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ADFEGKTALITGGARGMGRSHAVALAEAGADIAICDRCENSDVVGYPLATADDLAETVALVEKTGRRCIS AKVDVKDRAALESFVAEAEDTLGGIDIAITNAGISTIALLPEVESAQWDEVIGTNLTGTFNTIAAVAPGM IKRNYGRIVTVSSMLGHSANFAQASYVSSKWGVIGLTKCAAHDLVGYGITVNAVAPGNIETPMTHNDFVF GTMRPDLEKPTLKDVESVFASLHLQYAPFLKPEEVTRAVLFLVDEASSHITGTVLPIDAGATARMI*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1408c | - | - | 100% (277) | putative short-chain dehydrogenase/reductase |
| M. abscessus ATCC 19977 | MAB_0072c | - | 3e-52 | 39.63% (270) | putative short chain dehydrogenase/reductase |
| M. abscessus ATCC 19977 | MAB_3844c | - | 6e-52 | 43.66% (268) | putative short-chain dehydrogenase/reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0706 | fabG | 4e-46 | 38.66% (269) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_2430 | - | 4e-51 | 41.48% (270) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv0687 | fabG | 4e-46 | 38.66% (269) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 4e-27 | 29.89% (271) | 3-oxoacyl- |
| M. marinum M | MMAR_4754 | - | 2e-50 | 42.28% (272) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_3551 | - | 2e-50 | 41.54% (272) | carveol dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_6031 | - | 6e-52 | 41.24% (274) | carveol dehydrogenase |
| M. thermoresistible (build 8) | TH_3018 | - | 6e-52 | 39.71% (272) | PUTATIVE carveol dehydrogenase |
| M. ulcerans Agy99 | MUL_0676 | - | 2e-49 | 40.81% (272) | carveol-like dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_4191 | - | 2e-51 | 41.85% (270) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_1408c|M.abscessus_ATCC_199 ------MADFEGKTALITGGARGMGRSHAVALAEAGADIAICDRCENSDV
MUL_0676|M.ulcerans_Agy99 ------MGALDGRVALITGGARGQGRAHALALAGKGADIALADAPGPMAE
Mflv_2430|M.gilvum_PYR-GCK -----MAGRVEGKVAFITGAARGQGRAHAVRLAEEGADIIAVDICKQIDS
MSMEG_6031|M.smegmatis_MC2_155 -----MAGRVEGKVAFITGAARGQGRSHAVRLAEEGADIIAVDVCRRISS
MMAR_4754|M.marinum_M -MTEQLGGRVAGKVAFITGAARGQGRSHAVRLAQEGADIIAVDVCKPIVE
Mvan_4191|M.vanbaalenii_PYR-1 -----MPGRVEGKVAFVTGAARGQGRSHAIKLAEEGADIIAIDVCKNVDN
TH_3018|M.thermoresistible__bu -----MN-RLQGKVAFITGAARGQGRTHAVRLAQDGADIVAIDLCRQQPN
MAV_3551|M.avium_104 MATDDATGRVAGKRVLITGAARGMGRSHAVRLAEQGADCILVDICCTPTG
Mb0706|M.bovis_AF2122/97 --MSARGGSLHGRVAFVTGAARAQGRSHAVRLAREGADIVALDICAPVSG
Rv0687|M.tuberculosis_H37Rv --MSARGGSLHGRVAFVTGAARAQGRSHAVRLAREGADIVALDICAPVSG
MLBr_01807|M.leprae_Br4923 ------MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARR----
.: .* .: :::: :: . .
