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M. thermoresistible (build 8) TH_4499 (-)

annotation: biphenyl-2,3-diol 1,2-dioxygenase 1
coordinates: 695237 - 696166
length: 310

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4499--100% (310)biphenyl-2,3-diol 1,2-dioxygenase 1
M. thermoresistible (build 8)TH_1740-7e-7949.66% (294) PROBABLE BIPHENYL-2,3-DIOL 1,2-DIOXYGENASE BPHC (23OHBP

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3599cbphC5e-7848.98% (294) putative biphenyl-2,3-diol 1,2-dioxygenase BPHC (23OHBP
M. gilvum PYR-GCKMflv_4549-1e-14279.26% (299) glyoxalase/bleomycin resistance protein/dioxygenase
M. tuberculosis H37RvRv3568cbphC5e-7848.98% (294) biphenyl-2,3-diol 1,2-dioxygenase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0076-1e-13276.01% (296) putative 2,3-dihydroxybiphenyl 1,2-dioxygenase or
M. marinum MMMAR_5063bphC5e-7647.28% (294) biphenyl-2,3-diol 1,2-dioxygenase BphC
M. avium 104MAV_3021-1e-14076.74% (301) biphenyl-2,3-diol 1,2-dioxygenase 1
M. smegmatis MC2 155MSMEG_2891-1e-15586.29% (299) biphenyl-2,3-diol 1,2-dioxygenase 1
M. ulcerans Agy99MUL_4139bphC3e-7647.28% (294) biphenyl-2,3-diol 1,2-dioxygenase BphC
M. vanbaalenii PYR-1Mvan_2891-1e-14981.13% (302) glyoxalase/bleomycin resistance protein/dioxygenase

CLUSTAL 2.0.9 multiple sequence alignment


TH_4499|M.thermoresistible__bu      MRHERDTMGFIKSLGYVIVQATDMDRWRHFAYEVLGFAEGTGPNPEALYL
MSMEG_2891|M.smegmatis_MC2_155      ---------MIKSLGYVTVQATDMQRWRHFAFGVLGFAEGKGPDPDALYL
Mflv_4549|M.gilvum_PYR-GCK          -------MSDIKSLGYVKVQATDLPRWRQFAFGVLGFAQGSGPEPDALYL
Mvan_2891|M.vanbaalenii_PYR-1       -------MSLITSLGYVTVQATDMSRWRQFAFGVLGFAEGSGPDPDAMYL
MAV_3021|M.avium_104                -------MSDLKSLGYITVSTADIERWRHFAFGVLGFAEGKGPDESALYL
MAB_0076|M.abscessus_ATCC_1997      ---------MLTSLGYLTVATRDMDRWRHFALRVLGFAEGSGPDPDALYL
Mb3599c|M.bovis_AF2122/97           --------MSIRSLGYLRIEATDMAAWREYGLKVLGMVEGKGAPEGALYL
Rv3568c|M.tuberculosis_H37Rv        --------MSIRSLGYLRIEATDMAAWREYGLKVLGMVEGKGAPEGALYL
MMAR_5063|M.marinum_M               --------MSIRSLGYLRIEATDMAAWREYGLKVLGMVEGKGSTEGALYL
MUL_4139|M.ulcerans_Agy99           --------MSIRSLGYLRIEATDMAAWREYGLKVLGMVEGKGSTEGALYL
                                              : ****: : : *:  **.:.  ***:.:*.*.   *:**

TH_4499|M.thermoresistible__bu      RMDERTARITVEPGEVDRIVTIGWEVRDHAALEDVKRALAAAGVPHRQLS
MSMEG_2891|M.smegmatis_MC2_155      RMDERCARIIVTPGDVDKIVTVGWEVRDHAALQEVKRALDAAGVPHKQLS
Mflv_4549|M.gilvum_PYR-GCK          RMDERAARIIVVPGDVDRIVTAGWEVRDRRGLEAVMRALDAAGTPFKELS
Mvan_2891|M.vanbaalenii_PYR-1       RMDERAARVVVSPGDTDKIVTVGWEVRDRAGLDEVKRALDAAGTPYKELS
MAV_3021|M.avium_104                RMDERAARIIVVPGDVDRVVTVGWEVRDHQALQRVKATLDGAGVAFKELS
MAB_0076|M.abscessus_ATCC_1997      RMDERAARVVVVPGETDQVITVGWEVRDGAALRAVVRALEAADIGVERLS
Mb3599c|M.bovis_AF2122/97           RMDDFPARLVVVPGEHDRLLEAGWECANAEGLQEIRNRLDLEGTPYKEAT
Rv3568c|M.tuberculosis_H37Rv        RMDDFPARLVVVPGEHDRLLEAGWECANAEGLQEIRNRLDLEGTPYKEAT
MMAR_5063|M.marinum_M               RMDDFPARLVIVPGTQDRLAEAGWECADAQGLQEIRNRLDVEGTPYKEAT
MUL_4139|M.ulcerans_Agy99           RMDDFPARLVIVPGTQDRLAEAGWECADAQGLQEIRNRLDVEGTPYKEAT
                                    ***:  **: : **  *::   ***  :  .*  :   *   .   .. :

TH_4499|M.thermoresistible__bu      TAEADARRVEEVVAFADPAGTALEVFHGPVLDHSPVVTPFGARFVTGDQG
MSMEG_2891|M.smegmatis_MC2_155      LAEADSRRVEEAIAFEDPAGTSLEVFHGPVLDHSPVVTPFGARFVTGDQG
Mflv_4549|M.gilvum_PYR-GCK          LAEADARRVEEVIAFEDPAGNSLEVFHGAVLDHSPVVTPYGARFVTGAQG
Mvan_2891|M.vanbaalenii_PYR-1       LADADSRRVEEVIAFEDPAGTSLEVFHGAVLDHSPVVTPFGAKFVTGEQG
MAV_3021|M.avium_104                LQEADARRVEEVITFEDPAGTTLEVFHGAVLDHSPVITPFGAKFVTGDQG
MAB_0076|M.abscessus_ATCC_1997      PEEADSRRAEEVVAFTDPAGTPVEVFHGPVLDHSPVVTPYGARFVTGAQG
Mb3599c|M.bovis_AF2122/97           AAELADRRVDEMIRFADPSGNCLEVFHGTALEHRRVVSPYGHRFVTGEQG
Rv3568c|M.tuberculosis_H37Rv        AAELADRRVDEMIRFADPSGNCLEVFHGTALEHRRVVSPYGHRFVTGEQG
MMAR_5063|M.marinum_M               AAELADRRVDEMILFSDPSGNPLAVFHGAALEHRRVVSPYGHKFVTGEQG
MUL_4139|M.ulcerans_Agy99           AAELADRRVDEMILFSDPSGNPLAVFHGAALEHRRVVSPYGHKFVTGEQG
                                      :   **.:* : * **:*. : ****..*:*  *::*:* :**** **

TH_4499|M.thermoresistible__bu      LGHVVLPTVDVDGLFEFYTEVLGFRSRGAFRVP-----APEEFGPVRVRF
MSMEG_2891|M.smegmatis_MC2_155      LGHVVLPALDVNGLFEFYTETLGFKSRGAFRVP-----VPPEFGPVRVRF
Mflv_4549|M.gilvum_PYR-GCK          LGHVVIPALDVNGLFDFYTQVLGFKSRGAFRVP-----TPPEYGPVRVRF
Mvan_2891|M.vanbaalenii_PYR-1       LGHVVLPALDVPAMFDFYTGVLGFKSRGAFRVP-----VPPEFGPVRVRF
MAV_3021|M.avium_104                LGHVVVPATDPNGLFDFYTEVLGFRSRGAFRVP-----LPAEFGPIRVRF
MAB_0076|M.abscessus_ATCC_1997      LGHVVLPVTDPEGAFTFYTEVLGFRPRGAFRIP-----APPEFGPMRVRF
Mb3599c|M.bovis_AF2122/97           MGHVVLSTRDDAEALHFYRDVLGFRLRDSMRLPPRMVGRPADGPPAWLRF
Rv3568c|M.tuberculosis_H37Rv        MGHVVLSTRDDAEALHFYRDVLGFRLRDSMRLPPQMVGRPADGPPAWLRF
MMAR_5063|M.marinum_M               LGHVVLTTRDDAEALHFYRDVLGFKLRDSMRMPPQVVGRPADGAPAWLRF
MUL_4139|M.ulcerans_Agy99           LGHVVLTTRDDAEALHFYRDVLGFKLRDSMRMPPQVVGRPADGAPAWLRF
                                    :****:.. *    : **  .***: *.::*:*      * :  *  :**

TH_4499|M.thermoresistible__bu      LGINERHHSLALCPASTLRDPGLIHLMVEVDTLDAVGQALDRVNRDGYQL
MSMEG_2891|M.smegmatis_MC2_155      LGVNERHHSLALCPASTLRDPGLVHLMVEVDSLDAVGQALDRVNADGFQL
Mflv_4549|M.gilvum_PYR-GCK          LGVNQRHHSLAICPAATVRDPKLVHLMVEVDTLDAVGQALDRVHKDGFQL
Mvan_2891|M.vanbaalenii_PYR-1       LGVNQRHHSLALCPAATLRDPGLVHLMVEVDTLDAVGQALDRVNKDGFQL
MAV_3021|M.avium_104                LGINARHHSLAICPAAQQRDPGLVHVMVEVDSLDAVGQALDRVNADGFTV
MAB_0076|M.abscessus_ATCC_1997      LGINERHHSLALCPAPHGGAPGLVHVMVEVDSLDAVGQALDRVLKDDYSL
Mb3599c|M.bovis_AF2122/97           FGCNPRHHSLAFLPMPT--SSGIVHLMVEVEQADDVGLCLDRALRRKVPM
Rv3568c|M.tuberculosis_H37Rv        FGCNPRHHSLAFLPMPT--SSGIVHLMVEVEQADDVGLCLDRALRRKVPM
MMAR_5063|M.marinum_M               FGCNPRHHSLAFLPLPT--PSGIVHLMVEVQNSDDVGLCLDRALRRKVPM
MUL_4139|M.ulcerans_Agy99           FGCNPRHHSLAFLPLPT--PSGIVHLMVEVQNSDDVGLCLDRALRRKVPM
                                    :* * ******: * .    . ::*:****:  * ** .***.      :

TH_4499|M.thermoresistible__bu      SSTLGRHTNDKMVSFYVRAPGDWDIEFGTAGMRVDETYYTAEEITADSYW
MSMEG_2891|M.smegmatis_MC2_155      SSTLGRHTNDKMVSFYVRAPGDWDIEFGTDGMRVDEQHYTAEEITADSYW
Mflv_4549|M.gilvum_PYR-GCK          SSTLGRHTNDKMVSFYVRAPGDWDIELGTEGMLVDESSYTAEEITADSYW
Mvan_2891|M.vanbaalenii_PYR-1       SSTLGRHTNDKMVSFYVRAPGDWDIEFGTDGMRVDETCYTAEEITADSYW
MAV_3021|M.avium_104                ASTLGRHTNDKMVSFYVRAPGDWDIEFGTDGMRVDETYYTAEEITADSYW
MAB_0076|M.abscessus_ATCC_1997      SSTLGRHTNDKMVSFYVRAPGGWDIEFGTDGMRVDETCYTAEEITADSYW
Mb3599c|M.bovis_AF2122/97           SATLGRHVNDLMLSFYMKTPGGFDIEFGCEGRQVDDRDWIARESTAVSLW
Rv3568c|M.tuberculosis_H37Rv        SATLGRHVNDLMLSFYMKTPGGFDIEFGCEGRQVDDRDWIARESTAVSLW
MMAR_5063|M.marinum_M               SATLGRHVNDLMLSFYMKTPGGFDVEFGCEGRQVDDHDWIARESTAVSLW
MUL_4139|M.ulcerans_Agy99           SATLGRHVNDLMLSFYMKTPGGFDVEFGCEGRQVDDHDWIARESTAVSLW
                                    ::*****.** *:***:::**.:*:*:*  *  **:  : *.* ** * *

TH_4499|M.thermoresistible__bu      GHQWVGDLPAAMRP
MSMEG_2891|M.smegmatis_MC2_155      GHQWVSDLPRAMQP
Mflv_4549|M.gilvum_PYR-GCK          GHEWVTDLPIAMQP
Mvan_2891|M.vanbaalenii_PYR-1       GHQWVDDLPAAMRP
MAV_3021|M.avium_104                GHEWIPEPPAAMRM
MAB_0076|M.abscessus_ATCC_1997      GHDWSGSQPLAAM-
Mb3599c|M.bovis_AF2122/97           GHDFTVGARG----
Rv3568c|M.tuberculosis_H37Rv        GHDFTVGARG----
MMAR_5063|M.marinum_M               GHDFTVGARG----
MUL_4139|M.ulcerans_Agy99           GHDFTVGARG----
                                    **::