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TPDVFGKVHLGYLVIESDRFADWRRFGRDAIGMHLDETLTDVMRFRLDDNACRFLLTRGPAEDTTALGWE VGDHDTFDAIAARIHDHGVPVSDGAAEEAEIRGVEHFIRFPGPNGLLQELYVTPRKGLQHLRLGVAGGFV TGVDGMGHVAIATKKPHQMHGYYRTVFDARLSDYIDETISGLKFKIRFLRVNERHHSVAIASVNRLPLNP IRTRIQHCNIQVAELDDMASAYRRVKELGFEMALSVGQHTNDKELSFYAVTPSGFEWEVGWNPIVVDEAT WEPTTHQGISLWGHTPEGHTIVNLLERFKAGARSVFHAEDSVPALV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0591 | - | - | 100% (327) | glyoxalase/bleomycin resistance protein/dioxygenase |
| M. vanbaalenii PYR-1 | Mvan_0545 | - | 2e-41 | 32.21% (298) | glyoxalase/bleomycin resistance protein/dioxygenase |
| M. vanbaalenii PYR-1 | Mvan_0470 | - | 2e-41 | 32.21% (298) | glyoxalase/bleomycin resistance protein/dioxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3599c | bphC | 5e-35 | 32.20% (295) | putative biphenyl-2,3-diol 1,2-dioxygenase BPHC (23OHBP |
| M. gilvum PYR-GCK | Mflv_0675 | - | 2e-41 | 32.21% (298) | glyoxalase/bleomycin resistance protein/dioxygenase |
| M. tuberculosis H37Rv | Rv3568c | bphC | 5e-35 | 32.20% (295) | biphenyl-2,3-diol 1,2-dioxygenase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0585 | - | 7e-36 | 31.63% (294) | 2,3-dihydroxybiphenyl 1,2-dioxygenase |
| M. marinum M | MMAR_1501 | - | 1e-135 | 66.77% (322) | hypothetical protein MMAR_1501 |
| M. avium 104 | MAV_2516 | - | 1e-142 | 71.52% (323) | extradiol ring cleaving catechol dioxygenase |
| M. smegmatis MC2 155 | MSMEG_6036 | - | 7e-34 | 31.19% (295) | biphenyl-2,3-diol 1,2-dioxygenase |
| M. thermoresistible (build 8) | TH_1740 | - | 1e-34 | 31.53% (295) | PROBABLE BIPHENYL-2,3-DIOL 1,2-DIOXYGENASE BPHC (23OHBP |
| M. ulcerans Agy99 | MUL_4139 | bphC | 1e-34 | 32.54% (295) | biphenyl-2,3-diol 1,2-dioxygenase BphC |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_6036|M.smegmatis_MC2_155 -------MS-IKSLGYLRIEATDVAAWREYGLKVLGMVEGKGNTDGALYL
TH_1740|M.thermoresistible__bu -------MS-IRSLGYLRIEATDVAAWREYGLKVLGMVEGKGPTEGALYL
Mb3599c|M.bovis_AF2122/97 -------MS-IRSLGYLRIEATDMAAWREYGLKVLGMVEGKGAPEGALYL
Rv3568c|M.tuberculosis_H37Rv -------MS-IRSLGYLRIEATDMAAWREYGLKVLGMVEGKGAPEGALYL
MUL_4139|M.ulcerans_Agy99 -------MS-IRSLGYLRIEATDMAAWREYGLKVLGMVEGKGSTEGALYL
MAB_0585|M.abscessus_ATCC_1997 -------MSIIKALGYMRIQATDVAAWREFGTKVLGMMEGTGDDPAALYL
Mflv_0675|M.gilvum_PYR-GCK -------ML-VKTLGYVGVESPDAKEWLAFGPEVLGMEAVEAAS-GSVLL
MMAR_1501|M.marinum_M MSTTGRSVFGNVQLGYIVIETNRFSDWRRFGRDAIGLH-VDDSLANTMRF
MAV_2516|M.avium_104 -----MNIFGNVHLGYLVIETDRFADWRRFGRDAIGMH-LDDVLPDAMRF
Mvan_0591|M.vanbaalenii_PYR-1 ---MTPDVFGKVHLGYLVIESDRFADWRRFGRDAIGMH-LDETLTDVMRF
: ***: ::: * :* ..:*: : :
MSMEG_6036|M.smegmatis_MC2_155 RMDEFPARLVIVPGEHDRLQVSGWEAANAAELQDIRSRLDAAGTPFKEGT
TH_1740|M.thermoresistible__bu RMDEFPARLVIVPGERDRLLESGWECANAEGLQDVRSRLEAAGVPYKEGT
Mb3599c|M.bovis_AF2122/97 RMDDFPARLVVVPGEHDRLLEAGWECANAEGLQEIRNRLDLEGTPYKEAT
Rv3568c|M.tuberculosis_H37Rv RMDDFPARLVVVPGEHDRLLEAGWECANAEGLQEIRNRLDLEGTPYKEAT
MUL_4139|M.ulcerans_Agy99 RMDDFPARLVIVPGTQDRLAEAGWECADAQGLQEIRNRLDVEGTPYKEAT
MAB_0585|M.abscessus_ATCC_1997 RMDDFAARLVIVPGESDRLLASGWEVADAPALQAVRERLAKAGVEYAEGD
Mflv_0675|M.gilvum_PYR-GCK RIDDADHRLAVHHGDRNRMLYAGWDVGSEEALEAAGELLHKRGIGFEVGT
MMAR_1501|M.marinum_M RLDGNECRFLLQHGPAEDVTALGWQLDDHNTFEEIINRVRRHGVPIIEGS
MAV_2516|M.avium_104 RLDDNACRFLLQRGAGEDVTALGWQLDDHATFEEILARLTRHEMPVTEGT
Mvan_0591|M.vanbaalenii_PYR-1 RLDDNACRFLLTRGPAEDTTALGWEVGDHDTFDAIAARIHDHGVPVSDGA
*:* *: : * : **: . :: : .