MAB_1408c|M.abscessus_ATCC_199 -VGYPLATADDLAETVALVEKTGRRCISAKVDVKDRAALESFVAEAEDTL
MUL_0676|M.ulcerans_Agy99 -LTYPLGSEEDLLATAELVGQLGRRCLPMVVDVRDPAQVNTAVERTVREL
Mflv_2430|M.gilvum_PYR-GCK -VLIPLSTPEDLAETADLVKNAGGRIHTAEVDVRDYDALKAAVDAGVEEF
MSMEG_6031|M.smegmatis_MC2_155 NEDIPASTPEDLAETVELVKGLNRRIVAEEVDVRDYDALKAVVDSGVEQL
MMAR_4754|M.marinum_M NTTIPASTPEDLAETADLVKGHNRRIFTAEADVRDYDALKAAVDAGVDEL
Mvan_4191|M.vanbaalenii_PYR-1 -VQLDLATPGDLLETKARVEALGRRIIAEEVDVRDYDAMKAVVDRGVAEL
TH_3018|M.thermoresistible__bu -LDYAQGSPEELKETVRLVEEQGRRIIARQADVRDLASLQAVVDEALAEF
MAV_3551|M.avium_104 -LDYPLATEEDLNETVRLVEKHGRRAVPKIVDVRDEAAMKAAVDAAVDEL
Mb0706|M.bovis_AF2122/97 SVTYPPATSEDLGETVRAVEAEGRKVLAREVDIRDDAELRRLVADGVEQF
Rv0687|M.tuberculosis_H37Rv SVTYPPATSEDLGETVRAVEAEGRKVLAREVDIRDDAELRRLVADGVEQF
MLBr_01807|M.leprae_Br4923 -----LVADGHRVAVTHRASVVPDWFFGVECDVTDNDAIGAAFKAVEEHQ
: . . . *: * : .
MAB_1408c|M.abscessus_ATCC_199 GGIDIAITNAGISTIALLPEVESAQ-WDEVIGTNLTGTFNTIAAVAPGMI
MUL_0676|M.ulcerans_Agy99 GSLDIVLANAGIVSTGRLEEVSDQV-WQQLMDTNLTGVFHTLRAAIPVMR
Mflv_2430|M.gilvum_PYR-GCK GRLDIIVANAGIGNGGQTLDKTDEPDWDDMIGVNLSGVWKTVKAGVPHIL
MSMEG_6031|M.smegmatis_MC2_155 GGLDIVVANAGIGNGGATLDKTSEADWDDMIGVNLSGVWKTVKAAVPHLI
MMAR_4754|M.marinum_M GRLDIIVANAGIGNGGATLDKTSEHDWQEMIDVNLSGVWKSVKAAVPHLI
Mvan_4191|M.vanbaalenii_PYR-1 GRLDIILANAGIGNGGQTVETLEEDVWQTMMDVNLTGVWKTVKAGIPHMI
TH_3018|M.thermoresistible__bu GHIDILVSNVGISNQGEVVSLTDQQ-WSDILQTNLIGAWHACRAVLPSMI
MAV_3551|M.avium_104 GGLDGAVANAGVLTVG-TWDTTTAEQWRLVLDVNLIGAWNTCAAALPHLI
Mb0706|M.bovis_AF2122/97 GRLDIVVANAGVLGWGRLWELTDEQ-WETVIGVNLTGTWRTLRATVPAMI
Rv0687|M.tuberculosis_H37Rv GRLDIVVANAGVLGWGRLWELTDEQ-WETVIGVNLTGTWRTLRATVPAMI
MLBr_01807|M.leprae_Br4923 GPVEVLVANAGITSDMLIMRMSEEQ-FQKVIDVNLTGVFRVAKLASRNMI
* :: ::*.*: : :: .** *.:. :
MAB_1408c|M.abscessus_ATCC_199 KRN-YGRIVTVSSMLGHSANFAQASYVSSKWGVIGLTKCAAHDLVGYGIT
MUL_0676|M.ulcerans_Agy99 QQR-FGRIVATSSMGGRMGIPELAAYNATKWGIIGLIKSVALEVAKEGIT
Mflv_2430|M.gilvum_PYR-GCK AGGNGGSIILTSSVGGLKAYPHTGHYVAAKHGVVGLMRTFAVELGAQNIR
MSMEG_6031|M.smegmatis_MC2_155 SGGNGGSIILTSSVGGLKAYPHTGHYIAAKHGVVGLMRTFAVELGQHSIR
MMAR_4754|M.marinum_M AGGNGGSIVLTSSVGGMKAYPHCGNYVAAKHGVVGLMRSFAVELGQHMIR
Mvan_4191|M.vanbaalenii_PYR-1 AGGRGGSIVLTSSVAGLKAYPQMSQYVSAKHGVVGLMRSCATELGQHMIR
TH_3018|M.thermoresistible__bu ERGQGGSVIFVSSTVGLRGAPGQSHYAASKHGVQGLMLSLANEVGRHNIR
MAV_3551|M.avium_104 GGG-GGSLVNISSSAGIKGTPLHLPYTASKHGIVGMTLALANELAAQNIR
Mb0706|M.bovis_AF2122/97 DAGNGGSIVVVSSSAGLKATPGNGHYAASKHALVALTNTLAIELGEFGIR
Rv0687|M.tuberculosis_H37Rv DAGNGGSIVVVSSSAGLKATPGNGHYAASKHALVALTNTLAIELGEFGIR
MLBr_01807|M.leprae_Br4923 KQR-FGRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSIT
* : .* * . * ::* .: .: * :: *
MAB_1408c|M.abscessus_ATCC_199 VNAVAPGNIETPMTHNDFVFGTMRPDLEKPTLKDVESVFASLHLQYAPFL
MUL_0676|M.ulcerans_Agy99 ANVICPTTTQTPMMQP----AGIGDDQEVP--DDLVRRMMKANPIPQPWL
Mflv_2430|M.gilvum_PYR-GCK VNSVHPTNVNTPLFMNEPTMKLFRPDLENPGPDDMKVVGQLMHTLPIGWV
MSMEG_6031|M.smegmatis_MC2_155 VNSVHPTNVNTPLFMNEGTMKLFRPDLENPGPDDMAVVAQMMHVLPVGWV
MMAR_4754|M.marinum_M VNSVHPTHVRTPMLHNEGTFKMFRPDLENPGPDDMAPICQLFHTLPIPWV
Mvan_4191|M.vanbaalenii_PYR-1 VDSVHPTHVNSPMVMNDETFRMFRPDLENPGPDDIAPICQMFHTMPRPWV
TH_3018|M.thermoresistible__bu VNSVNPGAVNTEMALNEKLLKMFLPHLENPTREDAAELFSQLTLLPIPWV
MAV_3551|M.avium_104 VNTVHPTGVATGMAPPG-----MHALIAEQRPD---LVPIFLNALPAPLI
Mb0706|M.bovis_AF2122/97 VNSIHPYSVDTPMIEPEAMIQTFAKHPG------YVHSFPPMPLQPKGFM
Rv0687|M.tuberculosis_H37Rv VNSIHPYSVDTPMIEPEAMIQTFAKHPG------YVHSFPPMPLQPKGFM
MLBr_01807|M.leprae_Br4923 ANVVAPGFIDTEMTRAMDS----------------KYQEAALQAIPLGRI
.: : * : : :
MAB_1408c|M.abscessus_ATCC_199 -KPEEVTRAVLFLVDEASSHITGTVLPIDAGATARMI
MUL_0676|M.ulcerans_Agy99 -QPEDVSRGVVYLVTDPG-VITGSVLEVGLGGSARMH
Mflv_2430|M.gilvum_PYR-GCK -EPEDIANAVLFLASDEARFITGVTLPVDGGSCLK--
MSMEG_6031|M.smegmatis_MC2_155 -EPRDISNAVLFLASDEARYVTGLPMTVDAGSMLK--
MMAR_4754|M.marinum_M -EAEDISNAVLFLASDESRYITGVTLPVDAGGCLK--
Mvan_4191|M.vanbaalenii_PYR-1 -EVEDITNAVMFFASDDSRYVTGVAMPIDLGSCLK--
TH_3018|M.thermoresistible__bu -EPEDVSNAVAWLASDEARYIHGAAIPVDGGQLARA-
MAV_3551|M.avium_104 -EASDVSNAVLYLISDESRYVTGLELKVDAGVTIR--
Mb0706|M.bovis_AF2122/97 -TPDEISDVVVWLAGDGSGALSGNQIPVDKGALKY--
Rv0687|M.tuberculosis_H37Rv -TPDEISDVVVWLAGDGSGALSGNQIPVDKGALKY--
MLBr_01807|M.leprae_Br4923 GAVEEIAGAVSFLASEDAGYISGAVIPVDGGLGMGH-
::: * :: : . : * : :. *