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GALDGRVALITGGARGQGRAHALALAGQGADIALADAPGPMAELTYPLGSEEDLLATAELVGQLGRRCLP MVVDVRDAAQVNTAVERTVRELGSLDIVLANAGIVSTGRLEEVSDQVWQQLMDTNLTGVFHTLRAAIPVM RQQRFGRIVATSSMGGRMGIPELAAYNATKWGIIGLIKSVALEVAKEGITANVICPTTTQTPMVQPAGIG DDQEVPDDLVRRMMKANPIPQPWLQPEDVSRGVVYLVTDPGVITGSVLEVGLGGSARMH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0924 | - | - | 100% (270) | carveol-like dehydrogenase |
| M. marinum M | MMAR_4754 | - | 3e-48 | 40.51% (274) | short-chain type dehydrogenase/reductase |
| M. marinum M | MMAR_1016 | - | 8e-43 | 38.29% (269) | short-chain dehydrogenase/reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0706 | fabG | 2e-43 | 37.59% (266) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_1589 | - | 6e-49 | 39.56% (273) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv0687 | fabG | 2e-43 | 37.59% (266) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 2e-23 | 29.81% (265) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_1408c | - | 1e-49 | 40.81% (272) | putative short-chain dehydrogenase/reductase |
| M. avium 104 | MAV_2983 | - | 7e-53 | 41.88% (277) | carveol dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_4849 | - | 8e-51 | 40.36% (275) | carveol dehydrogenase |
| M. thermoresistible (build 8) | TH_3237 | - | 6e-47 | 39.42% (274) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_0676 | - | 1e-150 | 98.89% (270) | carveol-like dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_5168 | - | 4e-49 | 39.93% (273) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0924|M.marinum_M ---------MGALDGRVALITGGARGQGRAHALALAGQGADIALADAPGP
MUL_0676|M.ulcerans_Agy99 ---------MGALDGRVALITGGARGQGRAHALALAGKGADIALADAPGP
MAB_1408c|M.abscessus_ATCC_199 ---------MADFEGKTALITGGARGMGRSHAVALAEAGADIAICDRCEN
Mflv_1589|M.gilvum_PYR-GCK --------MGGRVEGKVAFITGAARGQGRSHAVRLAEEGADIIAIDVCGP
Mvan_5168|M.vanbaalenii_PYR-1 --------MGGRVEGKVAFITGAARGQGRSHAVRLAEEGADIIAIDVCGP
TH_3237|M.thermoresistible__bu --------MAGRLEGKVAFITGAARGQGRAHAVRMAQEGADIIAVDICRQ
MSMEG_4849|M.smegmatis_MC2_155 --------MSGRVEGKVAFVTGAARGQGRSHALRLAQEGADIIAIDICGP
MAV_2983|M.avium_104 MYAGAGAVMTGRVAGKVAFISGAARGQGRSHAVRLAQEGADIIAIDICGP
Mb0706|M.bovis_AF2122/97 -----MSARGGSLHGRVAFVTGAARAQGRSHAVRLAREGADIVALDICAP
Rv0687|M.tuberculosis_H37Rv -----MSARGGSLHGRVAFVTGAARAQGRSHAVRLAREGADIVALDICAP
MLBr_01807|M.leprae_Br4923 ---------MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRL
.:.: .* .: :::: :: . .*
MMAR_0924|M.marinum_M MAE---LTYPLGSEEDLLATAELVGQLGRRCLPMVVDVRDAAQVNTAVER
MUL_0676|M.ulcerans_Agy99 MAE---LTYPLGSEEDLLATAELVGQLGRRCLPMVVDVRDPAQVNTAVER
MAB_1408c|M.abscessus_ATCC_199 SDV---VGYPLATADDLAETVALVEKTGRRCISAKVDVKDRAALESFVAE
Mflv_1589|M.gilvum_PYR-GCK ISTH--TDIPPATPDDLAQTVDLVKGTGRRIVSEQVDVRDFAAVKAAVDS
Mvan_5168|M.vanbaalenii_PYR-1 ISTH--TDIPAATPDDLAQTVDLVKGIGRRVVAAEVDVRDYAAVKAAVDS
TH_3237|M.thermoresistible__bu IDS---VQIPLASPEDLAETADLVKGLNRRIYTAEVDVRDFDALKAAVDT
MSMEG_4849|M.smegmatis_MC2_155 IRPGAETAIPASTSDDLAETANLVKGLDRRVVTAEVDVRDAAAIKAAVDS
MAV_2983|M.avium_104 IEN---LAYPHSTPEDLAETADLVKDLDRRIVTAQVDVRDFEALKSAVDS
Mb0706|M.bovis_AF2122/97 VSGS--VTYPPATSEDLGETVRAVEAEGRKVLAREVDIRDDAELRRLVAD
Rv0687|M.tuberculosis_H37Rv VSGS--VTYPPATSEDLGETVRAVEAEGRKVLAREVDIRDDAELRRLVAD
MLBr_01807|M.leprae_Br4923 VADG-----------HRVAVTHRASVVPDWFFGVECDVTDNDAIGAAFKA
. .. . *: * : .
MMAR_0924|M.marinum_M TVRELGSLDIVLANAGIVSTGR-LEEVSDQVWQQLMDTNLTGVFHTLRAA
MUL_0676|M.ulcerans_Agy99 TVRELGSLDIVLANAGIVSTGR-LEEVSDQVWQQLMDTNLTGVFHTLRAA
MAB_1408c|M.abscessus_ATCC_199 AEDTLGGIDIAITNAGISTIAL-LPEVESAQWDEVIGTNLTGTFNTIAAV
Mflv_1589|M.gilvum_PYR-GCK GVEQLGRLDIVVANAGIGNGGQTLDHTSEEDWNDMIDVNLSGVWKSVKAA
Mvan_5168|M.vanbaalenii_PYR-1 GVEQLGRLDIVVANAGIGNGGQTLDHTSEEDWNDMIDVNLSGVWKSVKAA
TH_3237|M.thermoresistible__bu GVEQLGRLDIIVANAGIGNGGETLDKTSEGDWTDMIDVNLAGVWKTVKAG
MSMEG_4849|M.smegmatis_MC2_155 GVEQLGRLDIIVANAGIGNGGDTLDQTSEEDWDEMIDINLSGVWKSVKAG
MAV_2983|M.avium_104 GVEQLGRLDIIVANAGVGTDGRKLHKIRDNVWQDMIDINLTGVWHTVKAG
Mb0706|M.bovis_AF2122/97 GVEQFGRLDIVVANAGVLGWGR-LWELTDEQWETVIGVNLTGTWRTLRAT
Rv0687|M.tuberculosis_H37Rv GVEQFGRLDIVVANAGVLGWGR-LWELTDEQWETVIGVNLTGTWRTLRAT
MLBr_01807|M.leprae_Br4923 VEEHQGPVEVLVANAGIT-SDMLIMRMSEEQFQKVIDVNLTGVFRVAKLA
* ::: ::***: : . . : ::. **:*.:.
