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RVRISGHHIDAVRAVAIEDVVAEVAGVHAVQAYPRSASVVIWYAPEDCDTAAVLSAISDAQYIPAELVPA RAPHSSNPSNTGVVQKITGGILRLLGLSPDTDTRDTAGEGSCHQPAASCHGAPAADAKGEQRKWLRRVWL AAPLGLVSMAAPMLFGASWAGWLAFAATVPVQFVAGWPFLKGAVQQARAGSAGMDTLIALGTLTAFAYST YGLFAGGPLFFDTAALIIAFVVLGRYFEARATGKTREAISTLLEMGAKEACLLIDGQEVLVPVEQVQVGD LLLVRPGEKIPVDGEITDGRAAVDESMLTGESVPVEKTVGDRVAGATVNTDGLLTVRATAVGADTALAQI VRLVEQAQGGKAPVQRLADRVSAVFVPAVLGVAALTFAGWALIAANPIAGMTAAVSVLIIACPCALGLAT PTAIIVGTGRGAEMGILVKGGEVLEASKKIDTVVFDKTGTLTRGKMQLTDVIPDKRQKSDLVLGLAAAVE SGSEHPVGAAIVAGARERELEIPAATSFTNLAGHGVRAEVDGQVVLVGRRKLVDENDLRLSDHLAAVAAE LEEQGRTAVFVGRGDRVVGVLAVADTIKDDAVEVVRQLHEMGLQVAMITGDNARTAAAIAGQVGIDRVLA EVLPEDKVNEVRRLQDEGRLVAMVGDGVNDAPALVQADLGIAIGTGTDVAIEASDITLMSGRLDGVVRSL QLSRQTLRTIHQNLGWAFGYNTAAIPLAAFGLLNPVVAGAAMGLSSVSVVTNSLRLRRFGRDT*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_2536 | - | - | 100% (764) | metal cation transporter p-type ATPase |
M. marinum M | MMAR_1431 | zntA | 0.0 | 81.14% (774) | cation transport ATPase, ZntA |
M. marinum M | MMAR_4876 | ctpV | 0.0 | 76.68% (776) | metal cation transporter p-type ATPase, CtpV |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0994 | ctpV | 0.0 | 78.46% (766) | metal cation transporter P-type ATPase CtpV |
M. gilvum PYR-GCK | Mflv_2244 | - | 1e-177 | 51.37% (658) | heavy metal translocating P-type ATPase |
M. tuberculosis H37Rv | Rv0969 | ctpV | 0.0 | 78.59% (766) | metal cation transporter P-type ATPase CtpV |
M. leprae Br4923 | MLBr_01987 | ctpA | 1e-148 | 46.56% (640) | putative cation-transporting ATPase |
M. abscessus ATCC 19977 | MAB_3984c | - | 1e-160 | 48.73% (669) | putative metal transporter ATPase |
M. avium 104 | MAV_5246 | - | 1e-165 | 47.90% (691) | copper-translocating P-type ATPase |
M. smegmatis MC2 155 | MSMEG_5014 | - | 1e-179 | 50.51% (693) | copper-translocating P-type ATPase |
M. thermoresistible (build 8) | TH_4361 | - | 0.0 | 51.98% (681) | PUTATIVE heavy metal translocating P-type ATPase |
M. ulcerans Agy99 | MUL_0423 | ctpV | 0.0 | 75.90% (776) | metal cation transporter p-type ATPase, CtpV |
M. vanbaalenii PYR-1 | Mvan_4449 | - | 1e-178 | 52.15% (650) | heavy metal translocating P-type ATPase |
