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MTDGSVTADKLQKWFREYLSTHIECHPNEVSLDVPIRDLGLKSIDVLAIPGDLGDRFGFCIPDLAVWDNP SANDLIDSLLNQRSADSLRESHGHADRNTQGRGSINEPVAVIGVGCRFPGDIDGPERLWDFLTEKKCAIT AYPDRGFTNAGTFAESGGFLKDVAGFDNRFFDIPPDEALRMDPQQRLLLEVSWEALEHAGIIPESLRLSR TGVFVGVSSTDYVRLVSASAQQKSTIWDNTGGSSSIIANRISYFLDIQGPSIVIDTACSSSLVAVHLACR SLSTWDCDIALVGGTNVLISPEPWGGFREAGILSQTGCCHAFDKSADGMVRGEGCGVIVLQRLSDARLEG RRILAILTGSAVNQDGKSNGIMAPNPSAQIGVLENACKSARVDPLEIGYVEAHGTGTSLGDRIEAHALGM VFGRKRPGSGPLMIGSIKPNIGHLEGAAGIAGLIKAVLMVERGSLLPSGGFTEPNPAIPFTELGLRVVDE LQEWPVVAGRPRRAGVSSFGFGGTNAHVIVEEAGSVGADTVSGRADVGGSGGGVVAWVISGKTASALAAQ AGRLGRYVRARPALDVVDVGYSLVSTRSVFDHRAVVVGQTRDELLAGLAGVVAGRPEAGVVCGVGKPAGK TAFVFAGQGSQWLGMGSELYAAYPVFAEALDAVVDELDRHLRYPLRDVIWGHDQDLLNTTEFAQPALFAV EVALYRLLMSWGVRPGLVLGHSVGELAAAHVAGALCLPDAAMLVAARGRLMQALPAGGAMFAVQAREDEV APMLGHDVSIAAVNGPASVVISGAHDAVSAIADRLRGQGRRVHRLAVSHAFHSALMEPMIAEFTAVAAEL SVGLPTIPVISNVTGQLVADDFASADYWARHIRAVVRFGDSVRSAHCAGASRFIEVGPGGGLTSLIEASL ADAQIVSVPTLRKDRPEPVSVMTAAAQGFVSGMGLDWASVFSGYRPKRVELPTYAFQHQKFWLAPAPSVS DPTAAGQIGASDGGAELLASSGFAARLAGRSADEQLAAAIEVVCEHAAAVLGRDGAAGLDAGQAFADSGF NSLSAVELRNRLTAVTAVTLPATAIFDHPTPTELAQYLITQIDGHGSSAAAAANPAERIDALTDLFLQAC DAGRDADGWKMVALASNTRERMSSPVRNNVSKNVALLADGISDVVVICIPTLTVLSDQREYRDIANAMTG RHSVYSLTLPGFDSSDALPQNADMIVETVSNAIIDVVGGSCRFVLSGYSSGGVLAYALCSHLSVKHQRNP LGVALIDTYLPSQIANPSMNEGFSPNDTGKGLSREVIRVARMLNRLTATRLTAAATYAAIFQAWEPGRSM APVLNIVAKDRIATVENLREERINRWRTAAAEAAYSVAEVPGDHFGMMSTSSEAIATEIHDWISGLVRGP HR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0405 | pks6 | - | 100% (1402) | PROBABLE MEMBRANE BOUND POLYKETIDE SYNTHASE PKS6 |
| M. tuberculosis H37Rv | Rv2048c | pks12 | 0.0 | 51.64% (974) | polyketide synthase pks12 |
| M. tuberculosis H37Rv | Rv1662 | pks8 | 0.0 | 48.63% (985) | polyketide synthase pks8 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0413 | pks6b | 0.0 | 99.89% (945) | polyketide synthase |
| M. gilvum PYR-GCK | Mflv_3393 | - | 0.0 | 40.00% (1135) | beta-ketoacyl synthase |
| M. leprae Br4923 | MLBr_00135 | - | 0.0 | 52.86% (891) | putative polyketide synthase |
| M. abscessus ATCC 19977 | MAB_0939 | - | 0.0 | 39.94% (1029) | polyketide synthase |
| M. marinum M | MMAR_0707 | pks6 | 0.0 | 56.64% (1379) | polyketide synthase Pks6 |
| M. avium 104 | MAV_2450 | - | 0.0 | 47.78% (1105) | erythronolide synthase, modules 3 and 4 |
| M. smegmatis MC2 155 | MSMEG_0408 | - | 0.0 | 41.16% (1013) | type I modular polyketide synthase |
| M. thermoresistible (build 8) | TH_4458 | - | 1e-157 | 41.82% (825) | PUTATIVE putative Fatty acyl-AMP ligase FadD28_1 and polyketide |
| M. ulcerans Agy99 | MUL_2266 | pks12 | 0.0 | 47.20% (1123) | polyketide synthase, Pks12 |
| M. vanbaalenii PYR-1 | Mvan_3128 | - | 0.0 | 40.72% (1002) | beta-ketoacyl synthase |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 MMVDQLQHATEALRKALVQVERLKRTNRALLERSSEPIAIVGMSCRFPGG
MUL_2266|M.ulcerans_Agy99 -MVDQLQHATEALRKALVQVERLKRTKRALLERSSEPIAIVGMSCRFPGG
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 ------------------------MDSAENPIESTPRFAIIGYAARFPG-
MSMEG_0408|M.smegmatis_MC2_155 ------------------------MVSAEHPIEPTPSFAIIGYAARFPG-
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 VDSPEALWQMVAEGRDVISEFPTDRGWDLAALYDPDPDARHKCYVNTGGF
MUL_2266|M.ulcerans_Agy99 VDSPEGLWQMVAEGRDVMSDFPTDRGWDLADLFDPDPDTPHKSYASTGGF
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 AADAEEFWDVLREGRDAISEVPADR-WDAEEFFDPEPGAPGKVVTRRAGF
MSMEG_0408|M.smegmatis_MC2_155 AASAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRAGF
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 VDNVADFDPAFFGIAPSEALAMDPQHRMLLELSWEALERAGIDPSGLRGS
MUL_2266|M.ulcerans_Agy99 VDGVADFDPGFFGIAPSEALAMDPQHRMLLELSWEALERSGIDPTGLRGS
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 VEDVTGFDAPFFGMSTREVRLMDPQHRLLLETAWRAVEHSGIAPTDLAET
MSMEG_0408|M.smegmatis_MC2_155 VDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANS
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 ATGVFAGLIVQGYG------MLAEEIEGYRLTGMTSSVASGRVSYVLGLE
MUL_2266|M.ulcerans_Agy99 ATGVFAGLIVQGYG------MFAEEIEGYRLTGMTSSVASGRVAYVLGLE
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 NSGVFVGLATHDYLGMASDELTFPEIEAYMAIGTSNAAAAGRISYRLGLQ
MSMEG_0408|M.smegmatis_MC2_155 NTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQ
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 GPAVSVDTACSSSLVALHMAVQSLRSGECDLALAGGATVNATPTVFVEFS
MUL_2266|M.ulcerans_Agy99 GPAVSVDTACSSSLVALHMAVQSLRSGECDLALAGGATVNATPTVFVEFS
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 GPSVAVDTACSSSLVAIHQACQALQLGECDLALAGGANVLLTPATMITFS
MSMEG_0408|M.smegmatis_MC2_155 GPAVAVDTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFS
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 RHRGLAPDGRCKAYAGAADGVGWSEGGAMLVVERLSDARRLGHPVLAVVR
MUL_2266|M.ulcerans_Agy99 RHRGLAPDGRSKAYAGAADGVGWSEGGAMLVVERLSDAQRLGHPVLALVR
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 HAHMLAPDGKCKTFDAAADGYVRGEGSGVIVIKRLEDAIRDGDRIRAVIR
MSMEG_0408|M.smegmatis_MC2_155 NAHMLAPDGRCKTFDAAADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIR
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 GSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTT
MUL_2266|M.ulcerans_Agy99 GSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTT
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 GSAINQDGASGGLTVPNGVAQQRVIADALKRAGVAPSEVGYLEAHGTGTS
MSMEG_0408|M.smegmatis_MC2_155 GSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPADVGYLEAHGTGTS
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 LGDPIEAQALLATYGQDRG------QPLWLGSIKSNMGHTQAAAGVAGVI
MUL_2266|M.ulcerans_Agy99 LGDPIEAQALLATYGQDRGSAGAAGKALWLGSIKSNMGHTQAAAGVAGVI
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 LGDPIEAQAAG----AAYGIGRETNDPLLIGSAKTNIGHLEAAAGIAGVI
MSMEG_0408|M.smegmatis_MC2_155 LGDPIEAQAAG----EVLGAGRAPEEPLLIGSAKTNIGHLEAAAGIAGVI
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 KMVLAMRHELLPATLHVDEPSPHVDWSAGAVSLLTEAQPWPGE----RPR
MUL_2266|M.ulcerans_Agy99 KMVQAMRHEVLPATLHVDVPSPHVDWSAGAVELLTEAQPWPAESAGDRVR
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 KVILSLENELLPQHRNFQNPSPHIPWDRLPVEVVREARP---WGRNGRPR
MSMEG_0408|M.smegmatis_MC2_155 KVVMALENETLPKHLNFETPSPHIPWERLPIEVVRETVP---WQRNGKPR
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 RAGVSSFGISGTNAHVIIEAVPAVEPAHADAPALPV----LPWVVSAKSA
MUL_2266|M.ulcerans_Agy99 RAGVSSFGISGTNAHVIVEAAPRVEVGGSSGGAVPV----VPWVVSAKSG
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 IAGVSSFGFAGTNAHVILEEAPVVSRDAVEPPAPAGGRKFSILPLSARTP
MSMEG_0408|M.smegmatis_MC2_155 IAGVSSFGFAGTNAHVILEEAPAVGTPATTEPVEDP-RRYSVLPLSARTP
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 AALRAQAARLAEYVRAQGELDIADVGWTLAGRATFEHRAVVVGGDRDRLL
MUL_2266|M.ulcerans_Agy99 SALGAQAARLAAHVRSHDELDVADVGWSLAGRSTFEHRAVVLGADRDGLL
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 AALAQLADKYRAWLNAHPEAALADLCFTAGVGRAHLEHRAALVVNTREAA
MSMEG_0408|M.smegmatis_MC2_155 EALVRLAGEYRDWLRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESA
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 AGLDELAADDP-AASIIRGVATPAGKTVFVFPGQGSQWLGMATELLDTAP
MUL_2266|M.ulcerans_Agy99 AGLDELAGDEFGGASVIRGVAGAAGKTVFVFPGQGSQWIGMGIELLDTAP
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 VELLSAVADDRPAPGLGRGESHDTPKTAWLFTGQGSQYPGMARELFETEP
MSMEG_0408|M.smegmatis_MC2_155 IELLGALADDRPAPGLVRGESHEAPKTAWLFTGQGSQYPGMARELFDTEP
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 VFAQHIQACEEAFAEFVDWSLIDALRGAPGAAG-----MDRVDVVQPALF
MUL_2266|M.ulcerans_Agy99 VFARHIESCGQAFAEFVDWSLLDVLRGAAGAPG-----LDRIDVVQPVLF
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 VFADTLNRCAAAVADVLEKPLLDVIFDVDGPE--AEETLRQTSYAQPALF
MSMEG_0408|M.smegmatis_MC2_155 VFAETVRKCAEAVADILEKPLLDVIFDADELDGDTESPLRHTTYAQPALF
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu ----------------------------------------------LLSL
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 AVMVSLAELWKSVGVSPDAVIGHSQGEIAAAYVAGALSLRDAARVVTLRS
MUL_2266|M.ulcerans_Agy99 AVMVSLAELWKSVGVRPDAVIGHSQGEIAAAYVAGALSLRDAAKVVTLRS
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 AVEMGLARLWQSWGFEPDVVLGHSVGQYSAACVAEVFSLEDGARLIAERG
MSMEG_0408|M.smegmatis_MC2_155 AVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERG
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu LRQRSERYGDKIAFDYCTGEQEHSRLTYQELDIRARAIAAHLQDQGVAGE
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 KLLRSLAGPGGMLSIACSTERARELLAPYGNRVSIAAVNGRSAVVVSGEG
MUL_2266|M.ulcerans_Agy99 KLLVGLAGPGGMVSVACGEQQARELLEPFGDRVSIAAINGPSAVVVSGEV
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 RLFSSLPAGGRMAAVFTDAERAERLTDEFPSLS--VAAYNGANTVLSGPA
MSMEG_0408|M.smegmatis_MC2_155 RLFGSLPAGGRMAAVFTAPERAERLTDEYPSLS--VAAYNGANTVLSGPA
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu RVLVLCPSGLDFITAMFGCFYVGAVAVPVHPPVHNRLLSRVASIVADVRA
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 AALDELAAFCADLALRTRRIDVDYASHSVEVEAIREDLAQALTGIEPRSS
MUL_2266|M.ulcerans_Agy99 AALEELIAQCADRELRTRRIDVDYASHSVEVEAIEGQLTEVLAGIEPLSS
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 QDLEKAIAALVADGVRCDFLETSHAFHSALLDPILDEFEAYANQFNYKTP
MSMEG_0408|M.smegmatis_MC2_155 KDLESAVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREP
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu TSVLTTAATRADLKEILDGLHDGDPLRWLAVDTIEADDETSWTPTTVDTD
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 RIAFFSTVTGNRL-DTAGLDADYWYRNIRQTVQFDQTVRSAAEHGYRTFI
MUL_2266|M.ulcerans_Agy99 RTAFFSSVTGSRL-DTAELDAEYWYRNIRQTVQFDQAVRSACGHGYRTFI
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 QRILIDNRTGTALGRSVKLDGAYWRRHARQPVEFAKSVRTLADMNCKVLL
MSMEG_0408|M.smegmatis_MC2_155 QRILIDNRTGSALGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLL
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu SVAFVQYTSGSTSTPKGVVLTHHNLLANLESISRDAGQGDEARVVSWLPL
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 ESSPHPALVAGIEDTVNDSLPG-DTEAIVIPTLGRDDGGLERFLTSAATA
MUL_2266|M.ulcerans_Agy99 ESSPHPALIAGIEDTYRNCAADSGADPIVVPTLGREDGGLQRFLASAAAA
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 EIGPQPVLTAAALRAWPDPATAPRAIASLRRNTADHRQITEAAADAYVLG
MSMEG_0408|M.smegmatis_MC2_155 EIGPRPVLTATALAAWPDPATTPQVLASLRPTTADHRQITEAVAAAYAAG
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu HHDMGLIGGIFGVVHFGGTAYLMPPSSFIQRPMSWLEAISWHGANISVGP
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 FVAGVNVAWRGVLDGAGFVELPTYAFDRRRFWLSGEGAAADASGLGLGTS
MUL_2266|M.ulcerans_Agy99 FVAGVNVDWRGPLDGAGLVELPTYAFEKRRFWLSGEGVSVDASGLGLSAG
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 HLPDFGAFQH---APARKLDLPTYPFERRQYWFSDKRDGDNRDAGNRQQN
MSMEG_0408|M.smegmatis_MC2_155 HLPDFRAFRQ---PDARKLDLPTYPFEHRQFWFSDNRAIDRDTQTASAGS
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu NFGYQLCVERSTPEERATLDLSTWVRAYCGAEPVRAATMRRFTEAFAPAG
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 EHPLLSAVVELPASGGVVLTGRLSPSLQGWLTDHAVSGTVVFPGAGFVEL
MUL_2266|M.ulcerans_Agy99 GHALLGAVVELPESGGVVLTGRLALGAHGWLADHAVSGVVVFPGTGFVEL
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 NGGPRTEAVRLLEDGKIEELANLLGGVD----------------------
MSMEG_0408|M.smegmatis_MC2_155 VTPHRTQAVRLLEDGQIEELAALIDGET----------------------
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu FRADAFHPVYGLAEATLFVSGRPE--------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 AIRAGDEVGCSTVEELTLQAPLMLPAKDSGIGSVAVQVLVGEADESGRRD
MUL_2266|M.ulcerans_Agy99 AIRAVDEVGCSVVNELTLRTPLVLPAS----GSVAVQVVVGAAADSAERS
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 ---------------------------------------GDQQTLNVLTK
MSMEG_0408|M.smegmatis_MC2_155 ---------------------------------------VDEQTLRVLNK
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 VSIFSRPDSD------SPWVCHAQGTLSTGSIEPGADLAAWPPAGATKVD
MUL_2266|M.ulcerans_Agy99 VSIYSRTDTDTDTDAGSVWVCHAEGTLGADSAQPAADLSAWPPAGAIAVD
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 LAAQHNLQRTTQTIADDRYQFRWEKSPTPLSGSQAAGGVTWLLVADAAGA
MSMEG_0408|M.smegmatis_MC2_155 LAARHNQQRSTHVDPDARYEIRWDAIASAAASTGAA--ADWILVGDDTAA
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 IADGYQRLAARGYGYGPAFQGLTAAWVRGDEVFAEVRLPDAAGGVTGFGV
MUL_2266|M.ulcerans_Agy99 VADGYERLDARGYGYGPAFRGLTAMWARGEELFAEARLPEAAGSTSGFGV
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 AQPLLDVLTARGQ-------------------------------------
MSMEG_0408|M.smegmatis_MC2_155 VLEFADALTAGGH-------------------------------------
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 HPALLDAAMHALIVGHQIAGDTDEVALPFAWQGVSLHAAGASAVRARLAP
MUL_2266|M.ulcerans_Agy99 HPALLDAALHTAVIANPDA----DLVLPFSWQGVSLHAAGAASVRVRIAP
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 AQAPGTAASRAVSLELADGLGLPVLSVRAMVARSVSERQLRAAVSAAGPD
MUL_2266|M.ulcerans_Agy99 VGPS------SVSVELADDLGLPVLSVKAMVARPVSEQQMRAVVSASGPD
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 --------------------------QHRVLALPVSDADEAELVEALRSA
MSMEG_0408|M.smegmatis_MC2_155 --------------------------RHQIVALPGSDADEAQLVDTLRAA
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 RLFEVAWAPVTVPAAHGEPPVHQVFESLAAEGDPVGESYRRTHEALAAVQ
MUL_2266|M.ulcerans_Agy99 RLFEVVWTPMTVAATDAAP-AYELFESIAADGDPLSGTYQRTHQALAAVQ
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 ADEDSALRIVHVAALAGQ--------------------------------
MSMEG_0408|M.smegmatis_MC2_155 SAG--ELYVVHIAAGDG---------------------------------
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 SWLTEHDSGVLVVVTRGAMALAGEDVTDLSGAAVWGLVRSAQTEHPGRIV
MUL_2266|M.ulcerans_Agy99 SWLTEHDSGVLVVATRGAMALAGEDVTDLAGAAVWGLVRSAQTENPGRLV
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 -----------------------------GSSSAQSLLRIQHQVLGGTRR
MSMEG_0408|M.smegmatis_MC2_155 -----------------------------AAAPMRDLLRVQHRTLGGLRR
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu -----------------------------------NVLPTVRSLDNAALR
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 LIDSDAALDDSALTAALATGEPQVLLRDGTVYTARVHGSRAVDGIMTPPE
MUL_2266|M.ulcerans_Agy99 LVDSDAAVDAAAVATALAVGEPQVVLRNGQPYTARVHASRAADGILVPPV
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 LFRAAAAAELRAPIWIVTRGAQHVIEGDTVAPEQSALWGFGRAAALELPQ
MSMEG_0408|M.smegmatis_MC2_155 LFRAANDAELRSPIWLVTRDGQRVTDTDTVVPEQSCLWGFGRAAALELPH
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu EHRVVPAAADDANAAAVVGCGPAAYGEEIVIVDPATRREFPPDVVGEIWV
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 DRPWRLGISSAGTFENLQLEPVPNPDAALQPGQVRVALRAIATNFRDVMI
MUL_2266|M.ulcerans_Agy99 DGPWRLGLSSAGTFENLQLEPVPNAGAPLGPGQVRVAMRAIAANFRDIMI
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 VWGGLADLSDAGTDEWAQFIGRVSVSGEASTREDQLALRGQAVHVPRLVR
MSMEG_0408|M.smegmatis_MC2_155 IWGGLADLSGADT-EWPRLIARITSPRDG---EDQIALRGDAVYAPRLVR
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu AGENVAQG----------------------------YLGKPSESAETFAA
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 TLGMFTHDALLGGEGAGVVVEVGPGVTEFSVGDSVYGFFPDGSGTLVPGD
MUL_2266|M.ulcerans_Agy99 TLGMFTHDALIGGEGAGVVVEIGPEVTEFAVGDAVYGFFPDGSGTLVAGD
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 REELPSGKPLEVRSDATYLVTGGLGSIGLEIAG-----------------
MSMEG_0408|M.smegmatis_MC2_155 RTGEPSDTPLPVREDRTYLVTGGLGAIGLEVAG-----------------
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu HLADSGRGPFLRTGDYGFLLDG----------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 VRLLQHKPTHWSYPEAAGISAVFTTAYMAFIHLADVKPGQRVLVHAAAGG
MUL_2266|M.ulcerans_Agy99 VRLLLPKPADWSYAEAAAISAVFTTAYYAFVHLANVQPGQRVLVHAATGG
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 VGMAAVQLARHLGLEVFATASRGKWDTLRAMGFDDDHIGDSRTLEFEDKF
MUL_2266|M.ulcerans_Agy99 VGMAAVQLARHLGLEVYATASKGKWDILRAMGFDEDHISDSRSLEFEEKF
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 RSATGGAGMDVVLDSLAGEFVDASLRLVAPGGVFLEMGKTDIRDPGVVAR
MUL_2266|M.ulcerans_Agy99 REVTGGRSVDVVLDSLAGEFVDASLRLLGPGGVFLEMGKTDIRDPGVIAQ
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 EYPGVRYRAFDLFEPGRPRMRQWMVELAGLFDAGVLNPLPVTTFDIRRGR
MUL_2266|M.ulcerans_Agy99 EYPGVRYRAFDLFEPGRPRMHQYMLDLAGLFDAGVLRPLPVTAFDVRRAP
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 AALRYLSQARHIGKVVMTVPG----ALSAGTVLITGGTGMAGSTLARHLV
MUL_2266|M.ulcerans_Agy99 AALRYLSQARHVGKVVMTMPADQGGALGGGTVLITGGTGMAGSALARHLV
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 ------------------------------------------------YL
MSMEG_0408|M.smegmatis_MC2_155 ------------------------------------------------YL
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 TGHGVRDLALLSRTGPDAPGAAEFVAELEAAGARVQVIACDAADRAALAG
MUL_2266|M.ulcerans_Agy99 AHHGVAHLVLISRRGPAAPGATELVAELSAAGAQVEVVACDAADRPALAK
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 AGRGAKHLVLTSRREPGEAARQRIDALAAQ-GCEVRAVTADVADGHDVAR
MSMEG_0408|M.smegmatis_MC2_155 ASHGAGHVVLTSRREPGDDARRRLDGLREQYACDVRVITADVADAHDVAR
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu -----------ELFVTGRLKDLIIIRGRNYHPNDIEATVQEVHPALMSGR
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 VIAGISAER-PLSGVIHAAGVLDDAMITSLTPERIDAVLRAKVDAAWNLH
MUL_2266|M.ulcerans_Agy99 VIAENPAQR-PLSAVVHAGGVLDDAVISSLTPERVDTVLRAKVDAAWNLH
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 LLAGIQAELPPLAGIVHAAGEIGTTPLSDLEDAEVDRVFAGKVWGAWHLS
MSMEG_0408|M.smegmatis_MC2_155 LMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLS
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu GAAFAVSPDPSGTEQLVIVQEVDRGRLGEVDTDELIAAIRTAVTSQHDIG
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 ELTRDMN--LSAFVMFSSMAGLVGSSGQGNYAAANSFLDALAAHRRAHGL
MUL_2266|M.ulcerans_Agy99 ELTRDLD--LSAFVMFSSMAGVVGSSGQANYAAANTFVDGLAAHRRAHGL
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 EAAAGLK--LDFFINTSSIAAVWGGYGQTAYSAANAFLDGLAWRLREQGI
MSMEG_0408|M.smegmatis_MC2_155 EALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRERGV
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu VHTVVLVDPLRIPTTSSGKIRRRTCRQRFLDGELDAFAEWRLATPRPAQP
Rv0405|M.tuberculosis_H37Rv ---------------MTDGSVTADKLQKWFREYLSTHIECHP--------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M ---------------MTDGLHSADALQEWFTHYIAARTGCDS--------
MAV_2450|M.avium_104 PAISLAWGLWDQASAMTGGLDAADLARLGRDGILALSSDEAMELFDTALI
MUL_2266|M.ulcerans_Agy99 PAISLGWGLWDQASDMTGGMDAADRARLGREGVLALSSDEAMELFDTALI
MLBr_00135|M.leprae_Br4923 ---------------MTASVEGADQK------------------------
MAB_0939|M.abscessus_ATCC_1997 AGTSVNFGPWSAGMADAESRARLEQRGIKTLSPTDALAGLADVVAASGSN
MSMEG_0408|M.smegmatis_MC2_155 TAVSVNFGPWAAGMADAESRARLEQRGVRTLSPAEALAGMADVVAG----
Mflv_3393|M.gilvum_PYR-GCK ----------------MTSASDEAAVRRWLIDYLVTNNGCSP--------
Mvan_3128|M.vanbaalenii_PYR-1 ----------------MTSAFDEDAIRNWLVDYLVTNIGCSP--------
TH_4458|M.thermoresistible__bu VPAADEQADEQAG-AGPGAGPGADEIRAWFVAQLAGELGLSP--------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 VDEPFLAPARIDLGALRAHAVAVPPMFADLVNAPTRRRVDDSLAAAKSKS
MUL_2266|M.ulcerans_Agy99 VNQAFLAPARIDLAALRAHAVAVPPMFSDLVSAPTRRQIDAALATAKSKS
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 AVQGVIARIDWARFLPLYQQAGKRGFLAELDREVPSHLAGVAG--AQSGS
MSMEG_0408|M.smegmatis_MC2_155 PVQGVVAKIDWSRFLPLYQQAGRRAFLSELESELPAAATGAAAPATVPGK
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv -----------------------------------NEVSLDVPIRDLGLK
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M -----------------------------------AEVNLDLPLRDLGLG
MAV_2450|M.avium_104 ALAHRLDGLPEAEQHAVLLELVRSHIATVLGSPTAEAIDPDKAFQELGFD
MUL_2266|M.ulcerans_Agy99 ALAHRLHGLPELEQHAVVLDLVRSHIATVLGTITPEAIDPDKAFQELGFD
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 TQLVERLANAPVQQRKKLLTDYLRDAVAEVTRVDVSEIREDAGFFDLGMD
MSMEG_0408|M.smegmatis_MC2_155 PPLVEQLTKAPVQQRKSLITNYLRNAVAEVTRVDADEIRDEAGFFDLGMD
Mflv_3393|M.gilvum_PYR-GCK -----------------------------------EHIERGASMHDLGVG
Mvan_3128|M.vanbaalenii_PYR-1 -----------------------------------DEINFDAPLNDLAVG
TH_4458|M.thermoresistible__bu -----------------------------------DDIDTGQPFAYYGLD
Rv0405|M.tuberculosis_H37Rv SIDVLAIPGDLGDRFGFCIPDLAVWDNPSANDLIDSLLNQRSADSLRESH
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M SIDVLAIPGELSDVLGICVPDLAVWDNPSAHDVIKSVLGGDGSQ--RSAD
MAV_2450|M.avium_104 SLTAVEMRNRLKTATGLALSPTLIFDYPTPNALAGYIR-----TELAGAP
MUL_2266|M.ulcerans_Agy99 SLTAVEMRNRIKTVTGLSLSPTLIFDYPTPNGLANYIR-----AELAGAP
MLBr_00135|M.leprae_Br4923 -----------------------------SEKLISYLK-----KVVVELD
MAB_0939|M.abscessus_ATCC_1997 SLMAVELRRRMEQGVGKEIPVTLVMDHPRISDVADYLLG-DVLGLAEQAK
MSMEG_0408|M.smegmatis_MC2_155 SLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLV-EVLGLGEQTN
Mflv_3393|M.gilvum_PYR-GCK SRDAVVLTGVLSEYLGRTVSPVDFWQYPTVDSLAKFLTG--GEVEP---I
Mvan_3128|M.vanbaalenii_PYR-1 SSDAVVLTGELSELLGRTVSPVEFWQYPTINALAKFLTG--GEVEPAIEA
TH_4458|M.thermoresistible__bu SVRAIQLMTALEAWSGIKVAPTLAYDHPTIDLAAEHLAGLTHTATSTAAD
Rv0405|M.tuberculosis_H37Rv GHADRNTQGR-------GSINEPVAVIGVGCRFPGD------IDGPERLW
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M SDTGCAVLGN-------GPTNEPIAVIGMACRFSGQ------VHGVGPLW
MAV_2450|M.avium_104 QETTHAPVVR-------ATDDDPIAIVGMSCRFPGG------VDSPEALW
MUL_2266|M.ulcerans_Agy99 QEVKHTPAVR-------VTGDDPIAIVGMSCRYPGG------IESPDDLW
MLBr_00135|M.leprae_Br4923 ETRARLREYE-------QRATEPVAVVGIGCRFPGG------VDSPDRLW
MAB_0939|M.abscessus_ATCC_1997 PAAQLASAVT-------GRTDEPIAIVAVSCRFPG-------APDPEAFW
MSMEG_0408|M.smegmatis_MC2_155 --VRQASTVT-------ARTDDPIAVVAVSCRFPG-------APDPESFW
Mflv_3393|M.gilvum_PYR-GCK EVGG-AARPA-------GMD-EPIAVIGLGLRLPGGDDLDGNIEGPDAYW
Mvan_3128|M.vanbaalenii_PYR-1 SVGGGVSRDY-------GADDEPIAVIGLGCRFPGGDGLDGNITGPDAYW
TH_4458|M.thermoresistible__bu AGVSTGAGRRPEHGPAPDRADEPIAIIGIGCRFPG-------ADGPAAYW
Rv0405|M.tuberculosis_H37Rv DFLTEKKCAITAYPDRGFTNAGT------------FAESGGFLKDVAGFD
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M DFLAEKKSAITEYPARRLGAAAADWLGD-----EQETIYGCFLEDVEGFD
MAV_2450|M.avium_104 QMVAEGRDVLSEFPTDRGWDLAGVYNPDPDVPGTCYTRTGGFVDNVADFD
MUL_2266|M.ulcerans_Agy99 DMLMARRDVLSDFPADRGWDLAGLFNPDPDVPGACYTRTGGFVDRVGDFE
MLBr_00135|M.leprae_Br4923 DVVSECRDVVSEFPTDRGWDVDGLFDPDPDAEGKTYTRWGAFLDDAAGFD
MAB_0939|M.abscessus_ATCC_1997 DVLSGGVDAIREVPEDR-FDIDEFYDPDPEVAGKTYTRFGGFLDGIDGFD
MSMEG_0408|M.smegmatis_MC2_155 ELLAGGVDAIREVPEDR-WDIDEFYDPDPDTPGKTYTRFGGFLDGIDGFD
Mflv_3393|M.gilvum_PYR-GCK DFLTEGRSSVREVPEDR-WSWFNDGTPEGAAALAATTRWGSYLRDLDAFD
Mvan_3128|M.vanbaalenii_PYR-1 RFLMEGRSAVRQVPEER-WESFQINTPEAAAALAGTTRWGAFLRDLDAFD
TH_4458|M.thermoresistible__bu RLLREGRDAITATPPER-WDTDSVGDG---------TRWGGFLERIDGFD
Rv0405|M.tuberculosis_H37Rv NRFFDIPPDEALRMDPQQRLLLEVSWEALEHAGIIPESLRLSRTGVFVGV
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M NKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKTLKLSHTGVFVGV
MAV_2450|M.avium_104 PAFFGIAPSEALAMDPQQRMFLELSWEALERAGIDPVKLRGSATGMFAGV
MUL_2266|M.ulcerans_Agy99 PAFFGVGPSEALAMDPQQRMFLELSWEALERAGIEPGGLRGSATGVFAGV
MLBr_00135|M.leprae_Br4923 AGFFGIAPSEVLAMDPQQRLMLEVSWEALEYAGIDPLSLRGSATGVFTGI
MAB_0939|M.abscessus_ATCC_1997 PEFFGISPREAVWIEPQQRLMLETVWEGLERAGYSPAALRGSRTGIFAGV
MSMEG_0408|M.smegmatis_MC2_155 PEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGV
Mflv_3393|M.gilvum_PYR-GCK AEFFEIMPREATRMDPQQRLLLEVTHEALENAGIAADALAETRTGVFAGA
Mvan_3128|M.vanbaalenii_PYR-1 AEFFEISPSEADKMDPQQRLLLEVTQEALEHAGIPTHTLRHSQTGVFAAA
TH_4458|M.thermoresistible__bu AGFFGISPREAVRIDPQQRLLLEVAWEALEDAGLVPDRLAGSRTGVFTGV
Rv0405|M.tuberculosis_H37Rv SSTDYVRLVSASAQQKSTIWDNTGGSSSIIANRISYFLDIQGPSIVIDTA
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M SSTDYVRLLFP-GGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTA
MAV_2450|M.avium_104 YTQGYG----MGAAPIAEGFRLTGQSSSVASGRVSYVLGLEGPAVSVDTA
MUL_2266|M.ulcerans_Agy99 MTQGYG----MFAAEPVEGFRLTGQLSSVASGRVAYVLGLEGPAVSVDTA
MLBr_00135|M.leprae_Br4923 FAPSYG----SRDTGGLQGYGLTGTAVSVASGRVSYVLGLEGPAVSVDTA
MAB_0939|M.abscessus_ATCC_1997 GANEYAHLLSSESIDKIEPYFITGNALNAISGRVAFALGFEGPAVAVDTA
MSMEG_0408|M.smegmatis_MC2_155 AANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTA
Mflv_3393|M.gilvum_PYR-GCK SAGDYAQMG-ATDLGGIDAWYGTGGSISIIANRVSYFFDLRGPSVTIDTA
Mvan_3128|M.vanbaalenii_PYR-1 CLGEYGYLS-TVDLGDVDSWSGTGGALSIIANRVSYYFDLRGPSVTIDTA
TH_4458|M.thermoresistible__bu STYDYLHLQ-LSHPELIDAYSGTGTASSIAANRLSYVFDFRGPSLTLDSA
Rv0405|M.tuberculosis_H37Rv CSSSLVAVHLACRSLSTWDCDIALVGGTNVLISPEPWGGFREAGILSQTG
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M CSSSLVAAHLARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTG
MAV_2450|M.avium_104 CSSSLVALHMAVQSLRSGECDLALAGGVTVNATPDIFVEFSRMRGLSVDG
MUL_2266|M.ulcerans_Agy99 CSSSLVALHMAVQSLRSGECDLALAGGVTINATPDIFVEFSRWRGLSADG
MLBr_00135|M.leprae_Br4923 CSSSLVAIHWAMSSLRSGECDLALAGGVTVMGLPSIFVGFSRQRGLAADG
MAB_0939|M.abscessus_ATCC_1997 CSSALVAVHQAVQALHSGDCDLALAGGVNVLLSPVTVIAASRARMLSPVG
MSMEG_0408|M.smegmatis_MC2_155 CSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVG
Mflv_3393|M.gilvum_PYR-GCK CSSSLVAVHLAAQSLRTGDSDLALAAGVNLLLSPAGTRGLDQAEALSPTG
Mvan_3128|M.vanbaalenii_PYR-1 CSSSLVTIHLACQSLRSGDSNMALAAGVNLLLSPAVTRSFDQLEAMSRTG
TH_4458|M.thermoresistible__bu CSSSLVAVHQACRSLRDGECDLALAGGVNIMLSAGIGLNFTRAGVMATDG
Rv0405|M.tuberculosis_H37Rv CCHAFDKSADGMVRGEGCGVIVLQRLSDARLEGRRILAILTGSAVNQDGK
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M SCRAFDARADGMVRGEGCGVVVLERLSDARRAGRTVLAVLTGSAVNQDGR
MAV_2450|M.avium_104 RCKAYAGAADGTGFSEGGGMLVVERLSDARRLGHPVLAVVRGSAVNQDGA
MUL_2266|M.ulcerans_Agy99 RCKAFAGAADGTGFSEGGGMLVVERLSDAQRLGHPVLALVRGSAVNQDGA
MLBr_00135|M.leprae_Br4923 RCKAFARAADGTGWGEGAGVVVLERLSDAQRLGHTVLAVVRGSAVNQDGA
MAB_0939|M.abscessus_ATCC_1997 RCKTFDASADGYVRSEGCGILVLKRLSDAERDGDRVLAVIPGSAVNQDGA
MSMEG_0408|M.smegmatis_MC2_155 RCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGA
Mflv_3393|M.gilvum_PYR-GCK QCHAFDASADGFVRGEGCGVAVLKRLSDAQRDGDRVLAVIRGSAVNQDGR
Mvan_3128|M.vanbaalenii_PYR-1 QCHAFDAGADGFVRGEGCGVTVLKRLSDAQRDGDRILAVIRGSAVNQDGR
TH_4458|M.thermoresistible__bu RCKTFDARADGWVRGEGAGIVVLKPLREALADEDPIYAVIRGSAVNQDGR
Rv0405|M.tuberculosis_H37Rv SNGIMAPNPSAQIGVLENACKSARVDPLEIGYVEAHGTGTSLGDRIEAHA
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M SNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAHA
MAV_2450|M.avium_104 SNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQA
MUL_2266|M.ulcerans_Agy99 SNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQA
MLBr_00135|M.leprae_Br4923 SNGLTAPNGLAQQRVIQAALTNAGLSSADVDVVEAHGTATTLGDPIEAQA
MAB_0939|M.abscessus_ATCC_1997 SSGLTVPNGGAQQRLIGSVLARAGLVGGDVDYLEAHGTGTPLGDPIEVQA
MSMEG_0408|M.smegmatis_MC2_155 SSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQA
Mflv_3393|M.gilvum_PYR-GCK SNGLMAPNPSAQIAVLRAAYAAAGVNPREVDYVEAHGTGTLLGDPIEARA
Mvan_3128|M.vanbaalenii_PYR-1 SNGLMAPNPAAQMAVLRSAYSAAGVEPRDVDYVETHGTGTLLGDPIEARA
TH_4458|M.thermoresistible__bu TNGLMAPSRTAQEVVLTDAYRRAGVSPGVVQYVEAQGIGTPVGDAIEVGA
Rv0405|M.tuberculosis_H37Rv LGMVFGRKRP----GSGPLMIGSIKPNIGHLEGAAGIAGLIKAVLMVERG
Mb0413|M.bovis_AF2122/97 -------------------------------------------MLMVERG
MMAR_0707|M.marinum_M LGQVFGRGRQ----AAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRG
MAV_2450|M.avium_104 LLATYGQDRG------QPLWLGSIKSNMGHTQAAAGVAGVIKMVLAMRHE
MUL_2266|M.ulcerans_Agy99 LLATYGQDRGSAGAAGKALWLGSIKSNMGHTQAAAGVAGVIKMVQAMRHE
MLBr_00135|M.leprae_Br4923 LLATYGQGRP----ADQPLWVGSIKSNMGHTQAAAGVAGVIKMVQAMRHH
MAB_0939|M.abscessus_ATCC_1997 AAAAYGGSRD----ADRPLLMGSVKSNIGHTESASGAAGLIKVVLSLQNG
MSMEG_0408|M.smegmatis_MC2_155 AAAAYGAGRD----ADRPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHG
Mflv_3393|M.gilvum_PYR-GCK LGTVLGKGRP----ADAPLMIGAVKSNLGHLEAAAGIAGFAKAVLALQHN
Mvan_3128|M.vanbaalenii_PYR-1 LGTVLGRGRA----ADAPLLLGAVKSNLGHLEAAAGVAGFIKAVLALQHQ
TH_4458|M.thermoresistible__bu LGTVLAEDRP----PDSPCLIGSVKTNIGHLEAAAGIAGLIKVALALRHR
:..
Rv0405|M.tuberculosis_H37Rv SLLPSGGFTEPNPAIPFTELGLRVVDELQEWPVVAG--RPRRAGVSSFGF
Mb0413|M.bovis_AF2122/97 SLLPSGGFTEPNPAIPFTELGLRVVDELQEWPVVAG--RPRRAGVSSFGF
MMAR_0707|M.marinum_M QLLPSGAFEVPNPNIPFAELGLAVVEEFQEWPAVVG--RPRRAGVSSFGF
MAV_2450|M.avium_104 LLPATLHVDEPSPHVDWSAGAVSLLTEAQPWPGE----RPRRAGVSSFGI
MUL_2266|M.ulcerans_Agy99 VLPATLHVDVPSPHVDWSAGAVELLTEAQPWPAESAGDRVRRAGVSSFGI
MLBr_00135|M.leprae_Br4923 VMPATLHVDEPSPRVDWTTGAVSVLTEARDWSVEG---RPRRAGVSSFGI
MAB_0939|M.abscessus_ATCC_1997 VLPQSLHFDNPSPHIPWESLPVRVVDKAIPWQANGR---PRRAGVSSFGF
MSMEG_0408|M.smegmatis_MC2_155 VLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGR---VRRAGVSSFGF
Mflv_3393|M.gilvum_PYR-GCK RIPGNRGWQTPNPHIPFDKLRLRVIDEHTDW-APAGR--PRRAGISSFGF
Mvan_3128|M.vanbaalenii_PYR-1 QIPANLGYEKPNPHIPFDNLRLKVIAEHTEWPAPAGR--PRRAGVSSFGF
TH_4458|M.thermoresistible__bu MIPPTLNFTEPNPTIEFDKLPVRVAQTLTPWPDDSGR---AVAGVSAFGF
: . *.* : : : : * **:*:**:
Rv0405|M.tuberculosis_H37Rv GGTNAHVIVEEAGS--------VG--------------------------
Mb0413|M.bovis_AF2122/97 GGTNAHVIVEEAGS--------VG--------------------------
MMAR_0707|M.marinum_M GGTNAHVIVEQAVERVVERVVEVGPGVLAWVVSARTAAGVGAQAGRLLEF
MAV_2450|M.avium_104 SGTNAHVIIEAVPA------------------------------------
MUL_2266|M.ulcerans_Agy99 SGTNAHVIVEAAPR------------------------------------
MLBr_00135|M.leprae_Br4923 SGTNAHVILEEAPTP-----------------------------------
MAB_0939|M.abscessus_ATCC_1997 TGTNAHVLIEEAPQPQ----------------------------------
MSMEG_0408|M.smegmatis_MC2_155 TGTNAHVLVEEAPPQL----------------------------------
Mflv_3393|M.gilvum_PYR-GCK GGTNAHVVIEQAPVLP----------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 GGTNAHVVIEQAPPKA----------------------------------
TH_4458|M.thermoresistible__bu GGTNAHVVLAEAPQVR----------------------------------
******:: .
Rv0405|M.tuberculosis_H37Rv -----------------------------------------ADTVSGRAD
Mb0413|M.bovis_AF2122/97 -----------------------------------------ADTVSGRAD
MMAR_0707|M.marinum_M VRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPG
MAV_2450|M.avium_104 -------------------------------------------VEPAHAD
MUL_2266|M.ulcerans_Agy99 -------------------------------------------VEVGGSS
MLBr_00135|M.leprae_Br4923 -------------------------------------------VEASYST
MAB_0939|M.abscessus_ATCC_1997 ------------------------------------ATPDEDDASTPQSA
MSMEG_0408|M.smegmatis_MC2_155 ------------------------------------HTADAAPVEPAATA
Mflv_3393|M.gilvum_PYR-GCK -------------------------------------------PTPGEAP
Mvan_3128|M.vanbaalenii_PYR-1 -------------------------------------------PATNGQG
TH_4458|M.thermoresistible__bu -----------------------------------------AAATADDHA
Rv0405|M.tuberculosis_H37Rv VGGS----------------------------------------------
Mb0413|M.bovis_AF2122/97 VGGS----------------------------------------------
MMAR_0707|M.marinum_M VGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPVFAAAFDAVVAEL
MAV_2450|M.avium_104 AP------------------------------------------------
MUL_2266|M.ulcerans_Agy99 GG------------------------------------------------
MLBr_00135|M.leprae_Br4923 ADQQ----------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 PVS-----------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155 EAGT----------------------------------------------
Mflv_3393|M.gilvum_PYR-GCK EG------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 EP------------------------------------------------
TH_4458|M.thermoresistible__bu DG------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M DRHLARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGL
MAV_2450|M.avium_104 --------------------------------------------------
MUL_2266|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M VMGHSVGELSAAHVSGVLDLADAALLVVMRGRLMQALPGGGVMYAVQAGE
MAV_2450|M.avium_104 --------------------------------------------------
MUL_2266|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M QELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAV
MAV_2450|M.avium_104 --------------------------------------------------
MUL_2266|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M SHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADY
MAV_2450|M.avium_104 --------------------------------------------------
MUL_2266|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M WVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVA
MAV_2450|M.avium_104 --------------------------------------------------
MUL_2266|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M VPTLRKDRPEPFAVVGAVAQAFVRGAGVDWASVLAGCGGQRVGLPTYAFA
MAV_2450|M.avium_104 --------------------------------------------------
MUL_2266|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M HERFWLADRFGVGQQVCVGQVLADEAGPGAHEAAGAAVGQGFAARLQGLS
MAV_2450|M.avium_104 --------------------------------------------------
MUL_2266|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M DAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNR
MAV_2450|M.avium_104 --------------------------------------------------
MUL_2266|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M LKTLTGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRID
MAV_2450|M.avium_104 --------------------------------------------------
MUL_2266|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M EPIAIVGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDP
MAV_2450|M.avium_104 --------------------------------------------------
MUL_2266|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M DPDALGKTYTRHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWE
MAV_2450|M.avium_104 --------------------------------------------------
MUL_2266|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M ALEDAGIDPQALRGSSTGVFVGIYGDGYGLGTSQAQWYADTGHITSVASG
MAV_2450|M.avium_104 --------------------------------------------------
MUL_2266|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M RISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDLALAGGSTVLA
MAV_2450|M.avium_104 --------------------------------------------------
MUL_2266|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M TPSIFIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRA
MAV_2450|M.avium_104 --------------------------------------------------
MUL_2266|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M GQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDV
MAV_2450|M.avium_104 --------------------------------------------------
MUL_2266|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M VEAHGTGTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAG
MAV_2450|M.avium_104 --------------------------------------------------
MUL_2266|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M VAGVIKMVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVG
MAV_2450|M.avium_104 --------------------------------------------------
MUL_2266|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv -----------------------------------GGGVVAWVISGKTAS
Mb0413|M.bovis_AF2122/97 -----------------------------------GGGVVAWVISGKTAS
MMAR_0707|M.marinum_M RPRRAGVSSFGVSGTNAHVIVEQAVERVVERVVEVGPGVLAWVVSARTAA
MAV_2450|M.avium_104 -----------------------------------ALPVLPWVVSAKSAA
MUL_2266|M.ulcerans_Agy99 -----------------------------------AVPVVPWVVSAKSGS
MLBr_00135|M.leprae_Br4923 -----------------------------------RLSVVPWVVSGRSTA
MAB_0939|M.abscessus_ATCC_1997 ----------------------------------------VLPLSARSPE
MSMEG_0408|M.smegmatis_MC2_155 -----------------------------------DDSPQVLALSARSPE
Mflv_3393|M.gilvum_PYR-GCK -------------------------------------AVTTLVVSGKSAE
Mvan_3128|M.vanbaalenii_PYR-1 -------------------------------------AVTTLVVSGRTAE
TH_4458|M.thermoresistible__bu -------------------------------------FVEILPLSARSQA
:*.::
Rv0405|M.tuberculosis_H37Rv ALAAQAGRLGRYVRARP--ALDVVDVGYSLVSTRSVFDHRAVVVGQTRDE
Mb0413|M.bovis_AF2122/97 ALAAQAGRLGRYVRARP--ALDVVDVGYSLVSTRSVFDHRAVVVGQTRDE
MMAR_0707|M.marinum_M GVGAQAGRLLEFVRAGR--ELDAGDVGYSLVTTRSLFEHRAVVVGAGRDE
MAV_2450|M.avium_104 ALRAQAARLAEYVRAQG--ELDIADVGWTLAG-RATFEHRAVVVGGDRDR
MUL_2266|M.ulcerans_Agy99 ALGAQAARLAAHVRSHD--ELDVADVGWSLAG-RSTFEHRAVVLGADRDG
MLBr_00135|M.leprae_Br4923 ALMAQASRLAFYVQADP--EVDPVDVGCALAA-RSVFEHRAVVVGESREQ
MAB_0939|M.abscessus_ATCC_1997 ALAAVAQRYESWLAAHP--DVDLEDVCLTAGRGRSHFEHRAALVVDSIQT
MSMEG_0408|M.smegmatis_MC2_155 ALVELARRYDDWLSATP--GLDIADVCHTAGVGRSHFEYRAALVVDSVER
Mflv_3393|M.gilvum_PYR-GCK RIATHAAALAVWMDGTD---ASLTEVAHTLNHHRTQHPRFATVTARDKAQ
Mvan_3128|M.vanbaalenii_PYR-1 RIASEAGMLAEWMAGPEGSLASLPEVAHTLNHHRSHYNKFATVAARDRDQ
TH_4458|M.thermoresistible__bu ALDALAERYESALTGGVP----PADLCHTAGARRAHHDHRLAVVGASRAE
: * : . :: : *: . .:
Rv0405|M.tuberculosis_H37Rv LLAGLAGVVAGRP--EAGVVCGVGKPAGKTAFVFAGQGSQWLGMGSELYA
Mb0413|M.bovis_AF2122/97 LLAGLAGVVAGRP--EAGVVCGVGKPAGKTAFVFAGQGSQWLGMGSELYA
MMAR_0707|M.marinum_M LLAGLAEVVEGRP--GVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCA
MAV_2450|M.avium_104 LLAGLDELAADDP--AASIIRGVATPAGKTVFVFPGQGSQTLGMGRQLHA
MUL_2266|M.ulcerans_Agy99 LLAGLDELAGDEFG-GASVIRGVAGAAGKTVFVFPGQGSQLLGMGMGLHA
MLBr_00135|M.leprae_Br4923 LIAGLAGLAVGES--GAGVAIGQAAPLGKTVVVFPGQGAQRIGMGRELCS
MAB_0939|M.abscessus_ATCC_1997 AREGLLELAQNRL--RPGVVRGEHTNHPTTAWLFTGQGSQYPGMARELFD
MSMEG_0408|M.smegmatis_MC2_155 AREGLAALAEGRT--PAGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFD
Mflv_3393|M.gilvum_PYR-GCK AVAGLSALAAGQTV-PGVVAAATATPKPGTVFVYSGQGSQWPGMARRLLA
Mvan_3128|M.vanbaalenii_PYR-1 AIAGLRALAAGQTA-PGVVGAPTGARKRGTVFVYSGQGSQWPGMARQLLA
TH_4458|M.thermoresistible__bu LIGALAAYRRGEPHPGVFTGRSQSGHRSGVVFVFSDEGSQWRGMAQRLYA
.* . .. ::..:*:* **. *
Rv0405|M.tuberculosis_H37Rv AYPVFAEALDAVVDELDRHLRYPLRDVIWGH-------DQDLLNTTEFAQ
Mb0413|M.bovis_AF2122/97 AYPVFAEALDAVVDELDRHLRYPLRDVIWGH-------DQDLLNTTEFAQ
MMAR_0707|M.marinum_M GYPVFAAAFDAVVAELDRHLARPLREVVWGA-------DAELLNTTEFAQ
MAV_2450|M.avium_104 GYPVFAEAFDAVVAELDRHLLRPLRDVIWGD-------DENVLNSTEFAQ
MUL_2266|M.ulcerans_Agy99 GYPVFAEAFNTVVGELDRHLLRPLREVIWGH-------DENLLNTTEFAQ
MLBr_00135|M.leprae_Br4923 QLPVFAEEFDAVTGELDRHMRLPLRDVVWGA-------DAGLLDSTEFAQ
MAB_0939|M.abscessus_ATCC_1997 AEPVFAETVTRCAEAVKDIVTRPLLEVMFATDRETGGKAGEALRHTSFAQ
MSMEG_0408|M.smegmatis_MC2_155 TQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRET----ADLLQHTSFAQ
Mflv_3393|M.gilvum_PYR-GCK DEPVFAEALDEIEPLFAEHVGFSLRDVIAGG---------REVSGDAEVQ
Mvan_3128|M.vanbaalenii_PYR-1 DEPAFANALAEIEPVFVEQVGFSLRDVIAGG---------ETVSGDAQVQ
TH_4458|M.thermoresistible__bu EDQVFRTALAECDRALRRHMEISPLSELLADP------SHSRMDEVTIAS
.* . . : . . : . : ..
Rv0405|M.tuberculosis_H37Rv PALFAVEVALYRLLMSWGVRPGLVLGHSVGELAAAHVAGALCLPDAAMLV
Mb0413|M.bovis_AF2122/97 PALFAVEVALYRLLMSWGVRPGLVLGHSVGELAAAHVAGALCLPDAAMLV
MMAR_0707|M.marinum_M PALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGVLDLADAALLV
MAV_2450|M.avium_104 PALFAVEVALFRLLESWGVRPDFVMGHSIGELSAAHVAGVLSLQNAAVLV
MUL_2266|M.ulcerans_Agy99 PALFAVEVALYRLLESWGVRPDFVMGHSVGELSAAHVAGVLSLENAAVLV
MLBr_00135|M.leprae_Br4923 PALFAVEVALFAVLQHWGLQPDFVMGHSIGELAAAYVAGVLAPADAAMLV
MAB_0939|M.abscessus_ATCC_1997 PALFAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVAGVFSIEDGARLI
MSMEG_0408|M.smegmatis_MC2_155 PALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLM
Mflv_3393|M.gilvum_PYR-GCK PVLMGVQLALTQLWRSYGVHPDAVIGHSMGEVTAAVVAGALDVADGLKVI
Mvan_3128|M.vanbaalenii_PYR-1 PVLMGLQLALTELWRSYDVHPDAVIGHSMGEVTAAVVAGALSLADGLKVI
TH_4458|M.thermoresistible__bu PALFAVQVALAALWQSWGVEPAAVIGHRMGEVAAAHVAGVLGLDDAAALL
*.*:.:::.* : : :.* *:** :*: :** *:*.: :. ::
Rv0405|M.tuberculosis_H37Rv AARGRLMQALPAGGAMFAVQAREDEVAPMLGHD--VSIAAVNGPASVVIS
Mb0413|M.bovis_AF2122/97 AARGRLMQALPAGGAMFAVQAREDEVAPMLGHD--VSIAAVNGPASVVIS
MMAR_0707|M.marinum_M VMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQ--VSVAAVNGPGSVVLS
MAV_2450|M.avium_104 AARGRFMQALPEGGAMIAVQATEAQVRPLLGPD--VGIAAVNGPAAVVIS
MUL_2266|M.ulcerans_Agy99 AARGRLMQALPDGGAMIAVQATEQEVLPLLGAQ--VSIATINGPASVVIS
MLBr_00135|M.leprae_Br4923 VARGRLMQSMPAGGTMWAVAASEDEVVSLLGEG--VGIAAINAPESVVIS
MAB_0939|M.abscessus_ATCC_1997 AERGRLFGGLPAGGRMVAVFSDAKHVEQIAGEFPRVSVGAYNGP-NTVLS
MSMEG_0408|M.smegmatis_MC2_155 AERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNGP-NTVLS
Mflv_3393|M.gilvum_PYR-GCK AARSTIMSRLAGQGAVALLNVDADECAALIGGHPSVEIAGYLSPHQTVVA
Mvan_3128|M.vanbaalenii_PYR-1 AARSSIMSRLAGQGAVALVELDPEAAAAFIADYPSVEVAGFVSPRQTVVA
TH_4458|M.thermoresistible__bu CGRTRLSRLASTG-------------------------------------
* : .
Rv0405|M.tuberculosis_H37Rv GAHDAVSAIADRLRGQGRRVHRLAVSHAFHSALMEPMIAEFTAVAAELSV
Mb0413|M.bovis_AF2122/97 GAHDAVSAIADRLRGQGRRVHRLAVSHAFHSALMEPMIAEFTAVAAELSV
MMAR_0707|M.marinum_M GAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYA
MAV_2450|M.avium_104 GDHDAAVAIAERLRAEGHRVHRLSVSHAFHSPLMEPMIDEFGTVAAGLAI
MUL_2266|M.ulcerans_Agy99 GAQDAVSAVAEQLRADGRRVHRLAVSHAFHSPLMDPMIDEFATVAGELTV
MLBr_00135|M.leprae_Br4923 GPQAAVSAIADKFAAQGRRVHQLAVSHAFHSPLMEPMLEEFVRVAAQVEV
MAB_0939|M.abscessus_ATCC_1997 GPGEDLEQAVARFQEEGIRCTWLETSHAFHSELLDPILDEFESYAAQVQF
MSMEG_0408|M.smegmatis_MC2_155 GPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDEFEAYAAQFQF
Mflv_3393|M.gilvum_PYR-GCK GLPEEVDAVIATVTSLNTFARRVNMVVASHTALMDPVLDDIRSALSDVDP
Mvan_3128|M.vanbaalenii_PYR-1 GLPEQVDAVIAAVTAQEKFARRVNMEVASHTALMDPVLPDLREALAGVTP
TH_4458|M.thermoresistible__bu -----------------------------------AVREGLDGLLANLRP
.: : .
Rv0405|M.tuberculosis_H37Rv GLPTIPVISNVTG-QLVADDFASADYWARHIRAVVRFGDSVRSAHCAGAS
Mb0413|M.bovis_AF2122/97 GLPTIPVISNVTG-QLVADDFASADYWARHIRAVVRFGDSVRSAHCAGAS
MMAR_0707|M.marinum_M GRPAIPVISNVTG-QLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGAT
MAV_2450|M.avium_104 DKPVIPIISNLTG-QPAADDFGSPEYWKCHVRDAVRFADSVRFAQSAGAT
MUL_2266|M.ulcerans_Agy99 NAPTIGIISNLTG-QLAGEDFGSAAYWKRHVRDAVRFADSIRFAQSAGAA
MLBr_00135|M.leprae_Br4923 RKPQIGLVSNVTG-ELAGPDFGSPQYWGEHVSRAVRFVDSARHLQTLGAT
MAB_0939|M.abscessus_ATCC_1997 AAPTLPLVCNRTGAVLTAQTPIDGQYWRRHSRQPVQFAESVRTVAALGCS
MSMEG_0408|M.smegmatis_MC2_155 AAPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCS
Mflv_3393|M.gilvum_PYR-GCK NIPSLPFLSTVTD--PGVTPEFDADYWVSNVRQPVRFSQAVSAAATEYG-
Mvan_3128|M.vanbaalenii_PYR-1 RTPNIPFLSTVTE--PDGEPALDADYWVANVRQPVKFSQAVTAAAQEIG-
TH_4458|M.thermoresistible__bu DDPRIPLYSTVTGDAVTGRGFG-AAHWMENLHSPVRFSAAVRRLLGRGHD
* : . .. * :* : *:* :
Rv0405|M.tuberculosis_H37Rv RFIEVGPGGGLTSLIEASLADA----QIVSVPTLRKDRPEPVSVMTAAAQ
Mb0413|M.bovis_AF2122/97 RFIEVGPGGGLTSLIEASLADA----QIVSVPTLRKDRPEPVSVMTAAAQ
MMAR_0707|M.marinum_M RFVEVGPAGGLTSLIEESLAQV----SVVAVPTLRKDRPEPFAVVGAVAQ
MAV_2450|M.avium_104 RFLEVGPSSGLTAAIEETLADA----PVVTVSALRKDRPEPVALVNAVAQ
MUL_2266|M.ulcerans_Agy99 RFLEVGPSIGLTASIEEVLSDAAVTNPVATASALRKDRPEPVSLVSALAG
MLBr_00135|M.leprae_Br4923 HFIESGPSSGLMGAIEQSLAPA----EAVVVSMMGKDRPELASVLGAAGQ
MAB_0939|M.abscessus_ATCC_1997 VLMEIGPQPVLTGAAVQVWPEH--LAPPRAIVSLRKGVEDRRQIADALAS
MSMEG_0408|M.smegmatis_MC2_155 VLMEIGPQPVLTGAAVQVWPEH--MAAPRAVASLRKGVADRRQIADALAS
Mflv_3393|M.gilvum_PYR-GCK TFVEISPHPTLGQSIRDTLGDG---ADHLVVGTLARDADDTVAFHASVNA
Mvan_3128|M.vanbaalenii_PYR-1 TFIEVSANPILTYAINDTLSS----ASHVSLGTLARDADDTLTFHTALNA
TH_4458|M.thermoresistible__bu AFLEISAHPMLLSAVQEDAADLG--RSCTTLVSMRRGECGRDVLMTSLAA
::* .. * : :. . :
Rv0405|M.tuberculosis_H37Rv GFVSGMGLDWASVFSGYRPKRVELPTYAFQHQKFWLA-----------PA
Mb0413|M.bovis_AF2122/97 GFVSGMGLDWASVFSGYRPKRVELPTYAFQHQKFWLA-----------PA
MMAR_0707|M.marinum_M AFVRGAGVDWASVLAGCGGQRVGLPTYAFAHERFWLA-----------DR
MAV_2450|M.avium_104 GWVCGMDVDWRGALG--TGHLVDLPTYAFDRRRFWLS-GDGAASDAAGLG
MUL_2266|M.ulcerans_Agy99 VFVAGTAVDWRAVVG--QSHFVELPTYAFERRRFWLS-GDAVPADAAGLG
MLBr_00135|M.leprae_Br4923 LFATGMPVEWPAVFAGSSRRRVTLPTYAFQRRRFWETPGTDGTASVSGLG
MAB_0939|M.abscessus_ATCC_1997 AYVSGHRPNFAALQR-HPRRTVELPTYPFQRRRFWPK------SSGTAIE
MSMEG_0408|M.smegmatis_MC2_155 AYVGGHRPDFAAVHR-QPRRPVELPTYPFQRRRFWPK------ASSIAVD
Mflv_3393|M.gilvum_PYR-GCK THTS-----RPPHTPHGPEPHLVLPATPWHHTRHW-IDVRP----ARRSG
Mvan_3128|M.vanbaalenii_PYR-1 TFTG-----HPPVTPHHGEPHIQLPTTPWHHTHHWAIRKHT----ASGAT
TH_4458|M.thermoresistible__bu LYASGHAVDWARVHP-HGSHCTAAPTYPWQRQRFWLD-------------
. *: .: : :.*
Rv0405|M.tuberculosis_H37Rv PSVSDPTAAGQIG--ASDGG------AELLASSGFAARLAG---------
Mb0413|M.bovis_AF2122/97 PSVSDPTAAGQIG--ASDGG------AELLASSGFAARLAG---------
MMAR_0707|M.marinum_M FGVGQQVCVGQVL--ADEAGPGAHEAAGAAVGQGFAARLQG---------
MAV_2450|M.avium_104 LAAGDHALLGAVVELPASGGVLLTGRLSPASQGWLADHAVGGVVLFPGAG
MUL_2266|M.ulcerans_Agy99 LQAGEHALLGAVVELPASGGVVLTGRLSLAAQGWLADHAVGGVVIFPGAG
MLBr_00135|M.leprae_Br4923 LGSTEHALLGAVVERPDSGGVVLTGRLSLANQPWLADHVIGGVVLFPGAG
MAB_0939|M.abscessus_ATCC_1997 GGGGLPSGILGRGEDLASGDSVYISRLSVRSQPWLSDHVIYGTVVVPG--
MSMEG_0408|M.smegmatis_MC2_155 GG-TAASGILGSGKDLASGDTIYTSRLSVKSQPWLADHVIYGTVVVPG--
Mflv_3393|M.gilvum_PYR-GCK GVRAGAVP------AGSPVPPEWFCELTWPAKPLAAHHDPE---------
Mvan_3128|M.vanbaalenii_PYR-1 APRPGTVLGSHTAVAGTQPGHLWQARLAPQAKPYPQPHKFAGVEIVPLSV
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv ------RSADEQLAAAIEVVCEHAAAVLGRDGAAGLDAGQAFADSG----
Mb0413|M.bovis_AF2122/97 ------RSADEQLAAAIEVVCEHAAAVLGRDGAAGLDAGQAFADSG----
MMAR_0707|M.marinum_M ------LSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAG----
MAV_2450|M.avium_104 FVELAIRAGDEVGCGIIDELNLAAPLVLPAGGSVAIQVVVDGPDDSGARA
MUL_2266|M.ulcerans_Agy99 FVELAIRAGDEVGCRVVDELTLAAPLVLPSGGSVAVQVVVGSPDDSGARA
MLBr_00135|M.leprae_Br4923 FVELVIRAGDEVGCAGVEELVLAAPLVLHPGSGVQVQVVVAAADESSRRA
MAB_0939|M.abscessus_ATCC_1997 ATYAAMALAAVGTPARAKDVFFYEPIILPEKSSREVQLTLHPLEDGSGSK
MSMEG_0408|M.smegmatis_MC2_155 ATYAAMALAAVGTPARLKDVFFYEPIILPEKASREVQLTLHPADGGSVLS
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 LLQTLSLAAAESGARAVADVRFDFPITVDAPRVVQVVSDGETITVSSSTA
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 VSVFSRAD-----------AGAGWLLHAEGVLRAGSAQPATDLSAWPPVG
MUL_2266|M.ulcerans_Agy99 VSVYSRGD-----------AGSDWVLHAEGSLGSGSPEPATDLSTWPPVG
MLBr_00135|M.leprae_Br4923 VSVYSRGDQ----------SHGGWLLNAEGLLEVDAAEATVDLSLWPPEG
MAB_0939|M.abscessus_ATCC_1997 FQVHSRPYGERDVDWSLNAEGTVVTGIGDDAEPAPEAAEPAEPVDAAIER
MSMEG_0408|M.smegmatis_MC2_155 FQIHSRPYGERGADWSLNAEGTVDT---AGSDPDAAADEQSDPVDEVIER
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 AAGSDDSAQ-----------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 AVPVDLGDGYEQLAERGYRYGPAFR-GLTSMWRRGDEIFAEVNLPTDAGV
MUL_2266|M.ulcerans_Agy99 AVEVENADGYQQLAERGYGYGPAFR-GLNAMWRRGDEVFAEVALPADAGV
MLBr_00135|M.leprae_Br4923 AESVDISDAYPQLAERGYAYGPAFQ-GLVAIWRRGSELFAEVVAPT--GV
MAB_0939|M.abscessus_ATCC_1997 MERMRPMELFEIFADLELAWGPTWSGSLKSLWLGEGEAIGDVLVGEELAE
MSMEG_0408|M.smegmatis_MC2_155 LERMRPQDLFETFADLELAWGPTWSGSLKSLWLGDGEAVGDILVGAELAE
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv ----------------------------------------------FNSL
Mb0413|M.bovis_AF2122/97 ----------------------------------------------FNSL
MMAR_0707|M.marinum_M ----------------------------------------------LTSL
MAV_2450|M.avium_104 STTGFGVHPVMLDAALHAVMLASDGDD---LPAGSMLVPFSWQRVSLHAA
MUL_2266|M.ulcerans_Agy99 SVSGFGIHPVMLDAALHAVILASDGADDFGVPEGSVLVPFAWQGVTLHAA
MLBr_00135|M.leprae_Br4923 VVDGMGMHPALLDAVLHALGLAIENTQ----ATTEMRLPFCWRGVSLHAG
MAB_0939|M.abscessus_ATCC_1997 QLGTEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLFLPLRYGQVTLKEK
MSMEG_0408|M.smegmatis_MC2_155 QLGSEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLFLPLRYGQVTLAEK
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 ---------------------------------------RWIRHLTARVA
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv S------AVELRNRLTAVT----------AVTLPATAIFDHPTPTELAQY
Mb0413|M.bovis_AF2122/97 S------AVELRNRLTAVT----------AVTLPATAIFDHPTPTELAQY
MMAR_0707|M.marinum_M S------AVELRNRLKTLT----------GVTLSATTAFDYPTPTQLADH
MAV_2450|M.avium_104 G------AAAVRARIVPVSPSAVSIELADGLGLPVLSVASMVARPVTDQQ
MUL_2266|M.ulcerans_Agy99 G------ASAVRARIAPAGPSAVSIELSDGLGLPVLSVASMLARPVTDQQ
MLBr_00135|M.leprae_Br4923 G------AGRVRARFTSAGADAIAVDIADSAGLPVLTVRSLVTRAMTAEQ
MAB_0939|M.abscessus_ATCC_1997 MPRRFYCRARWHESPLDSETQVFDLDYLDRDGRHLGGIREFTVKRAPREA
MSMEG_0408|M.smegmatis_MC2_155 MPRRFYCRARWHRSALDSETQVFELEFVDLGGRALGGIREFTVKRAPREA
