For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
PEFPTHRGRQTQAAIDTAARTVIARKGILATTIADIAAEAGRSAASFYNYYDSKEAMVRQWALRFRDEVN QRALSVTSHGLSNRERAYEAAAAHWNTYRNRLAEMVSVSQLAMVNEDFAQQWADMCAIPISFIKETVKRA QAEGYCPGDDPQLVAEAIVAMFNQFCYIQLSGSRTKEPDDLACIQTLANIYYRAIYGVEVS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0533 | - | - | 100% (202) | transcriptional regulatory protein |
| M. marinum M | MMAR_1492 | - | 4e-21 | 30.50% (200) | transcriptional regulatory protein |
| M. marinum M | MMAR_3762 | - | 7e-06 | 25.30% (166) | AcrR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0279c | - | 2e-93 | 80.88% (204) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_4467 | - | 1e-19 | 30.77% (195) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0273c | - | 2e-93 | 80.88% (204) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_00064 | - | 8e-05 | 21.32% (197) | putative transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4332 | - | 3e-71 | 65.99% (197) | transcriptional regulator TetR |
| M. avium 104 | MAV_4886 | - | 1e-92 | 82.65% (196) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0606 | - | 5e-75 | 66.67% (195) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0641 | - | 9e-23 | 31.96% (194) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_1197 | - | 1e-112 | 98.51% (202) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0406 | - | 2e-75 | 67.68% (198) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4467|M.gilvum_PYR-GCK ---------MPPGSSDALSAKGRQTRDALAQAARKLFAERGFHGTTLSDI
TH_0641|M.thermoresistible__bu ------------MAAETLSSKGRQTRLALEQAARKLFAERGFHGTTLADI
MMAR_0533|M.marinum_M -------------MPEFPTHRGRQTQAAIDTAARTVIARKGILATTIADI
MUL_1197|M.ulcerans_Agy99 -------------MPEFPTHRGRQTQAAIDTAARTVIARKGILATTIADI
Mb0279c|M.bovis_AF2122/97 -------------MPDFPTQRGRRTQAAIDAAARTVVVRNGILATTVADI
Rv0273c|M.tuberculosis_H37Rv -------------MPDFPTQRGRRTQAAIDAAARTVVVRNGILATTVADI
MAV_4886|M.avium_104 MSTAASPADRPGRPAALPTHRGRRTRAAIDMAARTVIARKGVLATTIADI
MSMEG_0606|M.smegmatis_MC2_155 MTVSP--------RDQLPTARGRQTQAAIDAAARAVISRKGILATTIADI
Mvan_0406|M.vanbaalenii_PYR-1 MSISP--------REELPTVRGRQTQAAIDMAARSVIARKGILATTVADI
MAB_4332|M.abscessus_ATCC_1997 --------------MVQPTVRGRQTQAAIDEAARTVIARKGILSTTVADI
MLBr_00064|M.leprae_Br4923 MINSTAGQTSQSRSRRSTRPSGDDRELAILATAEQLLEDRPLTEISVDYL
* . *: :*. :. . . :: :
Mflv_4467|M.gilvum_PYR-GCK TSAAGKSPAAFYRYFSDKEDLLAALAESFLHEVVAPSGLSVPLPESPDDD
TH_0641|M.thermoresistible__bu TSAAGKSPAVFYRYFVDKEDLLAALAESFLREVLAPGWLSVRLPDSPDDD
MMAR_0533|M.marinum_M AAEAGRSAASFYNYYDSKEAMVRQWALRFRDEVNQRALSVTSHGLS--NR
MUL_1197|M.ulcerans_Agy99 AAEAGRSAASFYNYYDSKEAMVRQWALRFRDEVNQRALSVTSHGLS--NR
Mb0279c|M.bovis_AF2122/97 TAEAGRSAASFYNYYDSKEAMVRQWALRFRDDANQRALSVIRHGLS--DR
Rv0273c|M.tuberculosis_H37Rv TAEAGRSAASFYNYYDSKEAMVRQWALRFRDDANQRALSVIRHGLS--DR
MAV_4886|M.avium_104 AAEAGRSAASFYNYYDSKEAMVRQWALRFRDEANQRARSATRHGLS--DR
MSMEG_0606|M.smegmatis_MC2_155 AAEANRSTASFYNYYDSKEAMVHEWALRFRDEARDRAQAAREPGLT--NW
Mvan_0406|M.vanbaalenii_PYR-1 AGEAGRSTASFYNYYDSKEAMVREWAVRFRDEARTRSLSAARPGLS--NW
MAB_4332|M.abscessus_ATCC_1997 AAEAGRSTASFYNYYDSKEAMVAQWAMRFRTEAQERVSAAIRHGRS--NK
MLBr_00064|M.leprae_Br4923 AKSAGISRPTFYFYFASKEAVLLTLLDRVFNKANAALETLIKNRDN-KRG
: *. * . ** *: .** :: . .. .
Mflv_4467|M.gilvum_PYR-GCK AFFTAVVTGYWTMFKQNIGIMIAVAQLAATQPRFTLVQNEFRRFGMDIVA
TH_0641|M.thermoresistible__bu EFFTTVVGGYWNMFKQNIGIMIAVDQLAATQQRFADVQNEFRRFGMDIVA
MMAR_0533|M.marinum_M ERAYEAAAAHWNTYRNRLAEMVSVSQLAMVNEDFAQQWADMCAIPISFIK
MUL_1197|M.ulcerans_Agy99 ERSYEAAAAHWNTYRNRLAEMVSVSQLAMVNEDFAQQCADMCAIPISFIK
Mb0279c|M.bovis_AF2122/97 ERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFAQYWSEICQIPISFIT
Rv0273c|M.tuberculosis_H37Rv ERAYEAAAAHWYTYRNRLAEAISVSQLAMVSDDFAQYWSEICQIPISFIT
MAV_4886|M.avium_104 DRAYTAAAAHWHTYRNRLAEVISVSQLAMVNDDFARYWAEICAIPISFIA
MSMEG_0606|M.smegmatis_MC2_155 ERSYQAVSAHWATYRHRLAEIISVSQLAMVSDDFAQYWAEICELPISLIT
Mvan_0406|M.vanbaalenii_PYR-1 ERSYQAAAAHWNTYRNRLAEIIAVSQMAMISDDFAEYWNEICSLPIALIT
MAB_4332|M.abscessus_ATCC_1997 QRARDIATAHWLTWRHQLAEMISVSQLAMINTEFAEFWNQMCSEPIDFLT
MLBr_00064|M.leprae_Br4923 NKWRTGINVFFETFG-SHKAVTCAGQVTRDNTEVRKLWSTFMQKWISYTA
.: : .. *:: . . : :
Mflv_4467|M.gilvum_PYR-GCK ASVRRAQEQGYGTELNPEHTAAAIALLFENFTTVFVGASGLG--VQMTDQ
TH_0641|M.thermoresistible__bu ASVRHAQQQGYGTDLDPQHIAAAIALMFENFTAVFVGRGGPG--LQISDA
MMAR_0533|M.marinum_M ETVKRAQAEGYCPGDDPQLVAEAIVAMFNQFCYIQLSGSRTK---EPDDL
MUL_1197|M.ulcerans_Agy99 ETVKRAQAEGYCPGDDPQLVAEAIVAMFNQFCYVQLSGSRTK---EPDDL
Mb0279c|M.bovis_AF2122/97 ETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRR-GQPDDQ
Rv0273c|M.tuberculosis_H37Rv ETVKRAQAHGYCVGDDPQLMAEAIVAMFNQFCYLQLSGKRSRR-GQPDDQ
MAV_4886|M.avium_104 ESVRRAQARGYCRDDDPQLIAEAIVAMFNQFCYIQLGSARSG---EPDDQ
MSMEG_0606|M.smegmatis_MC2_155 DMIKHAQRQGFCPDDDPHLTAVALVSMLNQFCYTKLSGGNAD---DVDDT
Mvan_0406|M.vanbaalenii_PYR-1 SLVKQAQREGFCPEDDARLVAVALVSMLNQFCYTQLSGVNADASADIDDE
MAB_4332|M.abscessus_ATCC_1997 TTIKRAQRDGYSPGNDPHLMASAIVSMMNQFAYNQLSQGNSA---TVDDD
MLBr_00064|M.leprae_Br4923 AVIDAERKRGVAPDTLPATELATALNLMNERALFASFTAEQP---HVPES
: : * . : :::: :
Mflv_4467|M.gilvum_PYR-GCK DAIATLSRIWKKTLYGY------
TH_0641|M.thermoresistible__bu DAVRTLATIWKKTLYGC------
MMAR_0533|M.marinum_M ACIQTLANIYYRAIYGVEVS---
MUL_1197|M.ulcerans_Agy99 ACIQTLANIYYRAIYGVEVS---
Mb0279c|M.bovis_AF2122/97 ACIQTLANIYYRAIYSKEDSSN-
Rv0273c|M.tuberculosis_H37Rv ACIQTLANIYYRAIYSKEDSSN-
MAV_4886|M.avium_104 ACIRTLANIYYRAIYGREEEPQS
MSMEG_0606|M.smegmatis_MC2_155 ACITTLANVFYRTIYHRGVPQP-
Mvan_0406|M.vanbaalenii_PYR-1 ACIKTLADIFYRTIYYPENGQP-
MAB_4332|M.abscessus_ATCC_1997 ACIDTLAGICYRAIYSKEVC---
MLBr_00064|M.leprae_Br4923 RVLDTLVHIWVSSIYNEIR----
: ** : ::*