CLUSTAL 2.0.9 multiple sequence alignment Mb0994|M.bovis_AF2122/97 --MRVCVTGFNVDAVRAVAIEETVSQVTGVHAVHAYPRTASVVIWYSPEL Rv0969|M.tuberculosis_H37Rv --MRVCVTGFNVDAVRAVAIEETVSQVTGVHAVHAYPRTASVVIWYSPEL MMAR_2536|M.marinum_M --MRVRISGHHIDAVRAVAIEDVVAEVAGVHAVQAYPRSASVVIWYAPED MUL_0423|M.ulcerans_Agy99 --MRVHANGFAIDATRAAAIEESVGRVGGVRAVRAYPRTASVVIWYSPAH Mflv_2244|M.gilvum_PYR-GCK -------------------MNTLELSIGGMTCASCAAR---VEKKLNKLD Mvan_4449|M.vanbaalenii_PYR-1 -------------------MNTIELSIGGMTCASCAAR---VEKKLNKLD MSMEG_5014|M.smegmatis_MC2_155 ---------------MTTATGHVELQIGGMTCASCAAR---IERKLNKLD MAV_5246|M.avium_104 MSTPPRHIDEGTFPDHTASTARIELEITGMTCASCAAR---IEKKLNKLD TH_4361|M.thermoresistible__bu --------------MNTGGMNTVTLTVGGMTCASCAAR---VEKRLNRID MAB_3984c|M.abscessus_ATCC_199 ------------METTNTGMETTDLRLHGMTCASCASR---VEKGLNKIT MLBr_01987|M.leprae_Br4923 -----------------------------MRAPNGWNN------LPNKLS : . . Mb0994|M.bovis_AF2122/97 GDTAAVLSAITKAQHVPAELVPARAPHSAGVRGVGVVRKITGGIRRMLS- Rv0969|M.tuberculosis_H37Rv GDTAAVLSAITKAQHVPAELVPARAPHSAGVRGVGVVRKITGGIRRMLS- MMAR_2536|M.marinum_M CDTAAVLSAISDAQYIPAELVPARAPHSSNPSNTGVVQKITGGILRLLG- MUL_0423|M.ulcerans_Agy99 CDTAAIVSAIAEAEHAGDASAPAPAARVAGIADGGVVGRVIGGLARALLG Mflv_2244|M.gilvum_PYR-GCK GVTATVNYATEKARVEFGDNVST-DQLVSAVESAGYQAALPEP------- Mvan_4449|M.vanbaalenii_PYR-1 GVTATVNFATEKARVAFGDEVSP-GQLVSAVESAGYQAELPER------- MSMEG_5014|M.smegmatis_MC2_155 GVTASVNYATEKASVEVAGEVSP-ETLIEVVETAGYTAHLPAP------- MAV_5246|M.avium_104 GVTATVNYATEKAAVSAPASYDP-QTLITEIENAGYAAAVATP------- TH_4361|M.thermoresistible__bu GVVATVNFATEQATVRYPDHVDP-ADLIAAIEATGYTASLPAPQRDTGGA MAB_3984c|M.abscessus_ATCC_199 GVNARVNLALESARVEHDGSVTG-EDLVKAVESVGYTAQVVGGSHQDAHA MLBr_01987|M.leprae_Br4923 DFSTLVNSATRVAAINLSEVTQT-AEVCEAVRRAALCTDGGEALQR---- : : * * . Mb0994|M.bovis_AF2122/97 ---------RPPGVDKPLKASRCGGRPRGPVRGSASWPGEQNRRERRTWL Rv0969|M.tuberculosis_H37Rv ---------RPPGVDKPLKASRCGGRPRGPVRGSASWPGEQNRRERRTWL MMAR_2536|M.marinum_M ---------LSPDTDT--RDTAGEGSCHQPAASCHGAPAADAKGEQRKWL MUL_0423|M.ulcerans_Agy99 MRTDDNDDDPPPEIARLRAALDRIGYSPEQDTATQLSPSEQARSGIRFWS Mflv_2244|M.gilvum_PYR-GCK -------------------------PNPPD-----VEPADPTAALRRRLI Mvan_4449|M.vanbaalenii_PYR-1 -------------------------PDEPA-----EPTDDPTAALKRRLL MSMEG_5014|M.smegmatis_MC2_155 -------------------------PQPETGGTEQDPEDRATDALRTRLL MAV_5246|M.avium_104 -------------------------SPPRD--------DPELASLRRRLV TH_4361|M.thermoresistible__bu -------------------------PAGAATGAAGDDHDAEAERWRRRLT MAB_3984c|M.abscessus_ATCC_199 G------------------------DHDGHDPHDHMNHDVPDDQLKSRLI MLBr_01987|M.leprae_Br4923 ----------------------------------RQADADNARYLLIRLA Mb0994|M.bovis_AF2122/97 PRVWLALPLGLLA-LGSSMFFGAYPWAGWLAFAATLPVQFVAGWPILRGA Rv0969|M.tuberculosis_H37Rv PRVWLALPLGLLA-LGSSMFFGAYPWAGWLAFAATLPVQFVAGWPILRGA MMAR_2536|M.marinum_M RRVWLAAPLGLVS-MAAPMLFGAS-WAGWLAFAATVPVQFVAGWPFLKGA MUL_0423|M.ulcerans_Agy99 RRAWLAWPLGLLA-SGLTMFFGAYPWAGWLAFAATIPVQFIAGWPFLVGA Mflv_2244|M.gilvum_PYR-GCK ICVALSVPVIAMA-MAPPLQFTYW---QWLSLTLAAPVVVWGAWPFHRAT Mvan_4449|M.vanbaalenii_PYR-1 ICVALSVPVIAMA-MVPVLQFTYW---QWLSLTLAAPVVVWGAWPFHQAA MSMEG_5014|M.smegmatis_MC2_155 VSAVLTVPVIAMA-MVPALQFTNW---QWLSLTLAAPVVVWGALPFHRAA MAV_5246|M.avium_104 TAIALAGPVIAVA-MIPALQFQHW---HWAALALTAPVVGWCGRPFHAAA TH_4361|M.thermoresistible__bu ISAALSIPVVVLS-MIPALQFTHW---QWLALTLTSPVVVWGAWPFHRAA MAB_3984c|M.abscessus_ATCC_199 GSLILAIPVVVIS-MAMPLHFSGW---EILVAALTTPILLWGGYPFHRAA MLBr_01987|M.leprae_Br4923 VAAALFVPLAHLSVMFAVLPSTHFPGWEWMLTALAIPVVTWAAWPFHRVA * *: :: : : : *: . *: : Mb0994|M.bovis_AF2122/97 VQQARALTSNMDTLIALGTLTAFVYSTYQLFAG----------------- Rv0969|M.tuberculosis_H37Rv VQQARALTSNMDTLIALGTLTAFVYSTYQLFAG----------------- MMAR_2536|M.marinum_M VQQARAGSAGMDTLIALGTLTAFAYSTYGLFAG----------------- MUL_0423|M.ulcerans_Agy99 VQQARARSANMNTLISLGTLTAFIYSTYQLFAG----------------- Mflv_2244|M.gilvum_PYR-GCK WANLRHGTATMDTLISVGTLAAFGWSIYALFWGTAGVPGMTHPFELTIAR Mvan_4449|M.vanbaalenii_PYR-1 WTNLRHGTATMDTLISIGTLAALGWSIYALFWGTAGIPGMTHPFELTIAR MSMEG_5014|M.smegmatis_MC2_155 WLNLRHGTATMDTLISMGTLAAFGWSLYALFWGTAGVPGMTHPFSLVGSR MAV_5246|M.avium_104 WANLKHGVTTMDTLISIGTLAAFLWSLYALVLGAADRPGMRHDFELTVGH TH_4361|M.thermoresistible__bu VANLRHGTATMDTLISLGVTAAYLWSLWALFFTAAGMPGMTMTFTLLPAD MAB_3984c|M.abscessus_ATCC_199 LVNARHGASTMDTLVSLGTIAAYLWSLWVLFANAGHT------------- MLBr_01987|M.leprae_Br4923 IHNARYHGASMETLISTGITAATIWSLYTVFGHHQSTEHRGVWRALLG-- : : : *:**:: * :* :* : :. Mb0994|M.bovis_AF2122/97 ----------GPLFFDTSALIIAFVVLGRHLEARATGKASEAISKLLELG Rv0969|M.tuberculosis_H37Rv ----------GPLFFDTSALIIAFVVLGRHLEARATGKASEAISKLLELG MMAR_2536|M.marinum_M ----------GPLFFDTAALIIAFVVLGRYFEARATGKTREAISTLLEMG MUL_0423|M.ulcerans_Agy99 ----------GPLFFDTAALIIAFVVLGRYFEATAHGKTREAISKLLDMG Mflv_2244|M.gilvum_PYR-GCK ------TDGSGNIYLEAAAGVTTFILAGRYFEARAKRRAGAALRALLELG Mvan_4449|M.vanbaalenii_PYR-1 ------TDGTSNIYLEAAAGVTTFILAGRYFEARAKRRAGAALRALLELG MSMEG_5014|M.smegmatis_MC2_155 ------TDGAGNIYLEVAAGVTTFILAGRYFEAKSKRRASAALRALMELG MAV_5246|M.avium_104 GAHVSHVAAPCHVYFEVAAGVTLFVLAGRYFERRSKRTAGAALRALLALG TH_4361|M.thermoresistible__bu -------TGEPHIYLEVAAAVTTFIIAGRYFEARAKRQSGAALRALLDMG MAB_3984c|M.abscessus_ATCC_199 -------HGDVHVYFEVVAAVTVFLLAGRFAESRAKRSAGSALRALLSLG MLBr_01987|M.leprae_Br4923 ---------SDAIYFEVAAGITVFVLAGKYYTARAKSHASIALLALAALS ::::. * : *:: *:. : : *: * :. Mb0994|M.bovis_AF2122/97 AKEATLLV-DGQELLVPVDQVQVGDLVRVRPGEKIPVDGEVTDGRAAVDE Rv0969|M.tuberculosis_H37Rv AKEATLLV-DGQELLVPVDQVQVGDLVRVRPGEKIPVDGEVTDGRAAVDE MMAR_2536|M.marinum_M AKEACLLI-DGQEVLVPVEQVQVGDLLLVRPGEKIPVDGEITDGRAAVDE MUL_0423|M.ulcerans_Agy99 AKETRLIV-DGEEHLVPVDRVQVGDLVRVRPGEKIPVDGEVIDGRAAVDE Mflv_2244|M.gilvum_PYR-GCK VRDVTVRR-GAAEHRIPIDQLRVDDEFVVRPGEKVAADGIIVEGASAVDA Mvan_4449|M.vanbaalenii_PYR-1 AREVTVRR-GGAEQRIPIEQLVIGDEFVVRPGEKIAADGTVVEGASAVDA MSMEG_5014|M.smegmatis_MC2_155 AKDVAILR-NGAEQRIPIDQLGVGDEFVVRPGEKIATDGVVVDGSSAVDA MAV_5246|M.avium_104 AKDVAVLR-AGAETRIPIERLAVGDEFVVRPGERIATDGIVVAGSSAVDA TH_4361|M.thermoresistible__bu ANDVAVLR-DGAEKRVPIGELHVGDVFVVRPGEKIATDGEVVAGNSAVDA MAB_3984c|M.abscessus_ATCC_199 AKDVAVLR-GGHETRIPVDQLAVGDEFVVRPGERVATDGEVIEGHSALDT MLBr_01987|M.leprae_Br4923 AKDAAVLQPDGSEMVIPANELNEQQRFVVRPGQTIAADGLVIDGSATVSM ..:. : . * :* .: : . ****: :..** : * :::. Mb0994|M.bovis_AF2122/97 SMLTGESVPVEKTAGDRVAGATVNLDGLLTVRATAVGADTALAQIVRLVE Rv0969|M.tuberculosis_H37Rv SMLTGESVPVEKTAGDRVAGATVNLDGLLTVRATAVGADTALAQIVRLVE MMAR_2536|M.marinum_M SMLTGESVPVEKTVGDRVAGATVNTDGLLTVRATAVGADTALAQIVRLVE MUL_0423|M.ulcerans_Agy99 SMLTGESVPVEKGVGDWVAGATVNTDGLLTVRATAVGADTALAQIVRLVE Mflv_2244|M.gilvum_PYR-GCK SMLTGESVPLEVKPGDRVVGATVNVDGRLVVRAERVGADTQLAQMARLVE Mvan_4449|M.vanbaalenii_PYR-1 SMLTGESVPEEVQPGDQVVGATVNVDGRLVVRADRVGSDTQLAQMARMVE MSMEG_5014|M.smegmatis_MC2_155 