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SIRSLGYLRIEATDMAAWREYGLKVLGMVEGKGSTEGALYLRMDDFPARLVIVPGTQDRLAEAGWECADA QGLQEIRNRLDVEGTPYKEATAAELADRRVDEMILFSDPSGNPLAVFHGAALEHRRVVSPYGHKFVTGEQ GLGHVVLTTRDDAEALHFYRDVLGFKLRDSMRMPPQVVGRPADGAPAWLRFFGCNPRHHSLAFLPLPTPS GIVHLMVEVQNSDDVGLCLDRALRRKVPMSATLGRHVNDLMLSFYMKTPGGFDVEFGCEGRQVDDHDWIA RESTAVSLWGHDFTVGARG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_5063 | bphC | - | 100% (300) | biphenyl-2,3-diol 1,2-dioxygenase BphC |
| M. marinum M | MMAR_1501 | - | 6e-29 | 28.28% (297) | hypothetical protein MMAR_1501 |
| M. marinum M | MMAR_2985 | bphC_1 | 3e-08 | 23.34% (317) | 2,3-dihydroxybiphenyl-1,2-dioxygenase BphC_1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3599c | bphC | 1e-164 | 90.33% (300) | putative biphenyl-2,3-diol 1,2-dioxygenase BPHC (23OHBP |
| M. gilvum PYR-GCK | Mflv_1465 | - | 1e-150 | 84.18% (297) | glyoxalase/bleomycin resistance protein/dioxygenase |
| M. tuberculosis H37Rv | Rv3568c | bphC | 1e-164 | 90.67% (300) | biphenyl-2,3-diol 1,2-dioxygenase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0585 | - | 1e-128 | 72.20% (295) | 2,3-dihydroxybiphenyl 1,2-dioxygenase |
| M. avium 104 | MAV_0593 | - | 1e-163 | 90.64% (299) | extradiol ring-cleavage dioxygenase |
| M. smegmatis MC2 155 | MSMEG_6036 | - | 1e-147 | 82.49% (297) | biphenyl-2,3-diol 1,2-dioxygenase |
| M. thermoresistible (build 8) | TH_1740 | - | 1e-153 | 84.67% (300) | PROBABLE BIPHENYL-2,3-DIOL 1,2-DIOXYGENASE BPHC (23OHBP |
| M. ulcerans Agy99 | MUL_4139 | bphC | 1e-178 | 100.00% (300) | biphenyl-2,3-diol 1,2-dioxygenase BphC |
| M. vanbaalenii PYR-1 | Mvan_5306 | - | 1e-149 | 83.84% (297) | glyoxalase/bleomycin resistance protein/dioxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1465|M.gilvum_PYR-GCK MT---IKSLGYLRIESTDVAAWREYGLKVLGMVEGSGPTEGALYLRMDEF
Mvan_5306|M.vanbaalenii_PYR-1 MT---IKSLGYLRIESTDVAAWREYGLKVLGMVEGSGSTEGALYLRMDEF
MSMEG_6036|M.smegmatis_MC2_155 MS---IKSLGYLRIEATDVAAWREYGLKVLGMVEGKGNTDGALYLRMDEF
MMAR_5063|M.marinum_M MS---IRSLGYLRIEATDMAAWREYGLKVLGMVEGKGSTEGALYLRMDDF
MUL_4139|M.ulcerans_Agy99 MS---IRSLGYLRIEATDMAAWREYGLKVLGMVEGKGSTEGALYLRMDDF
Mb3599c|M.bovis_AF2122/97 MS---IRSLGYLRIEATDMAAWREYGLKVLGMVEGKGAPEGALYLRMDDF
Rv3568c|M.tuberculosis_H37Rv MS---IRSLGYLRIEATDMAAWREYGLKVLGMVEGKGAPEGALYLRMDDF
MAV_0593|M.avium_104 MSNGAIRSLGYLRIEATDMAAWRDYGLKVLGMVEGKGDTEGALYLRMDDF