Mflv_3393|M.gilvum_PYR-GCK ----------GTAK------------------------WLVVGDDALADQ
Mvan_3128|M.vanbaalenii_PYR-1 HRVADSPATAGTAQSSGYDPSALAELHNAWGIDGMAYPWTVASHESAPGE
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv LITQIDGHGS----------------------------------------
Mb0413|M.bovis_AF2122/97 LITQIDGHGS----------------------------------------
MMAR_0707|M.marinum_M LLSHLHHQN-----------------------------------------
MAV_2450|M.avium_104 LLAAVSNSG---PDRLFELIWSAQPSTAVQP-------------------
MUL_2266|M.ulcerans_Agy99 LRAAVSGAG---PDRLFGVDWTAQPSAELQP-------------------
MLBr_00135|M.leprae_Br4923 LRTAVTAAGGALEQGPMDLVWSPIPLSSDGHG------------------
MAB_0939|M.abscessus_ATCC_1997 LLRGLGGDATRLLYTLGWHEVAVPPVAGEGEESAASIGTWLIAGFDELAA
MSMEG_0408|M.smegmatis_MC2_155 LLRGLGGDATRLLYTLGWHEVPPPPSADD------AVGTWLIAGFDELAA
Mflv_3393|M.gilvum_PYR-GCK MR------------RLGAAVTTG---------------------------
Mvan_3128|M.vanbaalenii_PYR-1 LRTVIDLTPGSLVGLLDAAVNLGRLVDSSSPG------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------SAAAAA
Mb0413|M.bovis_AF2122/97 --------------------------------------------SAAAAA
MMAR_0707|M.marinum_M ---------------------------------------------PTGAT
MAV_2450|M.avium_104 ---------------VSLLNWGATEL-DATDTDSDSGRFAVLFESAPVAG
MUL_2266|M.ulcerans_Agy99 ---------------VPVRIWGTVES-EGDDDPGAS----VVFESVPQAG
MLBr_00135|M.leprae_Br4923 ------------GGLPSVVSWADYCAGRGNDTGVVVWEFGSASAGAQAPV
MAB_0939|M.abscessus_ATCC_1997 KVPGCIPLNRETDPELLGEVLVAAKERGVPFSGVVWRAAGPGATES--TT
MSMEG_0408|M.smegmatis_MC2_155 KVPGCVPIDRNTDLQVLGEVLSQAHARGAGFSGVVWRCATPGRKESGSAS
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 -----------------------LMVPSAAESVRFGDDATGTGGVITARS
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv NPAERIDALTDLFLQACDAGR-----DADG--------------------
Mb0413|M.bovis_AF2122/97 NPAERIDALTDLFLQACDAGR-----DADG--------------------
MMAR_0707|M.marinum_M PELDRVDALTDLFLQTCDAGR-----DDDG--------------------
MAV_2450|M.avium_104 DVVTEVYAATRAVLPVLQSWL-----ARDGAGTLVVSTRGAMTLPGEDVT
MUL_2266|M.ulcerans_Agy99 EVVAGVYAATAAVLEVLRSWL-----SRDGAGQLIITTRGAVALPDEDVT
MLBr_00135|M.leprae_Br4923 DSVAAVYSATHAALQVLQFWF-----GQDRAGTLVVLTRGAVGLVGEGIS
MAB_0939|M.abscessus_ATCC_1997 ESAARLEGEIAHLLSAVHTVQNSAQNGVKLPGGLWIVTERAVATESGEPV
MSMEG_0408|M.smegmatis_MC2_155 AESARLEAEITNLLSAVHAAQ---GPSVKLPGGLWIVTEHGVACESGEPV
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 RGRDGDDLLVDISIGGAGGAEYAHITGLRYTPVEIGTVTTSAAADPQRVA
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv -------WKMVALASNTRE-------------------------------
Mb0413|M.bovis_AF2122/97 -------WKMVALASNTRE-------------------------------
MMAR_0707|M.marinum_M -------WQIVALAANGRE-------------------------------
MAV_2450|M.avium_104 DLAGAAVWGLVRSAQTEHPGRIVLVDTDAPLDADAVAAVLAVGEPQTLLR
MUL_2266|M.ulcerans_Agy99 DLAGSAVWGLVRSAQTEHPGRIVLVDTDAQLDEHAVAAVLAAGEPQVLWR
MLBr_00135|M.leprae_Br4923 DLAAAAVWGMVRSAQSEHSGKIVLIDTDSAVD---VAVLADLGESQLLVR
MAB_0939|M.abscessus_ATCC_1997 DPVQAALWGFGRTTINEEPALRAKLVDGDGSPEAVQALARLLVTP-VDEP
MSMEG_0408|M.smegmatis_MC2_155 DPVQAALWGFGRTTINEEPALHCRLVDCDGSSEAVDLLAALLAAPGIQEP
Mflv_3393|M.gilvum_PYR-GCK --------------GPDD----------------------------LADA
Mvan_3128|M.vanbaalenii_PYR-1 HRLDWQPWTPAADAGPDTGSVAVIGDDDVAAAVRGAVAANGHAVAEIPDA
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------RMSSPVRNNVSKNVALLADGISDVVVICIP
Mb0413|M.bovis_AF2122/97 --------------------RMSSPVRNNVSKNVALLADGISDVVVICIP
MMAR_0707|M.marinum_M --------------------RMTTPVPKREWKEVVLLAGGRSDVAVVCLP
MAV_2450|M.avium_104 NGTVYTARVLGS----RAVGALLVPPEDGPWRLGMSSYGTIENLRLEPIP
MUL_2266|M.ulcerans_Agy99 NGEVYTARVHGS----RAVAGLLVPPGDGPWRLGMSTAGTFENLRLEPIP
MLBr_00135|M.leprae_Br4923 CNTVHAARLS------PAPQLLALPVGESMWRLAADGGGTLEDLVIQPCP
MAB_0939|M.abscessus_ATCC_1997 EIAVRQGKLLASRLLPWSRTGHLTVPRGSDYVLAPTERGAIDNLRITEKE
MSMEG_0408|M.smegmatis_MC2_155 EIAVRQGKLLASRLLPWARSGHLTLPRGGDFVLAPTERGAIDNLRLTETD
Mflv_3393|M.gilvum_PYR-GCK THVLYAPSTSDELG------YELFETGRALARAAAQDP-TPPKLFLLTRN
Mvan_3128|M.vanbaalenii_PYR-1 RFVVYVADVGDVDSDQDVAVRLTTEVADLVGTLAERDPRNPATLWIVTR-
TH_4458|M.thermoresistible__bu -------------------------IDRCDTGDGAGTGGTAERTVVPAPL
:
Rv0405|M.tuberculosis_H37Rv TLTVLSDQREYRDIANAMTG--RHSVYSLTLPGFDSSDALPQNADMIVET
Mb0413|M.bovis_AF2122/97 TLTVLSDQREYRDIANAMTG--RHSVYSLTLPGFDSSDALPQNADMIVET
MMAR_0707|M.marinum_M TLTVLSSPHAYLDVARAMAG--RHSVHALSLPGFDPDDALPQDREVVLEG
MAV_2450|M.avium_104 DADAPLGPGQVRVATSALAANFRDVMIALGLYPDPDAVMGIEASGVVIET
MUL_2266|M.ulcerans_Agy99 DADAALQPGHVRVALSAMAANFRDVMIALGLYPDPDAAMGVEGAGVVVET
MLBr_00135|M.leprae_Br4923 EVQAPLQAGHMRVAVAAVGVNFRDVVAALGMYPGQAPPLGAEGAGVVIEI
MAB_0939|M.abscessus_ATCC_1997 VPAPD--EGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAGIVTQL
MSMEG_0408|M.smegmatis_MC2_155 VPEPD--EGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAGTVTQL
Mflv_3393|M.gilvum_PYR-GCK AQPVEAGDRADPAQAVLWGLGRTLALEHPEIWGGVLDVDASVPAVVAARW
Mvan_3128|M.vanbaalenii_PYR-1 -GVYESATAAALPQSTLWGLAGVVGAEQPQLWGGLVDLAGEDPAGSAE--
TH_4458|M.thermoresistible__bu PAPSASAAPTVDEVLLCADQRERRELLESYLRDRVAAELG----------
:
Rv0405|M.tuberculosis_H37Rv VSNAIIDVVG----------------------------------------
Mb0413|M.bovis_AF2122/97 VSNAIIDVVG----------------------------------------
MMAR_0707|M.marinum_M AAQAILHAVG----------------------------------------
MAV_2450|M.avium_104 ASQDGRVAVGDRVMGLFPDGTGTVATTDQRLLVKVPAGWSHTAAATASVV
MUL_2266|M.ulcerans_Agy99 ASPDGRFAVGDRVVGLFPEGTGTIAITDHRLLVKIPAGWSDTAAATTSVV
MLBr_00135|M.leprae_Br4923 GPEVTGVAVGDAVMG-FLGGAGPLAVVHQQLITQMPQGWSLAEAAAVPVV
MAB_0939|M.abscessus_ATCC_1997 GEGVTGVEVGQRVYGSMQGAFGSRFNVPAQFLAPIPDGISGVEAATIPAA
MSMEG_0408|M.smegmatis_MC2_155 GAGVSGLEIGQRVYGSMQGAFASRFNVPAQFLAPIPDGIGAVEAATIPAA
Mflv_3393|M.gilvum_PYR-GCK ALAEAHAGDG----------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 ALAALLPTPV----------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv ----------------GSCRFVLSGYSSGGVLAYALCSHLSVKHQRNP--
Mb0413|M.bovis_AF2122/97 ----------------GSCRFVLSGYSSGGVLAYALCSHLSVKHQRNP--
MMAR_0707|M.marinum_M ----------------DHPHLVLAGYSSGGVLAHALGSYLAERHQRTP--
MAV_2450|M.avium_104 FATAYYALVDLADARPGQRVLVHAAAGGVGMAAVQLARHLGLEVFATASR
MUL_2266|M.ulcerans_Agy99 FATAFYALRDLASVQPGQRILVHAATGGVGMAAVQLARHWGLEVFATASK
MLBr_00135|M.leprae_Br4923 FLTALFGLADLAGIRAGESVLIHAGTGGVGMAAVQFARHWGVEIFVTASR
MAB_0939|M.abscessus_ATCC_1997 ALTVR-LSFDWAQLKPGDKVLIHAASGGVGLAAIQMAQQFGAEVFATAST
MSMEG_0408|M.smegmatis_MC2_155 ALTVR-LAFDWAQLKPGDKVLIHAASGGVGLAAIQMAQQSGAEVFATAST
Mflv_3393|M.gilvum_PYR-GCK ----------------EDQVVYRAGIRRVARLVHALPPAPTGPTTLAR--
Mvan_3128|M.vanbaalenii_PYR-1 ----------------KSVAILRDGQLRTSVLAEFTEAPARETLRCRP--
TH_4458|M.thermoresistible__bu ---------------------VLPPLLDVAAPLSTLG-------------
.
Rv0405|M.tuberculosis_H37Rv ----------------------------------LGVALIDTYLPSQ-IA
Mb0413|M.bovis_AF2122/97 ----------------------------------LGVALIDTYLPSQ-IA
MMAR_0707|M.marinum_M ----------------------------------LGVALIDTYLPSQ-IV
MAV_2450|M.avium_104 GKWDTLRDMGFDDDHLGDSRGLDFEDKFRAVTGGAGMDIVLDSLSGD-SV
MUL_2266|M.ulcerans_Agy99 GKWDTLRAMGFDEDHIGDSRSLEFEDKFRAATGGRGMDVVLDSLAGE-FV
MLBr_00135|M.leprae_Br4923 GKWDTLRDMGFDDDHIGDSRTLEFEEKFLAVTDGRGVDVVLDSLAGD-FV
MAB_0939|M.abscessus_ATCC_1997 FKRATLRKLG--VKYVYDSRTTDFADQILADTDGAGVDVVLNSLTSEGFI
MSMEG_0408|M.smegmatis_MC2_155 FKRSTLRRLG--VKYVYDSRTTDFADQILADTNGAGVDVVLNSLTSAGFV
Mflv_3393|M.gilvum_PYR-GCK ----------------------------DGAHLVIGATGNIGPGLIE-QL
Mvan_3128|M.vanbaalenii_PYR-1 ----------------------------DAAYLITGGMGVLGLLMAD-WL
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv NPSM-------------------------------NEGFSPNDTG-----
Mb0413|M.bovis_AF2122/97 NPSM-------------------------------NEGFSPNDTG-----
MMAR_0707|M.marinum_M NADN-------------------------------PDQVGVNETG-----
MAV_2450|M.avium_104 DASLRLVAPGGIFLEMGKTDIRDPEVVAAEHPGVRYRAFDLFEAGP---D
MUL_2266|M.ulcerans_Agy99 DASLRLVAPGGVFLEMGKTDIREAAVVAQQHTGVRYRAFDLFEAGP---D
MLBr_00135|M.leprae_Br4923 DASLRLLVRGGRFLEMGKTDIRDAQEIAANYPGVQYRAFDLSEAGP---V
MAB_0939|M.abscessus_ATCC_1997 EATLRATAKNGRFAEIAKRDIWTTEQMAQSRPDIAYEIVALDTVMFQEPD
MSMEG_0408|M.smegmatis_MC2_155 EATLKATAQGGRFAEIAKRDIWSHEQMAEARPDIAYEIVALDTVMFTEPD
Mflv_3393|M.gilvum_PYR-GCK AAMG----------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 ADRG----------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 RIARLLDELAAMFGEDVLRPLPVTRFDVRRAPAALRYLSQARHVGKVVMT
MUL_2266|M.ulcerans_Agy99 HIAQILAELAALFSEDVLRPLPVTTFDVRRAPAALRYLSQARHVGKVVLT
MLBr_00135|M.leprae_Br4923 RMQEMLCEVRELFDTQVLHRLPVTSWDVRCAPAAFRFMSQARHIGKVVLT
MAB_0939|M.abscessus_ATCC_1997 RIRVLLTEVSEGLAKGEWTPLPAEIYPLTEARTAFRRMQQARHIGKIVCQ
MSMEG_0408|M.smegmatis_MC2_155 RIRDLLTEVSDGMARGEWTPLPAEIYPITEARSAFRRMQQARHIGKIVLQ
Mflv_3393|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3128|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv ------------------------KGLSREVIRVARMLNRLTATR-----
Mb0413|M.bovis_AF2122/97 ------------------------KGLSREVIRVARMLNRLTATR-----
MMAR_0707|M.marinum_M ------------------------ALFSRRVTSMARELDQLNATR-----
MAV_2450|M.avium_104 MP----DAWTAGTVLITGATGMAGSAVARHVVTRHGARNLVLVSRRGLDA
MUL_2266|M.ulcerans_Agy99 MP----DAWAAGTVLITGGTGMAGSALARHVVAHHGVRQLVLVSRRGPDA
MLBr_00135|M.leprae_Br4923 MPSALADGLAEGTVLITGASGAIGGVLARHMVSAYGVRHLVLASRRGDRA
MAB_0939|M.abscessus_ATCC_1997 MPNP--LAPRPDRTYLITGGLGAIGLHTAAYLAQLGAGDIVLTSRRAPDT
MSMEG_0408|M.smegmatis_MC2_155 VPKP--LQPQQDRSYLITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDE
Mflv_3393|M.gilvum_PYR-GCK -----------------------AGTVVAVSRNPGTRLDELTAR------
Mvan_3128|M.vanbaalenii_PYR-1 -----------------------ARRVVLAGRTPLPPRRDWDDESIDADT
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------LTAAATYAAIFQAWEP-GRSMAP----VLN
Mb0413|M.bovis_AF2122/97 --------------------LTAAATYAAIFQAWEP-GRSMAP----VLN
MMAR_0707|M.marinum_M --------------------LTAAASYAALFGTWEP-VVSAVP----LLN
MAV_2450|M.avium_104 PDAAELVAELTAAGAHAEVVACDAADREALAKVIAD-IPMQHP-LTGVIH
MUL_2266|M.ulcerans_Agy99 PGAAELAEELSAFGAQVQVVACDAADRAALAKLIAD-IPMQHP-LSAVIH
MLBr_00135|M.leprae_Br4923 EGAVELAAELVGAGAKIQVVACDVADNDAVRGLFAQ-LSREFPPVRGVIH
MAB_0939|M.abscessus_ATCC_1997 DAQRVIGEITERSKTRIHVFTADVGAESEVAGLLER-IRAELPPLAGVAH
MSMEG_0408|M.smegmatis_MC2_155 SAQRAIDEITERHKCRIHTYAADVGDEAQVADLLAR-IRAELPPLAGIAH
Mflv_3393|M.gilvum_PYR-GCK ---------LAATGTTVVTVAADASDESSLRPVFER-FGADLPPLKGVYL
Mvan_3128|M.vanbaalenii_PYR-1 RHKIAAIRALELRGVSVDTVALDVGSREALTAVLDKRDGDGAPPIRGVIH
TH_4458|M.thermoresistible__bu ---------------------IDSLTAAELRARVERDLGIVIPVAQLLNG
: * :
Rv0405|M.tuberculosis_H37Rv IVAKDRIATVENLREERINRWRTAAAEAAYSVAEVP-----------GDH
Mb0413|M.bovis_AF2122/97 IVAKDRIATVENLREERINRWRTAAAEAAYSVAEVP-----------GDH
MMAR_0707|M.marinum_M MIAMDETAACERVRAERINRWRVATAEASYSVVEVP-----------GDH
MAV_2450|M.avium_104 AAGVLDDAVVTSLTPQRIDTVLRAKVDAAWNLHELTRDLDVGAFVMFSSI
MUL_2266|M.ulcerans_Agy99 TAGALDDAVVTSLTPERIETVLRAKVDAAWNLHELTRDMDLSAFVMFSSM
MLBr_00135|M.leprae_Br4923 AAGVLDDGAITSLTPDRVDTVLRAKVDAAWNLHEATRDLDLLMFVLCSSI
MAB_0939|M.abscessus_ATCC_1997 LAGVLDDALLGQQSVERFRTTLAPKAFGAEYLDRLTKGDDLDFFIVSSSV
MSMEG_0408|M.smegmatis_MC2_155 LAGVLDDALLSAQNPERFRTTLAPKAYGASHLDRLTRDDDLDFFIVSSSV
Mflv_3393|M.gilvum_PYR-GCK AAMAGGPVTLAEMTHEDVVAMFRPKLDAAAAVHTLSLSHPVEQFVLFSSI
Mvan_3128|M.vanbaalenii_PYR-1 AAGMTEAQLLTEIEADRVHRTVWPKIAGAKVLDELFPPGSLDFLYLAASA
TH_4458|M.thermoresistible__bu PSVSDLAEWISTTMVGFGSTTPEPESAGVPGRSRPPDGAVASGSGDGGRW
. . .
Rv0405|M.tuberculosis_H37Rv FGMMSTSSEAIATEIHDWISGLVRGPHR----------------------
Mb0413|M.bovis_AF2122/97 FGVMSTSSEAIATEIHDWISGLVRGPHP----------------------
MMAR_0707|M.marinum_M FDMITTSSDATTTALHGWISGLIRAG------------------------
MAV_2450|M.avium_104 AGLAGASGQGNYAAGNSFLDGLAAHRRAHGLPAISLGWGLWDQASAMTGG
MUL_2266|M.ulcerans_Agy99 AGLVGSSGQGNYAAANSFLDGLAVHRQAHGLPAISLGWGLWDQASNMTGG
MLBr_00135|M.leprae_Br4923 AATVGSPGQGNYSAANAFLDGLAAYRQAAGLAGTSLAWGLWEQPGGMNAH
MAB_0939|M.abscessus_ATCC_1997 SSLFGSPGQSNYATANALLDGLIAQRRAQGLPATGINFGPWGQGGMASSE
MSMEG_0408|M.smegmatis_MC2_155 SSLFGSPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGGMASSE
Mflv_3393|M.gilvum_PYR-GCK SGVLGSRWLAHYAATTTFLDTFAFARRAAGLPASAINWGLWKSLADAQTG
Mvan_3128|M.vanbaalenii_PYR-1 GAVFGIPGQGAYAAGNAYLDALARSRHHRGDNTVSLDWVAWQGLGFGS--
TH_4458|M.thermoresistible__bu IELLNQMPEVSDDTVDELLRQLLAAGENHDDTQLH---------------
: :
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 LGAADLARFGRDGIVAMSSQEALELMDTALIVDEPFLLPAHIDLAALRVK
MUL_2266|M.ulcerans_Agy99 LAAVDFKRFARDGIVAMSSDEALGLLDTAMVLGEPFMLPAHIDFAALRVK
MLBr_00135|M.leprae_Br4923 LSSRDLARISRSGLAPMNPAQALELFDAALVIDHPFMVTALLDRAALDAQ
MAB_0939|M.abscessus_ATCC_1997 AATANIS------------AQGLIPLDPSAALAALAEVVANGTGQATILK
MSMEG_0408|M.smegmatis_MC2_155 AATANIT------------AQGLIPLDPSAALHALAEVIANGSGQATVLK
Mflv_3393|M.gilvum_PYR-GCK FEA---QATHESGLEPMDDAVAITALQAFVGPQAPVRGTVVAADWPRLAA
Mvan_3128|M.vanbaalenii_PYR-1 ------------------EAQVVVSELERVGSRPVVP--------AEAFA
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 FDGGTLPPMFVDLINAPTRRQVDDSLAAAKSKSALLQRLEGLPEDEQQAV
MUL_2266|M.ulcerans_Agy99 FDGGTLPPMFVDLINAPTRRQVDDSLAAAKSKSALLQRLEGLPEDEQHAI
MLBr_00135|M.leprae_Br4923 AQAGALPPLFSRLVRRSRRRQIEDPGDATQSKLALVQRLQGLAANRQLEL
MAB_0939|M.abscessus_ATCC_1997 ANWQRAAKVLGSSRPPILDLVLPSAVGEVTGDSELLKQLMEIPVPQRAGF
MSMEG_0408|M.smegmatis_MC2_155 ANWQRAAKVLGSARPPILDLVLPSAAGEATGDSELLKQLMEIPIPQRAGF
Mflv_3393|M.gilvum_PYR-GCK AYHTRAQLHILDDLLAEEGTAASGPALTGDTKFR--QELKDRDPEQRRDM
Mvan_3128|M.vanbaalenii_PYR-1 AWDFVTRFDVAQVVMAPMQSAEDAAAVTADTHRAPTRDWTAMAPDELLAE
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 LLDLVRSNIATVLGSSSPEAIHPDRAFQELGFDSLTAVEMRNRLKAATG-
MUL_2266|M.ulcerans_Agy99 LLNLVRSHIATVLGNSSPDAIDPDRAFQELGFDSLTAVEMRNRLKSATG-
MLBr_00135|M.leprae_Br4923 LVGVVCLQAAAVLGRPSPEDIDPNTKFQDLGFDSLTAVELRNRLKSATG-
MAB_0939|M.abscessus_ATCC_1997 VTEFLQREVQNFLRLAQPPAATSR--FLDLGTDSLMAIELRNRLHSQFGG
MSMEG_0408|M.smegmatis_MC2_155 VTEFLQREVQNFLRLASPPAASSR--FLDLGTDSLMAIELRNRLHSQFGG
Mflv_3393|M.gilvum_PYR-GCK LTDFVISQVAAAMGLASAHTLDPGVGFFQFGMDSLMSVTLQRSLSESLG-
Mvan_3128|M.vanbaalenii_PYR-1 LQDGLRGILATELRLPESD-VHTDRPFAEMGLNSVMAMSIRREVERLVG-
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 -LALSPTLIFDYPNSAALAGYMYRELVGTSEQP-TAAAAPGEAEIQRVVG
MUL_2266|M.ulcerans_Agy99 -LALSPTLIFDYPNSAALAGYMHRELVGASPQSDTTAEAPGEAELQRVVA
MLBr_00135|M.leprae_Br4923 -LTLPPTVIFDHPTPTAVAEYVAQQMLKS---------------------
MAB_0939|M.abscessus_ATCC_1997 KFTINATAVFDYPTIGGLAEYLVG--------------------------
MSMEG_0408|M.smegmatis_MC2_155 KFTINATAVFDYPTIGGLAEYLVG--------------------------
Mflv_3393|M.gilvum_PYR-GCK -ETLPASVVFDYPTVEALTDYLASVLPEI---------------------
Mvan_3128|M.vanbaalenii_PYR-1 -LELSATMLFNHPTIESFASYLAQQL------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb0413|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
MAV_2450|M.avium_104 SIPVKRLRQAGVLELLLALANESTGTAQSATPAVTTEKDIADMDLDDLVN
MUL_2266|M.ulcerans_Agy99 SIPVKRLRQAGVLELLLALANETGGNGQAAVTAETSEEDLADMDLDALVN
MLBr_00135|M.leprae_Br4923 ------------------RPAESGDETSQAVEPKVEEVSVHA--------
MAB_0939|M.abscessus_ATCC_1997 -----------------QLPDADAESAEAPPAVESAEAESGAGPAAASDA
MSMEG_0408|M.smegmatis_MC2_155 -----------------QLPDAEAPETA----------------------
Mflv_3393|M.gilvum_PYR-GCK ----------------IETAGTEGGDVISDEADDTYDDLAEDELLARLSE
Mvan_3128|M.vanbaalenii_PYR-1 ------------------APETGGDDEVADDSGGSLLDSLFDSVEN----
TH_4458|M.thermoresistible__bu --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv ---------
Mb0413|M.bovis_AF2122/97 ---------
MMAR_0707|M.marinum_M ---------
MAV_2450|M.avium_104 AALLDDDDE
MUL_2266|M.ulcerans_Agy99 AAFMNDDE-
MLBr_00135|M.leprae_Br4923 ---------
MAB_0939|M.abscessus_ATCC_1997 VSELKE---
MSMEG_0408|M.smegmatis_MC2_155 ---------
Mflv_3393|M.gilvum_PYR-GCK RLS------
Mvan_3128|M.vanbaalenii_PYR-1 ---------
TH_4458|M.thermoresistible__bu ---------