For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. marinum M MMAR_2536 (-)

annotation: metal cation transporter p-type ATPase
coordinates: 3089369 - 3091663
length: 764

RVRISGHHIDAVRAVAIEDVVAEVAGVHAVQAYPRSASVVIWYAPEDCDTAAVLSAISDAQYIPAELVPA
RAPHSSNPSNTGVVQKITGGILRLLGLSPDTDTRDTAGEGSCHQPAASCHGAPAADAKGEQRKWLRRVWL
AAPLGLVSMAAPMLFGASWAGWLAFAATVPVQFVAGWPFLKGAVQQARAGSAGMDTLIALGTLTAFAYST
YGLFAGGPLFFDTAALIIAFVVLGRYFEARATGKTREAISTLLEMGAKEACLLIDGQEVLVPVEQVQVGD
LLLVRPGEKIPVDGEITDGRAAVDESMLTGESVPVEKTVGDRVAGATVNTDGLLTVRATAVGADTALAQI
VRLVEQAQGGKAPVQRLADRVSAVFVPAVLGVAALTFAGWALIAANPIAGMTAAVSVLIIACPCALGLAT
PTAIIVGTGRGAEMGILVKGGEVLEASKKIDTVVFDKTGTLTRGKMQLTDVIPDKRQKSDLVLGLAAAVE
SGSEHPVGAAIVAGARERELEIPAATSFTNLAGHGVRAEVDGQVVLVGRRKLVDENDLRLSDHLAAVAAE
LEEQGRTAVFVGRGDRVVGVLAVADTIKDDAVEVVRQLHEMGLQVAMITGDNARTAAAIAGQVGIDRVLA
EVLPEDKVNEVRRLQDEGRLVAMVGDGVNDAPALVQADLGIAIGTGTDVAIEASDITLMSGRLDGVVRSL
QLSRQTLRTIHQNLGWAFGYNTAAIPLAAFGLLNPVVAGAAMGLSSVSVVTNSLRLRRFGRDT*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_2536--100% (764)metal cation transporter p-type ATPase
M. marinum MMMAR_1431zntA0.081.14% (774) cation transport ATPase, ZntA
M. marinum MMMAR_4876ctpV0.076.68% (776) metal cation transporter p-type ATPase, CtpV

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0994ctpV0.078.46% (766) metal cation transporter P-type ATPase CtpV
M. gilvum PYR-GCKMflv_2244-1e-17751.37% (658) heavy metal translocating P-type ATPase
M. tuberculosis H37RvRv0969ctpV0.078.59% (766) metal cation transporter P-type ATPase CtpV
M. leprae Br4923MLBr_01987ctpA1e-14846.56% (640) putative cation-transporting ATPase
M. abscessus ATCC 19977MAB_3984c-1e-16048.73% (669) putative metal transporter ATPase
M. avium 104MAV_5246-1e-16547.90% (691) copper-translocating P-type ATPase
M. smegmatis MC2 155MSMEG_5014-1e-17950.51% (693) copper-translocating P-type ATPase
M. thermoresistible (build 8)TH_4361-0.051.98% (681) PUTATIVE heavy metal translocating P-type ATPase
M. ulcerans Agy99MUL_0423ctpV0.075.90% (776) metal cation transporter p-type ATPase, CtpV
M. vanbaalenii PYR-1Mvan_4449-1e-17852.15% (650) heavy metal translocating P-type ATPase

CLUSTAL 2.0.9 multiple sequence alignment


Mb0994|M.bovis_AF2122/97            --MRVCVTGFNVDAVRAVAIEETVSQVTGVHAVHAYPRTASVVIWYSPEL
Rv0969|M.tuberculosis_H37Rv         --MRVCVTGFNVDAVRAVAIEETVSQVTGVHAVHAYPRTASVVIWYSPEL
MMAR_2536|M.marinum_M               --MRVRISGHHIDAVRAVAIEDVVAEVAGVHAVQAYPRSASVVIWYAPED
MUL_0423|M.ulcerans_Agy99           --MRVHANGFAIDATRAAAIEESVGRVGGVRAVRAYPRTASVVIWYSPAH
Mflv_2244|M.gilvum_PYR-GCK          -------------------MNTLELSIGGMTCASCAAR---VEKKLNKLD
Mvan_4449|M.vanbaalenii_PYR-1       -------------------MNTIELSIGGMTCASCAAR---VEKKLNKLD
MSMEG_5014|M.smegmatis_MC2_155      ---------------MTTATGHVELQIGGMTCASCAAR---IERKLNKLD
MAV_5246|M.avium_104                MSTPPRHIDEGTFPDHTASTARIELEITGMTCASCAAR---IEKKLNKLD
TH_4361|M.thermoresistible__bu      --------------MNTGGMNTVTLTVGGMTCASCAAR---VEKRLNRID
MAB_3984c|M.abscessus_ATCC_199      ------------METTNTGMETTDLRLHGMTCASCASR---VEKGLNKIT
MLBr_01987|M.leprae_Br4923          -----------------------------MRAPNGWNN------LPNKLS
                                                                 : .     .            

Mb0994|M.bovis_AF2122/97            GDTAAVLSAITKAQHVPAELVPARAPHSAGVRGVGVVRKITGGIRRMLS-
Rv0969|M.tuberculosis_H37Rv         GDTAAVLSAITKAQHVPAELVPARAPHSAGVRGVGVVRKITGGIRRMLS-
MMAR_2536|M.marinum_M               CDTAAVLSAISDAQYIPAELVPARAPHSSNPSNTGVVQKITGGILRLLG-
MUL_0423|M.ulcerans_Agy99           CDTAAIVSAIAEAEHAGDASAPAPAARVAGIADGGVVGRVIGGLARALLG
Mflv_2244|M.gilvum_PYR-GCK          GVTATVNYATEKARVEFGDNVST-DQLVSAVESAGYQAALPEP-------
Mvan_4449|M.vanbaalenii_PYR-1       GVTATVNFATEKARVAFGDEVSP-GQLVSAVESAGYQAELPER-------
MSMEG_5014|M.smegmatis_MC2_155      GVTASVNYATEKASVEVAGEVSP-ETLIEVVETAGYTAHLPAP-------
MAV_5246|M.avium_104                GVTATVNYATEKAAVSAPASYDP-QTLITEIENAGYAAAVATP-------
TH_4361|M.thermoresistible__bu      GVVATVNFATEQATVRYPDHVDP-ADLIAAIEATGYTASLPAPQRDTGGA
MAB_3984c|M.abscessus_ATCC_199      GVNARVNLALESARVEHDGSVTG-EDLVKAVESVGYTAQVVGGSHQDAHA
MLBr_01987|M.leprae_Br4923          DFSTLVNSATRVAAINLSEVTQT-AEVCEAVRRAALCTDGGEALQR----
                                       : :  *   *                     .               

Mb0994|M.bovis_AF2122/97            ---------RPPGVDKPLKASRCGGRPRGPVRGSASWPGEQNRRERRTWL
Rv0969|M.tuberculosis_H37Rv         ---------RPPGVDKPLKASRCGGRPRGPVRGSASWPGEQNRRERRTWL
MMAR_2536|M.marinum_M               ---------LSPDTDT--RDTAGEGSCHQPAASCHGAPAADAKGEQRKWL
MUL_0423|M.ulcerans_Agy99           MRTDDNDDDPPPEIARLRAALDRIGYSPEQDTATQLSPSEQARSGIRFWS
Mflv_2244|M.gilvum_PYR-GCK          -------------------------PNPPD-----VEPADPTAALRRRLI
Mvan_4449|M.vanbaalenii_PYR-1       -------------------------PDEPA-----EPTDDPTAALKRRLL
MSMEG_5014|M.smegmatis_MC2_155      -------------------------PQPETGGTEQDPEDRATDALRTRLL
MAV_5246|M.avium_104                -------------------------SPPRD--------DPELASLRRRLV
TH_4361|M.thermoresistible__bu      -------------------------PAGAATGAAGDDHDAEAERWRRRLT
MAB_3984c|M.abscessus_ATCC_199      G------------------------DHDGHDPHDHMNHDVPDDQLKSRLI
MLBr_01987|M.leprae_Br4923          ----------------------------------RQADADNARYLLIRLA
                                                                                      

Mb0994|M.bovis_AF2122/97            PRVWLALPLGLLA-LGSSMFFGAYPWAGWLAFAATLPVQFVAGWPILRGA
Rv0969|M.tuberculosis_H37Rv         PRVWLALPLGLLA-LGSSMFFGAYPWAGWLAFAATLPVQFVAGWPILRGA
MMAR_2536|M.marinum_M               RRVWLAAPLGLVS-MAAPMLFGAS-WAGWLAFAATVPVQFVAGWPFLKGA
MUL_0423|M.ulcerans_Agy99           RRAWLAWPLGLLA-SGLTMFFGAYPWAGWLAFAATIPVQFIAGWPFLVGA
Mflv_2244|M.gilvum_PYR-GCK          ICVALSVPVIAMA-MAPPLQFTYW---QWLSLTLAAPVVVWGAWPFHRAT
Mvan_4449|M.vanbaalenii_PYR-1       ICVALSVPVIAMA-MVPVLQFTYW---QWLSLTLAAPVVVWGAWPFHQAA
MSMEG_5014|M.smegmatis_MC2_155      VSAVLTVPVIAMA-MVPALQFTNW---QWLSLTLAAPVVVWGALPFHRAA
MAV_5246|M.avium_104                TAIALAGPVIAVA-MIPALQFQHW---HWAALALTAPVVGWCGRPFHAAA
TH_4361|M.thermoresistible__bu      ISAALSIPVVVLS-MIPALQFTHW---QWLALTLTSPVVVWGAWPFHRAA
MAB_3984c|M.abscessus_ATCC_199      GSLILAIPVVVIS-MAMPLHFSGW---EILVAALTTPILLWGGYPFHRAA
MLBr_01987|M.leprae_Br4923          VAAALFVPLAHLSVMFAVLPSTHFPGWEWMLTALAIPVVTWAAWPFHRVA
                                        *  *:  ::     :             : : *:    . *:   :

Mb0994|M.bovis_AF2122/97            VQQARALTSNMDTLIALGTLTAFVYSTYQLFAG-----------------
Rv0969|M.tuberculosis_H37Rv         VQQARALTSNMDTLIALGTLTAFVYSTYQLFAG-----------------
MMAR_2536|M.marinum_M               VQQARAGSAGMDTLIALGTLTAFAYSTYGLFAG-----------------
MUL_0423|M.ulcerans_Agy99           VQQARARSANMNTLISLGTLTAFIYSTYQLFAG-----------------
Mflv_2244|M.gilvum_PYR-GCK          WANLRHGTATMDTLISVGTLAAFGWSIYALFWGTAGVPGMTHPFELTIAR
Mvan_4449|M.vanbaalenii_PYR-1       WTNLRHGTATMDTLISIGTLAALGWSIYALFWGTAGIPGMTHPFELTIAR
MSMEG_5014|M.smegmatis_MC2_155      WLNLRHGTATMDTLISMGTLAAFGWSLYALFWGTAGVPGMTHPFSLVGSR
MAV_5246|M.avium_104                WANLKHGVTTMDTLISIGTLAAFLWSLYALVLGAADRPGMRHDFELTVGH
TH_4361|M.thermoresistible__bu      VANLRHGTATMDTLISLGVTAAYLWSLWALFFTAAGMPGMTMTFTLLPAD
MAB_3984c|M.abscessus_ATCC_199      LVNARHGASTMDTLVSLGTIAAYLWSLWVLFANAGHT-------------
MLBr_01987|M.leprae_Br4923          IHNARYHGASMETLISTGITAATIWSLYTVFGHHQSTEHRGVWRALLG--
                                      : :   : *:**:: *  :*  :* : :.                   

Mb0994|M.bovis_AF2122/97            ----------GPLFFDTSALIIAFVVLGRHLEARATGKASEAISKLLELG
Rv0969|M.tuberculosis_H37Rv         ----------GPLFFDTSALIIAFVVLGRHLEARATGKASEAISKLLELG
MMAR_2536|M.marinum_M               ----------GPLFFDTAALIIAFVVLGRYFEARATGKTREAISTLLEMG
MUL_0423|M.ulcerans_Agy99           ----------GPLFFDTAALIIAFVVLGRYFEATAHGKTREAISKLLDMG
Mflv_2244|M.gilvum_PYR-GCK          ------TDGSGNIYLEAAAGVTTFILAGRYFEARAKRRAGAALRALLELG
Mvan_4449|M.vanbaalenii_PYR-1       ------TDGTSNIYLEAAAGVTTFILAGRYFEARAKRRAGAALRALLELG
MSMEG_5014|M.smegmatis_MC2_155      ------TDGAGNIYLEVAAGVTTFILAGRYFEAKSKRRASAALRALMELG
MAV_5246|M.avium_104                GAHVSHVAAPCHVYFEVAAGVTLFVLAGRYFERRSKRTAGAALRALLALG
TH_4361|M.thermoresistible__bu      -------TGEPHIYLEVAAAVTTFIIAGRYFEARAKRQSGAALRALLDMG
MAB_3984c|M.abscessus_ATCC_199      -------HGDVHVYFEVVAAVTVFLLAGRFAESRAKRSAGSALRALLSLG
MLBr_01987|M.leprae_Br4923          ---------SDAIYFEVAAGITVFVLAGKYYTARAKSHASIALLALAALS
                                                ::::. * :  *:: *:.    :   :  *:  *  :.

Mb0994|M.bovis_AF2122/97            AKEATLLV-DGQELLVPVDQVQVGDLVRVRPGEKIPVDGEVTDGRAAVDE
Rv0969|M.tuberculosis_H37Rv         AKEATLLV-DGQELLVPVDQVQVGDLVRVRPGEKIPVDGEVTDGRAAVDE
MMAR_2536|M.marinum_M               AKEACLLI-DGQEVLVPVEQVQVGDLLLVRPGEKIPVDGEITDGRAAVDE
MUL_0423|M.ulcerans_Agy99           AKETRLIV-DGEEHLVPVDRVQVGDLVRVRPGEKIPVDGEVIDGRAAVDE
Mflv_2244|M.gilvum_PYR-GCK          VRDVTVRR-GAAEHRIPIDQLRVDDEFVVRPGEKVAADGIIVEGASAVDA
Mvan_4449|M.vanbaalenii_PYR-1       AREVTVRR-GGAEQRIPIEQLVIGDEFVVRPGEKIAADGTVVEGASAVDA
MSMEG_5014|M.smegmatis_MC2_155      AKDVAILR-NGAEQRIPIDQLGVGDEFVVRPGEKIATDGVVVDGSSAVDA
MAV_5246|M.avium_104                AKDVAVLR-AGAETRIPIERLAVGDEFVVRPGERIATDGIVVAGSSAVDA
TH_4361|M.thermoresistible__bu      ANDVAVLR-DGAEKRVPIGELHVGDVFVVRPGEKIATDGEVVAGNSAVDA
MAB_3984c|M.abscessus_ATCC_199      AKDVAVLR-GGHETRIPVDQLAVGDEFVVRPGERVATDGEVIEGHSALDT
MLBr_01987|M.leprae_Br4923          AKDAAVLQPDGSEMVIPANELNEQQRFVVRPGQTIAADGLVIDGSATVSM
                                    ..:. :    . *  :*  .:   : . ****: :..** :  * :::. 

Mb0994|M.bovis_AF2122/97            SMLTGESVPVEKTAGDRVAGATVNLDGLLTVRATAVGADTALAQIVRLVE
Rv0969|M.tuberculosis_H37Rv         SMLTGESVPVEKTAGDRVAGATVNLDGLLTVRATAVGADTALAQIVRLVE
MMAR_2536|M.marinum_M               SMLTGESVPVEKTVGDRVAGATVNTDGLLTVRATAVGADTALAQIVRLVE
MUL_0423|M.ulcerans_Agy99           SMLTGESVPVEKGVGDWVAGATVNTDGLLTVRATAVGADTALAQIVRLVE
Mflv_2244|M.gilvum_PYR-GCK          SMLTGESVPLEVKPGDRVVGATVNVDGRLVVRAERVGADTQLAQMARLVE
Mvan_4449|M.vanbaalenii_PYR-1       SMLTGESVPEEVQPGDQVVGATVNVDGRLVVRADRVGSDTQLAQMARMVE
MSMEG_5014|M.smegmatis_MC2_155      SMLTGESVPVEVGPGDQVVGATVNVGGRLVVRANRIGSDTQLAQMARLVE
MAV_5246|M.avium_104                AMLTGESVPVEVGVGDGVTGGTVNAGGRLVVRATGIGDDTQLARMAQLVE
TH_4361|M.thermoresistible__bu      SMLTGESVPVEVGPGDQVVGATVNVGGHLQVRATRVGADTQLAQMARLVT
MAB_3984c|M.abscessus_ATCC_199      STMTGESVPMEVTVGGPVLGGYVNTHGRIVVRANKVGADTQLARMARLVS
MLBr_01987|M.leprae_Br4923          SPITGEAKPVRVNPGAQVIGGTVVLNGRLIVEAAAVGDETQLAGMVRLVE
                                    : :***: * .   *  * *. *   * : *.*  :* :* ** :.::* 

Mb0994|M.bovis_AF2122/97            QAQGDKAPVQRLADRVSAVFVPAVIGVAVATFAGWTLIAANPVAG-MTAA
Rv0969|M.tuberculosis_H37Rv         QAQGDKAPVQRLADRVSAVFVPAVIGVAVATFAGWTLIAANPVAG-MTAA
MMAR_2536|M.marinum_M               QAQGGKAPVQRLADRVSAVFVPAVLGVAALTFAGWALIAANPIAG-MTAA
MUL_0423|M.ulcerans_Agy99           EAQGGKAPVQRLADRVSAVFVPVVVRIAAATFAGWTLLAANPVAG-MTAA
Mflv_2244|M.gilvum_PYR-GCK          DAQNGKAQAQRLADRISGVFVPVVLGLAVATLGFWIG-SGYPVAAAFTAA
Mvan_4449|M.vanbaalenii_PYR-1       DAQNGKAQAQRLADRISGVFVPIVIALSVATLGFWIG-SGFPVAAAFTAA
MSMEG_5014|M.smegmatis_MC2_155      DAQSGKAQAQRLADRVSAVFVPIVIALAVATLGFWLG-TGGSVAAAFTAA
MAV_5246|M.avium_104                RAQSGKADAQRLADRVSGVFVPVVLLLAVATLAGWLA-AGGTLATALTAA
TH_4361|M.thermoresistible__bu      EAQSGKAEVQRLADRVSAVFVPIVIALSALTLAGWLLLTDAPVSAAFTAA
MAB_3984c|M.abscessus_ATCC_199      DAQTGKAQVQRLADRVSSVFVPVVLAISALTFVAWAA-LGNSLASAFTAA
MLBr_01987|M.leprae_Br4923          QAQQQNANAQRLADRIASVFVPCVFAVAALTAVGWLI-AGSGPDRVFSAA
                                     **  :* .******::.**** *. ::. *   *           ::**

Mb0994|M.bovis_AF2122/97            VAVLIIACPCALGLATPTAIMVGTGRGAELGILVKGGEVLEASKKIDTVV
Rv0969|M.tuberculosis_H37Rv         VAVLIIACPCALGLATPTAIMVGTGRGAELGILVKGGEVLEASKKIDTVV
MMAR_2536|M.marinum_M               VSVLIIACPCALGLATPTAIIVGTGRGAEMGILVKGGEVLEASKKIDTVV
MUL_0423|M.ulcerans_Agy99           VSVLIIACPYALGLATPTAIIVGTGRGADMGILVKGGEVLEASKKIDTVV
Mflv_2244|M.gilvum_PYR-GCK          VAVLIIACPCALGLATPMALMVGTGRGAQLGILIKGPEVLESTRRVDTVI
Mvan_4449|M.vanbaalenii_PYR-1       VAVLIIACPCALGLATPTALMVGTGRGAQLGILIKGPEVLEDTRRVDTVI
MSMEG_5014|M.smegmatis_MC2_155      VAVLIIACPCALGLATPTALLVGTGRGAQLGILIKGPEVLESTRRVDTIV
MAV_5246|M.avium_104                VAVLIIACPCALGLATPTALLVGTGRAAQLGVLIKGPEVLETTRAVDTVV
TH_4361|M.thermoresistible__bu      VAVLIIACPCALGLATPTALLVGTGRGAQLGILIKGPQVLESTRRIDTVV
MAB_3984c|M.abscessus_ATCC_199      VAVLIIACPCALGLATPTAILVGTGRGAQLGVLIKGPEVLENVKDIDTVV
MLBr_01987|M.leprae_Br4923          IAVLVIACPCALGLATPTAMMVASGRGAQLGILLKGHESFEATRAVDTVV
                                    ::**:**** ******* *::*.:**.*::*:*:** : :*  : :**::

Mb0994|M.bovis_AF2122/97            FDKTGTLTRARMRVTDVIAGQRR---QPNQVLRLAAAVESGSEHPIGAAI
Rv0969|M.tuberculosis_H37Rv         FDKTGTLTRARMRVTDVIAGQRR---QPDQVLRLAAAVESGSEHPIGAAI
MMAR_2536|M.marinum_M               FDKTGTLTRGKMQLTDVIPDKRQ---KSDLVLGLAAAVESGSEHPVGAAI
MUL_0423|M.ulcerans_Agy99           FDKTGTLTRAQMELTDVIAGKRR---QPDVVLRIAAAVESGSEHPIGAAI
Mflv_2244|M.gilvum_PYR-GCK          VDKTGTVTTGDMTLVDVFAADGE---QPDEVLRMAGAVESPSEHPIAAAI
Mvan_4449|M.vanbaalenii_PYR-1       LDKTGTVTTGSMTLVDVFAAEGE---QPDEVLRVAGAVESSSEHPIARAI
MSMEG_5014|M.smegmatis_MC2_155      LDKTGTITTGSMTLLDVVVADGE---DRDDVLRVAAAVEDASEHPIARAI
MAV_5246|M.avium_104                LDKTGTVTTGAMTVLDVVAADGT---DRATLLRYAGALEAASEHPIAHAI
TH_4361|M.thermoresistible__bu      LDKTGTVTTGQMSVTSVHVADGL---SETELLRLAGAVEHASEHPIARAV
MAB_3984c|M.abscessus_ATCC_199      LDKTGTVTTGVMSVVEVRRSIGSGVADADEILRIAASVESASEHPVARAI
MLBr_01987|M.leprae_Br4923          FDKTGTLTTGQLKVSAVTAAPGW---QANEVLQMAATVESASEHAVALAI
                                    .*****:* . : :  *         .   :*  *.::*  ***.:. *:

Mb0994|M.bovis_AF2122/97            VAAAHERGLAIPAANAFTAVAGHGVRAQVNGGPVVVGRRKLVDEQHLVLP
Rv0969|M.tuberculosis_H37Rv         VAAAHERGLAIPAANAFTAVAGHGVRAQVNGGPVVVGRRKLVDEQHLVLP
MMAR_2536|M.marinum_M               VAGARERELEIPAATSFTNLAGHGVRAEVDGQVVLVGRRKLVDENDLRLS
MUL_0423|M.ulcerans_Agy99           VAGARERELEVPPATEFTNLAGHGVRGEVGGKSVLVGRRKLVDEQHLRLP
Mflv_2244|M.gilvum_PYR-GCK          AGGARDKLGDLPAVDGFANLRGLGVEGDVEGRRLTLGRLRLLSDRSFEIP
Mvan_4449|M.vanbaalenii_PYR-1       AAGAQEKFGELPAVTAFTNLRGLGVSGQVDGRAVLLGRLRLLADRSHEIP
MSMEG_5014|M.smegmatis_MC2_155      AAGARERTGELPAVEGFANIEGLGVQGTVEGRAVVVGRPRLFGDPEKSLP
MAV_5246|M.avium_104                ARDAKAELGPLPTPTGFRAVGGGGVHGRVDGHAVAIGRPSWLAERGLRPD
TH_4361|M.thermoresistible__bu      ATHAAQTVPPLPEVSDFENHGGNGVSGRVDGHDVRVGRLAWLG---LSAG
MAB_3984c|M.abscessus_ATCC_199      VAAAASARLTLSPVTNFRNEPGVGVSGVVDGQEVSI--------------
MLBr_01987|M.leprae_Br4923          AASTTHR----EPVANFRAVPGHGVSGTVAERAVRVGKPSWIASR--CNS
                                    .  :            *    * ** . *    : :              

Mb0994|M.bovis_AF2122/97            DHLAAAAVEQEERGRTAVFVGQDGQVVGVLAVADTVKDDAADVVGRLHAM
Rv0969|M.tuberculosis_H37Rv         DHLAAAAVEQEERGRTAVFVGQDGQVVGVLAVADTVKDDAADVVGRLHAM
MMAR_2536|M.marinum_M               DHLAAVAAELEEQGRTAVFVGRGDRVVGVLAVADTIKDDAVEVVRQLHEM
MUL_0423|M.ulcerans_Agy99           EQLAAAAADLEERGRTAVYVGQDGQVVGVLAVADTVKDDAADVVSQLHAM
Mflv_2244|M.gilvum_PYR-GCK          DDLASAVARAEAGGSTAVTVGWDGRARGVLMVADAVKPTSAEAISLLKRA
Mvan_4449|M.vanbaalenii_PYR-1       SELEVAVARAESDGRTAVVVGWDGQARGVLMVADAVKPTSAEAISLLKRL
MSMEG_5014|M.smegmatis_MC2_155      RKLADAMEAAQAQGRTAVVVGWDGTARGVLVVADAVKATSAEAIGQLRKL
MAV_5246|M.avium_104                AALAAAAARAEHDGKTVVAVGWDGRARGILALADTVKPSSAAAVRQFTRL
TH_4361|M.thermoresistible__bu      DRLRNAAAQAEAAGHTPVWVAVDGRIAGVIVVSDTVKDHAAEAIAELRAL
MAB_3984c|M.abscessus_ATCC_199      --------EAIEGQNTTAAVSWGGLRRGEIEVADTVKPSSRRAIDELKAM
MLBr_01987|M.leprae_Br4923          TTLVTARRNAELRGETAVFVEIDGEQCGVIAVADAVKASAADAVAALHDR
                                                   * . *  ..   * : ::*::*  :  .:  :   

Mb0994|M.bovis_AF2122/97            GLQVAMITGDNARTAAAIAKQVGIE--KVLAEVLPQDKVAEVRRLQDQGR
Rv0969|M.tuberculosis_H37Rv         GLQVAMITGDNARTAAAIAKQVGIE--KVLAEVLPQDKVAEVRRLQDQGR
MMAR_2536|M.marinum_M               GLQVAMITGDNARTAAAIAGQVGID--RVLAEVLPEDKVNEVRRLQDEGR
MUL_0423|M.ulcerans_Agy99           GLQVALITGDNARTAAAIAAQVGID--RVLAEVLPADKVNEVRRLQDEGR
Mflv_2244|M.gilvum_PYR-GCK          GLTPIMVTGDNEAVARTVAAQVGID--EVVAGVLPQDKVDTVTRLQRDGR
Mvan_4449|M.vanbaalenii_PYR-1       GLTPIMVTGDNEAVARAVAAEVGID--EVIAGVLPQDKVDTVKRLQRDGK
MSMEG_5014|M.smegmatis_MC2_155      GLQPIMLTGDNGAAARAIADQVGID--DVYAEVLPQDKADVIKRLQAEGR
MAV_5246|M.avium_104                GLTPILLTGDNHTVARRTAGELGIG--EVISGALPADKVEAVKRLQSAGR
TH_4361|M.thermoresistible__bu      GATPVLLTGDNDRAARTVAAQVGID--DVIAGVLPAEKVDHIKQLQDRGR
MAB_3984c|M.abscessus_ATCC_199      GITPVLLTGDNAEVAARVASEVGIAAGDVIAGVKPTEKADVVKRLQAEGK
MLBr_01987|M.leprae_Br4923          GFRTALLTGDNPASAAAVASRIGID--EVIADILPEDKVDVIEQLRDRGH
                                    *    ::****   *   * .:**    * :   * :*.  : :*:  *:

Mb0994|M.bovis_AF2122/97            VVAMVGDGVNDAPALVQADLGIAIGTGTDVAIEASDITLMSGRLDGVVRA
Rv0969|M.tuberculosis_H37Rv         VVAMVGDGVNDAPALVQADLGIAIGTGTDVAIEASDITLMSGRLDGVVRA
MMAR_2536|M.marinum_M               LVAMVGDGVNDAPALVQADLGIAIGTGTDVAIEASDITLMSGRLDGVVRS
MUL_0423|M.ulcerans_Agy99           IVAMVGDGVNDAPALVQADLGIAIGTGTDVAIEASDITLMSGRLDGVVSA
Mflv_2244|M.gilvum_PYR-GCK          VVAMVGDGVNDAAALAQADLGMAMGSGTDVAIEASDLTLVSNDLRAVPDA
Mvan_4449|M.vanbaalenii_PYR-1       VVAMVGDGVNDAAALAQADLGLAMGSGTDVAIEASDLTLVSNDLRAVPDA
MSMEG_5014|M.smegmatis_MC2_155      VVAMVGDGVNDAAALAQADLGLSMGTGTDVAIEAGDLTLVRGDLRTAADA
MAV_5246|M.avium_104                VVAMVGDGVNDAAALAAADLGLAMGTGTDVAIEAADVTVVRGDLRAAVDA
TH_4361|M.thermoresistible__bu      VVAMIGDGVNDAAALAQADLGLAIGTGTDVAIEASDLTLVTGDLRAAPDA
MAB_3984c|M.abscessus_ATCC_199      RVAMVGDGVNDSAALATADIGMAMGTGTDAAIEASDLTLVRGDLTTVPTA
MLBr_01987|M.leprae_Br4923          VVAMVGDGINDGPALARADLGMAIGRGTDVAIGAADIILVRDNLDVVPIT
                                     ***:***:**..**. **:*:::* ***.** *.*: :: . *  .  :

Mb0994|M.bovis_AF2122/97            IELSRQTLRTIYQNLGWAFGYNTAAIPLAALGALNPVVAGAAMGFSSVSV
Rv0969|M.tuberculosis_H37Rv         IELSRQTLRTIYQNLGWAFGYNTAAIPLAALGALNPVVAGAAMGFSSVSV
MMAR_2536|M.marinum_M               LQLSRQTLRTIHQNLGWAFGYNTAAIPLAAFGLLNPVVAGAAMGLSSVSV
MUL_0423|M.ulcerans_Agy99           IELSRRTLRTIYQNLGWAFGYNTAAIPLAALGVLNPVVAGAAMGLSSVSV
Mflv_2244|M.gilvum_PYR-GCK          IRLSRKTLSTIKSNLFWAFAYNVAALPLAAAGLLNPMIAGAAMAFSSVFV
Mvan_4449|M.vanbaalenii_PYR-1       IRLSRKTLSTIKGNLFWAFAYNVAALPLAAAGLLNPMIAGAAMAFSSVFV
MSMEG_5014|M.smegmatis_MC2_155      IRLSRRTLATIKGNLFWAFAYNVAALPLAAAGLLNPMLAGAAMAFSSVFV
MAV_5246|M.avium_104                IRLSRRTLATIKTNLVWAFGYNLAAIPLAALGMLNPMLAGAAMALSSVLV
TH_4361|M.thermoresistible__bu      IRLGRATLRTIKGNLFWAFAYNVAALPLAAAGLLNPLIAGAAMAFSSVFV
MAB_3984c|M.abscessus_ATCC_199      LRLSRKTLGTIKANLFWAFAYNTAAIPLAALGLLNPMIAGAAMAMSSVFV
MLBr_01987|M.leprae_Br4923          LDLAAATMRTIKFNMVWAFGYNIAAIPIAAAGLLNPLVAGAAMAFSSFFV
                                    : *.  *: **  *: ***.** **:*:** * ***::*****.:**. *

Mb0994|M.bovis_AF2122/97            VTNSLRLRRFGRDGRTA---------------------------------
Rv0969|M.tuberculosis_H37Rv         VTNSLRLRRFGRDGRTA---------------------------------
MMAR_2536|M.marinum_M               VTNSLRLRRFGRDT------------------------------------
MUL_0423|M.ulcerans_Agy99           VTNSLRLRRFGRDV------------------------------------
Mflv_2244|M.gilvum_PYR-GCK          VTNSLRLRAFTPSR------------------------------------
Mvan_4449|M.vanbaalenii_PYR-1       VSNSLRLRAFTPSR------------------------------------
MSMEG_5014|M.smegmatis_MC2_155      VSNSLRLKRFR---------------------------------------
MAV_5246|M.avium_104                VGNSLRLRSFASIIPGA---------------------------------
TH_4361|M.thermoresistible__bu      VSNSLRLRRFTPSR------------------------------------
MAB_3984c|M.abscessus_ATCC_199      VLNSLRLRTFR---------------------------------------
MLBr_01987|M.leprae_Br4923          VSNSLRLRNFGAILSCGTSRHRTVKRWRCPPPTRLRSTACSPVDASPLRP
                                    * *****: *                                        

Mb0994|M.bovis_AF2122/97            -------------
Rv0969|M.tuberculosis_H37Rv         -------------
MMAR_2536|M.marinum_M               -------------
MUL_0423|M.ulcerans_Agy99           -------------
Mflv_2244|M.gilvum_PYR-GCK          -------------
Mvan_4449|M.vanbaalenii_PYR-1       -------------
MSMEG_5014|M.smegmatis_MC2_155      -------------
MAV_5246|M.avium_104                -------------
TH_4361|M.thermoresistible__bu      -------------
MAB_3984c|M.abscessus_ATCC_199      -------------
MLBr_01987|M.leprae_Br4923          VAHRTGVKPPTHR