TH_1740|M.thermoresistible__bu MS---IRSLGYLRIEATDVAAWREYGLKVLGMVEGKGPTEGALYLRMDEF
MAB_0585|M.abscessus_ATCC_1997 MS--IIKALGYMRIQATDVAAWREFGTKVLGMMEGTGDDPAALYLRMDDF
*: *::***:**::**:****::* *****:**.* .*******:*
Mflv_1465|M.gilvum_PYR-GCK PARLIIVPGENDRLLESGWETANAAALQDIRARLDIHGTPYKEATASQLA
Mvan_5306|M.vanbaalenii_PYR-1 PARLVIVPGERDRLLVSGWETANASQLQDIRKRLEVEGTPYKEATATQLA
MSMEG_6036|M.smegmatis_MC2_155 PARLVIVPGEHDRLQVSGWEAANAAELQDIRSRLDAAGTPFKEGTSAELA
MMAR_5063|M.marinum_M PARLVIVPGTQDRLAEAGWECADAQGLQEIRNRLDVEGTPYKEATAAELA
MUL_4139|M.ulcerans_Agy99 PARLVIVPGTQDRLAEAGWECADAQGLQEIRNRLDVEGTPYKEATAAELA
Mb3599c|M.bovis_AF2122/97 PARLVVVPGEHDRLLEAGWECANAEGLQEIRNRLDLEGTPYKEATAAELA
Rv3568c|M.tuberculosis_H37Rv PARLVVVPGEHDRLLEAGWECANAEGLQEIRNRLDLEGTPYKEATAAELA
MAV_0593|M.avium_104 PARLVIVPGERDHLLEAGWECANAEGLQEIRDRLDMEGVPYKEATAAQLA
TH_1740|M.thermoresistible__bu PARLVIVPGERDRLLESGWECANAEGLQDVRSRLEAAGVPYKEGTAAELA
MAB_0585|M.abscessus_ATCC_1997 AARLVIVPGESDRLLASGWEVADAPALQAVRERLAKAGVEYAEGDKAEVS
.***::*** *:* :*** *:* ** :* ** *. : *. ::::
Mflv_1465|M.gilvum_PYR-GCK DRRVDEMIIFDDPSGNTLEVFHGVALEHRRVVSPYGHKFVTEEQGLGHVV
Mvan_5306|M.vanbaalenii_PYR-1 ERRVDEMIIFDDPSGNTLEVFHGVALEHRRVVSPYGHKFVTEEQGLGHVV
MSMEG_6036|M.smegmatis_MC2_155 ERRVDEMIVFDDPSGNTLEVFHGVALEHRRVVSPYGHKFVTEEQGLGHVV
MMAR_5063|M.marinum_M DRRVDEMILFSDPSGNPLAVFHGAALEHRRVVSPYGHKFVTGEQGLGHVV
MUL_4139|M.ulcerans_Agy99 DRRVDEMILFSDPSGNPLAVFHGAALEHRRVVSPYGHKFVTGEQGLGHVV
Mb3599c|M.bovis_AF2122/97 DRRVDEMIRFADPSGNCLEVFHGTALEHRRVVSPYGHRFVTGEQGMGHVV
Rv3568c|M.tuberculosis_H37Rv DRRVDEMIRFADPSGNCLEVFHGTALEHRRVVSPYGHRFVTGEQGMGHVV
MAV_0593|M.avium_104 DRRVVEMIRFSDPSGNCLEVFHGVALEHRRVVSPYGHKFVTGEQGLGHVV
TH_1740|M.thermoresistible__bu DRRVVELIRFQDPSGNTLEAFHTVALEHRRVVSPYGHRFVTGEQGLGHVV
MAB_0585|M.abscessus_ATCC_1997 DRKVEAFIQFSDPSGNTLEVFHGAQYMGRRFVSPYGHKFVTAEQGLGHVV
:*:* :* * ***** * .** . **.******:*** ***:****
Mflv_1465|M.gilvum_PYR-GCK LTTRDDAETLHFYRDVLGFFLRDSMKLPPQLVGRPADGAPAWLRFLGVNP
Mvan_5306|M.vanbaalenii_PYR-1 LTTRDDAETLHFYRDVLGFYLRDSMKLPPQLVGRPADGAPAWLRFLGVNP
MSMEG_6036|M.smegmatis_MC2_155 LTTKDDRETLHFYRDILGFSLRDSMKLPPQLVGRPADGEPAWLRFLGVNP
MMAR_5063|M.marinum_M LTTRDDAEALHFYRDVLGFKLRDSMRMPPQVVGRPADGAPAWLRFFGCNP
MUL_4139|M.ulcerans_Agy99 LTTRDDAEALHFYRDVLGFKLRDSMRMPPQVVGRPADGAPAWLRFFGCNP
Mb3599c|M.bovis_AF2122/97 LSTRDDAEALHFYRDVLGFRLRDSMRLPPRMVGRPADGPPAWLRFFGCNP
Rv3568c|M.tuberculosis_H37Rv LSTRDDAEALHFYRDVLGFRLRDSMRLPPQMVGRPADGPPAWLRFFGCNP
MAV_0593|M.avium_104 LSTRDDEESLHFYRDVLGFKLRDSMRMPPQVVGRPADGAPAWLRFFGCNP
TH_1740|M.thermoresistible__bu LTTRDDAESLRFYRDVLGFYLRDSMRLPPQLVGRPADGEPAWLRFFGCNP
MAB_0585|M.abscessus_ATCC_1997 LTCTDDVAAQEFYQDVLGFQLRDSMKLPPQLVGRPADGDPVWLRFYGCNP
*: ** : .**:*:*** *****::**::******* *.**** * **
Mflv_1465|M.gilvum_PYR-GCK RHHSLAFMPGETPSGIVHLMVEVENSDDVGLCLDRALRRKVKMSATLGRH
Mvan_5306|M.vanbaalenii_PYR-1 RHHSLAFMPGETPSGIVHLMVEVENSDDVGLCLDRALRRKVKMSATLGRH
MSMEG_6036|M.smegmatis_MC2_155 RHHSLAFMPGQTPSGIVHLMVEVENSDDVGLCLDRALRRKVKMSATLGRH
MMAR_5063|M.marinum_M RHHSLAFLPLPTPSGIVHLMVEVQNSDDVGLCLDRALRRKVPMSATLGRH
MUL_4139|M.ulcerans_Agy99 RHHSLAFLPLPTPSGIVHLMVEVQNSDDVGLCLDRALRRKVPMSATLGRH
Mb3599c|M.bovis_AF2122/97 RHHSLAFLPMPTSSGIVHLMVEVEQADDVGLCLDRALRRKVPMSATLGRH
Rv3568c|M.tuberculosis_H37Rv RHHSLAFLPMPTSSGIVHLMVEVEQADDVGLCLDRALRRKVPMSATLGRH
MAV_0593|M.avium_104 RHHSLAFLPLPTPSGIVHLMLEVENADDVGLCLDRALRRKVPMSATLGRH
TH_1740|M.thermoresistible__bu RHHSLAFMPGETPSGIVHLMVEVENSDDVGLCLDRALRRKVPMSATLGRH
MAB_0585|M.abscessus_ATCC_1997 RHHALAFMPMPNPTGIVHLMVEVENSDDVGLCLDRANRRKVKMSATLGRH
***:***:* ..:******:**:::********** **** ********
Mflv_1465|M.gilvum_PYR-GCK VNDKMLSFYMKTPGGFDVEFGCEGLEVDDQNWVARESTAVSLWGHDFSVG
Mvan_5306|M.vanbaalenii_PYR-1 VNDKMLSFYMKTPGGFDIEFGCEGLEVDDENWVARESTAVSLWGHDFSVG
MSMEG_6036|M.smegmatis_MC2_155 VNDKMLSFYMKTPGGFDIEFGCEGLEVDDDNWVARESTAVSLWGHDFSVG
MMAR_5063|M.marinum_M VNDLMLSFYMKTPGGFDVEFGCEGRQVDDHDWIARESTAVSLWGHDFTVG
MUL_4139|M.ulcerans_Agy99 VNDLMLSFYMKTPGGFDVEFGCEGRQVDDHDWIARESTAVSLWGHDFTVG
Mb3599c|M.bovis_AF2122/97 VNDLMLSFYMKTPGGFDIEFGCEGRQVDDRDWIARESTAVSLWGHDFTVG
Rv3568c|M.tuberculosis_H37Rv VNDLMLSFYMKTPGGFDIEFGCEGRQVDDRDWIARESTAVSLWGHDFTVG
MAV_0593|M.avium_104 VNDLMLSFYMKTPGGFDVEFGCEGRQVEDDDWVARESTAVSLWGHDFTVG
TH_1740|M.thermoresistible__bu VNDKMLSFYMKTPGGFDVEFGCEGLQVDDEEWVARESTAVSLWGHDFSIG
MAB_0585|M.abscessus_ATCC_1997 INDKMLSFYMKTPGGFDMEFGCEGMEVDDESWVARESVGVSLWGHDFSVG
:** *************:****** :*:* .*:****..********::*
Mflv_1465|M.gilvum_PYR-GCK FK-
Mvan_5306|M.vanbaalenii_PYR-1 FKS
MSMEG_6036|M.smegmatis_MC2_155 FK-
MMAR_5063|M.marinum_M ARG
MUL_4139|M.ulcerans_Agy99 ARG
Mb3599c|M.bovis_AF2122/97 ARG
Rv3568c|M.tuberculosis_H37Rv ARG
MAV_0593|M.avium_104 MRG
TH_1740|M.thermoresistible__bu FKG
MAB_0585|M.abscessus_ATCC_1997 FK-
: