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VTGALAGRAAIVTGASRGLGRAIALALAAEGAAVVVAGRTEQVWDSRLPGTIGDTVAQIEAAGGRAVAVR ADLTDRDDVATLVTGARDSLGPITILVNNAAFTAPGRPPVPGAAPRAKSSRTAVGKPGWPGFVSVPLAAY RRHFETSVFAAYELMQLSCPDMIAAGAGSIINITSVASRLPGDGPYPDRSGGVLPGYGGSKAALEHLTQC AAFDLADHHIAVNALAPSKPIPTPGLSYYAREFDDTASAEEFARAAVVLASVDADLVTGRTIGHHEVLDG SFRAFGRD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1395 | - | - | 100% (288) | short-chain type dehydrogenase/reductase |
| M. marinum M | MMAR_4581 | - | 2e-23 | 33.81% (281) | short-chain type dehydrogenase/reductase |
| M. marinum M | MMAR_1965 | fabG | 8e-22 | 35.22% (230) | short chain dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0950c | - | 2e-22 | 32.74% (281) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_4556 | - | 2e-33 | 36.33% (278) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv0927c | - | 2e-22 | 32.74% (281) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01740 | - | 4e-10 | 27.88% (226) | short chain dehydrogenase |
| M. abscessus ATCC 19977 | MAB_4632 | - | 4e-24 | 32.14% (280) | short chain dehydrogenase |
| M. avium 104 | MAV_4056 | - | 1e-127 | 75.32% (316) | oxidoreductase, short chain dehydrogenase/reductase family |
| M. smegmatis MC2 155 | MSMEG_2885 | - | 3e-33 | 36.33% (278) | short-chain dehydrogenase/reductase SDR |
| M. thermoresistible (build 8) | TH_3898 | - | 1e-25 | 35.23% (281) | PUTATIVE short chain dehydrogenase |
| M. ulcerans Agy99 | MUL_2481 | - | 1e-143 | 98.81% (253) | short-chain type dehydrogenase/reductase |
| M. vanbaalenii PYR-1 | Mvan_2884 | - | 2e-32 | 35.48% (279) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1395|M.marinum_M ---MTGALAGRAAIVTGASRGLGRAIALALAAEGAAVVVAGRTEQVWDSR
MUL_2481|M.ulcerans_Agy99 --------------------------------------MAGRTEQVWDSR
MAV_4056|M.avium_104 ---MTGRLAGRAAIVTGASRGLGRAIALALASEGAAVAVAGRTEQVWDDR
MSMEG_2885|M.smegmatis_MC2_155 ---MTNLLSGRTALVTGSSRGIGRAVAQRLAAEGAVVAVTARSYEPSPSV
Mvan_2884|M.vanbaalenii_PYR-1 ---MSGILSGKTALVTGSSRGIGRAVAQRLAAEGATVAVTARSYQPSVST
Mflv_4556|M.gilvum_PYR-GCK ---MTGLLTGRTALVTGSSRGIGRAIAQRLAAEGATVAVTARAHQPSESV
Mb0950c|M.bovis_AF2122/97 MILDMFRLDDKVAVITGGGRGLGAAIALAFAQAGADVLIASRTSS-----
Rv0927c|M.tuberculosis_H37Rv MILDMFRLDDKVAVITGGGRGLGAAIALAFAQAGADVLIASRTSS-----
TH_3898|M.thermoresistible__bu VILDRFRLDDRVAVVTGAGRGLGAAMAVAFAEAGADVLISARTQA-----
MAB_4632|M.abscessus_ATCC_1997 MILDRFKLDGNVAVVTGAGRGLGAAIAEAFAQAGADVLIASRTES-----
MLBr_01740|M.leprae_Br4923 MVKTAQYFVGKRCFVTGAASGIGRATALRLAAYGAELYLTDRHCDG----
:: *
MMAR_1395|M.marinum_M -------LPGTIGDTVAQIEAAGGRAVAV-RADLTDRDDVATLVTGARDS
MUL_2481|M.ulcerans_Agy99 -------LPGTIGDTVAQIEAAGGRAVAV-RADLTDRDDVAALVTAARDS
MAV_4056|M.avium_104 -------LPGTIGSTVADIEAAGGRAVPV-RADLTDRDDVARLVDSAREA
MSMEG_2885|M.smegmatis_MC2_155 RAGQATALPGTIGETIELIEAAGGKAFGI-AADLEDAEQRAALVDQVIER
Mvan_2884|M.vanbaalenii_PYR-1 RAGKDAELPGTIGETVELIEASGGMAFGI-ACDLEIAGQRASLVDQVVER
Mflv_4556|M.gilvum_PYR-GCK RAGVSAALPGTIDETIALIEQSGGTAFGL-AADLENSEDRAALVDRVVER
Mb0950c|M.bovis_AF2122/97 ----------ELDAVAEQIRAAGRRAHTV-AADLAHPEVTAQLAGQAVGA
Rv0927c|M.tuberculosis_H37Rv ----------ELDAVAEQIRAAGRRAHTV-AADLAHPEVTAQLAGQAVGA
TH_3898|M.thermoresistible__bu ----------QLEEVAAQIAATGRRAHVV-AADLAHPEATAELAGAAVEA
MAB_4632|M.abscessus_ATCC_1997 ----------QLREVAAKVQAAGRQAEVV-VADLSDTEASAALAQKAVDR
MLBr_01740|M.leprae_Br4923 -----------LAQTVSEARALGAQVPEYRALDISDYDEVAAFGADIHAR
: . * . *: * :
MMAR_1395|M.marinum_M LGPITILVNNAAFTAPGRPPVPGAAPRAK--------------SSRTAVG
MUL_2481|M.ulcerans_Agy99 LGPITILVNNAAFTAPGRPPVPGAAPRAK--------------SSRAAVG
MAV_4056|M.avium_104 LGPITILVNNAAFTAPGRPPAPGGEARAKPAAGGEARAKPASGGAKPASG
MSMEG_2885|M.smegmatis_MC2_155 TGRIDILVNNAGFAD-----------------------------------
Mvan_2884|M.vanbaalenii_PYR-1 TGRLDILVNNAGYAD-----------------------------------
Mflv_4556|M.gilvum_PYR-GCK TGRVDILVNNAGFAD-----------------------------------
Mb0950c|M.bovis_AF2122/97 FGKLDIVVNNVGGTMP----------------------------------
Rv0927c|M.tuberculosis_H37Rv FGKLDIVVNNVGGTMP----------------------------------
TH_3898|M.thermoresistible__bu FGKLDIVVNNVGGTMP----------------------------------
MAB_4632|M.abscessus_ATCC_1997 FGRLDVVVNNVGGTMP----------------------------------
MLBr_01740|M.leprae_Br4923 HPSMDIVMNIAGVSVWG---------------------------------
: :::* .. :
MMAR_1395|M.marinum_M ----------------KPGWPGFVSVPLAAYRRHFETSVFAAYELMQLSC
MUL_2481|M.ulcerans_Agy99 ----------------KPGWPGFVSVPLAAYRRHFETSVFAAYELMQLSC
MAV_4056|M.avium_104 GAKPASGGAKPASGGAKPGWPGFVSTPLHAYRRHFDIAVFAAYELMQRVC
MSMEG_2885|M.smegmatis_MC2_155 -------------------YSIIEDMPMDTFDRTVEHYLRTPFVLTQAAV
Mvan_2884|M.vanbaalenii_PYR-1 -------------------YSIIEDMPMETFDRTVEHYVRTPFVLTQKAV
Mflv_4556|M.gilvum_PYR-GCK -------------------YSVVADMSMATFERTVEHYVRTPFVLTQAAV
Mb0950c|M.bovis_AF2122/97 --------------------NTLLSTSTKDLADAFAFNVGTAHALTVAAV
Rv0927c|M.tuberculosis_H37Rv --------------------NTLLSTSTKDLADAFAFNVGTAHALTVAAV
TH_3898|M.thermoresistible__bu --------------------GPLLNTSAKEMRDAFTFNVGTAHALTTAAV
MAB_4632|M.abscessus_ATCC_1997 --------------------KPFLDTTNDDLAEAFSFNVLSGHALLRAAV
MLBr_01740|M.leprae_Br4923 ---------------------TVDRLTHDQWSNVVAINLMGPIHIIETFV
. . . : :
MMAR_1395|M.marinum_M PDMIA-AGAGSIINITSVASRLPGDGPYPDRSGGVLPGYGGSKAALEHLT
MUL_2481|M.ulcerans_Agy99 PDMIA-AGAGSIINITSVASRLPGDGPYPDRSGGVLPGYGGSKAALEHLT
MAV_4056|M.avium_104 PDMIG-AGGGAIINITSVASRLPGDGPYADRSGGVLPGYGGSKAALEHLT
MSMEG_2885|M.smegmatis_MC2_155 PHMRN-QGAGWIVNIGSVTGLAPVRPYREYNKSSGDVIYASMKAALHRFT
Mvan_2884|M.vanbaalenii_PYR-1 PHMRR-QGAGWIVNIGSVTGLAPARPYRDYNKTSGDVVYASMKAALHRFT
Mflv_4556|M.gilvum_PYR-GCK PHMKT-QGQGWIVNIGSVTGLAPARPYREYNKTSGDVIYASMKAALHRFT
Mb0950c|M.bovis_AF2122/97 PLMLEHSGGGSVINISSTMGRLAAR---------GFAAYGTAKAALAHYT
Rv0927c|M.tuberculosis_H37Rv PLMLEHSGGGSVINISSTMGRLAAR---------GFAAYGTAKAALAHYT
TH_3898|M.thermoresistible__bu PLMLKHSGGGSIINITSTMGRLAGR---------GFAAYGTAKAALAHYT
MAB_4632|M.abscessus_ATCC_1997 PHLLK-SDNASVINITSTMGRLPGR---------AFLGYCTAKGALAHYT
MLBr_01740|M.leprae_Br4923 PAILAAGRGGHLVNVSSAAGLVALP---------WHAAYSASKYGLRGLS
* : . ::*: *. . . * * .* :
MMAR_1395|M.marinum_M QCAAFDLADHHIAVNALAPSKPIPTPGLSYYAREFDDTASAEEFARAAVV
MUL_2481|M.ulcerans_Agy99 QCAAFDLADHHIAVNALAPSKPIPTPGLSYYAREFDDTASAEEFARAAVV
MAV_4056|M.avium_104 QCVAYDLADHRIAVNALSPSKPILTPGLSYYARDFDDTASADEFARAAVE
MSMEG_2885|M.smegmatis_MC2_155 QGVAAELLDANIAVNAVGPSSAVRTPGAASLIPDTFPTEPVEYLAETVLA
Mvan_2884|M.vanbaalenii_PYR-1 QGVAAELLDSNIAVNVVGPSSAVRTPGAASLIPDTFPTEPVEYLAETVLA
Mflv_4556|M.gilvum_PYR-GCK QGVAAELLDADIAVNAVGPSSAVRTPGAAALIPDSFPTEPVEYLAETVLA
Mb0950c|M.bovis_AF2122/97 RLAALDLCPR-VRVNAIAPGSILTSALEVVAANDELRAP----MEQATPL
Rv0927c|M.tuberculosis_H37Rv RLAALDLCPR-VRVNAIAPGSILTSALEVVAANDELRAP----MEQATPL
TH_3898|M.thermoresistible__bu RLAALDLAPR-IRVNAIAPGSILTSALDVVASNDELRTP----MEQATPL
MAB_4632|M.abscessus_ATCC_1997 RTAAMDLSPR-IRVNGIAPGSILTSALEVVAGNDEMRNT----LEQNTPL
MLBr_01740|M.leprae_Br4923 EVLRFDLARYRIGVSVVVPG-AVRTPLVDTIEIAGVDRQDPRFSRWVDRF
. :* : *. : *. : :.
