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MTSPLSVGIIGAGPGGLALGILLKNRGFENFTIFDRESDVGGTWRINTYPGLACDVKSHLYSYSFDLNPG WSRLWSGQPEILAYFQRCADRYGLRPHLRLSTEIRSARWESQTRQWTLSTADGEQHQFSVVVSAVGIFSR PAYPDLVEQQRFTGTVMHSSRWDHSVPLAGARIAVLGTGSTAAQLVPELAKVADRVYSIQRSPTWILPKP DRPYSRWERWVFAHVPFAARLYRTRLWLRSESNISVIEHGSPKTKEFTELALRMLENTVSDPQLRRQLTP DHPMGCKRLVFSSEFLTALARPNVELVTSPARYLRQRSLVTADGAEYDVDVVVCATGYAAADYLGQLEVL GEDGAGLHEVWRDGAHAYLGMAVPGFPNFFMLYGPNTNVGSNSVIFMLEAQARYIVAALAHLRRKSKTYI AVRPGVLAEFMAKVDRWMTGTVWTTECSNYFRAPNGRVVTQWPRSARSFWGMTRRFKPADFSFQPAAVFA ADGGDRNAGQR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0403 | - | - | 100% (501) | monooxygenase |
| M. marinum M | MMAR_0240 | - | e-116 | 43.93% (494) | monoooxygenase |
| M. marinum M | MMAR_3136 | - | e-106 | 41.06% (492) | monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0916 | - | 6e-92 | 36.92% (493) | monooxygenase |
| M. gilvum PYR-GCK | Mflv_4103 | - | 0.0 | 71.28% (484) | cyclohexanone monooxygenase |
| M. tuberculosis H37Rv | Rv0892 | - | 6e-92 | 36.92% (493) | monooxygenase |
| M. leprae Br4923 | MLBr_00065 | - | 1e-28 | 25.44% (397) | putative monooxygenase |
| M. abscessus ATCC 19977 | MAB_2077 | - | 1e-100 | 40.55% (476) | monooxygenase |
| M. avium 104 | MAV_5119 | - | 0.0 | 78.19% (486) | lipolytic enzyme |
| M. smegmatis MC2 155 | MSMEG_2567 | - | 0.0 | 74.53% (479) | monooxygenase |
| M. thermoresistible (build 8) | TH_3452 | - | 0.0 | 74.07% (486) | PUTATIVE lipolytic enzyme |
| M. ulcerans Agy99 | MUL_1053 | - | 0.0 | 98.40% (501) | monooxygenase |
| M. vanbaalenii PYR-1 | Mvan_2243 | - | 0.0 | 71.22% (483) | cyclohexanone monooxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0916|M.bovis_AF2122/97 --------MTGRCPTVAVVGAGMSGMCVAITLLSAG-ITDVCIYEKADDV
Rv0892|M.tuberculosis_H37Rv --------MTGRCPTVAVVGAGMSGMCVAITLLSAG-ITDVCIYEKADDV
MMAR_0403|M.marinum_M ---------MTSPLSVGIIGAGPGGLALGILLKNRG-FENFTIFDRESDV
MUL_1053|M.ulcerans_Agy99 ---------MTSPLSVGIIGAGPGGLALGILLKNRG-FENFNIFDRESDV
MAV_5119|M.avium_104 -----MPADPMSELSIGIIGAGPGGLALGILLSQAG-FDDFTIFDREDGV
Mflv_4103|M.gilvum_PYR-GCK ---------MAKSLSVGIIGAGPGGLALGIFLRRAG-FDDFTIFDREDGV
Mvan_2243|M.vanbaalenii_PYR-1 -----MTTSMAKTFSVAIIGAGPGGLALGIFLRKAG-FTDFTIFDREDGV
MSMEG_2567|M.smegmatis_MC2_155 ------MSADRMSMSIGIIGAGPGGLALGIFLKKAG-FRDFTIFDREDGV
TH_3452|M.thermoresistible__bu ---------MARNLSVGIIGAGPGGIALGIFLRRAG-FTDFTIFDREDGV
MAB_2077|M.abscessus_ATCC_1997 MSSNFATACRAYDPSIVIIGAGFAGVAMAHRLKKDG-FTNFTILEKAADI
MLBr_00065|M.leprae_Br4923 ----MVVMAETEYLDVVIVGAGISGVSAAWHLQDRCPNKSYVILEKRAGM
: ::*** .*:. . * . * :: .:
Mb0916|M.bovis_AF2122/97 GGTWRDNTYPGLTCDVPSRLYQYSFAKNPNWTQMFSRGGEIQDYLRGIAE
Rv0892|M.tuberculosis_H37Rv GGTWRDNTYPGLTCDVPSRLYQYSFAKNPNWTQMFSRGGEIQDYLRGIAE
MMAR_0403|M.marinum_M GGTWRINTYPGLACDVKSHLYSYSFDLNPGWSRLWSGQPEILAYFQRCAD
MUL_1053|M.ulcerans_Agy99 GGTWRINTYPGLACDVKSHLYSYSFDLNPGWSGLWSGQPEILAYFQRCAD
MAV_5119|M.avium_104 GGTWRINTYPGLACDVKSHLYSYSFDLNAHWSRLWSGQPEILDYFQRCAD
Mflv_4103|M.gilvum_PYR-GCK GGTWRINTYPGLACDVKSHLYSYSFDLNAHWSRLWSGQKEILEYFERCAQ
Mvan_2243|M.vanbaalenii_PYR-1 GGTWRINTYPGLACDVKSHLYSYSFDLNAHWSRMWSGQEEILQYFERCAQ
MSMEG_2567|M.smegmatis_MC2_155 GGTWRINTYPGLACDVKSHLYSYSFDLNADWTRLWSSQPEILAYFERCAQ
TH_3452|M.thermoresistible__bu GGTWRINTYPGLACDVKSHLYSYSFELNSEWTRLWPAQPEILRYFERCAQ
MAB_2077|M.abscessus_ATCC_1997 GGVWRDNTYPGAACDVPSALYSLSYKPNPRWSRRYAEQPEILKYLQQLVE
MLBr_00065|M.leprae_Br4923 GGTWDLFRYPGIRSDSDMYTLGFRFRPWTKCQAIADGKP-ILEYIKSTAV
**.* *** .* : . * *:. .
Mb0916|M.bovis_AF2122/97 RYGLRHRIRFGATVVSARFDDGR--WVLRTDSGTES-----TVDFLISAT
Rv0892|M.tuberculosis_H37Rv RYGLRHRIRFGATVVSARFDDGR--WVLRTDSGTES-----TVDFLISAT
MMAR_0403|M.marinum_M RYGLRPHLRLSTEIRSARWESQTRQWTLSTADGEQH-----QFSVVVSAV
MUL_1053|M.ulcerans_Agy99 RYELRPHLRLGTEIRSARWESQTRQWTLSTADGEQH-----QFSVVVSVV
MAV_5119|M.avium_104 KYGLGPHLRLGTEIRSAHWDADTQRWRLTTASGHRH-----HFDVVVSAV
Mflv_4103|M.gilvum_PYR-GCK RYRLQEKLRCNTEIVSARWVPSERRWRLRTSTGAEH-----SFDVVVSAV
Mvan_2243|M.vanbaalenii_PYR-1 RYRLPDNLQLNTEIVSARWGSETRTWTLTTAGGEEH-----TFDIVVSAI
MSMEG_2567|M.smegmatis_MC2_155 RHQLESHLVLGTEITSARWDTDG--WVLTTSGGDEQ-----RFDFVVSAV
TH_3452|M.thermoresistible__bu RHRLGPHLRLNTEITSARWNPTSRQWMLTTGAGEQH-----NFDVVVSAV
MAB_2077|M.abscessus_ATCC_1997 SGGLAAHLRTQTEVVAMTFDDQLGRWTLVTNSNETI-----TCDVVVSAV
MLBr_00065|M.leprae_Br4923 MHGIDKYIRLNHKVTGADWSSIENRWTVQVENNGTPRMISCSFLFLCSGY
: : : . : * : . . .: *
Mb0916|M.bovis_AF2122/97 GVLHHPRIPPIAGLDDFRGTVFHSARWDHTVPLLGRRIAVIGTGSTGVQL
Rv0892|M.tuberculosis_H37Rv GVLHHPRIPPIAGLDDFRGTVFHSARWDHTVPLLGRRIAVIGTGSTGVQL
MMAR_0403|M.marinum_M GIFSRPAYPDLVEQQRFTGTVMHSSRWDHSVPLAGARIAVLGTGSTAAQL
MUL_1053|M.ulcerans_Agy99 GIFSRPAYPDLVEQQRFTGTVMHSSRWDHSVPLAGARIAVLGTGSTAAQL
MAV_5119|M.avium_104 GLFTRPLLPELVEEEPFTGTVMHSARWDHSIPLHGKRIAVLGTGSTASQL
Mflv_4103|M.gilvum_PYR-GCK GMFTQPVMPDLVEEEPFTGTVMHTARWDHSVDLRGARVAVLGTGSTAAQL