MSMEG_6036|M.smegmatis_MC2_155 SAELAERRVDEMIVFDDPSGNTLEVFHGVALEHRRVVSPYGHK-FVTEEQ
TH_1740|M.thermoresistible__bu AAELADRRVVELIRFQDPSGNTLEAFHTVALEHRRVVSPYGHR-FVTGEQ
Mb3599c|M.bovis_AF2122/97 AAELADRRVDEMIRFADPSGNCLEVFHGTALEHRRVVSPYGHR-FVTGEQ
Rv3568c|M.tuberculosis_H37Rv AAELADRRVDEMIRFADPSGNCLEVFHGTALEHRRVVSPYGHR-FVTGEQ
MUL_4139|M.ulcerans_Agy99 AAELADRRVDEMILFSDPSGNPLAVFHGAALEHRRVVSPYGHK-FVTGEQ
MAB_0585|M.abscessus_ATCC_1997 KAEVSDRKVEAFIQFSDPSGNTLEVFHGAQYMGRRFVSPYGHK-FVTAEQ
Mflv_0675|M.gilvum_PYR-GCK EEDCAARGVLGFVTLSDPSGLRHELFYGQKVVPGSFRPGRAISGFVTGAQ
MMAR_1501|M.marinum_M AEQAALRGVARLARFPGPNGLTQEIYAQPRPCPAPLNIGARGG-FVTGAG
MAV_2516|M.avium_104 PEQAALRGVDRLVRFPGPNGLAHEIFTRARIGHTPLDMRVGGG-FVTGEG
Mvan_0591|M.vanbaalenii_PYR-1 AEEAEIRGVEHFIRFPGPNGLLQELYVTPRKGLQHLRLGVAGG-FVTGVD
: * * : : .*.* : . ***
MSMEG_6036|M.smegmatis_MC2_155 GLGHVVLTTKDDRETLHFYRDILGFSLRDSMKLPPQLVGRPADGEPAWLR
TH_1740|M.thermoresistible__bu GLGHVVLTTRDDAESLRFYRDVLGFYLRDSMRLPPQLVGRPADGEPAWLR
Mb3599c|M.bovis_AF2122/97 GMGHVVLSTRDDAEALHFYRDVLGFRLRDSMRLPPRMVGRPADGPPAWLR
Rv3568c|M.tuberculosis_H37Rv GMGHVVLSTRDDAEALHFYRDVLGFRLRDSMRLPPQMVGRPADGPPAWLR
MUL_4139|M.ulcerans_Agy99 GLGHVVLTTRDDAEALHFYRDVLGFKLRDSMRMPPQVVGRPADGAPAWLR
MAB_0585|M.abscessus_ATCC_1997 GLGHVVLTCTDDVAAQEFYQDVLGFQLRDSMKLPPQLVGRPADGDPVWLR
Mflv_0675|M.gilvum_PYR-GCK GLGHVVLATPDLAQADRFLRGVLGFKKSDEIYTFMD------------LW
MMAR_1501|M.marinum_M GIGHVAITSKRPDQVRGYFDTVFDARLSDFIDETIG-------GIKFKIR
MAV_2516|M.avium_104 GMGHVAIVSKEPQQMRGYYDTVFDARLSDYIDETIS-------GLKFKIR
Mvan_0591|M.vanbaalenii_PYR-1 GMGHVAIATKKPHQMHGYYRTVFDARLSDYIDETIS-------GLKFKIR
*:***.: : ::. * : :
MSMEG_6036|M.smegmatis_MC2_155 FLGVNPRHHSLAFMPG------QTPSGIVHLMVEVENSDDVGLCLDRALR
TH_1740|M.thermoresistible__bu FFGCNPRHHSLAFMPG------ETPSGIVHLMVEVENSDDVGLCLDRALR
Mb3599c|M.bovis_AF2122/97 FFGCNPRHHSLAFLPM------PTSSGIVHLMVEVEQADDVGLCLDRALR
Rv3568c|M.tuberculosis_H37Rv FFGCNPRHHSLAFLPM------PTSSGIVHLMVEVEQADDVGLCLDRALR
MUL_4139|M.ulcerans_Agy99 FFGCNPRHHSLAFLPL------PTPSGIVHLMVEVQNSDDVGLCLDRALR
MAB_0585|M.abscessus_ATCC_1997 FYGCNPRHHALAFMPM------PNPTGIVHLMVEVENSDDVGLCLDRANR
Mflv_0675|M.gilvum_PYR-GCK FYHCNPRHHSIALTPM------PGVRGLHHVMVEVQSFDDVGMAYDLCMS
MMAR_1501|M.marinum_M FLRVNQRHHSVAIAAANRLPINPIRTRVQHVNVQVADLDDLTASYQRIRE
MAV_2516|M.avium_104 FLRVNQRHHSVAIAAANRLPINPIRTRIQHCNIQVGDLDDMTASYQRVKA
Mvan_0591|M.vanbaalenii_PYR-1 FLRVNERHHSVAIASVNRLPLNPIRTRIQHCNIQVAELDDMASAYRRVKE
* * ***::*: . : * ::* . **: .