MMAR_1395|M.marinum_M LASVDADLVTGRTIGHHEVLDGSFRAFGRD--------------------
MUL_2481|M.ulcerans_Agy99 LASVDADLVTGRTIGHHEVLDGSFRAFGRD--------------------
MAV_4056|M.avium_104 LALVDPGRVTGRTIGHLQVLDGSFRPSGWTRLWRLGLGSSGPHHRGGGGV
MSMEG_2885|M.smegmatis_MC2_155 MCHRPAAERTG-LVAFSLHYPWSQGLAVHSLDGRDLLPPLEPPASANPNI
Mvan_2884|M.vanbaalenii_PYR-1 MCHLPAVERTG-LVAFSLHYPWSHRLTVHSLDGTTTLPPLEPPANANPNI
Mflv_4556|M.gilvum_PYR-GCK MCHRPAAERTG-LVAFSLHYPWSQKLPVHSLDGATVLPPLEPPATANPNI
Mb0950c|M.bovis_AF2122/97 RRLGDPVDIAAAAVYLASPAGSFLTGKTLEVDGGLTFPNLDLPIPDL---
Rv0927c|M.tuberculosis_H37Rv RRLGDPVDIAAAAVYLASPAGSFLTGKTLEVDGGLTFPNLDLPIPDL---
TH_3898|M.thermoresistible__bu RRLGEPADIAAAAVYLASPAGSYLTGKVLEVDGGLTRPNLDMPIPDL---
MAB_4632|M.abscessus_ATCC_1997 HRLGDPADIAAAAVYLASPAGSFLTGKVLEVDGGLIAPNLDIPLPDLA--
MLBr_01740|M.leprae_Br4923 RGHAVSAERAAEKILAGVAKNRYLIYTSHDIRVLYGFKRLAWWPYGVVMK
. :. :
MMAR_1395|M.marinum_M --------------------------------------------------
MUL_2481|M.ulcerans_Agy99 --------------------------------------------------
MAV_4056|M.avium_104 APSPTAAHGFSDPEARQVQVRQVRPVRRADPPAPERRVRPARREVLPPPA
MSMEG_2885|M.smegmatis_MC2_155 LPAGI---------------------------------------------
Mvan_2884|M.vanbaalenii_PYR-1 LPLGL---------------------------------------------
Mflv_4556|M.gilvum_PYR-GCK LPAGL---------------------------------------------
Mb0950c|M.bovis_AF2122/97 --------------------------------------------------
Rv0927c|M.tuberculosis_H37Rv --------------------------------------------------
TH_3898|M.thermoresistible__bu --------------------------------------------------
MAB_4632|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01740|M.leprae_Br4923 QVNVVFTRALRPSPATMRCVEPIKVGVYSQPRSGEGGKSGN---------
MMAR_1395|M.marinum_M --------------------------------------------------
MUL_2481|M.ulcerans_Agy99 --------------------------------------------------
MAV_4056|M.avium_104 RREVLPPLARRVAPPRPERPALREVRAAREDRAVQVARVAAGCSAGSSPR
MSMEG_2885|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_2884|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4556|M.gilvum_PYR-GCK --------------------------------------------------
Mb0950c|M.bovis_AF2122/97 --------------------------------------------------
Rv0927c|M.tuberculosis_H37Rv --------------------------------------------------
TH_3898|M.thermoresistible__bu --------------------------------------------------
MAB_4632|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01740|M.leprae_Br4923 --------------------------------------------------
MMAR_1395|M.marinum_M -----------------------
MUL_2481|M.ulcerans_Agy99 -----------------------
MAV_4056|M.avium_104 GRLRCPASRGTRLPTRPPRRVLR
MSMEG_2885|M.smegmatis_MC2_155 -----------------------
Mvan_2884|M.vanbaalenii_PYR-1 -----------------------
Mflv_4556|M.gilvum_PYR-GCK -----------------------
Mb0950c|M.bovis_AF2122/97 -----------------------
Rv0927c|M.tuberculosis_H37Rv -----------------------
TH_3898|M.thermoresistible__bu -----------------------
MAB_4632|M.abscessus_ATCC_1997 -----------------------
MLBr_01740|M.leprae_Br4923 -----------------------