAGELLHKRGIGFEVGT
MMAR_1501|M.marinum_M RLDGNECRFLLQHGPAEDVTALGWQLDDHNTFEEIINRVRRHGVPIIEGS
MAV_2516|M.avium_104 RLDDNACRFLLQRGAGEDVTALGWQLDDHATFEEILARLTRHEMPVTEGT
Mvan_0591|M.vanbaalenii_PYR-1 RLDDNACRFLLTRGPAEDTTALGWEVGDHDTFDAIAARIHDHGVPVSDGA
*:* *: : * : **: . :: :
Mb3599c|M.bovis_AF2122/97 AAELADRRVDEMIRFADPSGNCLEVFHGTALEHRRVVSPYGHR-FVTGEQ
Rv3568c|M.tuberculosis_H37Rv AAELADRRVDEMIRFADPSGNCLEVFHGTALEHRRVVSPYGHR-FVTGEQ
MUL_4139|M.ulcerans_Agy99 AAELADRRVDEMILFSDPSGNPLAVFHGAALEHRRVVSPYGHK-FVTGEQ
MAB_0585|M.abscessus_ATCC_1997 KAEVSDRKVEAFIQFSDPSGNTLEVFHGAQYMGRRFVSPYGHK-FVTAEQ
MSMEG_2891|M.smegmatis_MC2_155 LAEADSRRVEEAIAFEDPAGTSLEVFHGPVLDHSPVVTPFGAR-FVTGDQ
TH_4499|M.thermoresistible__bu TAEADARRVEEVVAFADPAGTALEVFHGPVLDHSPVVTPFGAR-FVTGDQ
Mflv_0675|M.gilvum_PYR-GCK EEDCAARGVLGFVTLSDPSGLRHELFYGQKVVPGSFRPGRAISGFVTGAQ
MMAR_1501|M.marinum_M AEQAALRGVARLARFPGPNGLTQEIYAQPRPCPAPLNIGARGG-FVTGAG
MAV_2516|M.avium_104 PEQAALRGVDRLVRFPGPNGLAHEIFTRARIGHTPLDMRVGGG-FVTGEG
Mvan_0591|M.vanbaalenii_PYR-1 AEEAEIRGVEHFIRFPGPNGLLQELYVTPRKGLQHLRLGVAGG-FVTGVD
: * * : .* * :: . ***.
Mb3599c|M.bovis_AF2122/97 GMGHVVLSTRDDAEALHFYRDVLGFRLRDSMRLPPRMVGRPADGPPAWLR
Rv3568c|M.tuberculosis_H37Rv GMGHVVLSTRDDAEALHFYRDVLGFRLRDSMRLPPQMVGRPADGPPAWLR
MUL_4139|M.ulcerans_Agy99 GLGHVVLTTRDDAEALHFYRDVLGFKLRDSMRMPPQVVGRPADGAPAWLR
MAB_0585|M.abscessus_ATCC_1997 GLGHVVLTCTDDVAAQEFYQDVLGFQLRDSMKLPPQLVGRPADGDPVWLR
MSMEG_2891|M.smegmatis_MC2_155 GLGHVVLPALDVNGLFEFYTETLGFKSRGAFRVP-----VPPEFGPVRVR
TH_4499|M.thermoresistible__bu GLGHVVLPTVDVDGLFEFYTEVLGFRSRGAFRVP-----APEEFGPVRVR
Mflv_0675|M.gilvum_PYR-GCK GLGHVVLATPDLAQADRFLRGVLGFKKSD------------EIYTFMDLW
MMAR_1501|M.marinum_M GIGHVAITSKRPDQVRGYFDTVFDARLSDFIDET-------IGGIKFKIR
MAV_2516|M.avium_104 GMGHVAIVSKEPQQMRGYYDTVFDARLSDYIDET-------ISGLKFKIR
Mvan_0591|M.vanbaalenii_PYR-1 GMGHVAIATKKPHQMHGYYRTVFDARLSDYIDET-------ISGLKFKIR
*:***.: : .:. : . :
Mb3599c|M.bovis_AF2122/97 FFGCNPRHHSLAFLPMPTS------SGIVHLMVEVEQADDVGLCLDRALR
Rv3568c|M.tuberculosis_H37Rv FFGCNPRHHSLAFLPMPTS------SGIVHLMVEVEQADDVGLCLDRALR
MUL_4139|M.ulcerans_Agy99 FFGCNPRHHSLAFLPLPTP------SGIVHLMVEVQNSDDVGLCLDRALR
MAB_0585|M.abscessus_ATCC_1997 FYGCNPRHHALAFMPMPNP------TGIVHLMVEVENSDDVGLCLDRANR
MSMEG_2891|M.smegmatis_MC2_155 FLGVNERHHSLALCPASTLRD----PGLVHLMVEVDSLDAVGQALDRVNA
TH_4499|M.thermoresistible__bu FLGINERHHSLALCPASTLRD----PGLIHLMVEVDTLDAVGQALDRVNR
Mflv_0675|M.gilvum_PYR-GCK FYHCNPRHHSIALTPMPGVR------GLHHVMVEVQSFDDVGMAYDLCMS
MMAR_1501|M.marinum_M FLRVNQRHHSVAIAAANRLPINPIRTRVQHVNVQVADLDDLTASYQRIRE
MAV_2516|M.avium_104 FLRVNQRHHSVAIAAANRLPINPIRTRIQHCNIQVGDLDDMTASYQRVKA
Mvan_0591|M.vanbaalenii_PYR-1 FLRVNERHHSVAIASVNRLPLNPIRTRIQHCNIQVAELDDMASAYRRVKE
* * ***::*: . : * ::* * : .