Mvan_2243|M.vanbaalenii_PYR-1 GLFTQPVMPDLVDEEPFTGTVMHTARWDHSVDLRDARVAVLGTGSTAAQL
MSMEG_2567|M.smegmatis_MC2_155 GLFTQPLLPDLVEEEPFTGTVLHTARWDHSIPLAGKKIAVLGTGSTAAQL
TH_3452|M.thermoresistible__bu GMFTRPVMPDLVEEEPFTGTLMHSARWDHGIDLHGKRIAVLGTGSTASQL
MAB_2077|M.abscessus_ATCC_1997 GQLSLPHVPVIADADTFQGPRFHSARWDRSVSLRGKQVAVIGTGASAIQF
MLBr_00065|M.leprae_Br4923 YNYEQGYAPTFLGSEDFTGPIIHPQHWPEDLDYAAKNIVVIGSGATAVTL
* : : * *. :*. :* . : .:.*:*:*::. :
Mb0916|M.bovis_AF2122/97 VCGLAG-VAGKVTMFQRTAQWVLPWP--NPRYSKLARVFHRAFPCLGSLA
Rv0892|M.tuberculosis_H37Rv VCGLAG-VAGKVTMFQRTAQWVLPWP--NPRYSKLARVFHRAFPCLGSLA
MMAR_0403|M.marinum_M VPELAK-VADRVYSIQRSPTWILPKP--DRPYSRWERWVFAHVPFAARLY
MUL_1053|M.ulcerans_Agy99 VPELAK-VADRVYSIQRSPTWILPKP--DRPYSRWERWVFAHVPFAARLY
MAV_5119|M.avium_104 IPELAK-VAERVYSVQRSPTWILPKP--DRPYTRWERWAFAHLPLAKKLY
Mflv_4103|M.gilvum_PYR-GCK VPEVAK-QAAAVYSVQRSPTWVLPKP--DRPYTDREKWMFAHVPFAKKIY
Mvan_2243|M.vanbaalenii_PYR-1 VPEVAK-QAAKVYSVQRSPTWVLPKP--DREYTGREKWMFAHIPLAKKIY
MSMEG_2567|M.smegmatis_MC2_155 VPELAK-VADTVYSVQRSPTWILPKP--DRPYTDRERWVFAHVPLAKKIY
TH_3452|M.thermoresistible__bu IPELAK-IADRVYSVQRSPTWILPKP--DRPYSDRERWVFRHVPFAKRIY
MAB_2077|M.abscessus_ATCC_1997 VPHIVQ-EAEHVTLYQRTAPWILPKW--DSRYGVLHDRVSELLPMALRLE
MLBr_00065|M.leprae_Br4923 VPALANSGAKHVTMLQRSPTYIVSQPAKDKIAARLNRWLPDKYAYTAVRW
: :. * * **:. :::. : .
Mb0916|M.bovis_AF2122/97 YKAYSLSFETFAVALSNPGLHRKLVGAVCRASLRR-VRDPRLRRALTPDY
Rv0892|M.tuberculosis_H37Rv YKAYSLSFETFAVALSNPGLHRKLVGAVCRASLRR-VRDPRLRRALTPDY
MMAR_0403|M.marinum_M RTRLWLRSESNISVIEHGSPKTKEFTELALRMLENTVSDPQLRRQLTPDH
MUL_1053|M.ulcerans_Agy99 RTRLWLRSESNISVIEHGSPKTKEFTELALRMLENTVSDPQLRRQLTPDH
MAV_5119|M.avium_104 RTRLWLRSESNISVIEHGSEKTGQFTNIALGLLEASVPDEELRRKLTPDH
Mflv_4103|M.gilvum_PYR-GCK RTRLWLRSESNISVIEHGSDKTQEFKSIALRTLEATVSDDELRARLTPDH
Mvan_2243|M.vanbaalenii_PYR-1 RTRLWLRSESNISVIENGSDKTEEFKGIALRTLEATVADDELRAKLTPTH
MSMEG_2567|M.smegmatis_MC2_155 RTRLWLRSESNISVIEHGSDKTQEFRSIALNMLRSTVTDDELRERLTPDH
TH_3452|M.thermoresistible__bu RTRLWLRSEANISVIEDGSEKTEEFKAIALKMLEATVPDEEMRRRLTPDH
MAB_2077|M.abscessus_ATCC_1997 RFAVWLIFELLAVTLVDAKPLSRVLGAIARRHLHRQVASPSLREQLMPSD
MLBr_00065|M.leprae_Br4923 KNILRQSALYGACQKWPQRMRNILLGHVARRLPKGYDVQKHFGPHYNPWE
. :. . . : *
Mb0916|M.bovis_AF2122/97 EPMCKRLVMSGGFYRAIQRDDVELVTAGIDHVEHRGIVTDDGVLHEVDVI
Rv0892|M.tuberculosis_H37Rv EPMCKRLVMSGGFYRAIQRDDVELVTAGIDHVEHRGIVTDDGVLHEVDVI
MMAR_0403|M.marinum_M PMGCKRLVFSSEFLTALARPNVELVTSPARYLRQRSLVTADGAEYDVDVV
MUL_1053|M.ulcerans_Agy99 PMGCKRLVFSSEFLTALTRPNVELVTSPARYLRQRSLVTADGAEYDVDVV
MAV_5119|M.avium_104 PMGCKRLVFSSDYLPALTRPNVEVLTSPARSLRRRSLVTEDGTEREVDLV
Mflv_4103|M.gilvum_PYR-GCK PLGCKRLVFATDYLKTLTEPHVDVVSSPARALRSRSLVTEDGTELDVDVV
Mvan_2243|M.vanbaalenii_PYR-1 PLGCKRLVFATDYLQTLTQPHVEVVSSPARSLRSRSLVTEDGTELDVDVV
MSMEG_2567|M.smegmatis_MC2_155 PLGCKRLVFSSDFIPTLTRPNVEVVSSPARALRSRSLVTEDGRELDVDIV
TH_3452|M.thermoresistible__bu PLGCKRLVFSSDYLAALMRPNVEVVSSPARALRGDTLITEDGTERRVDVV
MAB_2077|M.abscessus_ATCC_1997 APGCKRVLFSNDYYPAIASDRVSLVPKAIAELCDNGVKTVDGEFRPADVV
MLBr_00065|M.leprae_Br4923 QRLC--LVPDGDLFRAIRKGTVDMVTDAIDRFTSTGIRLKSGNELRADII
* :: :: *.::. . : .* .*::
Mb0916|M.bovis_AF2122/97 VLATGFDSHAFFRPMQLTGRDGIRIDDVWQDGPHAHQTVAIPGFPNFFMM
Rv0892|M.tuberculosis_H37Rv VLATGFDSHAFFRPMQLTGRDGIRIDDVWQDGPHAHQTVAIPGFPNFFMM
MMAR_0403|M.marinum_M VCATGYAAADYLGQLEVLGEDGAGLHEVWRDGAHAYLGMAVPGFPNFFML
MUL_1053|M.ulcerans_Agy99 VCATGYAAADYLGQLEVLGEDGAGLHEVWRDGAHAYLGMAVPGFPNFFML
MAV_5119|M.avium_104 VCATGYAAADYLGELDVTGEHGVTLREVWRDGAYAYLGMAVPGFPNFFML
Mflv_4103|M.gilvum_PYR-GCK LCATGYAAADYLGQIDVRGADDIPLSQTWRDGAFAYLGMSVPGYPNFFML
Mvan_2243|M.vanbaalenii_PYR-1 LCATGYAAADYLGQIEVRGADDALLSDTWRDGAFAYLGMAVPGYPNFFML
MSMEG_2567|M.smegmatis_MC2_155 ACATGYAAADYLGQIEVTGEGGIRLHDVWRDGAYAYLGMTVPGFPNFFML
TH_3452|M.thermoresistible__bu VCATGYAAADYLGQIEVVGERQRSLREVWRDGAYAYLGMTVPGFPNFFML
MAB_2077|M.abscessus_ATCC_1997 IYGTGFRATDFLAPMSVRGSRGVSLAEVWKTQAYAYLGITVPMFPNLFLL
MLBr_00065|M.leprae_Br4923 VTATGLNLQLFGGAVATVDGQPVDLAQTMS-----YKGMMLSGLPNMIYT
.** : : . : :. : : :. **::
Mb0916|M.bovis_AF2122/97 LGPHSPVGNFPLTAVAESQAEHIVQWIKRWRHGEFDTMEPKSAATEAYNT
Rv0892|M.tuberculosis_H37Rv LGPHSPVGNFPLTAVAESQAEHIVQWIKRWRHGEFDTMEPKSAATEAYNT
MMAR_0403|M.marinum_M YGPNTNVGSNSVIFMLEAQARYIVAALAHLRRKSKTYIAVRPGVLAEFMA
MUL_1053|M.ulcerans_Agy99 CGPNTNVGSNSVIFMLEAQARYIVAALAHLRRKSKTYIAVRPGVLAEFIA
MAV_5119|M.avium_104 YGPNTNVGSNSVIFVLEAQARYIVRALKYLRRHRRRYIAVRPAALADFVA
Mflv_4103|M.gilvum_PYR-GCK YGPNTNVGSNSVIFVLEAQARYIVRALKYLRRRNRSYIEVRSDVMKRYLD
Mvan_2243|M.vanbaalenii_PYR-1 YGPNTNVGSNSVIFMLEAQAHYIVRALKYMRRKNRSYIEVRSDVMTRFLE
MSMEG_2567|M.smegmatis_MC2_155 YGPNTNVGSNSVIFVLEAQARYVVRALKHLRRRRKSYVAVKPEVMAQFIA
TH_3452|M.thermoresistible__bu YGPNTNVGSNSVLFILEAQARYVVKALKRLRRRDTSYIAVRPDTAAAFLA
MAB_2077|M.abscessus_ATCC_1997 YGPNTNVGSGSILYMIESQVRHIATLIKAVAAHPGHAIDVRTESAQRYNT
MLBr_00065|M.leprae_Br4923 VG----YTNASWTLKADLVSEFFCRLLNYMNANDFDTVAVEYPGSDVEER
* . . : ... : : .