MSMEG_6036|M.smegmatis_MC2_155 RKVKMSATLGRHVNDKMLSFYMKTPGGFDIEFGCEGLEVDDDNWVAREST
TH_1740|M.thermoresistible__bu RKVPMSATLGRHVNDKMLSFYMKTPGGFDVEFGCEGLQVDDEEWVAREST
Mb3599c|M.bovis_AF2122/97 RKVPMSATLGRHVNDLMLSFYMKTPGGFDIEFGCEGRQVDDRDWIAREST
Rv3568c|M.tuberculosis_H37Rv RKVPMSATLGRHVNDLMLSFYMKTPGGFDIEFGCEGRQVDDRDWIAREST
MUL_4139|M.ulcerans_Agy99 RKVPMSATLGRHVNDLMLSFYMKTPGGFDVEFGCEGRQVDDHDWIAREST
MAB_0585|M.abscessus_ATCC_1997 RKVKMSATLGRHINDKMLSFYMKTPGGFDMEFGCEGMEVDDESWVARESV
Mflv_0675|M.gilvum_PYR-GCK RNIPLSMTLGRHVNDRMVSFYARTPSGFDIEYGWDAVTVDDDTWTVAQYD
MMAR_1501|M.marinum_M LGFGLALSVGQHTNDRELSYYAVTPSGFEWELGWNPIVVDESTWEPTTYQ
MAV_2516|M.avium_104 LGFKMALSVGQHTNDRELSYYAISPSGFEWEVGWNPVVVDENTWEPTTYQ
Mvan_0591|M.vanbaalenii_PYR-1 LGFEMALSVGQHTNDKELSFYAVTPSGFEWEVGWNPIVVDEATWEPTTHQ
. :: ::*:* ** :*:* :*.**: * * : **: *
MSMEG_6036|M.smegmatis_MC2_155 AVSLWGHDFSVGFK------------------------------------
TH_1740|M.thermoresistible__bu AVSLWGHDFSIGFKG-----------------------------------
Mb3599c|M.bovis_AF2122/97 AVSLWGHDFTVGARG-----------------------------------
Rv3568c|M.tuberculosis_H37Rv AVSLWGHDFTVGARG-----------------------------------
MUL_4139|M.ulcerans_Agy99 AVSLWGHDFTVGARG-----------------------------------
MAB_0585|M.abscessus_ATCC_1997 GVSLWGHDFSVGFK------------------------------------
Mflv_0675|M.gilvum_PYR-GCK RPSVWGHQMVAQTPPGALEAATT---------------------------
MMAR_1501|M.marinum_M GISIWGHTPEGQHIIDKLAQFKTAGRSLLRREDNVAPLCGPARSSRCGES
MAV_2516|M.avium_104 GISIWGHTPEGQTIIDKLAQFKSAAISLLHRENTVPALARTGIPDD----
Mvan_0591|M.vanbaalenii_PYR-1 GISLWGHTPEGHTIVNLLERFKAGARSVFHAEDSVPALV-----------
*:***
MSMEG_6036|M.smegmatis_MC2_155 -----
TH_1740|M.thermoresistible__bu -----
Mb3599c|M.bovis_AF2122/97 -----
Rv3568c|M.tuberculosis_H37Rv -----
MUL_4139|M.ulcerans_Agy99 -----
MAB_0585|M.abscessus_ATCC_1997 -----
Mflv_0675|M.gilvum_PYR-GCK -----
MMAR_1501|M.marinum_M ILTTT
MAV_2516|M.avium_104 -----
Mvan_0591|M.vanbaalenii_PYR-1 -----