SMLTGESVPVEVGPGDQVVGATVNVGGRLVVRANRIGSDTQLAQMARLVE MAV_5246|M.avium_104 AMLTGESVPVEVGVGDGVTGGTVNAGGRLVVRATGIGDDTQLARMAQLVE TH_4361|M.thermoresistible__bu SMLTGESVPVEVGPGDQVVGATVNVGGHLQVRATRVGADTQLAQMARLVT MAB_3984c|M.abscessus_ATCC_199 STMTGESVPMEVTVGGPVLGGYVNTHGRIVVRANKVGADTQLARMARLVS MLBr_01987|M.leprae_Br4923 SPITGEAKPVRVNPGAQVIGGTVVLNGRLIVEAAAVGDETQLAGMVRLVE : :***: * . * * *. * * : *.* :* :* ** :.::* Mb0994|M.bovis_AF2122/97 QAQGDKAPVQRLADRVSAVFVPAVIGVAVATFAGWTLIAANPVAG-MTAA Rv0969|M.tuberculosis_H37Rv QAQGDKAPVQRLADRVSAVFVPAVIGVAVATFAGWTLIAANPVAG-MTAA MMAR_2536|M.marinum_M QAQGGKAPVQRLADRVSAVFVPAVLGVAALTFAGWALIAANPIAG-MTAA MUL_0423|M.ulcerans_Agy99 EAQGGKAPVQRLADRVSAVFVPVVVRIAAATFAGWTLLAANPVAG-MTAA Mflv_2244|M.gilvum_PYR-GCK DAQNGKAQAQRLADRISGVFVPVVLGLAVATLGFWIG-SGYPVAAAFTAA Mvan_4449|M.vanbaalenii_PYR-1 DAQNGKAQAQRLADRISGVFVPIVIALSVATLGFWIG-SGFPVAAAFTAA MSMEG_5014|M.smegmatis_MC2_155 DAQSGKAQAQRLADRVSAVFVPIVIALAVATLGFWLG-TGGSVAAAFTAA MAV_5246|M.avium_104 RAQSGKADAQRLADRVSGVFVPVVLLLAVATLAGWLA-AGGTLATALTAA TH_4361|M.thermoresistible__bu EAQSGKAEVQRLADRVSAVFVPIVIALSALTLAGWLLLTDAPVSAAFTAA MAB_3984c|M.abscessus_ATCC_199 DAQTGKAQVQRLADRVSSVFVPVVLAISALTFVAWAA-LGNSLASAFTAA MLBr_01987|M.leprae_Br4923 QAQQQNANAQRLADRIASVFVPCVFAVAALTAVGWLI-AGSGPDRVFSAA ** :* .******::.**** *. ::. * * ::** Mb0994|M.bovis_AF2122/97 VAVLIIACPCALGLATPTAIMVGTGRGAELGILVKGGEVLEASKKIDTVV Rv0969|M.tuberculosis_H37Rv VAVLIIACPCALGLATPTAIMVGTGRGAELGILVKGGEVLEASKKIDTVV MMAR_2536|M.marinum_M VSVLIIACPCALGLATPTAIIVGTGRGAEMGILVKGGEVLEASKKIDTVV MUL_0423|M.ulcerans_Agy99 VSVLIIACPYALGLATPTAIIVGTGRGADMGILVKGGEVLEASKKIDTVV Mflv_2244|M.gilvum_PYR-GCK VAVLIIACPCALGLATPMALMVGTGRGAQLGILIKGPEVLESTRRVDTVI Mvan_4449|M.vanbaalenii_PYR-1 VAVLIIACPCALGLATPTALMVGTGRGAQLGILIKGPEVLEDTRRVDTVI MSMEG_5014|M.smegmatis_MC2_155 VAVLIIACPCALGLATPTALLVGTGRGAQLGILIKGPEVLESTRRVDTIV MAV_5246|M.avium_104 VAVLIIACPCALGLATPTALLVGTGRAAQLGVLIKGPEVLETTRAVDTVV TH_4361|M.thermoresistible__bu VAVLIIACPCALGLATPTALLVGTGRGAQLGILIKGPQVLESTRRIDTVV MAB_3984c|M.abscessus_ATCC_199 VAVLIIACPCALGLATPTAILVGTGRGAQLGVLIKGPEVLENVKDIDTVV MLBr_01987|M.leprae_Br4923 IAVLVIACPCALGLATPTAMMVASGRGAQLGILLKGHESFEATRAVDTVV ::**:**** ******* *::*.:**.*::*:*:** : :* : :**:: Mb0994|M.bovis_AF2122/97 FDKTGTLTRARMRVTDVIAGQRR---QPNQVLRLAAAVESGSEHPIGAAI Rv0969|M.tuberculosis_H37Rv FDKTGTLTRARMRVTDVIAGQRR---QPDQVLRLAAAVESGSEHPIGAAI MMAR_2536|M.marinum_M FDKTGTLTRGKMQLTDVIPDKRQ---KSDLVLGLAAAVESGSEHPVGAAI MUL_0423|M.ulcerans_Agy99 FDKTGTLTRAQMELTDVIAGKRR---QPDVVLRIAAAVESGSEHPIGAAI Mflv_2244|M.gilvum_PYR-GCK VDKTGTVTTGDMTLVDVFAADGE---QPDEVLRMAGAVESPSEHPIAAAI Mvan_4449|M.vanbaalenii_PYR-1 LDKTGTVTTGSMTLVDVFAAEGE---QPDEVLRVAGAVESSSEHPIARAI MSMEG_5014|M.smegmatis_MC2_155 LDKTGTITTGSMTLLDVVVADGE---DRDDVLRVAAAVEDASEHPIARAI MAV_5246|M.avium_104 LDKTGTVTTGAMTVLDVVAADGT---DRATLLRYAGALEAASEHPIAHAI TH_4361|M.thermoresistible__bu LDKTGTVTTGQMSVTSVHVADGL---SETELLRLAGAVEHASEHPIARAV MAB_3984c|M.abscessus_ATCC_199 LDKTGTVTTGVMSVVEVRRSIGSGVADADEILRIAASVESASEHPVARAI MLBr_01987|M.leprae_Br4923 FDKTGTLTTGQLKVSAVTAAPGW---QANEVLQMAATVESASEHAVALAI .*****:* . : : * . :* *.::* ***.:. *: Mb0994|M.bovis_AF2122/97 VAAAHERGLAIPAANAFTAVAGHGVRAQVNGGPVVVGRRKLVDEQHLVLP Rv0969|M.tuberculosis_H37Rv VAAAHERGLAIPAANAFTAVAGHGVRAQVNGGPVVVGRRKLVDEQHLVLP MMAR_2536|M.marinum_M VAGARERELEIPAATSFTNLAGHGVRAEVDGQVVLVGRRKLVDENDLRLS MUL_0423|M.ulcerans_Agy99 VAGARERELEVPPATEFTNLAGHGVRGEVGGKSVLVGRRKLVDEQHLRLP Mflv_2244|M.gilvum_PYR-GCK AGGARDKLGDLPAVDGFANLRGLGVEGDVEGRRLTLGRLRLLSDRSFEIP Mvan_4449|M.vanbaalenii_PYR-1 AAGAQEKFGELPAVTAFTNLRGLGVSGQVDGRAVLLGRLRLLADRSHEIP MSMEG_5014|M.smegmatis_MC2_155 AAGARERTGELPAVEGFANIEGLGVQGTVEGRAVVVGRPRLFGDPEKSLP MAV_5246|M.avium_104 ARDAKAELGPLPTPTGFRAVGGGGVHGRVDGHAVAIGRPSWLAERGLRPD TH_4361|M.thermoresistible__bu ATHAAQTVPPLPEVSDFENHGGNGVSGRVDGHDVRVGRLAWLG---LSAG MAB_3984c|M.abscessus_ATCC_199 VAAAASARLTLSPVTNFRNEPGVGVSGVVDGQEVSI-------------- MLBr_01987|M.leprae_Br4923 AASTTHR----EPVANFRAVPGHGVSGTVAERAVRVGKPSWIASR--CNS . : * * ** . * : : Mb0994|M.bovis_AF2122/97 DHLAAAAVEQEERGRTAVFVGQDGQVVGVLAVADTVKDDAADVVGRLHAM Rv0969|M.tuberculosis_H37Rv DHLAAAAVEQEERGRTAVFVGQDGQVVGVLAVADTVKDDAADVVGRLHAM MMAR_2536|M.marinum_M DHLAAVAAELEEQGRTAVFVGRGDRVVGVLAVADTIKDDAVEVVRQLHEM MUL_0423|M.ulcerans_Agy99 EQLAAAAADLEERGRTAVYVGQDGQVVGVLAVADTVKDDAADVVSQLHAM Mflv_2244|M.gilvum_PYR-GCK DDLASAVARAEAGGSTAVTVGWDGRARGVLMVADAVKPTSAEAISLLKRA Mvan_4449|M.vanbaalenii_PYR-1 SELEVAVARAESDGRTAVVVGWDGQARGVLMVADAVKPTSAEAISLLKRL MSMEG_5014|M.smegmatis_MC2_155 RKLADAMEAAQAQGRTAVVVGWDGTARGVLVVADAVKATSAEAIGQLRKL MAV_5246|M.avium_104 AALAAAAARAEHDGKTVVAVGWDGRARGILALADTVKPSSAAAVRQFTRL TH_4361|M.thermoresistible__bu DRLRNAAAQAEAAGHTPVWVAVDGRIAGVIVVSDTVKDHAAEAIAELRAL MAB_3984c|M.abscessus_ATCC_199 --------EAIEGQNTTAAVSWGGLRRGEIEVADTVKPSSRRAIDELKAM MLBr_01987|M.leprae_Br4923 TTLVTARRNAELRGETAVFVEIDGEQCGVIAVADAVKASAADAVAALHDR * . * .. * : ::*::* : .: : Mb0994|M.bovis_AF2122/97 GLQVAMITGDNARTAAAIAKQVGIE--KVLAEVLPQDKVAEVRRLQDQGR Rv0969|M.tuberculosis_H37Rv GLQVAMITGDNARTAAAIAKQVGIE--KVLAEVLPQDKVAEVRRLQDQGR MMAR_2536|M.marinum_M GLQVAMITGDNARTAAAIAGQVGID--RVLAEVLPEDKVNEVRRLQDEGR MUL_0423|M.ulcerans_Agy99 GLQVALITGDNARTAAAIAAQVGID--RVLAEVLPADKVNEVRRLQDEGR Mflv_2244|M.gilvum_PYR-GCK GLTPIMVTGDNEAVARTVAAQVGID--EVVAGVLPQDKVDTVTRLQRDGR Mvan_4449|M.vanbaalenii_PYR-1 GLTPIMVTGDNEAVARAVAAEVGID--EVIAGVLPQDKVDTVKRLQRDGK MSMEG_5014|M.smegmatis_MC2_155 GLQPIMLTGDNGAAARAIADQVGID--DVYAEVLPQDKADVIKRLQAEGR MAV_5246|M.avium_104 GLTPILLTGDNHTVARRTAGELGIG--EVISGALPADKVEAVKRLQSAGR TH_4361|M.thermoresistible__bu GATPVLLTGDNDRAARTVAAQVGID--DVIAGVLPAEKVDHIKQLQDRGR MAB_3984c|M.abscessus_ATCC_199 GITPVLLTGDNAEVAARVASEVGIAAGDVIAGVKPTEKADVVKRLQAEGK MLBr_01987|M.leprae_Br4923 GFRTALLTGDNPASAAAVASRIGID--EVIADILPEDKVDVIEQLRDRGH * ::**** * * .:** * : * :*. : :*: *: Mb0994|M.bovis_AF2122/97 VVAMVGDGVNDAPALVQADLGIAIGTGTDVAIEASDITLMSGRLDGVVRA Rv0969|M.tuberculosis_H37Rv VVAMVGDGVNDAPALVQADLGIAIGTGTDVAIEASDITLMSGRLDGVVRA MMAR_2536|M.marinum_M LVAMVGDGVNDAPALVQADLGIAIGTGTDVAIEASDITLMSGRLDGVVRS MUL_0423|M.ulcerans_Agy99 IVAMVGDGVNDAPALVQADLGIAIGTGTDVAIEASDITLMSGRLDGVVSA Mflv_2244|M.gilvum_PYR-GCK VVAMVGDGVNDAAALAQADLGMAMGSGTDVAIEASDLTLVSNDLRAVPDA Mvan_4449|M.vanbaalenii_PYR-1 VVAMVGDGVNDAAALAQADLGLAMGSGTDVAIEASDLTLVSNDLRAVPDA MSMEG_5014|M.smegmatis_MC2_155 VVAMVGDGVNDAAALAQADLGLSMGTGTDVAIEAGDLTLVRGDLRTAADA MAV_5246|M.avium_104 VVAMVGDGVNDAAALAAADLGLAMGTGTDVAIEAADVTVVRGDLRAAVDA TH_4361|M.thermoresistible__bu VVAMIGDGVNDAAALAQADLGLAIGTGTDVAIEASDLTLVTGDLRAAPDA MAB_3984c|M.abscessus_ATCC_199 RVAMVGDGVNDSAALATADIGMAMGTGTDAAIEASDLTLVRGDLTTVPTA MLBr_01987|M.leprae_Br4923 VVAMVGDGINDGPALARADLGMAIGRGTDVAIGAADIILVRDNLDVVPIT ***:***:**..**. **:*:::* ***.** *.*: :: . * . : Mb0994|M.bovis_AF2122/97 IELSRQTLRTIYQNLGWAFGYNTAAIPLAALGALNPVVAGAAMGFSSVSV Rv0969|M.tuberculosis_H37Rv IELSRQTLRTIYQNLGWAFGYNTAAIPLAALGALNPVVAGAAMGFSSVSV MMAR_2536|M.marinum_M LQLSRQTLRTIHQNLGWAFGYNTAAIPLAAFGLLNPVVAGAAMGLSSVSV MUL_0423|M.ulcerans_Agy99 IELSRRTLRTIYQNLGWAFGYNTAAIPLAALGVLNPVVAGAAMGLSSVSV Mflv_2244|M.gilvum_PYR-GCK IRLSRKTLSTIKSNLFWAFAYNVAALPLAAAGLLNPMIAGAAMAFSSVFV Mvan_4449|M.vanbaalenii_PYR-1 IRLSRKTLSTIKGNLFWAFAYNVAALPLAAAGLLNPMIAGAAMAFSSVFV MSMEG_5014|M.smegmatis_MC2_155 IRLSRRTLATIKGNLFWAFAYNVAALPLAAAGLLNPMLAGAAMAFSSVFV MAV_5246|M.avium_104 IRLSRRTLATIKTNLVWAFGYNLAAIPLAALGMLNPMLAGAAMALSSVLV TH_4361|M.thermoresistible__bu IRLGRATLRTIKGNLFWAFAYNVAALPLAAAGLLNPLIAGAAMAFSSVFV MAB_3984c|M.abscessus_ATCC_199 LRLSRKTLGTIKANLFWAFAYNTAAIPLAALGLLNPMIAGAAMAMSSVFV MLBr_01987|M.leprae_Br4923 LDLAAATMRTIKFNMVWAFGYNIAAIPIAAAGLLNPLVAGAAMAFSSFFV : *. *: ** *: ***.** **:*:** * ***::*****.:**. * Mb0994|M.bovis_AF2122/97 VTNSLRLRRFGRDGRTA--------------------------------- Rv0969|M.tuberculosis_H37Rv VTNSLRLRRFGRDGRTA--------------------------------- MMAR_2536|M.marinum_M VTNSLRLRRFGRDT------------------------------------ MUL_0423|M.ulcerans_Agy99 VTNSLRLRRFGRDV------------------------------------ Mflv_2244|M.gilvum_PYR-GCK VTNSLRLRAFTPSR------------------------------------ Mvan_4449|M.vanbaalenii_PYR-1 VSNSLRLRAFTPSR------------------------------------ MSMEG_5014|M.smegmatis_MC2_155 VSNSLRLKRFR--------------------------------------- MAV_5246|M.avium_104 VGNSLRLRSFASIIPGA--------------------------------- TH_4361|M.thermoresistible__bu VSNSLRLRRFTPSR------------------------------------ MAB_3984c|M.abscessus_ATCC_199 VLNSLRLRTFR--------------------------------------- MLBr_01987|M.leprae_Br4923 VSNSLRLRNFGAILSCGTSRHRTVKRWRCPPPTRLRSTACSPVDASPLRP * *****: * Mb0994|M.bovis_AF2122/97 ------------- Rv0969|M.tuberculosis_H37Rv ------------- MMAR_2536|M.marinum_M ------------- MUL_0423|M.ulcerans_Agy99 ------------- Mflv_2244|M.gilvum_PYR-GCK ------------- Mvan_4449|M.vanbaalenii_PYR-1 ------------- MSMEG_5014|M.smegmatis_MC2_155 ------------- MAV_5246|M.avium_104 ------------- TH_4361|M.thermoresistible__bu ------------- MAB_3984c|M.abscessus_ATCC_199 ------------- MLBr_01987|M.leprae_Br4923 VAHRTGVKPPTHR