Mb0916|M.bovis_AF2122/97 VLRAAMPNTVWTTGCDSWYLNKDG-IPEVWPFAPAKHRAMLANLHPEEYD
Rv0892|M.tuberculosis_H37Rv VLRAAMPNTVWTTGCDSWYLNKDG-IPEVWPFAPAKHRAMLANLHPEEYD
MMAR_0403|M.marinum_M KVDRWMTGTVWTTECSNYFRAPNGRVVTQWPRSARSFWGMTRRFKPADFS
MUL_1053|M.ulcerans_Agy99 KVDRWMTGTVWTTECSNYFRAPNGRVVTQWPRSARSFWGMTRRFKPADFS
MAV_5119|M.avium_104 KIDRWMVGTVWTTQCSNYFRAPNGRVVTQWPRSARAFWSMTRRFRPADYR
Mflv_4103|M.gilvum_PYR-GCK KIDSWMQGTVWLTRCSNYFRAPNGRVVTQWPRSARDFWALTRWFRAGDYV
Mvan_2243|M.vanbaalenii_PYR-1 RIDTWMQGTVWLTRCSNYFRAPNGRVVTQWPRSARTFWGLTRRFNPGDYG
MSMEG_2567|M.smegmatis_MC2_155 DIDRWMQGTVWLTRCSSYFRAPNGRVVTQWPRSARALWAMTRRFRAADYL
TH_3452|M.thermoresistible__bu KVDQWMQGKVWSTQCNNYFRAPNGRVVTQWPRSARAFWAMTRRFRSADYL
MAB_2077|M.abscessus_ATCC_1997 RLRRRLRRSVWA-LCASWYRTSSGEIPTNWPGPTLVYRLLTRKPHSGDYV
MLBr_00065|M.leprae_Br4923 PFMDFTPG--YVLRSLDALPKQGSRTPWRLNQNYLRDIRLIRRGKVADEG
. : . . .. : . :
Mb0916|M.bovis_AF2122/97 LRRYAAVRATSRPQSA--------------------------------
Rv0892|M.tuberculosis_H37Rv LRRYAAVRATSRPQSA--------------------------------
MMAR_0403|M.marinum_M FQPAAVFAADGGDRNAGQR-----------------------------
MUL_1053|M.ulcerans_Agy99 FQPAAVFAADGGDRNAGQRWPNPRPSIGWTPCCAPSRRRESTSPRSRS
MAV_5119|M.avium_104 FQAPAVRVPAPAS-EADAR-----------------------------
Mflv_4103|M.gilvum_PYR-GCK FEAPSA--RETISVGAQAEAER--------------------------
Mvan_2243|M.vanbaalenii_PYR-1 FDAPSS--RSRIRVGAQTSVKQP-------------------------
MSMEG_2567|M.smegmatis_MC2_155 FSAPVDGQAQVVEVAAHETVG---------------------------
TH_3452|M.thermoresistible__bu FEPAPD--MSEVSADARPVASR--------------------------
MAB_2077|M.abscessus_ATCC_1997 LRNVGR---LKVGDPAEPSLAD--------------------------
MLBr_00065|M.leprae_Br4923 LLFAKKTTPVTV------------------------------------
: