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M. bovis AF2122 / 97 Mb3599c (bphC)

annotation: putative biphenyl-2,3-diol 1,2-dioxygenase BPHC (23OHBP oxygenase) (2,3-dihydroxybiphenyl dioxygenase) (2,3-dihydroxybiphenyl 1,2-dioxygenase) (DHBD)
coordinates: 3952512 - 3953414
length: 300

MSIRSLGYLRIEATDMAAWREYGLKVLGMVEGKGAPEGALYLRMDDFPARLVVVPGEHDRLLEAGWECAN
AEGLQEIRNRLDLEGTPYKEATAAELADRRVDEMIRFADPSGNCLEVFHGTALEHRRVVSPYGHRFVTGE
QGMGHVVLSTRDDAEALHFYRDVLGFRLRDSMRLPPRMVGRPADGPPAWLRFFGCNPRHHSLAFLPMPTS
SGIVHLMVEVEQADDVGLCLDRALRRKVPMSATLGRHVNDLMLSFYMKTPGGFDIEFGCEGRQVDDRDWI
ARESTAVSLWGHDFTVGARG

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3599c bphC - 100% (300) putative biphenyl-2,3-diol 1,2-dioxygenase BPHC (23OHBP oxygenase) (2,3-dihydroxybiphenyl dioxygenase) (2,3-dihydroxybiphenyl 1,2-dioxygenase) (DHBD)

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. gilvum PYR-GCK Mflv_1465 - 1e-148 82.49% (297) glyoxalase/bleomycin resistance protein/dioxygenase
M. tuberculosis H37Rv Rv3568c bphC 1e-178 99.67% (300) biphenyl-2,3-diol 1,2-dioxygenase
M. leprae Br4923 - - - - -
M. abscessus ATCC 19977 MAB_0585 - 1e-127 70.51% (295) 2,3-dihydroxybiphenyl 1,2-dioxygenase
M. marinum M MMAR_5063 bphC 1e-164 90.33% (300) biphenyl-2,3-diol 1,2-dioxygenase BphC
M. avium 104 MAV_0593 - 1e-163 89.30% (299) extradiol ring-cleavage dioxygenase
M. smegmatis MC2 155 MSMEG_6036 - 1e-145 81.82% (297) biphenyl-2,3-diol 1,2-dioxygenase
M. thermoresistible (build 8) TH_1740 - 1e-154 84.67% (300) PROBABLE BIPHENYL-2,3-DIOL 1,2-DIOXYGENASE BPHC (23OHBP
M. ulcerans Agy99 MUL_4139 bphC 1e-164 90.33% (300) biphenyl-2,3-diol 1,2-dioxygenase BphC
M. vanbaalenii PYR-1 Mvan_5306 - 1e-146 82.15% (297) glyoxalase/bleomycin resistance protein/dioxygenase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1465|M.gilvum_PYR-GCK          MT---IKSLGYLRIESTDVAAWREYGLKVLGMVEGSGPTEGALYLRMDEF
Mvan_5306|M.vanbaalenii_PYR-1       MT---IKSLGYLRIESTDVAAWREYGLKVLGMVEGSGSTEGALYLRMDEF
MSMEG_6036|M.smegmatis_MC2_155      MS---IKSLGYLRIEATDVAAWREYGLKVLGMVEGKGNTDGALYLRMDEF
Mb3599c|M.bovis_AF2122/97           MS---IRSLGYLRIEATDMAAWREYGLKVLGMVEGKGAPEGALYLRMDDF
Rv3568c|M.tuberculosis_H37Rv        MS---IRSLGYLRIEATDMAAWREYGLKVLGMVEGKGAPEGALYLRMDDF
MMAR_5063|M.marinum_M               MS---IRSLGYLRIEATDMAAWREYGLKVLGMVEGKGSTEGALYLRMDDF
MUL_4139|M.ulcerans_Agy99           MS---IRSLGYLRIEATDMAAWREYGLKVLGMVEGKGSTEGALYLRMDDF
MAV_0593|M.avium_104                MSNGAIRSLGYLRIEATDMAAWRDYGLKVLGMVEGKGDTEGALYLRMDDF
TH_1740|M.thermoresistible__bu      MS---IRSLGYLRIEATDVAAWREYGLKVLGMVEGKGPTEGALYLRMDEF
MAB_0585|M.abscessus_ATCC_1997      MS--IIKALGYMRIQATDVAAWREFGTKVLGMMEGTGDDPAALYLRMDDF
                                    *:   *::***:**::**:****::* *****:**.*   .*******:*

Mflv_1465|M.gilvum_PYR-GCK          PARLIIVPGENDRLLESGWETANAAALQDIRARLDIHGTPYKEATASQLA
Mvan_5306|M.vanbaalenii_PYR-1       PARLVIVPGERDRLLVSGWETANASQLQDIRKRLEVEGTPYKEATATQLA
MSMEG_6036|M.smegmatis_MC2_155      PARLVIVPGEHDRLQVSGWEAANAAELQDIRSRLDAAGTPFKEGTSAELA
Mb3599c|M.bovis_AF2122/97           PARLVVVPGEHDRLLEAGWECANAEGLQEIRNRLDLEGTPYKEATAAELA
Rv3568c|M.tuberculosis_H37Rv        PARLVVVPGEHDRLLEAGWECANAEGLQEIRNRLDLEGTPYKEATAAELA
MMAR_5063|M.marinum_M               PARLVIVPGTQDRLAEAGWECADAQGLQEIRNRLDVEGTPYKEATAAELA
MUL_4139|M.ulcerans_Agy99           PARLVIVPGTQDRLAEAGWECADAQGLQEIRNRLDVEGTPYKEATAAELA
MAV_0593|M.avium_104                PARLVIVPGERDHLLEAGWECANAEGLQEIRDRLDMEGVPYKEATAAQLA
TH_1740|M.thermoresistible__bu      PARLVIVPGERDRLLESGWECANAEGLQDVRSRLEAAGVPYKEGTAAELA
MAB_0585|M.abscessus_ATCC_1997      AARLVIVPGESDRLLASGWEVADAPALQAVRERLAKAGVEYAEGDKAEVS
                                    .***::***  *:*  :*** *:*  ** :* **   *. : *.  ::::

Mflv_1465|M.gilvum_PYR-GCK          DRRVDEMIIFDDPSGNTLEVFHGVALEHRRVVSPYGHKFVTEEQGLGHVV
Mvan_5306|M.vanbaalenii_PYR-1       ERRVDEMIIFDDPSGNTLEVFHGVALEHRRVVSPYGHKFVTEEQGLGHVV
MSMEG_6036|M.smegmatis_MC2_155      ERRVDEMIVFDDPSGNTLEVFHGVALEHRRVVSPYGHKFVTEEQGLGHVV
Mb3599c|M.bovis_AF2122/97           DRRVDEMIRFADPSGNCLEVFHGTALEHRRVVSPYGHRFVTGEQGMGHVV
Rv3568c|M.tuberculosis_H37Rv        DRRVDEMIRFADPSGNCLEVFHGTALEHRRVVSPYGHRFVTGEQGMGHVV
MMAR_5063|M.marinum_M               DRRVDEMILFSDPSGNPLAVFHGAALEHRRVVSPYGHKFVTGEQGLGHVV
MUL_4139|M.ulcerans_Agy99           DRRVDEMILFSDPSGNPLAVFHGAALEHRRVVSPYGHKFVTGEQGLGHVV
MAV_0593|M.avium_104                DRRVVEMIRFSDPSGNCLEVFHGVALEHRRVVSPYGHKFVTGEQGLGHVV
TH_1740|M.thermoresistible__bu      DRRVVELIRFQDPSGNTLEAFHTVALEHRRVVSPYGHRFVTGEQGLGHVV
MAB_0585|M.abscessus_ATCC_1997      DRKVEAFIQFSDPSGNTLEVFHGAQYMGRRFVSPYGHKFVTAEQGLGHVV
                                    :*:*  :* * ***** * .** .    **.******:*** ***:****

Mflv_1465|M.gilvum_PYR-GCK          LTTRDDAETLHFYRDVLGFFLRDSMKLPPQLVGRPADGAPAWLRFLGVNP
Mvan_5306|M.vanbaalenii_PYR-1       LTTRDDAETLHFYRDVLGFYLRDSMKLPPQLVGRPADGAPAWLRFLGVNP
MSMEG_6036|M.smegmatis_MC2_155      LTTKDDRETLHFYRDILGFSLRDSMKLPPQLVGRPADGEPAWLRFLGVNP
Mb3599c|M.bovis_AF2122/97           LSTRDDAEALHFYRDVLGFRLRDSMRLPPRMVGRPADGPPAWLRFFGCNP
Rv3568c|M.tuberculosis_H37Rv        LSTRDDAEALHFYRDVLGFRLRDSMRLPPQMVGRPADGPPAWLRFFGCNP
MMAR_5063|M.marinum_M               LTTRDDAEALHFYRDVLGFKLRDSMRMPPQVVGRPADGAPAWLRFFGCNP
MUL_4139|M.ulcerans_Agy99           LTTRDDAEALHFYRDVLGFKLRDSMRMPPQVVGRPADGAPAWLRFFGCNP
MAV_0593|M.avium_104                LSTRDDEESLHFYRDVLGFKLRDSMRMPPQVVGRPADGAPAWLRFFGCNP
TH_1740|M.thermoresistible__bu      LTTRDDAESLRFYRDVLGFYLRDSMRLPPQLVGRPADGEPAWLRFFGCNP
MAB_0585|M.abscessus_ATCC_1997      LTCTDDVAAQEFYQDVLGFQLRDSMKLPPQLVGRPADGDPVWLRFYGCNP
                                    *:  **  : .**:*:*** *****::**::******* *.**** * **

Mflv_1465|M.gilvum_PYR-GCK          RHHSLAFMPGETPSGIVHLMVEVENSDDVGLCLDRALRRKVKMSATLGRH
Mvan_5306|M.vanbaalenii_PYR-1       RHHSLAFMPGETPSGIVHLMVEVENSDDVGLCLDRALRRKVKMSATLGRH
MSMEG_6036|M.smegmatis_MC2_155      RHHSLAFMPGQTPSGIVHLMVEVENSDDVGLCLDRALRRKVKMSATLGRH
Mb3599c|M.bovis_AF2122/97           RHHSLAFLPMPTSSGIVHLMVEVEQADDVGLCLDRALRRKVPMSATLGRH
Rv3568c|M.tuberculosis_H37Rv        RHHSLAFLPMPTSSGIVHLMVEVEQADDVGLCLDRALRRKVPMSATLGRH
MMAR_5063|M.marinum_M               RHHSLAFLPLPTPSGIVHLMVEVQNSDDVGLCLDRALRRKVPMSATLGRH
MUL_4139|M.ulcerans_Agy99           RHHSLAFLPLPTPSGIVHLMVEVQNSDDVGLCLDRALRRKVPMSATLGRH
MAV_0593|M.avium_104                RHHSLAFLPLPTPSGIVHLMLEVENADDVGLCLDRALRRKVPMSATLGRH
TH_1740|M.thermoresistible__bu      RHHSLAFMPGETPSGIVHLMVEVENSDDVGLCLDRALRRKVPMSATLGRH
MAB_0585|M.abscessus_ATCC_1997      RHHALAFMPMPNPTGIVHLMVEVENSDDVGLCLDRANRRKVKMSATLGRH
                                    ***:***:*  ..:******:**:::********** **** ********

Mflv_1465|M.gilvum_PYR-GCK          VNDKMLSFYMKTPGGFDVEFGCEGLEVDDQNWVARESTAVSLWGHDFSVG
Mvan_5306|M.vanbaalenii_PYR-1       VNDKMLSFYMKTPGGFDIEFGCEGLEVDDENWVARESTAVSLWGHDFSVG
MSMEG_6036|M.smegmatis_MC2_155      VNDKMLSFYMKTPGGFDIEFGCEGLEVDDDNWVARESTAVSLWGHDFSVG
Mb3599c|M.bovis_AF2122/97           VNDLMLSFYMKTPGGFDIEFGCEGRQVDDRDWIARESTAVSLWGHDFTVG
Rv3568c|M.tuberculosis_H37Rv        VNDLMLSFYMKTPGGFDIEFGCEGRQVDDRDWIARESTAVSLWGHDFTVG
MMAR_5063|M.marinum_M               VNDLMLSFYMKTPGGFDVEFGCEGRQVDDHDWIARESTAVSLWGHDFTVG
MUL_4139|M.ulcerans_Agy99           VNDLMLSFYMKTPGGFDVEFGCEGRQVDDHDWIARESTAVSLWGHDFTVG
MAV_0593|M.avium_104                VNDLMLSFYMKTPGGFDVEFGCEGRQVEDDDWVARESTAVSLWGHDFTVG
TH_1740|M.thermoresistible__bu      VNDKMLSFYMKTPGGFDVEFGCEGLQVDDEEWVARESTAVSLWGHDFSIG
MAB_0585|M.abscessus_ATCC_1997      INDKMLSFYMKTPGGFDMEFGCEGMEVDDESWVARESVGVSLWGHDFSVG
                                    :** *************:****** :*:* .*:****..********::*

Mflv_1465|M.gilvum_PYR-GCK          FK-
Mvan_5306|M.vanbaalenii_PYR-1       FKS
MSMEG_6036|M.smegmatis_MC2_155      FK-
Mb3599c|M.bovis_AF2122/97           ARG
Rv3568c|M.tuberculosis_H37Rv        ARG
MMAR_5063|M.marinum_M               ARG
MUL_4139|M.ulcerans_Agy99           ARG
MAV_0593|M.avium_104                MRG
TH_1740|M.thermoresistible__bu      FKG
MAB_0585|M.abscessus_ATCC_1997      FK-
                                     :

species	id	gene	e-value	identity (len)	annotation
M. bovis AF2122 / 97	Mb3599c	bphC	-	100% (300)	putative biphenyl-2,3-diol 1,2-dioxygenase BPHC (23OHBP oxygenase) (2,3-dihydroxybiphenyl dioxygenase) (2,3-dihydroxybiphenyl 1,2-dioxygenase) (DHBD)