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YSISALLDALDAAVAAIGEADLGHLEPAARLRALQRLENARRRQAVVSHDVIAGLATEDLADIGGPVYKV VADWLRISCAEARRRVHDAQQLSPRITLTGQPLPAELPATAQVWRRGLLDGQHVKVIAAFVRDLPQDTPA DTVRQAEQFLARQAVQLRPDQLEKVANRAAVLINPDGKFSDADRARQRGFTWCAQRPDGMSIGKLIATPQ LRAHLDAWLARFAAPGMCNPDDETPCVKGEPTDEVTAKDLRSPAQRRHDALNALLDGRLGDPKLGAHNGL PVTVIVSTTLRELTSGTGRAVTGGGTFVPMRDVIRMASRAYHYLAVFDEHSNRPLYLGRSRRLASADQRL VLYAQDRGCTHPGCDVPGYWCEVHHTDEWAAGGPTDVDKLTFACKPDHKLAGNGWQTTKLPNGRTAWIPP PQLDRGARTNDYHHPERLFDDEGP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1937 | - | - | 100% (445) | hypothetical protein MMAR_1937 |
| M. marinum M | MMAR_0868 | - | 0.0 | 77.60% (442) | hypothetical protein MMAR_0868 |
| M. marinum M | MMAR_1523 | - | e-116 | 50.57% (441) | hypothetical protein MMAR_1523 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1179c | - | 1e-108 | 47.22% (449) | hypothetical protein Mb1179c |
| M. gilvum PYR-GCK | Mflv_4397 | - | 2e-88 | 44.94% (445) | hypothetical protein Mflv_4397 |
| M. tuberculosis H37Rv | Rv1128c | - | 1e-108 | 47.52% (444) | hypothetical protein Rv1128c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0394c | - | 1e-116 | 49.66% (439) | hypothetical protein MAB_0394c |
| M. avium 104 | MAV_3664 | - | 0.0 | 74.43% (442) | hypothetical protein MAV_3664 |
| M. smegmatis MC2 155 | MSMEG_6573 | - | 3e-82 | 40.82% (441) | hypothetical protein MSMEG_6573 |
| M. thermoresistible (build 8) | TH_3287 | - | 8e-74 | 39.71% (481) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2371 | - | 1e-114 | 49.33% (450) | hypothetical protein MUL_2371 |
| M. vanbaalenii PYR-1 | Mvan_3050 | - | 1e-96 | 43.48% (483) | hypothetical protein Mvan_3050 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1179c|M.bovis_AF2122/97 MSETFCLTDHSEPMTARFLSVVLRRIRGMRSDTREEISAALDAYHASLSR
Rv1128c|M.tuberculosis_H37Rv -----------------------------MCSTREEITEAFASLATALSR
MUL_2371|M.ulcerans_Agy99 -------------------------MHSNGCSDRESVVATLDRLDRAVDA
MAB_0394c|M.abscessus_ATCC_199 -------------------------------------MSPIDDLLTTATA
MMAR_1937|M.marinum_M ---------------------------MYSIS------ALLDALDAAVAA
MAV_3664|M.avium_104 ---------------------------MHSIEVPAEVRAALDALDTADAA
TH_3287|M.thermoresistible__bu ----------------------MGQQFVTAGAARARVGELLAAVDAAYAE
Mvan_3050|M.vanbaalenii_PYR-1 -----------------------------MGCSREDVLGAFDALDAVVES
Mflv_4397|M.gilvum_PYR-GCK -------------------------------MSGGDLQTSIAALRAAFEE
MSMEG_6573|M.smegmatis_MC2_155 -------------------------------MDDG-VQDAVAALDAALNT
.
Mb1179c|M.bovis_AF2122/97 VLDLKCDALTTPELLACLQRLEVERRRQGAAEHALINQLAGQACEEELGG
Rv1128c|M.tuberculosis_H37Rv VLGLTFDALTTPERLALLEHCETARRQLPSVEHTLINQIGEQSTEEELGG
MUL_2371|M.ulcerans_Agy99 LVEVSFEALTTPERLRVLERLEVVARRLPAAQYALVNQLDEQPGEAELGG
MAB_0394c|M.abscessus_ATCC_199 VVESSFDELNNPELLSALRQLEIAQRKITAASHTLTARLVQRGSPVALGG
MMAR_1937|M.marinum_M IGEADLGHLEPAARLRALQRLENARRRQAVVSHDVIAGLATE-DLADIGG
MAV_3664|M.avium_104 IRALDFDALHPVVRLRALERMEASRRRQIAVSHDVIAGLAGE-GPANVGG
TH_3287|M.thermoresistible__bu MRALCLDEVGTGFRLELAERLETQCRINRGLMYRVFAQLADPPDEPAMVP
Mvan_3050|M.vanbaalenii_PYR-1 ILALDYDALSAAERVRLEARLERNLRRIPTVEHELLASVIAETEPARLGE
Mflv_4397|M.gilvum_PYR-GCK VAAADVDLLTRPDLVAALDELEELSCQLPAVGHRLLARLQVETSAREMGA
MSMEG_6573|M.smegmatis_MC2_155 LLTLPHSALTDAELLTICAGLQDARNRIPAVEHRAIAALSQQTTPAAIGA
: : : : : : :
Mb1179c|M.bovis_AF2122/97 T-LRTALANRLHITPGEASRRIAEAEDLGERRALTGEPLPAQLTATAAAQ
Rv1128c|M.tuberculosis_H37Rv K-LGLTLADRLRITRSEAKRRVAEAADLGQRRALTGEPLPPLLTATAKAQ
MUL_2371|M.ulcerans_Agy99 R-LAAVVASRLRITRSEAGRRVAEAAEVGPRRALSGQPVGPVLTATAAAL
MAB_0394c|M.abscessus_ATCC_199 TSFAEVLARYLSITTATARRRLADAAHLGPRRALTGEPLRPALPYVAHAL
MMAR_1937|M.marinum_M P-VYKVVADWLRISCAEARRRVHDAQQLSPRITLTGQPLPAELPATAQVW
MAV_3664|M.avium_104 P-VHKVIADRLRISYAEACRRLREAKQLSPRLTLTGQELPPELPATAGVW
TH_3287|M.thermoresistible__bu A-VRDRLWARLRITPGEVKRRLRVAALLRPRRRLSGPPLPPVLARVAGAV
Mvan_3050|M.vanbaalenii_PYR-1 GSWKKVLTTALRISGAEAGRRLKRAKTLGPRRGLTGTPLPPLWESTAAAQ
Mflv_4397|M.gilvum_PYR-GCK KSWNQVLAVRWRISTGEAHRRLTEAALLAPRQSLTGTPLPPALPATAVAQ
MSMEG_6573|M.smegmatis_MC2_155 KSWPLVLATRLGISSKEARRRCTDAAELGPRVSMTGEALAPKREHIAAAQ
: *: . ** * : * ::* : . * .
Mb1179c|M.bovis_AF2122/97 REGKIGREHIKEIQAFFKELSAAVDLGIREAAEAQLAELATSRRPDHLHG
Rv1128c|M.tuberculosis_H37Rv RHGLIGDGHVEVIRAFVHRLPSWVDLKTLEKAERDLAKQATQYRPDQLAK
MUL_2371|M.ulcerans_Agy99 RQGVVGEGHVRVIRDFFRQLPAGVDVGTRDRAEAHLAKLATQFRPDQLAR
MAB_0394c|M.abscessus_ATCC_199 REGRLGDEHVRIIRRFFDVLPDAVDADTREAAEKQLASMGTEFGPEQLRA
MMAR_1937|M.marinum_M RRGLLDGQHVKVIAAFVRDLPQDTPADTVRQAEQFLARQAVQLRPDQLEK