MMAR_0924|M.marinum_M IPVMRQQ-RFGRIVATSSMGGRMGIPELAAYNATKWGIIGLIKSVALEVA
MUL_0676|M.ulcerans_Agy99 IPVMRQQ-RFGRIVATSSMGGRMGIPELAAYNATKWGIIGLIKSVALEVA
MAB_1408c|M.abscessus_ATCC_199 APGMIKR-NYGRIVTVSSMLGHSANFAQASYVSSKWGVIGLTKCAAHDLV
Mflv_1589|M.gilvum_PYR-GCK VPHLLAGGNGGSIILTSSVGGLKPYPHTGHYIAAKHGVIGLMRTFAVELG
Mvan_5168|M.vanbaalenii_PYR-1 VPHLLSGGRGGSIILTSSVGGLKPYAHTGHYIAAKHGVIGLMRTFAVELG
TH_3237|M.thermoresistible__bu VPHILAGGRGGSIILTSSVGGLKAYPHTGHYVAAKHGVVGLMRTFAVELG
MSMEG_4849|M.smegmatis_MC2_155 VPHIVAGGRGGSIVLTSSVGGLKAYPHCGNYVAAKHGVVGLMRGFAVELG
MAV_2983|M.avium_104 VPHVLSGGRGGSIVLTSSVGGRKAYPNTGHYIAAKHGVIGLMRAFAVELG
Mb0706|M.bovis_AF2122/97 VPAMIDAGNGGSIVVVSSSAGLKATPGNGHYAASKHALVALTNTLAIELG
Rv0687|M.tuberculosis_H37Rv VPAMIDAGNGGSIVVVSSSAGLKATPGNGHYAASKHALVALTNTLAIELG
MLBr_01807|M.leprae_Br4923 SRNMIKQ-RFGRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELG
: . * : .* * . * ::* .::.: . * ::
MMAR_0924|M.marinum_M KEGITANVICPTTTQTPMVQP----AGIGDDQEVP--DDLVRRMMKANPI
MUL_0676|M.ulcerans_Agy99 KEGITANVICPTTTQTPMMQP----AGIGDDQEVP--DDLVRRMMKANPI
MAB_1408c|M.abscessus_ATCC_199 GYGITVNAVAPGNIETPMTHNDFVFGTMRPDLEKPTLKDVESVFASLHLQ
Mflv_1589|M.gilvum_PYR-GCK QHSIRVNAVCPTNVNTPLFMNEGTMKLFRPDLENPGPDDLAVAAQFMHVL
Mvan_5168|M.vanbaalenii_PYR-1 QHSIRVNAVCPTNVNTPLFMNEGTMKLFRPDLENPGPDDLAVAAQFMHVL
TH_3237|M.thermoresistible__bu QHNIRVNSVHPTNVNTPLFMNEPTMKLFRPDLENPGPEDLKVVAQMMHTL
MSMEG_4849|M.smegmatis_MC2_155 QHNIRVNTVHPTHVATPMLHNEGTFKMFRPDLENPGPDDMAPICQMFHTL
MAV_2983|M.avium_104 PHMIRVNAVLPTQVSTTMVMNDQTFRLFRPDLENPGPDDFAPISQMMHTL
Mb0706|M.bovis_AF2122/97 EFGIRVNSIHPYSVDTPMIEPEAMIQTFA---KHPG---YVHSFPPMPLQ
Rv0687|M.tuberculosis_H37Rv EFGIRVNSIHPYSVDTPMIEPEAMIQTFA---KHPG---YVHSFPPMPLQ
MLBr_01807|M.leprae_Br4923 SRSITANVVAPGFIDTEMTRAMDS----------------KYQEAALQAI
* .* : * * :
MMAR_0924|M.marinum_M PQPWL-QPEDVSRGVVYLVTDPG-VITGSVLEVGLGGSARMH
MUL_0676|M.ulcerans_Agy99 PQPWL-QPEDVSRGVVYLVTDPG-VITGSVLEVGLGGSARMH
MAB_1408c|M.abscessus_ATCC_199 YAPFL-KPEEVTRAVLFLVDEASSHITGTVLPIDAGATARMI
Mflv_1589|M.gilvum_PYR-GCK PVGWV-EPRDISNAVLFLASDEARYVTGLPVTVDAGSMLK--
Mvan_5168|M.vanbaalenii_PYR-1 PVGWV-EPVDISNAVLFLASDEARYITGLPVTVDAGSMLK--
TH_3237|M.thermoresistible__bu PIGWV-EPEDIANAVLFLASDEARYITGVTLPVDGGSCLK--
MSMEG_4849|M.smegmatis_MC2_155 PIPWV-EPIDISNAVLFLASDEARYITGVTLPVDAGSCLK--
MAV_2983|M.avium_104 PVPWV-DASDISNAVLFLASDESRYVTGVSLPVDAGSLLK--
Mb0706|M.bovis_AF2122/97 PKGFM-TPDEISDVVVWLAGDGSGALSGNQIPVDKGALKY--
Rv0687|M.tuberculosis_H37Rv PKGFM-TPDEISDVVVWLAGDGSGALSGNQIPVDKGALKY--
MLBr_01807|M.leprae_Br4923 PLGRIGAVEEIAGAVSFLASEDAGYISGAVIPVDGGLGMGH-
: ::: * :*. : . ::* : :. *