Mb3599c|M.bovis_AF2122/97 RKVPMSATLGRHVNDLMLSFYMKTPGGFDIEFGCEGRQVDDRDWIAREST
Rv3568c|M.tuberculosis_H37Rv RKVPMSATLGRHVNDLMLSFYMKTPGGFDIEFGCEGRQVDDRDWIAREST
MUL_4139|M.ulcerans_Agy99 RKVPMSATLGRHVNDLMLSFYMKTPGGFDVEFGCEGRQVDDHDWIAREST
MAB_0585|M.abscessus_ATCC_1997 RKVKMSATLGRHINDKMLSFYMKTPGGFDMEFGCEGMEVDDESWVARESV
MSMEG_2891|M.smegmatis_MC2_155 DGFQLSSTLGRHTNDKMVSFYVRAPGDWDIEFGTDGMRVDEQHYTAEEIT
TH_4499|M.thermoresistible__bu DGYQLSSTLGRHTNDKMVSFYVRAPGDWDIEFGTAGMRVDETYYTAEEIT
Mflv_0675|M.gilvum_PYR-GCK RNIPLSMTLGRHVNDRMVSFYARTPSGFDIEYGWDAVTVDDDTWTVAQYD
MMAR_1501|M.marinum_M LGFGLALSVGQHTNDRELSYYAVTPSGFEWELGWNPIVVDESTWEPTTYQ
MAV_2516|M.avium_104 LGFKMALSVGQHTNDRELSYYAISPSGFEWEVGWNPVVVDENTWEPTTYQ
Mvan_0591|M.vanbaalenii_PYR-1 LGFEMALSVGQHTNDKELSFYAVTPSGFEWEVGWNPIVVDEATWEPTTHQ
:: ::*:* ** :*:* :*..:: * * **: :
Mb3599c|M.bovis_AF2122/97 AVSLWGHDFTVGARG-----------------------------------
Rv3568c|M.tuberculosis_H37Rv AVSLWGHDFTVGARG-----------------------------------
MUL_4139|M.ulcerans_Agy99 AVSLWGHDFTVGARG-----------------------------------
MAB_0585|M.abscessus_ATCC_1997 GVSLWGHDFSVGFK------------------------------------
MSMEG_2891|M.smegmatis_MC2_155 ADSYWGHQWVSDLPRAMQP-------------------------------
TH_4499|M.thermoresistible__bu ADSYWGHQWVGDLPAAMRP-------------------------------
Mflv_0675|M.gilvum_PYR-GCK RPSVWGHQMVAQTPPGALEAATT---------------------------
MMAR_1501|M.marinum_M GISIWGHTPEGQHIIDKLAQFKTAGRSLLRREDNVAPLCGPARSSRCGES
MAV_2516|M.avium_104 GISIWGHTPEGQTIIDKLAQFKSAAISLLHRENTVPALARTGIPDD----
Mvan_0591|M.vanbaalenii_PYR-1 GISLWGHTPEGHTIVNLLERFKAGARSVFHAEDSVPALV-----------
* ***
Mb3599c|M.bovis_AF2122/97 -----
Rv3568c|M.tuberculosis_H37Rv -----
MUL_4139|M.ulcerans_Agy99 -----
MAB_0585|M.abscessus_ATCC_1997 -----
MSMEG_2891|M.smegmatis_MC2_155 -----
TH_4499|M.thermoresistible__bu -----
Mflv_0675|M.gilvum_PYR-GCK -----
MMAR_1501|M.marinum_M ILTTT
MAV_2516|M.avium_104 -----
Mvan_0591|M.vanbaalenii_PYR-1 -----