MAV_3664|M.avium_104 REGMLDGQHLRVIEKFVRDLPETTPVRALEEAERFLAHQATLLRPDQLEK
TH_3287|M.thermoresistible__bu ESGLLGEEHLRVITTVMAALPSAVSVTDREAVEASLIAEAARSDAGIVRQ
Mvan_3050|M.vanbaalenii_PYR-1 AQGLLSEEHVAVIAAFHKRLPAWVDIETRAEADRQLAHAGSGLDPEGLDE
Mflv_4397|M.gilvum_PYR-GCK SRGLINAEHVEVIRKAVKKLPGWVDVATREQFEVNLVRTAVGNGPKELRD
MSMEG_6573|M.smegmatis_MC2_155 ADGTLTPDHVAELFKFFTKCPDWVTYAEQCRLEEKLVTGAIGADPETVRQ
* : *: : . . : * . . :
Mb1179c|M.bovis_AF2122/97 LATQLMDWLHPDG-NFSDQERARKRGITMGKQEFDGMSRISGLLTPELRA
Rv1128c|M.tuberculosis_H37Rv LAARIMDCLNPDG-DYTDEDRARRRGLTLGKQDVDGMSRLSGYVTPELRA
MUL_2371|M.ulcerans_Agy99 LAGRLMDCLNPDG-RHSDEDRARRRGLSLGRQGLDGMSRISGWLTPEARA
MAB_0394c|M.abscessus_ATCC_199 GADRIAALVNPDG-RFSDIDRARRRGISIGRQGADGMSALSGLLDPETRA
MMAR_1937|M.marinum_M VANRAAVLINPDG-KFSDADRARQRGFTWCAQRPDGMSIGKLIATPQLRA
MAV_3664|M.avium_104 VAHQCALRINPDG-KFSDADRARQRGFTWCGQRADEMSLGKLWASPELRA
TH_3287|M.thermoresistible__bu VGRRIEEIFNPDG-HYDDQDRARRRGIHLGDQQRDGMSAISGWIDPQLRA
Mvan_3050|M.vanbaalenii_PYR-1 AAGVLLAMINPDGAQPCDKERARKRGIRISKQHPDGTATISGTLTPEALA
Mflv_4397|M.gilvum_PYR-GCK AAELTLFLLDQDGPEPDDTERARKRGLTKGKQRPDGMIDLAGTLTPEAWA
MSMEG_6573|M.smegmatis_MC2_155 AVDHAVFLLDQDGPAPTDNPPTKPFGITFGPQQPDGSYHLRGKVSAEFKA
.. ** * :: *: * * .: *
Mb1179c|M.bovis_AF2122/97 TIEAVLAKLAAPGACNPDD-----------------------QTPLVDDT
Rv1128c|M.tuberculosis_H37Rv TIEAVWAKLAAPGMCNPEQ-----------------------KAPCVNGA
MUL_2371|M.ulcerans_Agy99 GLEAVWAKLAAPGMCNPED-----------------------EAAVVDGP
MAB_0394c|M.abscessus_ATCC_199 YFDAVLSKLAAPGMCDPRD-----------------------ESPMTEGE
MMAR_1937|M.marinum_M HLDAWLARFAAPGMCNPDD-----------------------ETPCVKGE
MAV_3664|M.avium_104 NLDAWLARFAAPGMCNPDD-----------------------EVPCVAGE
TH_3287|M.thermoresistible__bu YLEAVTAAVR-PGRHLPHTTTDTTGTTG------------TTETTGTAGT
Mvan_3050|M.vanbaalenii_PYR-1 IWQAIFAKEAAPGANNPESEHTEDSTSGGAADDASDAPGDHAGAASSAAS
Mflv_4397|M.gilvum_PYR-GCK VLEVIFAKYAAPGMCNPAD-----------------------PEPCTYGT
MSMEG_6573|M.smegmatis_MC2_155 TFDPIDEKLAAPGMCNPTD-----------------------QTPCISGT
: ** * .
Mb1179c|M.bovis_AF2122/97 PDADAVRRD---------------TRSQAQRNHDAFLAALRGLLASGELG
Rv1128c|M.tuberculosis_H37Rv PSKEQARRD---------------TRSCPQRNHDALNAELRSLLTSGNLG
MUL_2371|M.ulcerans_Agy99 VSRDAADRD---------------SRSVSQRQHDGFNAALRAVLASGELG
MAB_0394c|M.abscessus_ATCC_199 PDSAAAERD---------------TRTSAQRNHDGLRACLRSTLASGKLG
MMAR_1937|M.marinum_M PTDEVTAKD---------------LRSPAQRRHDALNALLDGRLGDPKLG
MAV_3664|M.avium_104 PDEESATKD---------------SRTPAQRQHDALNALVRGRLGDPKLG
TH_3287|M.thermoresistible__bu AGTAATAADTAADGVGDIDTGGVDLRSAAQRRHDGLTLGLKIAVASGRLG
Mvan_3050|M.vanbaalenii_PYR-1 GASDAAEHDPQPERCG------SDTRTQAQRNHDAFLAVGRRLLESGELG
Mflv_4397|M.gilvum_PYR-GCK PTQAQIDND---------------QRSLAQRQHDALVAVGRIALMSGELG
MSMEG_6573|M.smegmatis_MC2_155 PSQQQIDSD---------------QRGAPERRHDAMLTAMRLLLAHKDLG
* * .:*.**.: : **
Mb1179c|M.bovis_AF2122/97 QHKGLPVTIVVSTTLKELEAAT-----------GKGVTGGGSRVPMSDLI
Rv1128c|M.tuberculosis_H37Rv QHNGLPASIIVTTTLKDLEAAA-----------GAGLTGGGTILPISDVI
MUL_2371|M.ulcerans_Agy99 QHNGLPASIIVSTTLKELEAAA-----------GRGLTGGGTLLPMSDVI
MAB_0394c|M.abscessus_ATCC_199 AHRGLPVTVVVSTTLRELQSAA-----------GRAISGSGNLVPIPDLI
MMAR_1937|M.marinum_M AHNGLPVTVIVSTTLRELTSGT-----------GRAVTGGGTFVPMRDVI
MAV_3664|M.avium_104 LHNGLPVTVIVSTTLRELTTGA-----------GRAVTGGGTLLPMRDVI
TH_3287|M.thermoresistible__bu SHRGHPVTVIVRTTLGELNQAAHAVADPRVSMPGPARTGGTGVLPMRELI
Mvan_3050|M.vanbaalenii_PYR-1 THNGLPVTVIVSTTLQELEKGA-----------GVAVTGGGSLLPMPDLI
Mflv_4397|M.gilvum_PYR-GCK QLNGLPVSIIIRTTLQDLESRA-----------GVGTTGGGTVVPIKDVI
MSMEG_6573|M.smegmatis_MC2_155 QINGLPATLLVTTTLQELEKAA-----------GVAITAGGTKLSIPDLI
.* *.:::: *** :* : * . :.. :.: ::*
Mb1179c|M.bovis_AF2122/97 RMASHANHYLALF--DGAKPLALYHTKRLASPAQRIMLYAKDRGCSRPGC
Rv1128c|M.tuberculosis_H37Rv RLARHANHYLAIF--DRGKALALYHTKRLASPAQRIMLYAKDSGCSAPGC
MUL_2371|M.ulcerans_Agy99 RLARHAHHYLAVF--DRGEAIGLYHAKRLATPGQRIVLYAKDRGCTRPGC
MAB_0394c|M.abscessus_ATCC_199 RMATHAFHYLTIFG-DDGRPLHLGRSKRIATPDQRIVLHAKDRGCSAPGC
MMAR_1937|M.marinum_M RMASRAYHYLAVFDEHSNRPLYLGRSRRLASADQRLVLYAQDRGCTHPGC
MAV_3664|M.avium_104 RMARHAYHYLAVFDEHSSRPLYLGRSRRVASPDQRVVLYAKDRGCTHPGC
TH_3287|M.thermoresistible__bu RMAADAIHYLAVFDDHTERPLYLGRQKRIATADQRLICYARDGGCTAPGC
Mvan_3050|M.vanbaalenii_PYR-1 RLAARAHHYLYVYDQHSGKSLYLGRAKRLANAAQRIVLHARDRGCTRPGC
Mflv_4397|M.gilvum_PYR-GCK RMAGHANHYLAVFDRATGSALDLFRTRRVASPAQRVMLIARDGGCTKPCC
MSMEG_6573|M.smegmatis_MC2_155 RLASQALHYLAVYDEHTGIPLYLGRARRTASAGQRLAIWARDRGCTRPGC
*:* * *** :: .: * : :* *.. **: *:* **: * *
Mb1179c|M.bovis_AF2122/97 DAPAYHSEVHHVTP-WTTTHRTDINDLTLACGPDNR-LVEKG--WKTRKN
Rv1128c|M.tuberculosis_H37Rv DVPGYYCEVHHVTP-YAQCRNTDVNDLTLGCGGHHP-LAERG--WTTRKN
MUL_2371|M.ulcerans_Agy99 DVAGYQCEVHHVAA-WAISGRTDINQLTLACGPDHK-LLEQG--WRTRKN
MAB_0394c|M.abscessus_ATCC_199 TVPGYLCQVHHVDD-WRDDGPTDIDNLTFACGPHHR-LLQQG--WTTRKR
MMAR_1937|M.marinum_M DVPGYWCEVHHTDE-WAAGGPTDVDKLTFACKPDHK-LAGNG--WQTTKL
MAV_3664|M.avium_104 DAPGYWCEVHHLDE-WATGGLTDVDNLTFACGTHHK-LIENG--WRTNKL
TH_3287|M.thermoresistible__bu GEPGYHAETHHQPA-WEDGGLTDADHLFFACGPHHSGLTEGR--WQATIT
Mvan_3050|M.vanbaalenii_PYR-1 TAPGYWCQAHHASADFVDGGLTNIDDLTLACPCDHRMLDNTG--WRTRKN
Mflv_4397|M.gilvum_PYR-GCK TVGAYGCQVHHAETDYAHGGNTNIDELGLACGPDNRSVTEGG--WTTRIN
MSMEG_6573|M.smegmatis_MC2_155 TANGYRCQAHHATTDYAKGGLTDADALALACGCDNRLVGEAPNKWTTRIN
.* .:.** : *: : * :.* .: : * :
Mb1179c|M.bovis_AF2122/97 -AHGDTEWLPPPHLDHGQPRINRYHHPAKILCEQ----------------
Rv1128c|M.tuberculosis_H37Rv -AHGDTEWLPPPHLDHGQPRVNTFHHPEKLLAD-----------------
MUL_2371|M.ulcerans_Agy99 -AHGDTEWLPPPHLDHGQPRTNSYHHPEKLLRDS----------------
MAB_0394c|M.abscessus_ATCC_199 RSDGITEWIPPPHLDTGQSRTNDHHHPERFIRRF----------------
MMAR_1937|M.marinum_M -PNGRTAWIPPPQLDRG-ARTNDYHHPERLFDD-----------------
MAV_3664|M.avium_104 -ADGRTAWIPPPQWDRG-ARTNEFHHPERAFDG-----------------
TH_3287|M.thermoresistible__bu -PTGRLAWTND---HHP-PTVNHAHHPEELLRAH----------------
Mvan_3050|M.vanbaalenii_PYR-1 -GKNQTEWLPPPDLDTGQHRVNGHHHPERYLLPE----------------
Mflv_4397|M.gilvum_PYR-GCK -DRCEVEWIPPPGLDTGQARVNTYHRPERLLAPP----------------
MSMEG_6573|M.smegmatis_MC2_155 -NHGQCEWIPPDLLDRGQHRTNTYHHPETLLADINRDQKTDGDNREQHHT
* . * *:* :
Mb1179c|M.bovis_AF2122/97 -----------DDDEPH---------------------------------
Rv1128c|M.tuberculosis_H37Rv -----------DEGDP----------------------------------
MUL_2371|M.ulcerans_Agy99 -----------ADDDDEGHGAA----------------------------
MAB_0394c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1937|M.marinum_M ---------------EGP--------------------------------
MAV_3664|M.avium_104 ---------------EDP--------------------------------
TH_3287|M.thermoresistible__bu -----------TDPPEDPG-------------------------------
Mvan_3050|M.vanbaalenii_PYR-1 -----------DDLPEDDQGP-----------------------------
Mflv_4397|M.gilvum_PYR-GCK ---------------DDPEPP------NQTRTTATEPVEDQAIDDPETDA
MSMEG_6573|M.smegmatis_MC2_155 DTGADTGTVHVNGHGEKPAIPPELLDQGQQRTAPYHQAEVPPVNTRDTRS
Mb1179c|M.bovis_AF2122/97 -------------------------------------
Rv1128c|M.tuberculosis_H37Rv -------------------------------------
MUL_2371|M.ulcerans_Agy99 -------------------------------------
MAB_0394c|M.abscessus_ATCC_199 -------------------------------------
MMAR_1937|M.marinum_M -------------------------------------
MAV_3664|M.avium_104 -------------------------------------
TH_3287|M.thermoresistible__bu -------------------------------------
Mvan_3050|M.vanbaalenii_PYR-1 -------------------------------------
Mflv_4397|M.gilvum_PYR-GCK PPPLDDPGEPGGP----------APPDNRAA------
MSMEG_6573|M.smegmatis_MC2_155 STTTRDANRHNGNGDRNSAENRNGPSKNAAGDDDEPR